Research Output

2020

Analysis of O-glycoforms of the IgA1 hinge region by sequential deglycosylation

Ohyama, Y., Yamaguchi, H., Nakajima, K., Mizuno, T., Fukamachi, Y., Yokoi, Y., Tsuboi, N., Inaguma, D., Hasegawa, M., Renfrow, M. B., Novak, J., Yuzawa, Y. & Takahashi, K., 01-12-2020, In : Scientific reports. 10, 1, 671.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Application of a human mesoderm tissue elongation system in vitro derived from human induced pluripotent stem cells to risk assessment for teratogenic chemicals

Ninomiya, H., Intoh, A., Ishimine, H., Onuma, Y., Ito, Y., Michiue, T., Tazaki, A. & Kato, M., 07-2020, In : Chemosphere. 250, 126124.

Research output: Contribution to journalArticle

1 Citation (Scopus)

CD140b and CD73 are markers for human induced pluripotent stem cell-derived erythropoietin-producing cells

Nishimoto, S., Mizuno, T., Takahashi, K., Nagano, F., Yuzawa, Y., Nishiyama, A., Osafune, K., Hitomi, H. & Nagamatsu, T., 01-03-2020, In : FEBS Open Bio. 10, 3, p. 427-433 7 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Glomerular Cellular Interactions Following Disruption of the Glomerular Basement Membrane in IgA Nephropathy: Ultrastructural Analyses by 3-Dimensional Serial Block-Face Scanning Electron Microscopy

Nagai, M., Saitoh, S., Takaki, T., Ohbayashi, T., Hotta, O., Ohno, N. & Joh, K., 01-03-2020, In : Kidney Medicine. 2, 2, p. 222-225 4 p.

Research output: Contribution to journalArticle

Open Access

Mass spectrometry for the identification and analysis of highly complex glycosylation of therapeutic or pathogenic proteins

Ohyama, Y., Nakajima, K., Renfrow, M. B., Novak, J. & Takahashi, K., 02-04-2020, In : Expert Review of Proteomics. 17, 4, p. 275-296 22 p.

Research output: Contribution to journalReview article

Sodium-glucose co-transporter (SGLT) inhibitor restores lost axonal varicosities of the myenteric plexus in a mouse model of high-fat diet-induced obesity

Shimo, S., Saitoh, S., Nguyen, H. B., Thai, T. Q., Ikutomo, M., Muramatsu, K. & Ohno, N., 01-12-2020, In : Scientific reports. 10, 1, 12372.

Research output: Contribution to journalArticle

Open Access
2019

IgA1 hinge-region clustered glycan fidelity is established early during semi-ordered glycosylation by GalNAc-T2

Stewart, T. J., Takahashi, K., Whitaker, R. H., Raska, M., Placzek, W. J., Novak, J. & Renfrow, M. B., 2019, In : Glycobiology. 29, 7, p. 543-556 14 p., cwz007.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Prediction model for cardiovascular events or all-cause mortality in incident dialysis patients

Inaguma, D., Morii, D., Kabata, D., Yoshida, H., Tanaka, A., Koshi-Ito, E., Takahashi, K., Hayashi, H., Koide, S., Tsuboi, N., Hasegawa, M., Shintani, A. & Yuzawa, Y., 01-08-2019, In : PloS one. 14, 8, e0221352.

Research output: Contribution to journalArticle

Open Access

Relationship between history of ischemic stroke and all-cause mortality in incident dialysis patients

Kojima, M., Inaguma, D., Koide, S., Koshi-Ito, E., Takahashi, K., Hayashi, H., Tsuboi, N., Hasegawa, M. & Yuzawa, Y., 01-09-2019, In : Nephron. 143, 1, p. 43-53 11 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Structural analysis of glycans (analytical and detection methods)

Nakajima, K., Takahashi, K., Yamaguchi, Y., Shinohara, Y., Kaji, H., Furukawa, J. I., Suzuki, A., Haga, Y., Ueda, K., Suda, Y., Hirabayashi, Y., Furukawa, K., Yamamoto, K., Kawasaki, T. & Honke, K., 01-01-2019, Glycoscience: Basic Science to Applications: Insights from the Japan Consortium for Glycobiology and Glycotechnology (JCGG). Springer Singapore, p. 3-33 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Aortic stenosis is a risk factor for all-cause mortality in patients on dialysis: A multicenter prospective cohort analysis

Inaguma, D., Sasakawa, Y., Suzuki, N., Ito, E., Takahashi, K., Hayashi, H., Koide, S., Hasegawa, M., Yuzawa, Y., Tamai, H., Tsutsui, S., Ueda, T., Narita, Y., Sofue, F., Hirano, Y., Motokawa, M., Miwa, M., Suzuki, N., Kojima, S., Takatsu, H. & 60 others, Akahori, T., Murakami, K., Shimano, Y., Miyazaki, T., Baba, K., Iida, Y., Endo, H., Furuya, R., Aoyama, I., Mizutani, Y., Seno, H., Nagaya, T., Kasuga, H., Sugiyama, S., Kojima, K., Fujisawa, K., Naruse, T., Ishida, O., Oishi, H., Ono, A., Shimizu, H., Kato, K., Ito, I., Yasutomi, S., Yamazaki, C., Yasuda, K., Matsuoka, T., Tsuruta, Y., Mizuno, M., Ono, M., Okada, M., Tanoue, A., Obayashi, T., Yokoyama, I., Kushimoto, H., Hasegawa, H., Kawasumi, M., Nomura, A., Sakurauchi, Y., Yamashita, M., Asada, H., Ohara, K., Koyabu, S., Tada, M., Sato, F., Yamaguchi, S., Ogawa, H., Ota, Y., Matsumoto, Y., Otsuka, S., Namii, Y., Kasai, Y., Kato, N., Nakayama, M., Sato, H., Inaba, S., Shibata, M., Yamashita, H., Yamamoto, J. & Yamaguchi, M., 03-04-2018, In : BMC Nephrology. 19, 1, 80.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Association between resting heart rate just before starting the first dialysis session and mortality: A multicentre prospective cohort study

AICOPP group, 05-2018, In : Nephrology. 23, 5, p. 461-468 8 p.

Research output: Contribution to journalArticle

Chondroitin sulfate protects vascular endothelial cells from toxicities of extracellular histones

Nagano, F., Mizuno, T., Mizumoto, S., Yoshioka, K., Takahashi, K., Tsuboi, N., Maruyama, S., Yamada, S. & Nagamatsu, T., 05-05-2018, In : European Journal of Pharmacology. 826, p. 48-55 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Detection and identification of potential transglutaminase 2 substrates in the mouse renal glomeruli author names and affiliations

Ito, Y., Tatsukawa, H., Yamaguchi, H., Takahashi, K., Hitomi, K. & Yuzawa, Y., 15-12-2018, In : Archives of Biochemistry and Biophysics. 660, p. 11-19 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Identification and characterization of UDP-mannose in human cell lines and mouse organs: Differential distribution across brain regions and organs

Nakajima, K., Kizuka, Y., Yamaguchi, Y., Hirabayashi, Y., Takahashi, K., Yuzawa, Y. & Taniguchi, N., 01-01-2018, In : Biochemical and Biophysical Research Communications. 495, 1, p. 401-407 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2 Citations (Scopus)

Improved serial sectioning techniques for correlative light-electron microscopy mapping of human langerhans islets

Saitoh, S., Ohno, N., Saitoh, Y., Terada, N., Shimo, S., Aida, K., Fujii, H., Kobayashi, T. & Ohno, S., 2018, In : Acta Histochemica et Cytochemica. 51, 1, p. 9-20 12 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Mass spectrometry-based approach for development of biomarkers in IgA nephropathy: a pilot trial

Kondo, A., Takahashi, K., Yamaguchi, H., Yoshida, Y., Mizuno, T., Nakajima, K., Hayashi, H., Koide, S., Inaguma, D., Hasegawa, M., Hiki, Y. & Yuzawa, Y., 2018, In : Fujita medical journal. 4, 2, p. 36-41 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2 Citations (Scopus)

Serum phosphate level at initiation of dialysis is associated with all-cause mortality: a multicenter prospective cohort study

AICOPP group, 01-11-2018, In : Renal failure. 40, 1, p. 475-482 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Subarachnoid hemorrhage induces neuronal nitric oxide synthase phosphorylation at Ser1412 in the dentate gyrus of the rat brain

Wada, K., Osuka, K., Watanabe, Y., Usuda, N., Fukasawa, M., Araki, Y., Okamoto, S. & Wakabayashi, T., 01-12-2018, In : Nitric Oxide - Biology and Chemistry. 81, p. 67-74 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression

Kasai, S., Furuichi, Y., Ando, N., Kagami, K., Abe, M., Nakane, T., Goi, K., Inukai, T., Saitoh, S., Ohno, S., Okazaki, S., Nagano, O., Saya, H. & Sugita, K., 01-06-2017, In : Cell death & disease. 8, 6, p. e2857

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
4 Citations (Scopus)

Relationship between serum calcium level at dialysis initiation and subsequent prognosis

Inaguma, D., Koide, S., Takahashi, K., Hayashi, H., Hasegawa, M., Yuzawa, Y., Tanaka, A., Murata, M., Shinjo, H., Otsuka, Y., Takeda, A., Tamai, H., Naruse, T., Kurata, K., Oishi, H., Aoyama, I., Ogawa, H., Kushimoto, H., Shimizu, H., Yamamoto, J. & 8 others, Kurata, H., Yamakawa, T., Yaomura, T., Kasuga, H., Ichida, S., Maruyama, S., Matsuo, S. & Kato, N., 30-01-2017, In : Renal Replacement Therapy. 3, 1, 2.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2016

A fatal case of metformin-associated lactic acidosis

Ozeki, T., Kawato, R., Watanabe, M., Minatoguchi, S., Murai, Y., Ryuge, A., Takasugi, K., Hamada, T., Oyama, Y., Nomura, A., Tomino, T., Shimizu, H. & Fujita, Y., 01-04-2016, In : Internal Medicine. 55, 7, p. 775-778 4 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

A retrospective study on the outcomes of MPO-ANCA-associated vasculitis in dialysis-dependent patients

Hasegawa, M., Hattori, K., Sugiyama, S., Asada, H., Yamashita, H., Takahashi, K., Hayashi, H., Koide, S., Sato, W. & Yuzawa, Y., 02-01-2016, In : Modern Rheumatology. 26, 1, p. 110-114 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Basic study on a soft tactile sensor based on subcutaneous tissue with collagen fibers

Sonoi, Y., Tanaka, Y., Hashimoto, M., Fukasawa, M., Usuda, N., Otake, Y., Fukumoto, M. & Sano, A., 01-01-2016, Haptics: Perception, Devices, Control, and Applications - 10th International Conference, EuroHaptics 2016, Proceedings. Bello, F., Visell, Y. & Kajimoto, H. (eds.). Springer Verlag, p. 35-43 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9775).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Evidence-based clinical practice guidelines for IgA nephropathy 2014

Yuzawa, Y., Yamamoto, R., Takahashi, K., Katafuchi, R., Tomita, M., Fujigaki, Y., Kitamura, H., Goto, M., Yasuda, T., Sato, M., Urushihara, M., Kondo, S., Kagami, S., Yasuda, Y., Komatsu, H., Takahara, M., Harabuchi, Y., Kimura, K. & Matsuo, S., 01-08-2016, In : Clinical and Experimental Nephrology. 20, 4, p. 511-535 25 p.

Research output: Contribution to journalReview article

17 Citations (Scopus)

Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies

Shimbo, M., Kudo, T., Hamada, M., Jeon, H., Imamura, Y., Asano, K., Okada, R., Tsunakawa, Y., Mizuno, S., Yagami, K. I., Ishikawa, C., Li, H., Shiga, T., Ishida, J., Hamada, J., Murata, K., Ishimaru, T., Hashimoto, M., Fukamizu, A., Yamane, M. & 21 others, Ikawa, M., Morita, H., Shinohara, M., Asahara, H., Akiyama, T., Akiyama, N., Sasanuma, H., Yoshida, N., Zhou, R., Wang, Y. Y., Ito, T., Kokubu, Y., Noguchi, T. A. K., Ishimine, H., Kurisaki, A., Shiba, D., Mizuno, H., Shirakawa, M., Ito, N., Takeda, SI. & Takahashi, S., 2016, In : Experimental animals. 65, 2, p. 175-187 13 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Heterogeneity of aberrant O-glycosylation of IgA1 in IgA nephropathy

Novak, J., Takahashi, K., Suzuki, H., Reily, C., Stewart, T., Ueda, H., Yamada, K., Moldoveanu, Z., Hastings, M. C., Wyatt, R. J., Mestecky, J., Raska, M., Julian, B. A. & Renfrow, M. B., 10-03-2016, Pathogenesis and Treatment in IgA Nephropathy: An International Comparison. Springer Japan, p. 53-68 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

In a retrospective international study, circulating MIR-148b and let-7b were found to be serum markers for detecting primary IgA nephropathy

Serino, G., Pesce, F., Sallustio, F., De Palma, G., Cox, S. N., Curci, C., Zaza, G., Lai, K. N., Leung, J. C. K., Tang, S. C. W., Papagianni, A., Stangou, M., Goumenos, D., Gerolymos, M., Takahashi, K., Yuzawa, Y., Maruyama, S., Imai, E. & Schena, F. P., 01-03-2016, In : Kidney International. 89, 3, p. 683-692 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Ischemic acute tubular necrosis due to diltiazem overdose

Ryuge, A., Shimizu, H., Ohyama, Y., Yamaguchi, M., Nomura, A., Maruyama, S., Kitamura, H. & Fujita, Y., 2016, In : Internal Medicine. 55, 9, p. 1149-1151 3 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
1 Citation (Scopus)

Lower blood pressure-induced renal hypoperfusion promotes cisplatin-induced nephrotoxicity

Mizuno, T., Hayashi, T., Shimabukuro, Y., Murase, M., Hayashi, H., Ishikawa, K., Takahashi, K., Yuzawa, Y., Yamada, S. & Nagamatsu, T., 14-06-2016, In : Oncology (Switzerland). 90, 6, p. 313-320 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
10 Citations (Scopus)
1 Citation (Scopus)

Rapid specimen preparation to improve the throughput of electron microscopic volume imaging for three-dimensional analyses of subcellular ultrastructures with serial block-face scanning electron microscopy

Thai, T. Q., Nguyen, H. B., Saitoh, S., Wu, B., Saitoh, Y., Shimo, S., Elewa, Y. H. A., Ichii, O., Kon, Y., Takaki, T., Joh, K. & Ohno, N., 01-09-2016, In : Medical Molecular Morphology. 49, 3, p. 154-162 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

The level of IgA antibodies to endothelial cells correlates with histological evidence of disease activity in patients with lupus nephritis

Kondo, A., Takahashi, K., Mizuno, T., Kato, A., Hirano, D., Yamamoto, N., Hayashi, H., Koide, S., Takahashi, H., Hasegawa, M., Hiki, Y., Yoshida, S., Miura, K. & Yuzawa, Y., 10-2016, In : PloS one. 11, 10, e0163085.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015

Cell and tissue damage after skin exposure to ionizing radiation: Short- and long-term effects after a single and fractional doses

Kinoshita, K., Ishimine, H., Shiraishi, K., Kato, H., Doi, K., Kuno, S., Kanayama, K., Mineda, K., Mashiko, T., Feng, J., Nakagawa, K., Kurisaki, A., Itami, S. & Yoshimura, K., 24-09-2015, In : Cells Tissues Organs. 200, p. 240-252 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Collagen fibers induce expansion of receptive field of Pacinian corpuscles

Tanaka, Y., Ito, T., Hashimoto, M., Fukasawa, M., Usuda, N. & Sano, A., 03-06-2015, In : Advanced Robotics. 29, 11, p. 735-741 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Distribution of immunoglobulin-producing cells in immunized mouse spleens

Saitoh, S., Terada, N., Ohno, N. & Ohno, S., 01-01-2015, In Vivo Cryotechnique in Biomedical Research and Application for Bioimaging of Living Animal Organs. Springer Japan, p. 51-56 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Immunohistochemical analysis of various serum proteins in living mouse thymus

Bai, Y., Wu, B., Terada, N., Saitoh, Y., Ohno, N., Saitoh, S. & Ohno, S., 01-01-2015, In Vivo Cryotechnique in Biomedical Research and Application for Bioimaging of Living Animal Organs. Springer Japan, p. 87-92 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter