• 25096 Citations
  • 76 h-Index
1973 …2020

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Article
2020

Generation and analysis of novel Reln-deleted mouse model corresponding to exonic Reln deletion in schizophrenia

Sawahata, M., Mori, D., Arioka, Y., Kubo, H., Kushima, I., Kitagawa, K., Sobue, A., Shishido, E., Sekiguchi, M., Kodama, A., Ikeda, R., Aleksic, B., Kimura, H., Ishizuka, K., Nagai, T., Kaibuchi, K., Nabeshima, T., Yamada, K. & Ozaki, N., 01-01-2020, (Accepted/In press) In : Psychiatry and clinical neurosciences.

Research output: Contribution to journalArticle

Open Access

Indoleamine-2,3-dioxygenase-1 is a molecular target for the protective activity of mood stabilizers against mania-like behavior induced by d-amphetamine

Tran, H. Q., Shin, E. J., Saito, K., Tran, T. V., Phan, D. H., Sharma, N., Kim, D. W., Choi, S. Y., Jeong, J. H., Jang, C. G., Cheong, J. H., Nabeshima, T. & Kim, H. C., 02-2020, In : Food and Chemical Toxicology. 136, 110986.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Organophosphate Agent Induces ADHD-Like Behaviors via Inhibition of Brain Endocannabinoid-Hydrolyzing Enzyme(s) in Adolescent Male Rats

Ito, Y., Tomizawa, M., Suzuki, K., Shirakawa, Y., Ono, H., Adachi, K., Suzuki, H., Shimomura, K., Nabeshima, T. & Kamijima, M., 26-02-2020, In : Journal of Agricultural and Food Chemistry. 68, 8, p. 2547-2553 7 p.

Research output: Contribution to journalArticle

Serum Metabolic Profiles of the Tryptophan-Kynurenine Pathway in the high risk subjects of major depressive disorder

Sakurai, M., Yamamoto, Y., Kanayama, N., Hasegawa, M., Mouri, A., Takemura, M., Matsunami, H., Miyauchi, T., Tokura, T., Kimura, H., Ito, M., Umemura, E., Boku, A. S., Nagashima, W., Tonoike, T., Kurita, K., Ozaki, N., Nabeshima, T. & Saito, K., 01-12-2020, In : Scientific reports. 10, 1, 1961.

Research output: Contribution to journalArticle

Open Access
2019

5-HT 1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox

Tran, H. Q., Shin, E. J., Hoai Nguyen, B. C., Phan, D. H., Kang, M. J., Jang, C. G., Jeong, J. H., Nah, S. Y., Mouri, A., Saito, K., Nabeshima, T. & Kim, H. C., 01-01-2019, In : Food and Chemical Toxicology. 123, p. 125-141 17 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Acute administration of ketamine attenuates the impairment of social behaviors induced by social defeat stress exposure as juveniles via activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors

Hasegawa, S., Yoshimi, A., Mouri, A., Uchida, Y., Hida, H., Mishina, M., Yamada, K., Ozaki, N., Nabeshima, T. & Noda, Y., 04-2019, In : Neuropharmacology. 148, p. 107-116 10 p.

Research output: Contribution to journalArticle

Association of lifelong intake of barley diet with healthy aging: Changes in physical and cognitive functions and intestinal microbiome in senescence-accelerated mouse-prone 8 (samp8)

Shimizu, C., Wakita, Y., Kihara, M., Kobayashi, N., Tsuchiya, Y. & Nabeshima, T., 08-2019, In : Nutrients. 11, 8, 1770.

Research output: Contribution to journalArticle

Open Access

Astrocytic mobilization of glutathione peroxidase-1 contributes to the protective potential against cocaine kindling behaviors in mice via activation of JAK2/STAT3 signaling

Mai, H. N., Nguyen, L. T. T., Shin, E. J., Kim, D. J., Jeong, J. H., Chung, Y. H., Lei, X. G., Sharma, N., Jang, C. G., Nabeshima, T. & Kim, H. C., 01-02-2019, In : Free Radical Biology and Medicine. 131, p. 408-431 24 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms

Teshigawara, T., Mouri, A., Kubo, H., Nakamura, Y., Shiino, T., Okada, T., Morikawa, M., Nabeshima, T., Ozaki, N., Yamamoto, Y. & Saito, K., 01-08-2019, In : Journal of Affective Disorders. 255, p. 168-176 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
3 Citations (Scopus)

Effects of lifelong intake of lemon polyphenols on aging and intestinal microbiome in the senescence-accelerated mouse prone 1 (SAMP1)

Shimizu, C., Wakita, Y., Inoue, T., Hiramitsu, M., Okada, M., Mitani, Y., Segawa, S., Tsuchiya, Y. & Nabeshima, T., 01-12-2019, In : Scientific reports. 9, 1, 3671.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Indoleamine 2,3-dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma

Yamasuge, W., Yamamoto, Y., Fujigaki, H., Hoshi, M., Nakamoto, K., Kunisawa, K., Mouri, A., Nabeshima, T. & Saito, K., 01-10-2019, In : Cancer science. 110, 10, p. 3061-3067 7 p.

Research output: Contribution to journalArticle

Open Access

Lithium attenuates d-amphetamine-induced hyperlocomotor activity in mice via inhibition of interaction between cyclooxygenase-2 and indoleamine-2,3-dioxygenase

Phan, D. H., Shin, E. J., Jeong, J. H., Tran, H. Q., Sharma, N., Nguyen, B. T., Jung, T. W., Nah, S. Y., Saito, K., Nabeshima, T. & Kim, H. C., 01-01-2019, (Accepted/In press) In : Clinical and Experimental Pharmacology and Physiology.

Research output: Contribution to journalArticle

Mice deficient in protein tyrosine phosphatase receptor type Z (PTPRZ) show reduced responsivity to methamphetamine despite an enhanced response to novelty

Fujikawa, A., Noda, Y., Yamamoto, H., Tanga, N., Sakaguchi, G., Hattori, S., Song, W. J., Sora, I., Nabeshima, T., Katsuura, G. & Noda, M., 01-01-2019, In : PloS one. 14, 8, e0221205.

Research output: Contribution to journalArticle

Open Access

Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues

Yoshida, Y., Fujigaki, H., Kato, K., Yamazaki, K., Fujigaki, S., Kunisawa, K., Yamamoto, Y., Mouri, A., Oda, A., Nabeshima, T. & Saito, K., 01-12-2019, In : Scientific reports. 9, 1, 10243.

Research output: Contribution to journalArticle

Open Access

Theanine attenuates memory impairments induced by: Klotho gene depletion in mice

Nguyen, B. T., Sharma, N., Shin, E. J., Jeong, J. H., Lee, S. H., Jang, C. G., Nah, S. Y., Nabeshima, T., Yoneda, Y. & Kim, H. C., 01-2019, In : Food and Function. 10, 1, p. 325-332 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes

Sobue, A., Ito, N., Nagai, T., Shan, W., Hada, K., Nakajima, A., Murakami, Y., Mouri, A., Yamamoto, Y., Nabeshima, T., Saito, K. & Yamada, K., 05-2018, In : GLIA. 66, 5, p. 1034-1052 19 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Blockade of platelet-activating factor receptor attenuates abnormal behaviors induced by phencyclidine in mice through down-regulation of NF-κB

Tran, T. V., Park, S. J., Shin, E. J., Tran, H. Q., Jeong, J. H., Jang, C. G., Lee, Y. J., Nah, S. Y., Nabeshima, T. & Kim, H. C., 01-03-2018, In : Brain Research Bulletin. 137, p. 71-78 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Cell type-specific activation of mitogen-activated protein kinase in D1 receptor-expressing neurons of the nucleus accumbens potentiates stimulus-reward learning in mice

Bin Saifullah, M. A., Nagai, T., Kuroda, K., Wulaer, B., Nabeshima, T., Kaibuchi, K. & Yamada, K., 01-12-2018, In : Scientific reports. 8, 1, 14413.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Cerebellar α 6 -subunit-containing GABA A receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders

Chiou, L. C., Lee, H. J., Ernst, M., Huang, W. J., Chou, J. F., Chen, H. L., Mouri, A., Chen, L. C., Treven, M., Mamiya, T., Fan, P. C., Knutson, D. E., Witzigmann, C., Cook, J., Sieghart, W. & Nabeshima, T., 06-2018, In : British Journal of Pharmacology. 175, 12, p. 2414-2427 14 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Clozapine attenuates mitochondrial burdens and abnormal behaviors elicited by phencyclidine in mice via inhibition of p47 phox ; Possible involvements of phosphoinositide 3-kinase/Akt signaling

Tran, H. Q., Park, S. J., Shin, E. J., Tran, T. V., Sharma, N., Lee, Y. J., Jeong, J. H., Jang, C. G., Kim, D. J., Nabeshima, T. & Kim, H. C., 01-11-2018, In : Journal of Psychopharmacology. 32, 11, p. 1233-1251 19 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Dysfunction of serotonergic and dopaminergic neuronal systems in the antidepressant-resistant impairment of social behaviors induced by social defeat stress exposure as juveniles

Hasegawa, S., Miyake, Y., Yoshimi, A., Mouri, A., Hida, H., Yamada, K., Ozaki, N., Nabeshima, T. & Noda, Y., 01-01-2018, In : International Journal of Neuropsychopharmacology. 21, 9, p. 837-846 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effects of oral calcium dosage and timing on ethanol-induced sensitization of locomotion in DBA/2 mice

Shimizu, C., Mitani, Y., Tsuchiya, Y. & Nabeshima, T., 01-01-2018, In : Biological and Pharmaceutical Bulletin. 41, 7, p. 1049-1061 13 p.

Research output: Contribution to journalArticle

EŠect of non-alcoholic beverage intake in children on alcoholic beverage drinking and smoking

Goto, A., Yanamoto, K., Yoshimi, A., Nabeshima, T. & Noda, Y., 01-01-2018, In : Yakugaku Zasshi. 138, 7, p. 963-971 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Exposure to far-infrared ray attenuates methamphetamine-induced impairment in recognition memory through inhibition of protein kinase C δ in male mice: Comparison with the antipsychotic clozapine

Mai, H. N., Sharma, N., Shin, E. J., Nguyen, B. T., Nguyen, P. T., Jeong, J. H., Cho, E. H., Lee, Y. J., Kim, N. H., Jang, C. G., Nabeshima, T. & Kim, H. C., 07-2018, In : Journal of Neuroscience Research. 96, 7, p. 1294-1310 17 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Exposure to Far Infrared Ray Protects Methamphetamine-Induced Behavioral Sensitization in Glutathione Peroxidase-1 Knockout Mice via Attenuating Mitochondrial Burdens and Dopamine D1 Receptor Activation

Mai, H. N., Sharma, N., Shin, E. J., Nguyen, B. T., Jeong, J. H., Jang, C. G., Cho, E. H., Nah, S. Y., Kim, N. H., Nabeshima, T. & Kim, H. C., 01-05-2018, In : Neurochemical Research. 43, 5, p. 1118-1135 18 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Exposure to far-infrared rays attenuates methamphetamine-induced recognition memory impairment via modulation of the muscarinic M1 receptor, Nrf2, and PKC

Mai, H. N., Sharma, N., Shin, E. J., Nguyen, B. T., Nguyen, P. T., Jeong, J. H., Jang, C. G., Cho, E. H., Nah, S. Y., Kim, N. H., Nabeshima, T. & Kim, H. C., 01-06-2018, In : Neurochemistry International. 116, p. 63-76 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia

Sobue, A., Kushima, I., Nagai, T., Shan, W., Kohno, T., Aleksic, B., Aoyama, Y., Mori, D., Arioka, Y., Kawano, N., Yamamoto, M., Hattori, M., Nabeshima, T., Yamada, K. & Ozaki, N., 01-12-2018, In : Scientific reports. 8, 1, 13046.

Research output: Contribution to journalArticle

6 Citations (Scopus)

IL-6 knockout mice are protected from cocaine-induced kindling behaviors; possible involvement of JAK2/STAT3 and PACAP signalings

Mai, H. N., Chung, Y. H., Shin, E. J., Sharma, N., Jeong, J. H., Jang, C. G., Saito, K., Nabeshima, T., Reglodi, D. & Kim, H. C., 01-06-2018, In : Food and Chemical Toxicology. 116, p. 249-263 15 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Innate immune activation of astrocytes impairs neurodevelopment via upregulation of follistatin-like 1 and interferon-induced transmembrane protein 3

Yamada, S., Itoh, N., Nagai, T., Nakai, T., Ibi, D., Nakajima, A., Nabeshima, T. & Yamada, K., 22-10-2018, In : Journal of Neuroinflammation. 15, 1, 295.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Juvenile social defeat stress exposure persistently impairs social behaviors and neurogenesis

Mouri, A., Ukai, M., Uchida, M., Hasegawa, S., Taniguchi, M., Ito, T., Hida, H., Yoshimi, A., Yamada, K., Kunimoto, S., Ozaki, N., Nabeshima, T. & Noda, Y., 01-05-2018, In : Neuropharmacology. 133, p. 23-37 15 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2 Citations (Scopus)

Neuronal PAS domain protein 4 (Npas4) controls neuronal homeostasis in pentylenetetrazole-induced epilepsy through the induction of Homer1a

Shan, W., Nagai, T., Tanaka, M., Itoh, N., Furukawa-Hibi, Y., Nabeshima, T., Sokabe, M. & Yamada, K., 04-2018, In : Journal of neurochemistry. 145, 1, p. 19-33 15 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

PKCδ-dependent p47phox activation mediates methamphetamine-induced dopaminergic neurotoxicity

Dang, D. K., Shin, E. J., Kim, D. J., Tran, H. Q., Jeong, J. H., Jang, C. G., Ottersen, O. P., Nah, S. Y., Hong, J. S., Nabeshima, T. & Kim, H. C., 01-02-2018, In : Free Radical Biology and Medicine. 115, p. 318-337 20 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

PKCδ Knockout Mice Are Protected from Dextromethorphan-Induced Serotonergic Behaviors in Mice: Involvements of Downregulation of 5-HT1A Receptor and Upregulation of Nrf2-Dependent GSH Synthesis

Tran, H. Q., Lee, Y., Shin, E. J., Jang, C. G., Jeong, J. H., Mouri, A., Saito, K., Nabeshima, T. & Kim, H. C., 01-10-2018, In : Molecular Neurobiology. 55, 10, p. 7802-7821 20 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Protein Kinase Cδ Gene Depletion Protects Against Methamphetamine-Induced Impairments in Recognition Memory and ERK1/2 Signaling via Upregulation of Glutathione Peroxidase-1 Gene

Tran, T. V., Shin, E. J., Nguyen, L. T. T., Lee, Y., Kim, D. J., Jeong, J. H., Jang, C. G., Nah, S. Y., Toriumi, K., Nabeshima, T., Yamada, K. & Kim, H. C., 01-05-2018, In : Molecular Neurobiology. 55, 5, p. 4136-4159 24 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Repetitive and compulsive-like behaviors lead to cognitive dysfunction in Disc1Δ2-3/Δ2-3 mice

Wulaer, B., Nagai, T., Sobue, A., Itoh, N., Kuroda, K., Kaibuchi, K., Nabeshima, T. & Yamada, K., 11-2018, In : Genes, Brain and Behavior. 17, 8, e12478.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Role of dopamine D1 receptor in 3-fluoromethamphetamine-induced neurotoxicity in mice

Nguyen, P. T., Shin, E. J., Dang, D. K., Tran, H. Q., Jang, C. G., Jeong, J. H., Lee, Y. J., Lee, H. J., Lee, Y. S., Yamada, K., Nabeshima, T. & Kim, H. C., 01-02-2018, In : Neurochemistry International. 113, p. 69-84 16 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Role of Mitochondria in Methamphetamine-Induced Dopaminergic Neurotoxicity: Involvement in Oxidative Stress, Neuroinflammation, and Pro-apoptosis—A Review

Shin, E. J., Tran, H. Q., Nguyen, P. T., Jeong, J. H., Nah, S. Y., Jang, C. G., Nabeshima, T. & Kim, H. C., 01-01-2018, In : Neurochemical Research. 43, 1, p. 57-69 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Shati/Nat8l knockout mice show behavioral deficits ameliorated by atomoxetine and methylphenidate

Toriumi, K., Tanaka, J., Mamiya, T., Alkam, T., Kim, H. C., Nitta, A. & Nabeshima, T., 26-02-2018, In : Behavioural Brain Research. 339, p. 207-214 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice

Kubo, H., Hoshi, M., Mouri, A., Tashita, C., Yamamoto, Y., Nabeshima, T. & Saito, K., 01-01-2017, In : Immunology Letters. 181, p. 94-100 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Adolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable mice

Matsumoto, Y., Niwa, M., Mouri, A., Noda, Y., Fukushima, T., Ozaki, N. & Nabeshima, T., 01-10-2017, In : Psychopharmacology. 234, 20, p. 3055-3074 20 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Behavioral impairment in SHATI/NAT8L knockout mice via dysfunction of myelination development

Sumi, K., Uno, K., Noike, H., Tomohiro, T., Hatanaka, Y., Furukawa-Hibi, Y., Nabeshima, T., Miyamoto, Y. & Nitta, A., 01-12-2017, In : Scientific reports. 7, 1, 16872.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Betaine attenuates memory impairment after water-immersion restraint stress and is regulated by the GABAergic neuronal system in the hippocampus

Kunisawa, K., Kido, K., Nakashima, N., Matsukura, T., Nabeshima, T. & Hiramatsu, M., 01-01-2017, In : European Journal of Pharmacology. 796, p. 122-130 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Genetic or pharmacological depletion of cannabinoid CB1 receptor protects against dopaminergic neurotoxicity induced by methamphetamine in mice

Dang, D. K., Shin, E. J., Mai, A. T., Jang, C. G., Nah, S. Y., Jeong, J. H., Ledent, C., Yamamoto, T., Nabeshima, T., Onaivi, E. S. & Kim, H. C., 01-07-2017, In : Free Radical Biology and Medicine. 108, p. 204-224 21 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Ginsenoside Re protects against phencyclidine-induced behavioral changes and mitochondrial dysfunction via interactive modulation of glutathione peroxidase-1 and NADPH oxidase in the dorsolateral cortex of mice

Tran, T. V., Shin, E. J., Dang, D. K., Ko, S. K., Jeong, J. H., Nah, S. Y., Jang, C. G., Lee, Y. J., Toriumi, K., Nabeshima, T. & Kim, H. C., 01-12-2017, In : Food and Chemical Toxicology. 110, p. 300-315 16 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions

Tashiro, T., Murakami, Y., Mouri, A., Imamura, Y., Nabeshima, T., Yamamoto, Y. & Saito, K., 15-01-2017, In : Behavioural Brain Research. 317, p. 279-285 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

MK-801, but not naloxone, attenuates high-dose dextromethorphan-induced convulsive behavior: Possible involvement of the GluN2B receptor

Tran, H. Q., Chung, Y. H., Shin, E. J., Tran, T. V., Jeong, J. H., Jang, C. G., Nah, S. Y., Yamada, K., Nabeshima, T. & Kim, H. C., 01-11-2017, In : Toxicology and Applied Pharmacology. 334, p. 158-166 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Prenatal nicotine exposure decreases the release of dopamine in the medial frontal cortex and induces atomoxetine-responsive neurobehavioral deficits in mice

Alkam, T., Mamiya, T., Kimura, N., Yoshida, A., Kihara, D., Tsunoda, Y., Aoyama, Y., Hiramatsu, M., Kim, H. C. & Nabeshima, T., 01-06-2017, In : Psychopharmacology. 234, 12, p. 1853-1869 17 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)