Research Output

  • 5793 Citations
  • 37 h-Index
  • 213 Article
  • 11 Letter
  • 8 Review article
  • 2 Comment/debate
2010

Rituximab

Kinoshita, T. & Tomita, A., 01-01-2010, In : Biotherapy. 24, 1, p. 67-70 4 p.

Research output: Contribution to journalArticle

Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens

Warren, E. H., Fujii, N., Akatsuka, Y., Chaney, C. N., Mito, J. K., Loeb, K. R., Gooley, T. A., Brown, M. L., Koo, K. K. W., Rosinski, K. V., Ogawa, S., Matsubara, A., Appelbaum, F. R. & Riddell, S. R., 13-05-2010, In : Blood. 115, 19, p. 3869-3878 10 p.

Research output: Contribution to journalArticle

167 Citations (Scopus)
2009

Comparative clinicopathological study of primary CNS diffuse large B-cell lymphoma and intravascular large B-cell lymphoma

Imai, H., Shimada, K., Shimada, S., Abe, M., Okamoto, M., Kitamura, K., Kinoshita, T., Shiraishi, T. & Nakamura, S., 01-07-2009, In : Pathology International. 59, 7, p. 431-437 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Down-regulation of CD20 expression in B-cell lymphoma cells after treatment with rituximab-containing combination chemotherapies: Its prevalence and clinical significance

Hiraga, J., Tomita, A., Sugimoto, T., Shimada, K., Ito, M., Nakamura, S., Kiyoi, H., Kinoshita, T. & Naoe, T., 19-11-2009, In : Blood. 113, 20, p. 4885-4893 9 p.

Research output: Contribution to journalArticle

142 Citations (Scopus)

Escape mechanisms from antibody therapy to lymphoma cells: Downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation

Sugimoto, T., Tomita, A., Hiraga, J., Shimada, K., Kiyoi, H., Kinoshita, T. & Naoe, T., 04-12-2009, In : Biochemical and Biophysical Research Communications. 390, 1, p. 48-53 6 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Exploration of the Genetic Basis of GVHD by Genetic Association Studies

Ogawa, S., Matsubara, A., Onizuka, M., Kashiwase, K., Sanada, M., Kato, M., Nannya, Y., Akatsuka, Y., Satake, M., Takita, J., Chiba, S., Saji, H., Maruya, E., Inoko, H., Morishima, Y., Kodera, Y. & Takehiko, S., 01-01-2009, In : Biology of Blood and Marrow Transplantation. 15, 1 SUPPL., p. 39-41 3 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Factor VII deficiency: A double heterozygote of an Arg402Stop with a deletion of the C-terminal five amino acids and a Thr359Met

Okamoto, M., Katsuda, I., Ohshika, Y., Maruyama, F., Ezaki, K., Emi, N. & Ichihara, Y., 01-05-2009, In : European Journal of Haematology. 82, 5, p. 405-407 3 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)

Frequent inactivation of A20 in B-cell lymphomas

Kato, M., Sanada, M., Kato, I., Sato, Y., Takita, J., Takeuchi, K., Niwa, A., Chen, Y., Nakazaki, K., Nomoto, J., Asakura, Y., Muto, S., Tamura, A., Iio, M., Akatsuka, Y., Hayashi, Y., Mori, H., Igarashi, T., Kurokawa, M., Chiba, S. & 9 others, Mori, S., Ishikawa, Y., Okamoto, K., Tobinai, K., Nakagama, H., Nakahata, T., Yoshino, T., Kobayashi, Y. & Ogawa, S., 04-06-2009, In : Nature. 459, 7247, p. 712-716 5 p.

Research output: Contribution to journalArticle

403 Citations (Scopus)

Successful pregnancy in a patient with chronic myeloid leukemia under treatment with imatinib

Tsuzuki, M., Inaguma, Y., Handa, K., Hasegawa, A., Yamamoto, Y., Watanabe, M., Mizuta, S., Maruyama, F., Okamoto, M. & Emi, N., 05-10-2009, In : Internal Medicine. 48, 16, p. 1433-1435 3 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Thrombotic thrombocytopenic purpura with mixed connective tissue disease. A case report

Kajita, N., Muro, Y., Tomita, A., Hirashima, K., Matsushita, T., Naoe, T. & Tomita, Y., 27-07-2009, In : Japanese Journal of Allergology. 58, 5, p. 567-572 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2008

Abnormal cytoplasmic dyslocalisation and/or reduction of nucleophosmin protein level rarely occurs in myelodysplastic syndromes

Ishikawa, Y., Xu, J., Sakashita, G., Urano, T., Suzuki, T., Tomita, A., Kiyoi, H., Nakamura, S. & Naoe, T., 16-12-2008, In : Leukemia and Lymphoma. 49, 12, p. 2359-2364 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Antigen-specific allogeneic immunotherapy--selective augmentation of GVL effects

Akatsuka, Y., 05-2008, In : Gan to kagaku ryoho. Cancer & chemotherapy. 35, 5, p. 713-719 7 p.

Research output: Contribution to journalReview article

CD16+ CD56- NK cells in the peripheral blood of cord blood transplant recipients: A unique subset of NK cells possibly associated with graft-versus-leukemia effect

Lu, X., Kondo, Y., Takamatsu, H., Ohata, K., Yamazaki, H., Takami, A., Akatsuka, Y. & Nakao, S., 01-07-2008, In : European Journal of Haematology. 81, 1, p. 18-25 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Chronic myeloid leukemia following chemotherapy with 5′-deoxy-5-fluorouridine for gastric cancer

Tsuzuki, M., Handa, K., Yamamoto, K., Hasegawa, A., Yamamoto, Y., Watanabe, M., Mizuta, S., Maruyama, F., Okamoto, M., Emi, N. & Ezaki, K., 24-11-2008, In : Internal Medicine. 47, 19, p. 1739-1741 3 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Clinical significance of nuclear non-phosphorylated beta-catenin in acute myeloid leukaemia and myelodysplastic syndrome

Xu, J., Suzuki, M., Niwa, Y., Hiraga, J., Nagasaka, T., Ito, M., Nakamura, S., Tomita, A., Abe, A., Kiyoi, H., Kinoshita, T. & Naoe, T., 01-02-2008, In : British Journal of Haematology. 140, 4, p. 394-401 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

De novo CD5+ diffuse large B-cell lymphoma: Results of a detailed clinicopathological review in 120 patients

Yamaguchi, M., Nakamura, N., Suzuki, R., Kagami, Y., Okamoto, M., Ichinohasama, R., Yoshino, T., Suzumiya, J., Murase, T., Miura, I., Ohshima, K., Nishikori, M., Tamaru, J. I., Taniwaki, M., Hirano, M., Morishima, Y., Ueda, R., Shiku, H. & Nakamura, S., 01-08-2008, In : Haematologica. 93, 8, p. 1195-1202 8 p.

Research output: Contribution to journalArticle

Open Access
85 Citations (Scopus)

Identification of a human leukocyte antigen-A24-restricted T-cell epitope derived from interleukin-13 receptor α2 chain, a glioma-associated antigen: Laboratory investigation

Shimato, S., Natsume, A., Wakabayashi, T., Tsujimura, K., Nakahara, N., Ishii, J., Ito, M., Akatsuka, Y., Kuzushima, K. & Yoshida, J., 01-07-2008, In : Journal of Neurosurgery. 109, 1, p. 117-122 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Possibility of selective induction of a GVL effect without increasing GVHD

Akatsuka, Y., 01-08-2008, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 49, 8, p. 607-615 9 p.

Research output: Contribution to journalReview article

Retrospective analysis of intravascular large B-cell lymphoma treated with rituximab-containing chemotherapy as reported by the IVL Study Group in Japan

Shimada, K., Matsue, K., Yamamoto, K., Murase, T., Ichikawa, N., Okamoto, M., Niitsu, N., Kosugi, H., Tsukamoto, N., Miwa, H., Asaoku, H., Kikuchi, A., Matsumoto, M., Saburi, Y., Masaki, Y., Yamaguchi, M., Nakamura, S., Naoe, T. & Kinoshita, T., 15-09-2008, In : Journal of Clinical Oncology. 26, 19, p. 3189-3195 7 p.

Research output: Contribution to journalArticle

163 Citations (Scopus)
2007

Adult T-cell lymphoma/leukemia with angioimmunoblastic T-cell lymphomalike features: Report of 11 cases

Karube, K., Suzumiya, J., Okamoto, M., Takeshita, M., Maeda, K., Sakaguchi, M., Inada, T., Tsushima, H., Kikuchi, M. & Ohshima, K., 01-02-2007, In : American Journal of Surgical Pathology. 31, 2, p. 216-223 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

CDH1 is a specific marker for undifferentiated spermatogonia in mouse testes

Tokuda, M., Kadokawa, Y., Kurahashi, H. & Marunouchi, T., 01-01-2007, In : Biology of Reproduction. 76, 1, p. 130-141 12 p.

Research output: Contribution to journalArticle

172 Citations (Scopus)

Differential diagnosis of malignant lymphoma

Yamashita, T. & Okamoto, M., 28-01-2007, In : Nippon rinsho. Japanese journal of clinical medicine. 65 Suppl 1, p. 342-345 4 p.

Research output: Contribution to journalReview article

Effects of HLA Allele and Killer Immunoglobulin-Like Receptor Ligand Matching on Clinical Outcome in Leukemia Patients Undergoing Transplantation With T-cell-Replete Marrow From an Unrelated Donor

Morishima, Y., Yabe, T., Matsuo, K., Kashiwase, K., Inoko, H., Saji, H., Yamamoto, K., Maruya, E., Akatsuka, Y., Onizuka, M., Sakamaki, H., Sao, H., Ogawa, S., Kato, S., Juji, T., Sasazuki, T. & Kodera, Y., 01-03-2007, In : Biology of Blood and Marrow Transplantation. 13, 3, p. 315-328 14 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Epigenetic regulation of CD20 protein expression in a novel B-cell lymphoma cell line, RRBL1, established from a patient treated repeatedly with rituximab-containing chemotherapy

Tomita, A., Hiraga, J., Kiyoi, H., Ninomiya, M., Sugimoto, T., Ito, M., Kinoshita, T. & Naoe, T., 01-07-2007, In : International Journal of Hematology. 86, 1, p. 49-57 9 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Full-length EBNA1 mRNA-transduced dendritic cells stimulate cytotoxic T lymphocytes recognizing a novel HLA-Cw*0303- and -Cw*0304-restricted epitope on EBNA1-expressing cells

Ito, Y., Demachi-Okamura, A., Ohta, R., Akatsuka, Y., Nishida, K., Tsujimura, K., Morishima, Y., Takahashi, T. & Kuzushima, K., 01-03-2007, In : Journal of General Virology. 88, 3, p. 770-780 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Intravascular large B-cell lymphoma (IVLBCL): A clinicopathologic study of 96 cases with special reference to the immunophenotypic heterogeneity of CD5

Murase, T., Yamaguchi, M., Suzuki, R., Okamoto, M., Sato, Y., Tamaru, J. I., Kojima, M., Miura, I., Mori, N., Yoshino, T. & Nakamura, S., 15-01-2007, In : Blood. 109, 2, p. 478-485 8 p.

Research output: Contribution to journalArticle

257 Citations (Scopus)

Minor histocompatibility antigens as targets for immunotherapy using allogeneic immune reactions

Akatsuka, Y., Morishima, Y., Kuzushima, K., Kodera, Y. & Takahashi, T., 01-08-2007, In : Cancer science. 98, 8, p. 1139-1146 8 p.

Research output: Contribution to journalReview article

31 Citations (Scopus)

Phase II study of chemotherapy and stem cell transplantation for adult acute lymphoblastic leukemia or lymphoblastic lymphoma: Japan Clinical Oncology Group study 9004

Tobinai, K., Takeyama, K., Arima, F., Aikawa, K., Kobayashi, T., Hanada, S., Kasai, M., Ogura, M., Sueoka, E., Mukai, K., Tajima, K., Fukuda, H., Shirakawa, S., Hotta, T., Shimoyama, M., Mikuni, C., AIkawa, K., Kasai, M., Kiyama, Y., Miura, I. & 56 others, Miura, A., Sai, T., Sasaki, Y., Itoh, K., Shimoyama, M., Tobinai, K., Minato, K., Takenaka, T., Takeyama, K., Kohno, A., Sawada, U., Aoki, I., Kawano, K., Ibuka, T., Miwa, T., Togawa, A., Yamada, H., Iwase, S., Deura, K., Seki, S., Ogura, M., Kagami, Y., Suzuki, H., Nagai, H., Hotta, T., Kinoshita, T., Hirano, M., Okamoto, M., Shirakawa, S., Kobayashi, T., Masuya, M., Yamaguchi, M., Konda, S., Masaki, Y., Susuki, T., Fukuhara, S., Ohno, H., Abe, T., Taniwaki, M., Ohno, Y., Irino, S., Nagai, M., Uike, N., Okamoto, S., Fujita, K., Izumi, Y., Shimamoto, Y., Fukushima, H., Yamaguchi, K., Takatsuki, K., Matsumoto, M., Hanada, S., Uozumi, K., Utsunomiya, A., Araki, K. & Ohshiro, I., 01-09-2007, In : Cancer science. 98, 9, p. 1350-1357 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Principal and perspective of adoptive immuno-cell therapy for hematological malignancies

Akatsuka, Y., 01-10-2007, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 48, 10, p. 1328-1338 11 p.

Research output: Contribution to journalReview article

Successful second cord blood transplantation using fludarabine and cyclophosphamide as a preparative regimen for graft rejection following reduced-intensity cord blood transplantation [2]

Mizutani, E., Narimatsu, H., Murata, M., Tomita, A., Kiyoi, H. & Naoe, T., 01-07-2007, In : Bone Marrow Transplantation. 40, 1, p. 85-87 3 p.

Research output: Contribution to journalLetter

9 Citations (Scopus)

The HLA-A *0201-restricted minor histocompatibility antigen HA-1H peptide can also be presented by another HLA-A2 subtype, A *0206

Torikai, H., Akatsuka, Y., Miyauchi, H., Terakura, S., Onizuka, M., Tsujimura, K., Miyamura, K., Morishima, Y., Kodera, Y., Kuzushima, K. & Takahashi, T., 01-07-2007, In : Bone Marrow Transplantation. 40, 2, p. 165-174 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2006

Bone marrow may be a reservoir of long-lived memory T cells specific for minor histocompatibility antigen [4]

Akatsuka, Y., Torikai, H., Inamoto, Y., Tsujimura, K., Morishima, Y., Kodera, Y., Kuzushima, K. & Takahashi, T., 01-11-2006, In : British Journal of Haematology. 135, 3, p. 413-414 2 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

Characterization of murine CD160+ CD8+ T lymphocytes

Tsujimura, K., Obata, Y., Matsudaira, Y., Nishida, K., Akatsuka, Y., Ito, Y., Demachi-Okamura, A., Kuzushima, K. & Takahashi, T., 15-07-2006, In : Immunology Letters. 106, 1, p. 48-56 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Epstein-Barr virus (EBV) latent membrane protein-1-specific cytotoxic T lymphocytes targeting EBV-carrying natural killer cell malignancies

Demachi-Okamura, A., Ito, Y., Akatsuka, Y., Tsujimura, K., Morishima, Y., Takahashi, T. & Kuzushima, K., 01-03-2006, In : European Journal of Immunology. 36, 3, p. 593-602 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Expression profiling analysis of the CD5+ diffuse large B-cell lymphoma subgroup: Development of a CD5 signature

Suguro, M., Tagawa, H., Kagami, Y., Okamoto, M., Ohshima, K., Shiku, H., Morishima, Y., Nakamura, S. & Seto, M., 01-09-2006, In : Cancer science. 97, 9, p. 868-874 7 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Generation of peptide-specific CD8+ T cells by phytohemagglutinin-stimulated antigen-mRNA-transduced CD4+ T cells

Naota, H., Miyahara, Y., Okumura, S., Kuzushima, K., Akatsuka, Y., Hiasa, A., Kitano, S., Takahashi, T., Yuta, A., Majima, Y. & Shiku, H., 31-07-2006, In : Journal of Immunological Methods. 314, 1-2, p. 54-66 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
36 Citations (Scopus)

Immunoglobulin VH genes in thymic MALT lymphoma are biased toward a restricted repertoire and are frequently unmutated

Yoshida, M., Okabe, M., Eimoto, T., Shimizu, S., Ueda-Otsuka, K., Okamoto, M., Ishii, G., Ueda, R., Chan, J. K. C., Nakamura, S. & Inagaki, H., 01-02-2006, In : Journal of Pathology. 208, 3, p. 415-422 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Role of minor histocompatibility antigens in hematopoietic cell transplantation

Akatsuka, Y., 01-10-2006, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 47, 10, p. 1353-1363 11 p.

Research output: Contribution to journalReview article

Successful Hemostasis after Dental Extraction with the Use of Recombinant Activated Factor VII in a Factor VII Deficient Patient

Satoh, K., Okamoto, M., Torimura, A., Taguchi, R., Mineno, Y. & Mizutani, H., 01-01-2006, In : Oral Science International. 3, 1, p. 10-12 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2005

Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia

Suzuki, T., Kiyoi, H., Ozeki, K., Tomita, A., Yamaji, S., Suzuki, R., Kodera, Y., Miyawaki, S., Asou, N., Kuriyama, K., Yagasaki, F., Shimazaki, C., Akiyama, H., Nishimura, M., Motoji, T., Shinagawa, K., Takeshita, A., Ueda, R., Kinoshita, T., Emi, N. & 1 others, Naoe, T., 01-10-2005, In : Blood. 106, 8, p. 2854-2861 8 p.

Research output: Contribution to journalArticle

200 Citations (Scopus)

Comparison of genome profiles for identification of distinct subgroups of diffuse large B-cell lymphoma

Tagawa, H., Suguro, M., Tsuzuki, S., Matsuo, K., Karnan, S., Ohshima, K., Okamoto, M., Morishima, Y., Nakamura, S. & Seto, M., 01-09-2005, In : Blood. 106, 5, p. 1770-1777 8 p.

Research output: Contribution to journalArticle

178 Citations (Scopus)

Cytogenetic features of de novo CD5-positive diffuse large B-cell lymphoma: Chromosome aberrations affecting 8p21 and 11q13 constitute major subgroups with different overall survival

Yoshioka, T., Miura, I., Kume, M., Takahashi, N., Okamoto, M., Ichinohasama, R., Yoshino, T., Yamaguchi, M., Hirokawa, M., Sawada, K. I. & Nakamura, S., 01-02-2005, In : Genes Chromosomes and Cancer. 42, 2, p. 149-157 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Retroviral vector backbone immunogenicity: Identification of cytotoxic T-cell epitopes in retroviral vector-packaging sequences

Kondo, E., Akatsuka, Y., Nawa, A., Kuzushima, K., Tsujimura, K., Tanimoto, M., Kodera, Y., Morishima, Y., Kuzuya, K. & Takahashi, T., 01-02-2005, In : Gene therapy. 12, 3, p. 252-258 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2004

Analysis of Chromosomal Imbalances in de novo CD5-Positive Diffuse Large-B-cell Lymphoma Detected by Comparative Genomic Hybridization

Karnan, S., Tagawa, H., Suzuki, R., Suguro, M., Yamaguchi, M., Okamoto, M., Morishima, Y., Nakamura, S. & Seto, M., 01-01-2004, In : Genes Chromosomes and Cancer. 39, 1, p. 77-81 5 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Clinical Significance of Intracytoplasmic nm23-H1 Expression in Diffuse Large B-Cell Lymphoma

Niitsu, N., Nakamine, H., Okamoto, M., Akamatsu, H., Higashihara, M., Honma, Y., Okabe-Kado, J. & Hirano, M., 01-04-2004, In : Clinical Cancer Research. 10, 7, p. 2482-2490 9 p.

Research output: Contribution to journalArticle

Open Access
28 Citations (Scopus)

Genome-wide array-based comparative genomic hybridization of diffuse large B-cell lymphoma: Comparison between CD5-positive and CD5-negative cases

Tagawa, H., Tsuzuki, S., Suzuki, R., Karnan, S., Ota, A., Kameoka, Y., Suguro, M., Matsuo, K., Yamaguchi, M., Okamoto, M., Morishima, Y., Nakamura, S. & Seto, M., 01-09-2004, In : Cancer Research. 64, 17, p. 5948-5955 8 p.

Research output: Contribution to journalArticle

Open Access
62 Citations (Scopus)

Identification of an epitope from the epithelial cell adhesion molecule eliciting HLA-A*2402-restricted cytotoxic T-lymphocyte responses

Tajima, K., Demachi, A., Ito, Y., Nishida, K., Akatsuka, Y., Tsujimura, K., Kuwano, H., Mitsudomi, T., Takahashi, T. & Kuzushima, K., 01-12-2004, In : Tissue Antigens. 64, 6, p. 650-659 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Immunity against mouse thymus-leukemia antigen (TL) protects against development of lymphomas induced by a chemical carcinogen, N-butyl-N-nitrosourea

Tsujimura, K., Obata, Y., Matsudaira, Y., Ozeki, S., Taguchi, O., Nishida, K., Okanami, Y., Akatsuka, Y., Kuzushima, K. & Takahashi, T., 01-11-2004, In : Cancer science. 95, 11, p. 914-919 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Interferon-γ differentially regulates susceptibility of lung cancer cells to telomerase-specific cytotoxic T lymphocytes

Tajima, K., Ito, Y., Demachi, A., Nishida, K., Akatsuka, Y., Tsujimura, K., Hida, T., Morishima, Y., Kuwano, H., Mitsudomi, T., Takahashi, T. & Kuzushima, K., 20-06-2004, In : International Journal of Cancer. 110, 3, p. 403-412 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)