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2018

Blood lipid-related low-frequency variants in LDLR and PCSK9 are associated with onset age and risk of myocardial infarction in Japanese

Tajima, T., Morita, H., Ito, K., Yamazaki, T., Kubo, M., Komuro, I. & Momozawa, Y., 01-12-2018, In : Scientific reports. 8, 1, 8107.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Characterization of a G10P[14] rotavirus strain from a diarrheic child in Thailand: Evidence for bovine-to-human zoonotic transmission

Tacharoenmuang, R., Komoto, S., Guntapong, R., Ide, T., Singchai, P., Upachai, S., Fukuda, S., Yoshida, Y., Murata, T., Yoshikawa, T., Ruchusatsawat, K., Motomura, K., Takeda, N., Sangkitporn, S. & Taniguchi, K., 01-09-2018, In : Infection, Genetics and Evolution. 63, p. 43-57 15 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Characterization of unusual DS-1-like G3P[8] rotavirus strains in children with diarrhea in Japan

Komoto, S., Ide, T., Negoro, M., Tanaka, T., Asada, K., Umemoto, M., Kuroki, H., Ito, H., Tanaka, S., Ito, M., Fukuda, S., Suga, S., Kamiya, H., Nakano, T. & Taniguchi, K., 05-2018, In : Journal of Medical Virology. 90, 5, p. 890-898 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility

Tanikawa, C., Ueda, K., Suzuki, A., Iida, A., Nakamura, R., Atsuta, N., Tohnai, G., Sobue, G., Saichi, N., Momozawa, Y., Kamatani, Y., Kubo, M., Yamamoto, K., Nakamura, Y. & Matsuda, K., 06-02-2018, In : Cell Reports. 22, 6, p. 1473-1483 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Corticotropin-releasing hormone-binding protein is up-regulated by brain-derived neurotrophic factor and is secreted in an activity-dependent manner in rat cerebral cortical neurons

Adachi, N., Suzuki, S., Matsuoka, H., Fushimi, S., Ono, J., Ohta, K. I., Hirai, Y., Miki, T. & Koshimizu, H., 07-2018, In : Journal of neurochemistry. 146, 1, p. 99-110 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Decrease in PSCA expression caused by Helicobacter pylori infection may promote progression to severe gastritis

Toyoshima, O., Tanikawa, C., Yamamoto, R., Watanabe, H., Yamashita, H., Sakitani, K., Yoshida, S., Kubo, M., Matsuo, K., Ito, H., Koike, K., Seto, Y. & Matsuda, K., 01-01-2018, In : Oncotarget. 9, 3, p. 3936-3945 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese

Okada, Y., Momozawa, Y., Sakaue, S., Kanai, M., Ishigaki, K., Akiyama, M., Kishikawa, T., Arai, Y., Sasaki, T., Kosaki, K., Suematsu, M., Matsuda, K., Yamamoto, K., Kubo, M., Hirose, N. & Kamatani, Y., 01-12-2018, In : Nature Communications. 9, 1, 1631.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Development of a functional thyroid model based on an organoid culture system

Saito, Y., Onishi, N., Takami, H., Seishima, R., Inoue, H., Hirata, Y., Kameyama, K., Tsuchihashi, K., Sugihara, E., Uchino, S., Ito, K., Kawakubo, H., Takeuchi, H., Kitagawa, Y., Saya, H. & Nagano, O., 04-03-2018, In : Biochemical and Biophysical Research Communications. 497, 2, p. 783-789 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Development of a highly sensitive device for counting the number of disease-specific exosomes in human sera

Kabe, Y., Suematsu, M., Sakamoto, S., Hirai, M., Koike, I., Hishiki, T., Matsuda, A., Hasegawa, Y., Tsujita, K., Ono, M., Minegishi, N., Hozawa, A., Murakami, Y., Kubo, M., Itonaga, M. & Handa, H., 10-2018, In : Clinical Chemistry. 64, 10, p. 1463-1473 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Efficacy evaluation of combination treatment using gemcitabine and radioimmunotherapy with90 y-labeled fully human anti-CD147 monoclonal antibody 059-053 in a BxPC-3 xenograft mouse model of refractory pancreatic cancer

Sugyo, A., Tsuji, A. B., Sudo, H., Koizumi, M., Ukai, Y., Kurosawa, G., Kurosawa, Y., Saga, T. & Higashi, T., 10-2018, In : International journal of molecular sciences. 19, 10, 2979.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Elucidating the genetic architecture of reproductive ageing in the Japanese population

Horikoshi, M., Day, F. R., Akiyama, M., Hirata, M., Kamatani, Y., Matsuda, K., Ishigaki, K., Kanai, M., Wright, H., Toro, C. A., Ojeda, S. R., Lomniczi, A., Kubo, M., Ong, K. K. & Perry, J. R. B., 01-12-2018, In : Nature Communications. 9, 1, 1977.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Extracellular proteoglycan decorin maintains human hair follicle stem cells

Miyachi, K., Yamada, T., Kawagishi-Hotta, M., Hasebe, Y., Date, Y., Hasegawa, S., Arima, M., Iwata, Y., Kobayashi, T., Numata, S., Yamamoto, N., Nakata, S., Sugiura, K. & Akamatsu, H., 12-2018, In : Journal of Dermatology. 45, 12, p. 1403-1410 8 p.

Research output: Contribution to journalArticle

Fc-gamma receptor polymorphisms, cetuximab therapy, and overall survival in the CCTG CO.20 trial of metastatic colorectal cancer

Shepshelovich, D., Townsend, A. R., Espin-Garcia, O., Latifovic, L., O’Callaghan, C. J., Jonker, D. J., Tu, D., Chen, E., Morgen, E., Price, T. J., Shapiro, J., Siu, L. L., Kubo, M., Dobrovic, A., Ratain, M. J., Xu, W., Mushiroda, T. & Liu, G., 11-2018, In : Cancer Medicine. 7, 11, p. 5478-5487 10 p.

Research output: Contribution to journalArticle

Flow cytometric analysis of lymphocyte profiles in mediastinal lymphadenopathy of sarcoidosis

Akao, K., Minezawa, T., Yamamoto, N., Okamura, T., Inoue, T., Yamatsuta, K., Uozu, S., Goto, Y., Hayashi, M., Isogai, S., Kondo, M. & Imaizumi, K., 11-2018, In : PloS one. 13, 11, e0206972.

Research output: Contribution to journalArticle

Generation of recombinant rotaviruses expressing fluorescent proteins by using an optimized reverse genetics system

Komoto, S., Fukuda, S., Ide, T., Ito, N., Sugiyama, M., Yoshikawa, T., Murata, T. & Taniguchi, K., 01-07-2018, In : Journal of Virology. 92, 13, e00588-18.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases

Kanai, M., Akiyama, M., Takahashi, A., Matoba, N., Momozawa, Y., Ikeda, M., Iwata, N., Ikegawa, S., Hirata, M., Matsuda, K., Kubo, M., Okada, Y. & Kamatani, Y., 01-03-2018, In : Nature Genetics. 50, 3, p. 390-400 11 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)

Genetic variants in CPA6 and PRPF31 are associated with variation in response to metformin in individuals with type 2 diabetes

Rotroff, D. M., Yee, S. W., Zhou, K., Marvel, S. W., Shah, H. S., Jack, J. R., Havener, T. M., Hedderson, M. M., Kubo, M., Herman, M. A., Gao, H., Mychaleckyi, J. C., McLeod, H. L., Doria, A., Giacomini, K. M., Pearson, E. R., Wagner, M. J., Buse, J. B. & Motsinger-Reif, A. A., 07-2018, In : Diabetes. 67, 7, p. 1428-1440 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Genetic variation determines VEGF-A plasma levels in cancer patients

Innocenti, F., Jiang, C., Sibley, A. B., Etheridge, A. S., Hatch, A. J., Denning, S., Niedzwiecki, D., Shterev, I. D., Lin, J., Furukawa, Y., Kubo, M., Kindler, H. L., Auman, J. T., Venook, A. P., Hurwitz, H. I., McLeod, H. L., Ratain, M. J., Gordan, R., Nixon, A. B. & Owzar, K., 01-12-2018, In : Scientific reports. 8, 1, 16332.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Lifelines Cohort Study, 01-12-2018, In : Nature communications. 9, 1, 4455.

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)
11 Citations (Scopus)

Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13.1

Yodsurang, V., Tang, Y., Takahashi, Y., Tanikawa, C., Kamatani, Y., Takahashi, A., Momozawa, Y., Fuse, N., Sugawara, J., Shimizu, A., Fukushima, A., Hishida, A., Furusyo, N., Naito, M., Wakai, K., Yamaji, T., Sawadai, N., Iwasaki, M., Tsugane, S., Hirata, M. & 3 others, Murakami, Y., Kubo, M. & Matsuda, K., 12-2018, In : PloS one. 13, 12, e0209096.

Research output: Contribution to journalArticle

Genome-wide association study for pollinosis identified two novel loci in interleukin (IL)-1B in a Japanese population

Fujii, R., Hishida, A., Wu, M. C., Kondo, T., Hattori, Y., Naito, M., Endoh, K., Nakatochi, M., Hamajima, N., Kubo, M., Kuriki, K. & Wakai, K., 01-02-2018, In : Nagoya journal of medical science. 80, 1, p. 109-120 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21

Tanikawa, C., Kamatani, Y., Toyoshima, O., Sakamoto, H., Ito, H., Takahashi, A., Momozawa, Y., Hirata, M., Fuse, N., Takai-Igarashi, T., Shimizu, A., Sasaki, M., Yamaji, T., Sawada, N., Iwasaki, M., Tsugane, S., Naito, M., Hishida, A., Wakai, K., Furusyo, N. & 13 others, Murakami, Y., Nakamura, Y., Imoto, I., Inazawa, J., Oze, I., Sato, N., Tanioka, F., Sugimura, H., Hirose, H., Yoshida, T., Matsuo, K., Kubo, M. & Matsuda, K., 12-2018, In : Cancer science. 109, 12, p. 4015-4024 10 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes

Chang, S. W., McDonough, C. W., Gong, Y., Johnson, T. A., Tsunoda, T., Gamazon, E. R., Perera, M. A., Takahashi, A., Tanaka, T., Kubo, M., Pepine, C. J., Johnson, J. A. & Cooper-Dehoff, R. M., 01-01-2018, In : Pharmacogenomics Journal. 18, 1, p. 106-112 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma

Japan Glaucoma Society Omics Group (JGS-OG) & NEIGHBORHOOD Consortium, 15-04-2018, In : Human molecular genetics. 27, 8, p. 1486-1496 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Genomewide association study of leisure-time exercise behavior in Japanese Adults

Hara, M., Hachiya, T., Sutoh, Y., Matsuo, K., Nishida, Y., Shimanoe, C., Tanaka, K., Shimizu, A., Ohnaka, K., Kawaguchi, T., Oze, I., Matsuda, F., Ito, H., Kawai, S., Hishida, A., Okada, R., Sasakabe, T., Hirata, A., Ibusuki, R., Nindita, Y. & 19 others, Furusyo, N., Ikezaki, H., Kuriyama, N., Ozaki, E., Mikami, H., Nakamura, Y., Suzuki, S., Hosono, A., Katsuura-Kamano, S., Arisawa, K., Kuriki, K., Endoh, K., Takashima, N., Kadota, A., Nakatochi, M., Momozawa, Y., Kubo, M., Naito, M. & Wakai, K., 01-12-2018, In : Medicine and Science in Sports and Exercise. 50, 12, p. 2433-2441 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Genome-Wide Association Study of Renal Function Traits: Results from the Japan Multi-Institutional Collaborative Cohort Study

Hishida, A., Nakatochi, M., Akiyama, M., Kamatani, Y., Nishiyama, T., Ito, H., Oze, I., Nishida, Y., Hara, M., Takashima, N., Turin, T. C., Watanabe, M., Suzuki, S., Ibusuki, R., Shimoshikiryo, I., Nakamura, Y., Mikami, H., Ikezaki, H., Furusyo, N., Kuriki, K. & 12 others, Endoh, K., Koyama, T., Matsui, D., Uemura, H., Arisawa, K., Sasakabe, T., Okada, R., Kawai, S., Naito, M., Momozawa, Y., Kubo, M. & Wakai, K., 01-06-2018, In : American Journal of Nephrology. 47, 5, p. 304-316 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Genome-wide association study suggests four variants influencing outcomes with ranibizumab therapy in exudative age-related macular degeneration

Akiyama, M., Takahashi, A., Momozawa, Y., Arakawa, S., Miya, F., Tsunoda, T., Ashikawa, K., Oshima, Y., Yasuda, M., Yoshida, S., Enaida, H., Tan, X., Yanagi, Y., Yasukawa, T., Ogura, Y., Nagai, Y., Takahashi, K., Fujisawa, K., Inoue, M., Arakawa, A. & 6 others, Tanaka, K., Yuzawa, M., Kadonosono, K., Sonoda, K. H., Ishibashi, T. & Kubo, M., 01-10-2018, In : Journal of Human Genetics. 63, 10, p. 1083-1091 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations

Wardell, C. P., Fujita, M., Yamada, T., Simbolo, M., Fassan, M., Karlic, R., Polak, P., Kim, J., Hatanaka, Y., Maejima, K., Lawlor, R. T., Nakanishi, Y., Mitsuhashi, T., Fujimoto, A., Furuta, M., Ruzzenente, A., Conci, S., Oosawa, A., Sasaki-Oku, A., Nakano, K. & 18 others, Tanaka, H., Yamamoto, Y., Michiaki, K., Kawakami, Y., Aikata, H., Ueno, M., Hayami, S., Gotoh, K., Ariizumi, S. I., Yamamoto, M., Yamaue, H., Chayama, K., Miyano, S., Getz, G., Scarpa, A., Hirano, S., Nakamura, T. & Nakagawa, H., 05-2018, In : Journal of Hepatology. 68, 5, p. 959-969 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab

Ingle, J. N., Kalari, K. R., Wickerham, D. L., Von Minckwitz, G., Fasching, P. A., Furukawa, Y., Mushiroda, T., Goetz, M. P., Barman, P., Carlson, E. E., Rastogi, P., Costantino, J. P., Cairns, J., Paik, S., Bear, H. D., Kubo, M., Wang, L., Wolmark, N. & Weinshilboum, R. M., 01-01-2018, In : Pharmacogenetics and genomics. 28, 6, p. 147-152 6 p.

Research output: Contribution to journalArticle

Germline pathogenic variants of 11 breast cancer genes in 7,051 Japanese patients and 11,241 controls

Momozawa, Y., Iwasaki, Y., Parsons, M. T., Kamatani, Y., Takahashi, A., Tamura, C., Katagiri, T., Yoshida, T., Nakamura, S., Sugano, K., Miki, Y., Hirata, M., Matsuda, K., Spurdle, A. B. & Kubo, M., 01-12-2018, In : Nature Communications. 9, 1, 4083.

Research output: Contribution to journalArticle

15 Citations (Scopus)

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

MEGASTROKE Consortium, 01-12-2018, In : Nature communications. 9, 1, 5141.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12

Tanikawa, C., Kamatani, Y., Takahashi, A., Momozawa, Y., Leveque, K., Nagayama, S., Mimori, K., Mori, M., Ishii, H., Inazawa, J., Yasuda, J., Tsuboi, A., Shimizu, A., Sasaki, M., Yamaji, T., Sawada, N., Iwasaki, M., Tsugane, S., Naito, M., Wakai, K. & 7 others, Koyama, T., Takezaki, T., Yuji, K., Murakami, Y., Nakamura, Y., Kubo, M. & Matsuda, K., 03-05-2018, In : Carcinogenesis. 39, 5, p. 652-660 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes

The International IBD Genetics Consortium, 01-12-2018, In : Nature communications. 9, 1, 2427.

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)

Identification and characterization of UDP-mannose in human cell lines and mouse organs: Differential distribution across brain regions and organs

Nakajima, K., Kizuka, Y., Yamaguchi, Y., Hirabayashi, Y., Takahashi, K., Yuzawa, Y. & Taniguchi, N., 01-01-2018, In : Biochemical and Biophysical Research Communications. 495, 1, p. 401-407 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Identification of a genomic region between SLC29A1 and HsP90AB1 associated with risk of bevacizumab-induced hypertension: CALGB 80405 (Alliance)

Li, M., Mulkey, F., Jiang, C., O'Neil, B. H., Schneider, B. P., Shen, F., Friedman, P. N., Momozawa, Y., Kubo, M., Niedzwiecki, D., Hochster, H. S., Lenz, H. J., Atkins, J. N., Rugo, H. S., Halabi, S., Kelly, W. K., McLeod, H. L., Innocenti, F., Ratain, M. J., Venook, A. P. & 2 others, Owzar, K. & Kroetz, D. L., 01-10-2018, In : Clinical Cancer Research. 24, 19, p. 4734-4744 11 p.

Research output: Contribution to journalArticle

Identification of miRNAs in cervical mucus as a novel diagnostic marker for cervical neoplasia

Kawai, S., Fujii, T., Kukimoto, I., Yamada, H., Yamamoto, N., Kuroda, M., Otani, S., Ichikawa, R., Nishio, E., Torii, Y. & Iwata, A., 01-12-2018, In : Scientific reports. 8, 1, 7070.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Innate immune activation of astrocytes impairs neurodevelopment via upregulation of follistatin-like 1 and interferon-induced transmembrane protein 3

Yamada, S., Itoh, N., Nagai, T., Nakai, T., Ibi, D., Nakajima, A., Nabeshima, T. & Yamada, K., 22-10-2018, In : Journal of Neuroinflammation. 15, 1, 295.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Integrated analysis of human genetic association study and mouse transcriptome suggests LBH and SHF genes as novel susceptible genes for amyloid-β accumulation in Alzheimer’s disease

Yamaguchi-Kabata, Y., Morihara, T., Ohara, T., Ninomiya, T., Takahashi, A., Akatsu, H., Hashizume, Y., Hayashi, N., Shigemizu, D., Boroevich, K. A., Ikeda, M., Kubo, M., Takeda, M. & Tsunoda, T., 01-07-2018, In : Human Genetics. 137, 6-7, p. 521-533 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Interethnic analyses of blood pressure loci in populations of East Asian and European descent

The International Genomics of Blood Pressure (iGEN-BP) Consortium, 01-12-2018, In : Nature communications. 9, 1, 5052.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Isolation of human monoclonal antibodies that bind to two different antigens and are encoded by germline VH and VL genes

Sumitomo-Kondo, M., Ukai, Y., Iba, Y., Ohshima, N., Miura, K., Takasaki, A., Kurosawa, Y. & Kurosawa, G., 05-09-2018, In : Biochemical and Biophysical Research Communications. 503, 2, p. 1141-1147 7 p.

Research output: Contribution to journalArticle

Laminin-332 regulates differentiation of human interfollicular epidermal stem cells

Yamada, T., Hasegawa, S., Miyachi, K., Date, Y., Inoue, Y., Yagami, A., Arima, M., Iwata, Y., Yamamoto, N., Nakata, S., Matsunaga, K., Sugiura, K. & Akamatsu, H., 04-2018, In : Mechanisms of Ageing and Development. 171, p. 37-46 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Modification of the associations of alcohol intake with serum low-density lipoprotein cholesterol and triglyceriwdes by ALDH2 and ADH1B polymorphisms in Japanese men

Sasakabe, T., Wakai, K., Kawai, S., Hishida, A., Naito, M., Suzuki, S., Nindita, Y., Arisawa, K., Kita, Y., Hara, M., Kuriyama, N., Hirata, A., Mikami, H., Oze, I., Kubo, M., Tanaka, H. & Hamajima, N., 01-01-2018, In : Journal of epidemiology. 28, 4, p. 185-193 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Demenais, F., Margaritte-Jeannin, P., Barnes, K. C., Cookson, W. O. C., Altmüller, J., Ang, W., Barr, R. G., Beaty, T. H., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E. & 155 others, Burkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., Couto Alves, A., Curtin, J. A., Custovic, A., Daley, D., De Jongste, J. C., Del-Rio-Navarro, B. E., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Freidin, M. B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Granell, R., Graves, P. E., Gudbjartsson, D. F., Haahtela, T., Heckbert, S. R., Heederik, D., Heinrich, J., Heliövaara, M., Henderson, J., Himes, B. E., Hirose, H., Hirschhorn, J. N., Hofman, A., Holt, P., Hottenga, J., Hudson, T. J., Hui, J., Imboden, M., Ivanov, V., Jaddoe, V. W. V., James, A., Janson, C., Jarvelin, M. R., Jarvis, D., Jones, G., Jonsdottir, I., Jousilahti, P., Kabesch, M., Kähönen, M., Kantor, D. B., Karunas, A. S., Khusnutdinova, E., Koppelman, G. H., Kozyrskyj, A. L., Kreiner, E., Kubo, M., Kumar, R., Kumar, A., Kuokkanen, M., Lahousse, L., Laitinen, T., Laprise, C., Lathrop, M., Lau, S., Lee, Y. A., Lehtimäki, T., Letort, S., Levin, A. M., Li, G., Liang, L., Loehr, L. R., London, S. J., Loth, D. W., Manichaikul, A., Marenholz, I., Martinez, F. J., Matheson, M. C., Mathias, R. A., Matsumoto, K., Mbarek, H., McArdle, W. L., Melbye, M., Melén, E., Meyers, D., Michel, S., Mohamdi, H., Musk, A. W., Myers, R. A., Nieuwenhuis, M. A. E., Noguchi, E., O'Connor, G. T., Ogorodova, L. M., Palmer, C. D., Palotie, A., Park, J. E., Pennell, C. E., Pershagen, G., Polonikov, A., Postma, D. S., Probst-Hensch, N., Puzyrev, V. P., Raby, B. A., Raitakari, O. T., Ramasamy, A., Rich, S. S., Robertson, C. F., Romieu, I., Salam, M. T., Salomaa, V., Schlünssen, V., Scott, R., Selivanova, P. A., Sigsgaard, T., Simpson, A., Siroux, V., Smith, L. J., Solodilova, M., Standl, M., Stefansson, K., Strachan, D. P., Stricker, B. H., Takahashi, A., Thompson, P. J., Thorleifsson, G., Thorsteinsdottir, U., Tiesler, C. M. T., Torgerson, D. G., Tsunoda, T., Uitterlinden, A. G., Van Der Valk, R. J. P., Vaysse, A., Vedantam, S., Von Berg, A., Von Mutius, E., Vonk, J. M., Waage, J., Wareham, N. J., Weiss, S. T., White, W. B., Wickman, M., Widén, E., Willemsen, G., Williams, L. K., Wouters, I. M., Yang, J. J., Zhao, J. H., Moffatt, M. F., Ober, C. & Nicolae, D. L., 01-01-2018, In : Nature Genetics. 50, 1, p. 42-50 9 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Neurology Working Group of the CHARGE Consortium, NINDS Stroke Genetics Network (SiGN), UK Young Lacunar DNA Study, MEGAST ROKE Consortium, AFGen Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Genomics of Blood Pressure (iGEN-BP) Consortium, INVENT Consortium, STA RNET BioBank Japan Cooperative Hospital Group, COMPASS Consortium, EPIC-CVD Consortium, EPIC-InterAct Consortium, International Stroke Genetics Consortium (ISGC) & METAST ROKE Consortium, 01-04-2018, In : Nature Genetics. 50, 4, p. 524-537 14 p.

Research output: Contribution to journalArticle

150 Citations (Scopus)

Multi-ethnic genome-wide association study for atrial fibrillation

Roselli, C., Chaffin, M. D., Weng, L. C., Aeschbacher, S., Ahlberg, G., Albert, C. M., Almgren, P., Alonso, A., Anderson, C. D., Aragam, K. G., Arking, D. E., Barnard, J., Bartz, T. M., Benjamin, E. J., Bihlmeyer, N. A., Bis, J. C., Bloom, H. L., Boerwinkle, E., Bottinger, E. B., Brody, J. A. & 198 others, Calkins, H., Campbell, A., Cappola, T. P., Carlquist, J., Chasman, D. I., Chen, L. Y., Chen, Y. D. I., Choi, E. K., Choi, S. H., Christophersen, I. E., Chung, M. K., Cole, J. W., Conen, D., Cook, J., Crijns, H. J., Cutler, M. J., Damrauer, S. M., Daniels, B. R., Darbar, D., Delgado, G., Denny, J. C., Dichgans, M., Dörr, M., Dudink, E. A., Dudley, S. C., Esa, N., Esko, T., Eskola, M., Fatkin, D., Felix, S. B., Ford, I., Franco, O. H., Geelhoed, B., Grewal, R. P., Gudnason, V., Guo, X., Gupta, N., Gustafsson, S., Gutmann, R., Hamsten, A., Harris, T. B., Hayward, C., Heckbert, S. R., Hernesniemi, J., Hocking, L. J., Hofman, A., Horimoto, A. R. V. R., Huang, J., Huang, P. L., Huffman, J., Ingelsson, E., Ipek, E. G., Ito, K., Jimenez-Conde, J., Johnson, R., Jukema, J. W., Kääb, S., Kähönen, M., Kamatani, Y., Kane, J. P., Kastrati, A., Kathiresan, S., Katschnig-Winter, P., Kavousi, M., Kessler, T., Kietselaer, B. L., Kirchhof, P., Kleber, M. E., Knight, S., Krieger, J. E., Kubo, M., Launer, L. J., Laurikka, J., Lehtimäki, T., Leineweber, K., Lemaitre, R. N., Li, M., Lim, H. E., Lin, H. J., Lin, H., Lind, L., Lindgren, C. M., Lokki, M. L., London, B., Loos, R. J. F., Low, S. K., Lu, Y., Lyytikäinen, L. P., Macfarlane, P. W., Magnusson, P. K., Mahajan, A., Malik, R., Mansur, A. J., Marcus, G. M., Margolin, L., Margulies, K. B., März, W., McManus, D. D., Melander, O., Mohanty, S., Montgomery, J. A., Morley, M. P., Morris, A. P., Müller-Nurasyid, M., Natale, A., Nazarian, S., Neumann, B., Newton-Cheh, C., Niemeijer, M. N., Nikus, K., Nilsson, P., Noordam, R., Oellers, H., Olesen, M. S., Orho-Melander, M., Padmanabhan, S., Pak, H. N., Paré, G., Pedersen, N. L., Pera, J., Pereira, A., Porteous, D., Psaty, B. M., Pulit, S. L., Pullinger, C. R., Rader, D. J., Refsgaard, L., Ribasés, M., Ridker, P. M., Rienstra, M., Risch, L., Roden, D. M., Rosand, J., Rosenberg, M. A., Rost, N., Rotter, J. I., Saba, S., Sandhu, R. K., Schnabel, R. B., Schramm, K., Schunkert, H., Schurman, C., Scott, S. A., Seppälä, I., Shaffer, C., Shah, S., Shalaby, A. A., Shim, J., Shoemaker, M. B., Siland, J. E., Sinisalo, J., Sinner, M. F., Slowik, A., Smith, A. V., Smith, B. H., Smith, J. G., Smith, J. D., Smith, N. L., Soliman, E. Z., Sotoodehnia, N., Stricker, B. H., Sun, A., Sun, H., Svendsen, J. H., Tanaka, T., Tanriverdi, K., Taylor, K. D., Teder-Laving, M., Teumer, A., Thériault, S., Trompet, S., Tucker, N. R., Tveit, A., Uitterlinden, A. G., Van Der Harst, P., Van Gelder, I. C., Van Wagoner, D. R., Verweij, N., Vlachopoulou, E., Völker, U., Wang, B., Weeke, P. E., Weijs, B., Weiss, R., Weiss, S., Wells, Q. S., Wiggins, K. L., Wong, J. A., Woo, D., Worrall, B. B., Yang, P. S., Yao, J., Yoneda, Z. T., Zeller, T., Zeng, L., Lubitz, S. A., Lunetta, K. L. & Ellinor, P. T., 01-09-2018, In : Nature Genetics. 50, 9, p. 1225-1233 9 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

Periostin antisense oligonucleotide suppresses bleomycin-induced formation of a lung premetastatic niche for melanoma

Semba, T., Sugihara, E., Kamoshita, N., Ueno, S., Fukuda, K., Yoshino, M., Takao, K., Yoshikawa, K., Izuhara, K., Arima, Y., Suzuki, M. & Saya, H., 05-2018, In : Cancer science. 109, 5, p. 1447-1454 8 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Preparation of induced pluripotent stem cells using human peripheral blood monocytes

Isogai, S., Yamamoto, N., Hiramatsu, N., Goto, Y., Hayashi, M., Kondo, M. & Imaizumi, K., 12-2018, In : Cellular Reprogramming. 20, 6, p. 347-355 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Protein-altering variants of PTPN2 in childhood-onset Type 1A diabetes

The Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes, 03-2018, In : Diabetic Medicine. 35, 3, p. 376-380 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Ritanserin, a serotonin-2 receptor antagonist, inhibits functional recovery after cerebral infarction

Mizutani, K., Sonoda, S. & Wakita, H., 03-01-2018, In : Neuroreport. 29, 1, p. 54-58 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)