• 1231 Citations
  • 20 h-Index
20022020

Research output per year

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Research Output

  • 1231 Citations
  • 20 h-Index
  • 58 Article
  • 1 Comment/debate
  • 1 Review article
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Article
2020

Changes in Serum Immunoglobulin G4 Levels in Patients with Newly Diagnosed Graves' Disease

Hiratsuka, I., Yamada, H., Itoh, M., Shibata, M., Takayanagi, T., Makino, M., Sugimura, Y., Hayakawa, N., Hashimoto, S. & Suzuki, A., 01-01-2020, In : Experimental and Clinical Endocrinology and Diabetes. 128, 2, p. 119-124 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Diagnosis and treatment of autoimmune and IgG4-related hypophysitis: Clinical guidelines of the Japan endocrine society

Takagi, H., Iwama, S., Sugimura, Y., Takahashi, Y., Oki, Y., Akamizu, T. & Arima, H., 01-01-2020, In : endocrine journal. 67, 4, p. 373-378 6 p.

Research output: Contribution to journalArticle

Open Access
2019

Low-carbohydrate diet by staple change attenuates postprandial GIP and CPR levels in type 2 diabetes patients

Kondo-Ando, M., Seino, Y., Morikawa, R., Negi, K., Todoroki, H., Kawakami, T., Asada, Y., Yoshimoto, R., Tanaka, C., Okamoto, K., Masuda, A., Tomatsu, E., Hiratsuka, I., Yoshino, Y., Maki, W., Kakita, A., Shibata, M., Takayanagi, T., Makino, M., Sugimura, Y. & 7 others, Asai, S., Ito, A., Ueno, S., Fujiwara, Y., Kuwata, H., Yabe, D. & Suzuki, A., 11-2019, In : Journal of Diabetes and its Complications. 33, 11, 107415.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Risedronate Attenuates Podocyte Injury in Phosphate Transporter-Overexpressing Rats

Asada, Y., Takayanagi, T., Kawakami, T., Tomatsu, E., Masuda, A., Yoshino, Y., Sekiguchi-Ueda, S., Shibata, M., Ide, T., Niimi, H., Yaoita, E., Seino, Y., Sugimura, Y. & Suzuki, A., 01-01-2019, In : International Journal of Endocrinology. 2019, 4194853.

Research output: Contribution to journalArticle

Open Access

Short-term high-starch, low-protein diet induces reversible increase in β-cell mass independent of body weight gain in mice

Masuda, A., Seino, Y., Murase, M., Hidaka, S., Shibata, M., Takayanagi, T., Sugimura, Y., Hayashi, Y. & Suzuki, A., 05-2019, In : Nutrients. 11, 5, 1045.

Research output: Contribution to journalArticle

Open Access
2018

Critical role of rabphilin-3A in the pathophysiology of experimental lymphocytic neurohypophysitis

Yasuda, Y., Iwama, S., Kiyota, A., Izumida, H., Nakashima, K., Iwata, N., Ito, Y., Morishita, Y., Goto, M., Suga, H., Banno, R., Enomoto, A., Takahashi, M., Arima, H. & Sugimura, Y., 04-2018, In : Journal of Pathology. 244, 4, p. 469-478 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Cullin-associated NEDD8-dissociated protein 1, a novel interactor of rabphilin-3A, deubiquitylates rabphilin-3A and regulates arginine vasopressin secretion in PC12 cells

Nakashima, K., Takeuchi, S., Iwama, S., Kiyota, A., Yasuda, Y., Iwata, N., Enomoto, A., Arima, H. & Sugimura, Y., 01-01-2018, In : endocrine journal. 65, 3, p. 325-334 10 p.

Research output: Contribution to journalArticle

Vasopressin-secreting neurons derived from human embryonic stem cells through specific induction of dorsal hypothalamic progenitors

Ogawa, K., Suga, H., Ozone, C., Sakakibara, M., Yamada, T., Kano, M., Mitsumoto, K., Kasai, T., Kodani, Y., Nagasaki, H., Yamamoto, N., Hagiwara, D., Goto, M., Banno, R., Sugimura, Y. & Arima, H., 01-12-2018, In : Scientific reports. 8, 1, 3615.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2017

Anti-pituitary antibodies against corticotrophs in IgG4-related hypophysitis

Iwata, N., Iwama, S., Sugimura, Y., Yasuda, Y., Nakashima, K., Takeuchi, S., Hagiwara, D., Ito, Y., Suga, H., Goto, M., Banno, R., Caturegli, P., Koike, T., Oshida, Y. & Arima, H., 01-06-2017, In : Pituitary. 20, 3, p. 301-310 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia

Tsunekawa, T., Banno, R., Mizoguchi, A., Sugiyama, M., Tominaga, T., Onoue, T., Hagiwara, D., Ito, Y., Iwama, S., Goto, M., Suga, H., Sugimura, Y. & Arima, H., 01-02-2017, In : EBioMedicine. 16, p. 172-183 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

NMDA receptor antagonist prevents cell death in the hippocampal dentate gyrus induced by hyponatremia accompanying adrenal insufficiency in rats

Izumida, H., Takagi, H., Fujisawa, H., Iwata, N., Nakashima, K., Takeuchi, S., Iwama, S., Namba, T., Komatu, Y., Kaibuchi, K., Oiso, Y., Arima, H. & Sugimura, Y., 01-01-2017, In : Experimental Neurology. 287, p. 65-74 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Rapid exacerbation of lymphocytic infundibuloneurohypophysitis

Shibue, K., Fujii, T., Goto, H., Yamashita, Y., Sugimura, Y., Tanji, M., Yasoda, A. & Inagaki, N., 01-03-2017, In : Medicine (United States). 96, 9, e6034.

Research output: Contribution to journalArticle

2016

AgRP neuron-specific deletion of glucocorticoid receptor leads to increased energy expenditure and decreased body weight in female mice on a high-fat diet

Shibata, M., Banno, R., Sugiyama, M., Tominaga, T., Onoue, T., Tsunekawa, T., Azuma, Y., Hagiwara, D., Lu, W., Ito, Y., Goto, M., Suga, H., Sugimura, Y., Oiso, Y. & Arima, H., 04-2016, In : Endocrinology. 157, 4, p. 1457-1466 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Chronic hyponatremia causes neurologic and psychologic impairments

Fujisawa, H., Sugimura, Y., Takagi, H., Mizoguchi, H., Takeuchi, H., Izumida, H., Nakashima, K., Ochiai, H., Takeuchi, S., Kiyota, A., Fukumoto, K., Iwama, S., Takagishi, Y., Hayashi, Y., Arima, H., Komatsu, Y., Murata, Y. & Oiso, Y., 03-2016, In : Journal of the American Society of Nephrology. 27, 3, p. 766-780 15 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Reactive oxygen species mediate insulin signal transduction in mouse hypothalamus

Onoue, T., Goto, M., Tominaga, T., Sugiyama, M., Tsunekawa, T., Hagiwara, D., Banno, R., Suga, H., Sugimura, Y. & Arima, H., 21-04-2016, In : Neuroscience Letters. 619, p. 1-7 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Tomosyn negatively regulates arginine vasopressin secretion in embryonic stem cell-derived neurons

Takeuchi, S., Iwama, S., Takagi, H., Kiyota, A., Nakashima, K., Izumida, H., Fujisawa, H., Iwata, N., Suga, H., Watanabe, T., Kaibuchi, K., Oiso, Y., Arima, H. & Sugimura, Y., 10-2016, In : PloS one. 11, 10, e0164544.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Unfolded protein response in hypothalamic cultures of wild-type and ATF6α-knockout mice

Lu, W., Hagiwara, D., Morishita, Y., Tochiya, M., Azuma, Y., Suga, H., Goto, M., Banno, R., Sugimura, Y., Oyadomari, S., Mori, K. & Arima, H., 26-01-2016, In : Neuroscience Letters. 612, p. 199-203 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2015

BMP4 and FGF strongly induce differentiation of mouse ES cells into oral ectoderm

Ochiai, H., Suga, H., Yamada, T., Sakakibara, M., Kasai, T., Ozone, C., Ogawa, K., Goto, M., Banno, R., Tsunekawa, S., Sugimura, Y., Arima, H. & Oiso, Y., 01-09-2015, In : Stem Cell Research. 15, 2, p. 290-298 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency

Kiyota, A., Iwama, S., Sugimura, Y., Takeuchi, S., Takagi, H., Iwata, N., Nakashima, K., Suzuki, H., Nishioka, T., Kato, T., Enomoto, A., Arima, H., Kaibuchi, K. & Oiso, Y., 01-01-2015, In : endocrine journal. 62, 2, p. 153-160 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity

Ishikawa, K., Tsunekawa, S., Ikeniwa, M., Izumoto, T., Iida, A., Ogata, H., Uenishi, E., Seino, Y., Ozaki, N., Sugimura, Y., Hamada, Y., Kuroda, A., Shinjo, K., Kondo, Y. & Oiso, Y., 06-02-2015, In : PloS one. 10, 2, e0115350.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Rabphilin-3A as a targeted autoantigen in lymphocytic infundibulo-neurohypophysitis

Iwama, S., Sugimura, Y., Kiyota, A., Kato, T., Enomoto, A., Suzuki, H., Iwata, N., Takeuchi, S., Nakashima, K., Takagi, H., Izumida, H., Ochiai, H., Fujisawa, H., Suga, H., Arima, H., Shimoyama, Y., Takahashi, M., Nishioka, H., Ishikawa, S. E., Shimatsu, A. & 2 others, Caturegli, P. & Oiso, Y., 01-07-2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 7, p. E946-E954

Research output: Contribution to journalArticle

28 Citations (Scopus)
2014

Activating transcription factor 6α is required for the vasopressin neuron system to maintain water balance under dehydration in male mice

Azuma, Y., Hagiwara, D., Lu, W., Morishita, Y., Suga, H., Goto, M., Banno, R., Sugimura, Y., Oyadomari, S., Mori, K., Shiota, A., Asai, N., Takahashi, M., Oiso, Y. & Arima, H., 01-12-2014, In : Endocrinology. 155, 12, p. 4905-4914 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Arginine vasopressin neuronal loss results from autophagy-associated cell death in a mouse model for familial neurohypophysial diabetes insipidus

Hagiwara, D., Arima, H., Morishita, Y., Wenjun, L., Azuma, Y., Ito, Y., Suga, H., Goto, M., Banno, R., Sugimura, Y., Shiota, A., Asai, N., Takahashi, M. & Oiso, Y., 03-2014, In : Cell Death and Disease. 5, 3, e1148.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Minocycline prevents osmotic demyelination associated with aquaresis

Takagi, H., Sugimura, Y., Suzuki, H., Iwama, S., Izumida, H., Fujisawa, H., Ogawa, K., Nakashima, K., Ochiai, H., Takeuchi, S., Kiyota, A., Suga, H., Goto, M., Banno, R., Arima, H. & Oiso, Y., 05-11-2014, In : Kidney International. 86, 5, p. 954-964 11 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Mitogen-activated protein kinase phosphatase 1 negatively regulates MAPK signaling in mouse hypothalamus

Adachi, K., Goto, M., Onoue, T., Tsunekawa, T., Shibata, M., Hagimoto, S., Ito, Y., Banno, R., Suga, H., Sugimura, Y., Oiso, Y. & Arima, H., 21-05-2014, In : Neuroscience Letters. 569, p. 49-54 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2013

A 68-year-old phenotypically male patient with 21-hydroxylase deficiency and concomitant adrenocortical neoplasm producing testosterone and cortisol

Hayashi, M., Kataoka, Y., Sugimura, Y., Kato, F., Fukami, M., Ogata, T., Homma, K., Hasegawa, T., Oiso, Y., Sasano, H. & Tanaka, H., 07-10-2013, In : Tohoku Journal of Experimental Medicine. 231, 2, p. 75-84 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Expression of neuropeptide Y and agouti-related protein mRNA stimulated by glucocorticoids is attenuated via NF-κB p65 under ER stress in mouse hypothalamic cultures

Hagimoto, S., Arima, H., Adachi, K., Ito, Y., Suga, H., Sugimura, Y., Goto, M., Banno, R. & Oiso, Y., 11-10-2013, In : Neuroscience Letters. 553, p. 165-169 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

GABA type B receptor signaling in proopiomelanocortin neurons protects against obesity, insulin resistance, and hypothalamic inflammation in male mice on a high-fat diet

Ito, Y., Banno, R., Shibata, M., Adachi, K., Hagimoto, S., Hagiwara, D., Ozawa, Y., Goto, M., Suga, H., Sugimura, Y., Bettler, B., Oiso, Y. & Arima, H., 2013, In : Journal of Neuroscience. 33, 43, p. 17166-17173 8 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2012

BiP mRNA expression is upregulated by dehydration in vasopressin neurons in the hypothalamus in mice

Hagiwara, D., Arima, H., Morishita, Y., Goto, M., Banno, R., Sugimura, Y. & Oiso, Y., 01-02-2012, In : Peptides. 33, 2, p. 346-350 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Inflammatory changes in adipose tissue enhance expression of GPR84, a medium-chain fatty acid receptor: TNFα enhances GPR84 expression in adipocytes

Nagasaki, H., Kondo, T., Fuchigami, M., Hashimoto, H., Sugimura, Y., Ozaki, N., Arima, H., Ota, A., Oiso, Y. & Hamada, Y., 17-02-2012, In : FEBS Letters. 586, 4, p. 368-372 5 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Lesion of area postrema attenuated hyperphagic responses to glucoprivation, but not transcriptional activation of the neuropeptide y gene in rats

Ozawa, Y., Arima, H., Banno, R., Ito, Y., Goto, M., Morishita, Y., Sugimura, Y., Ozaki, N., Nagasaki, H. & Oiso, Y., 01-08-2012, In : NeuroReport. 23, 11, p. 673-675 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Reduction of insulin signaling upregulates angiopoietin-like protein 4 through elevated free fatty acids in diabetic mice

Mizutani, N., Ozaki, N., Seino, Y., Fukami, A., Sakamoto, E., Fukuyama, T., Sugimura, Y., Nagasaki, H., Arima, H. & Oiso, Y., 01-01-2012, In : Experimental and Clinical Endocrinology and Diabetes. 120, 3, p. 139-144 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2011

Osteoclast response to low extracellular sodium and the mechanism of hyponatremia-induced bone loss

Barsony, J., Sugimura, Y. & Verbalis, J. G., 25-03-2011, In : Journal of Biological Chemistry. 286, 12, p. 10864-10875 12 p.

Research output: Contribution to journalArticle

108 Citations (Scopus)

Poly(A) tail length of neurohypophysial hormones is shortened under endoplasmic reticulum stress

Morishita, Y., Arima, H., Hiroi, M., Hayashi, M., Hagiwara, D., Asai, N., Ozaki, N., Sugimura, Y., Nagasaki, H., Shiota, A., Takahashi, M. & Oiso, Y., 01-12-2011, In : Endocrinology. 152, 12, p. 4846-4855 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Repeated glucoprivation delayed hyperphagic responses while activating neuropeptide Y neurons in rats

Ozawa, Y., Arima, H., Watanabe, M., Shimizu, H., Ito, Y., Banno, R., Sugimura, Y., Ozaki, N., Nagasaki, H. & Oiso, Y., 01-04-2011, In : Peptides. 32, 4, p. 763-769 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Time-dependent changes in proinflammatory and neurotrophic responses of microglia and astrocytes in a rat model of osmotic demyelination syndrome

Iwama, S., Sugimura, Y., Suzuki, H., Suzuki, H., Murase, T., Ozaki, N., Nagasaki, H., Arima, H., Murata, Y., Sawada, M. & Oiso, Y., 01-03-2011, In : GLIA. 59, 3, p. 452-462 11 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2010

Activation of vasopressin neurons leads to phenotype progression in a mouse model for familial neurohypophysial diabetes insipidus

Hiroi, M., Morishita, Y., Hayashi, M., Ozaki, N., Sugimura, Y., Nagasaki, H., Shiota, A., Oiso, Y. & Arima, H., 01-02-2010, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 298, 2, p. R486-R493

Research output: Contribution to journalArticle

16 Citations (Scopus)

Glucocorticoids increase NPY gene expression in the arcuate nucleus by inhibiting mTOR signaling in rat hypothalamic organotypic cultures

Shimizu, H., Arima, H., Ozawa, Y., Watanabe, M., Banno, R., Sugimura, Y., Ozaki, N., Nagasaki, H. & Oiso, Y., 01-01-2010, In : Peptides. 31, 1, p. 145-149 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Hyponatremia-induced osteoporosis

Verbalis, J. G., Barsony, J., Sugimura, Y., Tian, Y., Adams, D. J., Carter, E. A. & Resnick, H. E., 03-2010, In : Journal of Bone and Mineral Research. 25, 3, p. 554-563 10 p.

Research output: Contribution to journalArticle

266 Citations (Scopus)

Minocycline prevents osmotic demyelination syndrome by inhibiting the activation of microglia

Suzuki, H., Sugimura, Y., Iwama, S., Suzuki, H., Nobuaki, O., Nagasaki, H., Arima, H., Sawada, M. & Oiso, Y., 01-12-2010, In : Journal of the American Society of Nephrology. 21, 12, p. 2090-2098 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2009

Central adiponectin functions to inhibit arginine vasopressin release in conscious rats

Iwama, S., Sugimura, Y., Murase, T., Hiroi, M., Goto, M., Hayashi, M., Arima, H. & Oiso, Y., 31-08-2009, In : Journal of Neuroendocrinology. 21, 9, p. 753-759 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Folic acid prevents congenital malformations in the offspring of diabetic mice

Oyama, K., Sugimura, Y., Murase, T., Uchida, A., Hayasaka, S., Oiso, Y. & Murata, Y., 24-03-2009, In : endocrine journal. 56, 1, p. 29-37 9 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Prevention of neural tube defects by loss of function of inducible nitric oxide synthase in fetuses of a mouse model of streptozotocin-induced diabetes

Sugimura, Y., Murase, T., Oyama, K., Uchida, A., Sato, N., Hayasaka, S., Kano, Y., Takagishi, Y., Hayashi, Y., Oiso, Y. & Murata, Y., 01-05-2009, In : Diabetologia. 52, 5, p. 962-971 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

The medial hypothalamus is required for the feeding response to glucoprivation but not to food deprivation

Watanabe, M., Arima, H., Ozawa, Y., Goto, M., Shimizu, H., Banno, R., Sugimura, Y., Ozaki, N., Nagasaki, H. & Oiso, Y., 16-10-2009, In : Neuroscience Letters. 464, 1, p. 6-9 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

α-lipoic acid reduces congenital malformations in the offspring of diabetic mice

Sugimura, Y., Murase, T., Kobayashi, K., Oyama, K., Hayasaka, S., Kanou, Y., Oiso, Y. & Murata, Y., 04-06-2009, In : Diabetes/Metabolism Research and Reviews. 25, 3, p. 287-294 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2008

Differential kinetics of oxytocin and vasopressin heteronuclear RNA expression in the rat supraoptic nucleus in response to chronic salt loading in vivo

Yue, C., Mutsuga, N., Sugimura, Y., Verbalis, J. & Gainer, H., 01-02-2008, In : Journal of Neuroendocrinology. 20, 2, p. 227-232 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Identification of genes differentially expressed in mouse fetuses from streptozotocin-induced diabetic pregnancy by cDNA subtraction

Sato, N., Sugimura, Y., Hayashi, Y., Murase, T., Kanou, Y., Kikkawa, F. & Murata, Y., 19-05-2008, In : endocrine journal. 55, 2, p. 317-323 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2007

Role of microglia in the pathogenesis of osmotic-induced demyelination

Takefuji, S., Murase, T., Sugimura, Y., Takagishi, Y., Hayasaka, S., Oiso, Y. & Murata, Y., 01-03-2007, In : Experimental Neurology. 204, 1, p. 88-94 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2006

Increased renal α-ENaC and NCC abundance and elevated blood pressure are independent of hyperaldosteronism in vasopressin escape

Tiwari, S., Packer, R. K., Hu, X., Sugimura, Y., Verbalis, J. G. & Ecelbarger, C. A., 30-06-2006, In : American Journal of Physiology - Renal Physiology. 291, 1, p. F49-F57

Research output: Contribution to journalArticle

17 Citations (Scopus)

Mechanisms and Therapy of Osmotic Demyelination

Murase, T., Sugimura, Y., Takefuji, S., Oiso, Y. & Murata, Y., 01-07-2006, In : American Journal of Medicine. 119, 7 SUPPL. 1, p. S69-S73

Research output: Contribution to journalArticle

44 Citations (Scopus)