Research Promotion and Support Headquarters

Research Output

2016

A cross-ethnic survey of CFB and SLC44A4, Indian ulcerative colitis GWAS hits, underscores their potential role in disease susceptibility

Gupta, A., Juyal, G., Sood, A., Midha, V., Yamazaki, K., Vich Vila, A., Esaki, M., Matsui, T., Takahashi, A., Kubo, M., Weersma, R. K. & Thelma, B. K., 01-01-2016, In : European Journal of Human Genetics. 25, 1, p. 111-112 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Adjustment of cell-type composition minimizes systematic bias in blood DNA methylation profiles derived by DNA collection protocols

Shiwa, Y., Hachiya, T., Furukawa, R., Ohmomo, H., Ono, K., Kudo, H., Hata, J., Hozawa, A., Iwasaki, M., Matsuda, K., Minegishi, N., Satoh, M., Tanno, K., Yamaji, T., Wakai, K., Hitomi, J., Kiyohara, Y., Kubo, M., Tanaka, H., Tsugane, S. & 3 others, Yamamoto, M., Sobue, K. & Shimizu, A., 01-01-2016, In : PloS one. 11, 1, e0147519.

Research output: Contribution to journalArticle

13 Citations (Scopus)

A functional SNP in FLT1 increases risk of coronary artery disease in a Japanese population

Konta, A., Ozaki, K., Sakata, Y., Takahashi, A., Morizono, T., Suna, S., Onouchi, Y., Tsunoda, T., Kubo, M., Komuro, I., Eishi, Y. & Tanaka, T., 01-05-2016, In : Journal of Human Genetics. 61, 5, p. 435-441 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

A genome wide study of copy number variation associated with nasopharyngeal carcinoma in Malaysian Chinese Identifies CNVs at 11q14.3 and 6p21.3 as Candidate Loci

Low, J. S. Y., Chin, Y. M., Mushiroda, T., Kubo, M., Govindasamy, G. K., Pua, K. C., Yap, Y. Y., Yap, L. F., Subramaniam, S. K., Ong, C. A., Tan, T. Y., Khoo, A. S. B. & Ng, C. C., 05-01-2016, In : PloS one. 11, 1, e0145774.

Research output: Contribution to journalArticle

11 Citations (Scopus)

ALDH2 polymorphism is associated with fasting blood glucose through alcohol consumption in Japanese men

Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group, 01-01-2016, In : Nagoya journal of medical science. 78, 2, p. 183-193 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

All-trans retinoic acid enhances cytotoxic effect of T cells with an anti-CD38 chimeric antigen receptor in acute myeloid leukemia

Yoshida, T., Mihara, K., Takei, Y., Yanagihara, K., Kubo, T., Bhattacharyya, J., Imai, C., Mino, T., Takihara, Y. & Ichinohe, T., 01-12-2016, In : Clinical and Translational Immunology. 5, 12, e116.

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)

A Longitudinal HbA1c Model Elucidates Genes Linked to Disease Progression on Metformin

Goswami, S., Yee, S. W., Xu, F., Sridhar, S. B., Mosley, J. D., Takahashi, A., Kubo, M., Maeda, S., Davis, R. L., Roden, D. M., Hedderson, M. M., Giacomini, K. M. & Savic, R. M., 01-11-2016, In : Clinical Pharmacology and Therapeutics. p. 537-547 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A lower volume culture method for obtaining a larger yield of neuron-like cells from mesenchymal stem cells

Shimomura, A., Iizuka-Kogo, A., Yamamoto, N. & Nomura, R., 01-06-2016, In : Medical Molecular Morphology. 49, 2, p. 119-126 8 p.

Research output: Contribution to journalArticle

A rapid functional decline type of amyotrophic lateral sclerosis is linked to low expression of TTN

Watanabe, H., Atsuta, N., Hirakawa, A., Nakamura, R., Nakatochi, M., Ishigaki, S., Iida, A., Ikegawa, S., Kubo, M., Yokoi, D., Watanabe, H., Ito, M., Katsuno, M., Izumi, Y., Morita, M., Kanai, K., Taniguchi, A., Aiba, I., Abe, K., Mizoguchi, K. & 12 others, Oda, M., Kano, O., Okamoto, K., Kuwabara, S., Hasegawa, K., Imai, T., Kawata, A., Aoki, M., Tsuji, S., Nakashima, K., Kaji, R. & Sobue, G., 08-01-2016, In : Journal of Neurology, Neurosurgery and Psychiatry. 87, 8, p. 851-858 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

A simple method of bronchial occlusion with silicone spigots (Endobronchial Watanabe Spigot; EWS®) using a curette

Morikawa, S., Okamura, T., Minezawa, T., Goto, Y., Hayashi, M., Yamaguchi, T., Isogai, S., Mieno, Y., Yamamoto, N., Uozu, S., Nakanishi, T., Okazawa, M. & Imaizumi, K., 01-12-2016, In : Therapeutic Advances in Respiratory Disease. 10, 6, p. 518-524 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors

Middlebrooks, C. D., Banday, A. R., Matsuda, K., Udquim, K. I., Onabajo, O. O., Paquin, A., Figueroa, J. D., Zhu, B., Koutros, S., Kubo, M., Shuin, T., Freedman, N. D., Kogevinas, M., Malats, N., Chanock, S. J., Garcia-Closas, M., Silverman, D. T., Rothman, N. & Prokunina-Olsson, L., 01-11-2016, In : Nature Genetics. 48, 11, p. 1330-1338 9 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma

Shiraishi, K., Okada, Y., Takahashi, A., Kamatani, Y., Momozawa, Y., Ashikawa, K., Kunitoh, H., Matsumoto, S., Takano, A., Shimizu, K., Goto, A., Tsuta, K., Watanabe, S. I., Ohe, Y., Watanabe, Y., Goto, Y., Nokihara, H., Furuta, K., Yoshida, A., Goto, K. & 26 others, Hishida, T., Tsuboi, M., Tsuchihara, K., Miyagi, Y., Nakayama, H., Yokose, T., Tanaka, K., Nagashima, T., Ohtaki, Y., Maeda, D., Imai, K., Minamiya, Y., Sakamoto, H., Saito, A., Shimada, Y., Sunami, K., Saito, M., Inazawa, J., Nakamura, Y., Yoshida, T., Yokota, J., Matsuda, F., Matsuo, K., Daigo, Y., Kubo, M. & Kohno, T., 09-08-2016, In : Nature Communications. 7, 12451.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Associations between dietary patterns, ADRβ2 Gln27Glu and ADRβ3 Trp64Arg with regard to serum triglyceride levels: J-MICC study

Nanri, H., Nishida, Y., Nakamura, K., Tanaka, K., Naito, M., Yin, G., Hamajima, N., Takashima, N., Suzuki, S., Nindita, Y., Kohno, M., Uemura, H., Koyama, T., Hosono, S., Mikami, H., Kubo, M. & Tanaka, H., 06-09-2016, In : Nutrients. 8, 9, 545.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Association study of a functional variant on ABCG2 gene with sunitinib-induced severe adverse drug reaction

Low, S. K., Fukunaga, K., Takahashi, A., Matsuda, K., Hongo, F., Nakanishi, H., Kitamura, H., Inoue, T., Kato, Y., Tomita, Y., Fukasawa, S., Tanaka, T., Nishimura, K., Uemura, H., Hara, I., Fujisawa, M., Matsuyama, H., Hashine, K., Tatsugami, K., Enokida, H. & 3 others, Kubo, M., Miki, T. & Mushiroda, T., 02-2016, In : PloS one. 11, 2, e0148177.

Research output: Contribution to journalArticle

24 Citations (Scopus)

A variety of human monoclonal antibodies against epidermal growth factor receptor isolated from a phage antibody library

Kurosawa, G., Kondo, M. & Kurosawa, Y., 04-11-2016, In : Biochemical and Biophysical Research Communications. 480, 1, p. 94-100 7 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Cell-Surface Protein Profiling Identifies Distinctive Markers of Progenitor Cells in Human Skeletal Muscle

Uezumi, A., Nakatani, M., Ikemoto-Uezumi, M., Yamamoto, N., Morita, M., Yamaguchi, A., Yamada, H., Kasai, T., Masuda, S., Narita, A., Miyagoe-Suzuki, Y., Takeda, S., Fukada, S. I., Nishino, I. & Tsuchida, K., 09-08-2016, In : Stem Cell Reports. 7, 2, p. 263-278 16 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Classification of 27 tumor-associated antigens by histochemical analysis of 36 freshly resected lung cancer tissues

Kurosawa, G., Sugiura, M., Hattori, Y., Tsuda, H. & Kurosawa, Y., 08-11-2016, In : International journal of molecular sciences. 17, 11, 1862.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis

Okada, Y., Suzuki, A., Ikari, K., Terao, C., Kochi, Y., Ohmura, K., Higasa, K., Akiyama, M., Ashikawa, K., Kanai, M., Hirata, J., Suita, N., Teo, Y. Y., Xu, H., Bae, S. C., Takahashi, A., Momozawa, Y., Matsuda, K., Momohara, S., Taniguchi, A. & 9 others, Yamada, R., Mimori, T., Kubo, M., Brown, M. A., Raychaudhuri, S., Matsuda, F., Yamanaka, H., Kamatani, Y. & Yamamoto, K., 04-08-2016, In : American Journal of Human Genetics. 99, 2, p. 366-374 9 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Diagnostic copper imaging of Menkes disease by synchrotron radiation-generated X-ray fluorescence analysis

Kinebuchi, M., Matsuura, A., Kiyono, T., Nomura, Y. & Kimura, S., 15-09-2016, In : Scientific reports. 6, 33247.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Effects of exercise and bryostatin-1 on serotonin dynamics after cerebral infarction

Mizutani, K., Sonoda, S., Wakita, H., Okazaki, H., Katoh, Y., Chihara, T. & Shimpo, K., 15-06-2016, In : NeuroReport. 27, 9, p. 659-664 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Effects of occlusal disharmony on the hippocampal dentate gyrus in aged senescence-accelerated mouse prone 8 (SAMP8)

Mori, D., Miyake, H., Mizutani, K., Shimpo, K., Sonoda, S., Yamamoto, T., Fujiwara, S. & Kubo, K. Y., 05-2016, In : Archives of Oral Biology. 65, p. 95-101 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Effects of self-reported calorie restriction on correlations between SIRT1 polymorphisms and body mass index and long-term weight change

Higashibata, T., Wakai, K., Naito, M., Morita, E., Hishida, A., Hamajima, N., Hara, M., Suzuki, S., Hosono, S., Takashima, N., Ohnaka, K., Takada, A., Mikami, H., Watanabe, Y., Uemura, H., Kubo, M. & Tanaka, H., 05-12-2016, In : Gene. 594, 1, p. 16-22 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Electron microscopic detection of pathogens and neutrophil extracellular traps

Tsutsumi, Y. & Onouchi, T., 01-01-2016, In : Microscopy. 65, p. i18

Research output: Contribution to journalArticle

1 Citation (Scopus)

Erratum: Arsenic trioxide sensitizes glioblastoma to a myc inhibitor (PLoS ONE 10:6 (e0128288) DOI 10.1371/journal.pone.0128288)

Yoshimura, Y., Shiino, A., Muraki, K., Fukami, T., Yamada, S., Satow, T., Fukuda, M., Saiki, M., Hojo, M., Miyamoto, S., Onishi, N., Saya, H., Inubushi, T., Nozaki, K. & Tanigaki, K., 02-2016, In : PloS one. 11, 2, e0149826.

Research output: Contribution to journalComment/debate

Open Access

Erratum: Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer (Nature Genetics (2016) DOI: 10.1038/ng.3547)

Fujimoto, A., Furuta, M., Totoki, Y., Tsunoda, T., Kato, M., Shiraishi, Y., Tanaka, H., Taniguchi, H., Kawakami, Y., Ueno, M., Gotoh, K., Ariizumi, S. I., Wardell, C. P., Hayami, S., Nakamura, T., Aikata, H., Arihiro, K., Boroevich, K. A., Abe, T., Nakano, K. & 31 others, Maejima, K., Sasaki-Oku, A., Ohsawa, A., Shibuya, T., Nakamura, H., Hama, N., Hosoda, F., Arai, Y., Ohashi, S., Urushidate, T., Nagae, G., Yamamoto, S., Ueda, H., Tatsuno, K., Ojima, H., Hiraoka, N., Okusaka, T., Kubo, M., Marubashi, S., Yamada, T., Hirano, S., Yamamoto, M., Ohdan, H., Shimada, K., Ishikawa, O., Yamaue, H., Chayama, K., Miyano, S., Aburatani, H., Shibata, T. & Nakagawa, H., 01-06-2016, In : Nature Genetics. 48, 6, 1 p.

Research output: Contribution to journalComment/debate

Establishment of a new immortalized human corneal epithelial cell line (iHCE-NY1) for use in evaluating eye irritancy by in vitro test methods

Yamamoto, N., Kato, Y., Sato, A., Hiramatsu, N., Yamashita, H., Ohkuma, M., Miyachi, E. I., Horiguchi, M., Hirano, K. & Kojima, H., 01-08-2016, In : In Vitro Cellular and Developmental Biology - Animal. 52, 7, p. 742-748 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Estrogen, SNP-dependent chemokine expression and selective estrogen receptor modulator regulation

Ho, M. F., Bongartz, T., Liu, M., Kalari, K. R., Goss, P. E., Shepherd, L. E., Goetz, M. P., Kubo, M., Ingle, J. N., Wang, L. & Weinshilboum, R. M., 03-2016, In : Molecular Endocrinology. 30, 3, p. 382-398 17 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Full Genome Characterization of Novel DS-1-Like G8P[8] Rotavirus Strains that Have Emerged in Thailand: Reassortment of Bovine and Human Rotavirus Gene Segments in Emerging DS-1-Like Intergenogroup Reassortant Strains

Tacharoenmuang, R., Komoto, S., Guntapong, R., Ide, T., Sinchai, P., Upachai, S., Yoshikawa, T., Tharmaphornpilas, P., Sangkitporn, S. & Taniguchi, K., 11-2016, In : PloS one. 11, 11, 165826.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Pattaro, C., Teumer, A., Gorski, M., Chu, A. Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M. H., Pers, T. H., Johnson, A. D., Ko, Y. A., Fuchsberger, C., Tayo, B. & 678 others, Nalls, M., Feitosa, M. F., Isaacs, A., Dehghan, A., D'Adamo, P., Adeyemo, A., Dieffenbach, A. K., Zonderman, A. B., Nolte, I. M., Van Der Most, P. J., Wright, A. F., Shuldiner, A. R., Morrison, A. C., Hofman, A., Smith, A. V., Dreisbach, A. W., Franke, A., Uitterlinden, A. G., Metspalu, A., Tonjes, A., Lupo, A., Robino, A., Johansson, Å., Demirkan, A., Kollerits, B., Freedman, B. I., Ponte, B., Oostra, B. A., Paulweber, B., Krämer, B. K., Mitchell, B. D., Buckley, B. M., Peralta, C. A., Hayward, C., Helmer, C., Rotimi, C. N., Shaffer, C. M., Müller, C., Sala, C., Van Duijn, C. M., Saint-Pierre, A., Ackermann, D., Shriner, D., Ruggiero, D., Toniolo, D., Lu, Y., Cusi, D., Czamara, D., Ellinghaus, D., Siscovick, D. S., Ruderfer, D., Gieger, C., Grallert, H., Rochtchina, E., Atkinson, E. J., Holliday, E. G., Boerwinkle, E., Salvi, E., Bottinger, E. P., Murgia, F., Rivadeneira, F., Ernst, F., Kronenberg, F., Hu, F. B., Navis, G. J., Curhan, G. C., Ehret, G. B., Homuth, G., Coassin, S., Thun, G. A., Pistis, G., Gambaro, G., Malerba, G., Montgomery, G. W., Eiriksdottir, G., Jacobs, G., Li, G., Wichmann, H. E., Campbell, H., Schmidt, H., Wallaschofski, H., Völzke, H., Brenner, H., Kroemer, H. K., Kramer, H., Lin, H., Leach, I. M., Ford, I., Guessous, I., Rudan, I., Prokopenko, I., Borecki, I., Heid, I. M., Kolcic, I., Persico, I., Jukema, J. W., Wilson, J. F., Felix, J. F., Divers, J., Lambert, J. C., Stafford, J. M., Gaspoz, J. M., Smith, J. A., Faul, J. D., Wang, J. J., Ding, J., Hirschhorn, J. N., Attia, J., Whitfield, J. B., Chalmers, J., Viikari, J., Coresh, J., Denny, J. C., Karjalainen, J., Fernandes, J. K., Endlich, K., Butterbach, K., Keene, K. L., Lohman, K., Portas, L., Launer, L. J., Lyytikäinen, L. P., Yengo, L., Franke, L., Ferrucci, L., Rose, L. M., Kedenko, L., Rao, M., Struchalin, M., Kleber, M. E., Cavalieri, M., Haun, M., Cornelis, M. C., Ciullo, M., Pirastu, M., De Andrade, M., McEvoy, M. A., Woodward, M., Adam, M., Cocca, M., Nauck, M., Imboden, M., Waldenberger, M., Pruijm, M., Metzger, M., Stumvoll, M., Evans, M. K., Sale, M. M., Kähönen, M., Boban, M., Bochud, M., Rheinberger, M., Verweij, N., Bouatia-Naji, N., Martin, N. G., Hastie, N., Probst-Hensch, N., Soranzo, N., Devuyst, O., Raitakari, O., Gottesman, O., Franco, O. H., Polasek, O., Gasparini, P., Munroe, P. B., Ridker, P. M., Mitchell, P., Muntner, P., Meisinger, C., Smit, J. H., Abecasis, G. R., Adair, L. S., Alexander, M., Altshuler, D., Amin, N., Arking, D. E., Arora, P., Aulchenko, Y., Bakker, S. J. L., Bandinelli, S., Barroso, I., Beckmann, J. S., Beilby, J. P., Bergman, R. N., Bergmann, S., Bis, J. C., Boehnke, M., Bonnycastle, L. L., Bornstein, S. R., Bots, M. L., Bragg-Gresham, J. L., Brand, S. M., Brand, E., Braund, P. S., Brown, M. J., Burton, P. R., Casas, J. P., Caulfield, M. J., Chakravarti, A., Chambers, J. C., Chandak, G. R., Chang, Y. P. C., Charchar, F. J., Chaturvedi, N., Cho, Y. S., Clarke, R., Collins, F. S., Collins, R., Connell, J. M., Cooper, J. A., Cooper, M. N., Cooper, R. S., Corsi, A. M., Dörr, M., Dahgam, S., Danesh, J., Smith, G. D., Day, I. N. M., Deloukas, P., Denniff, M., Dominiczak, A. F., Dong, Y., Doumatey, A., Elliott, P., Elosua, R., Erdmann, J., Eyheramendy, S., Farrall, M., Fava, C., Forrester, T., Fowkes, F. G. R., Fox, E. R., Frayling, T. M., Galan, P., Ganesh, S. K., Garcia, M., Gaunt, T. R., Glazer, N. L., Go, M. J., Goel, A., Grässler, J., Grobbee, D. E., Groop, L., Guarrera, S., Guo, X., Hadley, D., Hamsten, A., Han, B. G., Hardy, R., Hartikainen, A. L., Heath, S., Heckbert, S. R., Hedblad, B., Hercberg, S., Hernandez, D., Hicks, A. A., Hilton, G., Hingorani, A. D., Hoffman Bolton, J. A., Hopewell, J. C., Howard, P., Humphries, S. E., Hunt, S. C., Hveem, K., Ikram, M. A., Islam, M., Iwai, N., Jarvelin, M. R., Jackson, A. U., Jafar, T. H., Janipalli, C. S., Johnson, T., Kathiresan, S., Khaw, K. T., Kim, H. L., Kinra, S., Kita, Y., Kivimaki, M., Kooner, J. S., Kumar, M. J. K., Kuh, D., Kulkarni, S. R., Kumari, M., Kuusisto, J., Kuznetsova, T., Laakso, M., Laan, M., Laitinen, J., Lakatta, E. G., Langefeld, C. D., Larson, M. G., Lathrop, M., Lawlor, D. A., Lawrence, R. W., Lee, J. Y., Lee, N. R., Levy, D., Li, Y., Longstreth, W. T., Luan, J., Lucas, G., Ludwig, B., Mangino, M., Mani, K. R., Marmot, M. G., Mattace-Raso, F. U. S., Matullo, G., McArdle, W. L., McKenzie, C. A., Meitinger, T., Melander, O., Meneton, P., Meschia, J. F., Miki, T., Milaneschi, Y., Mohlke, K. L., Mooser, V., Morken, M. A., Morris, R. W., Mosley, T. H., Najjar, S., Narisu, N., Newton-Cheh, C., Nguyen, K. D. H., Nilsson, P., Nyberg, F., O'Donnell, C. J., Ogihara, T., Ohkubo, T., Okamura, T., Ong, R. T. H., Ongen, H., Onland-Moret, N. C., O'Reilly, P. F., Org, E., Orru, M., Palmas, W., Palmen, J., Palmer, L. J., Palmer, N. D., Parker, A. N., Peden, J. F., Peltonen, L., Perola, M., Pihur, V., Platou, C. G. P., Plump, A., Prabhakaran, D., Psaty, B. M., Raffel, L. J., Rao, D. C., Rasheed, A., Ricceri, F., Rice, K. M., Rosengren, A., Rotter, J. I., Rudock, M. E., Sõber, S., Salako, T., Saleheen, D., Salomaa, V., Samani, N. J., Schwartz, S. M., Schwarz, P. E. H., Scott, L. J., Scott, J., Scuteri, A., Sehmi, J. S., Seielstad, M., Seshadri, S., Sharma, P., Shaw-Hawkins, S., Shi, G., Shrine, N. R. G., Sijbrands, E. J. G., Sim, X., Singleton, A., Sjögren, M., Smith, N. L., Artigas, M. S., Spector, T. D., Staessen, J. A., Stancakova, A., Steinle, N. I., Strachan, D. P., Stringham, H. M., Sun, Y. V., Swift, A. J., Tabara, Y., Tai, E. S., Talmud, P. J., Taylor, A., Terzic, J., Thelle, D. S., Tobin, M. D., Tomaszewski, M., Tripathy, V., Tuomilehto, J., Tzoulaki, I., Uda, M., Ueshima, H., Uiterwaal, C. S. P. M., Umemura, S., Van Der Harst, P., Van Der Schouw, Y. T., Van Gilst, W. H., Vartiainen, E., Vasan, R. S., Veldre, G., Verwoert, G. C., Viigimaa, M., Vinay, D. G., Vineis, P., Voight, B. F., Vollenweider, P., Wagenknecht, L. E., Wain, L. V., Wang, X., Wang, T. J., Wareham, N. J., Watkins, H., Weder, A. B., Whincup, P. H., Wiggins, K. L., Witteman, J. C. M., Wong, A., Wu, Y., Yajnik, C. S., Yao, J., Young, J. H., Zelenika, D., Zhai, G., Zhang, W., Zhang, F., Zhao, J. H., Zhu, H., Zhu, X., Zitting, P., Zukowska-Szczechowska, E., Okada, Y., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Teo, Y. Y., Kim, Y. J., Kang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J. C., Mei, H., Hixson, J. E., Chen, S., Katsuya, T., Isono, M., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y. T., Tanaka, T., Reilly, M. P., Schunkert, H., Assimes, T. L., Hall, A., Hengstenberg, C., König, I. R., Laaksonen, R., McPherson, R., Thompson, J. R., Thorsteinsdottir, U., Ziegler, A., Absher, D., Chen, L., Cupples, L. A., Halperin, E., Li, M., Musunuru, K., Preuss, M., Schillert, A., Thorleifsson, G., Wells, G. A., Holm, H., Roberts, R., Stewart, A. F. R., Fortmann, S., Go, A., Hlatky, M., Iribarren, C., Knowles, J., Myers, R., Quertermous, T., Sidney, S., Risch, N., Tang, H., Blankenberg, S., Schnabel, R., Sinning, C., Lackner, K. J., Tiret, L., Nicaud, V., Cambien, F., Bickel, C., Rupprecht, H. J., Perret, C., Proust, C., Münzel, T. F., Barbalic, M., Chen, I. Y. D., Demissie-Banjaw, S., Folsom, A., Lumley, T., Marciante, K., Taylor, K. D., Volcik, K., Gretarsdottir, S., Gulcher, J. R., Kong, A., Stefansson, K., Thorgeirsson, G., Andersen, K., Fischer, M., Grosshennig, A., Linsel-Nitschke, P., Stark, K., Schreiber, S., Aherrahrou, Z., Bruse, P., Doering, A., Klopp, N., Diemert, P., Loley, C., Medack, A., Nahrstedt, J., Peters, A., Wagner, A. K., Willenborg, C., Böhm, B. O., Dobnig, H., Grammer, T. B., Hoffmann, M. M., Meinitzer, A., Winkelmann, B. R., Pilz, S., Renner, W., Scharnagl, H., Stojakovic, T., Tomaschitz, A., Winkler, K., Guiducci, C., Burtt, N., Gabriel, S. B., Dandona, S., Jarinova, O., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Devaney, J., Burnett, M. S., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Knouff, C. W., Waterworth, D. M., Walker, M. C., Epstein, S. E., Rader, D. J., Nelson, C. P., Wright, B. J., Balmforth, A. J., Ball, S. G., Loehr, L. R., Rosamond, W. D., Benjamin, E., Haritunians, T., Couper, D., Murabito, J., Wang, Y. A., Stricker, B. H., Chang, P. P., Willerson, J. T., Felix, S. B., Watzinger, N., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R. J., Greiser, K. H., Deckers, J. W., Stritzke, J., Ingelsson, E., Kullo, I., Haerting, J., Reffelmann, T., Redfield, M. M., Werdan, K., Mitchell, G. F., Arnett, D. K., Gottdiener, J. S., Blettner, M., Friedrich, N., Kovacs, P., Wild, P. S., Froguel, P., Rettig, R., Mägi, R., Biffar, R., Schmidt, R., Middelberg, R. P. S., Carroll, R. J., Penninx, B. W., Scott, R. J., Katz, R., Sedaghat, S., Wild, S. H., Kardia, S. L. R., Ulivi, S., Hwang, S. J., Enroth, S., Kloiber, S., Trompet, S., Stengel, B., Hancock, S. J., Turner, S. T., Rosas, S. E., Stracke, S., Harris, T. B., Zeller, T., Zemunik, T., Lehtimäki, T., Illig, T., Aspelund, T., Nikopensius, T., Esko, T., Tanaka, T., Gyllensten, U., Völker, U., Emilsson, V., Vitart, V., Aalto, V., Gudnason, V., Chouraki, V., Chen, W. M., Igl, W., März, W., Koenig, W., Lieb, W., Loos, R. J. F., Liu, Y., Snieder, H., Pramstaller, P. P., Parsa, A., O'Connell, J. R., Susztak, K., Hamet, P., Tremblay, J., De Boer, I. H., Böger, C. A., Goessling, W., Chasman, D. I., Köttgen, A., Kao, W. H. L. & Fox, C. S., 21-01-2016, In : Nature communications. 7, 10023.

Research output: Contribution to journalArticle

192 Citations (Scopus)

Genetic characteristics of inflammatory bowel disease in a Japanese population

Fuyuno, Y., Yamazaki, K., Takahashi, A., Esaki, M., Kawaguchi, T., Takazoe, M., Matsumoto, T., Matsui, T., Tanaka, H., Motoya, S., Suzuki, Y., Kiyohara, Y., Kitazono, T. & Kubo, M., 01-07-2016, In : Journal of Gastroenterology. 51, 7, p. 672-681 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Genetic polymorphisms in the long noncoding RNA MIR2052HG offer a pharmacogenomic basis for the response of breast cancer patients to aromatase inhibitor therapy

Ingle, J. N., Xie, F., Ellis, M. J., Goss, P. E., Shepherd, L. E., Chapman, J. A. W., Chen, B. E., Kubo, M., Furukawa, Y., Momozawa, Y., Stearns, V., Pritchard, K. I., Barman, P., Carlson, E. E., Goetz, M. P., Weinshilboum, R. M., Kalari, K. R. & Wang, L., 01-12-2016, In : Cancer Research. 76, 23, p. 7012-7023 12 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Genetic risk score based on the prevalence of vertebral fracture in Japanese women with osteoporosis

Zhou, H., Mori, S., Ishizaki, T., Takahashi, A., Matsuda, K., Koretsune, Y., Minami, S., Higashiyama, M., Imai, S., Yoshimori, K., Doita, M., Yamada, A., Nagayama, S., Kaneko, K., Asai, S., Shiono, M., Kubo, M. & Ito, H., 01-12-2016, In : Bone Reports. 5, p. 168-172 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Genetic Variation in the SLC8A1 Calcium Signaling Pathway Is Associated with Susceptibility to Kawasaki Disease and Coronary Artery Abnormalities

Shimizu, C., Eleftherohorinou, H., Wright, V. J., Kim, J., Alphonse, M. P., Perry, J. C., Cimaz, R., Burgner, D., Dahdah, N., Hoang, L. T., Khor, C. C., Salgado, A., Tremoulet, A. H., Davila, S., Kuijpers, T. W., Hibberd, M. L., Johnson, T. A., Takahashi, A., Tsunoda, T., Kubo, M. & 6 others, Tanaka, T., Onouchi, Y., Yeung, R. S. M., Coin, L. J. M., Levin, M. & Burns, J. C., 01-12-2016, In : Circulation: Cardiovascular Genetics. 9, 6, p. 559-568 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity

Petros, Z., Lee, M. T. M., Takahashi, A., Zhang, Y., Yimer, G., Habtewold, A., Amogne, W., Aderaye, G., Schuppe-Koistinen, I., Mushiroda, T., Makonnen, E., Kubo, M. & Aklillu, E., 26-09-2016, In : BMC Genomics. 17, 1, 755.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Genomewide Association Studies in Pharmacogenomics: Meeting Report of the NIH Pharmacogenomics Research Network-RIKEN (PGRN-RIKEN) Collaboration

Yee, S. W., Momozawa, Y., Kamatani, Y., Tyndale, R. F., Weinshilboum, R. M., Ratain, M. J., Giacomini, K. M. & Kubo, M., 01-11-2016, In : Clinical Pharmacology and Therapeutics. p. 423-426 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

Imamura, M., Takahashi, A., Yamauchi, T., Hara, K., Yasuda, K., Grarup, N., Zhao, W., Wang, X., Huerta-Chagoya, A., Hu, C., Moon, S., Long, J., Kwak, S. H., Rasheed, A., Saxena, R., Ma, R. C. W., Okada, Y., Iwata, M., Hosoe, J., Shojima, N. & 43 others, Iwasaki, M., Fujita, H., Suzuki, K., Danesh, J., Jørgensen, T., Jørgensen, M. E., Witte, D. R., Brandslund, I., Christensen, C., Hansen, T., Mercader, J. M., Flannick, J., Moreno-Macías, H., Burtt, N. P., Zhang, R., Kim, Y. J., Zheng, W., Singh, J. R., Tam, C. H. T., Hirose, H., Maegawa, H., Ito, C., Kaku, K., Watada, H., Tanaka, Y., Tobe, K., Kawamori, R., Kubo, M., Cho, Y. S., Chan, J. C. N., Sanghera, D., Frossard, P., Park, K. S., Shu, X. O., Kim, B. J., Florez, J. C., Tusié-Luna, T., Jia, W., Tai, E. S., Pedersen, O., Saleheen, D., Maeda, S. & Kadowaki, T., 28-01-2016, In : Nature communications. 7, 10531.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Genome-wide association studies of drug response and toxicity: An opportunity for genome medicine

Giacomini, K. M., Yee, S. W., Mushiroda, T., Weinshilboum, R. M., Ratain, M. J. & Kubo, M., 29-12-2016, In : Nature Reviews Drug Discovery. 16, 1, 1 p.

Research output: Contribution to journalLetter

36 Citations (Scopus)

Genome-wide association study in East Asians identifies two novel breast cancer susceptibility loci

Han, M. R., Long, J., Choi, J. Y., Low, S. K., Kweon, S. S., Zheng, Y., Cai, Q., Shi, J., Guo, X., Matsuo, K., Iwasaki, M., Shen, C. Y., Kim, M. K., Wen, W., Li, B., Takahashi, A., Shin, M. H., Xiang, Y. B., Ito, H., Kasuga, Y. & 11 others, Noh, D. Y., Matsuda, K., Park, M. H., Gao, Y. T., Iwata, H., Tsugane, S., Park, S. K., Kubo, M., Shu, X. O., Kang, D. & Zheng, W., 01-01-2016, In : Human molecular genetics. 25, 15, p. 3361-3371 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Genome-wide association study of clinically defined Gout identifies multiple risk loci and its association with clinical subtypes

Matsuo, H., Yamamoto, K., Nakaoka, H., Nakayama, A., Sakiyama, M., Chiba, T., Takahashi, A., Nakamura, T., Nakashima, H., Takada, Y., Danjoh, I., Shimizu, S., Abe, J., Kawamura, Y., Terashige, S., Ogata, H., Tatsukawa, S., Yin, G., Okada, R., Morita, E. & 20 others, Naito, M., Tokumasu, A., Onoue, H., Iwaya, K., Ito, T., Takada, T., Inoue, K., Kato, Y., Nakamura, Y., Sakurai, Y., Suzuki, H., Kanai, Y., Hosoya, T., Hamajima, N., Inoue, I., Kubo, M., Ichida, K., Ooyama, H., Shimizu, T. & Shinomiya, N., 04-2016, In : Annals of the Rheumatic Diseases. 75, 4, p. 652-659 8 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Genome-wide association study of leukotriene modifier response in asthma

Dahlin, A., Litonjua, A., Irvin, C. G., Peters, S. P., Lima, J. J., Kubo, M., Tamari, M. & Tantisira, K. G., 01-04-2016, In : Pharmacogenomics Journal. 16, 2, p. 151-157 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Genome-wide environment interaction between depressive state and stressful life events

Ikeda, M., Shimasaki, A., Takahashi, A., Kondo, K., Saito, T., Kawase, K., Esaki, K., Otsuka, Y., Mano, K., Kubo, M. & Iwata, N., 01-2016, In : Journal of Clinical Psychiatry. 77, 1, p. e29-e30

Research output: Contribution to journalLetter

12 Citations (Scopus)

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

Sun, C., Molineros, J. E., Looger, L. L., Zhou, X. J., Kim, K., Okada, Y., Ma, J., Qi, Y. Y., Kim-Howard, X., Motghare, P., Bhattarai, K., Adler, A., Bang, S. Y., Lee, H. S., Kim, T. H., Kang, Y. M., Suh, C. H., Chung, W. T., Park, Y. B., Choe, J. Y. & 18 others, Shim, S. C., Kochi, Y., Suzuki, A., Kubo, M., Sumida, T., Yamamoto, K., Lee, S. S., Kim, Y. J., Han, B. G., Dozmorov, M., Kaufman, K. M., Wren, J. D., Harley, J. B., Shen, N., Chua, K. H., Zhang, H., Bae, S. C. & Nath, S. K., 01-03-2016, In : Nature Genetics. 48, 3, p. 323-330 8 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)

High prevalence of G12 human rotaviruses in children with gastroenteritis in Myanmar

Ide, T., Higo-Moriguchi, K., Komoto, S., Htun, K. W., Myint, Y. Y., Myat, T. W., Thant, K. Z., Thu, H. M., Win, M. M., Oo, H. N., Htut, T., Rahman, S., Van Nguyen, S., Umeda, K., Oguma, K., Tsuji, T. & Taniguchi, K., 01-01-2016, In : Japanese journal of infectious diseases. 69, 4, p. 326-327 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Hippocampus-dependent spatial memory impairment due to molar tooth loss is ameliorated by an enriched environment

Kondo, H., Kurahashi, M., Mori, D., Iinuma, M., Tamura, Y., Mizutani, K., Shimpo, K., Sonoda, S., Azuma, K. & Kubo, K. Y., 01-2016, In : Archives of Oral Biology. 61, p. 1-7 7 p., 3473.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans

Lee, S. A., Mefford, J. A., Huang, Y., Witte, J. S., Martin, J. N., Haas, D. W., McLaren, P. J., Mushiroda, T., Kubo, M., Byakwaga, H., Hunt, P. W. & Kroetz, D. L., 17-07-2016, In : AIDS. 30, 11, p. 1807-1815 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Hyaluronan production regulates metabolic and cancer stem-like properties of breast cancer cells via hexosamine biosynthetic pathway-coupled HIF-1 signaling

Chanmee, T., Ontong, P., Izumikawa, T., Higashide, M., Mochizuki, N., Chokchaitaweesuk, C., Khansai, M., Nakajima, K., Kakizaki, I., Kongtawelert, P., Taniguchi, N. & Itano, N., 11-11-2016, In : Journal of Biological Chemistry. 291, 46, p. 24105-24120 16 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk

Zeng, C., Matsuda, K., Jia, W. H., Chang, J., Kweon, S. S., Xiang, Y. B., Shin, A., Jee, S. H., Kim, D. H., Zhang, B., Cai, Q., Guo, X., Long, J., Wang, N., Courtney, R., Pan, Z. Z., Wu, C., Takahashi, A., Shin, M. H., Matsuo, K. & 87 others, Matsuda, F., Gao, Y. T., Oh, J. H., Kim, S., Jung, K. J., Ahn, Y. O., Ren, Z., Li, H. L., Wu, J., Shi, J., Wen, W., Yang, G., Li, B., Ji, B. T., Gruber, S. B., Schumacher, F. R., Stenzel, S. L., Casey, G., Hopper, J. L., Jenkins, M. A., Kim, H. R., Jeong, J. Y., Park, J. W., Tajima, K., Cho, S. H., Kubo, M., Shu, X. O., Lin, D., Zeng, Y. X., Zheng, W., Brenner, H., Schoen, R. E., Küry, S., Baron, J. A., Berndt, S. I., Bezieau, S., Caan, B. J., Carlson, C. S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Conti, D. V., Curtis, K., Duggan, D., Fuchs, C. S., Gallinger, S., Giovannucci, E. L., Haile, R. W., Harrison, T. A., Hayes, R. B., Hoffmeister, M., Hsu, L., Hudson, T. J., Hunter, D. J., Hutter, C. M., Jackson, R. D., Jiao, S., Le Marchand, L., Lemire, M., Lindor, N. M., Ma, J., Newcomb, P. A., Peters, U., Potter, J. D., Qu, C., Seminara, D., Slattery, M. L., Thibodeau, S. N., White, E., Zanke, B. W., Blalock, K., Campbell, P. T., Edlund, C. K., Figueiredo, J., Gauderman, W. J., Gong, J., Green, R. C., Harju, J. F., Jacobs, E. J., Li, L., Lin, Y., Manion, F. J., Moreno, V., Mukherjee, B., Raskin, L., Severi, G. & Thomas, D. C., 01-06-2016, In : Gastroenterology. 150, 7, p. 1633-1645 13 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Induction of HLA-B*40:02-restricted T cells possessing cytotoxic and suppressive functions against haematopoietic progenitor cells from a patient with severe aplastic anaemia

Inaguma, Y., Akatsuka, Y., Hosokawa, K., Maruyama, H., Okamoto, A., Katagiri, T., Shiraishi, K., Murayama, Y., Tsuzuki-Iba, S., Mizutani, Y., Nishii, C., Yamamoto, N., Demachi-Okamura, A., Kuzushima, K., Ogawa, S., Emi, N. & Nakao, S., 01-01-2016, In : British Journal of Haematology. 172, 1, p. 131-134 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)