• 670 Citations
  • 15 h-Index
19972018
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Research Output 1997 2018

  • 670 Citations
  • 15 h-Index
  • 31 Article
  • 1 Short survey
2018
2 Citations (Scopus)

Association of subcutaneous and visceral fat with circulating microRNAs in a middle-aged Japanese population

Munetsuna, E., Yamada, H., Ando, Y., Yamazaki, M., Tsuboi, Y., Kondo, M., Mizuno, G., Ishikawa, H., Sugimoto, K., Osakabe, K., Ichino, N., Ohashi, K., Hamajima, N. & Suzuki, K., 01-07-2018, In : Annals of Clinical Biochemistry. 55, 4, p. 437-445 9 p.

Research output: Contribution to journalArticle

Intra-Abdominal Fat
Subcutaneous Fat
MicroRNAs
Fats
Tissue
2 Citations (Scopus)

Oxidized human serum albumin as a possible correlation factor for atherosclerosis in a rural Japanese population: The results of the Yakumo Study

Fujii, R., Ueyama, J., Aoi, A., Ichino, N., Osakabe, K., Sugimoto, K., Suzuki, K., Hamajima, N., Wakai, K. & Kondo, T., 02-01-2018, In : Environmental Health and Preventive Medicine. 23, 1, 1.

Research output: Contribution to journalArticle

Rural Population
Serum Albumin
Atherosclerosis
Oxidation-Reduction
Bromcresol Green
2017
4 Citations (Scopus)

HLA-DQ gene polymorphisms are associated with hepatocellular carcinoma and hepatitis B surface antigen in chronic hepatitis B virus infection

Ochi, Y., Hashimoto, S., Kawabe, N., Murao, M., Nakano, T., Kan, T., Nakaoka, K., Ohki, M., Kurashita, T., Takamura, T., Nomura, S., Nishikawa, T., Fukui, A., Osakabe, K., Ichino, N. & Yoshioka, K., 01-07-2017, In : Hepatology Research. 47, 8, p. 755-766 12 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Virus Diseases
Hepatitis B Surface Antigens
HLA Antigens
Hepatitis B virus
2015
5 Citations (Scopus)

Changes of shear-wave velocity by interferon-based therapy in chronic hepatitis C

Osakabe, K., Ichino, N., Nishikawa, T., Sugiyama, H., Kato, M., Shibata, A., Asada, W., Kawabe, N., Hashimoto, S., Murao, M., Nakano, T., Shimazaki, H., Kan, T., Nakaoka, K., Takagawa, Y., Ohki, M., Kurashita, T., Takamura, T. & Yoshioka, K., 21-09-2015, In : World Journal of Gastroenterology. 21, 35, p. 10215-10223 9 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Interferons
Therapeutics
Acoustics
Ribavirin
34 Citations (Scopus)

Longitudinal study of circulating miR-122 in a rat model of non-alcoholic fatty liver disease

Yamada, H., Ohashi, K., Suzuki, K., Munetsuna, E., Ando, Y., Yamazaki, M., Ishikawa, H., Ichino, N., Teradaira, R. & Hashimoto, S., 01-01-2015, In : Clinica Chimica Acta. 446, p. 267-271 5 p.

Research output: Contribution to journalArticle

Liver
Longitudinal Studies
Rats
Serum
Biomarkers
9 Citations (Scopus)

PNPLA3 I148M associations with liver carcinogenesis in Japanese chronic hepatitis C patients

Nakaoka, K., Hashimoto, S., Kawabe, N., Nitta, Y., Murao, M., Nakano, T., Shimazaki, H., Kan, T., Takagawa, Y., Ohki, M., Kurashita, T., Takamura, T., Nishikawa, T., Ichino, N., Osakabe, K. & Yoshioka, K., 01-01-2015, In : SpringerPlus. 4, 1

Research output: Contribution to journalArticle

Phospholipases
Chronic Hepatitis C
Carcinogenesis
Genotype
Liver
5 Citations (Scopus)

The NAFLD Index: A Simple and Accurate Screening Tool for the Prediction of Non-Alcoholic Fatty Liver Disease

Ichino, N., Osakabe, K., Sugimoto, K., Suzuki, K., Yamada, H., Takai, H., Sugiyama, H., Yukitake, J., Inoue, T., Ohashi, K., Hata, T., Hamajima, N., Nishikawa, T., Hashimoto, S., Kawabe, N. & Yoshioka, K., 01-01-2015, In : Rinsho byori. The Japanese journal of clinical pathology. 63, 1, p. 32-43 12 p.

Research output: Contribution to journalArticle

Non-alcoholic Fatty Liver Disease
Autoimmune Hepatitis
Chronic Hepatitis B
Chronic Hepatitis C
Developed Countries
2014
5 Citations (Scopus)

Association between serum levels of carotenoids and serum asymmetric dimethylarginine levels in Japanese subjects

Watarai, R., Suzuki, K., Ichino, N., Osakabe, K., Sugimoto, K., Yamada, H., Hamajima, T., Hamajima, N. & Inoue, T., 2014, In : Journal of epidemiology. 24, 3, p. 250-257 8 p.

Research output: Contribution to journalArticle

Carotenoids
Odds Ratio
Serum
Nitric Oxide Synthase
N,N-dimethylarginine
22 Citations (Scopus)

Factors correlating with acoustic radiation force impulse elastography in chronic hepatitis C

Nishikawa, T., Hashimoto, S., Kawabe, N., Harata, M., Nitta, Y., Murao, M., Nakano, T., Mizuno, Y., Shimazaki, H., Kan, T., Nakaoka, K., Takagawa, Y., Ohki, M., Ichino, N., Osakabe, K. & Yoshioka, K., 07-02-2014, In : World Journal of Gastroenterology. 20, 5, p. 1289-1297 9 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Chronic Hepatitis C
Acoustics
Fibrosis
Radiation
2013
5 Citations (Scopus)

Association of serum carotenoid levels with N-terminal pro-brain-type natriuretic peptide: A cross-sectional study in Japan

Suzuki, K., Ishii, J., Kitagawa, F., Kuno, A., Kusuhara, Y., Ochiai, J., Ichino, N., Osakabe, K., Sugimoto, K., Yamada, H., Ito, Y., Hamajima, N. & Inoue, T., 18-07-2013, In : Journal of epidemiology. 23, 3, p. 163-168 6 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Carotenoids
Japan
Cross-Sectional Studies
Serum
6 Citations (Scopus)

Association of serum carotenoid levels with urinary albumin excretion in a general Japanese population: The Yakumo study

Suzuki, K., Honjo, H., Ichino, N., Osakabe, K., Sugimoto, K., Yamada, H., Kusuhara, Y., Watarai, R., Hamajima, T., Hamajima, N. & Inoue, T., 31-08-2013, In : Journal of epidemiology. 23, 6, p. 451-456 6 p.

Research output: Contribution to journalArticle

Albuminuria
Carotenoids
Albumins
Serum
Population
136 Citations (Scopus)

Associations between circulating microRNAs (miR-21, miR-34a, miR-122 and miR-451) and non-alcoholic fatty liver

Yamada, H., Suzuki, K., Ichino, N., Ando, Y., Sawada, A., Osakabe, K., Sugimoto, K., Ohashi, K., Teradaira, R., Inoue, T., Hamajima, N. & Hashimoto, S., 03-09-2013, In : Clinica Chimica Acta. 424, p. 99-103 5 p.

Research output: Contribution to journalArticle

Fatty Liver
MicroRNAs
Liver
Serum
Biomarkers
2012
5 Citations (Scopus)

The stiffness parameter β assessed by an ultrasonic phase-locked echo-tracking system is associated with plaque formation in the common carotid artery

Ichino, N., Osakabe, K., Sugimoto, K., Yokoi, A., Inoue, T., Suzuki, K., Kusuhara, Y., Hamajima, N., Takai, H. & Hata, T., 01-01-2012, In : Journal of Medical Ultrasonics. 39, 1, p. 3-9 7 p.

Research output: Contribution to journalArticle

Common Carotid Artery
Ultrasonics
Independent Living
Vascular Stiffness
Ultrasonography
2011
23 Citations (Scopus)

Liver stiffness in extrahepatic cholestasis correlates positively with bilirubin and negatively with alanine aminotransferase

Harata, M., Hashimoto, S., Kawabe, N., Nitta, Y., Murao, M., Nakano, T., Arima, Y., Shimazaki, H., Ishikawa, T., Okumura, A., Ichino, N., Osakabe, K., Nishikawa, T. & Yoshioka, K., 01-05-2011, In : Hepatology Research. 41, 5, p. 423-429 7 p.

Research output: Contribution to journalArticle

Extrahepatic Cholestasis
Alanine Transaminase
Bilirubin
Liver
Hydrostatic Pressure
38 Citations (Scopus)

Reduction of liver stiffness by antiviral therapy in chronic hepatitis B

Osakabe, K., Ichino, N., Nishikawa, T., Sugiyama, H., Kato, M., Kitahara, S., Hashimoto, S., Kawabe, N., Harata, M., Nitta, Y., Murao, M., Nakano, T., Shimazaki, H., Arima, Y., Suzuki, K. & Yoshioka, K., 01-11-2011, In : Journal of Gastroenterology. 46, 11, p. 1324-1334 11 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Antiviral Agents
Liver
Fibrosis
Therapeutics
2010
19 Citations (Scopus)

A new index for non-invasive assessment of liver fibrosis

Ichino, N., Osakabe, K., Nishikawa, T., Sugiyama, H., Kato, M., Kitahara, S., Hashimoto, S., Kawabe, N., Harata, M., Nitta, Y., Murao, M., Nakano, T., Arima, Y., Shimazaki, H., Suzuki, K. & Yoshioka, K., 14-10-2010, In : World Journal of Gastroenterology. 16, 38, p. 4809-4816 8 p.

Research output: Contribution to journalArticle

Liver Cirrhosis
Fibrosis
Liver
Prothrombin Time
Chronic Hepatitis C
39 Citations (Scopus)

Reduction of liver stiffness by interferon treatment in the patients with chronic hepatitis C

Arima, Y., Kawabe, N., Hashimoto, S., Harata, M., Nitta, Y., Murao, M., Nakano, T., Shimazaki, H., Kobayashi, K., Ichino, N., Osakabe, K., Nishikawa, T., Okumura, A., Ishikawa, T. & Yoshioka, K., 01-04-2010, In : Hepatology Research. 40, 4, p. 383-392 10 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Interferons
Liver
Therapeutics
Fibrosis
2009
62 Citations (Scopus)

Liver stiffness measured by transient elastography correlates with fibrosis area in liver biopsy in patients with chronic hepatitis C

Nitta, Y., Kawabe, N., Hashimoto, S., Harata, M., Komura, N., Kobayashi, K., Arima, Y., Shimazaki, H., Nakano, T., Murao, M., Ichino, N., Osakabe, K., Aoki, H., Hosoe, Y., Sugiyama, H., Nishikawa, T. & Yoshioka, K., 07-07-2009, In : Hepatology Research. 39, 7, p. 675-684 10 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Chronic Hepatitis C
Fibrosis
Biopsy
Liver
2007

Expression levels of Egr-1 and Nur77 proteins in mouse brain are increased by withdrawal of nicotine

Yamada, K., Sawada, H., Nishii, K., Ichino, N., Hida, T., Nagao, S., Takahashi, H., Ishiguro, H. & Nagatsu, T., 01-12-2007, In : Biogenic Amines. 21, 4, p. 183-194 12 p.

Research output: Contribution to journalArticle

Nicotine
Brain
Cerebral Cortex
Genes
Proteins
2006
32 Citations (Scopus)

Association of abdominal obesity with decreased serum levels of carotenoids in a healthy Japanese population

Suzuki, K., Inoue, T., Hioki, R., Ochiai, J., Kusuhara, Y., Ichino, N., Osakabe, K., Hamajima, N. & Ito, Y., 01-10-2006, In : Clinical Nutrition. 25, 5, p. 780-789 10 p.

Research output: Contribution to journalArticle

Abdominal Obesity
Carotenoids
Serum
Odds Ratio
Population
4 Citations (Scopus)

Contrast-enhanced sonography of pancreatic ductal carcinoma using agent detection imaging

Ichino, N., Horiguchi, Y., Imai, H., Osakabe, K., Nishikawa, T., Sugita, Y., Utsugi, H., Togo, Y., Sawai, T. & Mizoguchi, Y., 01-03-2006, In : Journal of Medical Ultrasonics. 33, 1, p. 29-35 7 p.

Research output: Contribution to journalArticle

Pancreatic Ductal Carcinoma
Blood Vessels
Ultrasonography
Microbubbles
Perfusion
1 Citation (Scopus)

Increased expression of signal proteins in mouse brain by withdrawal of nicotine after chronic administration of the alkaloid

Yamada, K., Ichino, N., Nishii, K., Sawada, H., Hida, T. & Ishiguro, H., 01-12-2006, In : Biogenic Amines. 20, 3-4, p. 112-120 9 p.

Research output: Contribution to journalArticle

Nicotine
Alkaloids
Brain
Genes
Proteins
2005
3 Citations (Scopus)

Expression levels of Rab2, a G protein, and Bag-1, a Bcl-2 binding protein are controlled by withdrawal of nicotine from cultured pheochromocytoma PC12 cells

Yamada, K., Ishiguro, H., Ichino, N., Nishii, K., Sawada, H., Hida, T. & Nagatsu, T., 01-05-2005, In : Journal of Neural Transmission. 112, 5, p. 633-639 7 p.

Research output: Contribution to journalArticle

PC12 Cells
Pheochromocytoma
Nicotine
GTP-Binding Proteins
Carrier Proteins
2002
15 Citations (Scopus)

Increase of transcriptional levels of egr-1 and nur77 genes due to both nicotine treatment and withdrawal in pheochromocytoma cells

Ichino, N., Yamada, K., Nishii, K., Sawada, H., Nagatsu, T. & Ishiguro, H., 23-07-2002, In : Journal of Neural Transmission. 109, 7-8, p. 1015-1022 8 p.

Research output: Contribution to journalArticle

Pheochromocytoma
Nicotine
Genes
PC12 Cells
Proteins
2001
55 Citations (Scopus)

Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene

Ishiguro, H., Yamada, K., Sawada, H., Nishii, K., Ichino, N., Sawada, M., Kurosawa, Y., Matsushita, N., Kobayashi, K., Goto, J., Hashida, H., Masuda, N., Kanazawa, I. & Nagatsu, T., 15-08-2001, In : Journal of Neuroscience Research. 65, 4, p. 289-297 9 p.

Research output: Contribution to journalArticle

Huntington Disease
Genes
Exons
Glial Fibrillary Acidic Protein
Brain
2000
15 Citations (Scopus)

Characterization of the human NTAK gene structure and distribution of the isoforms for rat NTAK mRNA

Yamada, K., Ichino, N., Nishii, K., Sawada, H., Higashiyama, S., Ishiguro, H. & Nagatsu, T., 05-09-2000, In : Gene. 255, 1, p. 15-24 10 p.

Research output: Contribution to journalArticle

Protein Isoforms
Messenger RNA
Genes
Brain
Neuregulins
16 Citations (Scopus)

The Risk of Helicobacter Pylori Infection and Atrophic Gastritis from Food and Drink Intake: A Cross-sectional Study in Hokkaido, Japan

Ito, Y., Suzuki, K., Ichino, N., Imai, H., Sakaguchi, H., Hokama, M., Nishii, M. & Nakano, H., 01-01-2000, In : Asian Pacific Journal of Cancer Prevention. 1, 2, p. 147-156 10 p.

Research output: Contribution to journalArticle

Atrophic Gastritis
Helicobacter Infections
Helicobacter pylori
Japan
Cross-Sectional Studies
1999
13 Citations (Scopus)

Nicotine withdrawal up-regulates c-Fos transcription in pheochromocytoma cells

Ichino, N., Ishiguro, H., Yamada, K., Nishii, K., Sawada, H. & Nagatsu, T., 01-10-1999, In : Neuroscience Research. 35, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

Pheochromocytoma
Nicotine
Up-Regulation
Proto-Oncogene Proteins c-jun
fos Genes
1998
9 Citations (Scopus)
5' Flanking Region
DNA sequences
Phorbol Esters
Tetradecanoylphorbol Acetate
Mixed Function Oxygenases
4 Citations (Scopus)

Structure and function of a novel ErbB ligand, NTAK

Ishiguro, H., Higashiyama, S., Yamada, K., Ichino, N., Taniguchi, N. & Nagatsu, T., 11-12-1998, In : Japanese Journal of Psychopharmacology. 18, 4, p. 137-142 6 p.

Research output: Contribution to journalShort survey

Thymus Gland
Phosphotransferases
Ligands
Epidermal Growth Factor
Protein Isoforms
1997
65 Citations (Scopus)

A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4

Higashiyama, S., Horikawa, M., Yamada, K., Ichino, N., Nakano, N., Nakagawa, T., Miyagawa, J., Matsushita, N., Nagatsu, T., Taniguchi, N. & Ishiguro, H., 01-01-1997, In : Journal of Biochemistry. 122, 3, p. 675-680 6 p.

Research output: Contribution to journalArticle

Thymus
Epidermal Growth Factor
Thymus Gland
Brain
Phosphotransferases
17 Citations (Scopus)

Nicotine regulates mRNA level of tyrosine hydroxylase gene but not that of nicotinic acetylcholine receptor genes in PC12 cells

Ishiguro, H., Ichino, N., Yamada, K. & Nagatsu, T., 30-05-1997, In : Neuroscience Letters. 228, 1, p. 37-40 4 p.

Research output: Contribution to journalArticle

PC12 Cells
Nicotinic Receptors
Tyrosine 3-Monooxygenase
Nicotine
Messenger RNA