Research Promotion and Support Headquarters

Research Output

2013

A genome-wide association study identifies 2 susceptibility loci for crohn's disease in a Japanese population

Yamazaki, K., Umeno, J., Takahashi, A., Hirano, A., Johnson, T. A., Kumasaka, N., Morizono, T., Hosono, N., Kawaguchi, T., Takazoe, M., Yamada, T., Suzuki, Y., Tanaka, H., Motoya, S., Hosokawa, M., Arimura, Y., Shinomura, Y., Matsui, T., Matsumoto, T., Iida, M. & 4 others, Tsunoda, T., Nakamura, Y., Kamatani, N. & Kubo, M., 04-2013, In : Gastroenterology. 144, 4, p. 781-788 8 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients

Chung, S., Low, S. K., Zembutsu, H., Takahashi, A., Kubo, M., Sasa, M. & Nakamura, Y., 11-09-2013, In : Breast Cancer Research. 15, 5, R81.

Research output: Contribution to journalArticle

17 Citations (Scopus)

A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region

Urabe, Y., Ochi, H., Kato, N., Kumar, V., Takahashi, A., Muroyama, R., Hosono, N., Otsuka, M., Tateishi, R., Lo, P. H. Y., Tanikawa, C., Omata, M., Koike, K., Miki, D., Abe, H., Kamatani, N., Toyota, J., Kumada, H., Kubo, M., Chayama, K. & 2 others, Nakamura, Y. & Matsuda, K., 01-05-2013, In : Journal of Hepatology. 58, 5, p. 875-882 8 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: Effects of *09:01 allele on disease phenotypes

Shimane, K., Kochi, Y., Suzuki, A., Okada, Y., Ishii, T., Horita, T., Saito, K., Okamoto, A., Nishimoto, N., Myouzen, K., Kubo, M., Hirakata, M., Sumida, T., Takasaki, Y., Yamada, R., Nakamura, Y., Kamatani, N. & Yamamoto, K., 01-07-2013, In : Rheumatology (United Kingdom). 52, 7, p. 1172-1182 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

A practical method to detect SNVs and indels from whole genome and exome sequencing data

Shigemizu, D., Fujimoto, A., Akiyama, S., Abe, T., Nakano, K., Boroevich, K. A., Yamamoto, Y., Furuta, M., Kubo, M., Nakagawa, H. & Tsunoda, T., 23-07-2013, In : Scientific reports. 3, 2161.

Research output: Contribution to journalArticle

23 Citations (Scopus)

A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population

Yasui, T., Okada, A., Urabe, Y., Usami, M., Mizuno, K., Kubota, Y., Tozawa, K., Sasaki, S., Higashi, Y., Sato, Y., Kubo, M., Nakamura, Y., Matsuda, K. & Kohri, K., 01-09-2013, In : Journal of Human Genetics. 58, 9, p. 588-593 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Arf and p53 act as guardians of a quiescent cellular state by protecting against immortalization of cells with stable genomes

Osawa, T., Atsumi, Y., Sugihara, E., Saya, H., Kanno, M., Tashiro, F., Masutani, M. & Yoshioka, K. I., 01-03-2013, In : Biochemical and Biophysical Research Communications. 432, 1, p. 34-39 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Association study of 71 European Crohn's disease susceptibility loci in a Japanese population

Hirano, A., Yamazaki, K., Umeno, J., Ashikawa, K., Aoki, M., Matsumoto, T., Nakamura, S., Ninomiya, T., Matsui, T., Hirai, F., Kawaguchi, T., Takazoe, M., Tanaka, H., Motoya, S., Kiyohara, Y., Kitazono, T., Nakamura, Y., Kamatani, N. & Kubo, M., 01-03-2013, In : Inflammatory Bowel Diseases. 19, 3, p. 526-533 8 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Circadian expressions of cardiac ion channel genes in mouse might be associated with the central clock in the SCN but not the peripheral clock in the heart

Tong, M., Watanabe, E., Yamamoto, N., Nagahata-Ishiguro, M., Maemura, K., Takeda, N., Nagai, R. & Ozaki, Y., 01-08-2013, In : Biological Rhythm Research. 44, 4, p. 519-530 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type

Rust, S., Guillard, S., Sachsenmeier, K., Hay, C., Davidson, M., Karlsson, A., Karlsson, R., Brand, E., Lowne, D., Elvin, J., Flynn, M., Kurosawa, G., Hollingsworth, R., Jermutus, L. & Minter, R., 13-02-2013, In : Molecular Cancer. 12, 1, 11.

Research output: Contribution to journalArticle

Open Access
37 Citations (Scopus)

Comparative analysis in cynomolgus macaque identifies a novel human MHC locus controlling platelet blood counts independently of BAK1

Aarnink, A., Garchon, H. J., Okada, Y., Takahashi, A., Matsuda, K., Kubo, M., Nakamura, Y. & Blancher, A., 01-02-2013, In : Journal of Thrombosis and Haemostasis. 11, 2, p. 384-386 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Correction: RNA-binding protein musashi1 modulates glioma cell growth through the post-transcriptional regulation of notch and PI3 kinase/akt signaling pathways (PLoS ONE)

Muto, J., Imai, T., Ogawa, D., Nishimoto, Y., Okada, Y., Mabuchi, Y., Kawase, T., Iwanami, A., Mischel, P. S., Saya, H., Yoshida, K., Matsuzaki, Y. & Okano, H., 25-04-2013, In : PloS one. 8, 4

Research output: Contribution to journalComment/debate

Open Access

Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia

Takao, K., Kobayashi, K., Hagihara, H., Ohira, K., Shoji, H., Hattori, S., Koshimizu, H., Umemori, J., Toyama, K., Nakamura, H. K., Kuroiwa, M., Maeda, J., Atsuzawa, K., Esaki, K., Yamaguchi, S., Furuya, S., Takagi, T., Walton, N. M., Hayashi, N., Suzuki, H. & 7 others, Higuchi, M., Usuda, N., Suhara, T., Nishi, A., Matsumoto, M., Ishii, S. & Miyakawa, T., 01-07-2013, In : Neuropsychopharmacology. 38, 8, p. 1409-1425 17 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)

Effects of exercise after focal cerebral cortex infarction on basal ganglion

Mizutani, K., Sonoda, S., Karasawa, N., Yamada, K., Shimpo, K., Chihara, T., Takeuchi, T., Hasegawa, Y. & Kubo, K. Y., 01-06-2013, In : Neurological Sciences. 34, 6, p. 861-867 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Evaluation of 89Zr-Labeled Human Anti-CD147 Monoclonal Antibody as a Positron Emission Tomography Probe in a Mouse Model of Pancreatic Cancer

Sugyo, A., Tsuji, A. B., Sudo, H., Nagatsu, K., Koizumi, M., Ukai, Y., Kurosawa, G., Zhang, M. R., Kurosawa, Y. & Saga, T., 05-04-2013, In : PloS one. 8, 4, e61230.

Research output: Contribution to journalArticle

Open Access
20 Citations (Scopus)

Exceptionally high conservation of the MHC class I-related gene, MR1, among mammals

Tsukamoto, K., Deakin, J. E., Graves, J. A. M. & Hashimoto, K., 01-02-2013, In : Immunogenetics. 65, 2, p. 115-124 10 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Functional role of CD44v-xCT system in the development of spasmolytic polypeptide-expressing metaplasia

Wada, T., Ishimoto, T., Seishima, R., Tsuchihashi, K., Yoshikawa, M., Oshima, H., Oshima, M., Masuko, T., Wright, N. A., Furuhashi, S., Hirashima, K., Baba, H., Kitagawa, Y., Saya, H. & Nagano, O., 01-10-2013, In : Cancer science. 104, 10, p. 1323-1329 7 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Gene-gene combination effect and interactions among ABCA1, APOA1, SR-B1, and CETP polymorphisms for serum high-density lipoprotein-cholesterol in the japanese population

Nakamura, A., Niimura, H., Kuwabara, K., Takezaki, T., Morita, E., Wakai, K., Hamajima, N., Nishida, Y., Turin, T. C., Suzuki, S., Ohnaka, K., Uemura, H., Ozaki, E., Hosono, S., Mikami, H., Kubo, M. & Tanaka, H., 20-12-2013, In : PloS one. 8, 12, e82046.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema

Pare, G., Kubo, M., Byrd, J. B., McCarty, C. A., Woodard-Grice, A., Teo, K. K., Anand, S. S., Zuvich, R. L., Bradford, Y., Ross, S., Nakamura, Y., Ritchie, M. & Brown, N. J., 01-09-2013, In : Pharmacogenetics and genomics. 23, 9, p. 470-478 9 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Genetic variants associated with warfarin dose in African-American individuals: A genome-wide association study

Perera, M. A., Cavallari, L. H., Limdi, N. A., Gamazon, E. R., Konkashbaev, A., Daneshjou, R., Pluzhnikov, A., Crawford, D. C., Wang, J., Liu, N., Tatonetti, N., Bourgeois, S., Takahashi, H., Bradford, Y., Burkley, B. M., Desnick, R. J., Halperin, J. L., Khalifa, S. I., Langaee, T. Y., Lubitz, S. A. & 22 others, Nutescu, E. A., Oetjens, M., Shahin, M. H., Patel, S. R., Sagreiya, H., Tector, M., Weck, K. E., Rieder, M. J., Scott, S. A., Wu, A. H. B., Burmester, J. K., Wadelius, M., Deloukas, P., Wagner, M. J., Mushiroda, T., Kubo, M., Roden, D. M., Cox, N. J., Altman, R. B., Klein, T. E., Nakamura, Y. & Johnson, J. A., 01-01-2013, In : The Lancet. 382, 9894, p. 790-796 7 p.

Research output: Contribution to journalArticle

155 Citations (Scopus)

Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis

Kou, I., Takahashi, Y., Johnson, T. A., Takahashi, A., Guo, L., Dai, J., Qiu, X., Sharma, S., Takimoto, A., Ogura, Y., Jiang, H., Yan, H., Kono, K., Kawakami, N., Uno, K., Ito, M., Minami, S., Yanagida, H., Taneichi, H., Hosono, N. & 21 others, Tsuji, T., Suzuki, T., Sudo, H., Kotani, T., Yonezawa, I., Londono, D., Gordon, D., Herring, J. A., Watanabe, K., Chiba, K., Kamatani, N., Jiang, Q., Hiraki, Y., Kubo, M., Toyama, Y., Tsunoda, T., Wise, C. A., Qiu, Y., Shukunami, C., Matsumoto, M. & Ikegawa, S., 01-06-2013, In : Nature Genetics. 45, 6, p. 676-679 4 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)

Genome wide analysis of drug-induced torsades de pointes: Lack of common variants with large effect sizes

Behr, E. R., Ritchie, M. D., Tanaka, T., Kääb, S., Crawford, D. C., Nicoletti, P., Floratos, A., Sinner, M. F., Kannankeril, P. J., Wilde, A. A. M., Bezzina, C. R., Schulze-Bahr, E., Zumhagen, S., Guicheney, P., Bishopric, N. H., Marshall, V., Shakir, S., Dalageorgou, C., Bevan, S., Jamshidi, Y. & 14 others, Bastiaenen, R., Myerburg, R. J., Schott, J. J., Camm, A. J., Steinbeck, G., Norris, K., Altman, R. B., Tatonetti, N. P., Jeffery, S., Kubo, M., Nakamura, Y., Shen, Y., George, A. L. & Roden, D. M., 06-11-2013, In : PloS one. 8, 11, e78511.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Genome-wide association analysis of red blood cell traits in African Americans: The cogent network

Chen, Z., Tang, H., Qayyum, R., Schick, U. M., Nalls, M. A., Handsaker, R., Li, J., Lu, Y., Yanek, L. R., Keating, B., Meng, Y., Van Rooij, F. J. A., Okada, Y., Kubo, M., Rasmussen-Torvik, L., Keller, M. F., Lange, L., Evans, M., Bottinger, E. P., Linderman, M. D. & 16 others, Ruderfer, D. M., Hakonarson, H., Papanicolaou, G., Zonderman, A. B., Gottesman, O., Thomson, C., Ziv, E., Singleton, A. B., Loos, R. J. F., Sleiman, P. M. A., Ganesh, S., McCarroll, S., Becker, D. M., Wilson, J. G., Lettre, G. & Reiner, A. P., 01-06-2013, In : Human molecular genetics. 22, 12, p. 2529-2538 10 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Genome Wide Association Study of Age at Menarche in the Japanese Population

Tanikawa, C., Okada, Y., Takahashi, A., Oda, K., Kamatani, N., Kubo, M., Nakamura, Y. & Matsuda, K., 07-05-2013, In : PloS one. 8, 5, e63821.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Genome-Wide Association Study of Breast Cancer in the Japanese Population

Low, S. K., Takahashi, A., Ashikawa, K., Inazawa, J., Miki, Y., Kubo, M., Nakamura, Y. & Katagiri, T., 15-10-2013, In : PloS one. 8, 10, e76463.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan

Low, S. K., Chung, S., Takahashi, A., Zembutsu, H., Mushiroda, T., Kubo, M. & Nakamura, Y., 08-2013, In : Cancer science. 104, 8, p. 1074-1082 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Genome-wide association study of genetic factors related to confectionery intake: Potential roles of the ADIPOQ gene

Wakai, K., Matsuo, K., Matsuda, F., Yamada, R., Takahashi, M., Kawaguchi, T., Yatabe, Y., Ito, H., Hosono, S., Tajima, K., Naito, M., Morita, E., Yin, G., Sakamoto, T., Takashima, N., Suzuki, S., Nakahata, N., Mikami, H., Ohnaka, K., Watanabe, Y. & 4 others, Arisawa, K., Kubo, M., Hamajima, N. & Tanaka, H., 01-11-2013, In : Obesity. 21, 11, p. 2413-2419 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

High-density genotyping study identifies four new susceptibility loci for atopic dermatitis

Ellinghaus, D., Baurecht, H., Esparza-Gordillo, J., Rodríguez, E., Matanovic, A., Marenholz, I., Hübner, N., Schaarschmidt, H., Novak, N., Michel, S., Maintz, L., Werfel, T., Meyer-Hoffert, U., Hotze, M., Prokisch, H., Heim, K., Herder, C., Hirota, T., Tamari, M., Kubo, M. & 29 others, Takahashi, A., Nakamura, Y., Tsoi, L. C., Stuart, P., Elder, J. T., Sun, L., Zuo, X., Yang, S., Zhang, X., Hoffmann, P., Nöthen, M. M., Fölster-Holst, R., Winkelmann, J., Illig, T., Boehm, B. O., Duerr, R. H., Büning, C., Brand, S., Glas, J., McAleer, M. A., Fahy, C. M., Kabesch, M., Brown, S., McLean, W. H. I., Irvine, A. D., Schreiber, S., Lee, Y. A., Franke, A. & Weidinger, S., 01-07-2013, In : Nature Genetics. 45, 7, p. 808-812 5 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: A genome-wide association study

Miki, D., Ochi, H., Takahashi, A., Hayes, C. N., Urabe, Y., Abe, H., Kawaoka, T., Tsuge, M., Hiraga, N., Imamura, M., Kawakami, Y., Aikata, H., Takahashi, S., Akuta, N., Suzuki, F., Ikeda, K., Kumada, H., Karino, Y., Toyota, J., Tsunoda, T. & 4 others, Kubo, M., Kamatani, N., Nakamura, Y. & Chayama, K., 20-12-2013, In : PloS one. 8, 12, e84226.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Identification of a Functional Variant in the MICA Promoter Which Regulates MICA Expression and Increases HCV-Related Hepatocellular Carcinoma Risk

Lo, P. H. Y., Urabe, Y., Kumar, V., Tanikawa, C., Koike, K., Kato, N., Miki, D., Chayama, K., Kubo, M., Nakamura, Y. & Matsuda, K., 11-04-2013, In : PloS one. 8, 4, e61279.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Identification of a Susceptibility Locus for Severe Adolescent Idiopathic Scoliosis on Chromosome 17q24.3

Miyake, A., Kou, I., Takahashi, Y., Johnson, T. A., Ogura, Y., Dai, J., Qiu, X., Takahashi, A., Jiang, H., Yan, H., Kono, K., Kawakami, N., Uno, K., Ito, M., Minami, S., Yanagida, H., Taneichi, H., Hosono, N., Tsuji, T., Suzuki, T. & 11 others, Sudo, H., Kotani, T., Yonezawa, I., Kubo, M., Tsunoda, T., Watanabe, K., Chiba, K., Toyama, Y., Qiu, Y., Matsumoto, M. & Ikegawa, S., 04-09-2013, In : PloS one. 8, 9, e72802.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis

Asano, K., Matsumoto, T., Umeno, J., Hirano, A., Esaki, M., Hosono, N., Matsui, T., Kiyohara, Y., Nakamura, Y., Kubo, M. & Kitazono, T., 01-09-2013, In : Inflammatory Bowel Diseases. 19, 10, p. 2061-2068 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Impact of four loci on serum tamsulosin hydrochloride concentration

Takata, R., Matsuda, K., Sugimura, J., Obara, W., Fujioka, T., Okihara, K., Takaha, N., Miki, T., Ashida, S., Inoue, K., Tanikawa, C., Shuin, T., Sasaki, S., Kojima, Y., Kohri, K., Kubo, M., Yamaguchi, M., Ohnishi, Y. & Nakamura, Y., 01-01-2013, In : Journal of Human Genetics. 58, 1, p. 21-26 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia

Yee, S. W., Mefford, J. A., Singh, N., Percival, M. E., Stecula, A., Yang, K., Witte, J. S., Takahashi, A., Kubo, M., Matsuda, K., Giacomini, K. M. & Andreadis, C., 01-06-2013, In : Journal of Human Genetics. 58, 6, p. 353-361 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Impact of PSCA Variation on Gastric Ulcer Susceptibility

Tanikawa, C., Matsuo, K., Kubo, M., Takahashi, A., Ito, H., Tanaka, H., Yatabe, Y., Yamao, K., Kamatani, N., Tajima, K., Nakamura, Y. & Matsuda, K., 21-05-2013, In : PloS one. 8, 5, e63698.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of paclitaxel-induced sensory peripheral neuropathy

Wheeler, H. E., Gamazon, E. R., Wing, C., Njiaju, U. O., Njoku, C., Baldwin, R. M., Owzar, K., Jiang, C., Watson, D., Shterev, I., Kubo, M., Zembutsu, H., Winer, E. P., Hudis, C. A., Shulman, L. N., Nakamura, Y., Ratain, M. J., Kroetz, D. L., Cox, N. J. & Dolan, M. E., 15-01-2013, In : Clinical Cancer Research. 19, 2, p. 491-499 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene

Himes, B. E., Sheppard, K., Berndt, A., Leme, A. S., Myers, R. A., Gignoux, C. R., Levin, A. M., Gauderman, W. J., Yang, J. J., Mathias, R. A., Romieu, I., Torgerson, D. G., Roth, L. A., Huntsman, S., Eng, C., Klanderman, B., Ziniti, J., Senter-Sylvia, J., Szefler, S. J., Lemanske, R. F. & 35 others, Zeiger, R. S., Strunk, R. C., Martinez, F. D., Boushey, H., Chinchilli, V. M., Israel, E., Mauger, D., Koppelman, G. H., Postma, D. S., Nieuwenhuis, M. A. E., Vonk, J. M., Lima, J. J., Irvin, C. G., Peters, S. P., Kubo, M., Tamari, M., Nakamura, Y., Litonjua, A. A., Tantisira, K. G., Raby, B. A., Bleecker, E. R., Meyers, D. A., London, S. J., Barnes, K. C., Gilliland, F. D., Williams, L. K., Burchard, E. G., Nicolae, D. L., Ober, C., DeMeo, D. L., Silverman, E. K., Paigen, B., Churchill, G., Shapiro, S. D. & Weiss, S. T., 14-02-2013, In : PloS one. 8, 2, e56179.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant

Song, Y. Q., Karasugi, T., Cheung, K. M. C., Chiba, K., Ho, D. W. H., Miyake, A., Kao, P. Y. P., Sze, K. L., Yee, A., Takahashi, A., Kawaguchi, Y., Mikami, Y., Matsumoto, M., Togawa, D., Kanayama, M., Shi, D., Dai, J., Jiang, Q., Wu, C., Tian, W. & 24 others, Wang, N., Leong, J. C. Y., Luk, K. D. K., Yip, S. P., Cherny, S. S., Wang, J., Mundlos, S., Kelempisioti, A., Eskola, P. J., Männikkö, M., Mäkelä, P., Karppinen, J., Järvelin, M. R., O'Reilly, P. F., Kubo, M., Kimura, T., Kubo, T., Toyama, Y., Mizuta, H., Cheah, K. S. E., Tsunoda, T., Sham, P. C., Ikegawa, S. & Chan, D., 01-11-2013, In : Journal of Clinical Investigation. 123, 11, p. 4909-4917 9 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

MTHFR, MTR and MTRR polymorphisms and risk of chronic kidney disease in Japanese: Cross-sectional data from the J-MICC Study

Hishida, A., Okada, R., Guang, Y., Naito, M., Wakai, K., Hosono, S., Nakamura, K., Turin, T. C., Suzuki, S., Niimura, H., Mikami, H., Otonari, J., Kuriyama, N., Katsuura, S., Kubo, M., Tanaka, H. & Hamajima, N., 01-12-2013, In : International Urology and Nephrology. 45, 6, p. 1613-1620 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Neuronal per arnt sim (PAS) domain protein 4 (NPAS4) regulates neurite outgrowth and phosphorylation of synapsin i

Yun, J., Nagai, T., Furukawa-Hibi, Y., Kuroda, K., Kaibuchi, K., Greenberg, M. E. & Yamada, K., 25-01-2013, In : Journal of Biological Chemistry. 288, 4, p. 2655-2664 10 p.

Research output: Contribution to journalArticle

Open Access
20 Citations (Scopus)

Nobiletin, a citrus flavonoid, ameliorates cognitive impairment, oxidative burden, and hyperphosphorylation of tau in senescence-accelerated mouse

Nakajima, A., Aoyama, Y., Nguyen, T. T. L., Shin, E. J., Kim, H. C., Yamada, S., Nakai, T., Nagai, T., Yokosuka, A., Mimaki, Y., Ohizumi, Y. & Yamada, K., 01-08-2013, In : Behavioural Brain Research. 250, p. 351-360 10 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Osteogenic Differentiation Capacity of Human Skeletal Muscle-Derived Progenitor Cells

Oishi, T., Uezumi, A., Kanaji, A., Yamamoto, N., Yamaguchi, A., Yamada, H. & Tsuchida, K., 14-02-2013, In : PloS one. 8, 2, e56641.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Pathway analysis of genome-wide data improves warfarin dose prediction.

Daneshjou, R., Tatonetti, N. P., Karczewski, K. J., Sagreiya, H., Bourgeois, S., Drozda, K., Burmester, J. K., Tsunoda, T., Nakamura, Y., Kubo, M., Tector, M., Limdi, N. A., Cavallari, L. H., Perera, M., Johnson, J. A., Klein, T. E. & Altman, R. B., 2013, In : Unknown Journal. 14 Suppl 3

Research output: Contribution to journalArticle

12 Citations (Scopus)

Pelvic axis-based gait analysis for ataxic mice

Takayanagi, N., Beppu, H., Mizutani, K., Tomita, Y., Nagao, S., Suzuki, S., Orand, A., Takahashi, H. & Sonoda, S., 28-08-2013, In : Journal of Neuroscience Methods. 219, 1, p. 162-168 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: Genome-wide associations and functional genomics

Ji, Y., Biernacka, J. M., Hebbring, S., Chai, Y., Jenkins, G. D., Batzler, A., Snyder, K. A., Drews, M. S., Desta, Z., Flockhart, D., Mushiroda, T., Kubo, M., Nakamura, Y., Kamatani, N., Schaid, D., Weinshilboum, R. M. & Mrazek, D. A., 01-10-2013, In : Pharmacogenomics Journal. 13, 5, p. 456-463 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

PLD4 as a novel susceptibility gene for systemic sclerosis in a Japanese population

Terao, C., Ohmura, K., Kawaguchi, Y., Nishimoto, T., Kawasaki, A., Takehara, K., Furukawa, H., Kochi, Y., Ota, Y., Ikari, K., Sato, S., Tohma, S., Yamada, R., Yamamoto, K., Kubo, M., Yamanaka, H., Kuwana, M., Tsuchiya, N., Matsuda, F. & Mimori, T., 01-02-2013, In : Arthritis and Rheumatism. 65, 2, p. 472-480 9 p.

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38 Citations (Scopus)

Polymorphisms in genes encoding antioxidant enzymes (SOD2, CAT, GPx, TXNRD, SEPP1, SEP15 and SELS) and risk of chronic kidney disease in Japanese - Cross-sectional data from the J-MICC study

Hishida, A., Okada, R., Naito, M., Morita, E., Wakai, K., Hamajima, N., Hosono, S., Nanri, H., Turin, T. C., Suzuki, S., Kuwabara, K., Mikami, H., Budhathoki, S., Watanabe, I., Arisawa, K., Kubo, M. & Tanaka, H., 01-08-2013, In : Journal of Clinical Biochemistry and Nutrition. 53, 1, p. 15-20 6 p.

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7 Citations (Scopus)

Polymorphisms in PPAR genes (PPARD, PPARG, and PPARGC1A) and the risk of chronic kidney disease in Japanese: Cross-sectional data from the J-MICC study

Hishida, A., Wakai, K., Naito, M., Tamura, T., Kawai, S., Hamajima, N., Oze, I., Imaizumi, T., Turin, T. C., Suzuki, S., Kheradmand, M., Mikami, H., Ohnaka, K., Watanabe, Y., Arisawa, K., Kubo, M. & Tanaka, H., 06-12-2013, In : PPAR Research. 980471.

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3 Citations (Scopus)

Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: Individualized breast cancer prevention

Ingle, J. N., Liu, M., Lawrence Wickerham, D., Schaid, D. J., Wang, L., Mushiroda, T., Kubo, M., Costantino, J. P., Vogel, V. G., Paik, S., Goetz, M. P., Ames, M. M., Jenkins, G. D., Batzler, A., Carlson, E. E., Flockhart, D. A., Wolmark, N., Nakamura, Y. & Weinshilboum, R. M., 01-07-2013, In : Cancer Discovery. 3, 7, p. 812-825 14 p.

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36 Citations (Scopus)

Seven new loci associated with age-related macular degeneration

Fritsche, L. G., Chen, W., Schu, M., Yaspan, B. L., Yu, Y., Thorleifsson, G., Zack, D. J., Arakawa, S., Cipriani, V., Ripke, S., Igo, R. P., Buitendijk, G. H. S., Sim, X., Weeks, D. E., Guymer, R. H., Merriam, J. E., Francis, P. J., Hannum, G., Agarwal, A., Armbrecht, A. M. & 136 others, Audo, I., Aung, T., Barile, G. R., Benchaboune, M., Bird, A. C., Bishop, P. N., Branham, K. E., Brooks, M., Brucker, A. J., Cade, W. H., Cain, M. S., Campochiaro, P. A., Chan, C. C., Cheng, C. Y., Chew, E. Y., Chin, K. A., Chowers, I., Clayton, D. G., Cojocaru, R., Conley, Y. P., Cornes, B. K., Daly, M. J., Dhillon, B., Edwards, A. O., Evangelou, E., Fagerness, J., Ferreyra, H. A., Friedman, J. S., Geirsdottir, A., George, R. J., Gieger, C., Gupta, N., Hagstrom, S. A., Harding, S. P., Haritoglou, C., Heckenlively, J. R., Holz, F. G., Hughes, G., Ioannidis, J. P. A., Ishibashi, T., Joseph, P., Jun, G., Kamatani, Y., Katsanis, N., N Keilhauer, C., Khan, J. C., Kim, I. K., Kiyohara, Y., Klein, B. E. K., Klein, R., Kovach, J. L., Kozak, I., Lee, C. J., Lee, K. E., Lichtner, P., Lotery, A. J., Meitinger, T., Mitchell, P., Mohand-Saïd, S., Moore, A. T., Morgan, D. J., Morrison, M. A., Myers, C. E., Naj, A. C., Nakamura, Y., Okada, Y., Orlin, A., Ortube, M. C., Othman, M. I., Pappas, C., Park, K. H., Pauer, G. J. T., Peachey, N. S., Poch, O., Priya, R. R., Reynolds, R., Richardson, A. J., Ripp, R., Rudolph, G., Ryu, E., Sahel, J. A., Schaumberg, D. A., Scholl, H. P. N., Schwartz, S. G., Scott, W. K., Shahid, H., Sigurdsson, H., Silvestri, G., Sivakumaran, T. A., Smith, R. T., Sobrin, L., Souied, E. H., Stambolian, D. E., Stefansson, H., Sturgill-Short, G. M., Takahashi, A., Tosakulwong, N., Truitt, B. J., Tsironi, E. E., Uitterlinden, A. G., Van Duijn, C. M., Vijaya, L., Vingerling, J. R., Vithana, E. N., Webster, A. R., Wichmann, H. E., Winkler, T. W., Wong, T. Y., Wright, A. F., Zelenika, D., Zhang, M., Zhao, L., Zhang, K., Klein, M. L., Hageman, G. S., Lathrop, G. M., Stefansson, K., Allikmets, R., Baird, P. N., Gorin, M. B., Wang, J. J., Klaver, C. C. W., Seddon, J. M., Pericak-Vance, M. A., Iyengar, S. K., Yates, J. R. W., Swaroop, A., Weber, B. H. F., Kubo, M., Deangelis, M. M., Léveillard, T., Thorsteinsdottir, U., Haines, J. L., Farrer, L. A., Heid, I. M. & Abecasis, G. R., 01-04-2013, In : Nature Genetics. 45, 4, p. 433-439 7 p.

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482 Citations (Scopus)