• 138 Citations
  • 7 h-Index
20102020

Research output per year

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Research Output

  • 138 Citations
  • 7 h-Index
  • 15 Article
  • 3 Conference contribution
  • 1 Chapter
2020

Removal of aβ oligomers from the blood: A potential therapeutic system for alzheimer’s disease

Saito, Y., Sakata, M., Kobayakawa, M., Kawachi, H., Kawaguchi, K., Hiki, Y., Kato, M., Mori, M., Hasegawa, M., Ohashi, N., Yuzawa, Y. & Kitaguchi, N., 01-01-2020, In : Neuropsychiatric Disease and Treatment. 16, p. 607-627 21 p.

Research output: Contribution to journalArticle

Open Access
2019

A medical training system for the operation of heart-lung machine

Kanehira, R., Hori, H., Kawaguchi, K. & Fujimoto, H., 01-01-2019, In : International Journal of Computational Science and Engineering. 19, 4, p. 554-561 8 p.

Research output: Contribution to journalArticle

Influx of Tau and Amyloid-β Proteins into the Blood during Hemodialysis as a Therapeutic Extracorporeal Blood Amyloid-β Removal System for Alzheimer's Disease

Kitaguchi, N., Tatebe, H., Sakai, K., Kawaguchi, K., Matsunaga, S., Kitajima, T., Tomizawa, H., Kato, M., Sugiyama, S., Suzuki, N., Mizuno, M., Takechi, H., Nakai, S., Hiki, Y., Kushimoto, H., Hasegawa, M., Yuzawa, Y. & Tokuda, T., 01-01-2019, In : Journal of Alzheimer's Disease. 69, 3, p. 687-707 21 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2018

Adsorptive filtration systems for effective removal of blood amyloid β: a potential therapy for Alzheimer’s disease

Kitaguchi, N., Kawaguchi, K., Yamazaki, K., Kawachi, H., Sakata, M., Kaneko, M., Kato, M., Sakai, K., Ohashi, N., Hasegawa, M., Hiki, Y. & Yuzawa, Y., 01-06-2018, In : Journal of Artificial Organs. 21, 2, p. 220-229 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Is hemodialysis itself a risk factor for dementia? An analysis of nationwide registry data of patients on maintenance hemodialysis in Japan

Nakai, S., Wakai, K., Kanda, E., Kawaguchi, K., Sakai, K. & Kitaguchi, N., 14-03-2018, In : Renal Replacement Therapy. 4, 1, 12.

Research output: Contribution to journalArticle

Open Access

Removal of blood amyloid as a therapeutic strategy for alzheimer's disease: The influence of smoking and nicotine

Kitaguchi, N., Kawaguchi, K. & Sakai, K., 04-04-2018, Nicotinic Acetylcholine Receptor Signaling in Neuroprotection. Springer Singapore, p. 173-191 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Removal of blood amyloid-β with hemodialysis reduced brain amyloid-β, confirmed by brain imaging: A case report

Kitaguchi, N., Kato, T., Matsunaga, S., Hirano, K., Iwata, K., Kawaguchi, K., Fujita, K., Takechi, H., Hasegawa, M., Yuzawa, Y. & Ito, K., 01-01-2018, In : Neuropsychiatric Disease and Treatment. 14, p. 2931-2937 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016

A medical training system for the operation of Heart-lung machine

Kanehira, R., Hori, H., Kawaguchi, K. & Fujimoto, H., 13-01-2016, 2015 12th International Conference on Fuzzy Systems and Knowledge Discovery, FSKD 2015. Tang, Z., Du, J., Yin, S., Li, R. & He, L. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 2464-2468 5 p. 7382341

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Patients that have undergone hemodialysis exhibit lower amyloid deposition in the brain: Evidence supporting a therapeutic strategy for Alzheimer's disease by removal of blood amyloid

Sakai, K., Senda, T., Hata, R., Kuroda, M., Hasegawa, M., Kato, M., Abe, M., Kawaguchi, K., Nakai, S., Hiki, Y., Yuzawa, Y. & Kitaguchi, N., 12-04-2016, In : Journal of Alzheimer's Disease. 51, 4, p. 997-1002 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Toward the treatment for Alzheimer’s disease: adsorption is primary mechanism of removing amyloid β protein with hollow-fiber dialyzers of the suitable materials, polysulfone and polymethyl methacrylate

Kawaguchi, K., Saigusa, A., Yamada, S., Gotoh, T., Nakai, S., Hiki, Y., Hasegawa, M., Yuzawa, Y. & Kitaguchi, N., 01-06-2016, In : Journal of Artificial Organs. 19, 2, p. 149-158 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2015

Appropriate nonwoven filters effectively capture human peripheral blood cells and mesenchymal stem cells, which show enhanced production of growth factors

Hori, H., Iwamoto, U., Niimi, G., Shinzato, M., Hiki, Y., Tokushima, Y., Kawaguchi, K., Ohashi, A., Nakai, S., Yasutake, M. & Kitaguchi, N., 01-01-2015, In : Journal of Artificial Organs. 18, 1, p. 55-63 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

A prospective study on blood Aβ levels and the cognitive function of patients with hemodialysis: a potential therapeutic strategy for Alzheimer’s disease

Kitaguchi, N., Hasegawa, M., Ito, S., Kawaguchi, K., Hiki, Y., Nakai, S., Suzuki, N., Shimano, Y., Ishida, O., Kushimoto, H., Kato, M., Koide, S., Kanayama, K., Kato, T., Ito, K., Takahashi, H., Mutoh, T., Sugiyama, S. & Yuzawa, Y., 01-11-2015, In : Journal of Neural Transmission. 122, 11, p. 1593-1607 15 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Learning-training system for medical equipment operation

Kanehira, R., Kawaguchi, K. & Fujimoto, H., 01-01-2015, HCI International 2015 - Posters Extended Abstracts - International Conference, HCI International 2015, Proceedings. Stephanidis, C. (ed.). Springer Verlag, p. 321-327 7 p. (Communications in Computer and Information Science; vol. 529).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)
2014

A training system for operating medical equipment

Kanehira, R., Narita, H., Kawaguchi, K., Hori, H. & Fujimoto, H., 28-02-2014, Frontier and Future Development of Information Technology in Medicine and Education, ITME 2013. p. 2259-2265 7 p. (Lecture Notes in Electrical Engineering; vol. 269 LNEE).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Computer-Supported Training System for Clinical Engineer

Kanehira, R., Hori, H., Kawaguchi, K. & Fujimoto, H., 01-01-2014, In : Communications in Computer and Information Science. 435 PART II, p. 89-94 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2013

A potential therapeutic system for Alzheimer's disease using adsorbents with alkyl ligands for removal of blood amyloid β

Kawaguchi, K., Takeuchi, M., Yamagawa, H., Murakami, K., Nakai, S., Hori, H., Ohashi, A., Hiki, Y., Suzuki, N., Sugiyama, S., Yuzawa, Y. & Kitaguchi, N., 01-06-2013, In : Journal of Artificial Organs. 16, 2, p. 211-217 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2012

Potential therapeutic system for Alzheimer's disease: Removal of blood Aβs by hemodialzyers and its effect on the cognitive functions of renal-failure patients

Kato, M., Kawaguchi, K., Nakai, S., Murakami, K., Hori, H., Ohashi, A., Hiki, Y., Ito, S., Shimano, Y., Suzuki, N., Sugiyama, S., Ogawa, H., Kusimoto, H., Mutoh, T., Yuzawa, Y. & Kitaguchi, N., 01-12-2012, In : Journal of Neural Transmission. 119, 12, p. 1533-1544 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2011

Reduction of Alzheimer's disease amyloid-β in plasma by hemodialysis and its relation to cognitive functions

Kitaguchi, N., Kawaguchi, K., Nakai, S., Murakami, K., Ito, S., Hoshino, H., Hori, H., Ohashi, A., Shimano, Y., Suzuki, N., Yuzawa, Y., Mutoh, T. & Sugiyama, S., 01-07-2011, In : Blood Purification. 32, 1, p. 57-62 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2010

Novel therapeutic approach for Alzheimer's disease by removing amyloid β protein from the brain with an extracorporeal removal system

Kawaguchi, K., Kitaguchi, N., Nakai, S., Murakami, K., Asakura, K., Mutoh, T., Fujita, Y. & Sugiyama, S., 01-04-2010, In : Journal of Artificial Organs. 13, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)