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2006

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S. I., Tahara, H., Nakayama, K., Nakayama, K. I., Ide, T., Saya, H. & Hara, E., 01-11-2006, In : Nature Cell Biology. 8, 11, p. 1291-1297 7 p.

Research output: Contribution to journalArticle

313 Citations (Scopus)

Organization and structure of hox gene loci in medaka genome and comparison with those of pufferfish and zebrafish genomes

Kurosawa, G., Takamatsu, N., Takahashi, M., Sumitomo, M., Sanaka, E., Yamada, K., Nishii, K., Matsuda, M., Asakawa, S., Ishiguro, H., Miura, K., Kurosawa, Y., Shimizu, N., Kohara, Y. & Hori, H., 29-03-2006, In : Gene. 370, 1-2, p. 75-82 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Osteopontin participates in Th1-mediated host resistance against nonlethal malaria parasite Plasmodium chabaudi chabaudi infection in mice

Maeno, Y., Nakazawa, S., Yamamoto, N., Shinzato, M., Nagashima, S., Tanaka, K., Sasaki, J., Rittling, S. R., Denhardt, D. T., Uede, T. & Taniguchi, K., 01-04-2006, In : Infection and Immunity. 74, 4, p. 2423-2427 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1/2 activation in the prefrontal cortex of mice

Kamei, H., Nagai, T., Nakano, H., Togan, Y., Takayanagi, M., Takahashi, K., Kobayashi, K., Yoshida, S., Maeda, K., Takuma, K., Nabeshima, T. & Yamada, K., 01-01-2006, In : Biological Psychiatry. 59, 1, p. 75-84 10 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)

Studies of the role of steroid hormone in the regulation of oocyte maturation in cattle

Wang, H. F., Isobe, N., Kumamoto, K., Yamashiro, H., Yamashita, Y. & Terada, T., 03-02-2006, In : Reproductive Biology and Endocrinology. 4, 4.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Suppression of centrosome amplification after DNA damage depends on p27 accumulation

Sugihara, E., Kanai, M., Saito, S., Nitta, T., Toyoshima, H., Nakayama, K., Nakayama, K. I., Fukasawa, K., Schwab, M., Saya, H. & Miwa, M., 15-04-2006, In : Cancer Research. 66, 8, p. 4020-4029 10 p.

Research output: Contribution to journalArticle

Open Access
33 Citations (Scopus)

Suppressor of cytokine signalling 1 in lymphocytes regulates the development of intestinal inflammation in mice

Inagaki-Ohara, K., Sasaki, A., Matsuzaki, G., Ikeda, T., Hotokezaka, M., Chijiiwa, K., Kubo, M., Yoshida, H., Nawa, Y. & Yoshimura, A., 01-02-2006, In : Gut. 55, 2, p. 212-219 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

The effect of fexofenadine on pruritus in a mouse model (HR-ADf) of atopic dermatitis

Akamatsu, H., Makiura, M., Yamamoto, N., Yagami, A., Shimizu, Y. & Matsunaga, K., 01-01-2006, In : Journal of International Medical Research. 34, 5, p. 495-504 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The influence of current and former smoking on gingival bleeding: The hisayama study

Shimazaki, Y., Saito, T., Kiyohara, Y., Kato, I., Kubo, M., Iida, M. & Yamashita, Y., 01-08-2006, In : Journal of Periodontology. 77, 8, p. 1430-1435 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

The serum pepsinogen test as a predictor of gastric cancer: The Hisayama study

Oishi, Y., Kiyohara, Y., Kubo, M., Tanaka, K., Tanizaki, Y., Ninomiya, T., Doi, Y., Shikata, K., Yonemoto, K., Shirota, T., Matsumoto, T. & Iida, M., 01-04-2006, In : American Journal of Epidemiology. 163, 7, p. 629-637 9 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)
2005

Androgen receptor pathway in rats with autosomal dominant polycystic kidney disease

Nagao, S., Kusaka, M., Nishii, K., Marunouchi, T., Kurahashi, H., Takahashi, H. & Grantham, J., 09-12-2005, In : Journal of the American Society of Nephrology. 16, 7, p. 2052-2062 11 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Chronic kidney disease and cardiovascular disease in a general Japanese population: The Hisayama Study

Ninomiya, T., Kiyohara, Y., Kubo, M., Tanizaki, Y., Doi, Y., Okubo, K., Wakugawa, Y., Hata, J., Oishi, Y., Shikata, K., Yonemoto, K., Hirakata, H. & Iida, M., 01-07-2005, In : Kidney International. 68, 1, p. 228-236 9 p.

Research output: Contribution to journalArticle

296 Citations (Scopus)

Concentration of transforming growth factor β2 in aqueous humor

Yamamoto, N., Itonaga, K., Marunouchi, T. & Majima, K., 25-05-2005, In : Ophthalmic Research. 37, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Contribution of Vα24+Vβ11+ natural killer T cells in Wilsonian hepatitis

Kinebuchi, M., Matsuura, A., Ohya, K., Abo, W. & Kitazawa, J., 01-01-2005, In : Clinical and Experimental Immunology. 139, 1, p. 144-151 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Effects of memantine and donepezil on amyloid β-induced memory impairment in a delayed-matching to position task in rats

Yamada, K., Takayanagi, M., Kamei, H., Nagai, T., Dohniwa, M., Kobayashi, K., Yoshida, S., Ohhara, T., Takauma, K. & Nabeshima, T., 30-07-2005, In : Behavioural Brain Research. 162, 2, p. 191-199 9 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Elevated C-reactive protein is a predictor of the development of diabetes in a general Japanese population: The Hisayama study

Doi, Y., Kiyohara, Y., Kubo, M., Ninomiya, T., Wakugawa, Y., Yonemoto, K., Iwase, M. & Iida, M., 01-10-2005, In : Diabetes care. 28, 10, p. 2497-2500 4 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion

Sato, Y., Araki, H., Kato, J., Nakamura, K., Kawano, Y., Kobune, M., Sato, T., Miyanishi, K., Takayama, T., Takahashi, M., Takimoto, R., Iyama, S., Matsunaga, T., Ohtani, S., Matsuura, A., Hamada, H. & Niitsu, Y., 15-07-2005, In : Blood. 106, 2, p. 756-763 8 p.

Research output: Contribution to journalArticle

521 Citations (Scopus)

Impact of fasting plasma glucose levels on gastric cancer incidence in a general Japanese population: The Hisayama study

Yamagata, H., Kiyohara, Y., Nakamura, S., Kubo, M., Tanizaki, Y., Matsumoto, T., Tanaka, K., Kato, I., Shirota, T. & Iida, M., 01-04-2005, In : Diabetes care. 28, 4, p. 789-794 6 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Molecular mechanism of tumorigenesis by cell cycle regulation and new therapeutical approaches

Saya, H., 06-2005, In : Japanese Journal of Neurosurgery. 14, 6, p. 373-378 6 p.

Research output: Contribution to journalArticle

Open Access

Observation of the intracellular behavior of recombinant Yersinia pseudotuberculosis invasin protein

Koga, H., Izawa, I., Araki, N., Saya, H. & Mimori, T., 01-01-2005, In : MICROBIOLOGY and IMMUNOLOGY. 49, 4, p. 297-302 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Over-expression of Aurora-A targets cytoplasmic polyadenylation element binding protein and promotes mRNA polyadenylation of Cdk1 and cyclin B1

Sasayama, T., Marumoto, T., Kunitoku, N., Zhang, D., Tamaki, N., Kohmura, E., Saya, H. & Hirota, T., 01-07-2005, In : Genes to Cells. 10, 7, p. 627-638 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Relationship between C-reactive protein and glucose levels in community-dwelling subjects without diabetes: The Hisayama study

Doi, Y., Kiyohara, Y., Kubo, M., Tanizaki, Y., Okubo, K., Ninomiya, T., Iwase, M. & Iida, M., 01-05-2005, In : Diabetes care. 28, 5, p. 1211-1213 3 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Relationship between drinking and periodontitis: The Hisayama study

Shimazaki, Y., Saito, T., Kiyohara, Y., Kato, I., Kubo, M., Iida, M. & Yamashita, Y., 01-09-2005, In : Journal of Periodontology. 76, 9, p. 1534-1541 8 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

RNA interference targeting aurora kinase A suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells

Hata, T., Furukawa, T., Sunamura, M., Egawa, S., Motoi, F., Ohmura, N., Marumoto, T., Saya, H. & Horii, A., 01-04-2005, In : Cancer Research. 65, 7, p. 2899-2905 7 p.

Research output: Contribution to journalArticle

Open Access
192 Citations (Scopus)

Secular trends in the incidence, mortality, and survival rate of gastric cancer in a general Japanese population: The Hisayama study

Tanaka, K., Kiyohara, Y., Kubo, M., Matsumoto, T., Tanizaki, Y., Okubo, K., Ninomiya, T., Oishi, Y., Shikata, K. & Iida, M., 01-06-2005, In : Cancer Causes and Control. 16, 5, p. 573-578 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Suppressed expression of GTP cyclohydrolase I mRNA and accelerated expression of inducible nitric oxide synthase mRNA in endomyocardial biopsy specimens from patients with dilated cardiomyopathy

Ohtsuki, M., Nomura, T., Morimoto, S. I., Hiramitsu, S., Uemura, A., Kato, S., Kato, Y., Shiraishi, H., Shimokubo, J., Yamamoto, N. & Hishida, H., 03-2005, In : Clinica Chimica Acta. 353, 1-2, p. 103-107 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Ten year recurrence after first ever stroke in a Japanese community: The Hisayama study

Hata, J., Tanizaki, Y., Kiyohara, Y., Kato, I., Kubo, M., Tanaka, K., Okubo, K., Nakamura, H., Oishi, Y., Ibayashi, S. & Iida, M., 01-03-2005, In : Journal of Neurology, Neurosurgery and Psychiatry. 76, 3, p. 368-372 5 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin filament dynamics via the Rho-ROCK-LIMK2-cofilin pathway

Ozawa, T., Araki, N., Yunoue, S., Tokuo, H., Feng, L., Patrakitkomjorn, S., Hara, T., Ichikawa, Y., Matsumoto, K., Fuji, K. & Saya, H., 25-11-2005, In : Journal of Biological Chemistry. 280, 47, p. 39524-39533 10 p.

Research output: Contribution to journalArticle

Open Access
51 Citations (Scopus)

The prevalence of pseudoexfoliation syndrome in a Japanese population: The hisayama study

Miyazaki, M., Kubota, T., Kubo, M., Kiyohara, Y., Iida, M., Nose, Y. & Ishibashi, T., 01-12-2005, In : Journal of Glaucoma. 14, 6, p. 482-484 3 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

The tumor suppressor WARTS activates the Omi/HtrA2-dependent pathway of cell death

Kuninaka, S., Nomura, M., Hirota, T., Iida, S. I., Hara, T., Honda, S., Kunitoku, N., Sasayama, T., Arima, Y., Marumoto, T., Koja, K., Yonehara, S. & Saya, H., 11-08-2005, In : Oncogene. 24, 34, p. 5287-5298 12 p.

Research output: Contribution to journalArticle

Open Access
39 Citations (Scopus)

Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria

Arima, Y., Nitta, M., Kuninaka, S., Zhang, D., Fujiwara, T., Taya, Y., Nakao, M. & Saya, H., 13-05-2005, In : Journal of Biological Chemistry. 280, 19, p. 19166-19176 11 p.

Research output: Contribution to journalArticle

Open Access
116 Citations (Scopus)

Triamcinolone-assisted internal limiting membrane peeling during idiopathic macular hole surgery

Horio, N., Horiguchi, M. & Yamamoto, N., 01-01-2005, In : Archives of Ophthalmology. 123, 1, p. 96-99 4 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2004

Activation of m-Calpain Is Required for Chromosome Alignment on the Metaphase Plate during Mitosis

Honda, S., Marumoto, T., Hirota, T., Nitta, M., Arima, Y., Ogawa, M. & Saya, H., 12-03-2004, In : Journal of Biological Chemistry. 279, 11, p. 10615-10623 9 p.

Research output: Contribution to journalArticle

Open Access
35 Citations (Scopus)

Behavioural adaptations to addictive drugs in mice lacking the NMDA receptor ε1 subunit

Miyamoto, Y., Yamada, K., Nagai, T., Mori, H., Mishina, M., Furukawa, H., Noda, Y. & Nabeshima, T., 01-01-2004, In : European Journal of Neuroscience. 19, 1, p. 151-158 8 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Cell-matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca2+ influx and PKC activation

Nagano, O., Murakami, D., Hartmann, D., De Strooper, B., Saftig, P., Iwatsubo, T., Nakajima, M., Shinohara, M. & Saya, H., 21-06-2004, In : Journal of Cell Biology. 165, 6, p. 893-902 10 p.

Research output: Contribution to journalArticle

Open Access
206 Citations (Scopus)

Comparison of diagnostic methods for diabetes mellitus based on prevalence of retinopathy in a Japanese population: The Hisayama study

Miyazaki, M., Kubo, M., Kiyohara, Y., Okubo, K., Nakamura, H., Fujisawa, K., Hata, Y., Tokunaga, S., Iida, M., Nose, Y. & Ishibashi, T., 01-08-2004, In : Diabetologia. 47, 8, p. 1411-1415 5 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Concentration of transforming growth factor-β2 in the aqueous humor

Majima, K., Yamamoto, N., Itonaga, K., Kiribuchi, K., Inuzuka, H. & Haki, K., 09-02-2004, In : Japanese Journal of Clinical Ophthalmology. 58, 1, p. 61-64 4 p.

Research output: Contribution to journalArticle

Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models

Zhang, D., Hirota, T., Marumoto, T., Shimizu, M., Kunitoku, N., Sasayama, T., Arima, Y., Feng, L., Suzuki, M., Takeya, M. & Saya, H., 18-11-2004, In : Oncogene. 23, 54, p. 8720-8730 11 p.

Research output: Contribution to journalArticle

Open Access
121 Citations (Scopus)

Dependence of Paclitaxel Sensitivity on a Functional Spindle Assembly Checkpoint

Sudo, T., Nitta, M., Saya, H. & Ueno, N. T., 01-04-2004, In : Cancer Research. 64, 7, p. 2502-2508 7 p.

Research output: Contribution to journalArticle

Open Access
209 Citations (Scopus)

Dialysis-related hypotension as a cause of progressive frontal lobe atrophy in chronic hemodialysis patients: A 3-year prospective study

Mizumasa, T., Hirakata, H., Yoshimitsu, T., Hirakata, E., Kubo, M., Kashiwagi, M., Tanaka, H., Kanai, H., Fujimi, S. & Iida, M., 15-06-2004, In : Nephron - Clinical Practice. 97, 1, p. c23-c30

Research output: Contribution to journalArticle

60 Citations (Scopus)

Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition

Arima, Y., Hirota, T., Bronner, C., Mousli, M., Fujiwara, T., Niwa, S. I., Ishikawa, H. & Saya, H., 01-02-2004, In : Genes to Cells. 9, 2, p. 131-142 12 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)

Expression of foreign proteins in Escherichia coli by fusing with an archaeal FK506 binding protein

Ideno, A., Furutani, M., Iwabuchi, T., Iida, T., Iba, Y., Kurosawa, Y., Sakuraba, H., Ohshima, T., Kawarabayashi, Y. & Maruyama, T., 01-03-2004, In : Applied Microbiology and Biotechnology. 64, 1, p. 99-105 7 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Hemolytic crisis with fulminant hepatic failure in Wilson disease without consanguinity

Kitazawa, J., Kaizuka, M., Kasai, M., Noda, Y., Takahashi, Y., Terui, K., Narumi, S., Hakamada, K., Sasaki, M., Kamata, Y., Endo, T., Nomachi, S., Saikai, T., Mizoguchi, Y., Kinebuchi, M., Ito, E. & Matsuura, A., 01-12-2004, In : Pediatrics International. 46, 6, p. 726-729 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Hyperhomocysteinemia and the development of chronic kidney disease in a general population: The Hisayama study

Ninomiya, T., Kiyohara, Y., Kubo, M., Tanizaki, Y., Tanaka, K., Okubo, K., Nakamura, H., Hata, J., Oishi, Y., Kato, I., Hirakata, H. & Iida, M., 01-09-2004, In : American Journal of Kidney Diseases. 44, 3, p. 437-445 9 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Incidence and prognosis of gastric cancer in a population-based cohort survey: The Hisayama study

Tanaka, K., Kiyohara, Y., Kato, I., Matsumoto, T., Yamagata, H., Kubo, M., Tanizaki, Y., Okuho, K., Nakamura, H., Iwamoto, H., Nakayama, K. & Iida, M., 01-05-2004, In : Scandinavian Journal of Gastroenterology. 39, 5, p. 459-463 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Influence of edge shape and surface property of intraocular lens on the physiological activity of cultured lens epithelial cells

Majima, K., Yamamoto, N. & Itonaga, K., 02-07-2004, In : Japanese Journal of Clinical Ophthalmology. 58, 5, p. 835-839 5 p.

Research output: Contribution to journalArticle

Isolation of Human Monoclonal Antibodies That Neutralize Human Rotavirus

Higo-Moriguchi, K., Akahori, Y., Iba, Y., Kurosawa, Y. & Taniguchi, K., 01-04-2004, In : Journal of Virology. 78, 7, p. 3325-3332 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Mechanism and biological significance of sequential cleavages of CD44 - A potential molecular target for cancer therapy

Nagano, O., Murakami, D. & Saya, H., 01-09-2004, In : Biotherapy. 18, 5, p. 405-411 7 p.

Research output: Contribution to journalArticle

PKA phosphorylation and 14-3-3 interaction regulate the function of neurofibromatosis type I tumor suppressor, neurofibromin

Feng, L., Yunoue, S., Tokuo, H., Ozawa, T., Zhang, D., Patrakitkomjorn, S., Ichimura, T., Saya, H. & Araki, N., 16-01-2004, In : FEBS Letters. 557, 1-3, p. 275-282 8 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
8 Citations (Scopus)