• 764 Citations
  • 14 h-Index
19962019
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Fingerprint Dive into the research topics where Akira Nakashima is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Tyrosine 3-Monooxygenase Medicine & Life Sciences
Lipopolysaccharides Medicine & Life Sciences
Locus Coeruleus Medicine & Life Sciences
Dopamine Medicine & Life Sciences
GTP Cyclohydrolase Medicine & Life Sciences
PC12 Cells Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Risperidone Medicine & Life Sciences

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Research Output 1996 2019

1 Citation (Scopus)

Human tyrosine hydroxylase in Parkinson’s disease and in related disorders

Nagatsu, T., Nakashima, A., Ichinose, H. & Kobayashi, K., 01-04-2019, In : Journal of Neural Transmission. 126, 4, p. 397-409 13 p.

Research output: Contribution to journalReview article

Tyrosine 3-Monooxygenase
Parkinson Disease
Dopaminergic Neurons
Dopamine
Corpus Striatum

Identification by nano-LC-MS/MS of NT5DC2 as a protein binding to tyrosine hydroxylase: Down-regulation of NT5DC2 by siRNA increases catecholamine synthesis in PC12D cells

Nakashima, A., Yamaguchi, H., Kodani, Y., Kaneko, Y. S., Kawata, M., Nagasaki, H., Nagatsu, T. & Ota, A., 03-09-2019, In : Biochemical and Biophysical Research Communications. 516, 4, p. 1060-1065 6 p.

Research output: Contribution to journalArticle

Tyrosine 3-Monooxygenase
Protein Binding
Small Interfering RNA
Catecholamines
Down-Regulation
2 Citations (Scopus)

Proteasome-mediated degradation of tyrosine hydroxylase triggered by its phosphorylation: a new question as to the intracellular location at which the degradation occurs

Nakashima, A., Kodani, Y., Kaneko, Y. S., Nagasaki, H. & Ota, A., 01-01-2018, In : Journal of Neural Transmission. 125, 1, p. 9-15 7 p.

Research output: Contribution to journalReview article

Tyrosine 3-Monooxygenase
Proteasome Endopeptidase Complex
Phosphorylation
Nuclear Localization Signals
Cytoplasm
10 Citations (Scopus)

Inhibition of deubiquitinating activity of USP14 decreases tyrosine hydroxylase phosphorylated at Ser19 in PC12D cells

Nakashima, A., Ohnuma, S., Kodani, Y., Kaneko, Y. S., Nagasaki, H., Nagatsu, T. & Ota, A., 15-04-2016, In : Biochemical and Biophysical Research Communications. 472, 4, p. 598-602 5 p.

Research output: Contribution to journalArticle

Tyrosine 3-Monooxygenase
Proteasome Endopeptidase Complex
Phosphorylation
Molecules
Degradation
2 Citations (Scopus)

Aripiprazole increases NAD(P)H–quinone oxidoreductase-1 and heme oxygenase-1 in PC12 cells

Kaneko, Y. S., Takayanagi, T., Nagasaki, H., Kodani, Y., Nakashima, A., Mori, K., Suzuki, A., Itoh, M., Kondo, K., Nagatsu, T., Ota, M. & Ota, A., 01-06-2015, In : Journal of Neural Transmission. 122, 6, p. 757-772 16 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
PC12 Cells
NAD
Oxidoreductases
NADP