Research Promotion and Support Headquarters

Research Output

2016

Erratum: Arsenic trioxide sensitizes glioblastoma to a myc inhibitor (PLoS ONE 10:6 (e0128288) DOI 10.1371/journal.pone.0128288)

Yoshimura, Y., Shiino, A., Muraki, K., Fukami, T., Yamada, S., Satow, T., Fukuda, M., Saiki, M., Hojo, M., Miyamoto, S., Onishi, N., Saya, H., Inubushi, T., Nozaki, K. & Tanigaki, K., 02-2016, In : PloS one. 11, 2, e0149826.

Research output: Contribution to journalComment/debate

Open Access

Establishment of a new immortalized human corneal epithelial cell line (iHCE-NY1) for use in evaluating eye irritancy by in vitro test methods

Yamamoto, N., Kato, Y., Sato, A., Hiramatsu, N., Yamashita, H., Ohkuma, M., Miyachi, E. I., Horiguchi, M., Hirano, K. & Kojima, H., 01-08-2016, In : In Vitro Cellular and Developmental Biology - Animal. 52, 7, p. 742-748 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Estrogen, SNP-dependent chemokine expression and selective estrogen receptor modulator regulation

Ho, M. F., Bongartz, T., Liu, M., Kalari, K. R., Goss, P. E., Shepherd, L. E., Goetz, M. P., Kubo, M., Ingle, J. N., Wang, L. & Weinshilboum, R. M., 03-2016, In : Molecular Endocrinology. 30, 3, p. 382-398 17 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Full Genome Characterization of Novel DS-1-Like G8P[8] Rotavirus Strains that Have Emerged in Thailand: Reassortment of Bovine and Human Rotavirus Gene Segments in Emerging DS-1-Like Intergenogroup Reassortant Strains

Tacharoenmuang, R., Komoto, S., Guntapong, R., Ide, T., Sinchai, P., Upachai, S., Yoshikawa, T., Tharmaphornpilas, P., Sangkitporn, S. & Taniguchi, K., 11-2016, In : PloS one. 11, 11, 165826.

Research output: Contribution to journalArticle

17 Citations (Scopus)

GANP protein encoded on human chromosome 21/mouse chromosome 10 is associated with resistance to mammary tumor development

Kuwahara, K., Yamamoto-Ibusuki, M., Zhang, Z., Phimsen, S., Gondo, N., Yamashita, H., Takeo, T., Nakagata, N., Yamashita, D., Fukushima, Y., Yamamoto, Y., Iwata, H., Saya, H., Kondo, E., Matsuo, K., Takeya, M., Iwase, H. & Sakaguchi, N., 01-04-2016, In : Cancer science. 107, 4, p. 469-477 9 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Generation of a novel transgenic rat model for tracing extracellular vesicles in body fluids

Yoshimura, A., Kawamata, M., Yoshioka, Y., Katsuda, T., Kikuchi, H., Nagai, Y., Adachi, N., Numakawa, T., Kunugi, H., Ochiya, T. & Tamai, Y., 19-08-2016, In : Scientific reports. 6, 31172.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Generation of heterozygous fibrillin-1 mutant cloned pigs from genome-edited foetal fibroblasts

Umeyama, K., Watanabe, K., Watanabe, M., Horiuchi, K., Nakano, K., Kitashiro, M., Matsunari, H., Kimura, T., Arima, Y., Sampetrean, O., Nagaya, M., Saito, M., Saya, H., Kosaki, K., Nagashima, H. & Matsumoto, M., 14-04-2016, In : Scientific reports. 6, 24413.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Pattaro, C., Teumer, A., Gorski, M., Chu, A. Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M. H., Pers, T. H., Johnson, A. D., Ko, Y. A., Fuchsberger, C., Tayo, B. & 678 others, Nalls, M., Feitosa, M. F., Isaacs, A., Dehghan, A., D'Adamo, P., Adeyemo, A., Dieffenbach, A. K., Zonderman, A. B., Nolte, I. M., Van Der Most, P. J., Wright, A. F., Shuldiner, A. R., Morrison, A. C., Hofman, A., Smith, A. V., Dreisbach, A. W., Franke, A., Uitterlinden, A. G., Metspalu, A., Tonjes, A., Lupo, A., Robino, A., Johansson, Å., Demirkan, A., Kollerits, B., Freedman, B. I., Ponte, B., Oostra, B. A., Paulweber, B., Krämer, B. K., Mitchell, B. D., Buckley, B. M., Peralta, C. A., Hayward, C., Helmer, C., Rotimi, C. N., Shaffer, C. M., Müller, C., Sala, C., Van Duijn, C. M., Saint-Pierre, A., Ackermann, D., Shriner, D., Ruggiero, D., Toniolo, D., Lu, Y., Cusi, D., Czamara, D., Ellinghaus, D., Siscovick, D. S., Ruderfer, D., Gieger, C., Grallert, H., Rochtchina, E., Atkinson, E. J., Holliday, E. G., Boerwinkle, E., Salvi, E., Bottinger, E. P., Murgia, F., Rivadeneira, F., Ernst, F., Kronenberg, F., Hu, F. B., Navis, G. J., Curhan, G. C., Ehret, G. B., Homuth, G., Coassin, S., Thun, G. A., Pistis, G., Gambaro, G., Malerba, G., Montgomery, G. W., Eiriksdottir, G., Jacobs, G., Li, G., Wichmann, H. E., Campbell, H., Schmidt, H., Wallaschofski, H., Völzke, H., Brenner, H., Kroemer, H. K., Kramer, H., Lin, H., Leach, I. M., Ford, I., Guessous, I., Rudan, I., Prokopenko, I., Borecki, I., Heid, I. M., Kolcic, I., Persico, I., Jukema, J. W., Wilson, J. F., Felix, J. F., Divers, J., Lambert, J. C., Stafford, J. M., Gaspoz, J. M., Smith, J. A., Faul, J. D., Wang, J. J., Ding, J., Hirschhorn, J. N., Attia, J., Whitfield, J. B., Chalmers, J., Viikari, J., Coresh, J., Denny, J. C., Karjalainen, J., Fernandes, J. K., Endlich, K., Butterbach, K., Keene, K. L., Lohman, K., Portas, L., Launer, L. J., Lyytikäinen, L. P., Yengo, L., Franke, L., Ferrucci, L., Rose, L. M., Kedenko, L., Rao, M., Struchalin, M., Kleber, M. E., Cavalieri, M., Haun, M., Cornelis, M. C., Ciullo, M., Pirastu, M., De Andrade, M., McEvoy, M. A., Woodward, M., Adam, M., Cocca, M., Nauck, M., Imboden, M., Waldenberger, M., Pruijm, M., Metzger, M., Stumvoll, M., Evans, M. K., Sale, M. M., Kähönen, M., Boban, M., Bochud, M., Rheinberger, M., Verweij, N., Bouatia-Naji, N., Martin, N. G., Hastie, N., Probst-Hensch, N., Soranzo, N., Devuyst, O., Raitakari, O., Gottesman, O., Franco, O. H., Polasek, O., Gasparini, P., Munroe, P. B., Ridker, P. M., Mitchell, P., Muntner, P., Meisinger, C., Smit, J. H., Abecasis, G. R., Adair, L. S., Alexander, M., Altshuler, D., Amin, N., Arking, D. E., Arora, P., Aulchenko, Y., Bakker, S. J. L., Bandinelli, S., Barroso, I., Beckmann, J. S., Beilby, J. P., Bergman, R. N., Bergmann, S., Bis, J. C., Boehnke, M., Bonnycastle, L. L., Bornstein, S. R., Bots, M. L., Bragg-Gresham, J. L., Brand, S. M., Brand, E., Braund, P. S., Brown, M. J., Burton, P. R., Casas, J. P., Caulfield, M. J., Chakravarti, A., Chambers, J. C., Chandak, G. R., Chang, Y. P. C., Charchar, F. J., Chaturvedi, N., Cho, Y. S., Clarke, R., Collins, F. S., Collins, R., Connell, J. M., Cooper, J. A., Cooper, M. N., Cooper, R. S., Corsi, A. M., Dörr, M., Dahgam, S., Danesh, J., Smith, G. D., Day, I. N. M., Deloukas, P., Denniff, M., Dominiczak, A. F., Dong, Y., Doumatey, A., Elliott, P., Elosua, R., Erdmann, J., Eyheramendy, S., Farrall, M., Fava, C., Forrester, T., Fowkes, F. G. R., Fox, E. R., Frayling, T. M., Galan, P., Ganesh, S. K., Garcia, M., Gaunt, T. R., Glazer, N. L., Go, M. J., Goel, A., Grässler, J., Grobbee, D. E., Groop, L., Guarrera, S., Guo, X., Hadley, D., Hamsten, A., Han, B. G., Hardy, R., Hartikainen, A. L., Heath, S., Heckbert, S. R., Hedblad, B., Hercberg, S., Hernandez, D., Hicks, A. A., Hilton, G., Hingorani, A. D., Hoffman Bolton, J. A., Hopewell, J. C., Howard, P., Humphries, S. E., Hunt, S. C., Hveem, K., Ikram, M. A., Islam, M., Iwai, N., Jarvelin, M. R., Jackson, A. U., Jafar, T. H., Janipalli, C. S., Johnson, T., Kathiresan, S., Khaw, K. T., Kim, H. L., Kinra, S., Kita, Y., Kivimaki, M., Kooner, J. S., Kumar, M. J. K., Kuh, D., Kulkarni, S. R., Kumari, M., Kuusisto, J., Kuznetsova, T., Laakso, M., Laan, M., Laitinen, J., Lakatta, E. G., Langefeld, C. D., Larson, M. G., Lathrop, M., Lawlor, D. A., Lawrence, R. W., Lee, J. Y., Lee, N. R., Levy, D., Li, Y., Longstreth, W. T., Luan, J., Lucas, G., Ludwig, B., Mangino, M., Mani, K. R., Marmot, M. G., Mattace-Raso, F. U. S., Matullo, G., McArdle, W. L., McKenzie, C. A., Meitinger, T., Melander, O., Meneton, P., Meschia, J. F., Miki, T., Milaneschi, Y., Mohlke, K. L., Mooser, V., Morken, M. A., Morris, R. W., Mosley, T. H., Najjar, S., Narisu, N., Newton-Cheh, C., Nguyen, K. D. H., Nilsson, P., Nyberg, F., O'Donnell, C. J., Ogihara, T., Ohkubo, T., Okamura, T., Ong, R. T. H., Ongen, H., Onland-Moret, N. C., O'Reilly, P. F., Org, E., Orru, M., Palmas, W., Palmen, J., Palmer, L. J., Palmer, N. D., Parker, A. N., Peden, J. F., Peltonen, L., Perola, M., Pihur, V., Platou, C. G. P., Plump, A., Prabhakaran, D., Psaty, B. M., Raffel, L. J., Rao, D. C., Rasheed, A., Ricceri, F., Rice, K. M., Rosengren, A., Rotter, J. I., Rudock, M. E., Sõber, S., Salako, T., Saleheen, D., Salomaa, V., Samani, N. J., Schwartz, S. M., Schwarz, P. E. H., Scott, L. J., Scott, J., Scuteri, A., Sehmi, J. S., Seielstad, M., Seshadri, S., Sharma, P., Shaw-Hawkins, S., Shi, G., Shrine, N. R. G., Sijbrands, E. J. G., Sim, X., Singleton, A., Sjögren, M., Smith, N. L., Artigas, M. S., Spector, T. D., Staessen, J. A., Stancakova, A., Steinle, N. I., Strachan, D. P., Stringham, H. M., Sun, Y. V., Swift, A. J., Tabara, Y., Tai, E. S., Talmud, P. J., Taylor, A., Terzic, J., Thelle, D. S., Tobin, M. D., Tomaszewski, M., Tripathy, V., Tuomilehto, J., Tzoulaki, I., Uda, M., Ueshima, H., Uiterwaal, C. S. P. M., Umemura, S., Van Der Harst, P., Van Der Schouw, Y. T., Van Gilst, W. H., Vartiainen, E., Vasan, R. S., Veldre, G., Verwoert, G. C., Viigimaa, M., Vinay, D. G., Vineis, P., Voight, B. F., Vollenweider, P., Wagenknecht, L. E., Wain, L. V., Wang, X., Wang, T. J., Wareham, N. J., Watkins, H., Weder, A. B., Whincup, P. H., Wiggins, K. L., Witteman, J. C. M., Wong, A., Wu, Y., Yajnik, C. S., Yao, J., Young, J. H., Zelenika, D., Zhai, G., Zhang, W., Zhang, F., Zhao, J. H., Zhu, H., Zhu, X., Zitting, P., Zukowska-Szczechowska, E., Okada, Y., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Teo, Y. Y., Kim, Y. J., Kang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J. C., Mei, H., Hixson, J. E., Chen, S., Katsuya, T., Isono, M., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y. T., Tanaka, T., Reilly, M. P., Schunkert, H., Assimes, T. L., Hall, A., Hengstenberg, C., König, I. R., Laaksonen, R., McPherson, R., Thompson, J. R., Thorsteinsdottir, U., Ziegler, A., Absher, D., Chen, L., Cupples, L. A., Halperin, E., Li, M., Musunuru, K., Preuss, M., Schillert, A., Thorleifsson, G., Wells, G. A., Holm, H., Roberts, R., Stewart, A. F. R., Fortmann, S., Go, A., Hlatky, M., Iribarren, C., Knowles, J., Myers, R., Quertermous, T., Sidney, S., Risch, N., Tang, H., Blankenberg, S., Schnabel, R., Sinning, C., Lackner, K. J., Tiret, L., Nicaud, V., Cambien, F., Bickel, C., Rupprecht, H. J., Perret, C., Proust, C., Münzel, T. F., Barbalic, M., Chen, I. Y. D., Demissie-Banjaw, S., Folsom, A., Lumley, T., Marciante, K., Taylor, K. D., Volcik, K., Gretarsdottir, S., Gulcher, J. R., Kong, A., Stefansson, K., Thorgeirsson, G., Andersen, K., Fischer, M., Grosshennig, A., Linsel-Nitschke, P., Stark, K., Schreiber, S., Aherrahrou, Z., Bruse, P., Doering, A., Klopp, N., Diemert, P., Loley, C., Medack, A., Nahrstedt, J., Peters, A., Wagner, A. K., Willenborg, C., Böhm, B. O., Dobnig, H., Grammer, T. B., Hoffmann, M. M., Meinitzer, A., Winkelmann, B. R., Pilz, S., Renner, W., Scharnagl, H., Stojakovic, T., Tomaschitz, A., Winkler, K., Guiducci, C., Burtt, N., Gabriel, S. B., Dandona, S., Jarinova, O., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Devaney, J., Burnett, M. S., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Knouff, C. W., Waterworth, D. M., Walker, M. C., Epstein, S. E., Rader, D. J., Nelson, C. P., Wright, B. J., Balmforth, A. J., Ball, S. G., Loehr, L. R., Rosamond, W. D., Benjamin, E., Haritunians, T., Couper, D., Murabito, J., Wang, Y. A., Stricker, B. H., Chang, P. P., Willerson, J. T., Felix, S. B., Watzinger, N., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R. J., Greiser, K. H., Deckers, J. W., Stritzke, J., Ingelsson, E., Kullo, I., Haerting, J., Reffelmann, T., Redfield, M. M., Werdan, K., Mitchell, G. F., Arnett, D. K., Gottdiener, J. S., Blettner, M., Friedrich, N., Kovacs, P., Wild, P. S., Froguel, P., Rettig, R., Mägi, R., Biffar, R., Schmidt, R., Middelberg, R. P. S., Carroll, R. J., Penninx, B. W., Scott, R. J., Katz, R., Sedaghat, S., Wild, S. H., Kardia, S. L. R., Ulivi, S., Hwang, S. J., Enroth, S., Kloiber, S., Trompet, S., Stengel, B., Hancock, S. J., Turner, S. T., Rosas, S. E., Stracke, S., Harris, T. B., Zeller, T., Zemunik, T., Lehtimäki, T., Illig, T., Aspelund, T., Nikopensius, T., Esko, T., Tanaka, T., Gyllensten, U., Völker, U., Emilsson, V., Vitart, V., Aalto, V., Gudnason, V., Chouraki, V., Chen, W. M., Igl, W., März, W., Koenig, W., Lieb, W., Loos, R. J. F., Liu, Y., Snieder, H., Pramstaller, P. P., Parsa, A., O'Connell, J. R., Susztak, K., Hamet, P., Tremblay, J., De Boer, I. H., Böger, C. A., Goessling, W., Chasman, D. I., Köttgen, A., Kao, W. H. L. & Fox, C. S., 21-01-2016, In : Nature communications. 7, 10023.

Research output: Contribution to journalArticle

200 Citations (Scopus)

Genetic characteristics of inflammatory bowel disease in a Japanese population

Fuyuno, Y., Yamazaki, K., Takahashi, A., Esaki, M., Kawaguchi, T., Takazoe, M., Matsumoto, T., Matsui, T., Tanaka, H., Motoya, S., Suzuki, Y., Kiyohara, Y., Kitazono, T. & Kubo, M., 01-07-2016, In : Journal of Gastroenterology. 51, 7, p. 672-681 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Genetic polymorphisms in the long noncoding RNA MIR2052HG offer a pharmacogenomic basis for the response of breast cancer patients to aromatase inhibitor therapy

Ingle, J. N., Xie, F., Ellis, M. J., Goss, P. E., Shepherd, L. E., Chapman, J. A. W., Chen, B. E., Kubo, M., Furukawa, Y., Momozawa, Y., Stearns, V., Pritchard, K. I., Barman, P., Carlson, E. E., Goetz, M. P., Weinshilboum, R. M., Kalari, K. R. & Wang, L., 01-12-2016, In : Cancer Research. 76, 23, p. 7012-7023 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Genetic risk score based on the prevalence of vertebral fracture in Japanese women with osteoporosis

Zhou, H., Mori, S., Ishizaki, T., Takahashi, A., Matsuda, K., Koretsune, Y., Minami, S., Higashiyama, M., Imai, S., Yoshimori, K., Doita, M., Yamada, A., Nagayama, S., Kaneko, K., Asai, S., Shiono, M., Kubo, M. & Ito, H., 01-12-2016, In : Bone Reports. 5, p. 168-172 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Genetic Variation in the SLC8A1 Calcium Signaling Pathway Is Associated with Susceptibility to Kawasaki Disease and Coronary Artery Abnormalities

Shimizu, C., Eleftherohorinou, H., Wright, V. J., Kim, J., Alphonse, M. P., Perry, J. C., Cimaz, R., Burgner, D., Dahdah, N., Hoang, L. T., Khor, C. C., Salgado, A., Tremoulet, A. H., Davila, S., Kuijpers, T. W., Hibberd, M. L., Johnson, T. A., Takahashi, A., Tsunoda, T., Kubo, M. & 6 others, Tanaka, T., Onouchi, Y., Yeung, R. S. M., Coin, L. J. M., Levin, M. & Burns, J. C., 01-12-2016, In : Circulation: Cardiovascular Genetics. 9, 6, p. 559-568 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity

Petros, Z., Lee, M. T. M., Takahashi, A., Zhang, Y., Yimer, G., Habtewold, A., Amogne, W., Aderaye, G., Schuppe-Koistinen, I., Mushiroda, T., Makonnen, E., Kubo, M. & Aklillu, E., 26-09-2016, In : BMC Genomics. 17, 1, 755.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Genomewide Association Studies in Pharmacogenomics: Meeting Report of the NIH Pharmacogenomics Research Network-RIKEN (PGRN-RIKEN) Collaboration

Yee, S. W., Momozawa, Y., Kamatani, Y., Tyndale, R. F., Weinshilboum, R. M., Ratain, M. J., Giacomini, K. M. & Kubo, M., 01-11-2016, In : Clinical Pharmacology and Therapeutics. p. 423-426 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

Imamura, M., Takahashi, A., Yamauchi, T., Hara, K., Yasuda, K., Grarup, N., Zhao, W., Wang, X., Huerta-Chagoya, A., Hu, C., Moon, S., Long, J., Kwak, S. H., Rasheed, A., Saxena, R., Ma, R. C. W., Okada, Y., Iwata, M., Hosoe, J., Shojima, N. & 43 others, Iwasaki, M., Fujita, H., Suzuki, K., Danesh, J., Jørgensen, T., Jørgensen, M. E., Witte, D. R., Brandslund, I., Christensen, C., Hansen, T., Mercader, J. M., Flannick, J., Moreno-Macías, H., Burtt, N. P., Zhang, R., Kim, Y. J., Zheng, W., Singh, J. R., Tam, C. H. T., Hirose, H., Maegawa, H., Ito, C., Kaku, K., Watada, H., Tanaka, Y., Tobe, K., Kawamori, R., Kubo, M., Cho, Y. S., Chan, J. C. N., Sanghera, D., Frossard, P., Park, K. S., Shu, X. O., Kim, B. J., Florez, J. C., Tusié-Luna, T., Jia, W., Tai, E. S., Pedersen, O., Saleheen, D., Maeda, S. & Kadowaki, T., 28-01-2016, In : Nature communications. 7, 10531.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Genome-wide association studies of drug response and toxicity: An opportunity for genome medicine

Giacomini, K. M., Yee, S. W., Mushiroda, T., Weinshilboum, R. M., Ratain, M. J. & Kubo, M., 29-12-2016, In : Nature Reviews Drug Discovery. 16, 1, p. 1 1 p.

Research output: Contribution to journalLetter

36 Citations (Scopus)

Genome-wide association study in East Asians identifies two novel breast cancer susceptibility loci

Han, M. R., Long, J., Choi, J. Y., Low, S. K., Kweon, S. S., Zheng, Y., Cai, Q., Shi, J., Guo, X., Matsuo, K., Iwasaki, M., Shen, C. Y., Kim, M. K., Wen, W., Li, B., Takahashi, A., Shin, M. H., Xiang, Y. B., Ito, H., Kasuga, Y. & 11 others, Noh, D. Y., Matsuda, K., Park, M. H., Gao, Y. T., Iwata, H., Tsugane, S., Park, S. K., Kubo, M., Shu, X. O., Kang, D. & Zheng, W., 2016, In : Human molecular genetics. 25, 15, p. 3361-3371 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Genome-wide association study of clinically defined Gout identifies multiple risk loci and its association with clinical subtypes

Matsuo, H., Yamamoto, K., Nakaoka, H., Nakayama, A., Sakiyama, M., Chiba, T., Takahashi, A., Nakamura, T., Nakashima, H., Takada, Y., Danjoh, I., Shimizu, S., Abe, J., Kawamura, Y., Terashige, S., Ogata, H., Tatsukawa, S., Yin, G., Okada, R., Morita, E. & 20 others, Naito, M., Tokumasu, A., Onoue, H., Iwaya, K., Ito, T., Takada, T., Inoue, K., Kato, Y., Nakamura, Y., Sakurai, Y., Suzuki, H., Kanai, Y., Hosoya, T., Hamajima, N., Inoue, I., Kubo, M., Ichida, K., Ooyama, H., Shimizu, T. & Shinomiya, N., 04-2016, In : Annals of the Rheumatic Diseases. 75, 4, p. 652-659 8 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Genome-wide association study of leukotriene modifier response in asthma

Dahlin, A., Litonjua, A., Irvin, C. G., Peters, S. P., Lima, J. J., Kubo, M., Tamari, M. & Tantisira, K. G., 01-04-2016, In : Pharmacogenomics Journal. 16, 2, p. 151-157 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Genome-wide environment interaction between depressive state and stressful life events

Ikeda, M., Shimasaki, A., Takahashi, A., Kondo, K., Saito, T., Kawase, K., Esaki, K., Otsuka, Y., Mano, K., Kubo, M. & Iwata, N., 01-2016, In : Journal of Clinical Psychiatry. 77, 1, p. e29-e30

Research output: Contribution to journalLetter

14 Citations (Scopus)

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

Sun, C., Molineros, J. E., Looger, L. L., Zhou, X. J., Kim, K., Okada, Y., Ma, J., Qi, Y. Y., Kim-Howard, X., Motghare, P., Bhattarai, K., Adler, A., Bang, S. Y., Lee, H. S., Kim, T. H., Kang, Y. M., Suh, C. H., Chung, W. T., Park, Y. B., Choe, J. Y. & 18 others, Shim, S. C., Kochi, Y., Suzuki, A., Kubo, M., Sumida, T., Yamamoto, K., Lee, S. S., Kim, Y. J., Han, B. G., Dozmorov, M., Kaufman, K. M., Wren, J. D., Harley, J. B., Shen, N., Chua, K. H., Zhang, H., Bae, S. C. & Nath, S. K., 01-03-2016, In : Nature Genetics. 48, 3, p. 323-330 8 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)

High prevalence of G12 human rotaviruses in children with gastroenteritis in Myanmar

Ide, T., Higo-Moriguchi, K., Komoto, S., Htun, K. W., Myint, Y. Y., Myat, T. W., Thant, K. Z., Thu, H. M., Win, M. M., Oo, H. N., Htut, T., Rahman, S., Van Nguyen, S., Umeda, K., Oguma, K., Tsuji, T. & Taniguchi, K., 2016, In : Japanese journal of infectious diseases. 69, 4, p. 326-327 2 p.

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2 Citations (Scopus)

High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery

Kizuka, Y., Funayama, S., Shogomori, H., Nakano, M., Nakajima, K., Oka, R., Kitazume, S., Yamaguchi, Y., Sano, M., Korekane, H., Hsu, T. L., Lee, H. Y., Wong, C. H. & Taniguchi, N., 21-07-2016, In : Cell Chemical Biology. 23, 7, p. 782-792 11 p.

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15 Citations (Scopus)

Hippocampus-dependent spatial memory impairment due to molar tooth loss is ameliorated by an enriched environment

Kondo, H., Kurahashi, M., Mori, D., Iinuma, M., Tamura, Y., Mizutani, K., Shimpo, K., Sonoda, S., Azuma, K. & Kubo, K. Y., 01-2016, In : Archives of Oral Biology. 61, p. 1-7 7 p., 3473.

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15 Citations (Scopus)

Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans

Lee, S. A., Mefford, J. A., Huang, Y., Witte, J. S., Martin, J. N., Haas, D. W., McLaren, P. J., Mushiroda, T., Kubo, M., Byakwaga, H., Hunt, P. W. & Kroetz, D. L., 17-07-2016, In : AIDS. 30, 11, p. 1807-1815 9 p.

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9 Citations (Scopus)

Hyaluronan production regulates metabolic and cancer stem-like properties of breast cancer cells via hexosamine biosynthetic pathway-coupled HIF-1 signaling

Chanmee, T., Ontong, P., Izumikawa, T., Higashide, M., Mochizuki, N., Chokchaitaweesuk, C., Khansai, M., Nakajima, K., Kakizaki, I., Kongtawelert, P., Taniguchi, N. & Itano, N., 11-11-2016, In : Journal of Biological Chemistry. 291, 46, p. 24105-24120 16 p.

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29 Citations (Scopus)

Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk

Zeng, C., Matsuda, K., Jia, W. H., Chang, J., Kweon, S. S., Xiang, Y. B., Shin, A., Jee, S. H., Kim, D. H., Zhang, B., Cai, Q., Guo, X., Long, J., Wang, N., Courtney, R., Pan, Z. Z., Wu, C., Takahashi, A., Shin, M. H., Matsuo, K. & 87 others, Matsuda, F., Gao, Y. T., Oh, J. H., Kim, S., Jung, K. J., Ahn, Y. O., Ren, Z., Li, H. L., Wu, J., Shi, J., Wen, W., Yang, G., Li, B., Ji, B. T., Gruber, S. B., Schumacher, F. R., Stenzel, S. L., Casey, G., Hopper, J. L., Jenkins, M. A., Kim, H. R., Jeong, J. Y., Park, J. W., Tajima, K., Cho, S. H., Kubo, M., Shu, X. O., Lin, D., Zeng, Y. X., Zheng, W., Brenner, H., Schoen, R. E., Küry, S., Baron, J. A., Berndt, S. I., Bezieau, S., Caan, B. J., Carlson, C. S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Conti, D. V., Curtis, K., Duggan, D., Fuchs, C. S., Gallinger, S., Giovannucci, E. L., Haile, R. W., Harrison, T. A., Hayes, R. B., Hoffmeister, M., Hsu, L., Hudson, T. J., Hunter, D. J., Hutter, C. M., Jackson, R. D., Jiao, S., Le Marchand, L., Lemire, M., Lindor, N. M., Ma, J., Newcomb, P. A., Peters, U., Potter, J. D., Qu, C., Seminara, D., Slattery, M. L., Thibodeau, S. N., White, E., Zanke, B. W., Blalock, K., Campbell, P. T., Edlund, C. K., Figueiredo, J., Gauderman, W. J., Gong, J., Green, R. C., Harju, J. F., Jacobs, E. J., Li, L., Lin, Y., Manion, F. J., Moreno, V., Mukherjee, B., Raskin, L., Severi, G. & Thomas, D. C., 01-06-2016, In : Gastroenterology. 150, 7, p. 1633-1645 13 p.

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48 Citations (Scopus)

Induction of HLA-B*40:02-restricted T cells possessing cytotoxic and suppressive functions against haematopoietic progenitor cells from a patient with severe aplastic anaemia

Inaguma, Y., Akatsuka, Y., Hosokawa, K., Maruyama, H., Okamoto, A., Katagiri, T., Shiraishi, K., Murayama, Y., Tsuzuki-Iba, S., Mizutani, Y., Nishii, C., Yamamoto, N., Demachi-Okamura, A., Kuzushima, K., Ogawa, S., Emi, N. & Nakao, S., 01-01-2016, In : British Journal of Haematology. 172, 1, p. 131-134 4 p.

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10 Citations (Scopus)

Influence of cigarette smoking and inflammatory gene polymorphisms on glycated hemoglobin in the Japanese general population

for the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group, 01-06-2016, In : Preventive Medicine Reports. 3, p. 288-295 8 p.

Research output: Contribution to journalArticle

Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort

The Malaysian NPC Study Group, 15-10-2016, In : International Journal of Cancer. 139, 8, p. 1731-1739 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

In vitro antiproliferative activity of 2,3-dihydroxy-9,10-anthraquinone induced apoptosis against COLO320 cells through cytochrome c release caspase mediated pathway with PI3K/AKT and COX-2 inhibition

Balachandran, C., Emi, N., Arun, Y., Yamamoto, N., Duraipandiyan, V., Inaguma, Y., Okamoto, A., Ignacimuthu, S., Al-Dhabi, N. A. & Perumal, P. T., 05-04-2016, In : Chemico-Biological Interactions. 249, p. 23-35 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Isoflurane induces transient impairment of retention of spatial working memory in rats

Tanino, M., Kobayashi, M., Sasaki, T., Takata, K., Takeda, Y., Mizobuchi, S., Morita, K., Nagai, T. & Morimatsu, H., 2016, In : Acta Medica Okayama. 70, 6, p. 455-460 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Isolation of all CD44 transcripts in human epidermis and regulation of their expression by various agents

Teye, K., Numata, S., Ishii, N., Krol, R. P., Tsuchisaka, A., Hamada, T., Koga, H., Karashima, T., Ohata, C., Tsuruta, D., Saya, H., Haftek, M. & Hashimoto, T., 08-2016, In : PloS one. 11, 8, e0160952.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Kinetic and molecular orbital analyses of dicarboxylic acylcarnitine methylesterification show that derivatization may affect the screening of newborns by tandem mass spectrometry

Maeda, Y., Nakajima, Y., Gotoh, K., Hotta, Y., Kataoka, T., Sugiyama, N., Shirai, N., Ito, T. & Kimura, K., 01-01-2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 1, p. 121-125 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development

Lee, D. H., Park, J. O., Kim, T. S., Kim, S. K., Kim, T. H., Kim, M. C., Park, G. S., Kim, J. H., Kuninaka, S., Olson, E. N., Saya, H., Kim, S. Y., Lee, H. & Lim, D. S., 30-06-2016, In : Nature communications. 7, 11961.

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Open Access
79 Citations (Scopus)

Light-controlled relaxation of the rat penile corpus cavernosum using NOBL-1, a novel nitric oxide releaser

Hotta, Y., Ieda, N., Fukamoto, A., Kataoka, T., Kawade, Y., Maeda, Y., Nakagawa, H. & Kimura, K., 05-2016, In : Investigative and Clinical Urology. 57, 3, p. 215-220 6 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Low-frequency coding variants in CETP and CFB are associated with susceptibility of exudative age-related macular degeneration in the Japanese population

Momozawa, Y., Akiyama, M., Kamatani, Y., Arakawa, S., Yasuda, M., Yoshida, S., Oshima, Y., Mori, R., Tanaka, K., Mori, K., Inoue, S., Terasaki, H., Yasuma, T., Honda, S., Miki, A., Inoue, M., Fujisawa, K., Takahashi, K., Yasukawa, T., Yanagi, Y. & 5 others, Kadonosono, K., Sonoda, K. H., Ishibashi, T., Takahashi, A. & Kubo, M., 15-11-2016, In : Human molecular genetics. 25, 22, p. 5027-5034 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

Wang, Z., Seow, W. J., Shiraishi, K., Hsiung, C. A., Matsuo, K., Liu, J., Chen, K., Yamji, T., Yang, Y., Chang, I. S., Wu, C., Hong, Y. C., Burdett, L., Wyatt, K., Chung, C. C., Li, S. A., Yeager, M., Hutchinson, A., Hu, W., Caporaso, N. & 130 others, Landi, M. T., Chatterjee, N., Song, M., Fraumeni, J. F., Kohno, T., Yokota, J., Kunitoh, H., Ashikawa, K., Momozawa, Y., Daigo, Y., Mitsudomi, T., Yatabe, Y., Hida, T., Hu, Z., Dai, J., Ma, H., Jin, G., Song, B., Wang, Z., Cheng, S., Yin, Z., Li, X., Ren, Y., Guan, P., Chang, J., Tan, W., Chen, C. J., Chang, G. C., Tsai, Y. H., Su, W. C., Chen, K. Y., Huang, M. S., Chen, Y. M., Zheng, H., Li, H., Cui, P., Guo, H., Xu, P., Liu, L., Iwasaki, M., Shimazu, T., Tsugane, S., Zhu, J., Jiang, G., Fei, K., Park, J. Y., Kim, Y. H., Sung, J. S., Park, K. H., Kim, Y. T., Jung, Y. J., Kang, C. H., Park, I. K., Kim, H. N., Jeon, H. S., Choi, J. E., Choi, Y. Y., Kim, J. H., Oh, I. J., Kim, Y. C., Sung, S. W., Kim, J. S., Yoon, H. I., Kweon, S. S., Shin, M. H., Seow, A., Chen, Y., Lim, W. Y., Liu, J., Wong, M. P., Lee, V. H. F., Bassig, B. A., Tucker, M., Berndt, S. I., Chow, W. H., Ji, B. T., Wang, J., Xu, J., Sihoe, A. D. L., Ho, J. C. M., Chan, J. K. C., Wang, J. C., Lu, D., Zhao, X., Zhao, Z., Wu, J., Chen, H., Jin, L., Wei, F., Wu, G., An, S. J., Zhang, X. C., Su, J., Wu, Y. L., Gao, Y. T., Xiang, Y. B., He, X., Li, J., Zheng, W., Shu, X. O., Cai, Q., Klein, R., Pao, W., Lawrence, C., Hosgood, H. D., Hsiao, C. F., Chien, L. H., Chen, Y. H., Chen, C. H., Wang, W. C., Chen, C. Y., Wang, C. L., Yu, C. J., Chen, H. L., Su, Y. C., Tsai, F. Y., Chen, Y. S., Li, Y. J., Yang, T. Y., Lin, C. C., Yang, P. C., Wu, T., Lin, D., Zhou, B., Yu, J., Shen, H., Kubo, M., Chanock, S. J., Rothman, N. & Lan, Q., 01-02-2016, In : Human molecular genetics. 25, 3, p. 620-629 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Methotrexate inhibits osteoclastogenesis by decreasing RANKL-induced calcium influx into osteoclast progenitors

Kanagawa, H., Masuyama, R., Morita, M., Sato, Y., Niki, Y., Kobayashi, T., Katsuyama, E., Fujie, A., Hao, W., Tando, T., Watanabe, R., Miyamoto, K., Morioka, H., Matsumoto, M., Toyama, Y., Saya, H. & Miyamoto, T., 01-09-2016, In : Journal of Bone and Mineral Metabolism. 34, 5, p. 526-531 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Molecular mechanism linking BDNF/TrkB signaling with the NMDA receptor in memory: The role of Girdin in the CNS

Itoh, N., Enomoto, A., Nagai, T., Takahashi, M. & Yamada, K., 01-07-2016, In : Reviews in the Neurosciences. 27, 5, p. 481-490 10 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)

Myeloid differentiation factor 88 signaling in bone marrow-derived cells promotes gastric tumorigenesis by generation of inflammatory microenvironment

Maeda, Y., Echizen, K., Oshima, H., Yu, L., Sakulsak, N., Hirose, O., Yamada, Y., Taniguchi, T., Jenkins, B. J., Saya, H. & Oshima, M., 03-2016, In : Cancer Prevention Research. 9, 3, p. 253-263 11 p.

Research output: Contribution to journalArticle

Open Access
20 Citations (Scopus)

Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein-Aurora A pathway

Inaba, H., Goto, H., Kasahara, K., Kumamoto, K., Yonemura, S., Inoko, A., Yamano, S., Wanibuchi, H., He, D., Goshima, N., Kiyono, T., Hirotsune, S. & Inagaki, M., 2016, In : Journal of Cell Biology. 212, 4, p. 409-423 15 p.

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30 Citations (Scopus)

Negative regulation of microRNA-132 in expression of synaptic proteins in neuronal differentiation of embryonic neural stem cells

Yoshimura, A., Numakawa, T., Odaka, H., Adachi, N., Tamai, Y. & Kunugi, H., 01-07-2016, In : Neurochemistry International. 97, p. 26-33 8 p.

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17 Citations (Scopus)

NR0B1 Frameshift Mutation in a Boy with Idiopathic Central Precocious Puberty

Shima, H., Yatsuga, S., Nakamura, A., Sano, S., Sasaki, T., Katsumata, N., Suzuki, E., Hata, K., Nakabayashi, K., Momozawa, Y., Kubo, M., Okamura, K., Kure, S., Matsubara, Y., Ogata, T., Narumi, S. & Fukami, M., 01-10-2016, In : Sexual Development. 10, 4, p. 205-209 5 p.

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3 Citations (Scopus)

Pharmacogenetic discovery in CALGB (alliance) 90401 and mechanistic validation of a VAC14 polymorphism that increases risk of docetaxel-induced neuropathy

Hertz, D. L., Owzar, K., Lessans, S., Wing, C., Jiang, C., Kelly, W. K., Patel, J., Halabi, S., Furukawa, Y., Wheeler, H. E., Sibley, A. B., Lassiter, C., Weisman, L., Watson, D., Krens, S. D., Mulkey, F., Renn, C. L., Small, E. J., Febbo, P. G., Shterev, I. & 12 others, Kroetz, D. L., Friedman, P. N., Mahoney, J. F., Carducci, M. A., Kelley, M. J., Nakamura, Y., Kubo, M., Dorsey, S. G., Dolan, M. E., Morris, M. J., Ratain, M. J. & McLeod, H. L., 01-10-2016, In : Clinical Cancer Research. 22, 19, p. 4890-4900 11 p.

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25 Citations (Scopus)

Pharmacogenomic Study of Clozapine-Induced Agranulocytosis/Granulocytopenia in a Japanese Population

Saito, T., Ikeda, M., Mushiroda, T., Ozeki, T., Kondo, K., Shimasaki, A., Kawase, K., Hashimoto, S., Yamamori, H., Yasuda, Y., Fujimoto, M., Ohi, K., Takeda, M., Kamatani, Y., Numata, S., Ohmori, T., Ueno, S. I., Makinodan, M., Nishihata, Y., Kubota, M. & 17 others, Kimura, T., Kanahara, N., Hashimoto, N., Fujita, K., Nemoto, K., Fukao, T., Suwa, T., Noda, T., Yada, Y., Takaki, M., Kida, N., Otsuru, T., Murakami, M., Takahashi, A., Kubo, M., Hashimoto, R. & Iwata, N., 15-10-2016, In : Biological Psychiatry. 80, 8, p. 636-642 7 p.

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35 Citations (Scopus)

Phosphorylation Signals in Striatal Medium Spiny Neurons

Nagai, T., Yoshimoto, J., Kannon, T., Kuroda, K. & Kaibuchi, K., 01-10-2016, In : Trends in Pharmacological Sciences. 37, 10, p. 858-871 14 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)

PKCη deficiency improves lipid metabolism and atherosclerosis in apolipoprotein E-deficient mice

Torisu, K., Zhang, X., Nonaka, M., Kaji, T., Tsuchimoto, D., Kajitani, K., Sakumi, K., Torisu, T., Chida, K., Sueishi, K., Kubo, M., Hata, J., Kitazono, T., Kiyohara, Y. & Nakabeppu, Y., 01-10-2016, In : Genes to Cells. 21, 10, p. 1030-1048 19 p.

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5 Citations (Scopus)

Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex

Aoyama, Y., Toriumi, K., Mouri, A., Hattori, T., Ueda, E., Shimato, A., Sakakibara, N., Soh, Y., Mamiya, T., Nagai, T., Kim, H. C., Hiramatsu, M., Nabeshima, T. & Yamada, K., 01-01-2016, In : Neuropsychopharmacology. 41, 2, p. 578-589 12 p.

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24 Citations (Scopus)

Reassortment of human and animal rotavirus gene segments in emerging DS-1-like G1P[8] rotavirus strains

Komoto, S., Tacharoenmuang, R., Guntapong, R., Ide, T., Tsuji, T., Yoshikawa, T., Tharmaphornpilas, P., Sangkitporn, S. & Taniguchi, K., 01-02-2016, In : PloS one. 11, 2, e0148416.

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42 Citations (Scopus)