• 114 Citations
  • 6 h-Index
20102019
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Research Output 2010 2019

  • 114 Citations
  • 6 h-Index
  • 12 Article
  • 3 Conference contribution
  • 1 Chapter
2019

Influx of Tau and Amyloid-β Proteins into the Blood during Hemodialysis as a Therapeutic Extracorporeal Blood Amyloid-β Removal System for Alzheimer's Disease

Kitaguchi, N., Tatebe, H., Sakai, K., Kawaguchi, K., Matsunaga, S., Kitajima, T., Tomizawa, H., Kato, M., Sugiyama, S., Suzuki, N., Mizuno, M., Takechi, H., Nakai, S., Hiki, Y., Kushimoto, H., Hasegawa, M., Yuzawa, Y. & Tokuda, T., 01-01-2019, In : Journal of Alzheimer's Disease. 69, 3, p. 687-707 21 p.

Research output: Contribution to journalArticle

Amyloidogenic Proteins
tau Proteins
Amyloid
Renal Dialysis
Alzheimer Disease
2018
2 Citations (Scopus)

Adsorptive filtration systems for effective removal of blood amyloid β: a potential therapy for Alzheimer’s disease

Kitaguchi, N., Kawaguchi, K., Yamazaki, K., Kawachi, H., Sakata, M., Kaneko, M., Kato, M., Sakai, K., Ohashi, N., Hasegawa, M., Hiki, Y. & Yuzawa, Y., 01-06-2018, In : Journal of Artificial Organs. 21, 2, p. 220-229 10 p.

Research output: Contribution to journalArticle

Amyloid
Alzheimer Disease
Blood
Brain
Adsorption
1 Citation (Scopus)

Removal of blood amyloid as a therapeutic strategy for alzheimer's disease: The influence of smoking and nicotine

Kitaguchi, N., Kawaguchi, K. & Sakai, K., 04-04-2018, Nicotinic Acetylcholine Receptor Signaling in Neuroprotection. Springer Singapore, p. 173-191 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nicotine
Amyloid
Alzheimer Disease
Smoking
Brain
2 Citations (Scopus)

Removal of blood amyloid-β with hemodialysis reduced brain amyloid-β, confirmed by brain imaging: A case report

Kitaguchi, N., Kato, T., Matsunaga, S., Hirano, K., Iwata, K., Kawaguchi, K., Fujita, K., Takechi, H., Hasegawa, M., Yuzawa, Y. & Ito, K., 01-01-2018, In : Neuropsychiatric Disease and Treatment. 14, p. 2931-2937 7 p.

Research output: Contribution to journalArticle

Amyloid
Neuroimaging
Renal Dialysis
Brain
Alzheimer Disease
2016

A medical training system for the operation of Heart-lung machine

Kanehira, R., Hori, H., Kawaguchi, K. & Fujimoto, H., 13-01-2016, 2015 12th International Conference on Fuzzy Systems and Knowledge Discovery, FSKD 2015. Tang, Z., Du, J., Yin, S., Li, R. & He, L. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 2464-2468 5 p. 7382341

Research output: Chapter in Book/Report/Conference proceedingConference contribution

E-learning
Textbooks
Information use
Lung
Education
10 Citations (Scopus)

Patients that have undergone hemodialysis exhibit lower amyloid deposition in the brain: Evidence supporting a therapeutic strategy for Alzheimer's disease by removal of blood amyloid

Sakai, K., Senda, T., Hata, R., Kuroda, M., Hasegawa, M., Kato, M., Abe, M., Kawaguchi, K., Nakai, S., Hiki, Y., Yuzawa, Y. & Kitaguchi, N., 12-04-2016, In : Journal of Alzheimer's Disease. 51, 4, p. 997-1002 6 p.

Research output: Contribution to journalArticle

Amyloid
Renal Dialysis
Alzheimer Disease
Brain
Silver Staining
5 Citations (Scopus)
Amyloidogenic Proteins
Polysulfones
Polymethyl Methacrylate
Polymethyl methacrylates
Adsorption
2015
5 Citations (Scopus)

Appropriate nonwoven filters effectively capture human peripheral blood cells and mesenchymal stem cells, which show enhanced production of growth factors

Hori, H., Iwamoto, U., Niimi, G., Shinzato, M., Hiki, Y., Tokushima, Y., Kawaguchi, K., Ohashi, A., Nakai, S., Yasutake, M. & Kitaguchi, N., 01-01-2015, In : Journal of Artificial Organs. 18, 1, p. 55-63 9 p.

Research output: Contribution to journalArticle

Stem cells
Mesenchymal Stromal Cells
Polyethylene Terephthalates
Blood Cells
Intercellular Signaling Peptides and Proteins
16 Citations (Scopus)

A prospective study on blood Aβ levels and the cognitive function of patients with hemodialysis: a potential therapeutic strategy for Alzheimer’s disease

Kitaguchi, N., Hasegawa, M., Ito, S., Kawaguchi, K., Hiki, Y., Nakai, S., Suzuki, N., Shimano, Y., Ishida, O., Kushimoto, H., Kato, M., Koide, S., Kanayama, K., Kato, T., Ito, K., Takahashi, H., Mutoh, T., Sugiyama, S. & Yuzawa, Y., 01-11-2015, In : Journal of Neural Transmission. 122, 11, p. 1593-1607 15 p.

Research output: Contribution to journalArticle

Cognition
Renal Dialysis
Alzheimer Disease
Prospective Studies
Brain
1 Citation (Scopus)

Learning-training system for medical equipment operation

Kanehira, R., Kawaguchi, K. & Fujimoto, H., 01-01-2015, HCI International 2015 - Posters Extended Abstracts - International Conference, HCI International 2015, Proceedings. Springer Verlag, p. 321-327 7 p. (Communications in Computer and Information Science; vol. 529).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomedical equipment
Education
Engineers
Shooting
Students
2014
6 Citations (Scopus)

A training system for operating medical equipment

Kanehira, R., Narita, H., Kawaguchi, K., Hori, H. & Fujimoto, H., 28-02-2014, Frontier and Future Development of Information Technology in Medicine and Education, ITME 2013. p. 2259-2265 7 p. (Lecture Notes in Electrical Engineering; vol. 269 LNEE).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomedical equipment
Education
Engineers
Communication
6 Citations (Scopus)

Computer-Supported Training System for Clinical Engineer

Kanehira, R., Hori, H., Kawaguchi, K. & Fujimoto, H., 01-01-2014, In : Communications in Computer and Information Science. 435 PART II, p. 89-94 6 p.

Research output: Contribution to journalArticle

Engineers
Information and Communication Technology
Communication
Teaching
Computer systems
2013
6 Citations (Scopus)

A potential therapeutic system for Alzheimer's disease using adsorbents with alkyl ligands for removal of blood amyloid β

Kawaguchi, K., Takeuchi, M., Yamagawa, H., Murakami, K., Nakai, S., Hori, H., Ohashi, A., Hiki, Y., Suzuki, N., Sugiyama, S., Yuzawa, Y. & Kitaguchi, N., 01-06-2013, In : Journal of Artificial Organs. 16, 2, p. 211-217 7 p.

Research output: Contribution to journalArticle

Amyloid
Cellulose
Adsorbents
Alzheimer Disease
Blood
2012
18 Citations (Scopus)

Potential therapeutic system for Alzheimer's disease: Removal of blood Aβs by hemodialzyers and its effect on the cognitive functions of renal-failure patients

Kato, M., Kawaguchi, K., Nakai, S., Murakami, K., Hori, H., Ohashi, A., Hiki, Y., Ito, S., Shimano, Y., Suzuki, N., Sugiyama, S., Ogawa, H., Kusimoto, H., Mutoh, T., Yuzawa, Y. & Kitaguchi, N., 01-12-2012, In : Journal of Neural Transmission. 119, 12, p. 1533-1544 12 p.

Research output: Contribution to journalArticle

Cognition
Renal Insufficiency
Renal Dialysis
Alzheimer Disease
Therapeutics
2011
18 Citations (Scopus)

Reduction of Alzheimer's disease amyloid-β in plasma by hemodialysis and its relation to cognitive functions

Kitaguchi, N., Kawaguchi, K., Nakai, S., Murakami, K., Ito, S., Hoshino, H., Hori, H., Ohashi, A., Shimano, Y., Suzuki, N., Yuzawa, Y., Mutoh, T. & Sugiyama, S., 01-07-2011, In : Blood Purification. 32, 1, p. 57-62 6 p.

Research output: Contribution to journalArticle

Amyloid
Cognition
Renal Dialysis
Alzheimer Disease
Dialysis
2010
18 Citations (Scopus)

Novel therapeutic approach for Alzheimer's disease by removing amyloid β protein from the brain with an extracorporeal removal system

Kawaguchi, K., Kitaguchi, N., Nakai, S., Murakami, K., Asakura, K., Mutoh, T., Fujita, Y. & Sugiyama, S., 01-04-2010, In : Journal of Artificial Organs. 13, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

Amyloidogenic Proteins
Brain
Alzheimer Disease
Cellulose
G(M1) Ganglioside