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2014

Induction of interferon-induced transmembrane protein 3 gene expression by lipopolysaccharide in astrocytes

Nakajima, A., Ibi, D., Nagai, T., Yamada, S., Nabeshima, T. & Yamada, K., 15-12-2014, In : European Journal of Pharmacology. 745, p. 166-175 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics

Wu, A. C., Himes, B. E., Lasky-Su, J., Litonjua, A., Peters, S. P., Lima, J., Kubo, M., Tamari, M., Nakamura, Y., Qiu, W., Weiss, S. T. & Tantisira, K., 03-2014, In : Journal of Allergy and Clinical Immunology. 133, 3, p. 723-728.e3

Research output: Contribution to journalArticle

11 Citations (Scopus)

In situ visualization of plasma cells producing antibodies reactive to Porphyromonas gingivalis in periodontitis: The application of the enzyme-labeled antigen method

Mizutani, Y., Tsuge, S., Takeda, H., Hasegawa, Y., Shiogama, K., Onouchi, T., Inada, K., Sawasaki, T. & Tsutsumi, Y., 08-2014, In : Molecular Oral Microbiology. 29, 4, p. 156-173 18 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers

Shiraishi, Y., Fujimoto, A., Furuta, M., Tanaka, H., Chiba, K. I., Boroevich, K. A., Abe, T., Kawakami, Y., Ueno, M., Gotoh, K., Ariizumi, S. I., Shibuya, T., Nakano, K., Sasaki, A., Maejima, K., Kitada, R., Hayami, S., Shigekawa, Y., Marubashi, S., Yamada, T. & 11 others, Kubo, M., Ishikawa, O., Aikata, H., Arihiro, K., Ohdan, H., Yamamoto, M., Yamaue, H., Chayama, K., Tsunoda, T., Miyano, S. & Nakagawa, H., 19-12-2014, In : PloS one. 9, 12, e114263.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

Sinner, M. F., Tucker, N. R., Lunetta, K. L., Ozaki, K., Smith, J. G., Trompet, S., Bis, J. C., Lin, H., Chung, M. K., Nielsen, J. B., Lubitz, S. A., Krijthe, B. P., Magnani, J. W., Ye, J., Gollob, M. H., Tsunoda, T., Müller-Nurasyid, M., Lichtner, P., Peters, A., Dolmatova, E. & 35 others, Kubo, M., Smith, J. D., Psaty, B. M., Smith, N. L., Jukema, J. W., Chasman, D. I., Albert, C. M., Ebana, Y., Furukawa, T., Macfarlane, P. W., Harris, T. B., Darbar, D., Dörr, M., Holst, A. G., Svendsen, J. H., Hofman, A., Uitterlinden, A. G., Gudnason, V., Isobe, M., Malik, R., Dichgans, M., Rosand, J., Van Wagoner, D. R., Benjamin, E. J., Milan, D. J., Melander, O., Heckbert, S. R., Ford, I., Liu, Y., Barnard, J., Olesen, M. S., Stricker, B. H. C., Tanaka, T., Kääb, S. & Ellinor, P. T., 01-01-2014, In : Circulation. 130, 15, p. 1225-1235 11 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)

Large-scale genetic study in east Asians identifies six new loci associated with colorectal cancer risk

Zhang, B., Jia, W. H., Matsuda, K., Kweon, S. S., Matsuo, K., Xiang, Y. B., Shin, A., Jee, S. H., Kim, D. H., Cai, Q., Long, J., Shi, J., Wen, W., Yang, G., Zhang, Y., Li, C., Li, B., Guo, Y., Ren, Z., Ji, B. T. & 25 others, Pan, Z. Z., Takahashi, A., Shin, M. H., Matsuda, F., Gao, Y. T., Oh, J. H., Kim, S., Ahn, Y. O., Chan, A. T., Chang-Claude, J., Slattery, M. L., Gruber, S. B., Schumacher, F. R., Stenzel, S. L., Casey, G., Kim, H. R., Jeong, J. Y., Park, J. W., Li, H. L., Hosono, S., Cho, S. H., Kubo, M., Shu, X. O., Zeng, Y. X. & Zheng, W., 06-2014, In : Nature Genetics. 46, 6, p. 533-542 10 p.

Research output: Contribution to journalArticle

147 Citations (Scopus)

Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in cancer cells and promote redox adaptation

Ishimoto, T., Sugihara, H., Watanabe, M., Sawayama, H., Iwatsuki, M., Baba, Y., Okabe, H., Hidaka, K., Yokoyama, N., Miyake, K., Yoshikawa, M., Nagano, O., Komohara, Y., Takeya, M., Saya, H. & Baba, H., 04-2014, In : Carcinogenesis. 35, 5, p. 1003-1011 9 p.

Research output: Contribution to journalArticle

Open Access
54 Citations (Scopus)

Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

Wen, W., Zheng, W., Okada, Y., Takeuchi, F., Tabara, Y., Hwang, J. Y., Dorajoo, R., Li, H., Tsai, F. J., Yang, X., He, J., Wu, Y., He, M., Zhang, Y., Liang, J., Guo, X., Sheu, W. H. U. H., Delahanty, R., Guo, X., Kubo, M. & 89 others, Yamamoto, K., Ohkubo, T., Go, M. J. I., Liu, J. J. U., Gan, W., Chen, C. C., Gao, Y., Li, S., Lee, N. R., Wu, C., Zhou, X., Song, H., Yao, J., Lee, I. T., Long, J., Tsunoda, T., Akiyama, K., Takashima, N., Cho, Y. S. H., Ong, R. T. H., Lu, L., Chen, C. H., Tan, A., Rice, T. K., Adair, L. S., Gui, L., Allison, M., Lee, W. J., Cai, Q., Isomura, M., Umemura, S., Kim, Y. J. I., Seielstad, M., Hixson, J., Xiang, Y. B., Isono, M., Kim, B. J., Sim, X., Lu, W., Nabika, T., Lee, J., Lim, W. Y., Gao, Y. T., Takayanagi, R., Kang, D. H., Wong, T. Y. I., Hsiung, C. A. G., Wu, I. C., Juang, J. M. J. I., Shi, J., Choi, B. Y. O., Aung, T., Hu, F., Kim, M. K. Y., Lim, W. Y. E., Wang, T. D., Shin, M. H., Lee, J., Ji, B. T., Lee, Y. H., Young, T. L., Shin, D. H. O., Chun, B. Y., Cho, M. C., Han, B. G., Hwu, C. M., Assimes, T. L., Absher, D., Yan, X., Kim, E., Kuo, J. Z., Kwon, S., Taylor, K. D., Chen, Y. D. I., Rotter, J. I., Qi, L., Zhu, D., Wu, T., Mohlke, K. L., Gu, D., Mo, Z., Wu, J. Y., Lin, X., Miki, T., Tai, E. S., Lee, J. Y., Kato, N., Shu, X. O. & Tanaka, T., 15-10-2014, In : Human molecular genetics. 23, 20, p. 5492-5504 13 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)

Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians

Chen, P., Takeuchi, F., Lee, J. Y., Li, H., Wu, J. Y., Liang, J., Long, J., Tabara, Y., Goodarzi, M. O., Pereira, M. A., Kim, Y. J., Go, M. J., Stram, D. O., Vithana, E., Khor, C. C., Liu, J., Liao, J., Ye, X., Wang, Y., Lu, L. & 50 others, Young, T. L., Lee, J., Thai, A. C., Cheng, C. Y., Van Dam, R. M., Friedlander, Y., Heng, C. K., Koh, W. P., Chen, C. H., Chang, L. C., Pan, W. H., Qi, B., Isono, M., Zheng, W., Cai, Q., Gao, Y., Yamamoto, K., Ohnaka, K., Takayanagi, R., Kita, Y., Ueshima, H., Hsiung, C. A., Cui, J., Sheu, W. H. H., Rotter, J. I., Chen, Y. D. I., Hsu, C., Okada, Y., Kubo, M., Takahashi, A., Tanaka, T., Van Rooij, F. J. A., Ganesh, S. K., Huang, J., Huang, T., Yuan, J., Hwang, J. Y., Gross, M. D., Assimes, T. L., Miki, T., Shu, X. O., Qi, L., Chen, Y. T., Lin, X., Aung, T., Wong, T. Y., Teo, Y. Y., Kim, B. J., Kato, N. & Tai, E. S., 07-2014, In : Diabetes. 63, 7, p. 2551-2562 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

Lubitz, S. A., Lunetta, K. L., Lin, H., Arking, D. E., Trompet, S., Li, G., Krijthe, B. P., Chasman, D. I., Barnard, J., Kleber, M. E., Dörr, M., Ozaki, K., Smith, A. V., Müller-Nurasyid, M., Walter, S., Agarwal, S. K., Bis, J. C., Brody, J. A., Chen, L. Y., Everett, B. M. & 42 others, Ford, I., Franco, O. H., Harris, T. B., Hofman, A., Kääb, S., Mahida, S., Kathiresan, S., Kubo, M., Launer, L. J., Macfarlane, P. W., Magnani, J. W., McKnight, B., McManus, D. D., Peters, A., Psaty, B. M., Rose, L. M., Rotter, J. I., Silbernagel, G., Smith, J. D., Sotoodehnia, N., Stott, D. J., Taylor, K. D., Tomaschitz, A., Tsunoda, T., Uitterlinden, A. G., Van Wagoner, D. R., Völker, U., Völzke, H., Murabito, J. M., Sinner, M. F., Gudnason, V., Felix, S. B., März, W., Chung, M., Albert, C. M., Stricker, B. H., Tanaka, T., Heckbert, S. R., Jukema, J. W., Alonso, A., Benjamin, E. J. & Ellinor, P. T., 01-04-2014, In : Journal of the American College of Cardiology. 63, 12, p. 1200-1210 11 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Npas4 regulates Mdm2 and thus Dcx in experience-dependent dendritic spine development of newborn olfactory bulb interneurons

Yoshihara, S. I., Takahashi, H., Nishimura, N., Kinoshita, M., Asahina, R., Kitsuki, M., Tatsumi, K., Furukawa-Hibi, Y., Hirai, H., Nagai, T., Yamada, K. & Tsuboi, A., 07-08-2014, In : Cell Reports. 8, 3, p. 843-857 15 p.

Research output: Contribution to journalArticle

Open Access
23 Citations (Scopus)

Plasma dehydroepiandrosterone sulfate levels in patients with major depressive disorder correlate with remission during treatment with antidepressants

Morita, T., Senzaki, K., Ishihara, R., Umeda, K., Iwata, N., Nagai, T., Hida, H., Nabeshima, T., Yukawa, K., Ozaki, N. & Noda, Y., 05-2014, In : Human Psychopharmacology. 29, 3, p. 280-286 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance)

Chhibber, A., Mefford, J., Stahl, E. A., Pendergrass, S. A., Baldwin, R. M., Owzar, K., Li, M., Winer, E. P., Hudis, C. A., Zembutsu, H., Kubo, M., Nakamura, Y., McLeod, H. L., Ratain, M. J., Shulman, L. N., Ritchie, M. D., Plenge, R. M., Witte, J. S. & Kroetz, D. L., 08-2014, In : Pharmacogenomics Journal. 14, 4, p. 336-342 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese - Cross-sectional data from the J-MICC study

Hishida, A., Wakai, K., Naito, M., Suma, S., Sasakabe, T., Hamajima, N., Hosono, S., Horita, M., Turin, T. C., Suzuki, S., Kairupan, T. S., Mikami, H., Ohnaka, K., Watanabe, I., Uemura, H., Kubo, M. & Tanaka, H., 14-10-2014, In : Lipids in Health and Disease. 13, 1, 162.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus

Lee, P. S., Ohshima, N., Stanfield, R. L., Yu, W., Iba, Y., Okuno, Y., Kurosawa, Y. & Wilson, I. A., 10-04-2014, In : Nature Communications. 5, 3614.

Research output: Contribution to journalArticle

86 Citations (Scopus)

Renal cyclooxygenase products are higher and lipoxygenase products are lower in early disease in the pcy mouse model of adolescent nephronophthisis

Yamaguchi, T., Lysecki, C., Reid, A., Nagao, S. & Aukema, H. M., 01-01-2014, In : Lipids. 49, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia

Onouchi, T., Kobayashi, K., Sakai, K., Shimomura, A., Smits, R., Sumi-Ichinose, C., Kurosumi, M., Takao, K., Nomura, R., Iizuka-Kogo, A., Suzuki, H., Kondo, K., Akiyama, T., Miyakawa, T., Fodde, R. & Senda, T., 29-03-2014, In : Molecular brain. 7, 1, 21.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort

Shigemizu, D., Abe, T., Morizono, T., Johnson, T. A., Boroevich, K. A., Hirakawa, Y., Ninomiya, T., Kiyohara, Y., Kubo, M., Nakamura, Y., Maeda, S. & Tsunoda, T., 20-03-2014, In : PloS one. 9, 3, e92549.

Research output: Contribution to journalArticle

22 Citations (Scopus)

The effect of sevoflurane on developing A/J strain mouse embryos using a whole-embryo culture system - The incidence of cleft lip in culture embryos

Yamada, M., Yamamoto, N., Ohgami, S., Kanazawa, M., Harada, J., Ohno, N. & Natsume, N., 03-2014, In : In Vitro Cellular and Developmental Biology - Animal. 50, 3, p. 237-242 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Trans-ethnic meta-analysis of white blood cell phenotypes

CHARGE Hematology, COGENT & BioBank Japan Project (RIKEN) Working Groups, 20-12-2014, In : Human molecular genetics. 23, 25, p. 6944-6960 17 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Two types of antibodies are induced by vaccination with A/California/2009pdm virus: Binding near the sialic acid-binding pocket and neutralizing both H1N1 and H5N1 viruses

Ohshima, N., Kubota-Koketsu, R., Iba, Y., Okuno, Y. & Kurosawa, Y., 05-02-2014, In : PloS one. 9, 2, e87305.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Whole genomic analysis of porcine G10P[5] rotavirus strain P343 provides evidence for bovine-to-porcine interspecies transmission

Komoto, S., Pongsuwanna, Y., Ide, T., Wakuda, M., Guntapong, R., Dennis, F. E., Haga, K., Fujii, Y., Katayama, K. & Taniguchi, K., 01-01-2014, In : Veterinary Microbiology. 174, 3-4, p. 577-583 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2013

A genome-wide association study identifies 2 susceptibility loci for crohn's disease in a Japanese population

Yamazaki, K., Umeno, J., Takahashi, A., Hirano, A., Johnson, T. A., Kumasaka, N., Morizono, T., Hosono, N., Kawaguchi, T., Takazoe, M., Yamada, T., Suzuki, Y., Tanaka, H., Motoya, S., Hosokawa, M., Arimura, Y., Shinomura, Y., Matsui, T., Matsumoto, T., Iida, M. & 4 others, Tsunoda, T., Nakamura, Y., Kamatani, N. & Kubo, M., 04-2013, In : Gastroenterology. 144, 4, p. 781-788 8 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients

Chung, S., Low, S. K., Zembutsu, H., Takahashi, A., Kubo, M., Sasa, M. & Nakamura, Y., 11-09-2013, In : Breast Cancer Research. 15, 5, R81.

Research output: Contribution to journalArticle

17 Citations (Scopus)

A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region

Urabe, Y., Ochi, H., Kato, N., Kumar, V., Takahashi, A., Muroyama, R., Hosono, N., Otsuka, M., Tateishi, R., Lo, P. H. Y., Tanikawa, C., Omata, M., Koike, K., Miki, D., Abe, H., Kamatani, N., Toyota, J., Kumada, H., Kubo, M., Chayama, K. & 2 others, Nakamura, Y. & Matsuda, K., 01-05-2013, In : Journal of Hepatology. 58, 5, p. 875-882 8 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: Effects of *09:01 allele on disease phenotypes

Shimane, K., Kochi, Y., Suzuki, A., Okada, Y., Ishii, T., Horita, T., Saito, K., Okamoto, A., Nishimoto, N., Myouzen, K., Kubo, M., Hirakata, M., Sumida, T., Takasaki, Y., Yamada, R., Nakamura, Y., Kamatani, N. & Yamamoto, K., 01-07-2013, In : Rheumatology (United Kingdom). 52, 7, p. 1172-1182 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

A practical method to detect SNVs and indels from whole genome and exome sequencing data

Shigemizu, D., Fujimoto, A., Akiyama, S., Abe, T., Nakano, K., Boroevich, K. A., Yamamoto, Y., Furuta, M., Kubo, M., Nakagawa, H. & Tsunoda, T., 23-07-2013, In : Scientific reports. 3, 2161.

Research output: Contribution to journalArticle

23 Citations (Scopus)

A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population

Yasui, T., Okada, A., Urabe, Y., Usami, M., Mizuno, K., Kubota, Y., Tozawa, K., Sasaki, S., Higashi, Y., Sato, Y., Kubo, M., Nakamura, Y., Matsuda, K. & Kohri, K., 01-09-2013, In : Journal of Human Genetics. 58, 9, p. 588-593 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Arf and p53 act as guardians of a quiescent cellular state by protecting against immortalization of cells with stable genomes

Osawa, T., Atsumi, Y., Sugihara, E., Saya, H., Kanno, M., Tashiro, F., Masutani, M. & Yoshioka, K. I., 01-03-2013, In : Biochemical and Biophysical Research Communications. 432, 1, p. 34-39 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Association study of 71 European Crohn's disease susceptibility loci in a Japanese population

Hirano, A., Yamazaki, K., Umeno, J., Ashikawa, K., Aoki, M., Matsumoto, T., Nakamura, S., Ninomiya, T., Matsui, T., Hirai, F., Kawaguchi, T., Takazoe, M., Tanaka, H., Motoya, S., Kiyohara, Y., Kitazono, T., Nakamura, Y., Kamatani, N. & Kubo, M., 01-03-2013, In : Inflammatory Bowel Diseases. 19, 3, p. 526-533 8 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Circadian expressions of cardiac ion channel genes in mouse might be associated with the central clock in the SCN but not the peripheral clock in the heart

Tong, M., Watanabe, E., Yamamoto, N., Nagahata-Ishiguro, M., Maemura, K., Takeda, N., Nagai, R. & Ozaki, Y., 01-08-2013, In : Biological Rhythm Research. 44, 4, p. 519-530 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type

Rust, S., Guillard, S., Sachsenmeier, K., Hay, C., Davidson, M., Karlsson, A., Karlsson, R., Brand, E., Lowne, D., Elvin, J., Flynn, M., Kurosawa, G., Hollingsworth, R., Jermutus, L. & Minter, R., 13-02-2013, In : Molecular Cancer. 12, 1, 11.

Research output: Contribution to journalArticle

Open Access
37 Citations (Scopus)

Comparative analysis in cynomolgus macaque identifies a novel human MHC locus controlling platelet blood counts independently of BAK1

Aarnink, A., Garchon, H. J., Okada, Y., Takahashi, A., Matsuda, K., Kubo, M., Nakamura, Y. & Blancher, A., 01-02-2013, In : Journal of Thrombosis and Haemostasis. 11, 2, p. 384-386 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia

Takao, K., Kobayashi, K., Hagihara, H., Ohira, K., Shoji, H., Hattori, S., Koshimizu, H., Umemori, J., Toyama, K., Nakamura, H. K., Kuroiwa, M., Maeda, J., Atsuzawa, K., Esaki, K., Yamaguchi, S., Furuya, S., Takagi, T., Walton, N. M., Hayashi, N., Suzuki, H. & 7 others, Higuchi, M., Usuda, N., Suhara, T., Nishi, A., Matsumoto, M., Ishii, S. & Miyakawa, T., 01-07-2013, In : Neuropsychopharmacology. 38, 8, p. 1409-1425 17 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)

Effects of exercise after focal cerebral cortex infarction on basal ganglion

Mizutani, K., Sonoda, S., Karasawa, N., Yamada, K., Shimpo, K., Chihara, T., Takeuchi, T., Hasegawa, Y. & Kubo, K. Y., 01-06-2013, In : Neurological Sciences. 34, 6, p. 861-867 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Evaluation of 89Zr-Labeled Human Anti-CD147 Monoclonal Antibody as a Positron Emission Tomography Probe in a Mouse Model of Pancreatic Cancer

Sugyo, A., Tsuji, A. B., Sudo, H., Nagatsu, K., Koizumi, M., Ukai, Y., Kurosawa, G., Zhang, M. R., Kurosawa, Y. & Saga, T., 05-04-2013, In : PloS one. 8, 4, e61230.

Research output: Contribution to journalArticle

Open Access
20 Citations (Scopus)

Exceptionally high conservation of the MHC class I-related gene, MR1, among mammals

Tsukamoto, K., Deakin, J. E., Graves, J. A. M. & Hashimoto, K., 01-02-2013, In : Immunogenetics. 65, 2, p. 115-124 10 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Functional role of CD44v-xCT system in the development of spasmolytic polypeptide-expressing metaplasia

Wada, T., Ishimoto, T., Seishima, R., Tsuchihashi, K., Yoshikawa, M., Oshima, H., Oshima, M., Masuko, T., Wright, N. A., Furuhashi, S., Hirashima, K., Baba, H., Kitagawa, Y., Saya, H. & Nagano, O., 01-10-2013, In : Cancer science. 104, 10, p. 1323-1329 7 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Gene-gene combination effect and interactions among ABCA1, APOA1, SR-B1, and CETP polymorphisms for serum high-density lipoprotein-cholesterol in the japanese population

Nakamura, A., Niimura, H., Kuwabara, K., Takezaki, T., Morita, E., Wakai, K., Hamajima, N., Nishida, Y., Turin, T. C., Suzuki, S., Ohnaka, K., Uemura, H., Ozaki, E., Hosono, S., Mikami, H., Kubo, M. & Tanaka, H., 20-12-2013, In : PloS one. 8, 12, e82046.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema

Pare, G., Kubo, M., Byrd, J. B., McCarty, C. A., Woodard-Grice, A., Teo, K. K., Anand, S. S., Zuvich, R. L., Bradford, Y., Ross, S., Nakamura, Y., Ritchie, M. & Brown, N. J., 01-09-2013, In : Pharmacogenetics and genomics. 23, 9, p. 470-478 9 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Genetic variants associated with warfarin dose in African-American individuals: A genome-wide association study

Perera, M. A., Cavallari, L. H., Limdi, N. A., Gamazon, E. R., Konkashbaev, A., Daneshjou, R., Pluzhnikov, A., Crawford, D. C., Wang, J., Liu, N., Tatonetti, N., Bourgeois, S., Takahashi, H., Bradford, Y., Burkley, B. M., Desnick, R. J., Halperin, J. L., Khalifa, S. I., Langaee, T. Y., Lubitz, S. A. & 22 others, Nutescu, E. A., Oetjens, M., Shahin, M. H., Patel, S. R., Sagreiya, H., Tector, M., Weck, K. E., Rieder, M. J., Scott, S. A., Wu, A. H. B., Burmester, J. K., Wadelius, M., Deloukas, P., Wagner, M. J., Mushiroda, T., Kubo, M., Roden, D. M., Cox, N. J., Altman, R. B., Klein, T. E., Nakamura, Y. & Johnson, J. A., 01-01-2013, In : The Lancet. 382, 9894, p. 790-796 7 p.

Research output: Contribution to journalArticle

155 Citations (Scopus)

Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis

Kou, I., Takahashi, Y., Johnson, T. A., Takahashi, A., Guo, L., Dai, J., Qiu, X., Sharma, S., Takimoto, A., Ogura, Y., Jiang, H., Yan, H., Kono, K., Kawakami, N., Uno, K., Ito, M., Minami, S., Yanagida, H., Taneichi, H., Hosono, N. & 21 others, Tsuji, T., Suzuki, T., Sudo, H., Kotani, T., Yonezawa, I., Londono, D., Gordon, D., Herring, J. A., Watanabe, K., Chiba, K., Kamatani, N., Jiang, Q., Hiraki, Y., Kubo, M., Toyama, Y., Tsunoda, T., Wise, C. A., Qiu, Y., Shukunami, C., Matsumoto, M. & Ikegawa, S., 01-06-2013, In : Nature Genetics. 45, 6, p. 676-679 4 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)

Genome wide analysis of drug-induced torsades de pointes: Lack of common variants with large effect sizes

Behr, E. R., Ritchie, M. D., Tanaka, T., Kääb, S., Crawford, D. C., Nicoletti, P., Floratos, A., Sinner, M. F., Kannankeril, P. J., Wilde, A. A. M., Bezzina, C. R., Schulze-Bahr, E., Zumhagen, S., Guicheney, P., Bishopric, N. H., Marshall, V., Shakir, S., Dalageorgou, C., Bevan, S., Jamshidi, Y. & 14 others, Bastiaenen, R., Myerburg, R. J., Schott, J. J., Camm, A. J., Steinbeck, G., Norris, K., Altman, R. B., Tatonetti, N. P., Jeffery, S., Kubo, M., Nakamura, Y., Shen, Y., George, A. L. & Roden, D. M., 06-11-2013, In : PloS one. 8, 11, e78511.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Genome-wide association analysis of red blood cell traits in African Americans: The cogent network

Chen, Z., Tang, H., Qayyum, R., Schick, U. M., Nalls, M. A., Handsaker, R., Li, J., Lu, Y., Yanek, L. R., Keating, B., Meng, Y., Van Rooij, F. J. A., Okada, Y., Kubo, M., Rasmussen-Torvik, L., Keller, M. F., Lange, L., Evans, M., Bottinger, E. P., Linderman, M. D. & 16 others, Ruderfer, D. M., Hakonarson, H., Papanicolaou, G., Zonderman, A. B., Gottesman, O., Thomson, C., Ziv, E., Singleton, A. B., Loos, R. J. F., Sleiman, P. M. A., Ganesh, S., McCarroll, S., Becker, D. M., Wilson, J. G., Lettre, G. & Reiner, A. P., 01-06-2013, In : Human molecular genetics. 22, 12, p. 2529-2538 10 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Genome Wide Association Study of Age at Menarche in the Japanese Population

Tanikawa, C., Okada, Y., Takahashi, A., Oda, K., Kamatani, N., Kubo, M., Nakamura, Y. & Matsuda, K., 07-05-2013, In : PloS one. 8, 5, e63821.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Genome-Wide Association Study of Breast Cancer in the Japanese Population

Low, S. K., Takahashi, A., Ashikawa, K., Inazawa, J., Miki, Y., Kubo, M., Nakamura, Y. & Katagiri, T., 15-10-2013, In : PloS one. 8, 10, e76463.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan

Low, S. K., Chung, S., Takahashi, A., Zembutsu, H., Mushiroda, T., Kubo, M. & Nakamura, Y., 08-2013, In : Cancer science. 104, 8, p. 1074-1082 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Genome-wide association study of genetic factors related to confectionery intake: Potential roles of the ADIPOQ gene

Wakai, K., Matsuo, K., Matsuda, F., Yamada, R., Takahashi, M., Kawaguchi, T., Yatabe, Y., Ito, H., Hosono, S., Tajima, K., Naito, M., Morita, E., Yin, G., Sakamoto, T., Takashima, N., Suzuki, S., Nakahata, N., Mikami, H., Ohnaka, K., Watanabe, Y. & 4 others, Arisawa, K., Kubo, M., Hamajima, N. & Tanaka, H., 01-11-2013, In : Obesity. 21, 11, p. 2413-2419 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

High-density genotyping study identifies four new susceptibility loci for atopic dermatitis

Ellinghaus, D., Baurecht, H., Esparza-Gordillo, J., Rodríguez, E., Matanovic, A., Marenholz, I., Hübner, N., Schaarschmidt, H., Novak, N., Michel, S., Maintz, L., Werfel, T., Meyer-Hoffert, U., Hotze, M., Prokisch, H., Heim, K., Herder, C., Hirota, T., Tamari, M., Kubo, M. & 29 others, Takahashi, A., Nakamura, Y., Tsoi, L. C., Stuart, P., Elder, J. T., Sun, L., Zuo, X., Yang, S., Zhang, X., Hoffmann, P., Nöthen, M. M., Fölster-Holst, R., Winkelmann, J., Illig, T., Boehm, B. O., Duerr, R. H., Büning, C., Brand, S., Glas, J., McAleer, M. A., Fahy, C. M., Kabesch, M., Brown, S., McLean, W. H. I., Irvine, A. D., Schreiber, S., Lee, Y. A., Franke, A. & Weidinger, S., 01-07-2013, In : Nature Genetics. 45, 7, p. 808-812 5 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: A genome-wide association study

Miki, D., Ochi, H., Takahashi, A., Hayes, C. N., Urabe, Y., Abe, H., Kawaoka, T., Tsuge, M., Hiraga, N., Imamura, M., Kawakami, Y., Aikata, H., Takahashi, S., Akuta, N., Suzuki, F., Ikeda, K., Kumada, H., Karino, Y., Toyota, J., Tsunoda, T. & 4 others, Kubo, M., Kamatani, N., Nakamura, Y. & Chayama, K., 20-12-2013, In : PloS one. 8, 12, e84226.

Research output: Contribution to journalArticle

24 Citations (Scopus)