• 2307 Citations
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20052019
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Research Output 2005 2019

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Article
2011
47 Citations (Scopus)
Psychiatry
Social Isolation
Mothers
Mood Disorders
Schizophrenia
2010
39 Citations (Scopus)

Galantamine ameliorates the impairment of recognition memory in mice repeatedly treated with methamphetamine: Involvement of allosteric potentiation of nicotinic acetylcholine receptors and dopaminergic-ERK1/2 systems

Noda, Y., Mouri, A., Ando, Y., Waki, Y., Yamada, S. N., Yoshimi, A., Yamada, K., Ozaki, N., Wang, D. & Nabeshima, T., 01-11-2010, In : International Journal of Neuropsychopharmacology. 13, 10, p. 1343-1354 12 p.

Research output: Contribution to journalArticle

Galantamine
Mitogen-Activated Protein Kinase 3
Methamphetamine
Mitogen-Activated Protein Kinase 1
Nicotinic Receptors
65 Citations (Scopus)

Identification of Novel Candidate Genes for Treatment Response to Risperidone and Susceptibility for Schizophrenia: Integrated Analysis Among Pharmacogenomics, Mouse Expression, and Genetic Case-Control Association Approaches

Ikeda, M., Tomita, Y., Mouri, A., Koga, M., Okochi, T., Yoshimura, R., Yamanouchi, Y., Kinoshita, Y., Hashimoto, R., Williams, H. J., Takeda, M., Nakamura, J., Nabeshima, T., Owen, M. J., O'Donovan, M. C., Honda, H., Arinami, T., Ozaki, N. & Iwata, N., 01-02-2010, In : Biological Psychiatry. 67, 3, p. 263-269 7 p.

Research output: Contribution to journalArticle

Risperidone
Genetic Association Studies
Schizophrenia
Single Nucleotide Polymorphism
Genes
13 Citations (Scopus)

Prenatal exposure to phencyclidine produces abnormal behaviour and NMDA receptor expression in postpubertal mice

Lu, L., Mamiya, T., Lu, P., Toriumi, K., Mouri, A., Hiramatsu, M., Kim, H. C., Zou, L. B., Nagai, T. & Nabeshima, T., 01-08-2010, In : International Journal of Neuropsychopharmacology. 13, 7, p. 877-889 13 p.

Research output: Contribution to journalArticle

Phencyclidine
Schizophrenia
Locomotion
Aspartic Acid
Antipsychotic Agents
54 Citations (Scopus)

Silibinin attenuates cognitive deficits and decreases of dopamine and serotonin induced by repeated methamphetamine treatment

Lu, P., Mamiya, T., Lu, L., Mouri, A., Niwa, M., Kim, H. C., Zou, L. B., Nagai, T., Yamada, K., Ikejima, T. & Nabeshima, T., 05-03-2010, In : Behavioural Brain Research. 207, 2, p. 387-393 7 p.

Research output: Contribution to journalArticle

Methamphetamine
Dopamine
Serotonin
Prefrontal Cortex
Hippocampus
16 Citations (Scopus)

The role of cyclophilin D in learning and memory

Mouri, A., Noda, Y., Shimizu, S., Tsujimoto, Y. & Nabeshima, T., 01-02-2010, In : Hippocampus. 20, 2, p. 293-304 12 p.

Research output: Contribution to journalArticle

Learning
Aptitude
Hippocampus
cyclophilin D
Short-Term Memory
2009
50 Citations (Scopus)

Matrix metalloprotease-9 inhibition improves amyloid β-mediated cognitive impairment and neurotoxicity in mice

Mizoguchi, H., Takuma, K., Fukuzaki, E., Ibi, D., Someya, E., Akazawa, K. H., Alkam, T., Tsunekawa, H., Mouri, A., Noda, Y., Nabeshima, T. & Yamada, K., 01-10-2009, In : Journal of Pharmacology and Experimental Therapeutics. 331, 1, p. 14-22 9 p.

Research output: Contribution to journalArticle

Metalloproteases
Amyloid
Hippocampus
Neuroglia
Inhibition (Psychology)
54 Citations (Scopus)

Silibinin attenuates amyloid β25-35 peptide-induced memory impairments: Implication of inducible nitric-oxide synthase and tumor necrosis factor-α in mice

Lu, P., Mamiya, T., Lu, L. L., Mouri, A., Niwa, M., Hiramatsu, M., Zou, L. B., Nagai, T., Ikejima, T. & Nabeshima, T., 01-10-2009, In : Journal of Pharmacology and Experimental Therapeutics. 331, 1, p. 319-326 8 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type II
Amyloid
Tumor Necrosis Factor-alpha
Peptides
Amygdala
129 Citations (Scopus)

Silibinin prevents amyloid b peptide-induced memory impairment and oxidative stress in mice

Lu, P., Mamiya, T., Lu, L. L., Mouri, A., Zou, L. B., Nagai, T., Hiramatsu, M., Ikejima, T. & Nabeshima, T., 29-10-2009, In : British Journal of Pharmacology. 157, 7, p. 1270-1277 8 p.

Research output: Contribution to journalArticle

Amyloid
Oxidative Stress
Peptides
Milk Thistle
Malondialdehyde
24 Citations (Scopus)

The long-lasting effects of cross-fostering on the emotional behavior in ICR mice

Lu, L., Mamiya, T., Lu, P., Niwa, M., Mouri, A., Zou, L. B., Nagai, T., Hiramatsu, M. & Nabeshima, T., 02-03-2009, In : Behavioural Brain Research. 198, 1, p. 172-178 7 p.

Research output: Contribution to journalArticle

Inbred ICR Mouse
Foster Home Care
Psychological Stress
Serotonin
Interpersonal Relations
2008
19 Citations (Scopus)

An association between serotonin receptor 3B gene (HTR3B) and treatment-resistant schizophrenia (TRS) in a Japanese population.

Ji, X., Takahashi, N., Branko, A., Ishihara, R., Nagai, T., Mouri, A., Saito, S., Maeno, N., Inada, T. & Ozaki, N., 03-2008, In : Nagoya journal of medical science. 70, 1-2, p. 11-17 7 p.

Research output: Contribution to journalArticle

Serotonin Receptors
Schizophrenia
Alleles
Population
Genes
52 Citations (Scopus)

Synergistic effects of selegiline and donepezil on cognitive impairment induced by amyloid beta (25-35)

Tsunekawa, H., Noda, Y., Mouri, A., Yoneda, F. & Nabeshima, T., 19-07-2008, In : Behavioural Brain Research. 190, 2, p. 224-232 9 p.

Research output: Contribution to journalArticle

Selegiline
Cognition
Fear
Alzheimer Disease
Learning
2007
1 Citation (Scopus)

Evaluation of latent learning in a water-finding test by using model animals

Mouri, A., Noda, Y. & Nabeshima, T., 01-12-2007, In : Folia Pharmacologica Japonica. 130, 2, p. 141-146 6 p.

Research output: Contribution to journalArticle

Animal Models
Learning
Water
59 Citations (Scopus)
Phencyclidine
N-Methylaspartate
Prefrontal Cortex
Synaptic Transmission
Glutamic Acid
68 Citations (Scopus)

Involvement of a dysfunctional dopamine-D1/N-methyl-D-aspartate-NR1 and Ca2+/calmodulin-dependent protein kinase II pathway in the impairment of latent learning in a model of schizophrenia induced by phencyclidine

Mouri, A., Noda, Y., Noda, A., Nakamura, T., Tokura, T., Yura, Y., Nitta, A., Furukawa, H. & Nabeshima, T., 01-06-2007, In : Molecular Pharmacology. 71, 6, p. 1598-1609 12 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Phencyclidine
N-Methylaspartate
Prefrontal Cortex
Dopamine
118 Citations (Scopus)

Oral vaccination with a viral vector containing Aβ cDNA attenuates age-related Aβ accumulation and memory deficits without causing inflammation in a mouse Alzheimer model

Mouri, A., Noda, Y., Hara, H., Mizoguchi, H., Tabira, T. & Nabeshima, T., 01-07-2007, In : FASEB Journal. 21, 9, p. 2135-2148 14 p.

Research output: Contribution to journalArticle

oral vaccination
Memory Disorders
Infiltration
Alzheimer Disease
Vaccination
12 Citations (Scopus)

Processing of nerve growth factor: The role of basic amino acid clusters in the pro-region

Mouri, A., Nomoto, H. & Furukawa, S., 23-02-2007, In : Biochemical and Biophysical Research Communications. 353, 4, p. 1056-1062 7 p.

Research output: Contribution to journalArticle

Basic Amino Acids
Nerve Growth Factors
Nerve Growth Factor
Processing
Furin
17 Citations (Scopus)

Pro-region of neurotrophins determines the processing efficiency

Nomoto, H., Takaiwa, M., Mouri, A. & Furukawa, S., 18-05-2007, In : Biochemical and Biophysical Research Communications. 356, 4, p. 919-924 6 p.

Research output: Contribution to journalArticle

Nerve Growth Factors
Processing
Brain-Derived Neurotrophic Factor
PC12 Cells
Nerve Growth Factor
61 Citations (Scopus)

Reduction of methamphetamine-induced sensitization and reward in matrix metalloproteinase-2 and -9-deficient mice

Mizoguchi, H., Yamada, K., Niwa, M., Mouri, A., Mizuno, T., Noda, Y., Nitta, A., Itohara, S., Banno, Y. & Nabeshima, T., 01-03-2007, In : Journal of Neurochemistry. 100, 6, p. 1579-1588 10 p.

Research output: Contribution to journalArticle

Methamphetamine
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9
Reward
Dopamine
50 Citations (Scopus)

Role of matrix metalloproteinase and tissue inhibitor of MMP in methamphetamine-induced behavioral sensitization and reward: Implications for dopamine receptor down-regulation and dopamine release

Mizoguchi, H., Yamada, K., Mouri, A., Niwa, M., Mizuno, T., Noda, Y., Nitta, A., Itohara, S., Banno, Y. & Nabeshima, T., 01-09-2007, In : Journal of Neurochemistry. 102, 5, p. 1548-1560 13 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinases
Matrix Metalloproteinase Inhibitors
Methamphetamine
Dopamine Receptors
Matrix Metalloproteinases
85 Citations (Scopus)

The allosteric potentiation of nicotinic acetylcholine receptors by galantamine ameliorates the cognitive dysfunction in beta amyloid 25-35 I.c.v.-injected mice: Involvement of dopaminergic systems

Wang, D., Noda, Y., Zhou, Y., Mouri, A., Mizoguchi, H., Nitta, A., Chen, W. & Nabeshima, T., 01-06-2007, In : Neuropsychopharmacology. 32, 6, p. 1261-1271 11 p.

Research output: Contribution to journalArticle

Galantamine
Nicotinic Receptors
Mecamylamine
Dopamine
Synaptic Transmission
2006
36 Citations (Scopus)

An analog of a dipeptide-like structure of FK506 increases glial cell line-derived neurotrophic factor expression through cAMP response element-binding Protein activated by heat shock protein 90/Akt signaling pathway

Cen, X., Nitta, A., Ohya, S., Zhao, Y., Ozawa, N., Mouri, A., Ibi, D., Wang, L., Suzuki, M., Saito, K., Ito, Y., Kawagoe, T., Noda, Y., Ito, Y., Furukawa, S. & Nabeshima, T., 22-03-2006, In : Journal of Neuroscience. 26, 12, p. 3335-3344 10 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
HSP90 Heat-Shock Proteins
Cyclic AMP Response Element-Binding Protein
Isoleucine
Dipeptides
60 Citations (Scopus)

Effects of a novel cognitive enhancer, spiro[imidazo-[1,2-a]pyridine-3,2- indan]-2(3H)-one (ZSET1446), on learning impairments induced by amyloid-β1-40 in the rat

Yamaguchi, Y., Miyashita, H., Tsunekawa, H., Mouri, A., Kim, H. C., Saito, K., Matsuno, T., Kawashima, S. & Nabeshima, T., 01-06-2006, In : Journal of Pharmacology and Experimental Therapeutics. 317, 3, p. 1079-1087 9 p.

Research output: Contribution to journalArticle

Nootropic Agents
Amyloid
Learning
Intraventricular Infusions
Scopolamine Hydrobromide
3 Citations (Scopus)

Genetically modified mice harboring mitochondrial DNA defects show aberrant cyclic change in wheel-running activity, which is improved by lithium

Kasahara, T., Kubota, M., Miyauchi, T., Noda, Y., Mouri, A., Nabeshima, T. & Kato, T., 01-06-2006, In : Molecular Psychiatry. 11, 6, 1 p.

Research output: Contribution to journalArticle

Mitochondrial DNA
Lithium
Running
33 Citations (Scopus)

Inhibition of neprilysin by infusion of thiorphan into the hippocampus causes an accumulation of amyloid β and impairment of learning and memory

Zou, L. B., Mouri, A., Iwata, N., Saido, T. C., Wang, D., Wang, M. W., Mizoguchi, H., Noda, Y. & Nabeshima, T., 01-04-2006, In : Journal of Pharmacology and Experimental Therapeutics. 317, 1, p. 334-340 7 p.

Research output: Contribution to journalArticle

Thiorphan
Neprilysin
Amyloid
Hippocampus
Learning
35 Citations (Scopus)

Inhibition of neprilysin by thiorphan (i.c.v.) causes an accumulation of amyloid β and impairment of learning and memory

Mouri, A., Zou, L. B., Iwata, N., Saido, T. C., Wang, D., Wang, M. W., Noda, Y. & Nabeshima, T., 15-03-2006, In : Behavioural Brain Research. 168, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

Thiorphan
Neprilysin
Amyloid
Learning
Cerebral Ventricles
107 Citations (Scopus)

Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes

Kasahara, T., Kubota, M., Miyauchi, T., Noda, Y., Mouri, A., Nabeshima, T. & Kato, T., 01-06-2006, In : Molecular Psychiatry. 11, 6, p. 577-593 17 p.

Research output: Contribution to journalArticle

Mood Disorders
Mitochondrial DNA
Bipolar Disorder
Phenotype
Neurons
136 Citations (Scopus)

Neprilysin-sensitive synapse-associated amyloid-β peptide oligomers impair neuronal plasticity and cognitive function

Huang, S. M., Mouri, A., Kokubo, H., Nakajima, R., Suemoto, T., Higuchi, M., Staufenbiel, M., Noda, Y., Yamaguchi, H., Nabeshima, T., Saido, T. C. & Iwata, N., 30-06-2006, In : Journal of Biological Chemistry. 281, 26, p. 17941-17951 11 p.

Research output: Contribution to journalArticle

Neprilysin
Neuronal Plasticity
Oligomers
Amyloid
Synapses
2005
40 Citations (Scopus)

Long-lasting impairment of associative learning is correlated with a dysfunction of N-methyl-D-aspartate-extracellular signaling-regulated kinase signaling in mice after withdrawal from repeated administration of phencyclidine

Enomoto, T., Noda, Y., Mouri, A., Shin, E. J., Wang, D., Murai, R., Hotta, K., Furukawa, H., Nitta, A., Kim, H. C. & Nabeshima, T., 01-12-2005, In : Molecular Pharmacology. 68, 6, p. 1765-1774 10 p.

Research output: Contribution to journalArticle

Phencyclidine
N-Methylaspartate
Phosphotransferases
Learning
Hippocampus