Research Output

Article

A comprehensive survey of human polymorphisms at conserved splice dinucleotides and its evolutionary relationship with alternative splicing

Shimada, M. K., Hayakawa, Y., Takeda, J. I., Gojobori, T. & Imanishi, T., 03-05-2010, In : BMC Evolutionary Biology. 10, 1, 122.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation

Trembley, J. H., Tatsumi, S., Sakashita, E., Loyer, P., Slaughter, C. A., Suzuki, H., Endo, H., Kidd, V. J. & Mayeda, A., 02-2005, In : Molecular and Cellular Biology. 25, 4, p. 1446-1457 12 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Allele frequency distribution of the canine dopamine receptor D4 gene exon III and I in 23 breeds

Ito, H., Nara, H., Inoue-Murayama, M., Shimada, M. K., Koshimura, A., Ueda, Y., Kitagawa, H., Takeuchi, Y., Mori, Y., Murayama, Y., Morita, M., Iwasaki, T., Ôta, K., Tanabe, Y. & Ito, S., 01-07-2004, In : Journal of Veterinary Medical Science. 66, 7, p. 815-820 6 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
12 Citations (Scopus)

A novel rat orthologue and homologue for the Drosophila crooked neck gene in neural stem cells and their immediate descendants

Amada, N., Tezuka, T., Mayeda, A., Araki, K., Takei, N., Todokoro, K. & Nawa, H., 01-05-2003, In : Journal of Biochemistry. 133, 5, p. 615-623 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats

Yoshimoto, R., Rahimi, K., Hansen, T. B., Kjems, J. & Mayeda, A., 24-07-2020, In : iScience. 23, 7, 101345.

Research output: Contribution to journalArticle

Open Access
Open Access
1 Citation (Scopus)

Characterization of Two Evolutionarily Conserved, Alternatively Spliced Nuclear Phosphoproteins, NFAR-1 and -2, that Function in mRNA Processing and Interact with the Double-stranded RNA-dependent Protein Kinase, PKR

Saunders, L. R., Perkins, D. J., Balachandran, S., Michaels, R., Ford, R., Mayeda, A. & Barber, G. N., 24-08-2001, In : Journal of Biological Chemistry. 276, 34, p. 32300-32312 13 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)

Competition between a noncoding exon and introns: Gomafu contains tandem UACUAAC repeats and associates with splicing factor-1

Tsuiji, H., Yoshimoto, R., Hasegawa, Y., Furuno, M., Yoshida, M. & Nakagawa, S., 01-05-2011, In : Genes to Cells. 16, 5, p. 479-490 12 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Component of splicing factor SF3b plays a key role in translational control of polyribosomes on the endoplasmic reticulum

Ueno, T., Taga, Y., Yoshimoto, R., Mayeda, A., Hattori, S. & Ogawa-Goto, K., 07-05-2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 19, p. 9340-9349 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Control of the heat stress-induced alternative splicing of a subset of genes by hnRNP K

Yamamoto, K., Furukawa, M. T., Fukumura, K., Kawamura, A., Yamada, T., Suzuki, H., Hirose, T., Sakamoto, H. & Inoue, K., 01-09-2016, In : Genes to Cells. 21, 9, p. 1006-1014 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch

Hou, V. C., Lersch, R., Gee, S. L., Ponthier, J. L., Lo, A. J., Wu, M., Turck, C. W., Koury, M., Krainer, A. R., Mayeda, A. & Conboy, J. G., 15-11-2002, In : EMBO Journal. 21, 22, p. 6195-6204 10 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Detection of pre-mRNA splicing in vitro by an RNA-templated fluorogenic reaction

Tamura, Y., Furukawa, K., Yoshimoto, R., Kawai, Y., Yoshida, M., Tsuneda, S., Ito, Y. & Abe, H., 01-12-2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 23, p. 7248-7251 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Differential expression of plexin-A subfamily members in the mouse nervous system

Murakami, Y., Suto, F., Shimizu, M., Shinoda, T., Kameyama, T. & Fujisawa, H., 06-03-2001, In : Developmental Dynamics. 220, 3, p. 246-258 13 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors

O'Keefe, R. T., Mayeda, A., Sadowski, C. L., Krainer, A. R. & Spector, D. L., 02-1994, In : Journal of Cell Biology. 124, 3, p. 249-260 12 p.

Research output: Contribution to journalArticle

148 Citations (Scopus)

Distinct functions of the closely related tandem RNA-recognition motifs of hnRNP A1

Mayeda, A., Munroe, S. H., Xu, R. M. & Krainer, A. R., 09-1998, In : RNA. 4, 9, p. 1111-1123 13 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Distribution and effects of nonsense polymorphisms in human genes

Yamaguchi-Kabata, Y., Shimada, M. K., Hayakawa, Y., Minoshima, S., Chakraborty, R., Gojobori, T. & Imanishi, T., 14-10-2008, In : PloS one. 3, 10, e3393.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Endogenous multiple exon skipping and back-splicing at the DMD mutation hotspot

Suzuki, H., Aoki, Y., Kameyama, T., Saito, T., Masuda, S., Tanihata, J., Nagata, T., Mayeda, A., Takeda, SI. & Tsukahara, T., 13-10-2016, In : International journal of molecular sciences. 17, 10, 1722.

Research output: Contribution to journalArticle

22 Citations (Scopus)

ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9

Abe, A., Yamamoto, Y., Iba, S., Kanie, T., Okamoto, A., Tokuda, M., Inaguma, Y., Yanada, M., Morishima, S., Mizuta, S., Akatsuka, Y., Okamoto, M., Kameyama, T., Mayeda, A. & Emi, N., 01-03-2016, In : Genes Chromosomes and Cancer. 55, 3, p. 242-250 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Fluorescence detection of intron lariat RNA with reduction-triggered fluorescent probes

Furukawa, K., Abe, H., Tamura, Y., Yoshimoto, R., Yoshida, M., Tsuneda, S. & Ito, Y., 09-12-2011, In : Angewandte Chemie - International Edition. 50, 50, p. 12020-12023 4 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins

Mayeda, A., Munroe, S. H., Cáceres, J. F. & Krainer, A. R., 15-11-1994, In : EMBO Journal. 13, 22, p. 5483-5495 13 p.

Research output: Contribution to journalArticle

259 Citations (Scopus)
194 Citations (Scopus)

Global analysis of pre-mRNA subcellular localization following splicing inhibition by spliceostatin A

Yoshimoto, R., Kaida, D., Furuno, M., Burroughs, A. M., Noma, S., Suzuki, H., Kawamura, Y., Hayashizaki, Y., Mayeda, A. & Yoshida, M., 01-2017, In : RNA. 23, 1, p. 47-57 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

High prevalence of simian T-lymphotropic virus type L in wild Ethiopian baboons

Takemura, T., Yamashita, M., Shimada, M. K., Ohkura, S., Shotake, T., Ikeda, M., Miura, T. & Hayami, M., 2002, In : Journal of Virology. 76, 4, p. 1642-1648 7 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

HMGA1a: Sequence-specific RNA-binding factor causing sporadic Alzheimer's disease-linked exon skipping of presenilin-2 pre-mRNA

Manabe, T., Ohe, K., Katayama, T., Matsuzaki, S., Yanagita, T., Okuda, H., Bando, Y., Imaizumi, K., Reeves, R., Tohyama, M. & Mayeda, A., 10-2007, In : Genes to Cells. 12, 10, p. 1179-1191 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

HMGA1a induces alternative splicing of estrogen receptor alpha in MCF-7 human breast cancer cells

Ohe, K., Miyajima, S., Abe, I., Tanaka, T., Hamaguchi, Y., Harada, Y., Horita, Y., Beppu, Y., Ito, F., Yamasaki, T., Terai, H., Mori, M., Murata, Y., Tanabe, M., Ashida, K., Kobayashi, K., Enjoji, M., Yanase, T., Harada, N., Utsumi, T. & 1 others, Mayeda, A., 09-2018, In : Journal of Steroid Biochemistry and Molecular Biology. 182, p. 21-26 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

HMGA1a induces alternative splicing of the estrogen receptor-alpha gene by trapping U1 snRNP to an upstream pseudo-5' splice site

Ohe, K., Miyajima, S., Tanaka, T., Hamaguchi, Y., Harada, Y., Horita, Y., Beppu, Y., Ito, F., Yamasaki, T., Terai, H., Mori, M., Murata, Y., Tanabe, M., Abe, I., Ashida, K., Kobayashi, K., Enjoji, M., Nomiyama, T., Yanase, T., Harada, N. & 2 others, Utsumi, T. & Mayeda, A., 08-06-2018, In : Frontiers in Molecular Biosciences. 5, JUN, 52.

Research output: Contribution to journalArticle

2 Citations (Scopus)
25 Citations (Scopus)

HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA

Rahman, M. A., Masuda, A., Ohe, K., Ito, M., Hutchinson, D. O., Mayeda, A., Engel, A. G. & Ohno, K., 25-10-2013, In : Scientific reports. 3, 2931.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Human Immunodeficiency Virus Type 1 hnRNP A/B-Dependent Exonic Splicing Silencer ESSV Antagonizes Binding of U2AF65 to Viral Polypyrimidine Tracts

Domsic, J. K., Wang, Y., Mayeda, A., Krainer, A. R. & Stoltzfus, C. M., 12-2003, In : Molecular and Cellular Biology. 23, 23, p. 8762-8772 11 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Human RNPS1 and Its Associated Factors: A Versatile Alternative Pre-mRNA Splicing Regulator in Vivo

Sakashita, E., Tatsumi, S., Werner, D., Endo, H. & Mayeda, A., 02-2004, In : Molecular and Cellular Biology. 24, 3, p. 1174-1187 14 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Identification and characterization of three members of the human SR family of pre-mRNA splicing factors

Screaton, G. R., Cáceres, J. F., Mayeda, A., Bell, M. V., Plebanski, M., Jackson, D. G., Bell, J. I. & Krainer, A. R., 1995, In : EMBO Journal. 14, 17, p. 4336-4349 14 p.

Research output: Contribution to journalArticle

236 Citations (Scopus)

Identification and validation of evolutionarily conserved unusually short pre-mRNA introns in the human genome

Shimada, M. K., Sasaki-Haraguchi, N. & Mayeda, A., 07-05-2015, In : International journal of molecular sciences. 16, 5, p. 10376-10388 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Identification of a novel component C2ORF3 in the lariat-intron complex: Lack of C2ORF3 interferes with pre-mRNA splicing via intron turnover pathway

Yoshimoto, R., Okawa, K., Yoshida, M., Ohno, M. & Kataoka, N., 01-2014, In : Genes to Cells. 19, 1, p. 78-87 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles

Miyagawa, R., Tano, K., Mizuno, R. I. E., Nakamura, Y. O., Ijiri, K., Rakwal, R., Shibato, J., Masuo, Y., Mayeda, A., Hirose, T. & Akimitsu, N., 01-04-2012, In : RNA. 18, 4, p. 738-751 14 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)

Identification of the specific interactors of the human lariat RNA debranching enzyme 1 protein

Masaki, S., Yoshimoto, R., Kaida, D., Hata, A., Satoh, T., Ohno, M. & Kataoka, N., 09-02-2015, In : International journal of molecular sciences. 16, 2, p. 3705-3721 17 p.

Research output: Contribution to journalArticle

Induced HMGA 1a expression causes aberrant splicing a Presenilin-2 pre-mRNA in sporadic Alzhiemer's disease

Manabe, T., Katayama, T., Sato, N., Gomi, F., Hitomi, J., Yanagita, T., Kudo, T., Honda, A., Mori, Y., Matsuzaki, S., Imaizumi, K., Mayeda, A. & Tohyama, M., 01-06-2003, In : Cell Death and Differentiation. 10, 6, p. 698-708 11 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Isolation and characterization of post-splicing lariat-intron complexes

Yoshimoto, R., Kataoka, N., Okawa, K. & Ohno, M., 2009, In : Nucleic acids research. 37, 3, p. 891-902 12 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

MALAT1 long non-coding RNA in cancer

Yoshimoto, R., Mayeda, A., Yoshida, M. & Nakagawa, S., 01-01-2016, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1859, 1, p. 192-199 8 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

Mammalian in vitro splicing assays.

Mayeda, A. & Krainer, A. R., 1999, In : Methods in molecular biology (Clifton, N.J.). 118, p. 315-321 7 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Mechanistic insights into human pre-mRNA splicing of human ultra-short introns: Potential unusual mechanism identifies G-rich introns

Sasaki-Haraguchi, N., Shimada, M. K., Taniguchi, I., Ohno, M. & Mayeda, A., 29-06-2012, In : Biochemical and Biophysical Research Communications. 423, 2, p. 289-294 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF

Mayeda, A., Helfman, D. M. & Krainer, A. R., 05-1993, In : Molecular and Cellular Biology. 13, 5, p. 2993-3001 9 p.

Research output: Contribution to journalArticle

192 Citations (Scopus)

Nested introns in an intron: Evidence of multi-step splicing in a large intron of the human dystrophin pre-mRNA

Suzuki, H., Kameyama, T., Ohe, K., Tsukahara, T. & Mayeda, A., 18-03-2013, In : FEBS Letters. 587, 6, p. 555-561 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Nucleotide sequence comparison of a chromosome rearrangement on human chromosome 12 and the corresponding ape chromosomes

Shimada, M. K., Kim, C. G., Kitano, T., Ferrell, R. E., Kohara, Y. & Saitou, N., 2005, In : Cytogenetic and Genome Research. 108, 1-3, p. 83-90 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

NUP214-RAC1 and RAC1-COL12A1 Fusion in Complex Variant Translocations Involving Chromosomes 6, 7 and 9 in an Acute Myeloid Leukemia Case with DEK-NUP214

Abe, A., Yamamoto, Y., Iba, S., Okamoto, A., Tokuda, M., Inaguma, Y., Yanada, M., Morishima, S., Kanie, T., Tsuzuki, M., Akatsuka, Y., Mizuta, S., Okamoto, M., Kameyama, T., Mayeda, A. & Emi, N., 01-12-2015, In : Cytogenetic and Genome Research. 146, 4, p. 279-284 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF

Eperon, I. C., Ireland, D. C., Smith, R. A., Mayeda, A. & Krainer, A. R., 1993, In : EMBO Journal. 12, 9, p. 3607-3617 11 p.

Research output: Contribution to journalArticle

161 Citations (Scopus)

Prediction of Protein-Destabilizing Polymorphisms by Manual Curation with Protein Structure

Gough, C. A., Homma, K., Yamaguchi-Kabata, Y., Shimada, M. K., Chakraborty, R., Fujii, Y., Iwama, H., Minoshima, S., Sakamoto, S., Sato, Y., Suzuki, Y., Tada-Umezaki, M., Nishikawa, K., Imanishi, T. & Gojobori, T., 26-11-2012, In : PloS one. 7, 11, e50445.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Pre-mRNA splicing in plants: Characterization of Ser/Arg splicing factors

Lopato, S., Mayeda, A., Krainer, A. R. & Barta, A., 02-04-1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 7, p. 3074-3079 6 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Preparation of HeLa cell nuclear and cytosolic S100 extracts for in vitro splicing.

Mayeda, A. & Krainer, A. R., 1999, In : Methods in molecular biology (Clifton, N.J.). 118, p. 309-314 6 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)