Research Output

1985

Studies on the recognition factors for the splice junction in mRNA precursor

Tatei, K., Mayeda, A., Takemura, K., Kitayama, H. & Ohshima, Y., 01-12-1985, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 30, 14 Suppl, p. 1695-1708 14 p.

Research output: Contribution to journalArticle

1986

Three distinct activities possibly involved in mRNA splicing are found in a nuclear fraction lacking U1 and U2 RNA

Mayeda, A., Tatei, K., Kitayama, H., Takemura, K. & Ohshima, Y., 11-04-1986, In : Nucleic acids research. 14, 7, p. 3045-3057 13 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
1988

Short donor site sequences inserted within the intron of β-globin pre-mRNA serve for splicing in vitro

Mayeda, A. & Ohshima, Y., 1988, In : Molecular and Cellular Biology. 8, 10, p. 4484-4491 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
1992
194 Citations (Scopus)
1993

Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF

Mayeda, A., Helfman, D. M. & Krainer, A. R., 05-1993, In : Molecular and Cellular Biology. 13, 5, p. 2993-3001 9 p.

Research output: Contribution to journalArticle

192 Citations (Scopus)

Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF

Eperon, I. C., Ireland, D. C., Smith, R. A., Mayeda, A. & Krainer, A. R., 1993, In : EMBO Journal. 12, 9, p. 3607-3617 11 p.

Research output: Contribution to journalArticle

161 Citations (Scopus)
1994

Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors

O'Keefe, R. T., Mayeda, A., Sadowski, C. L., Krainer, A. R. & Spector, D. L., 02-1994, In : Journal of Cell Biology. 124, 3, p. 249-260 12 p.

Research output: Contribution to journalArticle

148 Citations (Scopus)

Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins

Mayeda, A., Munroe, S. H., Cáceres, J. F. & Krainer, A. R., 15-11-1994, In : EMBO Journal. 13, 22, p. 5483-5495 13 p.

Research output: Contribution to journalArticle

259 Citations (Scopus)

The C-protein tetramer binds 230 to 240 nucleotides of pre-mRNA and nucleates the assembly of 40S heterogeneous nuclear ribonucleoprotein particles

Huang, M., Rech, J. E., Northington, S. J., Flicker, P. F., Mayeda, A., Krainer, A. R. & LeStourgeon, W. M., 1994, In : Molecular and Cellular Biology. 14, 1, p. 518-533 16 p.

Research output: Contribution to journalArticle

Open Access
58 Citations (Scopus)
1995

Identification and characterization of three members of the human SR family of pre-mRNA splicing factors

Screaton, G. R., Cáceres, J. F., Mayeda, A., Bell, M. V., Plebanski, M., Jackson, D. G., Bell, J. I. & Krainer, A. R., 1995, In : EMBO Journal. 14, 17, p. 4336-4349 14 p.

Research output: Contribution to journalArticle

236 Citations (Scopus)
1996

Pre-mRNA splicing in plants: Characterization of Ser/Arg splicing factors

Lopato, S., Mayeda, A., Krainer, A. R. & Barta, A., 02-04-1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 7, p. 3074-3079 6 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)
1997

RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins

Chandler, S. D., Mayeda, A., Yeakley, J. M., Krainer, A. R. & Fu, X. D., 15-04-1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 8, p. 3596-3601 6 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)
1998

Distinct functions of the closely related tandem RNA-recognition motifs of hnRNP A1

Mayeda, A., Munroe, S. H., Xu, R. M. & Krainer, A. R., 09-1998, In : RNA. 4, 9, p. 1111-1123 13 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors

Hanamura, A., Cáceres, J. F., Mayeda, A., Franza, B. R. & Krainer, A. R., 04-1998, In : RNA. 4, 4, p. 430-444 15 p.

Research output: Contribution to journalArticle

293 Citations (Scopus)
1999

Mammalian in vitro splicing assays.

Mayeda, A. & Krainer, A. R., 1999, In : Methods in molecular biology (Clifton, N.J.). 118, p. 315-321 7 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Preparation of HeLa cell nuclear and cytosolic S100 extracts for in vitro splicing.

Mayeda, A. & Krainer, A. R., 1999, In : Methods in molecular biology (Clifton, N.J.). 118, p. 309-314 6 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)

Purification and characterization of human RNPS1: A general activator of pre-mRNA splicing

Mayeda, A., Badolato, J., Kobayashi, R., Zhang, M. Q., Gardiner, E. M. & Krainer, A. R., 16-08-1999, In : EMBO Journal. 18, 16, p. 4560-4570 11 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)

Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements

Mayeda, A., Screaton, G. R., Chandler, S. D., Fu, X. D. & Krainer, A. R., 03-1999, In : Molecular and Cellular Biology. 19, 3, p. 1853-1863 11 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)

The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs)

Koizumi, J., Okamoto, Y., Onogi, H., Mayeda, A., Krainer, A. R. & Hagiwara, M., 16-04-1999, In : Journal of Biological Chemistry. 274, 16, p. 11125-11131 7 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)
2000

Selection of alternative 5' splice sites: Role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1

Eperon, I. C., Makarova, O. V., Mayeda, A., Munroe, S. H., Caceres, J. F., Hayward, D. G. & Krainer, A. R., 2000, In : Molecular and Cellular Biology. 20, 22, p. 8303-8318 16 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)
2001

Characterization of Two Evolutionarily Conserved, Alternatively Spliced Nuclear Phosphoproteins, NFAR-1 and -2, that Function in mRNA Processing and Interact with the Double-stranded RNA-dependent Protein Kinase, PKR

Saunders, L. R., Perkins, D. J., Balachandran, S., Michaels, R., Ford, R., Mayeda, A. & Barber, G. N., 24-08-2001, In : Journal of Biological Chemistry. 276, 34, p. 32300-32312 13 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)

Differential expression of plexin-A subfamily members in the mouse nervous system

Murakami, Y., Suto, F., Shimizu, M., Shinoda, T., Kameyama, T. & Fujisawa, H., 06-03-2001, In : Developmental Dynamics. 220, 3, p. 246-258 13 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

RNA splicing at human immunodeficiency virus type 1 3′ splice site A2 is regulated by binding of hnRNP A/B proteins to an exonic splicing silencer element

Bilodeau, P. S., Domsic, J. K., Mayeda, A., Krainer, A. R. & Stoltzfus, C. M., 2001, In : Journal of Virology. 75, 18, p. 8487-8497 11 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)
2002

Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch

Hou, V. C., Lersch, R., Gee, S. L., Ponthier, J. L., Lo, A. J., Wu, M., Turck, C. W., Koury, M., Krainer, A. R., Mayeda, A. & Conboy, J. G., 15-11-2002, In : EMBO Journal. 21, 22, p. 6195-6204 10 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

High prevalence of simian T-lymphotropic virus type L in wild Ethiopian baboons

Takemura, T., Yamashita, M., Shimada, M. K., Ohkura, S., Shotake, T., Ikeda, M., Miura, T. & Hayami, M., 2002, In : Journal of Virology. 76, 4, p. 1642-1648 7 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
19 Citations (Scopus)
2003

A novel rat orthologue and homologue for the Drosophila crooked neck gene in neural stem cells and their immediate descendants

Amada, N., Tezuka, T., Mayeda, A., Araki, K., Takei, N., Todokoro, K. & Nawa, H., 01-05-2003, In : Journal of Biochemistry. 133, 5, p. 615-623 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Human Immunodeficiency Virus Type 1 hnRNP A/B-Dependent Exonic Splicing Silencer ESSV Antagonizes Binding of U2AF65 to Viral Polypyrimidine Tracts

Domsic, J. K., Wang, Y., Mayeda, A., Krainer, A. R. & Stoltzfus, C. M., 12-2003, In : Molecular and Cellular Biology. 23, 23, p. 8762-8772 11 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Induced HMGA 1a expression causes aberrant splicing a Presenilin-2 pre-mRNA in sporadic Alzhiemer's disease

Manabe, T., Katayama, T., Sato, N., Gomi, F., Hitomi, J., Yanagita, T., Kudo, T., Honda, A., Mori, Y., Matsuzaki, S., Imaizumi, K., Mayeda, A. & Tohyama, M., 01-06-2003, In : Cell Death and Differentiation. 10, 6, p. 698-708 11 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)
2004

Allele frequency distribution of the canine dopamine receptor D4 gene exon III and I in 23 breeds

Ito, H., Nara, H., Inoue-Murayama, M., Shimada, M. K., Koshimura, A., Ueda, Y., Kitagawa, H., Takeuchi, Y., Mori, Y., Murayama, Y., Morita, M., Iwasaki, T., Ôta, K., Tanabe, Y. & Ito, S., 01-07-2004, In : Journal of Veterinary Medical Science. 66, 7, p. 815-820 6 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Erratum: Human RNPS1 and Its Associated Factors: A Versatile Alternative Pre-mRNA Splicing Regulator In Vivo (Molecular and Cellular Biology (2004) 24, 3 (1174-1187))

Sakashita, E., Tatsumi, S., Werner, D., Endo, H. & Mayeda, A., 01-04-2004, In : Molecular and Cellular Biology. 24, 7, 1 p.

Research output: Contribution to journalComment/debate

Human RNPS1 and Its Associated Factors: A Versatile Alternative Pre-mRNA Splicing Regulator in Vivo

Sakashita, E., Tatsumi, S., Werner, D., Endo, H. & Mayeda, A., 02-2004, In : Molecular and Cellular Biology. 24, 3, p. 1174-1187 14 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)
2005

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation

Trembley, J. H., Tatsumi, S., Sakashita, E., Loyer, P., Slaughter, C. A., Suzuki, H., Endo, H., Kidd, V. J. & Mayeda, A., 02-2005, In : Molecular and Cellular Biology. 25, 4, p. 1446-1457 12 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Nucleotide sequence comparison of a chromosome rearrangement on human chromosome 12 and the corresponding ape chromosomes

Shimada, M. K., Kim, C. G., Kitano, T., Ferrell, R. E., Kohara, Y. & Saitou, N., 2005, In : Cytogenetic and Genome Research. 108, 1-3, p. 83-90 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2007

HMGA1a: Sequence-specific RNA-binding factor causing sporadic Alzheimer's disease-linked exon skipping of presenilin-2 pre-mRNA

Manabe, T., Ohe, K., Katayama, T., Matsuzaki, S., Yanagita, T., Okuda, H., Bando, Y., Imaizumi, K., Reeves, R., Tohyama, M. & Mayeda, A., 10-2007, In : Genes to Cells. 12, 10, p. 1179-1191 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2008

Distribution and effects of nonsense polymorphisms in human genes

Yamaguchi-Kabata, Y., Shimada, M. K., Hayakawa, Y., Minoshima, S., Chakraborty, R., Gojobori, T. & Imanishi, T., 14-10-2008, In : PloS one. 3, 10, e3393.

Research output: Contribution to journalArticle

31 Citations (Scopus)

The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts

Genome Information Integration Project and H-Invitational 2 Consortium, 01-2008, In : Nucleic acids research. 36, SUPPL. 1, p. D793-D799

Research output: Contribution to journalArticle

55 Citations (Scopus)
2009

[Oncogenic HMGA1a protein causes sporadic Alzheimer's disease-associated aberrant splicing].

Mayeda, A., Manabe, T. & Ohe, K., 01-12-2009, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 54, 16 Suppl, p. 2245-2250 6 p.

Research output: Contribution to journalReview article

Isolation and characterization of post-splicing lariat-intron complexes

Yoshimoto, R., Kataoka, N., Okawa, K. & Ohno, M., 2009, In : Nucleic acids research. 37, 3, p. 891-902 12 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Skewed matrilineal genetic composition in a small wild chimpanzee community

Shimada, M., Hayakawa, S., Fujita, S., Sugiyama, Y. & Saitou, N., 01-04-2009, In : Folia Primatologica. 80, 1, p. 19-32 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

VarySysDB: A human genetic polymorphism database based on all H-InvDB transcripts

Shimada, M. K., Matsumoto, R., Hayakawa, Y., Sanbonmatsu, R., Gough, C., Yamaguchi-Kabata, Y., Yamasaki, C., Imanishi, T. & Gojobori, T., 09-01-2009, In : Nucleic Acids Research. 37, SUPPL. 1, p. D810-D815

Research output: Contribution to journalArticle

13 Citations (Scopus)
2010

A comprehensive survey of human polymorphisms at conserved splice dinucleotides and its evolutionary relationship with alternative splicing

Shimada, M. K., Hayakawa, Y., Takeda, J. I., Gojobori, T. & Imanishi, T., 03-05-2010, In : BMC Evolutionary Biology. 10, 1, 122.

Research output: Contribution to journalArticle

9 Citations (Scopus)
25 Citations (Scopus)

The expression of HMGA1a is increased in lymphoblastoid cell lines from schizophrenia patients

Morikawa, T., Manabe, T., Ito, Y., Yamada, S., Yoshimi, A., Nagai, T., Ozaki, N. & Mayeda, A., 01-05-2010, In : Neurochemistry International. 56, 6-7, p. 736-739 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2011

Competition between a noncoding exon and introns: Gomafu contains tandem UACUAAC repeats and associates with splicing factor-1

Tsuiji, H., Yoshimoto, R., Hasegawa, Y., Furuno, M., Yoshida, M. & Nakagawa, S., 01-05-2011, In : Genes to Cells. 16, 5, p. 479-490 12 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Fluorescence detection of intron lariat RNA with reduction-triggered fluorescent probes

Furukawa, K., Abe, H., Tamura, Y., Yoshimoto, R., Yoshida, M., Tsuneda, S. & Ito, Y., 09-12-2011, In : Angewandte Chemie - International Edition. 50, 50, p. 12020-12023 4 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2012

Detection of pre-mRNA splicing in vitro by an RNA-templated fluorogenic reaction

Tamura, Y., Furukawa, K., Yoshimoto, R., Kawai, Y., Yoshida, M., Tsuneda, S., Ito, Y. & Abe, H., 01-12-2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 23, p. 7248-7251 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles

Miyagawa, R., Tano, K., Mizuno, R. I. E., Nakamura, Y. O., Ijiri, K., Rakwal, R., Shibato, J., Masuo, Y., Mayeda, A., Hirose, T. & Akimitsu, N., 01-04-2012, In : RNA. 18, 4, p. 738-751 14 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)

In Vitro Splicing Assays

Mayeda, A. & Krainer, A. R., 02-02-2012, Alternative pre-mRNA Splicing: Theory and Protocols. Wiley-VCH, p. 320-329 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Mechanistic insights into human pre-mRNA splicing of human ultra-short introns: Potential unusual mechanism identifies G-rich introns

Sasaki-Haraguchi, N., Shimada, M. K., Taniguchi, I., Ohno, M. & Mayeda, A., 29-06-2012, In : Biochemical and Biophysical Research Communications. 423, 2, p. 289-294 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)