Research Output

2020

Acceptance of the deltoid muscle injection of aripiprazole long-acting injectable in the patients with schizophrenia

Kamei, H., Homma, Y., Takeuchi, I., Hajitsu, G., Tozawa, K., Hatano, M., Fukui, A., Hanya, M., Yamada, S. & Iwata, N., 01-01-2020, In : Clinical Psychopharmacology and Neuroscience. 18, 1, p. 49-57 9 p.

Research output: Contribution to journalArticle

Open Access

A double-blind, randomized, placebo-controlled trial of adjunctive blue-blocking glasses for the treatment of sleep and circadian rhythm in patients with bipolar disorder

Esaki, Y., Takeuchi, I., Tsuboi, S., Fujita, K., Iwata, N. & Kitajima, T., 01-01-2020, (Accepted/In press) In : Bipolar Disorders.

Research output: Contribution to journalArticle

Aripiprazole vs. brexpiprazole for acute schizophrenia: a systematic review and network meta-analysis

Kishi, T., Ikuta, T., Matsuda, Y., Sakuma, K. & Iwata, N., 01-05-2020, In : Psychopharmacology. 237, 5, p. 1459-1470 12 p.

Research output: Contribution to journalArticle

Association between light exposure at night and manic symptoms in bipolar disorder: cross-sectional analysis of the APPLE cohort

Esaki, Y., Obayashi, K., Saeki, K., Fujita, K., Iwata, N. & Kitajima, T., 01-01-2020, (Accepted/In press) In : Chronobiology International.

Research output: Contribution to journalArticle

Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region with Cortical and Subcortical Morphology and Cognition

Van Der Meer, D., Sønderby, I. E., Kaufmann, T., Walters, G. B., Abdellaoui, A., Ames, D., Amunts, K., Andersson, M., Armstrong, N. J., Bernard, M., Blackburn, N. B., Blangero, J., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Bülow, R., Cahn, W., Calhoun, V. D., Caspers, S., Cavalleri, G. L. & 112 others, Ching, C. R. K., Cichon, S., Ciufolini, S., Corvin, A., Crespo-Facorro, B., Curran, J. E., Dalvie, S., Dazzan, P., De Geus, E. J. C., De Zubicaray, G. I., De Zwarte, S. M. C., Delanty, N., Den Braber, A., Desrivieres, S., Di Forti, M., Doherty, J. L., Donohoe, G., Ehrlich, S., Eising, E., Espeseth, T., Fisher, S. E., Fladby, T., Frei, O., Frouin, V., Fukunaga, M., Gareau, T., Glahn, D. C., Grabe, H. J., Groenewold, N. A., Gústafsson, Ó., Haavik, J., Haberg, A. K., Hashimoto, R., Hehir-Kwa, J. Y., Hibar, D. P., Hillegers, M. H. J., Hoffmann, P., Holleran, L., Hottenga, J. J., Hulshoff Pol, H. E., Ikeda, M., Jacquemont, S., Jahanshad, N., Jockwitz, C., Johansson, S., Jönsson, E. G., Kikuchi, M., Knowles, E. E. M., Kwok, J. B., Le Hellard, S., Linden, D. E. J., Liu, J., Lundervold, A., Lundervold, A. J., Martin, N. G., Mather, K. A., Mathias, S. R., McMahon, K. L., McRae, A. F., Medland, S. E., Moberget, T., Moreau, C., Morris, D. W., Mühleisen, T. W., Murray, R. M., Nordvik, J. E., Nyberg, L., Olde Loohuis, L. M., Ophoff, R. A., Owen, M. J., Paus, T., Pausova, Z., Peralta, J. M., Pike, B., Prieto, C., Quinlan, E. B., Reinbold, C. S., Reis Marques, T., Rucker, J. J. H., Sachdev, P. S., Sando, S. B., Schofield, P. R., Schork, A. J., Schumann, G., Shin, J., Shumskaya, E., Silva, A. I., Sisodiya, S. M., Steen, V. M., Stein, D. J., Strike, L. T., Tamnes, C. K., Teumer, A., Thalamuthu, A., Tordesillas-Gutiérrez, D., Uhlmann, A., Úlfarsson, M., Van 'T Ent, D., Van Den Bree, M. B. M., Vassos, E., Wen, W., Wittfeld, K., Wright, M. J., Zayats, T., Dale, A. M., Djurovic, S., Agartz, I., Westlye, L. T., Stefánsson, H., Stefánsson, K., Thompson, P. M. & Andreassen, O. A., 04-2020, In : JAMA Psychiatry. 77, 4, p. 420-430 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Autonomic nervous activity of patient with schizophrenia during Pepper CPGE-led upper limb range of motion exercises

Tanioka, R., Yasuhara, Y., Osaka, K., Kai, Y., Zhao, Y., Tanioka, T., Takase, K., Dino, M. J. S. & Locsin, R. C., 02-2020, In : Enfermeria clinica. 30, p. 48-53 6 p.

Research output: Contribution to journalArticle

Blonanserin patch vsOther Antipsychotics for Acute Schizophrenia: A Systematic Review of Double-blind, Randomized, Placebo-controlled, Phase 3 Trials in Japan

Kishi, T., Yoshimura, R., Matsuda, Y., Sakuma, K. & Iwata, N., 01-05-2020, In : Pharmacopsychiatry. 53, 3, p. 122-132 11 p.

Research output: Contribution to journalReview article

Open Access

Development of a knee joint assist suit with a velocity-based mechanical safety device: Control method and experiments

Ikeda, K., Kaneda, T., Kai, Y., Sugawara, K., Tanioka, T., Tomizuka, M., Zhao, Y., Takase, K. & Dino, M. J. S., 01-02-2020, In : Enfermeria clinica. 30, p. 23-26 4 p.

Research output: Contribution to journalArticle

Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia

for the 16p11.2 European Consortium, for the ENIGMA-CNV working group, 01-03-2020, In : Molecular Psychiatry. 25, 3, p. 584-602 19 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Efficacy and safety of blonanserin transdermal patch in patients with schizophrenia: A 6-week randomized, double-blind, placebo-controlled, multicenter study

Iwata, N., Ishigooka, J., Kim, W. H., Yoon, B. H., Lin, S. K., Sulaiman, A. H., Cosca, R., Wang, L., Suchkov, Y., Agarkov, A., Watabe, K., Matsui, T., Sato, T., Inoue, Y., Higuchi, T., Correll, C. U. & Kane, J. M., 01-2020, In : Schizophrenia Research. 215, p. 408-415 8 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Efficacy and Safety of Psychostimulants for Alzheimer's Disease: A Systematic Review and Meta-Analysis

Kishi, T., Sakuma, K. & Iwata, N., 01-05-2020, In : Pharmacopsychiatry. 53, 3, p. 109-114 6 p.

Research output: Contribution to journalReview article

Evaluation of the Remote-controlled Drone System using an Eye-tracking device through the Internet for patients in bedridden conditions

Kai, Y., Munir, H. M. U., Onda, M., Adachi, Y., Hayama, J., Zhao, Y., Tanioka, T., Locsin, R., Takase, K. & Dino, M. J. S., 02-2020, In : Enfermeria Clinica. 30, p. 18-22 5 p.

Research output: Contribution to journalArticle

Global DNA hypomethylation and its correlation to the betaine level in peripheral blood of patients with schizophrenia

Murata, Y., Ikegame, T., Koike, S., Saito, T., Ikeda, M., Sasaki, T., Iwata, N., Kasai, K., Bundo, M. & Iwamoto, K., 20-04-2020, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 99, 109855.

Research output: Contribution to journalArticle

GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits

Matoba, N., Akiyama, M., Ishigaki, K., Kanai, M., Takahashi, A., Momozawa, Y., Ikegawa, S., Ikeda, M., Iwata, N., Hirata, M., Matsuda, K., Murakami, Y., Kubo, M., Kamatani, Y. & Okada, Y., 01-03-2020, In : Nature Human Behaviour. 4, 3, p. 308-316 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Human leukocyte antigen DRB1*04:05 and clozapine-induced agranulocytosis/granulocytopenia

Clozapine Pharmacogenomics Consortium of Japan (CPC-J), 01-05-2020, In : Australian and New Zealand Journal of Psychiatry. 54, 5, p. 545-546 2 p.

Research output: Contribution to journalLetter

Lemborexant vs suvorexant for insomnia: A systematic review and network meta-analysis

Kishi, T., Nomura, I., Matsuda, Y., Sakuma, K., Okuya, M., Ikuta, T. & Iwata, N., 09-2020, In : Journal of Psychiatric Research. 128, p. 68-74 7 p.

Research output: Contribution to journalArticle

Long-Term Safety and Efficacy of Blonanserin Transdermal Patches in Japanese Patients with Schizophrenia: A 52-Week Open-Label, Multicenter Study

Iwata, N., Ishigooka, J., Naoi, I., Matsumoto, M., Kanamori, Y., Nakamura, H. & Higuchi, T., 01-01-2020, In : CNS Drugs. 34, 1, p. 103-116 14 p.

Research output: Contribution to journalArticle

Open Access

Polygenic risk scores in schizophrenia with clinically significant copy number variants

Taniguchi, S., Ninomiya, K., Kushima, I., Saito, T., Shimasaki, A., Sakusabe, T., Momozawa, Y., Kubo, M., Kamatani, Y., Ozaki, N., Ikeda, M. & Iwata, N., 01-01-2020, In : Psychiatry and clinical neurosciences. 74, 1, p. 35-39 5 p.

Research output: Contribution to journalArticle

Open Access

Rehabilitation care with Pepper humanoid robot: A qualitative case study of older patients with schizophrenia and/or dementia in Japan

Sato, M., Yasuhara, Y., Osaka, K., Ito, H., Dino, M. J. S., Ong, I. L., Zhao, Y. & Tanioka, T., 02-2020, In : Enfermeria Clinica. 30, p. 32-36 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Treatment Persistence Between Long-Acting Injectable Versus Orally Administered Aripiprazole Among Patients with Schizophrenia in a Real-World Clinical Setting in Japan

Iwata, N., Inagaki, A., Sano, H., Niidome, K., Kojima, Y. & Yamada, S., 01-07-2020, In : Advances in Therapy. 37, 7, p. 3324-3336 13 p.

Research output: Contribution to journalArticle

Open Access

Utility of the sleep stage sequence preceding sleep onset REM periods for the diagnosis of narcolepsy: a study in a Japanese cohort

Kawai, R., Watanabe, A., Fujita, S., Hirose, M., Esaki, Y., Arakawa, C., Iwata, N. & Kitajima, T., 04-2020, In : Sleep Medicine. 68, p. 9-17 9 p.

Research output: Contribution to journalArticle

Vortioxetine vs placebo in major depressive disorder: A systematic review and meta-analysis of double-blind, randomized, placebo-controlled, phase 3 trials in Japan

Kishi, T., Sakuma, K., Okuya, M., Matsuda, Y. & Iwata, N., 01-05-2020, In : Psychiatry and clinical neurosciences. 74, 5, p. 330-332 3 p.

Research output: Contribution to journalLetter

2019

A polygenic resilience score moderates the genetic risk for schizophrenia

The Schizophrenia Working Group of the Psychiatric Genomics Consortium & Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), 01-01-2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

A reflective journey of caring: A case study between a patient with schizophrenia and the interdisciplinary team

Zhao, Y., Osaka, K., Yasuhara, Y., King, B. & Tanioka, T., 01-01-2019, In : Journal of Medical Investigation. 66, 1.2, p. 15-18 4 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

A single medical marker for diagnosis of methamphetamine addiction-dna methylation of SHATI/NAT8L promoter sites from patient blood

Yuka, K., Nishizawa, D., Hasegawa, J., Uno, K., Miyanishi, H., Ujike, H., Ozaki, N., Inada, T., Iwata, N., Sora, I., Iyo, M., Yamada, M., Kondo, N., Won, M. J., Naruse, N., Uehara-Aoyama, K., Ikeda, K. & Nitta, A., 01-01-2019, In : Current Pharmaceutical Design. 26, 2, p. 260-264 5 p.

Research output: Contribution to journalArticle

A single-nucleotide polymorphism influences brain morphology in drug-näve patients with major depressive disorder

Katsuki, A., Kakeda, S., Watanabe, K., Igata, R., Otsuka, Y., Kishi, T., Nguyen, L. H., Ueda, I., Iwata, N., Korogi, Y. & Yoshimura, R., 01-01-2019, In : Neuropsychiatric Disease and Treatment. 15, p. 2425-2432 8 p.

Research output: Contribution to journalArticle

Open Access
Open Access
1 Citation (Scopus)

Characteristics of transactive relationship phenomena among older adults, care workers as intermediaries, and the pepper robot with care prevention gymnastics exercises

Tanioka, R., Sugimoto, H., Yasuhara, Y., Ito, H., Osaka, K., Zhao, Y., Kai, Y., Locsin, R. & Tanioka, T., 01-01-2019, In : Journal of Medical Investigation. 66, 1.2, p. 46-49 4 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Comparative genetic architectures of schizophrenia in East Asian and European populations

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Indonesia Schizophrenia Consortium & Genetic REsearch on schizophreniA neTwork-China and the Netherlands (GREAT-CN), 01-12-2019, In : Nature Genetics. 51, 12, p. 1670-1678 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
1 Citation (Scopus)

COMT polymorphism regulates the hippocampal subfield volumes in first-episode, drug-naive patients with major depressive disorder

Otsuka, Y., Kakeda, S., Sugimoto, K., Katsuki, A., Nguyen, L. H., Igata, R., Watanabe, K., Ueda, I., Kishi, T., Iwata, N., Korogi, Y. & Yoshimura, R., 01-01-2019, In : Neuropsychiatric Disease and Treatment. 15, p. 1537-1545 9 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia (Molecular Psychiatry, (2018), 10.1038/s41380-018-0118-1)

for the 16p11.2 European Consortium, for the ENIGMA-CNV working group, 01-01-2019, In : Molecular Psychiatry.

Research output: Contribution to journalComment/debate

Open Access

Daytime light exposure in daily life and depressive symptoms in bipolar disorder: A cross-sectional analysis in the APPLE cohort

Esaki, Y., Kitajima, T., Obayashi, K., Saeki, K., Fujita, K. & Iwata, N., 09-2019, In : Journal of Psychiatric Research. 116, p. 151-156 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Effect of discontinuation v. maintenance of antipsychotic medication on relapse rates in patients with remitted/stable first-episode psychosis: A meta-analysis

Kishi, T., Ikuta, T., Matsui, Y., Inada, K., Matsuda, Y., Mishima, K. & Iwata, N., 01-04-2019, In : Psychological Medicine. 49, 5, p. 772-779 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Efficacy, Tolerability, and Safety of Blonanserin in Schizophrenia: An Updated and Extended Systematic Review and Meta-Analysis of Randomized Controlled Trials

Kishi, T., Matsui, Y., Matsuda, Y., Katsuki, A., Hori, H., Yanagimoto, H., Sanada, K., Morita, K., Yoshimura, R., Shoji, Y., Hagi, K. & Iwata, N., 07-03-2019, In : Pharmacopsychiatry. 52, 2, p. 52-62 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Efficacy and safety of lithium and lamotrigine for the maintenance treatment of clinically stable patients with bipolar disorder: A systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials with an enrichment design

Oya, K., Sakuma, K., Esumi, S., Hashimoto, Y., Hatano, M., Matsuda, Y., Matsui, Y., Miyake, N., Nomura, I., Okuya, M., Iwata, N., Kato, M., Hashimoto, R., Mishima, K., Watanabe, N. & Kishi, T., 01-09-2019, In : Neuropsychopharmacology reports. 39, 3, p. 241-246 6 p.

Research output: Contribution to journalArticle

Open Access

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

CommonMind Consortium, The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium & iPSYCH-GEMS Schizophrenia Working Group, 01-04-2019, In : Nature Genetics. 51, 4, p. 659-674 16 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Genetic effects on white matter integrity in drug-naive patients with major depressive disorder: A diffusion tensor imaging study of 17 genetic loci associated with depressive symptoms

Kakeda, S., Watanabe, K., Katsuki, A., Sugimoto, K., Ueda, I., Igata, N., Kishi, T., Iwata, N., Abe, O., Yoshimura, R. & Korogi, Y., 01-01-2019, In : Neuropsychiatric Disease and Treatment. 15, p. 375-383 9 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Genome-wide association study detected novel susceptibility genes for schizophrenia and shared trans-populations/diseases genetic effect

Ikeda, M., Takahashi, A., Kamatani, Y., Momozawa, Y., Saito, T., Kondo, K., Shimasaki, A., Kawase, K., Sakusabe, T., Iwayama, Y., Toyota, T., Wakuda, T., Kikuchi, M., Kanahara, N., Yamamori, H., Yasuda, Y., Watanabe, Y., Hoya, S., Aleksic, B., Kushima, I. & 12 others, Arai, H., Takaki, M., Hattori, K., Kunugi, H., Okahisa, Y., Ohnuma, T., Ozaki, N., Someya, T., Hashimoto, R., Yoshikawa, T., Kubo, M. & Iwata, N., 01-01-2019, In : Schizophrenia Bulletin. 45, 4, p. 824-834 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Genome-wide association study identifies a novel locus associated with psychological distress in the Japanese population

Koshimizu, H., Nogawa, S., Asano, S., Ikeda, M., Iwata, N., Takahashi, S., Saito, K. & Miyakawa, T., 01-12-2019, In : Translational psychiatry. 9, 1, 52.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Wellcome Trust Case Control Consortium, Cross-Disorder Group of the Psychiatric Genomics Consortium, 23andMe Research Team & Psychosis Endophenotypes International Consortium, 12-12-2019, In : Cell. 179, 7, p. 1469-1482.e11

Research output: Contribution to journalArticle

Open Access
22 Citations (Scopus)

GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture

Matoba, N., Akiyama, M., Ishigaki, K., Kanai, M., Takahashi, A., Momozawa, Y., Ikegawa, S., Ikeda, M., Iwata, N., Hirata, M., Matsuda, K., Kubo, M., Okada, Y. & Kamatani, Y., 01-05-2019, In : Nature Human Behaviour. 3, 5, p. 471-477 7 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population

Suzuki, K., Akiyama, M., Ishigaki, K., Kanai, M., Hosoe, J., Shojima, N., Hozawa, A., Kadota, A., Kuriki, K., Naito, M., Tanno, K., Ishigaki, Y., Hirata, M., Matsuda, K., Iwata, N., Ikeda, M., Sawada, N., Yamaji, T., Iwasaki, M., Ikegawa, S. & 12 others, Maeda, S., Murakami, Y., Wakai, K., Tsugane, S., Sasaki, M., Yamamoto, M., Okada, Y., Kubo, M., Kamatani, Y., Horikoshi, M., Yamauchi, T. & Kadowaki, T., 01-03-2019, In : Nature Genetics. 51, 3, p. 379-386 8 p.

Research output: Contribution to journalLetter

24 Citations (Scopus)

Light exposure at night and sleep quality in bipolar disorder: The APPLE cohort study

Esaki, Y., Kitajima, T., Obayashi, K., Saeki, K., Fujita, K. & Iwata, N., 01-10-2019, In : Journal of Affective Disorders. 257, p. 314-320 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
Open Access
2 Citations (Scopus)

New subtyping of insomnia disorder

Kitajima, T., 02-2019, In : The Lancet Psychiatry. 6, 2, p. 86-88 3 p.

Research output: Contribution to journalComment/debate

2 Citations (Scopus)

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia

Wellcome Trust Case Control Consortium 2 & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 04-2019, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (Nature Genetics, (2019), 51, 4, (659-674), 10.1038/s41588-019-0364-4)

iPSYCH-GEMS Schizophrenia Working Group, CommonMind Consortium & The Schizophrenia Working Group of the Psychiatric Genomics Consortium, 01-06-2019, In : Nature Genetics. 51, 6, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Quetiapine extended-release vs olanzapine for Japanese patients with bipolar depression: A Bayesian analysis

Kishi, T., Ikuta, T., Matsuda, Y. & Iwata, N., 01-09-2019, In : Neuropsychopharmacology reports. 39, 3, p. 256-259 4 p.

Research output: Contribution to journalArticle

Open Access