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Review article
2020

Mass spectrometry for the identification and analysis of highly complex glycosylation of therapeutic or pathogenic proteins

Ohyama, Y., Nakajima, K., Renfrow, M. B., Novak, J. & Takahashi, K., 02-04-2020, In : Expert Review of Proteomics. 17, 4, p. 275-296 22 p.

Research output: Contribution to journalReview article

Molecular and cellular mechanisms underlying brain metastasis of breast cancer

Hosonaga, M., Saya, H. & Arima, Y., 01-09-2020, In : Cancer and Metastasis Reviews. 39, 3, p. 711-720 10 p.

Research output: Contribution to journalReview article

Open Access
2019

An evolving story of the metastatic voyage of ovarian cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment

Motohara, T., Masuda, K., Morotti, M., Zheng, Y., El-Sahhar, S., Chong, K. Y., Wietek, N., Alsaadi, A., Karaminejadranjbar, M., Hu, Z., Artibani, M., Gonzalez, L. S., Katabuchi, H., Saya, H. & Ahmed, A. A., 18-04-2019, In : Oncogene. 38, 16, p. 2885-2898 14 p.

Research output: Contribution to journalReview article

Open Access
15 Citations (Scopus)

A novel PAK3 pathogenic variant identified in two siblings from a Japanese family with X-linked intellectual disability: Case report and review of the literature

Iida, A., Takano, K., Takeshita, E., Abe-Hatano, C., Hirabayashi, S., Inaba, Y., Kosugi, S., Kamatani, Y., Momozawa, Y., Kubo, M., Nakagawa, E., Inoue, K. & Goto, Y. I., 01-01-2019, In : Cold Spring Harbor Molecular Case Studies. 5, 6, a003988.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)
Open Access

Regulation of IgA production by intestinal dendritic cells and related cells

Tezuka, H. & Ohteki, T., 2019, In : Frontiers in Immunology. 10, AUG, 1891.

Research output: Contribution to journalReview article

Open Access
5 Citations (Scopus)

令和元年度放射線安全規制研究戦略的推進事業 / 日本保健物理学会放射線防護標準化委員会「シンポジウム:水晶体防護に係るガイドラインを考える」

Translated title of the contribution: Symposium; Guideline for Radiation Protection of the Lens of the EyeYokoyama, S., 01-01-2019, In : Japanese Journal of Health Physics. 54, 4, p. 213-216 4 p.

Research output: Contribution to journalReview article

Open Access
2018

Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients

on behalf of the MATURA, and PAMERA & Consortia, 01-07-2018, In : Pharmacogenomics Journal. 18, 4, p. 528-538 11 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)

Modeling phenotypes of malignant gliomas

Sampetrean, O. & Saya, H., 01-2018, In : Cancer science. 109, 1, p. 6-14 9 p.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)
2017

Telomere length as a potential biomarker of coronary artery disease

Bhattacharyya, J., Mihara, K., Bhattacharjee, D. & Mukherjee, M., 06-2017, In : Indian Journal of Medical Research. 145, June, p. 730-737 8 p.

Research output: Contribution to journalReview article

Open Access
14 Citations (Scopus)
2016
1 Citation (Scopus)

Molecular mechanism linking BDNF/TrkB signaling with the NMDA receptor in memory: The role of Girdin in the CNS

Itoh, N., Enomoto, A., Nagai, T., Takahashi, M. & Yamada, K., 01-07-2016, In : Reviews in the Neurosciences. 27, 5, p. 481-490 10 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)

Phosphorylation Signals in Striatal Medium Spiny Neurons

Nagai, T., Yoshimoto, J., Kannon, T., Kuroda, K. & Kaibuchi, K., 01-10-2016, In : Trends in Pharmacological Sciences. 37, 10, p. 858-871 14 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)

Therapeutic strategies targeting cancer stem cells

Yoshida, G. J. & Saya, H., 01-01-2016, In : Cancer science. 107, 1, p. 5-11 7 p.

Research output: Contribution to journalReview article

Open Access
117 Citations (Scopus)
2015

Along the axis between type 1 and type 2 immunity; principles conserved in evolution from fish to mammals

Yamaguchi, T., Takizawa, F., Fischer, U. & Dijkstra, J. M., 17-11-2015, In : Biology. 4, 4, p. 814-859 46 p.

Research output: Contribution to journalReview article

27 Citations (Scopus)

Global implementation of genomic medicine: We are not alone

Manolio, T. A., Abramowicz, M., Al-Mulla, F., Anderson, W., Balling, R., Berger, A. C., Bleyl, S., Chakravarti, A., Chantratita, W., Chisholm, R. L., Dissanayake, V. H. W., Dunn, M., Dzau, V. J., Han, B. G., Hubbard, T., Kolbe, A., Korf, B., Kubo, M., Lasko, P., Leego, E. & 24 others, Mahasirimongkol, S., Majumdar, P. P., Matthijs, G., McLeod, H. L., Metspalu, A., Meulien, P., Miyano, S., Naparstek, Y., O'Rourke, P. P., Patrinos, G. P., Rehm, H. L., Relling, M. V., Rennert, G., Rodriguez, L. L., Roden, D. M., Shuldiner, A. R., Sinha, S., Tan, P., Ulfendahl, M., Ward, R., Williams, M. S., Wong, J. E. L., Green, E. D. & Ginsburg, G. S., 03-06-2015, In : Science Translational Medicine. 7, 290, 290ps13.

Research output: Contribution to journalReview article

90 Citations (Scopus)
2012

[Functional analysis of stress-responsible transcription factor Npas4 in stress-induced brain dysfunction].

Nagai, T., Yun, J., Ibi, D., Koike, H., Hibi, Y. & Yamada, K., 01-04-2012, In : Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 139, 4, p. 147-151 5 p.

Research output: Contribution to journalReview article

Open Access

Animal models for human polycystic kidney disease

Nagao, S., Kugita, M., Yoshihara, D. & Yamaguchi, T., 01-12-2012, In : Experimental animals. 61, 5, p. 477-488 12 p.

Research output: Contribution to journalReview article

37 Citations (Scopus)

Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis

Mahasirimongkol, S., Yanai, H., Mushiroda, T., Promphittayarat, W., Wattanapokayakit, S., Phromjai, J., Yuliwulandari, R., Wichukchinda, N., Yowang, A., Yamada, N., Kantipong, P., Takahashi, A., Kubo, M., Sawanpanyalert, P., Kamatani, N., Nakamura, Y. & Tokunaga, K., 06-2012, In : Journal of Human Genetics. 57, 6, p. 363-367 5 p.

Research output: Contribution to journalReview article

69 Citations (Scopus)

Integrated approach toward the discovery of glyco-biomarkers of inflammation-Related diseases

Angata, T., Fujinawa, R., Kurimoto, A., Nakajima, K., Kato, M., Takamatsu, S., Korekane, H., Gao, C. X., Ohtsubo, K., Kitazume, S. & Taniguchi, N., 04-2012, In : Annals of the New York Academy of Sciences. 1253, 1, p. 159-169 11 p.

Research output: Contribution to journalReview article

31 Citations (Scopus)

PPAR-γ agonists in polycystic kidney disease with frequent development of cardiovascular disorders

Nagao, S. & Yamaguchi, T., 06-2012, In : Current Molecular Pharmacology. 5, 2, p. 292-300 9 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)

Prostate cancer genomics, biology, and risk assessment through genome-wide association studies

Nakagawa, H., Akamatsu, S., Takata, R., Takahashi, A., Kubo, M. & Nakamura, Y., 04-2012, In : Cancer science. 103, 4, p. 607-613 7 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)

Stimulation-dependent intraspinal microtubules and synaptic failure in Alzheimer's disease: A review

Mitsuyama, F., Futatsugi, Y., Okuya, M., Kawase, T., Karagiozov, K., Kato, Y., Kanno, T., Sano, H., Nagao, S. & Koide, T., 2012, In : International Journal of Alzheimer's Disease. 519682.

Research output: Contribution to journalReview article

4 Citations (Scopus)

The Clinical Significance of Thymidylate Synthase Expression in Human Papillomavirus - Related Oropharyngeal Squamous Carcinoma

Kato, H., Yui, T., Yamamoto, N., Okada, T., Urano, M., Sakurai, K. & Naito, K., 01-11-2012, In : Journal of Otolaryngology of Japan. 115, 11, p. 957-964 8 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2011

[Encounter of cancer cells with bone. The significance of cancer stem cells and epithelial-mesenchymal transition in tumor invasion and metastasis].

Yoshida, G. J. & Saya, H., 01-03-2011, In : Clinical calcium. 21, 3, p. 411-417 7 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

[Genome-wide association study for ischemic stroke based on the Hisayama study].

Hata, J., Kubo, M. & Kiyohara, Y., 01-2011, In : Nihon eiseigaku zasshi. Japanese journal of hygiene. 66, 1, p. 47-52 6 p.

Research output: Contribution to journalReview article

11 Citations (Scopus)

Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash

Chantarangsu, S., Mushiroda, T., Mahasirimongkol, S., Kiertiburanakul, S., Sungkanuparph, S., Manosuthi, W., Tantisiriwat, W., Charoenyingwattana, A., Sura, T., Takahashi, A., Kubo, M., Kamatani, N., Chantratita, W. & Nakamura, Y., 15-08-2011, In : Clinical Infectious Diseases. 53, 4, p. 341-348 8 p.

Research output: Contribution to journalReview article

42 Citations (Scopus)

Hypoxic regulation of glycosylation via the N-acetylglucosamine cycle

Shirato, K., Nakajima, K., Korekane, H., Takamatsu, S., Gao, C., Angata, T., Ohtsubo, K. & Taniguchi, N., 01-2011, In : Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 20-25 6 p.

Research output: Contribution to journalReview article

38 Citations (Scopus)
2010

[Recent advances in the genome-wide association study of common diseases].

Kubo, M., 08-2010, In : Nippon rinsho. Japanese journal of clinical medicine. 68 Suppl 8, p. 129-133 5 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2009

[Mitotic regulation and carcinogenesis].

Saya, H., Zhang, D. & Oltea, S., 01-03-2009, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 54, 4 Suppl, p. 561-567 7 p.

Research output: Contribution to journalReview article

Molecularly targeted therapies for glioma

Yamanaka, R. & Saya, H., 12-2009, In : Annals of Neurology. 66, 6, p. 717-729 13 p.

Research output: Contribution to journalReview article

22 Citations (Scopus)

Present and future of reverse genetics of rotavirus

Taniguchi, K., Komoto, S., Sasaki, J. & Kugita, M., 06-2009, In : Uirusu. Journal of virology. 59, 1, p. 91-98 8 p.

Research output: Contribution to journalReview article

2008

Role of CD44-mediated signal in cancer invasion and metastasis

Saya, H. & Nagano, O., 01-08-2008, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 53, 10, p. 1225-1230 6 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)
2007

Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia

Senda, T., Iizuka-Kogo, A., Onouchi, T. & Shimomura, A., 01-06-2007, In : Medical Molecular Morphology. 40, 2, p. 68-81 14 p.

Research output: Contribution to journalReview article

80 Citations (Scopus)

Aurora kinases: Functions and roles in tumorigenesis

Saya, H., 01-12-2007, In : Seikagaku. 79, 2, p. 131-139 9 p.

Research output: Contribution to journalReview article

Behavioral analyses for learning and memory in mice and rats

Takuma, K., Nagai, T. & Yamada, K., 01-12-2007, In : Folia Pharmacologica Japonica. 130, 2, p. 112-116 5 p.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)
2006

Dynamics of mitotic spindle

Kinoshita, K. & Saya, H., 01-05-2006, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.. 51, 6 Suppl, p. 761-766 6 p.

Research output: Contribution to journalReview article

Molecular mechanisms of anti-cancer therapies

Saya, H., 10-2006, In : Japanese Journal of Neurosurgery. 15, 10, p. 688-693 6 p.

Research output: Contribution to journalReview article

Open Access
2005

Aurora-A - A guardian of poles

Marumoto, T., Zhang, D. & Saya, H., 01-01-2005, In : Nature Reviews Cancer. 5, 1, p. 42-50 9 p.

Research output: Contribution to journalReview article

558 Citations (Scopus)

Behavioral approaches for analyzing emotionality in mutant mice

Nagai, T., Yamada, K. & Nabeshima, T., 11-03-2005, In : Folia Pharmacologica Japonica. 125, 2, p. 71-76 6 p.

Research output: Contribution to journalReview article

Pro- and anti-addictive factors related to drug addiction

Yamada, K., Nagai, T., Nakajima, A. & Nabeshima, T., 29-07-2005, In : Folia Pharmacologica Japonica. 126, 1, p. 49-53 5 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Relationship between obesity, glucose tolerance, and periodontal disease in Japanese women: The Hisayama study

Saito, T., Shimazaki, Y., Kiyohara, Y., Kato, I., Kubo, M., Iida, M. & Yamashita, Y., 01-08-2005, In : Journal of Periodontal Research. 40, 4, p. 346-353 8 p.

Research output: Contribution to journalReview article

151 Citations (Scopus)
2004

Mechanism and biological significance of CD44 cleavage

Nagano, O. & Saya, H., 12-2004, In : Cancer science. 95, 12, p. 930-935 6 p.

Research output: Contribution to journalReview article

282 Citations (Scopus)
2002

Two-step strategy for alteration of immunoglobulin specificity by in vitro mutagenesis.

Iba, Y., Miyazaki, C. & Kurosawa, Y., 2002, In : Methods in molecular biology (Clifton, N.J.). 178, p. 259-267 9 p.

Research output: Contribution to journalReview article

2001

Comparative genomics of small laboratory fish

Hori, H. & Kurosawa, G., 12-2001, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 46, 16 Suppl, p. 2468-2472 5 p.

Research output: Contribution to journalReview article

2000

Calpain-dependent proteolysis of NF2 protein: Involvement in schwannomas and meningiomas

Kimura, Y., Saya, H. & Nakao, M., 2000, In : Neuropathology. 20, 3, p. 153-160 8 p.

Research output: Contribution to journalReview article

28 Citations (Scopus)
1995

Methylprednisolone retards the progression of inherited polycystic kidney disease in rodents

Gattone, V. H., Cowley, B. D., Barash, B. D., Nagao, S., Takahashi, H., Yamaguchi, T. & Grantham, J. J., 02-1995, In : American Journal of Kidney Diseases. 25, 2, p. 302-313 12 p.

Research output: Contribution to journalReview article

62 Citations (Scopus)

Phenotypic analysis of myeloma cells

Mihara, K., Harada, H. & Kawano, M. M., 01-03-1995, In : Nippon rinsho. Japanese journal of clinical medicine. 53, 3, p. 574-579 6 p.

Research output: Contribution to journalReview article