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Article

[Successful treatment with bortezomib for a patient with plasma cell leukemia accompanied by severe hyperbilirubinemia].

Mino, T., Sakai, A., Kinoshita, M., Yoshida, T., Mihara, K., Imagawa, J. & Kimura, A., 01-2012, In : [Rinshō ketsueki] The Japanese journal of clinical hematology. 53, 1, p. 92-96 5 p.

Research output: Contribution to journalArticle

[Therapeutic strategy for breast cancer stem cells].

Yoshida, G. J. & Saya, H., 09-2012, In : Unknown Journal. 70 Suppl 7, p. 243-248 6 p.

Research output: Contribution to journalArticle

17β-estradiol attenuates hippocampal neuronal loss and cognitive dysfunction induced by chronic restraint stress in ovariectomized rats

Takuma, K., Matsuo, A., Himeno, Y., Hoshina, Y., Ohno, Y., Funatsu, Y., Arai, S., Kamei, H., Mizoguchi, H., Nagai, T., Koike, K., Inoue, M. & Yamada, K., 25-04-2007, In : Neuroscience. 146, 1, p. 60-68 9 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

18F-FDG PET imaging for identifying the dynamics of intestinal disease caused by SFTSV infection in a mouse model

Hayasaka, D., Nishi, K., Fuchigami, T., Shiogama, K., Onouchi, T., Shimada, S., Tsutsumi, Y. & Morita, K., 2016, In : Oncotarget. 7, 1, p. 140-147 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

2-Nitroimidazoles induce mitochondrial stress and ferroptosis in glioma stem cells residing in a hypoxic niche

Koike, N., Kota, R., Naito, Y., Hayakawa, N., Matsuura, T., Hishiki, T., Onishi, N., Fukada, J., Suematsu, M., Shigematsu, N., Saya, H. & Sampetrean, O., 01-12-2020, In : Communications biology. 3, 1, 450.

Research output: Contribution to journalArticle

Open Access

A basic study on self-reconstitution of alveolar epithelium-like cells by tissue stem cells in mouse lung

Hayashi, M., Yamamoto, N., Hiramatsu, N., Isogai, S., Gotoh, Y., Goto, Y., Kondo, M. & Imaizumi, K., 01-10-2018, In : In Vitro Cellular and Developmental Biology - Animal. 54, 9, p. 648-657 10 p.

Research output: Contribution to journalArticle

ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population

Fukunaga, K., Nakagawa, H., Ishikawa, T., Kubo, M. & Mushiroda, T., 13-06-2016, In : BMC Genetics. 17, 1, 79.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Aberrant smad3 phosphoisoforms in cyst-lining epithelial cells in the CPK mouse, a model of autosomal recessive polycystic kidney disease

Hama, T., Nakanishi, K., Sato, M., Mukaiyama, H., Togawa, H., Shima, Y., Miyajima, M., Nozu, K., Nagao, S., Takahashi, H., Sako, M., Iijima, K., Yoshikawa, N. & Suzuki, H., 12-2017, In : American Journal of Physiology - Renal Physiology. 313, 6, p. F1223-F1231

Research output: Contribution to journalArticle

1 Citation (Scopus)

Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits

Woronowicz, A., Koshimizu, H., Chang, S. Y., Cawley, N. X., Hill, J. M., Rodriguiz, R. M., Abebe, D., Dorfman, C., Senatorov, V., Zhou, A., Xiong, Z. G., Wetsel, W. C. & Loh, Y. P., 2008, In : Hippocampus. 18, 10, p. 1051-1063 13 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

A case of anterior-type persistent hyperplastic primary vitreous

Majima, K., Kiribuchi, K., Itonaga, K. & Yamamoto, N., 2002, In : Journal of Pediatric Ophthalmology and Strabismus. 39, 6, p. 355-357 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A case of dihydropyrimidinase deficiency incidentally detected by urine metabolome analysis

Tsuchiya, H., Akiyama, T., Kuhara, T., Nakajima, Y., Ohse, M., Kurahashi, H., Kato, T., Maeda, Y., Yoshinaga, H. & Kobayashi, K., 03-2019, In : Brain and Development. 41, 3, p. 280-284 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Accelerated differentiation of melanocyte stem cells contributes to the formation of hyperpigmented maculae

Yamada, T., Hasegawa, S., Inoue, Y., Date, Y., Arima, M., Yagami, A., Iwata, Y., Takahashi, M., Yamamoto, N., Mizutani, H., Nakata, S., Matsunaga, K. & Akamatsu, H., 01-01-2014, In : Experimental Dermatology. 23, 9, p. 652-658 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Acid load during total parenteral nutrition: Comparison of hydrochloric acid and acetic acid on plasma acid-base balance

Sugiura, S. I., Inagaki, K., Noda, Y., Nagai, T. & Nabeshima, T., 04-2000, In : Nutrition. 16, 4, p. 260-263 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A comprehensive analysis of teleost MHC class i sequences

Grimholt, U., Tsukamoto, K., Azuma, T., Leong, J., Koop, B. F. & Dijkstra, J. M., 12-12-2015, In : BMC Evolutionary Biology. 15, 1, 32.

Research output: Contribution to journalArticle

41 Citations (Scopus)

A cross-ethnic survey of CFB and SLC44A4, Indian ulcerative colitis GWAS hits, underscores their potential role in disease susceptibility

Gupta, A., Juyal, G., Sood, A., Midha, V., Yamazaki, K., Vich Vila, A., Esaki, M., Matsui, T., Takahashi, A., Kubo, M., Weersma, R. K. & Thelma, B. K., 01-01-2016, In : European Journal of Human Genetics. 25, 1, p. 111-112 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells

Oguma, K., Oshima, H., Aoki, M., Uchio, R., Naka, K., Nakamura, S., Hirao, A., Saya, H., Taketo, M. M. & Oshima, M., 18-06-2008, In : EMBO Journal. 27, 12, p. 1671-1681 11 p.

Research output: Contribution to journalArticle

215 Citations (Scopus)

Activated T-cell-mediated immunotherapy with a chimeric receptor against CD38 in b-cell non-hodgkin lymphoma

Mihara, K., Yanagihara, K., Takigahira, M., Imai, C., Kitanaka, A., Takihara, Y. & Kimura, A., 09-2009, In : Journal of Immunotherapy. 32, 7, p. 737-743 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Activation of Aurora-A is essential for neuronal migration via modulation of microtubule organization

Takitoh, T., Kumamoto, K., Wang, C. C., Sato, M., Toba, S., Wynshaw-Boris, A. & Hirotsune, S., 08-08-2012, In : Journal of Neuroscience. 32, 32, p. 11050-11066 17 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Activation of m-Calpain Is Required for Chromosome Alignment on the Metaphase Plate during Mitosis

Honda, S., Marumoto, T., Hirota, T., Nitta, M., Arima, Y., Ogawa, M. & Saya, H., 12-03-2004, In : Journal of Biological Chemistry. 279, 11, p. 10615-10623 9 p.

Research output: Contribution to journalArticle

Open Access
35 Citations (Scopus)

Activation of post-synaptic dopamine D receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling.

Ito, M., Nagai, T., Mizoguchi, H., Sato, K., Hayase, M., Otsuka, N., Fukakusa, A., Kumagai, N., Kim, H. C., Nabeshima, T., Takuma, K. & Yamada, K., 01-12-2007, In : Journal of neurochemistry. 103, 6, p. 2589-2596 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer Cells

Ishimoto, T., Miyake, K., Nandi, T., Yashiro, M., Onishi, N., Huang, K. K., Lin, S. J., Kalpana, R., Tay, S. T., Suzuki, Y., Cho, B. C., Kuroda, D., Arima, K., Izumi, D., Iwatsuki, M., Baba, Y., Oki, E., Watanabe, M., Saya, H., Hirakawa, K. & 2 others, Baba, H. & Tan, P., 07-2017, In : Gastroenterology. 153, 1, p. 191-204.e16

Research output: Contribution to journalArticle

50 Citations (Scopus)

ADAM-17 associated with CD44 cleavage and metastasis in oral squamous cell carcinoma

Takamune, Y., Ikebe, T., Nagano, O., Nakayama, H., Ota, K., Obayashi, T., Saya, H. & Shinohara, M., 01-02-2007, In : Virchows Archiv. 450, 2, p. 169-177 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells

Tominaga, K., Shimamura, T., Kimura, N., Murayama, T., Matsubara, D., Kanauchi, H., Niida, A., Shimizu, S., Nishioka, K., Tsuji, E. I., Yano, M., Sugano, S., Shimono, Y., Ishii, H., Saya, H., Mori, M., Akashi, K., Tada, K. I., Ogawa, T., Tojo, A. & 2 others, Miyano, S. & Gotoh, N., 02-03-2017, In : Oncogene. 36, 9, p. 1276-1286 11 p.

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)

A deletion mutation in myosin heavy chain 11 causing familial thoracic aortic dissection in two Japanese pedigrees

Imai, Y., Morita, H., Takeda, N., Miya, F., Hyodo, H., Fujita, D., Tajima, T., Tsunoda, T., Nagai, R., Kubo, M. & Komuro, I., 22-07-2015, In : International Journal of Cardiology. 195, p. 290-292 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Adenomatous polyposis coli heterozygous knockout mice display hypoactivity and age-dependent working memory deficits

Koshimizu, H., Fukui, Y., Takao, K., Ohira, K., Tanda, K., Nakanishi, K., Toyama, K., Oshima, M., Taketo, M. M. & Miyakawa, T., 12-2011, In : Frontiers in Behavioral Neuroscience. DECEMBER

Research output: Contribution to journalArticle

16 Citations (Scopus)

Adherence of lyme disease spirochetes to rat lymphocytes

Fumarola, D., Cedola, M. C., Guanti, G., Matsuura, A., Uede, T. & Jirillo, E., 1986, In : Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A. 263, 1-2, p. 146-150 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A disturbance of intestinal epithelial cell population and kinetics in APC1638T mice

Wang, T., Onouchi, T., Yamada, N. O., Matsuda, S. & Senda, T., 01-06-2017, In : Medical Molecular Morphology. 50, 2, p. 94-102 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Adjustment of cell-type composition minimizes systematic bias in blood DNA methylation profiles derived by DNA collection protocols

Shiwa, Y., Hachiya, T., Furukawa, R., Ohmomo, H., Ono, K., Kudo, H., Hata, J., Hozawa, A., Iwasaki, M., Matsuda, K., Minegishi, N., Satoh, M., Tanno, K., Yamaji, T., Wakai, K., Hitomi, J., Kiyohara, Y., Kubo, M., Tanaka, H., Tsugane, S. & 3 others, Yamamoto, M., Sobue, K. & Shimizu, A., 01-01-2016, In : PloS one. 11, 1, e0147519.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model

Imai, K., Kotani, T., Tsuda, H., Nakano, T., Ushida, T., Iwase, A., Nagai, T., Toyokuni, S., Suzumura, A. & Kikkawa, F., 01-12-2018, In : Scientific reports. 8, 1, 9221.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

A dried blood sample on filter paper is suitable for detecting Plasmodium falciparum gametocytes by reverse transcription polymerase chain reaction

Maeno, Y., Nakazawa, S., Dao, L. D., Yamamoto, N., Giang, N. D., Van Hanh, T., Thuan, L. K. & Taniguchi, K., 01-08-2008, In : Acta Tropica. 107, 2, p. 121-127 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
Open Access
2 Citations (Scopus)

A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis

Ogura, Y., Kou, I., Miura, S., Takahashi, A., Xu, L., Takeda, K., Takahashi, Y., Kono, K., Kawakami, N., Uno, K., Ito, M., Minami, S., Yonezawa, I., Yanagida, H., Taneichi, H., Zhu, Z., Tsuji, T., Suzuki, T., Sudo, H., Kotani, T. & 15 others, Watanabe, K., Hosogane, N., Okada, E., Iida, A., Nakajima, M., Sudo, A., Chiba, K., Hiraki, Y., Toyama, Y., Qiu, Y., Shukunami, C., Kamatani, Y., Kubo, M., Matsumoto, M. & Ikegawa, S., 06-08-2015, In : American Journal of Human Genetics. 97, 2, p. 337-342 6 p., 1911.

Research output: Contribution to journalArticle

65 Citations (Scopus)

A functional SNP in FLT1 increases risk of coronary artery disease in a Japanese population

Konta, A., Ozaki, K., Sakata, Y., Takahashi, A., Morizono, T., Suna, S., Onouchi, Y., Tsunoda, T., Kubo, M., Komuro, I., Eishi, Y. & Tanaka, T., 01-05-2016, In : Journal of Human Genetics. 61, 5, p. 435-441 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

A functional variant in MIR4300HG, the host gene of microRNA MIR4300 is associated with progression of adolescent idiopathic scoliosis

Japan Scoliosis Clinical Research Group, 15-10-2017, In : Human molecular genetics. 26, 20, p. 4086-4092 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression

Akamatsu, S., Takata, R., Ashikawa, K., Hosono, N., Kamatani, N., Fujioka, T., Ogawa, O., Kubo, M., Nakamura, Y. & Nakagawa, H., 17-08-2010, In : Human molecular genetics. 19, 21, p. 4265-4272 8 p., ddq350.

Research output: Contribution to journalArticle

22 Citations (Scopus)

A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese

Iida, A., Takahashi, A., Kubo, M., Saito, S., Hosono, N., Ohnishi, Y., Kiyotani, K., Mushiroda, T., Nakajima, M., Ozaki, K., Tanaka, T., Tsunoda, T., Oshima, S., Sano, M., Kamei, T., Tokuda, T., Aoki, M., Hasegawa, K., Mizoguchi, K., Morita, M. & 12 others, Takahashi, Y., Katsuno, M., Atsuta, N., Watanabe, H., Tanaka, F., Kaji, R., Nakano, I., Kamatani, N., Tsuji, S., Sobue, G., Nakamura, Y. & Ikegawa, S., 09-2011, In : Human molecular genetics. 20, 18, p. 3684-3692 9 p., ddr268.

Research output: Contribution to journalArticle

38 Citations (Scopus)

A genome-wide association analysis identifies NMNAT2 and HCP5 as susceptibility loci for Kawasaki disease

Kim, J. J., Yun, S. W., Yu, J. J., Yoon, K. L., Lee, K. Y., Kil, H. R., Kim, G. B., Han, M. K., Song, M. S., Lee, H. D., Ha, K. S., Sohn, S., Johnson, T. A., Takahashi, A., Kubo, M., Tsunoda, T., Ito, K., Onouchi, Y., Hong, Y. M., Jang, G. Y. & 1 others, Lee, J. K., 01-12-2017, In : Journal of Human Genetics. 62, 12, p. 1023-1029 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

A genome-wide association identified the common genetic variants influence disease severity in β0-thalassemia/hemoglobin e

Nuinoon, M., Makarasara, W., Mushiroda, T., Setianingsih, I., Wahidiyat, P. A., Sripichai, O., Kumasaka, N., Takahashi, A., Svasti, S., Munkongdee, T., Mahasirimongkol, S., Peerapittayamongkol, C., Viprakasit, V., Kamatani, N., Winichagoon, P., Kubo, M., Nakamura, Y. & Fucharoen, S., 01-01-2010, In : Human Genetics. 127, 3, p. 303-314 12 p.

Research output: Contribution to journalArticle

127 Citations (Scopus)

A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese

Okada, Y., Shimane, K., Kochi, Y., Tahira, T., Suzuki, A., Higasa, K., Takahashi, A., Horita, T., Atsumi, T., Ishii, T., Okamoto, A., Fujio, K., Hirakata, M., Amano, H., Kondo, Y., Ito, S., Takada, K., Mimori, A., Saito, K., Kamachi, M. & 24 others, Kawaguchi, Y., Ikari, K., Mohammed, O. W., Matsuda, K., Terao, C., Ohmura, K., Myouzen, K., Hosono, N., Tsunoda, T., Nishimoto, N., Mimori, T., Matsuda, F., Tanaka, Y., Sumida, T., Yamanaka, H., Takasaki, Y., Koike, T., Horiuchi, T., Hayashi, K., Kubo, M., Kamatani, N., Yamada, R., Nakamura, Y. & Yamamoto, K., 01-2012, In : PLoS Genetics. 8, 1, e1002455.

Research output: Contribution to journalArticle

78 Citations (Scopus)

A genome-wide association study identifies 2 susceptibility loci for crohn's disease in a Japanese population

Yamazaki, K., Umeno, J., Takahashi, A., Hirano, A., Johnson, T. A., Kumasaka, N., Morizono, T., Hosono, N., Kawaguchi, T., Takazoe, M., Yamada, T., Suzuki, Y., Tanaka, H., Motoya, S., Hosokawa, M., Arimura, Y., Shinomura, Y., Matsui, T., Matsumoto, T., Iida, M. & 4 others, Tsunoda, T., Nakamura, Y., Kamatani, N. & Kubo, M., 04-2013, In : Gastroenterology. 144, 4, p. 781-788 8 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese

Elgazzar, S., Zembutsu, H., Takahashi, A., Kubo, M., Aki, F., Hirata, K., Takatsuka, Y., Okazaki, M., Ohsumi, S., Yamakawa, T., Sasa, M., Katagiri, T., Miki, Y. & Nakamura, Y., 12-2012, In : Journal of Human Genetics. 57, 12, p. 766-771 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis

Mushiroda, T., Wattanapokayakit, S., Takahashi, A., Nukiwa, T., Kudoh, S., Ogura, T., Taniguchi, H., Kubo, M., Kamatani, N. & Nakamura, Y., 10-2008, In : Journal of Medical Genetics. 45, 10, p. 654-656 3 p.

Research output: Contribution to journalArticle

133 Citations (Scopus)

A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy

Kiyotani, K., Uno, S., Mushiroda, T., Takahashi, A., Kubo, M., Mitsuhata, N., Ina, S., Kihara, C., Kimura, Y., Yamaue, H., Hirata, K., Nakamura, Y. & Zembutsu, H., 04-2012, In : Pharmacogenetics and genomics. 22, 4, p. 229-235 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

A genome-wide association study identifies four susceptibility loci for keloid in the japanese population

Nakashima, M., Chung, S., Takahashi, A., Kamatani, N., Kawaguchi, T., Tsunoda, T., Hosono, N., Kubo, M., Nakamura, Y. & Zembutsu, H., 09-2010, In : Nature Genetics. 42, 9, p. 768-772 5 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese

Uno, S., Zembutsu, H., Hirasawa, A., Takahashi, A., Kubo, M., Akahane, T., Aoki, D., Kamatani, N., Hirata, K. & Nakamura, Y., 01-08-2010, In : Nature Genetics. 42, 8, p. 707-710 4 p.

Research output: Contribution to journalArticle

182 Citations (Scopus)

A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma

Ng, C. C., Yew, P. Y., Puah, S. M., Krishnan, G., Yap, L. F., Teo, S. H., Lim, P. V. H., Govindaraju, S., Ratnavelu, K., Sam, C. K., Takahashi, A., Kubo, M., Kamatani, N., Nakamura, Y. & Mushiroda, T., 07-2009, In : Journal of Human Genetics. 54, 7, p. 392-397 6 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese

Kiyotani, K., Mushiroda, T., Tsunoda, T., Morizono, T., Hosono, N., Kubo, M., Tanigawara, Y., Imamura, C. K., Flockhart, D. A., Aki, F., Hirata, K., Takatsuka, Y., Okazaki, M., Ohsumi, S., Yamakawa, T., Sasa, M., Nakamura, Y. & Zembutsu, H., 04-2012, In : Human molecular genetics. 21, 7, p. 1665-1672 8 p., ddr597.

Research output: Contribution to journalArticle

43 Citations (Scopus)

A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101

Baldwin, R. M., Owzar, K., Zembutsu, H., Chhibber, A., Kubo, M., Jiang, C., Watson, D., Eclov, R. J., Mefford, J., McLeod, H. L., Friedman, P. N., Hudis, C. A., Winer, E. P., Jorgenson, E. M., Witte, J. S., Shulman, L. N., Nakamura, Y., Ratain, M. J. & Kroetz, D. L., 15-09-2012, In : Clinical Cancer Research. 18, 18, p. 5099-5109 11 p.

Research output: Contribution to journalArticle

123 Citations (Scopus)

A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis

Jongjaroenprasert, W., Phusantisampan, T., Mahasirimongkol, S., Mushiroda, T., Hirankarn, N., Snabboon, T., Chanprasertyotin, S., Tantiwong, P., Soonthornpun, S., Rattanapichart, P., Mamanasiri, S., Himathongkam, T., Ongphiphadhanakul, B., Takahashi, A., Kamatani, N., Kubo, M. & Nakamura, Y., 05-2012, In : Journal of Human Genetics. 57, 5, p. 301-304 4 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)