School of Medicine

Research Output

Article

Increased heteroscedasticity of heart rate in fatal heart failure

Struzik, Z. R., Kiyono, K., Hayano, J., Watanabe, E. & Yamamoto, Y., 01-04-2008, In : EPL. 82, 2, 28005.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Increased hydrogen peroxide generation by neutrophils from patients with acne inflammation

Akamatsu, H., Horio, T. & Hattori, K., 01-05-2003, In : International Journal of Dermatology. 42, 5, p. 366-369 4 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Increased hydrophobicity in Malassezia species correlates with increased proinflammatory cytokine expression in human keratinocytes

Akaza, N., Akamatsu, H., Takeoka, S., Mizutani, H., Nakata, S. & Matsunaga, K., 01-11-2012, In : Medical Mycology. 87, 8, p. 802-810 9 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Increased infiltration of CCR4-positive regulatory T cells in prostate cancer tissue is associated with a poor prognosis

Watanabe, M., Kanao, K., Suzuki, S., Muramatsu, H., Morinaga, S., Kajikawa, K., Kobayashi, I., Nishikawa, G., Kato, Y., Zannami, K., Nakamura, K., Tsuzuki, T., Yoshikawa, K., Ueda, R. & Sumitomo, M., 01-01-2019, In : Prostate. 79, 14, p. 1658-1665 8 p.

Research output: Contribution to journalArticle

Increased levels of cytokines and high-mobility group box 1 are associated with the development of severe pneumonia, but not acute encephalopathy, in 2009 H1N1 influenza-infected children

Ito, Y., Torii, Y., Ohta, R., Imai, M., Hara, S., Kawano, Y., Matsubayashi, T., Inui, A., Yoshikawa, T., Nishimura, N., Ozaki, T., Morishima, T. & Kimura, H., 01-11-2011, In : Cytokine. 56, 2, p. 180-187 8 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Increased levels of pregnancy-associated plasma protein-A2 in the serum of pre-eclamptic patients

Nishizawa, H., Pryor-Koishi, K., Suzuki, M., Kato, T., Kogo, H., Sekiya, T., Kurahashi, H. & Udagawa, Y., 01-12-2008, In : Molecular Human Reproduction. 14, 10, p. 595-602 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Increased levels of soluble corin in pre-eclampsia and fetal growth restriction

Miyazaki, J., Nishizawa, H., Kambayashi, A., Ito, M., Noda, Y., Terasawa, S., Kato, T., Miyamura, H., Shiogama, K., Sekiya, T., Kurahashi, H. & Fujii, T., 01-12-2016, In : Placenta. 48, p. 20-25 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Increased lung uptake of iodine-123-MIBG in diabetics with sympathetic nervous dysfunction

Murashima, S., Takeda, K., Matsumura, K., Yamakado, K., Sakuma, H., Kitano, T., Nakagawa, T., Ichihara, T., Yamakado, T. & Murata, K., 02-1998, In : Journal of Nuclear Medicine. 39, 2, p. 334-338 5 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Increased non-Gaussianity of heart rate variability predicts cardiac mortality after an acute myocardial infarction

Hayano, J., Kiyono, K., Struzik, Z. R., Yamamoto, Y., Watanabe, E., Stein, P. K., Watkins, L. L., Blumenthal, J. A. & Carney, R. M., 2011, In : Frontiers in Physiology. 2 SEP, Article 65.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Increased number of CpG island hypermethylation in tumor suppressor genes of non-neoplastic gastric mucosa correlates with higher risk of gastric cancer

Tahara, T., Shibata, T., Nakamura, M., Yamashita, H., Yoshioka, D., Okubo, M., Yonemura, J., Maeda, Y., Maruyama, N., Kamano, T., Kamiya, Y., Fujita, H., Nakagawa, Y., Nagasaka, M., Iwata, M., Hirata, I. & Arisawa, T., 01-04-2010, In : Digestion. 82, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Increased number of methylated CpG islands correlates with Helicobacter pylori infection, histological and serological severity of chronic gastritis

Tahara, T., Arisawa, T., Shibata, T., Nakamura, M., Yoshioka, D., Okubo, M., Maruyama, N., Kamano, T., Kamiya, Y., Fujita, H., Nakagawa, Y., Nagasaka, M., Iwata, M., Takahama, K., Watanabe, M., Yamashita, H. & Hirata, I., 01-06-2009, In : European Journal of Gastroenterology and Hepatology. 21, 6, p. 613-619 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids

Kanemitsu, Y., Matsumoto, H., Izuhara, K., Tohda, Y., Kita, H., Horiguchi, T., Kuwabara, K., Tomii, K., Otsuka, K., Fujimura, M., Ohkura, N., Tomita, K., Yokoyama, A., Ohnishi, H., Nakano, Y., Oguma, T., Hozawa, S., Nagasaki, T., Ito, I., Oguma, T. & 11 others, Inoue, H., Tajiri, T., Iwata, T., Izuhara, Y., Ono, J., Ohta, S., Tamari, M., Hirota, T., Yokoyama, T., Niimi, A. & Mishima, M., 08-2013, In : Journal of Allergy and Clinical Immunology. 132, 2, p. 305-312.e3

Research output: Contribution to journalArticle

137 Citations (Scopus)

Increased protein kinase A type Iα regulatory subunit expression in parathyroid gland adenomas of patients with primary hyperparathyroidism

Hibi, Y., Kambe, F., Imai, T., Ogawa, K., Shimizu, Y., Shibata, M., Kagawa, C., Mizuno, Y., Ito, A. & Iwase, K., 11-03-2013, In : endocrine journal. 60, 2, p. 215-223 9 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Increased Serological Response Against Human Herpesvirus 6A Is Associated With Risk for Multiple Sclerosis

Engdahl, E., Gustafsson, R., Huang, J., Biström, M., Lima Bomfim, I., Stridh, P., Khademi, M., Brenner, N., Butt, J., Michel, A., Jons, D., Hortlund, M., Alonso-Magdalena, L., Hedström, A. K., Flamand, L., Ihira, M., Yoshikawa, T., Andersen, O., Hillert, J., Alfredsson, L. & 5 others, Waterboer, T., Sundström, P., Olsson, T., Kockum, I. & Fogdell-Hahn, A., 26-11-2019, In : Frontiers in Immunology. 10, 2715.

Research output: Contribution to journalArticle

Open Access

Increased serum levels of Nε-(hexanoyl)lysine, a new marker of oxidative stress, in systemic sclerosis

Shimizu, K., Ogawa, F., Akiyama, Y., Muroi, E., Yoshizaki, A., Iwata, Y., Komura, K., Bae, S. & Sato, S., 11-2008, In : Journal of Rheumatology. 35, 11, p. 2214-2219 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Increased serum pentraxin 3 in patients with systemic sclerosis

Iwata, Y., Yoshizaki, A., Ogawa, F., Komura, K., Hara, T., Muroi, E., Takenaka, M., Shimizu, K., Hasegawa, M., Fujimoto, M., Takehara, K. & Sato, S., 05-2009, In : Journal of Rheumatology. 36, 5, p. 976-983 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Increased serum soluble OX40 in patients with systemic sclerosis

Komura, K., Yoshizaki, A., Kodera, M., Iwata, Y., Ogawa, F., Shimizu, K., Wayaku, T., Yukami, T., Murata, M., Hasegawa, M., Fujimoto, M., Takehara, K. & Sato, S., 12-2008, In : Journal of Rheumatology. 35, 12, p. 2359-2362 4 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Increased sorbitol levels in the hypertrophic ligamentum flavum of diabetic patients with lumbar spinal canal stenosis

Luo, J., Huang, L., Chen, Z., Zeng, Z., Miyamoto, T., Wu, H., Zhang, Z., Pan, Z., Fujita, N., Hikata, T., Iwanami, A., Tsuji, T., Ishii, K., Nakamura, M., Matsumoto, M., Watanabe, K. & Cao, K., 05-2017, In : Journal of Orthopaedic Research. 35, 5, p. 1058-1066 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Increased SPHK2 Transcription of Human Colon Cancer Cells in Serum-Depleted Culture: The Involvement of CREB Transcription Factor

Mizutani, N., Omori, Y., Tanaka, K., Ito, H., Takagi, A., Kojima, T., Nakatochi, M., Ogiso, H., Kawamoto, Y., Nakamura, M., Suzuki, M., Kyogashima, M., Tamiya-Koizumi, K., Nozawa, Y. & Murate, T., 01-10-2015, In : Journal of Cellular Biochemistry. 116, 10, p. 2227-2238 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Increased T-cell responses to Epstein-Barr virus with high viral load in patients with Epstein-Barr virus-positive diffuse large B-cell lymphoma

Morishima, S., Nakamura, S., Yamamoto, K., Miyauchi, H., Kagami, Y., Kinoshita, T., Onoda, H., Yatabe, Y., Ito, M., Miyamura, K., Nagai, H., Moritani, S., Sugiura, I., Tsushita, K., Mihara, H., Ohbayashi, K., Iba, S., Emi, N., Okamoto, M., Iwata, S. & 3 others, Kimura, H., Kuzushima, K. & Morishima, Y., 01-04-2015, In : Leukemia and Lymphoma. 56, 4, p. 1072-1078 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Increased urethral resistance by periurethral injection of low serum cultured adipose-derived mesenchymal stromal cells in rats

Watanabe, T., Maruyama, S., Yamamoto, T., Kamo, I., Yasuda, K., Saka, Y., Ozaki, T., Yuzawa, Y., Matsuo, S. & Gotoh, M., 01-09-2011, In : International Journal of Urology. 18, 9, p. 659-666 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Increased Urinary Neutrophil Gelatinase Associated Lipocalin Levels in a Rat Model of Upper Urinary Tract Infection

Ichino, M., Kuroyanagi, Y., Kusaka, M., Mori, T., Ishikawa, K., Shiroki, R., Kurahashi, H. & Hoshinaga, K., 01-05-2009, In : Journal of Urology. 181, 5, p. 2326-2331 6 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Increased urinary phosphate excretion in pseudohypoparathyroidism type II with long-term treatment with phosphodiesterase inhibitor

Mano, T., Uchimura, K., Hayashi, R., Kobahashi, T., Fujiwara, K., Makino, M., Kakizawa, H., Nagata, M., Nakai, A., Wada, M., Nagasaka, A. & Itoh, M., 01-01-1999, In : Hormone and Metabolic Research. 31, 11, p. 602-605 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Increase in direct social care costs of Alzheimer's disease in Japan depending on dementia severity

Takechi, H., Kokuryu, A., Kuzuya, A. & Matsunaga, S., 01-10-2019, In : Geriatrics and Gerontology International. 19, 10, p. 1023-1029 7 p.

Research output: Contribution to journalArticle

Increase in electrocardiographic R-waves after revascularization in patients with acute myocardial infarction

Isobe, S., Takada, Y., Ando, A., Ohshima, S., Yamada, K., Nanasato, M., Unno, K., Ogawa, T., Kondo, T., Izawa, H., Inden, Y., Hirai, M. & Murohara, T., 08-11-2006, In : Circulation Journal. 70, 11, p. 1385-1391 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis

Kawagishi-Hotta, M., Hasegawa, S., Igarashi, T., Date, Y., Ishii, Y., Inoue, Y., Hasebe, Y., Yamada, T., Arima, M., Iwata, Y., Kobayashi, T., Nakata, S., Sugiura, K. & Akamatsu, H., 12-2019, In : Regenerative Therapy. 11, p. 324-330 7 p.

Research output: Contribution to journalArticle

Open Access

Increasing and decreasing phases of ferritin and hemosiderin iron determined by serum ferritin kinetics

Saito, H., Hayashi, H., Tomita, A., Ohashi, H., Maeda, H. & Naoe, T., 2013, In : Nagoya journal of medical science. 75, 3-4, p. 213-223 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Increment of the amplitude of human photopic ERG during light adaptation

Miyake, Y., Horiguchi, M. & Yagasaki, K., 01-08-1986, In : Nippon Ganka Gakkai zasshi. 90, 8, p. 1102-1109 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

IncX2 and IncX1-X2 hybrid plasmids coexisting in a FosA6-producing Escherichia coli strain

Guo, Q., Su, J., McElheny, C. L., Stoesser, N., Doi, Y. & Wang, M., 07-2017, In : Antimicrobial agents and chemotherapy. 61, 7, e00536-17.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Independent association of liver fat accumulation with insulin resistance

Yatsuya, H., Nihashi, T., Li, Y., Hotta, Y., Matsushita, K., Muramatsu, T., Otsuka, R., Matsunaga, M., Yamashita, K., Wang, C., Uemura, M., Harada, A., Fukatsu, H., Toyoshima, H., Aoyama, A. & Tamakoshi, K., 01-01-2014, In : Obesity Research and Clinical Practice. 8, 4, p. e350-e355

Research output: Contribution to journalArticle

11 Citations (Scopus)

Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment

Trampush, J. W., Lencz, T., Knowles, E., Davies, G., Guha, S., Pe'er, I., Liewald, D. C., Starr, J. M., Djurovic, S., Melle, I., Sundet, K., Christoforou, A., Reinvang, I., Mukherjee, S., Derosse, P., Lundervold, A., Steen, V. M., John, M., Espeseth, T., Räikkönen, K. & 33 others, Widen, E., Palotie, A., Eriksson, J. G., Giegling, I., Konte, B., Ikeda, M., Roussos, P., Giakoumaki, S., Burdick, K. E., Payton, A., Ollier, W., Horan, M., Scult, M., Dickinson, D., Straub, R. E., Donohoe, G., Morris, D., Corvin, A., Gill, M., Hariri, A., Weinberger, D. R., Pendleton, N., Iwata, N., Darvasi, A., Bitsios, P., Rujescu, D., Lahti, J., Le Hellard, S., Keller, M. C., Andreassen, O. A., Deary, I. J., Glahn, D. C. & Malhotra, A. K., 01-07-2015, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 168, 5, p. 363-373 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Independent strong association of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe mucosal involvement

Ueta, M., Kaniwa, N., Sotozono, C., Tokunaga, K., Saito, Y., Sawai, H., Miyadera, H., Sugiyama, E., Maekawa, K., Nakamura, R., Nagato, M., Aihara, M., Matsunaga, K., Takahashi, Y., Furuya, H., Muramatsu, M., Ikezawa, Z. & Kinoshita, S., 30-04-2014, In : Scientific reports. 4, 4862.

Research output: Contribution to journalArticle

Open Access
42 Citations (Scopus)

Indication of cognitive change and associated risk factor after thoracic surgery in the elderly: A pilot study

Kulason, K., Nouchi, R., Hoshikawa, Y., Noda, M., Okada, Y. & Kawashima, R., 05-12-2017, In : Frontiers in Aging Neuroscience. 9, DEC, 396.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Indigo naturalis is effective even in treatment-refractory patients with ulcerative colitis: a post hoc analysis from the INDIGO study

For the INDIGO Study Group, 01-02-2020, In : Journal of Gastroenterology. 55, 2, p. 169-180 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Individual and joint impact of family history and Helicobacter pylori infection on the risk of stomach cancer: A nested case-control study

Yatsuya, H., Toyoshima, H., Tamakoshi, A., Kikuchi, S., Tamakoshi, K., Kondo, T., Mizoue, T., Tokui, N., Hoshiyama, Y., Sakata, K., Hayakawa, N. & Yoshimura, T., 31-08-2004, In : British Journal of Cancer. 91, 5, p. 929-934 6 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Individual clinically diagnosed with CHARGE syndrome but with a mutation in KMT2D, a gene associated with Kabuki syndrome: A case report

Sakata, S., Okada, S., Aoyama, K., Hara, K., Tani, C., Kagawa, R., Utsunomiya-Nakamura, A., Miyagawa, S., Ogata, T., Mizuno, H. & Kobayashi, M., 11-12-2017, In : Frontiers in Genetics. 8, DEC, 210.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Individual-dependent effects of pharyngeal electrical stimulation on swallowing in healthy humans

Tsukano, H., Taniguchi, H., Hori, K., Tsujimura, T., Nakamura, Y. & Inoue, M., 15-05-2012, In : Physiology and Behavior. 106, 2, p. 218-223 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Individual risk alleles of susceptibility to schizophrenia are associated with poor clinical and social outcomes

Sakamoto, S., Takaki, M., Okahisa, Y., Mizuki, Y., Inagaki, M., Ujike, H., Mitsuhashi, T., Takao, S., Ikeda, M., Uchitomi, Y., Iwata, N. & Yamada, N., 01-04-2016, In : Journal of Human Genetics. 61, 4, p. 329-334 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Indoxyl sulfate, a uremic toxin, and carotid intima-media thickness in patients with coronary artery disease

Sato, B., Yoshikawa, D., Ishii, H., Kikuchi, R., Arima, T., Takeshita, K., Inoue, Y., Suzuki, S., Tanaka, M., Kumagai, S., Matsumoto, M., Hayashi, M., Ando, H., Amano, T., Matsubara, T., Niwa, T. & Murohara, T., 20-02-2013, In : International Journal of Cardiology. 163, 2, p. 214-216 3 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Induced miR-31 by 5-fluorouracil exposure contributes to the resistance in colorectal tumors

Nakagawa, Y., Kuranaga, Y., Tahara, T., Yamashita, H., Shibata, T., Nagasaka, M., Funasaka, K., Ohmiya, N. & Akao, Y., 01-01-2019, In : Cancer science. 110, 8, p. 2540-2548 9 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Induced pluripotent stem cell-derived melanocyte precursor cells undergoing differentiation into melanocytes

Hosaka, C., Kunisada, M., Koyanagi-Aoi, M., Masaki, T., Takemori, C., Taniguchi-Ikeda, M., Aoi, T. & Nishigori, C., 01-01-2019, In : Pigment Cell and Melanoma Research. 32, 5, p. 623-633 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Induction and characterization of minor histocompatibility antigens. Specific primary cytotoxic T lymphocyte responses in vitro

Ando, K. I., Nakashima, I., Nagase, F., Isobe, K. I., Kawashima, K., Hasegawa, Y., Yoshida, T., Iwamoto, T., Hasegawa, T., Muro, Y. & Ohashi, M., 1988, In : Journal of Immunology. 140, 3, p. 723-729 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Induction of cell-cycle arrest and apoptosis by a novel retinobenzoic- acid derivative, TAC-101, in human pancreatic-cancer cells

Fujimoto, K., Hosotani, R., Doi, R., Wada, M., Lee, J. U., Koshiba, T., Miyamoto, Y., Tsuji, S., Nakajima, S. & Imamura, M., 10-05-1999, In : International Journal of Cancer. 81, 4, p. 637-644 8 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Induction of DC-STAMP by alternative activation and downstream signaling mechanisms

Yagi, M., Ninomiya, K., Fujita, N., Suzuki, T., Iwasaki, R., Morita, K., Hosogane, N., Matsuo, K., Toyama, Y., Suda, T. & Miyamoto, T., 01-07-2007, In : Journal of Bone and Mineral Research. 22, 7, p. 992-1001 10 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

Induction of Epstein-Barr virus oncoprotein LMP1 by transcription factors AP-2 and early B cell factor

Murata, T., Noda, C., Narita, Y., Watanabe, T., Yoshida, M., Ashio, K., Sato, Y., Goshima, F., Kanda, T., Yoshiyama, H., Tsurumi, T. & Kimura, H., 01-04-2016, In : Journal of Virology. 90, 8, p. 3873-3889 17 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Induction of high-grade anti-tumor immunity by use of a recombinant H-2Kb/avian erythroblastosis virus erbB gene transfectant

Ding, L. N., Isobe, K. I., Yoshida, T., Kawashima, K. & Nakashima, I., 03-1990, In : Cancer Immunology Immunotherapy. 31, 2, p. 115-120 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Induction of HLA-B*40:02-restricted T cells possessing cytotoxic and suppressive functions against haematopoietic progenitor cells from a patient with severe aplastic anaemia

Inaguma, Y., Akatsuka, Y., Hosokawa, K., Maruyama, H., Okamoto, A., Katagiri, T., Shiraishi, K., Murayama, Y., Tsuzuki-Iba, S., Mizutani, Y., Nishii, C., Yamamoto, N., Demachi-Okamura, A., Kuzushima, K., Ogawa, S., Emi, N. & Nakao, S., 01-01-2016, In : British Journal of Haematology. 172, 1, p. 131-134 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Induction of tyrosine phosphorylation in human B lineage cells by crosslinking MB-1 molecule of B cell receptor-related heterodimer complex

Kuwahara, K., Igarashi, H., Kawai, T., Ichigi, Y., Muraguchi, A., Mason, D. Y., Kimoto, M., Inui, S. & Sakaguchi, N., 30-12-1993, In : Biochemical and Biophysical Research Communications. 197, 3, p. 1563-1569 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Infection with Pasteurella multocida after a cat scratch

Nakagawa, M., Nagashima, C., Akita, H., Yagami, A. & Matsunaga, K., 01-04-2005, In : Skin Research. 4, 2, p. 172-174 3 p.

Research output: Contribution to journalArticle

Infection with TT virus, a novel transfusion-transmissible DNA virus, in haemophiliacs and in blood products

Yokozaki, S., Toyoda, H., Nakano, I., Katano, Y., Ebata, M., Fukuda, Y., Takamatsu, J., Satto, H. & Hayakawa, T., 1999, In : British Journal of Haematology. 105, 4, p. 1114-1119 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)