Research Output 1984 2019

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9 Citations (Scopus)

A comprehensive survey of human polymorphisms at conserved splice dinucleotides and its evolutionary relationship with alternative splicing

Shimada, M. K., Hayakawa, Y., Takeda, J. I., Gojobori, T. & Imanishi, T., 03-05-2010, In : BMC Evolutionary Biology. 10, 1, 122.

Research output: Contribution to journalArticle

alternative splicing
exons
polymorphism
genetic polymorphism
single nucleotide polymorphism
26 Citations (Scopus)

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation

Trembley, J. H., Tatsumi, S., Sakashita, E., Loyer, P., Slaughter, C. A., Suzuki, H., Endo, H., Kidd, V. J. & Mayeda, A., 01-02-2005, In : Molecular and Cellular Biology. 25, 4, p. 1446-1457 12 p.

Research output: Contribution to journalArticle

RNA Precursors
Phosphorylation
Serine
Exons
Protein Splicing
57 Citations (Scopus)

Allele frequency distribution of the canine dopamine receptor D4 gene exon III and I in 23 breeds

Ito, H., Nara, H., Inoue-Murayama, M., Shimada, M. K., Koshimura, A., Ueda, Y., Kitagawa, H., Takeuchi, Y., Mori, Y., Murayama, Y., Morita, M., Iwasaki, T., Ôta, K., Tanabe, Y. & Ito, S., 01-07-2004, In : Journal of Veterinary Medical Science. 66, 7, p. 815-820 6 p.

Research output: Contribution to journalArticle

Dopamine D4 Receptors
Gene Frequency
exons
gene frequency
Canidae
8 Citations (Scopus)
bootstrapping
topology
user interface
phylogeny
Phylogeny
6 Citations (Scopus)

A novel rat orthologue and homologue for the Drosophila crooked neck gene in neural stem cells and their immediate descendants

Amada, N., Tezuka, T., Mayeda, A., Araki, K., Takei, N., Todokoro, K. & Nawa, H., 01-05-2003, In : Journal of Biochemistry. 133, 5, p. 615-623 9 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Stem cells
Drosophila
Rats
Neck
1 Citation (Scopus)
Open Access
metastasis
cancer
Neoplasm Metastasis
Proteins
Messenger RNA
90 Citations (Scopus)

CDK11 complexes promote pre-mRNA splicing

Hu, D., Maeda, A., Trembley, J. H., Lahti, J. M. & Kidd, V. J., 07-03-2003, In : Journal of Biological Chemistry. 278, 10, p. 8623-8629 7 p.

Research output: Contribution to journalArticle

RNA Precursors
Transcription
Protein Splicing
Phosphorylation
Proteins
30 Citations (Scopus)

Characterization of a SR protein from Trypanosoma brucei with homology to RNA-binding cis-splicing proteins

Ismaïli, N., Pérez-Morga, D., Walsh, P., Maeda, A., Pays, A., Tebabi, P., Krainer, A. R. & Pays, E., 30-07-1999, In : Molecular and Biochemical Parasitology. 102, 1, p. 103-115 13 p.

Research output: Contribution to journalArticle

Trans-Splicing
Protein Splicing
Trypanosoma brucei brucei
Serine
Arginine
218 Citations (Scopus)

Characterization of RNase R-digested cellular RNA source that consists of lariat and circular RNAs from pre-mRNA splicing

Suzuki, H., Zuo, Y., Wang, J., Zhang, M. Q., Malhotra, A. & Mayeda, A., 10-07-2006, In : Nucleic Acids Research. 34, 8, e63.

Research output: Contribution to journalArticle

RNA Precursors
RNA
Introns
Trans-Splicing
Alternative Splicing
98 Citations (Scopus)

Characterization of Two Evolutionarily Conserved, Alternatively Spliced Nuclear Phosphoproteins, NFAR-1 and -2, that Function in mRNA Processing and Interact with the Double-stranded RNA-dependent Protein Kinase, PKR

Saunders, L. R., Perkins, D. J., Balachandran, S., Michaels, R., Ford, R., Mayeda, A. & Barber, G. N., 24-08-2001, In : Journal of Biological Chemistry. 276, 34, p. 32300-32312 13 p.

Research output: Contribution to journalArticle

eIF-2 Kinase
Double-Stranded RNA
Phosphoproteins
RNA Precursors
RNA-Binding Protein FUS
85 Citations (Scopus)

Competition between a noncoding exon and introns: Gomafu contains tandem UACUAAC repeats and associates with splicing factor-1

Tsuiji, H., Yoshimoto, R., Hasegawa, Y., Furuno, M., Yoshida, M. & Nakagawa, S., 01-05-2011, In : Genes to Cells. 16, 5, p. 479-490 12 p.

Research output: Contribution to journalArticle

Tandem Repeat Sequences
Introns
Exons
RNA
Physiological Phenomena
1 Citation (Scopus)

Component of splicing factor SF3b plays a key role in translational control of polyribosomes on the endoplasmic reticulum

Ueno, T., Taga, Y., Yoshimoto, R., Mayeda, A., Hattori, S. & Ogawa-Goto, K., 07-05-2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 19, p. 9340-9349 10 p.

Research output: Contribution to journalArticle

Polyribosomes
Endoplasmic Reticulum
Protein Biosynthesis
Protein Splicing
Messenger RNA
10 Citations (Scopus)

Control of the heat stress-induced alternative splicing of a subset of genes by hnRNP K

Yamamoto, K., Furukawa, M. T., Fukumura, K., Kawamura, A., Yamada, T., Suzuki, H., Hirose, T., Sakamoto, H. & Inoue, K., 01-09-2016, In : Genes to Cells. 21, 9, p. 1006-1014 9 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein K
Alternative Splicing
Hot Temperature
Heat-Shock Response
Exons
4 Citations (Scopus)

Crystallization and preliminary X-ray diffraction studies of UP1, the two-RRM domain of hnRNP A1

Jokhan, L., Dong, A. P., Mayeda, A., Krainer, A. R. & Xu, R. M., 01-01-1997, In : Acta Crystallographica Section D: Biological Crystallography. 53, 5, p. 615-618 4 p.

Research output: Contribution to journalArticle

Crystallization
X-Ray Diffraction
Diffraction
RNA
crystallization
91 Citations (Scopus)

Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs

Xu, R. M., Jokhan, L., Cheng, X., Mayeda, A. & Krainer, A. R., 01-01-1997, In : Structure. 5, 4, p. 559-570 12 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoproteins
RNA
Proteins
RNA Splice Sites
RNA Recognition Motif
54 Citations (Scopus)

Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch

Hou, V. C., Lersch, R., Gee, S. L., Ponthier, J. L., Lo, A. J., Wu, M., Turck, C. W., Koury, M., Krainer, A. R., Mayeda, A. & Conboy, J. G., 15-11-2002, In : EMBO Journal. 21, 22, p. 6195-6204 10 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein Group A-B
Heterogeneous-Nuclear Ribonucleoproteins
Erythropoiesis
RNA Precursors
Exons
8 Citations (Scopus)

Detection of pre-mRNA splicing in vitro by an RNA-templated fluorogenic reaction

Tamura, Y., Furukawa, K., Yoshimoto, R., Kawai, Y., Yoshida, M., Tsuneda, S., Ito, Y. & Abe, H., 01-12-2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 23, p. 7248-7251 4 p.

Research output: Contribution to journalArticle

RNA Precursors
Fluorescence
RNA
RNA Splicing
Messenger RNA
91 Citations (Scopus)

Differential expression of plexin-A subfamily members in the mouse nervous system

Murakami, Y., Suto, F., Shimizu, M., Shinoda, T., Kameyama, T. & Fujisawa, H., 06-03-2001, In : Developmental Dynamics. 220, 3, p. 246-258 13 p.

Research output: Contribution to journalArticle

Semaphorins
Nervous System
Sensory Receptor Cells
Neuropilins
Nerve Tissue
146 Citations (Scopus)

Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors

O'Keefe, R. T., Mayeda, A., Sadowski, C. L., Krainer, A. R. & Spector, D. L., 02-1994, In : Journal of Cell Biology. 124, 3, p. 249-260 12 p.

Research output: Contribution to journalArticle

RNA Precursors
Oligonucleotides
Microinjections
Antibodies
Normal Distribution
40 Citations (Scopus)

Distinct functions of the closely related tandem RNA-recognition motifs of hnRNP A1

Mayeda, A., Munroe, S. H., Xu, R. M. & Krainer, A. R., 01-09-1998, In : RNA. 4, 9, p. 1111-1123 13 p.

Research output: Contribution to journalArticle

Alternative Splicing
Glycine
Proteins
hnRNP A1
RNA Recognition Motif
30 Citations (Scopus)

Distribution and effects of nonsense polymorphisms in human genes

Yamaguchi-Kabata, Y., Shimada, M. K., Hayakawa, Y., Minoshima, S., Chakraborty, R., Gojobori, T. & Imanishi, T., 14-10-2008, In : PloS one. 3, 10, e3393.

Research output: Contribution to journalArticle

Polymorphism
single nucleotide polymorphism
Single Nucleotide Polymorphism
Genes
genetic polymorphism
13 Citations (Scopus)

Divergent haplotypes and human history as revealed in a worldwide survey of X-linked DNA sequence variation

Shimada, M. K., Panchapakesan, K., Tishkoff, S. A., Nato, A. Q. & Hey, J., 01-03-2007, In : Molecular Biology and Evolution. 24, 3, p. 687-698 12 p.

Research output: Contribution to journalArticle

Haplotypes
haplotypes
History
nucleotide sequences
DNA
18 Citations (Scopus)

Endogenous multiple exon skipping and back-splicing at the DMD mutation hotspot

Suzuki, H., Aoki, Y., Kameyama, T., Saito, T., Masuda, S., Tanihata, J., Nagata, T., Mayeda, A., Takeda, SI. & Tsukahara, T., 13-10-2016, In : International journal of molecular sciences. 17, 10, 1722.

Research output: Contribution to journalArticle

splicing
Duchenne Muscular Dystrophy
mutations
RNA
Exons
7 Citations (Scopus)

ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9

Abe, A., Yamamoto, Y., Iba, S., Kanie, T., Okamoto, A., Tokuda, M., Inaguma, Y., Yanada, M., Morishima, S., Mizuta, S., Akatsuka, Y., Okamoto, M., Kameyama, T., Mayeda, A. & Emi, N., 01-03-2016, In : Genes Chromosomes and Cancer. 55, 3, p. 242-250 9 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Leukemia
Granulocyte Colony-Stimulating Factor
Exons
Chemokine CXCL12
45 Citations (Scopus)

Evidence for the function of an exonic splicing enhancer after the first catalytic step of pre-mRNA splicing

Chew, S. L., Liu, H. X., Maeda, A. & Krainer, A. R., 14-09-1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 19, p. 10655-10660 6 p.

Research output: Contribution to journalArticle

RNA Precursors
Alternative Splicing
Exons
Trans-Splicing
Ligation
32 Citations (Scopus)
Bovine papillomavirus 1
Phosphatidylinositol 3-Kinase
RNA Splice Sites
alternative splicing
phosphatidylinositol 3-kinase
262 Citations (Scopus)

Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins

Zhu, J., Maeda, A. & Krainer, A. R., 01-01-2001, In : Molecular Cell. 8, 6, p. 1351-1361 11 p.

Research output: Contribution to journalArticle

Exons
Proteins
Transcriptional Silencer Elements
Heterogeneous-Nuclear Ribonucleoproteins
hnRNP A1
24 Citations (Scopus)

Fluorescence detection of intron lariat RNA with reduction-triggered fluorescent probes

Furukawa, K., Abe, H., Tamura, Y., Yoshimoto, R., Yoshida, M., Tsuneda, S. & Ito, Y., 09-12-2011, In : Angewandte Chemie - International Edition. 50, 50, p. 12020-12023 4 p.

Research output: Contribution to journalArticle

Fluorescein
RNA
Fluorescent Dyes
Introns
Bearings (structural)
9 Citations (Scopus)

Fluvoxamine moderates reduced voluntary activity following chronic dexamethasone infusion in mice via recovery of BDNF signal cascades

Terada, K., Izumo, N., Suzuki, B., Karube, Y., Morikawa, T., Ishibashi, Y., Kameyama, T., Chiba, K., Sasaki, N., Iwata, K., Matsuzaki, H. & Manabe, T., 01-01-2014, In : Neurochemistry International. 69, 1, p. 9-13 5 p.

Research output: Contribution to journalArticle

Fluvoxamine
Brain-Derived Neurotrophic Factor
Dexamethasone
Locomotion
Serotonin Uptake Inhibitors

Fluvoxamine reverses estrogen-dependent decline in voluntary activities and decreased amygdala levels of serotonin in ovariectomized rats

Lshibashi, Y., Lzumo, N., Lwata, K., Morikawa, T., Kameyama, T., Watanabe, Y., Manabe, T. & Matsuzaki, H., 30-06-2016, In : Journal of Brain Science. 46, p. 5-19 15 p.

Research output: Contribution to journalArticle

Fluvoxamine
Amygdala
Serotonin
Estrogens
Brain-Derived Neurotrophic Factor
376 Citations (Scopus)

Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

Krainer, A. R., Maeda, A., Kozak, D. & Binns, G., 26-07-1991, In : Cell. 66, 2, p. 383-394 12 p.

Research output: Contribution to journalArticle

RNA Splice Sites
RNA-Binding Proteins
Alternative Splicing
Drosophila
U1 Small Nuclear Ribonucleoproteins
18 Citations (Scopus)

Function of a cell adhesion molecule, plexin, in neuron network formation

Fujisawa, H., Ohta, K., Kameyama, T. & Murakami, Y., 01-01-1997, In : Developmental Neuroscience. 19, 1, p. 101-105 5 p.

Research output: Contribution to journalArticle

Cell Adhesion Molecules
Neurons
Xenopus
Cysteine
Proto-Oncogene Proteins
235 Citations (Scopus)

General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer

Sun, Q., Mayeda, A., Hampson, R. K., Krainer, A. R. & Rottman, F. M., 01-12-1993, In : Genes and Development. 7, 12 B, p. 2598-2608 11 p.

Research output: Contribution to journalArticle

Alternative Splicing
Introns
RNA Precursors
Exons
RNA Splicing Factors
184 Citations (Scopus)
RNA Splice Sites
RNA Precursors
Proteins
Heterogeneous-Nuclear Ribonucleoproteins
Ribonucleoproteins
10 Citations (Scopus)

Genetic variation of blood proteins within and between local populations of grivet monkey (Cercopithecus aethiops aethiops) in Central ethiopia

Shimada, M. & Shotake, T., 01-01-1997, In : Primates. 38, 4, p. 399-414 16 p.

Research output: Contribution to journalArticle

Cercopithecus aethiops
Ethiopia
blood proteins
monkeys
genetic variation
12 Citations (Scopus)
Cercopithecus aethiops
Ethiopia
mitochondrial DNA
geographical distribution
haplotypes
16 Citations (Scopus)

Global analysis of pre-mRNA subcellular localization following splicing inhibition by spliceostatin A

Yoshimoto, R., Kaida, D., Furuno, M., Burroughs, A. M., Noma, S., Suzuki, H., Kawamura, Y., Hayashizaki, Y., Mayeda, A. & Yoshida, M., 01-2017, In : RNA. 23, 1, p. 47-57 11 p.

Research output: Contribution to journalArticle

RNA Precursors
RNA Splice Sites
Introns
U2 Small Nuclear Ribonucleoproteins
Cyclin-Dependent Kinase Inhibitor p27
36 Citations (Scopus)

High prevalence of simian T-lymphotropic virus type L in wild Ethiopian baboons

Takemura, T., Yamashita, M., Shimada, M. K., Ohkura, S., Shotake, T., Ikeda, M., Miura, T. & Hayami, M., 05-02-2002, In : Journal of Virology. 76, 4, p. 1642-1648 7 p.

Research output: Contribution to journalArticle

Simian T-lymphotropic virus 3
T-Cell Leukemia
Papio
leukemia
T-lymphocytes
22 Citations (Scopus)

HMGA1a: Sequence-specific RNA-binding factor causing sporadic Alzheimer's disease-linked exon skipping of presenilin-2 pre-mRNA

Manabe, T., Ohe, K., Katayama, T., Matsuzaki, S., Yanagita, T., Okuda, H., Bando, Y., Imaizumi, K., Reeves, R., Tohyama, M. & Mayeda, A., 01-10-2007, In : Genes to Cells. 12, 10, p. 1179-1191 13 p.

Research output: Contribution to journalArticle

Presenilin-2
High Mobility Group Proteins
RNA Precursors
Exons
Alzheimer Disease
5 Citations (Scopus)

HMGA1a induces alternative splicing of estrogen receptor alpha in MCF-7 human breast cancer cells

Ohe, K., Miyajima, S., Abe, I., Tanaka, T., Hamaguchi, Y., Harada, Y., Horita, Y., Beppu, Y., Ito, F., Yamasaki, T., Terai, H., Mori, M., Murata, Y., Tanabe, M., Ashida, K., Kobayashi, K., Enjoji, M., Yanase, T., Harada, N., Utsumi, T. & 1 others, Mayeda, A., 09-2018, In : Journal of Steroid Biochemistry and Molecular Biology. 182, p. 21-26 6 p.

Research output: Contribution to journalArticle

High Mobility Group Proteins
Estrogen Receptor alpha
Alternative Splicing
Cells
Breast Neoplasms
2 Citations (Scopus)

HMGA1a induces alternative splicing of the estrogen receptor-alpha gene by trapping U1 snRNP to an upstream pseudo-5' splice site

Ohe, K., Miyajima, S., Tanaka, T., Hamaguchi, Y., Harada, Y., Horita, Y., Beppu, Y., Ito, F., Yamasaki, T., Terai, H., Mori, M., Murata, Y., Tanabe, M., Abe, I., Ashida, K., Kobayashi, K., Enjoji, M., Nomiyama, T., Yanase, T., Harada, N. & 2 others, Utsumi, T. & Mayeda, A., 08-06-2018, In : Frontiers in Molecular Biosciences. 5, JUN, 52.

Research output: Contribution to journalArticle

U1 Small Nuclear Ribonucleoproteins
High Mobility Group Proteins
RNA Splice Sites
Estrogen Receptor alpha
Alternative Splicing
23 Citations (Scopus)
U1 Small Nuclear Ribonucleoproteins
Small Nuclear Ribonucleoproteins
High Mobility Group Proteins
RNA Splice Sites
Exons
215 Citations (Scopus)

hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing

Caputi, M., Mayeda, A., Krainer, A. R. & Zahler, A. M., 15-07-1999, In : EMBO Journal. 18, 14, p. 4060-4067 8 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein Group A-B
RNA Precursors
Viruses
HIV-1
Exons
21 Citations (Scopus)

HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA

Rahman, M. A., Masuda, A., Ohe, K., Ito, M., Hutchinson, D. O., Mayeda, A., Engel, A. G. & Ohno, K., 25-10-2013, In : Scientific reports. 3, 2931.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein L
RNA Precursors
Exons
Heterogeneous-Nuclear Ribonucleoproteins
RNA-Binding Proteins
50 Citations (Scopus)

Human Immunodeficiency Virus Type 1 hnRNP A/B-Dependent Exonic Splicing Silencer ESSV Antagonizes Binding of U2AF65 to Viral Polypyrimidine Tracts

Domsic, J. K., Wang, Y., Mayeda, A., Krainer, A. R. & Stoltzfus, C. M., 01-12-2003, In : Molecular and Cellular Biology. 23, 23, p. 8762-8772 11 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoproteins
RNA Splice Sites
HIV-1
Heterogeneous-Nuclear Ribonucleoprotein Group A-B
U1 Small Nuclear Ribonucleoproteins
73 Citations (Scopus)

Human RNPS1 and Its Associated Factors: A Versatile Alternative Pre-mRNA Splicing Regulator in Vivo

Sakashita, E., Tatsumi, S., Werner, D., Endo, H. & Mayeda, A., 01-02-2004, In : Molecular and Cellular Biology. 24, 3, p. 1174-1187 14 p.

Research output: Contribution to journalArticle

RNA Precursors
Exons
Serine
U1 Small Nuclear Ribonucleoproteins
Proteins
6 Citations (Scopus)

Identification and validation of evolutionarily conserved unusually short pre-mRNA introns in the human genome

Shimada, M. K., Sasaki-Haraguchi, N. & Mayeda, A., 07-05-2015, In : International journal of molecular sciences. 16, 5, p. 10376-10388 13 p.

Research output: Contribution to journalArticle

genome
RNA Precursors
nucleotides
Human Genome
Nucleotides
32 Citations (Scopus)

Identification of a neuronal cell surface molecule, plexin, in mice

Kameyama, T., Murakami, Y., Suto, F., Kawakami, A., Takagi, S., Hirata, T. & Fujisawa, H., 13-09-1996, In : Biochemical and Biophysical Research Communications. 226, 2, p. 524-529 6 p.

Research output: Contribution to journalArticle

Molecules
Xenopus
Cysteine
Proteins
Proto-Oncogene Proteins c-met
10 Citations (Scopus)

Identification of a novel component C2ORF3 in the lariat-intron complex: Lack of C2ORF3 interferes with pre-mRNA splicing via intron turnover pathway

Yoshimoto, R., Okawa, K., Yoshida, M., Ohno, M. & Kataoka, N., 01-01-2014, In : Genes to Cells. 19, 1, p. 78-87 10 p.

Research output: Contribution to journalArticle

RNA Precursors
Introns
Proteins
Immunoprecipitation
Mass Spectrometry
107 Citations (Scopus)

Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles

Miyagawa, R., Tano, K., Mizuno, R. I. E., Nakamura, Y. O., Ijiri, K., Rakwal, R., Shibato, J., Masuo, Y., Mayeda, A., Hirose, T. & Akimitsu, N., 01-04-2012, In : RNA. 18, 4, p. 738-751 14 p.

Research output: Contribution to journalArticle

Untranslated RNA
Trans-Activators
Gene Expression
Messenger RNA
Gene Expression Regulation