• 5852 Citations
  • 39 h-Index
1984 …2019

Research output per year

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Research Output

2019
Open Access
1 Citation (Scopus)

Component of splicing factor SF3b plays a key role in translational control of polyribosomes on the endoplasmic reticulum

Ueno, T., Taga, Y., Yoshimoto, R., Mayeda, A., Hattori, S. & Ogawa-Goto, K., 07-05-2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 19, p. 9340-9349 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2018

HMGA1a induces alternative splicing of estrogen receptor alpha in MCF-7 human breast cancer cells

Ohe, K., Miyajima, S., Abe, I., Tanaka, T., Hamaguchi, Y., Harada, Y., Horita, Y., Beppu, Y., Ito, F., Yamasaki, T., Terai, H., Mori, M., Murata, Y., Tanabe, M., Ashida, K., Kobayashi, K., Enjoji, M., Yanase, T., Harada, N., Utsumi, T. & 1 others, Mayeda, A., 09-2018, In : Journal of Steroid Biochemistry and Molecular Biology. 182, p. 21-26 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

HMGA1a induces alternative splicing of the estrogen receptor-alpha gene by trapping U1 snRNP to an upstream pseudo-5' splice site

Ohe, K., Miyajima, S., Tanaka, T., Hamaguchi, Y., Harada, Y., Horita, Y., Beppu, Y., Ito, F., Yamasaki, T., Terai, H., Mori, M., Murata, Y., Tanabe, M., Abe, I., Ashida, K., Kobayashi, K., Enjoji, M., Nomiyama, T., Yanase, T., Harada, N. & 2 others, Utsumi, T. & Mayeda, A., 08-06-2018, In : Frontiers in Molecular Biosciences. 5, JUN, 52.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1–RUNX1T1 leukemia with t(8;12;21)

Abe, A., Yamamoto, Y., Katsumi, A., Okamoto, A., Tokuda, M., Inaguma, Y., Yamamoto, K., Yanada, M., Kanie, T., Tomita, A., Akatsuka, Y., Okamoto, M., Kameyama, T., Mayeda, A. & Emi, N., 01-08-2018, In : International Journal of Hematology. 108, 2, p. 208-212 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
3 Citations (Scopus)
2017

Global analysis of pre-mRNA subcellular localization following splicing inhibition by spliceostatin A

Yoshimoto, R., Kaida, D., Furuno, M., Burroughs, A. M., Noma, S., Suzuki, H., Kawamura, Y., Hayashizaki, Y., Mayeda, A. & Yoshida, M., 01-2017, In : RNA. 23, 1, p. 47-57 11 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2016

Endogenous multiple exon skipping and back-splicing at the DMD mutation hotspot

Suzuki, H., Aoki, Y., Kameyama, T., Saito, T., Masuda, S., Tanihata, J., Nagata, T., Mayeda, A., Takeda, SI. & Tsukahara, T., 13-10-2016, In : International journal of molecular sciences. 17, 10, 1722.

Research output: Contribution to journalArticle

21 Citations (Scopus)

ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9

Abe, A., Yamamoto, Y., Iba, S., Kanie, T., Okamoto, A., Tokuda, M., Inaguma, Y., Yanada, M., Morishima, S., Mizuta, S., Akatsuka, Y., Okamoto, M., Kameyama, T., Mayeda, A. & Emi, N., 01-03-2016, In : Genes Chromosomes and Cancer. 55, 3, p. 242-250 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

MALAT1 long non-coding RNA in cancer

Yoshimoto, R., Mayeda, A., Yoshida, M. & Nakagawa, S., 01-01-2016, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1859, 1, p. 192-199 8 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)

The exon junction complex controls the efficient and faithful splicing of a subset of transcripts involved in mitotic cell-cycle progression

Fukumura, K., Wakabayashi, S., Kataoka, N., Sakamoto, H., Suzuki, Y., Nakai, K., Mayeda, A. & Inoue, K., 02-08-2016, In : International journal of molecular sciences. 17, 8, 1153.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2015

Identification and validation of evolutionarily conserved unusually short pre-mRNA introns in the human genome

Shimada, M. K., Sasaki-Haraguchi, N. & Mayeda, A., 07-05-2015, In : International journal of molecular sciences. 16, 5, p. 10376-10388 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

NUP214-RAC1 and RAC1-COL12A1 Fusion in Complex Variant Translocations Involving Chromosomes 6, 7 and 9 in an Acute Myeloid Leukemia Case with DEK-NUP214

Abe, A., Yamamoto, Y., Iba, S., Okamoto, A., Tokuda, M., Inaguma, Y., Yanada, M., Morishima, S., Kanie, T., Tsuzuki, M., Akatsuka, Y., Mizuta, S., Okamoto, M., Kameyama, T., Mayeda, A. & Emi, N., 01-12-2015, In : Cytogenetic and Genome Research. 146, 4, p. 279-284 6 p.

Research output: Contribution to journalArticle

2013

HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA

Rahman, M. A., Masuda, A., Ohe, K., Ito, M., Hutchinson, D. O., Mayeda, A., Engel, A. G. & Ohno, K., 25-10-2013, In : Scientific reports. 3, 2931.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Nested introns in an intron: Evidence of multi-step splicing in a large intron of the human dystrophin pre-mRNA

Suzuki, H., Kameyama, T., Ohe, K., Tsukahara, T. & Mayeda, A., 18-03-2013, In : FEBS Letters. 587, 6, p. 555-561 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2012

Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles

Miyagawa, R., Tano, K., Mizuno, R. I. E., Nakamura, Y. O., Ijiri, K., Rakwal, R., Shibato, J., Masuo, Y., Mayeda, A., Hirose, T. & Akimitsu, N., 01-04-2012, In : RNA. 18, 4, p. 738-751 14 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

In Vitro Splicing Assays

Mayeda, A. & Krainer, A. R., 02-02-2012, Alternative pre-mRNA Splicing: Theory and Protocols. Wiley-VCH, p. 320-329 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Mechanistic insights into human pre-mRNA splicing of human ultra-short introns: Potential unusual mechanism identifies G-rich introns

Sasaki-Haraguchi, N., Shimada, M. K., Taniguchi, I., Ohno, M. & Mayeda, A., 29-06-2012, In : Biochemical and Biophysical Research Communications. 423, 2, p. 289-294 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Re-splicing of mature mRNA in cancer cells promotes activation of distant weak alternative splice sites

Kameyama, T., Suzuki, H. & Mayeda, A., 01-09-2012, In : Nucleic Acids Research. 40, 16, p. 7896-7906 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2010
25 Citations (Scopus)

The expression of HMGA1a is increased in lymphoblastoid cell lines from schizophrenia patients

Morikawa, T., Manabe, T., Ito, Y., Yamada, S., Yoshimi, A., Nagai, T., Ozaki, N. & Mayeda, A., 01-05-2010, In : Neurochemistry International. 56, 6-7, p. 736-739 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2009

[Oncogenic HMGA1a protein causes sporadic Alzheimer's disease-associated aberrant splicing].

Mayeda, A., Manabe, T. & Ohe, K., 01-12-2009, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 54, 16 Suppl, p. 2245-2250 6 p.

Research output: Contribution to journalReview article

2007

HMGA1a: Sequence-specific RNA-binding factor causing sporadic Alzheimer's disease-linked exon skipping of presenilin-2 pre-mRNA

Manabe, T., Ohe, K., Katayama, T., Matsuzaki, S., Yanagita, T., Okuda, H., Bando, Y., Imaizumi, K., Reeves, R., Tohyama, M. & Mayeda, A., 01-10-2007, In : Genes to Cells. 12, 10, p. 1179-1191 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2006

Characterization of RNase R-digested cellular RNA source that consists of lariat and circular RNAs from pre-mRNA splicing

Suzuki, H., Zuo, Y., Wang, J., Zhang, M. Q., Malhotra, A. & Mayeda, A., 10-07-2006, In : Nucleic Acids Research. 34, 8, e63.

Research output: Contribution to journalArticle

240 Citations (Scopus)

Thr199 phosphorylation targets nucleophosmin to nuclear speckles and represses pre-mRNA processing

Tarapore, P., Shinmura, K., Suzuki, H., Tokuyama, Y., Kim, S. H., Mayeda, A. & Fukasawa, K., 23-01-2006, In : FEBS Letters. 580, 2, p. 399-409 11 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
2005

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation

Trembley, J. H., Tatsumi, S., Sakashita, E., Loyer, P., Slaughter, C. A., Suzuki, H., Endo, H., Kidd, V. J. & Mayeda, A., 01-02-2005, In : Molecular and Cellular Biology. 25, 4, p. 1446-1457 12 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2004

Erratum: Human RNPS1 and Its Associated Factors: A Versatile Alternative Pre-mRNA Splicing Regulator In Vivo (Molecular and Cellular Biology (2004) 24, 3 (1174-1187))

Sakashita, E., Tatsumi, S., Werner, D., Endo, H. & Mayeda, A., 01-04-2004, In : Molecular and Cellular Biology. 24, 7, 1 p.

Research output: Contribution to journalComment/debate

Human RNPS1 and Its Associated Factors: A Versatile Alternative Pre-mRNA Splicing Regulator in Vivo

Sakashita, E., Tatsumi, S., Werner, D., Endo, H. & Mayeda, A., 01-02-2004, In : Molecular and Cellular Biology. 24, 3, p. 1174-1187 14 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Tra2β, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA

Kondo, S., Yamamoto, N., Murakami, T., Okumura, M., Mayeda, A. & Imaizumi, K., 01-02-2004, In : Genes to Cells. 9, 2, p. 121-130 10 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)
2003

A novel rat orthologue and homologue for the Drosophila crooked neck gene in neural stem cells and their immediate descendants

Amada, N., Tezuka, T., Mayeda, A., Araki, K., Takei, N., Todokoro, K. & Nawa, H., 01-05-2003, In : Journal of Biochemistry. 133, 5, p. 615-623 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

CDK11 complexes promote pre-mRNA splicing

Hu, D., Mayeda, A., Trembley, J. H., Lahti, J. M. & Kidd, V. J., 07-03-2003, In : Journal of Biological Chemistry. 278, 10, p. 8623-8629 7 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)
32 Citations (Scopus)

Human Immunodeficiency Virus Type 1 hnRNP A/B-Dependent Exonic Splicing Silencer ESSV Antagonizes Binding of U2AF65 to Viral Polypyrimidine Tracts

Domsic, J. K., Wang, Y., Mayeda, A., Krainer, A. R. & Stoltzfus, C. M., 01-12-2003, In : Molecular and Cellular Biology. 23, 23, p. 8762-8772 11 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Induced HMGA 1a expression causes aberrant splicing a Presenilin-2 pre-mRNA in sporadic Alzhiemer's disease

Manabe, T., Katayama, T., Sato, N., Gomi, F., Hitomi, J., Yanagita, T., Kudo, T., Honda, A., Mori, Y., Matsuzaki, S., Imaizumi, K., Mayeda, A. & Tohyama, M., 01-06-2003, In : Cell Death and Differentiation. 10, 6, p. 698-708 11 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Pre-mRNA splicing: a source of a diversified gene expression network

Mayeda, A. & Suzuki, H., 03-2003, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 48, 4 Suppl, p. 404-413 10 p.

Research output: Contribution to journalReview article

2002

Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch

Hou, V. C., Lersch, R., Gee, S. L., Ponthier, J. L., Lo, A. J., Wu, M., Turck, C. W., Koury, M., Krainer, A. R., Mayeda, A. & Conboy, J. G., 15-11-2002, In : EMBO Journal. 21, 22, p. 6195-6204 10 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)
2001

Characterization of Two Evolutionarily Conserved, Alternatively Spliced Nuclear Phosphoproteins, NFAR-1 and -2, that Function in mRNA Processing and Interact with the Double-stranded RNA-dependent Protein Kinase, PKR

Saunders, L. R., Perkins, D. J., Balachandran, S., Michaels, R., Ford, R., Mayeda, A. & Barber, G. N., 24-08-2001, In : Journal of Biological Chemistry. 276, 34, p. 32300-32312 13 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins

Zhu, J., Mayeda, A. & Krainer, A. R., 01-01-2001, In : Molecular Cell. 8, 6, p. 1351-1361 11 p.

Research output: Contribution to journalArticle

267 Citations (Scopus)

RNA splicing at human immunodeficiency virus type 1 3′ splice site A2 is regulated by binding of hnRNP A/B proteins to an exonic splicing silencer element

Bilodeau, P. S., Domsic, J. K., Mayeda, A., Krainer, A. R. & Stoltzfus, C. M., 31-08-2001, In : Journal of Virology. 75, 18, p. 8487-8497 11 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)

Serine-Arginine (SR) Protein-like Factors That Antagonize Authentic SR Proteins and Regulate Alternative Splicing

Cowper, A. E., Cáceres, J. F., Mayeda, A. & Screaton, G. R., 28-12-2001, In : Journal of Biological Chemistry. 276, 52, p. 48908-48914 7 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

ZNF265 - A novel spliceosomal protein able to induce alternative splicing

Adams, D. J., Van Der Weyden, L., Mayeda, A., Stamm, S., Morris, B. J. & Rasko, J. E. J., 09-07-2001, In : Journal of Cell Biology. 154, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
2000

Mapping the SF2/ASF binding sites in the bovine growth hormone exonic splicing enhancer

Dirksen, W. P., Li, X., Mayeda, A., Krainer, A. R. & Rottman, F. M., 15-09-2000, In : Journal of Biological Chemistry. 275, 37, p. 29170-29177 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Selection of alternative 5' splice sites: Role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1

Eperon, I. C., Makarova, O. V., Mayeda, A., Munroe, S. H., Caceres, J. F., Hayward, D. G. & Krainer, A. R., 11-11-2000, In : Molecular and Cellular Biology. 20, 22, p. 8303-8318 16 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)
1999

Characterization of a SR protein from Trypanosoma brucei with homology to RNA-binding cis-splicing proteins

Ismaïli, N., Pérez-Morga, D., Walsh, P., Mayeda, A., Pays, A., Tebabi, P., Krainer, A. R. & Pays, E., 30-07-1999, In : Molecular and Biochemical Parasitology. 102, 1, p. 103-115 13 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Evidence for the function of an exonic splicing enhancer after the first catalytic step of pre-mRNA splicing

Chew, S. L., Liu, H. X., Mayeda, A. & Krainer, A. R., 14-09-1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 19, p. 10655-10660 6 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing

Caputi, M., Mayeda, A., Krainer, A. R. & Zahler, A. M., 15-07-1999, In : EMBO Journal. 18, 14, p. 4060-4067 8 p.

Research output: Contribution to journalArticle

217 Citations (Scopus)

Mammalian in vitro splicing assays.

Mayeda, A. & Krainer, A. R., 1999, In : Methods in molecular biology (Clifton, N.J.). 118, p. 315-321 7 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Preparation of HeLa cell nuclear and cytosolic S100 extracts for in vitro splicing.

Mayeda, A. & Krainer, A. R., 1999, In : Methods in molecular biology (Clifton, N.J.). 118, p. 309-314 6 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Purification and characterization of human RNPS1: A general activator of pre-mRNA splicing

Mayeda, A., Badolato, J., Kobayashi, R., Zhang, M. Q., Gardiner, E. M. & Krainer, A. R., 16-08-1999, In : EMBO Journal. 18, 16, p. 4560-4570 11 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)