• 1510 Citations
  • 14 h-Index
20032019

Research output per year

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Research Output

  • 1510 Citations
  • 14 h-Index
  • 25 Article
  • 2 Review article
  • 1 Comment/debate
2019

Clustered DNA double-strand break formation and the repair pathway following heavy-ion irradiation

Hagiwara, Y., Oike, T., Niimi, A., Yamauchi, M., Sato, H., Limsirichaikul, S., Held, K. D., Nakano, T. & Shibata, A., 01-01-2019, In : Journal of Radiation Research. 60, 1, p. 69-79 11 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
2018

Analysis of programmed death-ligand 1 expression in primary normal human dermal fibroblasts after DNA damage

Hagiwara, Y., Sato, H., Permata, T. B. M., Niimi, A., Yamauchi, M., Oike, T., Nakano, T. & Shibata, A., 08-2018, In : Human Immunology. 79, 8, p. 627-631 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017

3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiation

Hagiwara, Y., Niimi, A., Isono, M., Yamauchi, M., Yasuhara, T., Limsirichaikul, S., Oike, T., Sato, H., Held, K. D., Nakano, T. & Shibata, A., 2017, In : Oncotarget. 8, 65, p. 109370-109381 12 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation

Isono, M., Niimi, A., Oike, T., Hagiwara, Y., Sato, H., Sekine, R., Yoshida, Y., Isobe, S. Y., Obuse, C., Nishi, R., Petricci, E., Nakada, S., Nakano, T. & Shibata, A., 10-01-2017, In : Cell Reports. 18, 2, p. 520-532 13 p.

Research output: Contribution to journalArticle

Open Access
55 Citations (Scopus)

DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells

Sato, H., Niimi, A., Yasuhara, T., Permata, T. B. M., Hagiwara, Y., Isono, M., Nuryadi, E., Sekine, R., Oike, T., Kakoti, S., Yoshimoto, Y., Held, K. D., Suzuki, Y., Kono, K., Miyagawa, K., Nakano, T. & Shibata, A., 01-12-2017, In : Nature communications. 8, 1, 1751.

Research output: Contribution to journalArticle

Open Access
122 Citations (Scopus)

Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells

Nakajima, N. I., Niimi, A., Isono, M., Oike, T., Sato, H., Nakano, T. & Shibata, A., 08-2017, In : Oncology reports. 38, 2, p. 693-702 10 p.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Mitotic catastrophe is a putative mechanism underlying the weak correlation between sensitivity to carbon ions and cisplatin

Kobayashi, D., Oike, T., Shibata, A., Niimi, A., Kubota, Y., Sakai, M., Amornwhichet, N., Yoshimoto, Y., Hagiwara, Y., Kimura, Y., Hirota, Y., Sato, H., Isono, M., Yoshida, Y., Kohno, T., Ohno, T. & Nakano, T., 16-01-2017, In : Scientific reports. 7, 40588.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1

Yamauchi, M., Shibata, A., Suzuki, K., Suzuki, M., Niimi, A., Kondo, H., Miura, M., Hirakawa, M., Tsujita, K., Yamashita, S. & Matsuda, N., 03-02-2017, In : Scientific reports. 7, 41812.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)
2016

Identification of DNA double strand breaks at chromosome boundaries along the track of particle irradiation

Niimi, A., Yamauchi, M., Limsirichaikul, S., Sekine, R., Oike, T., Sato, H., Suzuki, K., Held, K. D., Nakano, T. & Shibata, A., 01-08-2016, In : Genes Chromosomes and Cancer. 55, 8, p. 650-660 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Visualization of complex DNA double-strand breaks in a tumor treated with carbon ion radiotherapy

Oike, T., Niimi, A., Okonogi, N., Murata, K., Matsumura, A., Noda, S. E., Kobayashi, D., Iwanaga, M., Tsuchida, K., Kanai, T., Ohno, T., Shibata, A. & Nakano, T., 01-03-2016, In : Scientific reports. 6, 22275.

Research output: Contribution to journalArticle

Open Access
22 Citations (Scopus)
2015

The BAH domain of BAF180 is required for PCNA ubiquitination

Niimi, A., Hopkins, S. R., Downs, J. A. & Masutani, C., 01-09-2015, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 779, p. 16-23 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2013

Firefly luciferase as the reporter for transcriptional response to the environment in Escherichia coli

Ryo, M., Oshikoshi, Y., Doi, S., Motoki, S., Niimi, A. & Aoki, S., 01-01-2013, In : Analytical Biochemistry. 443, 2, p. 211-213 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2012

A role for chromatin remodellers in replication of damaged DNA

Niimi, A., Chambers, A. L., Downs, J. A. & Lehmann, A. R., 08-2012, In : Nucleic acids research. 40, 15, p. 7393-7403 11 p.

Research output: Contribution to journalArticle

Open Access
35 Citations (Scopus)
2010

Erratum: PCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase α (Journal of Biochemistry (2009) 146:1 (13-21) DOI: 10.1093/jb/mvp043)

Suzuki, M., Niimi, A., Limsirichaikul, S., Tomida, S., Huang, Q. M., Izuta, S., Usukura, J., Itoh, Y., Hishida, T., Akashi, T., Nakagawa, Y., Kikuchi, A., Pavlov, Y., Murate, T. & Takahashi, T., 01-08-2010, In : Journal of Biochemistry. 148, 2, 1 p.

Research output: Contribution to journalComment/debate

Functions of base selection step in human DNA polymerase α

Tanaka, S., Cao, K., Niimi, A., Limsirichaikul, S., Miao, H. Q., Nakamura, N., Murate, T., Hasegawa, Y., Takahashi, T. & Suzuki, M., 04-05-2010, In : DNA Repair. 9, 5, p. 534-541 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination

Bienko, M., Green, C. M., Sabbioneda, S., Crosetto, N., Matic, I., Hibbert, R. G., Begovic, T., Niimi, A., Mann, M., Lehmann, A. R. & Dikic, I., 12-02-2010, In : Molecular Cell. 37, 3, p. 396-407 12 p.

Research output: Contribution to journalArticle

Open Access
114 Citations (Scopus)

Three DNA Polymerases, Recruited by Different Mechanisms, Carry Out NER Repair Synthesis in Human Cells

Ogi, T., Limsirichaikul, S., Overmeer, R. M., Volker, M., Takenaka, K., Cloney, R., Nakazawa, Y., Niimi, A., Miki, Y., Jaspers, N. G., Mullenders, L. H. F., Yamashita, S., Fousteri, M. I. & Lehmann, A. R., 12-03-2010, In : Molecular Cell. 37, 5, p. 714-727 14 p.

Research output: Contribution to journalArticle

Open Access
224 Citations (Scopus)
2009

A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU)

Limsirichaikul, S., Niimi, A., Fawcett, H., Lehmann, A., Yamashita, S. & Ogi, T., 2009, In : Nucleic acids research. 37, 4, e31.

Research output: Contribution to journalArticle

Open Access
78 Citations (Scopus)

PCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase α

Suzuki, M., Niimi, A., Limsirichaikul, S., Tomida, S., Miao Huang, Q., Izuta, S., Usukura, J., Itoh, Y., Hishida, T., Akashi, T., Nakagawa, Y., Kikuchi, A., Pavlov, Y., Murate, T. & Takahashi, T., 07-2009, In : Journal of Biochemistry. 146, 1, p. 13-21 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Ubiquitination and deubiquitination of PCNA in response to stalling of the replication fork

Brown, S., Niimi, A. & Lehmann, A. R., 01-03-2009, In : Cell Cycle. 8, 5, p. 689-692 4 p.

Research output: Contribution to journalReview article

Open Access
34 Citations (Scopus)
2008

Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

Niimi, A., Brown, S., Sabbioneda, S., Kannouche, P. L., Scott, A., Yasui, A., Green, C. M. & Lehmann, A. R., 21-10-2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 42, p. 16125-16130 6 p.

Research output: Contribution to journalArticle

Open Access
131 Citations (Scopus)
2007

Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells

Murakawa, Y., Sonoda, E., Barber, L. J., Zeng, W., Yokomori, K., Kimura, H., Niimi, A., Lehmann, A., Guang, Y. Z., Hochegger, H., Boulton, S. J. & Takeda, S., 15-09-2007, In : Cancer Research. 67, 18, p. 8536-8543 8 p.

Research output: Contribution to journalArticle

Open Access
82 Citations (Scopus)

Translesion synthesis: Y-family polymerases and the polymerase switch

Lehmann, A. R., Niimi, A., Ogi, T., Brown, S., Sabbioneda, S., Wing, J. F., Kannouche, P. L. & Green, C. M., 01-07-2007, In : DNA Repair. 6, 7, p. 891-899 9 p.

Research output: Contribution to journalArticle

296 Citations (Scopus)
2006

Evidence that errors made by DNA polymerase α are corrected by DNA polymerase δ

Pavlov, Y. I., Frahm, C., McElhinny, S. A. N., Niimi, A., Suzuki, M. & Kunkel, T. A., 24-01-2006, In : Current Biology. 16, 2, p. 202-207 6 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)
2005

Role of DNA polymerase a in genome stability

Niimi, A., Limusirichaikul, S. & Suzuki, M., 03-2005, In : Seikagaku. The Journal of Japanese Biochemical Society. 77, 3, p. 200-205 6 p.

Research output: Contribution to journalReview article

2004

Palm Mutants in DNA Polymerases α and η Alter DNA Replication Fidelity and Translesion Activity

Niimi, A., Limsirichaikul, S., Yoshida, S., Iwai, S., Masutani, C., Hanaoka, F., Kool, E. T., Nishiyama, Y. & Suzuki, M., 04-2004, In : Molecular and Cellular Biology. 24, 7, p. 2734-2746 13 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)
2003

Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase α

Ogawa, M., Limsirichaikul, S., Niimi, A., Iwai, S., Yoshida, S. & Suzuki, M., 23-05-2003, In : Journal of Biological Chemistry. 278, 21, p. 19071-19078 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The Gly-952 residue of Saccharomyces cerevisiae DNA polymerase α is important in discriminating correct deoxyribonucleotides from incorrect ones

Limsirichaikul, S., Ogawa, M., Niimi, A., Iwai, S., Murate, T., Yoshida, S. & Suzuki, M., 23-05-2003, In : Journal of Biological Chemistry. 278, 21, p. 19079-19086 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)