• 1599 Citations
  • 15 h-Index
19942004
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Research Output 1994 2004

  • 1599 Citations
  • 15 h-Index
  • 18 Article
2004
284 Citations (Scopus)

N-cadherin expression and epithelial-mesenchymal transition in pancreatic carcinoma

Nakajima, S., Doi, R., Toyoda, E., Tsuji, S., Wada, M., Koizumi, M., Tulachan, S. S., Ito, D., Kami, K., Mori, T., Kawaguchi, Y., Fujimoto, K., Hosotani, R. & Imamura, M., 15-07-2004, In : Clinical Cancer Research. 10, 12 I, p. 4125-4133 9 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Cadherins
Vimentin
Neoplasms
Intercellular Signaling Peptides and Proteins
2003
53 Citations (Scopus)

All-trans retinoic acid induces differentiation of ducts and endocrine cells by mesenchymal/epithelial interactions in embryonic pancreas

Singh Tulachan, S., Doi, R., Kawaguchi, Y., Tsuji, S., Nakajima, S., Masui, T., Koizumi, M., Toyoda, E., Mori, T., Ito, D., Kami, K., Fujimoto, K. & Imamura, M., 01-01-2003, In : Diabetes. 52, 1, p. 76-84 9 p.

Research output: Contribution to journalArticle

Endocrine Cells
Tretinoin
Pancreas
Retinaldehyde
Retinoic Acid Receptors
69 Citations (Scopus)

Endogenous decoy receptor 3 blocks the growth inhibition signals mediated by Fas ligand in human pancreatic adenocarcinoma

Tsuji, S., Hosotani, R., Yonehara, S., Masui, T., Tulachan, S. S., Nakajima, S., Kobayashi, H., Koizumi, M., Toyoda, E., Ito, D., Kami, K., Mori, T., Fujimoto, K., Doi, R. & Imamura, M., 10-08-2003, In : International Journal of Cancer. 106, 1, p. 17-25 9 p.

Research output: Contribution to journalArticle

Fas Ligand Protein
Pancreatic Neoplasms
Adenocarcinoma
Growth
Cell Line
113 Citations (Scopus)

RECK expression in pancreatic cancer: Its correlation with lower invasiveness and better prognosis

Masui, T., Doi, R., Koshiba, T., Fujimoto, K., Tsuji, S., Nakajima, S., Koizumi, M., Toyoda, E., Tulachan, S., Ito, D., Kami, K., Mori, T., Wada, M., Noda, M. & Imamura, M., 01-05-2003, In : Clinical Cancer Research. 9, 5, p. 1779-1784 6 p.

Research output: Contribution to journalArticle

Metalloproteases
Pancreatic Neoplasms
Neoplasms
Pancreatic Ductal Carcinoma
Suppressor Genes
2002
19 Citations (Scopus)

Antiproliferative activity induced by the somatostatin analogue, TT-232, in human pancreatic cancer cells

Lee, J. U., Hosotani, R., Wada, M., Doi, R., Koshiba, T., Fujimoto, K., Miyamoto, Y., Tsuji, S., Nakajima, S., Hirohashi, M., Uehara, T., Arano, Y., Fujii, N. & Imamura, M., 22-07-2002, In : European Journal of Cancer. 38, 11, p. 1526-1534 9 p.

Research output: Contribution to journalArticle

Somatostatin
Pancreatic Neoplasms
Protein Tyrosine Phosphatases
Growth
Binding Sites
22 Citations (Scopus)

Expression of IL-6 receptor in pancreatic cancer: Involvement in VEGF induction

Masui, T., Hosotani, R., Doi, R., Miyamoto, Y., Tsuji, S., Nakajima, S., Kobayashi, H., Koizumi, M., Toyoda, E., Tulachan, S. S. & Imamura, M., 01-11-2002, In : Anticancer research. 22, 6 C, p. 4093-4100 8 p.

Research output: Contribution to journalArticle

Interleukin-6 Receptors
Pancreatic Neoplasms
Vascular Endothelial Growth Factor A
Interleukin-6
Angiogenesis Inducing Agents
2001
23 Citations (Scopus)

A novel synthetic Arg-Gly-Asp-containing peptide cyclo(-RGDf=V-) is the potent inhibitor of angiogenesis

Kawaguchi, M., Hosotani, R., Ohishi, S., Fujii, N., Singh Tulachan, S., Koizumi, M., Toyoda, E., Masui, T., Nakajima, S., Tsuji, S., Ida, J., Fujimoto, K., Wada, M., Doi, R. & Imamura, M., 02-11-2001, In : Biochemical and Biophysical Research Communications. 288, 3, p. 711-717 7 p.

Research output: Contribution to journalArticle

Angiogenesis Inhibitors
Integrins
Cyclic Peptides
Peptides
Human Umbilical Vein Endothelial Cells
80 Citations (Scopus)

Expression of METH-1 and METH-2 in pancreatic cancer

Masui, T., Hosotani, R., Tsuji, S., Miyamoto, Y., Yasuda, S., Ida, J., Nakajima, S., Kawaguchi, M., Kobayashi, H., Koizumi, M., Toyoda, E., Tulachan, S., Arii, S., Doi, R. & Imamura, M., 28-11-2001, In : Clinical Cancer Research. 7, 11, p. 3437-3443 7 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Hepatocellular Carcinoma
Pancreas
Messenger RNA
Lymph Nodes
51 Citations (Scopus)

Interleukin-6 inhibits radiation induced apoptosis in pancreatic cancer cells

Miyamoto, Y., Hosotani, R., Doi, R., Wada, M., Ida, J., Tsuji, S., Kawaguchi, M., Nakajima, S., Kobayashi, H., Masui, T. & Imamura, M., 24-11-2001, In : Anticancer research. 21, 4 A, p. 2449-2456 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Interleukin-6
Radiation
Apoptosis
Interleukin-6 Receptors
2000
15 Citations (Scopus)

Auto-induction and growth stimulatory effect of betacellulin in human pancreatic cancer cells.

Kawaguchi, M., Hosotani, R., Kogire, M., Ida, J., Doi, R., Koshiba, T., Miyamoto, Y., Tsuji, S., Nakajima, S., Kobayashi, H., Masui, T. & Imamura, M., 01-2000, In : International journal of oncology. 16, 1, p. 37-41 5 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Growth
Epidermal Growth Factor
Betacellulin
Epidermal Growth Factor Receptor
394 Citations (Scopus)

Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: A possible role for tumor progression

Koshiba, T., Hosotani, R., Miyamoto, Y., Ida, J., Tsuji, S., Nakajima, S., Kawaguchi, M., Kobayashi, H., Doi, R., Hori, T., Fujii, N. & Imamura, M., 26-09-2000, In : Clinical Cancer Research. 6, 9, p. 3530-3535 6 p.

Research output: Contribution to journalArticle

CXCR4 Receptors
Chemokine CXCL12
Pancreatic Neoplasms
Ligands
Neoplasms
10 Citations (Scopus)

Immunohistochemical analysis of apoptosis-related proteins in human embryonic and fetal pancreatic tissues

Kobayashi, H., Doi, R., Hosotani, R., Miyamoto, Y., Koshiba, T., Fujimoto, K., Ida, J., Tsuji, S., Nakajima, S., Kawaguchi, M., Shiota, K. & Imamura, M., 26-06-2000, In : International Journal of Pancreatology. 27, 2, p. 113-122 10 p.

Research output: Contribution to journalArticle

Fetus
Apoptosis
Pancreas
Proteins
Proliferating Cell Nuclear Antigen
1999
138 Citations (Scopus)

Immunohistochemical analysis of Bcl-2, Bax, Bcl-X, and Mcl-1 expression in pancreatic cancers

Miyamoto, Y., Hosotani, R., Wada, M., Lee, J. U., Koshiba, T., Fujimoto, K., Tsuji, S., Nakajima, S., Doi, R., Kato, M., Shimada, Y. & Imamura, M., 01-01-1999, In : Oncology. 56, 1, p. 73-82 10 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Papillary Adenocarcinoma
Mucinous Adenocarcinoma
Adenocarcinoma
Cell Line
70 Citations (Scopus)

Immunohistochemical analysis of cyclooxygenase-2 expression in pancreatic tumors

Koshiba, T., Hosotani, R., Miyamoto, Y., Wada, M., Lee, J. U., Fujimoto, K., Tsuji, S., Nakajima, S., Doi, R. & Imamura, M., 09-12-1999, In : International Journal of Pancreatology. 26, 2, p. 69-76 8 p.

Research output: Contribution to journalArticle

Cyclooxygenase 2
Pancreatic Neoplasms
Mucinous Adenocarcinoma
Neoplasms
Papillary Adenocarcinoma
65 Citations (Scopus)

Induction of cell-cycle arrest and apoptosis by a novel retinobenzoic- acid derivative, TAC-101, in human pancreatic-cancer cells

Fujimoto, K., Hosotani, R., Doi, R., Wada, M., Lee, J. U., Koshiba, T., Miyamoto, Y., Tsuji, S., Nakajima, S. & Imamura, M., 10-05-1999, In : International Journal of Cancer. 81, 4, p. 637-644 8 p.

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
Pancreatic Neoplasms
Apoptosis
Acids
G1 Phase
1998
23 Citations (Scopus)

An exogenous cdk inhibitor, butyrolactone-I, induces apoptosis with increased Bax/Bcl-2 ratio in p53-mutated pancreatic cancer cells

Wada, M., Hosotani, R., Lee, J. U., Doi, R., Koshiba, T., Fujimoto, K., Miyamoto, Y., Tsuji, S., Nakajima, S., Okuyama, A. & Imamura, M., 01-07-1998, In : Anticancer research. 18, 4 A, p. 2559-2566 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Apoptosis
In Situ Nick-End Labeling
Cyclin A
Growth
156 Citations (Scopus)

Expression of two angiogenic factors, vascular endothelial growth factor and platelet-derived endothelial cell growth factor in human pancreatic cancer, and its relationship to angiogenesis

Fujimoto, K., Hosotani, R., Wada, M., Lee, J. U., Koshiba, T., Miyamoto, Y., Tsuji, S., Nakajima, S., Doi, R. & Imamura, M., 01-08-1998, In : European Journal of Cancer. 34, 9, p. 1439-1447 9 p.

Research output: Contribution to journalArticle

Thymidine Phosphorylase
Angiogenesis Inducing Agents
Pancreatic Neoplasms
Vascular Endothelial Growth Factor A
Microvessels
1994
14 Citations (Scopus)

Typical fibrolamellar hepatocellular carcinoma in Japanese patients: Report of two cases

Tanaka, J., Baba, N., Arii, S., Fujita, K. I., Tamura, J., Kawakami, Y., Tsuji, S., Imamura, M., Yamabe, H., Nakai, S. & Tobe, T., 01-05-1994, In : Surgery Today. 24, 5, p. 459-463 5 p.

Research output: Contribution to journalArticle

Virus Diseases
Liver
Hepatitis C
Hepatitis B
Histology