Research Promotion and Support Headquarters

Research Output

2017

Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population

Terao, C., Okada, Y., Ikari, K., Kochi, Y., Suzuki, A., Ohmura, K., Matsuo, K., Taniguchi, A., Kubo, M., Raychaudhuri, S., Yamamoto, K., Yamanaka, H., Kamatani, Y., Mimori, T. & Matsuda, F., 01-12-2017, In : Journal of Medical Genetics. 54, 12, p. 853-858 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Genetic Predisposition to Ischemic Stroke: A Polygenic Risk Score

Hachiya, T., Kamatani, Y., Takahashi, A., Hata, J., Furukawa, R., Shiwa, Y., Yamaji, T., Hara, M., Tanno, K., Ohmomo, H., Ono, K., Takashima, N., Matsuda, K., Wakai, K., Sawada, N., Iwasaki, M., Yamagishi, K., Ago, T., Ninomiya, T., Fukushima, A. & 21 others, Hozawa, A., Minegishi, N., Satoh, M., Endo, R., Sasaki, M., Sakata, K., Kobayashi, S., Ogasawara, K., Nakamura, M., Hitomi, J., Kita, Y., Tanaka, K., Iso, H., Kitazono, T., Kubo, M., Tanaka, H., Tsugane, S., Kiyohara, Y., Yamamoto, M., Sobue, K. & Shimizu, A., 01-02-2017, In : Stroke. 48, 2, p. 253-258 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Genetic variants associated with uncontrolled blood pressure on thiazide diuretic/β-blocker combination therapy in the PEAR (Pharmacogenomic Evaluation Of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) trials

Magvanjav, O., Gong, Y., McDonough, C. W., Chapman, A. B., Turner, S. T., Gums, J. G., Bailey, K. R., Boerwinkle, E., Beitelshees, A. L., Tanaka, T., Kubo, M., Pepine, C. J., Cooper-DeHoff, R. M. & Johnson, J. A., 01-11-2017, In : Journal of the American Heart Association. 6, 11, e006522.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Genetic variants of RAMP2 and CLR are associated with stroke

Koyama, T., Kuriyama, N., Ozaki, E., Matsui, D., Watanabe, I., Takeshita, W., Iwai, K., Watanabe, Y., Nakatochi, M., Shimanoe, C., Tanaka, K., Oze, I., Ito, H., Uemura, H., Katsuura-Kamano, S., Ibusuki, R., Shimoshikiryo, I., Takashima, N., Kadota, A., Kawai, S. & 14 others, Sasakabe, T., Okada, R., Hishida, A., Naito, M., Kuriki, K., Endoh, K., Furusyo, N., Ikezaki, H., Suzuki, S., Hosono, A., Mikami, H., Nakamura, Y., Kubo, M. & Wakai, K., 2017, In : Journal of atherosclerosis and thrombosis. 24, 12, p. 1267-1281 15 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs

Petros, Z., Lee, M. T. M., Takahashi, A., Zhang, Y., Yimer, G., Habtewold, A., Schuppe-Koistinen, I., Mushiroda, T., Makonnen, E., Kubo, M. & Aklillu, E., 04-2017, In : OMICS A Journal of Integrative Biology. 21, 4, p. 207-216 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Genome-wide association study identifies 112 new loci for body mass index in the Japanese population

Akiyama, M., Okada, Y., Kanai, M., Takahashi, A., Momozawa, Y., Ikeda, M., Iwata, N., Ikegawa, S., Hirata, M., Matsuda, K., Iwasaki, M., Yamaji, T., Sawada, N., Hachiya, T., Tanno, K., Shimizu, A., Hozawa, A., Minegishi, N., Tsugane, S., Yamamoto, M. & 2 others, Kubo, M. & Kamatani, Y., 01-10-2017, In : Nature Genetics. 49, 10, p. 1458-1467 10 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)

Genome-wide Association Study of Idiopathic Osteonecrosis of the Femoral Head

Sakamoto, Y., Yamamoto, T., Sugano, N., Takahashi, D., Watanabe, T., Atsumi, T., Nakamura, J., Hasegawa, Y., Akashi, K., Narita, I., Miyamoto, T., Takeuchi, T., Ikari, K., Amano, K., Fujie, A., Kubo, T., Tada, Y., Kaneuji, A., Nakamura, H., Miyamura, T. & 70 others, Kabata, T., Yamaji, K., Okawa, T., Sudo, A., Ohzono, K., Tanaka, Y., Yasunaga, Y., Matsuda, S., Imai, Y., Nakashima, Y., Motomura, G., Ikemura, S., Yamaguchi, R., Karasuyama, K., Sonoda, K., Nishii, T., Sakai, T., Takao, M., Irie, T., Asano, T., Iwasaki, N., Atsumi, T., Tamaoki, S., Nakanishi, R., Tanabe, S., Kishida, S., Hagiwara, S., Seki, T., Tsukamoto, H., Niiro, H., Arinobu, Y., Akahoshi, M., Mitoma, H., Ayano, M., Kuroda, T., Toyama, Y., Funayama, A., Hanaoka, H., Yamaoka, K., Kawaguchi, Y., Yamanaka, H., Hosozawa, T., Momohara, S., Chino, K., Fujioka, M., Ueshima, K., Ishida, M., Saito, M., Hayashi, S., Ikegami, A., Ichiseki, T., Mizokawa, S., Ohta, Y., Kajino, Y., Sekiya, F., Higuchi, F., Hasegawa, M., Miyamoto, N., Miyazaki, S., Yamaguchi, T., Ando, W., Saito, K., Nakano, K., Kuroda, Y., Yamasaki, T., Akiyama, M., Kubo, M., Kamatani, Y., Iwamoto, Y. & Ikegawa, S., 01-12-2017, In : Scientific reports. 7, 1, 15035.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Genome-wide association study of neovascular age-related macular degeneration in the Thai population

Ruamviboonsuk, P., Tadarati, M., Singhanetr, P., Wattanapokayakit, S., Kunhapan, P., Wanitchanon, T., Wichukchinda, N., Mushiroda, T., Akiyama, M., Momozawa, Y., Kubo, M. & Mahasirimongkol, S., 01-11-2017, In : Journal of Human Genetics. 62, 11, p. 957-962 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

van Rooij, F. J. A., Qayyum, R., Smith, A. V., Zhou, Y., Trompet, S., Tanaka, T., Keller, M. F., Chang, L. C., Schmidt, H., Yang, M. L., Chen, M. H., Hayes, J., Johnson, A. D., Yanek, L. R., Mueller, C., Lange, L., Floyd, J. S., Ghanbari, M., Zonderman, A. B., Jukema, J. W. & 80 others, Hofman, A., van Duijn, C. M., Desch, K. C., Saba, Y., Ozel, A. B., Snively, B. M., Wu, J. Y., Schmidt, R., Fornage, M., Klein, R. J., Fox, C. S., Matsuda, K., Kamatani, N., Wild, P. S., Stott, D. J., Ford, I., Slagboom, P. E., Yang, J., Chu, A. Y., Lambert, A. J., Uitterlinden, A. G., Franco, O. H., Hofer, E., Ginsburg, D., Hu, B., Keating, B., Schick, U. M., Brody, J. A., Li, J. Z., Chen, Z., Zeller, T., Guralnik, J. M., Chasman, D. I., Peters, L. L., Kubo, M., Becker, D. M., Li, J., Eiriksdottir, G., Rotter, J. I., Levy, D., Grossmann, V., Patel, K. V., Chen, C. H., Ridker, P. M., Tang, H., Launer, L. J., Rice, K. M., Li-Gao, R., Ferrucci, L., Evans, M. K., Choudhuri, A., Trompouki, E., Abraham, B. J., Yang, S., Takahashi, A., Kamatani, Y., Kooperberg, C., Harris, T. B., Jee, S. H., Coresh, J., Tsai, F. J., Longo, D. L., Chen, Y. T., Felix, J. F., Yang, Q., Psaty, B. M., Boerwinkle, E., Becker, L. C., Mook-Kanamori, D. O., Wilson, J. G., Gudnason, V., O'Donnell, C. J., Dehghan, A., Cupples, L. A., Nalls, M. A., Morris, A. P., Okada, Y., Reiner, A. P., Zon, L. I. & Ganesh, S. K., 05-01-2017, In : American Journal of Human Genetics. 100, 1, p. 51-63 13 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes

Nakayama, A., Nakaoka, H., Yamamoto, K., Sakiyama, M., Shaukat, A., Toyoda, Y., Okada, Y., Kamatani, Y., Nakamura, T., Takada, T., Inoue, K., Yasujima, T., Yuasa, H., Shirahama, Y., Nakashima, H., Shimizu, S., Higashino, T., Kawamura, Y., Ogata, H., Kawaguchi, M. & 26 others, Ohkawa, Y., Danjoh, I., Tokumasu, A., Ooyama, K., Ito, T., Kondo, T., Wakai, K., Stiburkova, B., Pavelka, K., Stamp, L. K., Dalbeth, N., Sakurai, Y., Suzuki, H., Hosoyamada, M., Fujimori, S., Yokoo, T., Hosoya, T., Inoue, I., Takahashi, A., Kubo, M., Ooyama, H., Shimizu, T., Ichida, K., Shinomiya, N., Merriman, T. R. & Matsuo, H., 01-05-2017, In : Annals of the Rheumatic Diseases. 76, 5, p. 869-877 9 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Hierarchical Maximum Likelihood Clustering Approach

Sharma, A., Boroevich, K. A., Shigemizu, D., Kamatani, Y., Kubo, M. & Tsunoda, T., 01-2017, In : IEEE Transactions on Biomedical Engineering. 64, 1, p. 112-122 11 p., 7440832.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Identification and characterization of a human G9P[23] rotavirus strain from a child with diarrhoea in Thailand: Evidence for porcine-to-human interspecies transmission

Komoto, S., Tacharoenmuang, R., Guntapong, R., Ide, T., Sinchai, P., Upachai, S., Fukuda, S., Yoshikawa, T., Tharmaphornpilas, P., Sangkitporn, S. & Taniguchi, K., 04-2017, In : Journal of General Virology. 98, 4, p. 532-538 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Identification of novel splicing variants of protein tyrosine phosphatase receptor type Z

Fujikawa, A., Chow, J. P. H., Matsumoto, M., Suzuki, R., Kuboyama, K., Yamamoto, N. & Noda, M., 01-01-2017, In : Journal of Biochemistry. 162, 5, p. 381-390 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Identification of six new genetic loci associated with atrial fibrillation in the Japanese population

Low, S. K., Takahashi, A., Ebana, Y., Ozaki, K., Christophersen, I. E., Ellinor, P. T., Ogishima, S., Yamamoto, M., Satoh, M., Sasaki, M., Yamaji, T., Iwasaki, M., Tsugane, S., Tanaka, K., Naito, M., Wakai, K., Tanaka, H., Furukawa, T., Kubo, M., Ito, K. & 2 others, Kamatani, Y. & Tanaka, T., 01-06-2017, In : Nature Genetics. 49, 6, p. 953-958 6 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Increased airway hyperresponsiveness to adenosine in patients with aspirin intolerant asthma

Isogai, S., Niwa, Y., Yatsuya, H., Hayashi, M., Yamamoto, N., Okamura, T., Minezawa, T., Goto, Y., Yamaguchi, T., Takeyama, T., Sakakibara, Y., Morikawa, S., Horiguchi, T., Gotoh, Y., Mieno, Y., Uozu, S., Nakanishi, T., Okazawa, M., Sakakibara, H. & Imaizumi, K., 01-04-2017, In : Allergology International. 66, 2, p. 360-362 3 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)

Induced pluripotent stem cells: Global research trends

Negoro, T., Okura, H. & Matsuyama, A., 05-2017, In : BioResearch Open Access. 6, 1, p. 63-73 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression

Kasai, S., Furuichi, Y., Ando, N., Kagami, K., Abe, M., Nakane, T., Goi, K., Inukai, T., Saitoh, S., Ohno, S., Okazaki, S., Nagano, O., Saya, H. & Sugita, K., 01-06-2017, In : Cell death & disease. 8, 6, p. e2857

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Christophersen, I. E., Rienstra, M., Roselli, C., Yin, X., Geelhoed, B., Barnard, J., Lin, H., Arking, D. E., Smith, A. V., Albert, C. M., Chaffin, M., Tucker, N. R., Li, M., Klarin, D., Bihlmeyer, N. A., Low, S. K., Weeke, P. E., Müller-Nurasyid, M., Smith, J. G., Brody, J. A. & 142 others, Niemeijer, M. N., Dörr, M., Trompet, S., Huffman, J., Gustafsson, S., Schurmann, C., Kleber, M. E., Lyytikäinen, L. P., Seppälä, I., Malik, R., Horimoto, A. R. V. R., Perez, M., Sinisalo, J., Aeschbacher, S., Thériault, S., Yao, J., Radmanesh, F., Weiss, S., Teumer, A., Choi, S. H., Weng, L. C., Clauss, S., Deo, R., Rader, D. J., Shah, S. H., Sun, A., Hopewell, J. C., Debette, S., Chauhan, G., Yang, Q., Worrall, B. B., Paré, G., Kamatani, Y., Hagemeijer, Y. P., Verweij, N., Siland, J. E., Kubo, M., Smith, J. D., Van Wagoner, D. R., Bis, J. C., Perz, S., Psaty, B. M., Ridker, P. M., Magnani, J. W., Harris, T. B., Launer, L. J., Shoemaker, M. B., Padmanabhan, S., Haessler, J., Bartz, T. M., Waldenberger, M., Lichtner, P., Arendt, M., Krieger, J. E., Kähönen, M., Risch, L., Mansur, A. J., Peters, A., Smith, B. H., Lind, L., Scott, S. A., Lu, Y., Bottinger, E. B., Hernesniemi, J., Lindgren, C. M., Wong, J. A., Huang, J., Eskola, M., Morris, A. P., Ford, I., Reiner, A. P., Delgado, G., Chen, L. Y., Chen, Y. D. I., Sandhu, R. K., Li, M., Boerwinkle, E., Eisele, L., Lannfelt, L., Rost, N., Anderson, C. D., Taylor, K. D., Campbell, A., Magnusson, P. K., Porteous, D., Hocking, L. J., Vlachopoulou, E., Pedersen, N. L., Nikus, K., Orho-Melander, M., Hamsten, A., Heeringa, J., Denny, J. C., Kriebel, J., Darbar, D., Newton-Cheh, C., Shaffer, C., Macfarlane, P. W., Heilmann-Heimbach, S., Almgren, P., Huang, P. L., Sotoodehnia, N., Soliman, E. Z., Uitterlinden, A. G., Hofman, A., Franco, O. H., Völker, U., Jöckel, K. H., Sinner, M. F., Lin, H. J., Guo, X., Dichgans, M., Ingelsson, E., Kooperberg, C., Melander, O., Loos, R. J. F., Laurikka, J., Conen, D., Rosand, J., Van Der Harst, P., Lokki, M. L., Kathiresan, S., Pereira, A., Jukema, J. W., Hayward, C., Rotter, J. I., März, W., Lehtimäki, T., Stricker, B. H., Chung, M. K., Felix, S. B., Gudnason, V., Alonso, A., Roden, D. M., Kääb, S., Chasman, D. I., Heckbert, S. R., Benjamin, E. J., Tanaka, T., Lunetta, K. L., Lubitz, S. A. & Ellinor, P. T., 01-06-2017, In : Nature Genetics. 49, 6, p. 946-952 7 p.

Research output: Contribution to journalArticle

108 Citations (Scopus)

Ligation-mediated PCR with a back-to-back adapter reduces amplification bias resulting from variations in GC content

Ishihara, S., Kotomura, N., Yamamoto, N. & Ochiai, H., 15-08-2017, In : Analytical Biochemistry. 531, p. 37-44 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Macronutrient intakes and serum oestrogen, and interaction with polymorphisms in CYP19A1 and HSD17B1 genes: A cross-sectional study in postmenopausal Japanese women

Takagi, S., Naito, M., Kawai, S., Okada, R., Nagata, C., Hosono, S., Nishida, Y., Takashima, N., Suzuki, S., Shimoshikiryo, I., Mikami, H., Uemura, H., Kuriyama, N., Ohnaka, K., Kubo, M., Hamajima, N., Tanaka, H. & Wakai, K., 28-09-2017, In : British Journal of Nutrition. 118, 6, p. 463-472 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer

The Japan Multi-institutional Collaborative Cohort Study Group, 01-03-2017, In : Gastric Cancer. 20, 2, p. 246-253 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

Sapkota, Y., Steinthorsdottir, V., Morris, A. P., Fassbender, A., Rahmioglu, N., De Vivo, I., Buring, J. E., Zhang, F., Edwards, T. L., Jones, S., Dorien, O., Peterse, D., Rexrode, K. M., Ridker, P. M., Schork, A. J., MacGregor, S., Martin, N. G., Becker, C. M., Adachi, S., Yoshihara, K. & 23 others, Enomoto, T., Takahashi, A., Kamatani, Y., Matsuda, K., Kubo, M., Thorleifsson, G., Geirsson, R. T., Thorsteinsdottir, U., Wallace, L. M., Werge, T. M., Thompson, W. K., Yang, J., Velez Edwards, DI. R., Nyegaard, M., Low, S. K., Zondervan, K. T., Missmer, S. A., D'Hooghe, T., Montgomery, G. W., Chasman, D. I., Stefansson, K., Tung, J. Y. & Nyholt, D. R., 24-05-2017, In : Nature communications. 8, 15539.

Research output: Contribution to journalArticle

77 Citations (Scopus)

Mitochondrial abnormality facilitates cyst formation in autosomal dominant polycystic kidney disease

Ishimoto, Y., Inagi, R., Yoshihara, D., Kugita, M., Nagao, S., Shimizu, A., Takeda, N., Wake, M., Honda, K., Zhou, J. & Nangaku, M., 01-12-2017, In : Molecular and Cellular Biology. 37, 24, e00337-17.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Molecular epidemiology of rotavirus gastroenteritis in Central Kenya before vaccine introduction, 2009–2014

Wandera, E. A., Mohammad, S., Komoto, S., Maeno, Y., Nyangao, J., Ide, T., Kathiiko, C., Odoyo, E., Tsuji, T., Taniguchi, K. & Ichinose, Y., 01-05-2017, In : Journal of Medical Virology. 89, 5, p. 809-817 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

New Pharmacogenomics Research Network: An Open Community Catalyzing Research and Translation in Precision Medicine

Relling, M. V., Krauss, R. M., Roden, D. M., Klein, T. E., Fowler, D. M., Terada, N., Lin, L., Riel-Mehan, M., Do, T. P., Kubo, M., Yee, S. W., Johnson, G. T. & Giacomini, K. M., 12-2017, In : Clinical Pharmacology and Therapeutics. 102, 6, p. 897-902 6 p.

Research output: Contribution to journalComment/debate

15 Citations (Scopus)

Ophthalmic formulation containing nilvadipine nanoparticles prevents retinal dysfunction in rats injected with streptozotocin

Deguchi, S., Otake, H., Nakazawa, Y., Hiramatsu, N., Yamamoto, N. & Nagai, N., 15-12-2017, In : International journal of molecular sciences. 18, 12, 2720.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Organotypic brain explant culture as a drug evaluation system for malignant brain tumors

Minami, N., Maeda, Y., Shibao, S., Arima, Y., Ohka, F., Kondo, Y., Maruyama, K., Kusuhara, M., Sasayama, T., Kohmura, E., Saya, H. & Sampetrean, O., 11-2017, In : Cancer Medicine. 6, 11, p. 2635-2645 11 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Overview of BioBank Japan follow-up data in 32 diseases

BioBank Japan Cooperative Hospital Group, 2017, In : Journal of epidemiology. 27, 3, p. S22-S28

Research output: Contribution to journalArticle

27 Citations (Scopus)

Overview of the BioBank Japan Project: Study design and profile

BioBank Japan Cooperative Hospital Group, 2017, In : Journal of epidemiology. 27, 3, p. S2-S8

Research output: Contribution to journalArticle

105 Citations (Scopus)

Pathogen lineage-based genome-wide association study identified CD53 as susceptible locus in tuberculosis

Omae, Y., Toyo-Oka, L., Yanai, H., Nedsuwan, S., Wattanapokayakit, S., Satproedprai, N., Smittipat, N., Palittapongarnpim, P., Sawanpanyalert, P., Inunchot, W., Pasomsub, E., Wichukchinda, N., Mushiroda, T., Kubo, M., Tokunaga, K. & Mahasirimongkol, S., 01-12-2017, In : Journal of Human Genetics. 62, 12, p. 1015-1022 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

PI3K-Akt pathway enhances the differentiation of interleukin-27-induced type 1 regulatory T cells

Nadya, N. A., Tezuka, H., Ohteki, T., Matsuda, S., Azuma, M. & Nagai, S., 11-2017, In : Immunology. 152, 3, p. 507-516 10 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis

Ishigaki, K., Kochi, Y., Suzuki, A., Tsuchida, Y., Tsuchiya, H., Sumitomo, S., Yamaguchi, K., Nagafuchi, Y., Nakachi, S., Kato, R., Sakurai, K., Shoda, H., Ikari, K., Taniguchi, A., Yamanaka, H., Miya, F., Tsunoda, T., Okada, Y., Momozawa, Y., Kamatani, Y. & 4 others, Yamada, R., Kubo, M., Fujio, K. & Yamamoto, K., 01-07-2017, In : Nature Genetics. 49, 7, p. 1120-1125 6 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Promethazine Hydrochloride Inhibits Ectopic Fat Cell Formation in Skeletal Muscle

Kasai, T., Nakatani, M., Ishiguro, N., Ohno, K., Yamamoto, N., Morita, M., Yamada, H., Tsuchida, K. & Uezumi, A., 12-2017, In : American Journal of Pathology. 187, 12, p. 2627-2634 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease

DiscovEHR Study Group & TAICHI Consortium, 23-06-2017, In : Circulation research. 121, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Reducing inflammatory cytokine production from renal collecting duct cells by inhibiting GATA2 ameliorates acute kidney injury

Yu, L., Moriguchi, T., Kaneko, H., Hayashi, M., Hasegawa, A., Nezu, M., Saya, H., Yamamoto, M. & Shimizu, R., 01-11-2017, In : Molecular and Cellular Biology. 37, 22, e00211-17.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Reverse genetics system demonstrates that rotavirus nonstructural protein NSP6 is not essential for viral replication in cell cultures

Komoto, S., Kanai, Y., Fukuda, S., Kugita, M., Kawagishi, T., Ito, N., Sugiyama, M., Matsuura, Y., Kobayashi, T. & Taniguchi, K., 01-11-2017, In : Journal of Virology. 91, 21, e00695-17.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Rheostatic CD44 isoform expression and its association with oxidative stress in human malignant mesothelioma

Chew, S. H., Okazaki, Y., Akatsuka, S., Wang, S., Jiang, L., Ohara, Y., Ito, F., Saya, H., Sekido, Y. & Toyokuni, S., 01-05-2017, In : Free Radical Biology and Medicine. 106, p. 91-99 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project

BioBank Japan Cooperative Hospital Group, 2017, In : Journal of epidemiology. 27, 3, p. S71-S76

Research output: Contribution to journalArticle

10 Citations (Scopus)

RNA Sequencing Analysis Reveals Interactions between Breast Cancer or Melanoma Cells and the Tissue Microenvironment during Brain Metastasis

Sato, R., Nakano, T., Hosonaga, M., Sampetrean, O., Harigai, R., Sasaki, T., Koya, I., Okano, H., Kudoh, J., Saya, H. & Arima, Y., 2017, In : BioMed Research International. 2017, 8032910.

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients: BioBank Japan

BioBank Japan Cooperative Hospital Group, 2017, In : Journal of epidemiology. 27, 3, p. S92-S97

Research output: Contribution to journalArticle

1 Citation (Scopus)

SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway

Dudenkov, T. M., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Ibrahim-zada, I., Batzler, A., Jenkins, G. D., Pietrzak, T. L., Carlson, E. E., Barman, P., Goetz, M. P., Northfelt, D. W., Moreno-Aspita, A., Williard, C. V., Kalari, K. R., Nakamura, Y., Wang, L. & Weinshilboum, R. M., 01-07-2017, In : Breast Cancer Research and Treatment. 164, 1, p. 189-199 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Stat3 as a potential therapeutic target for rheumatoid arthritis

Oike, T., Sato, Y., Kobayashi, T., Miyamoto, K., Nakamura, S., Kaneko, Y., Kobayashi, S., Harato, K., Saya, H., Matsumoto, M., Nakamura, M., Niki, Y. & Miyamoto, T., 01-12-2017, In : Scientific reports. 7, 1, 10965.

Research output: Contribution to journalArticle

Open Access
20 Citations (Scopus)

Statin use and all-cause and cancer mortality: BioBank Japan cohort

BioBank Japan Cooperative Hospital Group, 2017, In : Journal of epidemiology. 27, 3, p. S84-S91

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12 Citations (Scopus)

Strain-based HLA association analysis identified HLA-DRB1*09:01 associated with modern strain tuberculosis

Toyo-oka, L., Mahasirimongkol, S., Yanai, H., Mushiroda, T., Wattanapokayakit, S., Wichukchinda, N., Yamada, N., Smittipat, N., Juthayothin, T., Palittapongarnpim, P., Nedsuwan, S., Kantipong, P., Takahashi, A., Kubo, M., Sawanpanyalert, P. & Tokunaga, K., 09-2017, In : HLA. 90, 3, p. 149-156 8 p.

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10 Citations (Scopus)

Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort

BioBank Japan Cooperative Hospital Group, 01-03-2017, In : Journal of epidemiology. 27, 3, p. S98-S106

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9 Citations (Scopus)

TALEN-mediated shift of mitochondrial DNA heteroplasmy in MELAS-iPSCs with m.13513G>A mutation

Yahata, N., Matsumoto, Y., Omi, M., Yamamoto, N. & Hata, R., 01-12-2017, In : Scientific reports. 7, 1, 15557.

Research output: Contribution to journalArticle

15 Citations (Scopus)

T cells bearing anti-CD19 and/or anti-CD38 chimeric antigen receptors effectively abrogate primary double-hit lymphoma cells

Mihara, K., Yoshida, T., Takei, Y., Sasaki, N., Takihara, Y., Kuroda, J. & Ichinohe, T., 08-06-2017, In : Journal of Hematology and Oncology. 10, 1, 116.

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Open Access
10 Citations (Scopus)

TCL1A Single-Nucleotide Polymorphisms and Estrogen-Mediated Toll-Like Receptor-MyD88–Dependent Nuclear Factor-kB Activation: Single-Nucleotide Polymorphism– and Selective Estrogen Receptor Modulator–Dependent Modification of Inflammation and Immune Response

Ho, M. F., Ingle, J. N., Bongartz, T., Kalari, K. R., Goss, P. E., Shepherd, L. E., Mushiroda, T., Kubo, M., Wang, L. & Weinshilboum, R. M., 08-2017, In : Molecular Pharmacology. 92, 2, p. 175-184 10 p.

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7 Citations (Scopus)

Telomere length as a potential biomarker of coronary artery disease

Bhattacharyya, J., Mihara, K., Bhattacharjee, D. & Mukherjee, M., 06-2017, In : Indian Journal of Medical Research. 145, June, p. 730-737 8 p.

Research output: Contribution to journalReview article

Open Access
14 Citations (Scopus)

The gene-treatment interaction of paraoxonase-1 gene polymorphism and statin therapy on insulin secretion in Japanese patients with type 2 diabetes: Fukuoka diabetes registry

Sumi, A., Nakamura, U., Iwase, M., Fujii, H., Ohkuma, T., Ide, H., Jodai-Kitamura, T., Komorita, Y., Yoshinari, M., Hirakawa, Y., Hirano, A., Kubo, M. & Kitazono, T., 12-12-2017, In : BMC Medical Genetics. 18, 1, 146.

Research output: Contribution to journalArticle

5 Citations (Scopus)