Research Promotion and Support Headquarters

Research Output

2014

Changes in serum growth factors in stroke rehabilitation patients and their relation to hemiparesis improvement

Okazaki, H., Beppu, H., Mizutani, K., Okamoto, S. & Sonoda, S., 01-01-2014, In : Journal of Stroke and Cerebrovascular Diseases. 23, 6, p. 1703-1708 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Characteristics of Japanese inflammatory bowel disease susceptibility loci

Arimura, Y., Isshiki, H., Onodera, K., Nagaishi, K., Yamashita, K., Sonoda, T., Matsumoto, T., Takahashi, A., Takazoe, M., Yamazaki, K., Kubo, M., Fujimiya, M., Imai, K. & Shinomura, Y., 08-2014, In : Journal of Gastroenterology. 49, 8, p. 1217-1230 14 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Citalopram and escitalopram plasma drug and metabolite concentrations: Genome-wide associations

Ji, Y., Schaid, D. J., Desta, Z., Kubo, M., Batzler, A. J., Snyder, K., Mushiroda, T., Kamatani, N., Ogburn, E., Hall-Flavin, D., Flockhart, D., Nakamura, Y., Mrazek, D. A. & Weinshilboum, R. M., 08-2014, In : British Journal of Clinical Pharmacology. 78, 2, p. 373-383 11 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor

Aoyama, Y., Mouri, A., Toriumi, K., Koseki, T., Narusawa, S., Ikawa, N., Mamiya, T., Nagai, T., Yamada, K. & Nabeshima, T., 05-2014, In : International Journal of Neuropsychopharmacology. 17, 5, p. 723-737 15 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Comprehensive analysis of melanogenesis and proliferation potential of melanocyte lineage in solar lentigines

Yamada, T., Hasegawa, S., Inoue, Y., Date, Y., Arima, M., Yagami, A., Iwata, Y., Abe, M., Takahashi, M., Yamamoto, N., Mizutani, H., Nakata, S., Matsunaga, K. & Akamatsu, H., 01-03-2014, In : Journal of Dermatological Science. 73, 3, p. 251-257 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Conserved neutralizing epitope at globular head of hemagglutinin in H3N2 influenza viruses

Iba, Y., Fujii, Y., Ohshima, N., Sumida, T., Kubota-Koketsu, R., Ikeda, M., Wakiyama, M., Shirouzu, M., Okada, J., Okuno, Y., Kurosawa, Y. & Yokoyama, S., 2014, In : Journal of Virology. 88, 13, p. 7130-7144 15 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Construction and molecular characterization of a T-cell receptor-like antibody and CAR-T cells specific for minor histocompatibility antigen HA-1H

Inaguma, Y., Akahori, Y., Murayama, Y., Shiraishi, K., Tsuzuki-Iba, S., Endoh, A., Tsujikawa, J., Demachi-Okamura, A., Hiramatsu, K., Saji, H., Yamamoto, Y., Yamamoto, N., Nishimura, Y., Takahashi, T., Kuzushima, K., Emi, N. & Akatsuka, Y., 06-2014, In : Gene therapy. 21, 6, p. 575-584 10 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Cytoskeletal Regulation by AUTS2 in Neuronal Migration and Neuritogenesis

Hori, K., Nagai, T., Shan, W., Sakamoto, A., Taya, S., Hashimoto, R., Hayashi, T., Abe, M., Yamazaki, M., Nakao, K., Nishioka, T., Sakimura, K., Yamada, K., Kaibuchi, K. & Hoshino, M., 24-12-2014, In : Cell Reports. 9, 6, p. 2166-2179 14 p.

Research output: Contribution to journalArticle

Open Access
42 Citations (Scopus)

Development of a SNP set for human identification: A set with high powers of discrimination which yields high genetic information from naturally degraded DNA samples in the Thai population

Boonyarit, H., Mahasirimongkol, S., Chavalvechakul, N., Aoki, M., Amitani, H., Hosono, N., Kamatani, N., Kubo, M. & Lertrit, P., 07-2014, In : Forensic Science International: Genetics. 11, 1, p. 166-173 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Effects of edaravone, a radical scavenger, on hepatocyte transplantation

Hayashi, C., Ito, M., Ito, R., Murakumo, A., Yamamoto, N., Hiramatsu, N., Fox, I. J. & Horiguchi, A., 01-12-2014, In : Journal of Hepato-Biliary-Pancreatic Sciences. 21, 12, p. 919-924 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Erratum: Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin (Clinical Pharmacology and Therapeutics (2014) 96:3 (370-379) DOI:10.1038/clpt.2014.109)

Goswami, S., Yee, S. W., Stocker, S., Mosley, J. D., Kubo, M., Castro, R., Mefford, J. A., Wen, C., Liang, X., Witte, J., Brett, C., Maeda, S., Simpson, M. D., Hedderson, M. M., Davis, R. L., Roden, D. M., Giacomini, K. M. & Savic, R. M., 11-2014, In : Clinical Pharmacology and Therapeutics. 96, 5, 1 p.

Research output: Contribution to journalComment/debate

Erratum: Impact of PSCAVariation on Gastric Ulcer Susceptibility (PLoS ONE (2013) 8:5 (e63698) DOI:10.1371/journal.pone.0063698)

Tanikawa, C., Matsuo, K., Kubo, M., Takahashi, A. & Ito, H., 05-12-2014, In : PloS one. 9, 12, A48.

Research output: Contribution to journalComment/debate

Establishment of CYP2D6 reference samples by multiple validated genotyping platforms

Fang, H., Liu, X., Ramírez, J., Choudhury, N., Kubo, M., Im, H. K., Konkashbaev, A., Cox, N. J., Ratain, M. J., Nakamura, Y. & O'Donnell, P. H., 11-12-2014, In : Pharmacogenomics Journal. 14, 6, p. 564-572 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Expression of truncated PITX3 in the developing lens leads to microphthalmia and aphakia in mice

Wada, K., Matsushima, Y., Tada, T., Hasegawa, S., Obara, Y., Yoshizawa, Y., Takahashi, G., Hiai, H., Shimanuki, M., Suzuki, S., Saitou, J., Yamamoto, N., Ichikawa, M., Watanabe, K. & Kikkawa, Y., 27-10-2014, In : PloS one. 9, 10, e111432.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Functional recovery and alterations in the expression and localization of protein kinase C following voluntary exercise in rat with cerebral infarction

Mizutani, K., Sonoda, S., Wakita, H., Katoh, Y. & Shimpo, K., 01-01-2014, In : Neurological Sciences. 35, 1, p. 53-59 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals: Data from the J-MICC Study

Hishida, A., Takashima, N., Turin, T. C., Kawai, S., Wakai, K., Hamajima, N., Hosono, S., Nishida, Y., Suzuki, S., Nakahata, N., Mikami, H., Ohnaka, K., Matsui, D., Katsuura-Kamano, S., Kubo, M., Tanaka, H. & Kita, Y., 04-2014, In : Journal of Nephrology. 27, 2, p. 143-149 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids

Park, H. W., Dahlin, A., Tse, S., Duan, Q. L., Schuemann, B., Martinez, F. D., Peters, S. P., Szefler, S. J., Lima, J. J., Kubo, M., Tamari, M. & Tantisira, K. G., 03-2014, In : Journal of Allergy and Clinical Immunology. 133, 3, p. 664-669.e5

Research output: Contribution to journalArticle

48 Citations (Scopus)

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Okada, Y., Wu, D., Trynka, G., Raj, T., Terao, C., Ikari, K., Kochi, Y., Ohmura, K., Suzuki, A., Yoshida, S., Graham, R. R., Manoharan, A., Ortmann, W., Bhangale, T., Denny, J. C., Carroll, R. J., Eyler, A. E., Greenberg, J. D., Kremer, J. M., Pappas, D. A. & 75 others, Jiang, L., Yin, J., Ye, L., Su, D. F., Yang, J., Xie, G., Keystone, E., Westra, H. J., Esko, T., Metspalu, A., Zhou, X., Gupta, N., Mirel, D., Stahl, E. A., Diogo, D., Cui, J., Liao, K., Guo, M. H., Myouzen, K., Kawaguchi, T., Coenen, M. J. H., Van Riel, P. L. C. M., Van De Laar, M. A. F. J., Guchelaar, H. J., Huizinga, T. W. J., Dieudé, P., Mariette, X., Bridges, S. L., Zhernakova, A., Toes, R. E. M., Tak, P. P., Miceli-Richard, C., Bang, S. Y., Lee, H. S., Martin, J., Gonzalez-Gay, M. A., Rodriguez-Rodriguez, L., Rantapää-Dahlqvist, S., Ärlestig, L., Choi, H. K., Kamatani, Y., Galan, P., Lathrop, M., Eyre, S., Bowes, J., Barton, A., De Vries, N., Moreland, L. W., Criswell, L. A., Karlson, E. W., Taniguchi, A., Yamada, R., Kubo, M., Liu, J. S., Bae, S. C., Worthington, J., Padyukov, L., Klareskog, L., Gregersen, P. K., Raychaudhuri, S., Stranger, B. E., De Jager, P. L., Franke, L., Visscher, P. M., Brown, M. A., Yamanaka, H., Mimori, T., Takahashi, A., Xu, H., Behrens, T. W., Siminovitch, K. A., Momohara, S., Matsuda, F., Yamamoto, K. & Plenge, R. M., 07-01-2014, In : Nature. 506, 7488, p. 376-381 6 p.

Research output: Contribution to journalArticle

924 Citations (Scopus)

Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin

Goswami, S., Yee, S. W., Stocker, S., Mosley, J. D., Kubo, M., Castro, R., Mefford, J. A., Wen, C., Liang, X., Witte, J., Brett, C., Maeda, S., Simpson, M. D., Hedderson, M. M., Davis, R. L., Roden, D. M., Giacomini, K. M. & Savic, R. M., 09-2014, In : Clinical Pharmacology and Therapeutics. 96, 3, p. 370-379 10 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1

Cai, Q., Zhang, B., Sung, H., Low, S. K., Kweon, S. S., Lu, W., Shi, J., Long, J., Wen, W., Choi, J. Y., Noh, D. Y., Shen, C. Y., Matsuo, K., Teo, S. H., Kim, M. K., Khoo, U. S., Iwasaki, M., Hartman, M., Takahashi, A., Ashikawa, K. & 31 others, Matsuda, K., Shin, M. H., Park, M. H., Zheng, Y., Xiang, Y. B., Ji, B. T., Park, S. K., Wu, P. E., Hsiung, C. N., Ito, H., Kasuga, Y., Kang, P., Mariapun, S., Ahn, S. H., Kang, H. S., Chan, K. Y. K., Man, E. P. S., Iwata, H., Tsugane, S., Miao, H., Liao, J., Nakamura, Y., Kubo, M., Delahanty, R. J., Zhang, Y., Li, B., Li, C., Gao, Y. T., Shu, X. O., Kang, D. & Zheng, W., 08-2014, In : Nature Genetics. 46, 8, p. 886-890 5 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)

Genome-wide association study: A useful tool to identify common genetic variants associated with drug toxicity and efficacy in cancer pharmacogenomics

Low, S. K., Takahashi, A., Mushiroda, T. & Kubo, M., 15-05-2014, In : Clinical Cancer Research. 20, 10, p. 2541-2552 12 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians

Zhang, B., Jia, W. H., Matsuo, K., Shin, A., Xiang, Y. B., Matsuda, K., Jee, S. H., Kim, D. H., Cheah, P. Y., Ren, Z., Cai, Q., Long, J., Shi, J., Wen, W., Yang, G., Ji, B. T., Pan, Z. Z., Matsuda, F., Gao, Y. T., Oh, J. H. & 13 others, Ahn, Y. O., Kubo, M., Thean, L. F., Park, E. J., Li, H. L., Park, J. W., Jo, J., Jeong, J. Y., Hosono, S., Nakamura, Y., Shu, X. O., Zeng, Y. X. & Zheng, W., 15-08-2014, In : International Journal of Cancer. 135, 4, p. 948-955 8 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Genome-wide association study identifies three novel loci for type 2 diabetes

Hara, K., Fujita, H., Johnson, T. A., Yamauchi, T., Yasuda, K., Horikoshi, M., Peng, C., Hu, C., Ma, R. C. W., Imamura, M., Iwata, M., Tsunoda, T., Morizono, T., Shojima, N., So, W. Y., Leung, T. F., Kwan, P., Zhang, R., Wang, J., Yu, W. & 17 others, Maegawa, H., Hirose, H., Kaku, K., Ito, C., Watada, H., Tanaka, Y., Tobe, K., Kashiwagi, A., Kawamori, R., Jia, W., Chan, J. C. N., Teo, Y. Y., Shyong, T. E., Kamatani, N., Kubo, M., Maeda, S. & Kadowaki, T., 01-01-2014, In : Human molecular genetics. 23, 1, p. 239-246 8 p., ddt399.

Research output: Contribution to journalArticle

99 Citations (Scopus)

Girdin phosphorylation is crucial for synaptic plasticity and memory: A potential role in the interaction of BDNF/TrkB/ Akt signaling with NMDA receptor

Nakai, T., Nagai, T., Tanaka, M., Itoh, N., Asai, N., Enomoto, A., Asai, M., Yamada, S., Saifullah, A. B., Sokabe, M., Takahashi, M. & Yamada, K., 05-11-2014, In : Journal of Neuroscience. 34, 45, p. 14995-15008 14 p.

Research output: Contribution to journalArticle

Open Access
47 Citations (Scopus)

Human monoclonal antibodies - A dual advantaged weapon to tackle cancer and viruses

Kurosawa, G., 01-01-2014, In : Journal of Stem Cells and Regenerative Medicine. 10, 2, 1 p.

Research output: Contribution to journalArticle

Identification and characterization of PDGFR + mesenchymal progenitors in human skeletal muscle

Uezumi, A., Fukada, S., Yamamoto, N., Ikemoto-Uezumi, M., Nakatani, M., Morita, M., Yamaguchi, A., Yamada, H., Nishino, I., Hamada, Y. & Tsuchida, K., 04-2014, In : Cell Death and Disease. 5, 4, e1186.

Research output: Contribution to journalArticle

104 Citations (Scopus)

Identification of a gene for an ancient cytokine, interleukin 15-like, in mammals; interleukins 2 and 15 co-evolved with this third family member, all sharing binding motifs for IL-15Rα

Dijkstra, J. M., Takizawa, F., Fischer, U., Friedrich, M., Soto-Lampe, V., Lefèvre, C., Lenk, M., Karger, A., Matsui, T. & Hashimoto, K., 02-2014, In : Immunogenetics. 66, 2, p. 93-103 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

IFNL4/IL-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population

Ochi, H., Miki, D., Nelson Hayes, C., Abe, H., Hayashida, Y., Kubo, M. & Chayama, K., 06-2014, In : Journal of General Virology. 95, PART 6, p. 1297-1306 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Induction of interferon-induced transmembrane protein 3 gene expression by lipopolysaccharide in astrocytes

Nakajima, A., Ibi, D., Nagai, T., Yamada, S., Nabeshima, T. & Yamada, K., 15-12-2014, In : European Journal of Pharmacology. 745, p. 166-175 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics

Wu, A. C., Himes, B. E., Lasky-Su, J., Litonjua, A., Peters, S. P., Lima, J., Kubo, M., Tamari, M., Nakamura, Y., Qiu, W., Weiss, S. T. & Tantisira, K., 03-2014, In : Journal of Allergy and Clinical Immunology. 133, 3, p. 723-728.e3

Research output: Contribution to journalArticle

11 Citations (Scopus)

In situ visualization of plasma cells producing antibodies reactive to Porphyromonas gingivalis in periodontitis: The application of the enzyme-labeled antigen method

Mizutani, Y., Tsuge, S., Takeda, H., Hasegawa, Y., Shiogama, K., Onouchi, T., Inada, K., Sawasaki, T. & Tsutsumi, Y., 08-2014, In : Molecular Oral Microbiology. 29, 4, p. 156-173 18 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers

Shiraishi, Y., Fujimoto, A., Furuta, M., Tanaka, H., Chiba, K. I., Boroevich, K. A., Abe, T., Kawakami, Y., Ueno, M., Gotoh, K., Ariizumi, S. I., Shibuya, T., Nakano, K., Sasaki, A., Maejima, K., Kitada, R., Hayami, S., Shigekawa, Y., Marubashi, S., Yamada, T. & 11 others, Kubo, M., Ishikawa, O., Aikata, H., Arihiro, K., Ohdan, H., Yamamoto, M., Yamaue, H., Chayama, K., Tsunoda, T., Miyano, S. & Nakagawa, H., 19-12-2014, In : PloS one. 9, 12, e114263.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

Sinner, M. F., Tucker, N. R., Lunetta, K. L., Ozaki, K., Smith, J. G., Trompet, S., Bis, J. C., Lin, H., Chung, M. K., Nielsen, J. B., Lubitz, S. A., Krijthe, B. P., Magnani, J. W., Ye, J., Gollob, M. H., Tsunoda, T., Müller-Nurasyid, M., Lichtner, P., Peters, A., Dolmatova, E. & 35 others, Kubo, M., Smith, J. D., Psaty, B. M., Smith, N. L., Jukema, J. W., Chasman, D. I., Albert, C. M., Ebana, Y., Furukawa, T., Macfarlane, P. W., Harris, T. B., Darbar, D., Dörr, M., Holst, A. G., Svendsen, J. H., Hofman, A., Uitterlinden, A. G., Gudnason, V., Isobe, M., Malik, R., Dichgans, M., Rosand, J., Van Wagoner, D. R., Benjamin, E. J., Milan, D. J., Melander, O., Heckbert, S. R., Ford, I., Liu, Y., Barnard, J., Olesen, M. S., Stricker, B. H. C., Tanaka, T., Kääb, S. & Ellinor, P. T., 01-01-2014, In : Circulation. 130, 15, p. 1225-1235 11 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)

Large-scale genetic study in east Asians identifies six new loci associated with colorectal cancer risk

Zhang, B., Jia, W. H., Matsuda, K., Kweon, S. S., Matsuo, K., Xiang, Y. B., Shin, A., Jee, S. H., Kim, D. H., Cai, Q., Long, J., Shi, J., Wen, W., Yang, G., Zhang, Y., Li, C., Li, B., Guo, Y., Ren, Z., Ji, B. T. & 25 others, Pan, Z. Z., Takahashi, A., Shin, M. H., Matsuda, F., Gao, Y. T., Oh, J. H., Kim, S., Ahn, Y. O., Chan, A. T., Chang-Claude, J., Slattery, M. L., Gruber, S. B., Schumacher, F. R., Stenzel, S. L., Casey, G., Kim, H. R., Jeong, J. Y., Park, J. W., Li, H. L., Hosono, S., Cho, S. H., Kubo, M., Shu, X. O., Zeng, Y. X. & Zheng, W., 06-2014, In : Nature Genetics. 46, 6, p. 533-542 10 p.

Research output: Contribution to journalArticle

147 Citations (Scopus)

Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in cancer cells and promote redox adaptation

Ishimoto, T., Sugihara, H., Watanabe, M., Sawayama, H., Iwatsuki, M., Baba, Y., Okabe, H., Hidaka, K., Yokoyama, N., Miyake, K., Yoshikawa, M., Nagano, O., Komohara, Y., Takeya, M., Saya, H. & Baba, H., 04-2014, In : Carcinogenesis. 35, 5, p. 1003-1011 9 p.

Research output: Contribution to journalArticle

Open Access
54 Citations (Scopus)

Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

Wen, W., Zheng, W., Okada, Y., Takeuchi, F., Tabara, Y., Hwang, J. Y., Dorajoo, R., Li, H., Tsai, F. J., Yang, X., He, J., Wu, Y., He, M., Zhang, Y., Liang, J., Guo, X., Sheu, W. H. U. H., Delahanty, R., Guo, X., Kubo, M. & 89 others, Yamamoto, K., Ohkubo, T., Go, M. J. I., Liu, J. J. U., Gan, W., Chen, C. C., Gao, Y., Li, S., Lee, N. R., Wu, C., Zhou, X., Song, H., Yao, J., Lee, I. T., Long, J., Tsunoda, T., Akiyama, K., Takashima, N., Cho, Y. S. H., Ong, R. T. H., Lu, L., Chen, C. H., Tan, A., Rice, T. K., Adair, L. S., Gui, L., Allison, M., Lee, W. J., Cai, Q., Isomura, M., Umemura, S., Kim, Y. J. I., Seielstad, M., Hixson, J., Xiang, Y. B., Isono, M., Kim, B. J., Sim, X., Lu, W., Nabika, T., Lee, J., Lim, W. Y., Gao, Y. T., Takayanagi, R., Kang, D. H., Wong, T. Y. I., Hsiung, C. A. G., Wu, I. C., Juang, J. M. J. I., Shi, J., Choi, B. Y. O., Aung, T., Hu, F., Kim, M. K. Y., Lim, W. Y. E., Wang, T. D., Shin, M. H., Lee, J., Ji, B. T., Lee, Y. H., Young, T. L., Shin, D. H. O., Chun, B. Y., Cho, M. C., Han, B. G., Hwu, C. M., Assimes, T. L., Absher, D., Yan, X., Kim, E., Kuo, J. Z., Kwon, S., Taylor, K. D., Chen, Y. D. I., Rotter, J. I., Qi, L., Zhu, D., Wu, T., Mohlke, K. L., Gu, D., Mo, Z., Wu, J. Y., Lin, X., Miki, T., Tai, E. S., Lee, J. Y., Kato, N., Shu, X. O. & Tanaka, T., 15-10-2014, In : Human molecular genetics. 23, 20, p. 5492-5504 13 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)

Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians

Chen, P., Takeuchi, F., Lee, J. Y., Li, H., Wu, J. Y., Liang, J., Long, J., Tabara, Y., Goodarzi, M. O., Pereira, M. A., Kim, Y. J., Go, M. J., Stram, D. O., Vithana, E., Khor, C. C., Liu, J., Liao, J., Ye, X., Wang, Y., Lu, L. & 50 others, Young, T. L., Lee, J., Thai, A. C., Cheng, C. Y., Van Dam, R. M., Friedlander, Y., Heng, C. K., Koh, W. P., Chen, C. H., Chang, L. C., Pan, W. H., Qi, B., Isono, M., Zheng, W., Cai, Q., Gao, Y., Yamamoto, K., Ohnaka, K., Takayanagi, R., Kita, Y., Ueshima, H., Hsiung, C. A., Cui, J., Sheu, W. H. H., Rotter, J. I., Chen, Y. D. I., Hsu, C., Okada, Y., Kubo, M., Takahashi, A., Tanaka, T., Van Rooij, F. J. A., Ganesh, S. K., Huang, J., Huang, T., Yuan, J., Hwang, J. Y., Gross, M. D., Assimes, T. L., Miki, T., Shu, X. O., Qi, L., Chen, Y. T., Lin, X., Aung, T., Wong, T. Y., Teo, Y. Y., Kim, B. J., Kato, N. & Tai, E. S., 07-2014, In : Diabetes. 63, 7, p. 2551-2562 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

Lubitz, S. A., Lunetta, K. L., Lin, H., Arking, D. E., Trompet, S., Li, G., Krijthe, B. P., Chasman, D. I., Barnard, J., Kleber, M. E., Dörr, M., Ozaki, K., Smith, A. V., Müller-Nurasyid, M., Walter, S., Agarwal, S. K., Bis, J. C., Brody, J. A., Chen, L. Y., Everett, B. M. & 42 others, Ford, I., Franco, O. H., Harris, T. B., Hofman, A., Kääb, S., Mahida, S., Kathiresan, S., Kubo, M., Launer, L. J., Macfarlane, P. W., Magnani, J. W., McKnight, B., McManus, D. D., Peters, A., Psaty, B. M., Rose, L. M., Rotter, J. I., Silbernagel, G., Smith, J. D., Sotoodehnia, N., Stott, D. J., Taylor, K. D., Tomaschitz, A., Tsunoda, T., Uitterlinden, A. G., Van Wagoner, D. R., Völker, U., Völzke, H., Murabito, J. M., Sinner, M. F., Gudnason, V., Felix, S. B., März, W., Chung, M., Albert, C. M., Stricker, B. H., Tanaka, T., Heckbert, S. R., Jukema, J. W., Alonso, A., Benjamin, E. J. & Ellinor, P. T., 01-04-2014, In : Journal of the American College of Cardiology. 63, 12, p. 1200-1210 11 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Npas4 regulates Mdm2 and thus Dcx in experience-dependent dendritic spine development of newborn olfactory bulb interneurons

Yoshihara, S. I., Takahashi, H., Nishimura, N., Kinoshita, M., Asahina, R., Kitsuki, M., Tatsumi, K., Furukawa-Hibi, Y., Hirai, H., Nagai, T., Yamada, K. & Tsuboi, A., 07-08-2014, In : Cell Reports. 8, 3, p. 843-857 15 p.

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Plasma dehydroepiandrosterone sulfate levels in patients with major depressive disorder correlate with remission during treatment with antidepressants

Morita, T., Senzaki, K., Ishihara, R., Umeda, K., Iwata, N., Nagai, T., Hida, H., Nabeshima, T., Yukawa, K., Ozaki, N. & Noda, Y., 05-2014, In : Human Psychopharmacology. 29, 3, p. 280-286 7 p.

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10 Citations (Scopus)

Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance)

Chhibber, A., Mefford, J., Stahl, E. A., Pendergrass, S. A., Baldwin, R. M., Owzar, K., Li, M., Winer, E. P., Hudis, C. A., Zembutsu, H., Kubo, M., Nakamura, Y., McLeod, H. L., Ratain, M. J., Shulman, L. N., Ritchie, M. D., Plenge, R. M., Witte, J. S. & Kroetz, D. L., 08-2014, In : Pharmacogenomics Journal. 14, 4, p. 336-342 7 p.

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17 Citations (Scopus)

Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese - Cross-sectional data from the J-MICC study

Hishida, A., Wakai, K., Naito, M., Suma, S., Sasakabe, T., Hamajima, N., Hosono, S., Horita, M., Turin, T. C., Suzuki, S., Kairupan, T. S., Mikami, H., Ohnaka, K., Watanabe, I., Uemura, H., Kubo, M. & Tanaka, H., 14-10-2014, In : Lipids in Health and Disease. 13, 1, 162.

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3 Citations (Scopus)

Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus

Lee, P. S., Ohshima, N., Stanfield, R. L., Yu, W., Iba, Y., Okuno, Y., Kurosawa, Y. & Wilson, I. A., 10-04-2014, In : Nature Communications. 5, 3614.

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86 Citations (Scopus)

Renal cyclooxygenase products are higher and lipoxygenase products are lower in early disease in the pcy mouse model of adolescent nephronophthisis

Yamaguchi, T., Lysecki, C., Reid, A., Nagao, S. & Aukema, H. M., 01-01-2014, In : Lipids. 49, 1, p. 39-47 9 p.

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5 Citations (Scopus)

Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia

Onouchi, T., Kobayashi, K., Sakai, K., Shimomura, A., Smits, R., Sumi-Ichinose, C., Kurosumi, M., Takao, K., Nomura, R., Iizuka-Kogo, A., Suzuki, H., Kondo, K., Akiyama, T., Miyakawa, T., Fodde, R. & Senda, T., 29-03-2014, In : Molecular brain. 7, 1, 21.

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18 Citations (Scopus)

The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort

Shigemizu, D., Abe, T., Morizono, T., Johnson, T. A., Boroevich, K. A., Hirakawa, Y., Ninomiya, T., Kiyohara, Y., Kubo, M., Nakamura, Y., Maeda, S. & Tsunoda, T., 20-03-2014, In : PloS one. 9, 3, e92549.

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The effect of sevoflurane on developing A/J strain mouse embryos using a whole-embryo culture system - The incidence of cleft lip in culture embryos

Yamada, M., Yamamoto, N., Ohgami, S., Kanazawa, M., Harada, J., Ohno, N. & Natsume, N., 03-2014, In : In Vitro Cellular and Developmental Biology - Animal. 50, 3, p. 237-242 6 p.

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2 Citations (Scopus)

Trans-ethnic meta-analysis of white blood cell phenotypes

CHARGE Hematology, COGENT & BioBank Japan Project (RIKEN) Working Groups, 20-12-2014, In : Human molecular genetics. 23, 25, p. 6944-6960 17 p.

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27 Citations (Scopus)

Two types of antibodies are induced by vaccination with A/California/2009pdm virus: Binding near the sialic acid-binding pocket and neutralizing both H1N1 and H5N1 viruses

Ohshima, N., Kubota-Koketsu, R., Iba, Y., Okuno, Y. & Kurosawa, Y., 05-02-2014, In : PloS one. 9, 2, e87305.

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7 Citations (Scopus)