• 494 Citations
  • 11 h-Index
20052020

Research output per year

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Research Output

  • 494 Citations
  • 11 h-Index
  • 51 Article
  • 2 Chapter
  • 1 Review article
2020

Analysis of O-glycoforms of the IgA1 hinge region by sequential deglycosylation

Ohyama, Y., Yamaguchi, H., Nakajima, K., Mizuno, T., Fukamachi, Y., Yokoi, Y., Tsuboi, N., Inaguma, D., Hasegawa, M., Renfrow, M. B., Novak, J., Yuzawa, Y. & Takahashi, K., 01-12-2020, In : Scientific reports. 10, 1, 671.

Research output: Contribution to journalArticle

Open Access

CD140b and CD73 are markers for human induced pluripotent stem cell-derived erythropoietin-producing cells

Nishimoto, S., Mizuno, T., Takahashi, K., Nagano, F., Yuzawa, Y., Nishiyama, A., Osafune, K., Hitomi, H. & Nagamatsu, T., 01-03-2020, In : FEBS Open Bio. 10, 3, p. 427-433 7 p.

Research output: Contribution to journalArticle

Open Access
2019

Comparison Between the Internal and External Pressure Filtration Method of Cell-Free and Concentrated Ascites Reinfusion Therapy Using the Same Cancerous Ascites

Yamada, S., Hasegawa, M., Nii, N., Kato, M., Ohashi, A., Suzuki, R., Komatsu, M., Abe, K., Hata, Y., Takahashi, K., Hayashi, H., Koide, S., Tsuboi, N., Inaguma, D. & Yuzawa, Y., 06-2019, In : Therapeutic Apheresis and Dialysis. 23, 3, p. 237-241 5 p.

Research output: Contribution to journalArticle

IgA1 hinge-region clustered glycan fidelity is established early during semi-ordered glycosylation by GalNAc-T2

Stewart, T. J., Takahashi, K., Whitaker, R. H., Raska, M., Placzek, W. J., Novak, J. & Renfrow, M. B., 01-01-2019, In : Glycobiology. 29, 7, p. 543-556 14 p., cwz007.

Research output: Contribution to journalArticle

Oral ferrous citrate or ferrous sulfate use during predialysis may reduce serum phosphate level at dialysis initiation


Koide, S., Inaguma, D., Koshi-Ito, E., Takahashi, K., Hayashi, H., Tsuboi, N., Hasegawa, M. & Yuzawa, Y., 01-10-2019, In : Clinical nephrology. 92, 4, p. 180-189 10 p.

Research output: Contribution to journalArticle

Prediction model for cardiovascular events or all-cause mortality in incident dialysis patients

Inaguma, D., Morii, D., Kabata, D., Yoshida, H., Tanaka, A., Koshi-Ito, E., Takahashi, K., Hayashi, H., Koide, S., Tsuboi, N., Hasegawa, M., Shintani, A. & Yuzawa, Y., 01-01-2019, In : PloS one. 14, 8, e0221352.

Research output: Contribution to journalArticle

Open Access

Relationship between history of ischemic stroke and all-cause mortality in incident dialysis patients

Kojima, M., Inaguma, D., Koide, S., Koshi-Ito, E., Takahashi, K., Hayashi, H., Tsuboi, N., Hasegawa, M. & Yuzawa, Y., 01-09-2019, In : Nephron. 143, 1, p. 43-53 11 p.

Research output: Contribution to journalArticle

Open Access

Relationship Between Patterns in Antihypertensive Drugs Medication and Mortality in Incident Dialysis Patients: A Multicenter Prospective Cohort Study

Fujii, M., Inaguma, D., Koide, S., Ito, E., Takahashi, K., Hayashi, H., Tsuboi, N., Hasegawa, M. & Yuzawa, Y., 01-01-2019, In : Therapeutic Apheresis and Dialysis. 23, 4, p. 353-361 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Aortic stenosis is a risk factor for all-cause mortality in patients on dialysis: A multicenter prospective cohort analysis

Inaguma, D., Sasakawa, Y., Suzuki, N., Ito, E., Takahashi, K., Hayashi, H., Koide, S., Hasegawa, M., Yuzawa, Y., Tamai, H., Tsutsui, S., Ueda, T., Narita, Y., Sofue, F., Hirano, Y., Motokawa, M., Miwa, M., Suzuki, N., Kojima, S., Takatsu, H. & 60 others, Akahori, T., Murakami, K., Shimano, Y., Miyazaki, T., Baba, K., Iida, Y., Endo, H., Furuya, R., Aoyama, I., Mizutani, Y., Seno, H., Nagaya, T., Kasuga, H., Sugiyama, S., Kojima, K., Fujisawa, K., Naruse, T., Ishida, O., Oishi, H., Ono, A., Shimizu, H., Kato, K., Ito, I., Yasutomi, S., Yamazaki, C., Yasuda, K., Matsuoka, T., Tsuruta, Y., Mizuno, M., Ono, M., Okada, M., Tanoue, A., Obayashi, T., Yokoyama, I., Kushimoto, H., Hasegawa, H., Kawasumi, M., Nomura, A., Sakurauchi, Y., Yamashita, M., Asada, H., Ohara, K., Koyabu, S., Tada, M., Sato, F., Yamaguchi, S., Ogawa, H., Ota, Y., Matsumoto, Y., Otsuka, S., Namii, Y., Kasai, Y., Kato, N., Nakayama, M., Sato, H., Inaba, S., Shibata, M., Yamashita, H., Yamamoto, J. & Yamaguchi, M., 03-04-2018, In : BMC Nephrology. 19, 1, 80.

Research output: Contribution to journalArticle

Association between resting heart rate just before starting the first dialysis session and mortality: A multicentre prospective cohort study

AICOPP group, 05-2018, In : Nephrology. 23, 5, p. 461-468 8 p.

Research output: Contribution to journalArticle

Chondroitin sulfate protects vascular endothelial cells from toxicities of extracellular histones

Nagano, F., Mizuno, T., Mizumoto, S., Yoshioka, K., Takahashi, K., Tsuboi, N., Maruyama, S., Yamada, S. & Nagamatsu, T., 05-05-2018, In : European Journal of Pharmacology. 826, p. 48-55 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Detection and identification of potential transglutaminase 2 substrates in the mouse renal glomeruli author names and affiliations

Ito, Y., Tatsukawa, H., Yamaguchi, H., Takahashi, K., Hitomi, K. & Yuzawa, Y., 15-12-2018, In : Archives of Biochemistry and Biophysics. 660, p. 11-19 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Identification and characterization of UDP-mannose in human cell lines and mouse organs: Differential distribution across brain regions and organs

Nakajima, K., Kizuka, Y., Yamaguchi, Y., Hirabayashi, Y., Takahashi, K., Yuzawa, Y. & Taniguchi, N., 01-01-2018, In : Biochemical and Biophysical Research Communications. 495, 1, p. 401-407 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2 Citations (Scopus)

Progression of immunoglobulin G4-related disease to systematic lupus erythematosus after gastric cancer surgery: A case report

Arai, H., Hayashi, H., Ogata, S., Uto, K., Saegusa, J., Takahashi, K., Koide, S., Inaguma, D., Hasegawa, M. & Yuzawa, Y., 12-2018, In : Medicine (United States). 97, 51, e13545.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Serum phosphate level at initiation of dialysis is associated with all-cause mortality: a multicenter prospective cohort study

AICOPP group, 01-11-2018, In : Renal failure. 40, 1, p. 475-482 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017
2 Citations (Scopus)
3 Citations (Scopus)
2016

A retrospective study on the outcomes of MPO-ANCA-associated vasculitis in dialysis-dependent patients

Hasegawa, M., Hattori, K., Sugiyama, S., Asada, H., Yamashita, H., Takahashi, K., Hayashi, H., Koide, S., Sato, W. & Yuzawa, Y., 02-01-2016, In : Modern Rheumatology. 26, 1, p. 110-114 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Evidence-based clinical practice guidelines for IgA nephropathy 2014

Yuzawa, Y., Yamamoto, R., Takahashi, K., Katafuchi, R., Tomita, M., Fujigaki, Y., Kitamura, H., Goto, M., Yasuda, T., Sato, M., Urushihara, M., Kondo, S., Kagami, S., Yasuda, Y., Komatsu, H., Takahara, M., Harabuchi, Y., Kimura, K. & Matsuo, S., 01-08-2016, In : Clinical and Experimental Nephrology. 20, 4, p. 511-535 25 p.

Research output: Contribution to journalReview article

17 Citations (Scopus)

Heterogeneity of aberrant O-glycosylation of IgA1 in IgA nephropathy

Novak, J., Takahashi, K., Suzuki, H., Reily, C., Stewart, T., Ueda, H., Yamada, K., Moldoveanu, Z., Hastings, M. C., Wyatt, R. J., Mestecky, J., Raska, M., Julian, B. A. & Renfrow, M. B., 10-03-2016, Pathogenesis and Treatment in IgA Nephropathy: An International Comparison. Springer Japan, p. 53-68 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

In a retrospective international study, circulating MIR-148b and let-7b were found to be serum markers for detecting primary IgA nephropathy

Serino, G., Pesce, F., Sallustio, F., De Palma, G., Cox, S. N., Curci, C., Zaza, G., Lai, K. N., Leung, J. C. K., Tang, S. C. W., Papagianni, A., Stangou, M., Goumenos, D., Gerolymos, M., Takahashi, K., Yuzawa, Y., Maruyama, S., Imai, E. & Schena, F. P., 01-03-2016, In : Kidney International. 89, 3, p. 683-692 10 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Japanese clinical practice guidelines for IgA nephropathy: Difference from KDIGO guidelines

Takahashi, K., Yamamoto, R. & Yuzawa, Y., 10-03-2016, Pathogenesis and Treatment in IgA Nephropathy: An International Comparison. Springer Japan, p. 251-262 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Kidney transplantation, cardiovascular risk, and long-term dialysis in Japan

Tada, M., Hasegawa, M., Sasaki, H., Kusaka, M., Shiroki, R., Hoshinaga, K., Ito, T., Kenmochi, T., Nakai, S., Takahashi, K., Hayashi, H., Koide, S. & Yuzawa, Y., 01-01-2016, In : Transplantation Proceedings. 48, 1, p. 26-30 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Lower blood pressure-induced renal hypoperfusion promotes cisplatin-induced nephrotoxicity

Mizuno, T., Hayashi, T., Shimabukuro, Y., Murase, M., Hayashi, H., Ishikawa, K., Takahashi, K., Yuzawa, Y., Yamada, S. & Nagamatsu, T., 14-06-2016, In : Oncology (Switzerland). 90, 6, p. 313-320 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Plasma Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Cardiovascular Events in Patients with Chronic Kidney Disease

Hasegawa, M., Ishii, J., Kitagawa, F., Takahashi, H., Sugiyama, K., Tada, M., Kanayama, K., Takahashi, K., Hayashi, H., Koide, S., Nakai, S., Ozaki, Y. & Yuzawa, Y., 01-01-2016, In : BioMed Research International. 2016, 8761475.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Post-transplant membranous nephropathy associated with chronic active antibody-mediated rejection and hepatitis C infection after deceased donor renal transplantation

Doke, T., Sato, W., Takahashi, K., Hayashi, H., Koide, S., Sasaki, H., Kusaka, M., Shiroki, R., Hoshinaga, K., Takeda, A., Yuzawa, Y. & Hasegawa, M., 15-02-2016, In : Internal Medicine. 55, 4, p. 375-380 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The level of IgA antibodies to endothelial cells correlates with histological evidence of disease activity in patients with lupus nephritis

Kondo, A., Takahashi, K., Mizuno, T., Kato, A., Hirano, D., Yamamoto, N., Hayashi, H., Koide, S., Takahashi, H., Hasegawa, M., Hiki, Y., Yoshida, S., Miura, K. & Yuzawa, Y., 10-2016, In : PloS one. 11, 10, e0163085.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015

N-Acetylgalactosaminide α2,6-sialyltransferase II is a candidate enzyme for sialylation of galactose-deficient IgA1, the key autoantigen in IgA nephropathy

Horynova, M. S., Vrablikova, A., Stewart, T. J., Takahashi, K., Czernekova, L., Yamada, K., Suzuki, H., Julian, B. A., Renfrow, M. B., Novak, J. & Raska, M., 01-02-2015, In : Nephrology Dialysis Transplantation. 30, 2, p. 234-238 5 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Significance of downregulation of renal organic cation transporter (SLC47A1) in cisplatin-induced proximal tubular injury

Mizuno, T., Sato, W., Ishikawa, K., Terao, Y., Takahashi, K., Noda, Y., Yuzawa, Y. & Nagamatsu, T., 10-07-2015, In : OncoTargets and Therapy. 8, p. 1701-1706 6 p., A198.

Research output: Contribution to journalArticle

Specificity of two monoclonal antibodies against a synthetic glycopeptide, an analogue to the hypo-galactosylated IgA1 hinge region

Hiki, Y., Hori, H., Yamamoto, K., Yamamoto, Y., Yuzawa, Y., Kitaguchi, N. & Takahashi, K., 01-04-2015, In : Journal of Nephrology. 28, 2, p. 181-186 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Tubulointerstitial fibrosis in patients with IgG4-related kidney disease: Pathological findings on repeat renal biopsy

Arai, H., Hayashi, H., Takahashi, K., Koide, S., Sato, W., Hasegawa, M., Yamaguchi, Y., Aten, J., Ito, Y. & Yuzawa, Y., 28-06-2015, In : Rheumatology International. 35, 6, p. 1093-1101 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Urinary neutrophil gelatinase-associated lipocalin as a predictor of cardiovascular events in patients with chronic kidney disease

Hasegawa, M., Ishii, J., Kitagawa, F., Takahashi, K., Hayashi, H., Koide, S., Tomita, M., Takahashi, H., Ozaki, Y. & Yuzawa, Y., 01-01-2015, In : Heart and Vessels. 30, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2014

Efficacy and safety of febuxostat in elderly female patients

Mizuno, T., Hayashi, T., Hikosaka, S., Shimabukuro, Y., Murase, M., Takahashi, K., Hayashi, H., Yuzawa, Y., Nagamatsu, T. & Yamada, S., 04-09-2014, In : Clinical Interventions in Aging. 9, p. 1489-1493 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Enzymatic sialylation of IgA1 O-glycans: Implications for studies of IgA nephropathy

Takahashi, K., Raska, M., Horynova, M. S., Hall, S. D., Poulsen, K., Kilian, M., Hiki, Y., Yuzawa, Y., Moldoveanu, Z., Julian, B. A., Renfrow, M. B. & Novak, J., 11-06-2014, In : PloS one. 9, 6, e99026.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2013

Comparison of effective impact among tonsillectomy alone, tonsillectomy combined with oral steroid and with steroid pulse therapy on long-term outcome of immunoglobulin a nephropathy

Yamamoto, Y., Hiki, Y., Nakai, S., Yamamoto, K., Takahashi, K., Koide, S., Murakami, K., Tomita, M., Hasegawa, M., Kawashima, S., Sugiyama, S. & Yuzawa, Y., 01-01-2013, In : Clinical and Experimental Nephrology. 17, 2, p. 218-224 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2012

Naturally occurring structural isomers in serum IgA1 O -glycosylation

Takahashi, K., Smith, A. D., Poulsen, K., Kilian, M., Julian, B. A., Mestecky, J., Novak, J. & Renfrow, M. B., 03-02-2012, In : Journal of Proteome Research. 11, 2, p. 692-702 11 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Production of N-acetylgalactosaminyl-transferase 2 (GalNAc-T2) fused with secretory signal Igκ in insect cells

Horynová, M., Takahashi, K., Hall, S., Renfrow, M. B., Novak, J. & Raška, M., 01-02-2012, In : Protein Expression and Purification. 81, 2, p. 175-180 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2010

Clustered O-glycans of IgA1: Defining macro- and microheterogeneity by use of electron capture/transfer dissociation

Takahashi, K., Wall, S. B., Suzuki, H., Smith IV, A. D., Hall, S., Poulsen, K., Kilian, M., Mobley, J. A., Julian, B. A., Mestecky, J., Novak, J. & Renfrow, M. B., 01-11-2010, In : Molecular and Cellular Proteomics. 9, 11, p. 2545-2557 13 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Evaluation of the specific structures of IgA1 hinge glycopeptide in 30 IgA nephropathy patients by mass spectrometry

Odani, H., Yamamoto, K., Iwayama, S., Iwase, H., Takasaki, A., Takahashi, K., Fujita, Y., Sugiyama, S. & Hiki, Y., 01-01-2010, In : Journal of Nephrology. 23, 1, p. 70-76 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition

Raska, M., Takahashi, K., Czernekova, L., Zachova, K., Hall, S., Moldoveanu, Z., Elliott, M. C., Wilson, L., Brown, R., Jancova, D., Barnes, S., Vrbkova, J., Tomana, M., Smith, P. D., Mestecky, J., Renfrow, M. B. & Novak, J., 02-07-2010, In : Journal of Biological Chemistry. 285, 27, p. 20860-20869 10 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)
2009

A library of mutated Maackia amurensis hemagglutinin distinguishes putative glycoforms of immunoglobulin A1 from IgA nephropathy patients

Maenuma, K., Yim, M., Komatsu, K., Hoshino, M., Tachiki-Fujioka, A., Takahashi, K., Hiki, Y., Bovin, N. & Irimura, T., 06-07-2009, In : Journal of Proteome Research. 8, 7, p. 3617-3624 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2008

Analysis of IgA1 N-glycosylation and its contribution to FcαRI binding

Gomes, M. M., Wall, S. B., Takahashi, K., Novak, J., Renfrow, M. B. & Herr, A. B., 28-10-2008, In : Biochemistry. 47, 43, p. 11285-11299 15 p.

Research output: Contribution to journalArticle

Protective role of anti-synthetic hinge peptide antibody for glomerular deposition of hypoglycosylated IgA1

Hiki, Y., Takahashi, K., Shimozato, S., Odani, H., Yamamoto, K., Tomita, M., Hasegawa, M., Murakami, K., Nabeshima, K., Nakai, S., Fujita, Y., Ishida, I., Iwase, H. & Sugiyama, S., 01-02-2008, In : Clinical and Experimental Nephrology. 12, 1, p. 20-27 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Serum under-galactosylated IgA1 is increased in Japanese patients with IgA nephropathy

Shimozato, S., Hiki, Y., Odani, H., Takahashi, K., Yamamoto, K. & Sugiyama, S., 01-06-2008, In : Nephrology Dialysis Transplantation. 23, 6, p. 1931-1939 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2007

Accumulation of bisphenol A in hemodialysis patients

Murakami, K., Ohashi, A., Hori, H., Hibiya, M., Shoji, Y., Kunisaki, M., Akita, M., Yagi, A., Sugiyama, K., Shimozato, S., Ito, K., Takahashi, H., Takahashi, K., Yamamoto, K., Kasugai, M., Kawamura, N., Nakai, S., Hasegawa, M., Tomita, M., Nabeshima, K. & 2 others, Hiki, Y. & Sugiyama, S., 01-07-2007, In : Blood Purification. 25, 3, p. 290-294 5 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2006

Experimental model of IgA nephropathy using KM mouse (second report): Possible protective effect of anti-IgA1 synthetic hinge peptide antibody on glomerular deposition of underglycosylated IgA1

Hiki, Y., Takahashi, K., Itoh, M., Inoue, K., Tomita, M., Hasegawa, M., Murakami, K., Nabeshima, K., Ishida, I., Iwase, H. & Sugiyama, S., 01-10-2006, In : Nephrology. 11, SUPPL. 3, p. A57

Research output: Contribution to journalArticle

Structural analyses of O-glycan sugar chains on IgA1 hinge region using SELDI-TOFMS with various lectins

Takahashi, K., Hiki, Y., Odani, H., Shimozato, S., Iwase, H., Sugiyama, S. & Usuda, N., 24-11-2006, In : Biochemical and Biophysical Research Communications. 350, 3, p. 580-587 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)