Research Output

1984

U1 RNA-protein complex preferentially binds to both 5' and 3' splice junction sequences in RNA or single-stranded DNA

Tatei, K., Takemura, K., Mayeda, A., Fujiwara, Y., Tanaka, H., Ishihama, A. & Ohshima, Y., 01-12-1984, In : Proceedings of the National Academy of Sciences of the United States of America. 81, 20 I, p. 6281-6285 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
1985

Studies on the recognition factors for the splice junction in mRNA precursor

Tatei, K., Mayeda, A., Takemura, K., Kitayama, H. & Ohshima, Y., 01-12-1985, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 30, 14 Suppl, p. 1695-1708 14 p.

Research output: Contribution to journalArticle

1986

Messenger RNA splicing: Role of small nuclear RNA-protein complexes

Ohshima, Y., Tatei, K., Takemura, K., Mayeda, A. & Kitayama, H., 1986, In : Advances in Biophysics. 21, C, p. 255-265 11 p.

Research output: Contribution to journalArticle

Three distinct activities possibly involved in mRNA splicing are found in a nuclear fraction lacking U1 and U2 RNA

Mayeda, A., Tatei, K., Kitayama, H., Takemura, K. & Ohshima, Y., 11-04-1986, In : Nucleic Acids Research. 14, 7, p. 3045-3057 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
1988

Short donor site sequences inserted within the intron of β-globin pre-mRNA serve for splicing in vitro

Mayeda, A. & Ohshima, Y., 01-01-1988, In : Molecular and Cellular Biology. 8, 10, p. 4484-4491 8 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
1990

Surveying Cis-acting sequences of pre-mRNA by adding antisense 2'-o-methyl oligoribonucleotides to a splicing reaction

Mayeda, A., Hayase, Y., Inoue, H., Ohtsuka, E. & Ohshima, Y., 09-1990, In : Journal of Biochemistry. 108, 3, p. 399-405 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
10 Citations (Scopus)
1991

Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

Krainer, A. R., Mayeda, A., Kozak, D. & Binns, G., 26-07-1991, In : Cell. 66, 2, p. 383-394 12 p.

Research output: Contribution to journalArticle

378 Citations (Scopus)

Long-term storage of concentrated Tris-borate-EDTA electrophoresis buffers without precipitation

Maeda, A. & Krainer, A. R., 27-02-1991, In : BioTechniques. 10, 2, 1 p.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)
1992
184 Citations (Scopus)

Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2

Maeda, A. & Krainer, A. R., 24-01-1992, In : Cell. 68, 2, p. 365-375 11 p.

Research output: Contribution to journalArticle

545 Citations (Scopus)

Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing

Mayeda, A., Zahler, A. M., Krainer, A. R. & Roth, M. B., 15-02-1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 4, p. 1301-1304 4 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer

Sun, Q., Mayeda, A., Hampson, R. K., Krainer, A. R. & Rottman, F. M., 01-12-1993, In : Genes and Development. 7, 12 B, p. 2598-2608 11 p.

Research output: Contribution to journalArticle

235 Citations (Scopus)

Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF

Mayeda, A., Helfman, D. M. & Krainer, A. R., 05-1993, In : Molecular and Cellular Biology. 13, 5, p. 2993-3001 9 p.

Research output: Contribution to journalArticle

185 Citations (Scopus)

Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF

Eperon, I. C., Ireland, D. C., Smith, R. A., Mayeda, A. & Krainer, A. R., 01-01-1993, In : EMBO Journal. 12, 9, p. 3607-3617 11 p.

Research output: Contribution to journalArticle

155 Citations (Scopus)

Position-specific chondrogenesis of chick limb bud cells in culture.

Ide, H., Wada, N., Kameyama, T. & Uchiyama, K., 1993, In : Progress in clinical and biological research. 383 B, p. 475-484 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
1994

Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors

O'Keefe, R. T., Mayeda, A., Sadowski, C. L., Krainer, A. R. & Spector, D. L., 02-1994, In : Journal of Cell Biology. 124, 3, p. 249-260 12 p.

Research output: Contribution to journalArticle

146 Citations (Scopus)
1996

Identification of a neuronal cell surface molecule, plexin, in mice

Kameyama, T., Murakami, Y., Suto, F., Kawakami, A., Takagi, S., Hirata, T. & Fujisawa, H., 13-09-1996, In : Biochemical and Biophysical Research Communications. 226, 2, p. 524-529 6 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Identification of plexin family molecules in mice

Kameyama, T., Murakami, Y., Suto, F., Kawakami, A., Takagi, S., Hirata, T. & Fujisawa, H., 13-09-1996, In : Biochemical and Biophysical Research Communications. 226, 2, p. 396-402 7 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Pre-mRNA splicing in plants: Characterization of Ser/Arg splicing factors

Lopato, S., Mayeda, A., Krainer, A. R. & Barta, A., 02-04-1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 7, p. 3074-3079 6 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
1997

Crystallization and preliminary X-ray diffraction studies of UP1, the two-RRM domain of hnRNP A1

Jokhan, L., Dong, A. P., Mayeda, A., Krainer, A. R. & Xu, R. M., 01-01-1997, In : Acta Crystallographica Section D: Biological Crystallography. 53, 5, p. 615-618 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs

Xu, R. M., Jokhan, L., Cheng, X., Mayeda, A. & Krainer, A. R., 01-01-1997, In : Structure. 5, 4, p. 559-570 12 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Function of a cell adhesion molecule, plexin, in neuron network formation

Fujisawa, H., Ohta, K., Kameyama, T. & Murakami, Y., 01-01-1997, In : Developmental Neuroscience. 19, 1, p. 101-105 5 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
10 Citations (Scopus)

RCC1 and nuclear organization

Huang, S., Mayeda, A., Krainer, A. R. & Spector, D. L., 06-1997, In : Molecular Biology of the Cell. 8, 6, p. 1143-1157 15 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins

Chandler, S. D., Mayeda, A., Yeakley, J. M., Krainer, A. R. & Fu, X. D., 15-04-1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 8, p. 3596-3601 6 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)
1998

Distinct functions of the closely related tandem RNA-recognition motifs of hnRNP A1

Mayeda, A., Munroe, S. H., Xu, R. M. & Krainer, A. R., 01-09-1998, In : RNA. 4, 9, p. 1111-1123 13 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
1999

Characterization of a SR protein from Trypanosoma brucei with homology to RNA-binding cis-splicing proteins

Ismaïli, N., Pérez-Morga, D., Walsh, P., Mayeda, A., Pays, A., Tebabi, P., Krainer, A. R. & Pays, E., 30-07-1999, In : Molecular and Biochemical Parasitology. 102, 1, p. 103-115 13 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Evidence for the function of an exonic splicing enhancer after the first catalytic step of pre-mRNA splicing

Chew, S. L., Liu, H. X., Mayeda, A. & Krainer, A. R., 14-09-1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 19, p. 10655-10660 6 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing

Caputi, M., Mayeda, A., Krainer, A. R. & Zahler, A. M., 15-07-1999, In : EMBO Journal. 18, 14, p. 4060-4067 8 p.

Research output: Contribution to journalArticle

217 Citations (Scopus)

Mammalian in vitro splicing assays.

Mayeda, A. & Krainer, A. R., 1999, In : Methods in molecular biology (Clifton, N.J.). 118, p. 315-321 7 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Preparation of HeLa cell nuclear and cytosolic S100 extracts for in vitro splicing.

Mayeda, A. & Krainer, A. R., 1999, In : Methods in molecular biology (Clifton, N.J.). 118, p. 309-314 6 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Purification and characterization of human RNPS1: A general activator of pre-mRNA splicing

Mayeda, A., Badolato, J., Kobayashi, R., Zhang, M. Q., Gardiner, E. M. & Krainer, A. R., 16-08-1999, In : EMBO Journal. 18, 16, p. 4560-4570 11 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)

Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements

Mayeda, A., Screaton, G. R., Chandler, S. D., Fu, X. D. & Krainer, A. R., 03-1999, In : Molecular and Cellular Biology. 19, 3, p. 1853-1863 11 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs)

Koizumi, J., Okamoto, Y., Onogi, H., Mayeda, A., Krainer, A. R. & Hagiwara, M., 16-04-1999, In : Journal of Biological Chemistry. 274, 16, p. 11125-11131 7 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)
2000
12 Citations (Scopus)

Mapping the SF2/ASF binding sites in the bovine growth hormone exonic splicing enhancer

Dirksen, W. P., Li, X., Mayeda, A., Krainer, A. R. & Rottman, F. M., 15-09-2000, In : Journal of Biological Chemistry. 275, 37, p. 29170-29177 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Selection of alternative 5' splice sites: Role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1

Eperon, I. C., Makarova, O. V., Mayeda, A., Munroe, S. H., Caceres, J. F., Hayward, D. G. & Krainer, A. R., 11-11-2000, In : Molecular and Cellular Biology. 20, 22, p. 8303-8318 16 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)
2001

Characterization of Two Evolutionarily Conserved, Alternatively Spliced Nuclear Phosphoproteins, NFAR-1 and -2, that Function in mRNA Processing and Interact with the Double-stranded RNA-dependent Protein Kinase, PKR

Saunders, L. R., Perkins, D. J., Balachandran, S., Michaels, R., Ford, R., Mayeda, A. & Barber, G. N., 24-08-2001, In : Journal of Biological Chemistry. 276, 34, p. 32300-32312 13 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Differential expression of plexin-A subfamily members in the mouse nervous system

Murakami, Y., Suto, F., Shimizu, M., Shinoda, T., Kameyama, T. & Fujisawa, H., 06-03-2001, In : Developmental Dynamics. 220, 3, p. 246-258 13 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins

Zhu, J., Mayeda, A. & Krainer, A. R., 01-01-2001, In : Molecular Cell. 8, 6, p. 1351-1361 11 p.

Research output: Contribution to journalArticle

267 Citations (Scopus)

RNA splicing at human immunodeficiency virus type 1 3′ splice site A2 is regulated by binding of hnRNP A/B proteins to an exonic splicing silencer element

Bilodeau, P. S., Domsic, J. K., Mayeda, A., Krainer, A. R. & Stoltzfus, C. M., 31-08-2001, In : Journal of Virology. 75, 18, p. 8487-8497 11 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)

Serine-Arginine (SR) Protein-like Factors That Antagonize Authentic SR Proteins and Regulate Alternative Splicing

Cowper, A. E., Cáceres, J. F., Mayeda, A. & Screaton, G. R., 28-12-2001, In : Journal of Biological Chemistry. 276, 52, p. 48908-48914 7 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

ZNF265 - A novel spliceosomal protein able to induce alternative splicing

Adams, D. J., Van Der Weyden, L., Mayeda, A., Stamm, S., Morris, B. J. & Rasko, J. E. J., 09-07-2001, In : Journal of Cell Biology. 154, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
2002

Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch

Hou, V. C., Lersch, R., Gee, S. L., Ponthier, J. L., Lo, A. J., Wu, M., Turck, C. W., Koury, M., Krainer, A. R., Mayeda, A. & Conboy, J. G., 15-11-2002, In : EMBO Journal. 21, 22, p. 6195-6204 10 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

High prevalence of simian T-lymphotropic virus type L in wild Ethiopian baboons

Takemura, T., Yamashita, M., Shimada, M. K., Ohkura, S., Shotake, T., Ikeda, M., Miura, T. & Hayami, M., 05-02-2002, In : Journal of Virology. 76, 4, p. 1642-1648 7 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Mitochondrial sequence diversity within a subspecies of savanna monkeys (Cercopithecus aethiops) is similar to that between subspecies

Shimada, M. K., Terao, K. & Shotake, T., 01-01-2002, In : Journal of Heredity. 93, 1, p. 9-18 10 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)
19 Citations (Scopus)
2003

A novel rat orthologue and homologue for the Drosophila crooked neck gene in neural stem cells and their immediate descendants

Amada, N., Tezuka, T., Mayeda, A., Araki, K., Takei, N., Todokoro, K. & Nawa, H., 01-05-2003, In : Journal of Biochemistry. 133, 5, p. 615-623 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)