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• 2012

  Living with a nonsmoking partner and smoking cessation of middle-aged Japanese male smokers: A prospective cohort study

  Ota, A., Masue, T., Yasuda, N., Tsutsumi, A., Mino, Y., Ohara, H. & Ono, Y., 01-10-2012, In: Asian Biomedicine. 6, 5, p. 653-658 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Regression analysis
  • Smoking Cessation
  • Tobacco Products
  • Logistics
  • Smokers
  3 Citations (Scopus)

• LMP-420, a Small Molecular Inhibitor of TNF-α, Prolongs Islet Allograft Survival by Induction of Suppressor of Cytokine Signaling-1: Synergistic Effect with Cyclosporin-A

  Angaswamy, N., Fukami, N., Tiriveedhi, V., Cianciolo, G. J. & Mohanakumar, T., 2012, In: Cell Transplantation. 21, 6, p. 1285-1296 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 2-amino-6-chloro-9-((5-dihydroxyboryl)pentyl)purine
  • Cytokines
  • Cyclosporine
  • Allografts
  • Superoxide Dismutase
  7 Citations (Scopus)

• Lobular endocervical glandular hyperplasia and peritoneal pigmentation associated with Peutz-Jeghers syndrome due to a germline mutation of STK11

  Hirasawa, A., Akahane, T., Tsuruta, T., Kobayashi, Y., Masuda, K., Banno, K., Fujii, T., Susumu, N., Itsubo, T., Kameyama, K., Sugano, K. & Aoki, D., 11-2012, In: Annals of Oncology. 23, 11, p. 2990-2992 3 p., mds492.

  Research output: Contribution to journal › Letter › peer-review
  17 Citations (Scopus)

• Longitudinal changes of outcome measures in spinal and bulbar muscular atrophy

  Hashizume, A., Katsuno, M., Banno, H., Suzuki, K., Suga, N., Mano, T., Atsuta, N., Oe, H., Watanabe, H., Tanaka, F. & Sobue, G., 09-2012, In: Brain. 135, 9, p. 2838-2848 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • X-Linked Bulbo-Spinal Atrophy
  • Disease Progression
  • Outcome Assessment (Health Care)
  • Androgen Receptors
  • Age of Onset
  45 Citations (Scopus)

• Long-lived dichotomous lineages of the proteasome subunit beta type 8 (PSMB8) gene surviving more than 500 million years as alleles or paralogs

  Tsukamoto, K., Miura, F., Fujito, N. T., Yoshizaki, G. & Nonaka, M., 10-2012, In: Molecular biology and evolution. 29, 10, p. 3071-3079 9 p.

  Research output: Contribution to journal › Article › peer-review

  • proteasome endopeptidase complex
  • allele
  • Proteasome Endopeptidase Complex
  • gene
  • Alleles
  14 Citations (Scopus)

• Long-term (>10 Years) clinical outcomes of first-in-human biodegradable poly-l-lactic acid coronary stents: Igaki-Tamai stents

  Nishio, S., Kosuga, K., Igaki, K., Okada, M., Kyo, E., Tsuji, T., Takeuchi, E., Inuzuka, Y., Takeda, S., Hata, T., Takeuchi, Y., Kawada, Y., Harita, T., Seki, J., Akamatsu, S., Hasegawa, S., Bruining, N., Brugaletta, S., De Winter, S., Muramatsu, T. & 3 others, Onuma, Y., Serruys, P. W. & Ikeguchi, S., 15-05-2012, In: Circulation. 125, 19, p. 2343-2352 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • poly(lactide)
  • Stents
  • Thrombosis
  • Cause of Death
  • Myocardial Infarction
  178 Citations (Scopus)

• Long-term clinical outcome of patients with recurrent epithelial ovarian carcinoma: Is it the same for each histological type?

  Kajiyama, H., Shibata, K., Mizuno, M., Umezu, T., Suzuki, S., Yamamoto, E., Fujiwara, S., Kawai, M., Nagasaka, T. & Kikkawa, F., 03-2012, In: International Journal of Gynecological Cancer. 22, 3, p. 394-399 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Ovarian Epithelial Carcinoma
  • Survival
  • Carcinoma
  • Histology
  • Multivariate Analysis
  17 Citations (Scopus)

• Long-term size follow-up of knitted Dacron grafts (Gelseal™) used in the ascending aorta

  Takami, Y., Tajima, K., Kato, W., Fujii, K., Hibino, M., Munakata, H., Uchida, K. & Sakai, Y., 05-2012, In: Interactive Cardiovascular and Thoracic Surgery. 14, 5, p. 529-531 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Polyethylene Terephthalates
  • Aorta
  • Transplants
  • Dilatation
  • Tomography
  11 Citations (Scopus)

• Long-term surgical outcomes of spinal meningiomas

  Nakamura, M., Tsuji, O., Fujiyoshi, K., Hosogane, N., Watanabe, K., Tsuji, T., Ishii, K., Toyama, Y., Chiba, K. & Matsumoto, M., 01-05-2012, In: Spine. 37, 10

  Research output: Contribution to journal › Article › peer-review

  • Meningioma
  • Recurrence
  • Neoplasms
  • Dura Mater
  • Reoperation
  69 Citations (Scopus)

• Loss of apical vertebral derotation in adolescent idiopathic scoliosis: 2-year follow-up using multi-planar reconstruction computed tomography

  Cui, G., Watanabe, K., Nishiwaki, Y., Hosogane, N., Tsuji, T., Ishii, K., Nakamura, M., Toyama, Y., Chiba, K. & Matsumoto, M., 06-2012, In: European Spine Journal. 21, 6, p. 1111-1120 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Scoliosis
  • Tomography
  • Pedicle Screws
  • Spine
  • Kyphosis
  18 Citations (Scopus)

• Loss of p16 expression is associated with the stem cell characteristics of surface markers and therapeutic resistance in estrogen receptor-negative breast cancer

  Arima, Y., Hayashi, N., Hayashi, H., Sasaki, M., Kai, K., Sugihara, E., Abe, E., Yoshida, A., Mikami, S., Nakamura, S. & Saya, H., 01-06-2012, In: International Journal of Cancer. 130, 11, p. 2568-2579 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Stem Cells
  • Breast Neoplasms
  • Cell Line
  • Cyclin-Dependent Kinase Inhibitor p16
  54 Citations (Scopus)

• Low susceptibility of NC/Nga mice to the lipopolysaccharide-mediated lethality with D-galactosamine sensitization and the involvement of fewer natural killer T cells

  Koide, N., Morikawa, A., Odkhuu, E., Haque, A., Badamtseren, B., Naiki, Y., Komatsu, T., Yoshida, T. & Yokochi, T., 02-2012, In: Innate Immunity. 18, 1, p. 35-43 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Galactosamine
  • Natural Killer T-Cells
  • Lipopolysaccharides
  • Nitric Oxide
  • Galactosylceramides
  3 Citations (Scopus)

• L-tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice

  Hoshi, M., Matsumoto, K., Ito, H., Ohtaki, H., Arioka, Y., Osawa, Y., Yamamoto, Y., Matsunami, H., Hara, A., Seishima, M. & Saito, K., 15-04-2012, In: Journal of Immunology. 188, 8, p. 3980-3987 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Kynurenine
  • Myocarditis
  • Tryptophan
  • Encephalomyocarditis virus
  • Virus Diseases
  27 Citations (Scopus)

• Lung Image Quality with 320-row Wide-volume CT Scans: The Effect of Prospective ECG-gating and Comparisons with 64-row Helical CT Scans

  Yamashiro, T., Miyara, T., Takahashi, M., Kikuyama, A., Kamiya, H., Koyama, H., Ohno, Y., Moriya, H., Matsuki, M., Tanaka, Y., Noma, S. & Murayama, S., 04-2012, In: Academic Radiology. 19, 4, p. 380-388 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Spiral Computed Tomography
  • Cone-Beam Computed Tomography
  • Electrocardiography
  • Lung
  • Research Ethics Committees
  13 Citations (Scopus)

• Lyn signaling to upregulate GANP is critical for the survival of high-affinity B cells in germinal centers of lymphoid organs

  Kuwahara, K., Nakaya, T., Phimsen, S., Toda, T., Kitabatake, M., Kaji, T., Takemori, T., Watanabe, T. & Sakaguchi, N., 01-10-2012, In: Journal of Immunology. 189, 7, p. 3472-3479 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Germinal Center
  • B-Lymphocytes
  • Up-Regulation
  • Mutation
  • Immunization
  5 Citations (Scopus)

• M ₄muscarinic receptor knockout mice display abnormal social behavior and decreased prepulse inhibition

  Koshimizu, H., Leiter, L. M. & Miyakawa, T., 2012, In: Molecular brain. 5, 1, 10.

  Research output: Contribution to journal › Article › peer-review

  • Prepulse Inhibition
  • Social Behavior
  • Knockout Mice
  • Locomotion
  • Sensory Gating
  29 Citations (Scopus)

• MAGE-D1 regulates expression of depression-like behavior through serotonin transporter ubiquitylation

  Mouri, A., Sasaki, A., Watanabe, K., Sogawa, C., Kitayama, S., Mamiya, T., Miyamoto, Y., Yamada, K., Noda, Y. & Nabeshima, T., 28-03-2012, In: Journal of Neuroscience. 32, 13, p. 4562-4580 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Melanoma-Specific Antigens
  • Serotonin Plasma Membrane Transport Proteins
  • Ubiquitination
  • Depression
  • Proteasome Endopeptidase Complex
  47 Citations (Scopus)

• Magnetic resonance imaging (MRI) of articular cartilage of the knee using ultrashort echo time (uTE) sequences with spiral acquisition

  Goto, H., Fujii, M., Iwama, Y., Aoyama, N., Ohno, Y. & Sugimura, K., 06-2012, In: Journal of Medical Imaging and Radiation Oncology. 56, 3, p. 318-323 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Articular Cartilage
  • Knee
  • Magnetic Resonance Imaging
  • Cartilage
  • Tomography
  9 Citations (Scopus)

• Malassezia globosa tends to grow actively in summer conditions more than other cutaneous Malassezia species

  Akaza, N., Akamatsu, H., Takeoka, S., Sasaki, Y., Mizutani, H., Nakata, S. & Matsunaga, K., 01-07-2012, In: Journal of Dermatology. 39, 7, p. 613-616 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Malassezia
  • Skin
  • Folliculitis
  • Sweat
  • Lipase
  17 Citations (Scopus)

• Malignant transformation of branch duct-type intraductal papillary mucinous neoplasms of the pancreas based on contrast-enhanced endoscopic ultrasonography morphological changes: Focus on malignant transformation of intraductal papillary mucinous neoplasm itself

  Ohno, E., Itoh, A., Kawashima, H., Ishikawa, T., Matsubara, H., Itoh, Y., Nakamura, Y., Hiramatsu, T., Nakamura, M., Miyahara, R., Ohmiya, N., Ishigami, M., Katano, Y., Goto, H. & Hirooka, Y., 08-2012, In: Pancreas. 41, 6, p. 855-862 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Intraductal Neoplasms
  • Endosonography
  • Pancreatic Ducts
  • Neoplasms
  • Multivariate Analysis
  71 Citations (Scopus)

• Marked discrepancy in pressure gradient between Doppler and catheter examinations on Medtronic Mosaic valve in aortic position

  Ito, T., Maekawa, A., Fujii, G., Sawaki, S., Hoshino, S. & Hayashi, Y., 01-12-2012, In: General Thoracic and Cardiovascular Surgery. 60, 12, p. 818-821 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Aortic Valve
  • Catheters
  • Pressure
  • Prosthesis Failure
  • Systole
  3 Citations (Scopus)

• Mast cells promote the growth of Hodgkin's lymphoma cell tumor by modifying the tumor microenvironment that can be perturbed by bortezomib

  Mizuno, H., Nakayama, T., Miyata, Y., Saito, S., Nishiwaki, S., Nakao, N., Takeshita, K. & Naoe, T., 10-2012, In: Leukemia. 26, 10, p. 2269-2276 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bortezomib
  • Tumor Microenvironment
  • Hodgkin Disease
  • Mast Cells
  • Growth

• Matrix metalloproteinase-9 gene polymorphisms and chronic kidney disease

  Okada, R., Kawai, S., Naito, M., Hishida, A., Hamajima, N., Shinchi, K., Chowdhury Turin, T., Suzuki, S., Mantjoro, E. M., Toyomura, K., Arisawa, K., Kuriyama, N., Hosono, S., Mikami, H., Kubo, M., Tanaka, H. & Wakai, K., 11-2012, In: American Journal of Nephrology. 36, 5, p. 444-450 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Matrix Metalloproteinase 9
  • Chronic Renal Insufficiency
  • Matrix Metalloproteinases
  • Tissue Inhibitor of Metalloproteinases
  • Odds Ratio
  13 Citations (Scopus)

• Measurement of operating force and determination of training index for acupuncture training system

  Kanehira, R., Yang, W. & Fujimoto, H., 01-01-2012, p. 468-475. 8 p.

  Research output: Contribution to conference › Paper › peer-review

  • Acupuncture
  • acupuncture
  • Chemical analysis
  • quantification
  • trainee

• Measurement of re ectivity of X-ray mirror for soft x-ray telescope onboard ASTRO-H

  Sugita, S., Furuzawa, A., Ishibashi, K., Tamura, K., Okajima, T., Maeda, Y., Sato, T., Ichihara, K., Tomikawa, K., Iizuka, R., Awaya, T. & Okada, K., 2012, Space Telescopes and Instrumentation 2012: Ultraviolet to Gamma Ray. 844358. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 8443).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Soft X-ray
  • x ray telescopes
  • Reflectivity
  • Telescope
  • Telescopes
  1 Citation (Scopus)

• Measurement of TFF3 mRNA in aspirates from thyroid nodules using mesh filtration: The first clinical trial in 130 cases

  Yamada, H., Takano, T., Kihara, M., Hirokawa, M., Yoshida, H., Watanabe, M., Iwatani, Y., Hidaka, Y. & Miyauchi, A., 2012, In: endocrine journal. 59, 7, p. 621-630 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Trefoil Factor-3
  • Thyroid Nodule
  • Thyroid Gland
  • Clinical Trials
  • Cell Biology
  2 Citations (Scopus)

• Mechanism of accommodation in a sensitized human leukocyte antigen transgenic murine cardiac transplant model

  Fukami, N., Ramachandran, S., Narayanan, K., Liu, W., Nath, D. S., Jendrisak, M., Chapman, W. & Mohanakumar, T., 27-02-2012, In: Transplantation. 93, 4, p. 364-372 9 p.

  Research output: Contribution to journal › Article › peer-review

  • HLA Antigens
  • Heart
  • Transplants
  • Allografts
  • Heme Oxygenase-1
  13 Citations (Scopus)

• Mechanism of complex gross chromosomal rearrangements: A commentary on Concomitant microduplications of MECP2 and ATRX in male patients with severe mental retardation

  Kurahashi, H., Ohye, T., Inagaki, H., Kogo, H. & Tsutsumi, M., 02-2012, In: Journal of Human Genetics. 57, 2, p. 81-83 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  1 Citation (Scopus)

• Mechanistic insights into human pre-mRNA splicing of human ultra-short introns: Potential unusual mechanism identifies G-rich introns

  Sasaki-Haraguchi, N., Shimada, M. K., Taniguchi, I., Ohno, M. & Mayeda, A., 29-06-2012, In: Biochemical and Biophysical Research Communications. 423, 2, p. 289-294 6 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Precursors
  • Introns
  • Genes
  • pyrimidine
  • spliceostatin A
  11 Citations (Scopus)

• Melatonin improves metabolic syndrome induced by high fructose intake in rats

  Kitagawa, A., Ohta, Y. & Ohashi, K., 05-2012, In: Journal of Pineal Research. 52, 4, p. 403-413 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Fructose
  • Melatonin
  • Metabolic Syndrome
  • Serum
  • Insulin Resistance
  83 Citations (Scopus)

• Membrane complement regulators protect against fibrin exudation increases in a severe peritoneal inflammation model in rats

  Mizuno, M., Ito, Y., Mizuno, T., Harris, C. L., Suzuki, Y., Okada, N., Matsuo, S. & Paul Morgan, B., 2012, In: American Journal of Physiology - Renal Physiology. 302, 10, p. F1245-F1251

  Research output: Contribution to journal › Article › peer-review

  • Peritoneal Fibrosis
  • Fibrin
  • Peritoneum
  • Inflammation
  • Membranes
  16 Citations (Scopus)

• Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: Selective serotonin reuptake inhibitor response pharmacogenomics

  Abo, R., Hebbring, S., Ji, Y., Zhu, H., Zeng, Z. B., Batzler, A., Jenkins, G. D., Biernacka, J., Snyder, K., Drews, M., Fiehn, O., Fridley, B., Schaid, D., Kamatani, N., Nakamura, Y., Kubo, M., Mushiroda, T., Kaddurah-Daouk, R., Mrazek, D. A. & Weinshilboum, R. M., 04-2012, In: Pharmacogenetics and genomics. 22, 4, p. 247-253 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacogenetics
  • Serotonin Uptake Inhibitors
  • Single Nucleotide Polymorphism
  • Genome
  • Pharmacogenomic Testing
  46 Citations (Scopus)

• Mesothelin expression correlates with prolonged patient survival in gastric cancer

  Baba, K., Ishigami, S., Arigami, T., Uenosono, Y., Okumura, H., Matsumoto, M., Kurahara, H., Uchikado, Y., Kita, Y., Kijima, Y., Kitazono, M., Shinchi, H., Ueno, S. & Natsugoe, S., 02-2012, In: Journal of Surgical Oncology. 105, 2, p. 195-199 5 p.

  Research output: Contribution to journal › Article › peer-review

  • mesothelin
  • Stomach Neoplasms
  • Survival
  39 Citations (Scopus)

• Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility

  Li, M., Wang, Y., Zheng, X. B., Ikeda, M., Iwata, N., Luo, X. J., Chong, S. A., Lee, J., Rietschel, M., Zhang, F., Müller-Myhsok, B., Cichon, S., Weinberger, D. R., Mattheisen, M., Schulze, T. G., Martin, N. G., Mitchell, P. B., Schofield, P. R., Liu, J. J. & Su, B., 12-2012, In: Schizophrenia Research. 142, 1-3, p. 200-205 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroimaging
  • Schizophrenia
  • Meta-Analysis
  • Genome-Wide Association Study
  • Brain
  39 Citations (Scopus)

• Meta-analysis identifies common variants associated with body mass index in east Asians

  Wen, W., Cho, Y. S., Zheng, W., Dorajoo, R., Kato, N., Qi, L., Chen, C. H., Delahanty, R. J., Okada, Y., Tabara, Y., Gu, D., Zhu, D., Haiman, C. A., Mo, Z., Gao, Y. T., Saw, S. M., Go, M. J., Takeuchi, F., Chang, L. C., Kokubo, Y. & 43 others, Liang, J., Hao, M., Le Marchand, L., Zhang, Y., Hu, Y., Wong, T. Y., Long, J., Han, B. G., Kubo, M., Yamamoto, K., Su, M. H., Miki, T., Henderson, B. E., Song, H., Tan, A., He, J., Ng, D. P. K., Cai, Q., Tsunoda, T., Tsai, F. J., Iwai, N., Chen, G. K., Shi, J., Xu, J., Sim, X., Xiang, Y. B., Maeda, S., Ong, R. T. H., Li, C., Nakamura, Y., Aung, T., Kamatani, N., Liu, J. J., Lu, W., Yokota, M., Seielstad, M., Fann, C. S. J., Wu, J. Y., Lee, J. Y., Hu, F. B., Tanaka, T., Tai, E. S. & Shu, X. O., 03-2012, In: Nature Genetics. 44, 3, p. 307-311 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Meta-Analysis
  • Body Mass Index
  • Obesity
  • Genome
  • Genetic Loci
  254 Citations (Scopus)

• Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

  Okada, Y., Sim, X., Go, M. J., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Seielstad, M., Teo, Y. Y., Kim, Y. J., Lee, J. Y., Han, B. G. & 474 others, Kang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J., Mei, H., Rao, D. C., Hixson, J. E., Chen, S., Katsuya, T., Isono, M., Ogihara, T., Chambers, J. C., Zhang, W., Kooner, J. S., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y. T., Cho, Y. S., Tai, E. S., Tanaka, T., Chambers, J. C., Zhang, W., Lord, G. M., van der Harst, P., Lawlor, D. A., Sehmi, J. S., Gale, D. P., Wass, M. N., Ahmadi, K. R., Bakker, S. J., Beckmann, J., Bilo, H. J., Bochud, M., Brown, M. J., Caulfield, M. J., Connell, J. M., Cook, H. T., Cotlarciuc, I., Smith, G. D., de Silva, R., Deng, G., Devuyst, O., Dikkeschei, L. D., Dimkovic, N., Dockrell, M., Dominiczak, A., Ebrahim, S., Eggermann, T., Farrall, M., Ferrucci, L., Floege, J., Forouhi, N. G., Gansevoort, R. T., Han, X., Hedblad, B., van der Heide, J. J., Hepkema, B. G., Hernandez-Fuentes, M., Hypponen, E., Johnson, T., de Jong, P. E., Kleefstra, N., Lagou, V., Lapsley, M., Li, Y., Loos, R. J., Luan, J., Luttropp, K., Maréchal, C., Melander, O., Munroe, P. B., Nordfors, L., Parsa, A., Peltonen, L., Penninx, B. W., Perucha, E., Pouta, A., Prokopenko, I., Roderick, P. J., Ruokonen, A., Samani, N. J., Sanna, S., Schalling, M., Schlessinger, D., Schlieper, G., Seelen, M. A., Shuldiner, A. R., Sjögren, M., Smit, J. H., Snieder, H., Soranzo, N., Spector, T. D., Stenvinkel, P., Sternberg, M. J., Swaminathan, R., Tanaka, T., Ubink-Veltmaat, L. J., Uda, M., Vollenweider, P., Wallace, C., Waterworth, D., Zerres, K., Waeber, G., Wareham, N. J., Maxwell, P. H., McCarthy, M. I., Jarvelin, M. R., Mooser, V., Abecasis, G. R., Lightstone, L., Scott, J., Navis, G., Elliott, P., Kooner, J. S., Köttgen, A., Pattaro, C., Böger, C. A., Fuchsberger, C., Olden, M., Glazer, N. L., Parsa, A., Gao, X., Yang, Q., Smith, A. V., O'connell, J. R., Li, M., Schmidt, H., Tanaka, T., Isaacs, A., Ketkar, S., Hwang, S. J., Johnson, A. D., Dehghan, A., Teumer, A., Paré, G., Atkinson, E. J., Zeller, T., Lohman, K., Cornelis, M. C., Probst-Hensch, N. M., Kronenberg, F., Tönjes, A., Hayward, C., Aspelund, T., Eiriksdottir, G., Launer, L. J., Harris, T. B., Rampersaud, E., Mitchell, B. D., Arking, D. E., Boerwinkle, E., Struchalin, M., Cavalieri, M., Singleton, A., Giallauria, F., Metter, J., de Boer, I. H., Haritunians, T., Lumley, T., Siscovick, D., Psaty, B. M., Zillikens, M. C., Oostra, B. A., Feitosa, M., Province, M., de Andrade, M., Turner, S. T., Schillert, A., Ziegler, A., Wild, P. S., Schnabel, R. B., Wilde, S., Munzel, T. F., Leak, T. S., Illig, T., Klopp, N., Meisinger, C., Wichmann, H. E., Koenig, W., Zgaga, L., Zemunik, T., Kolcic, I., Minelli, C., Hu, F. B., Johansson, Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Schreiber, S., Aulchenko, Y. S., Felix, J. F., Rivadeneira, F., Uitterlinden, A. G., Hofman, A., Imboden, M., Nitsch, D., Brandstätter, A., Kollerits, B., Kedenko, L., Mägi, R., Stumvoll, M., Kovacs, P., Boban, M., Campbell, S., Endlich, K., Völzke, H., Kroemer, H. K., Nauck, M., Völker, U., Polasek, O., Vitart, V., Badola, S., Parker, A. N., Ridker, P. M., Kardia, S. L., Blankenberg, S., Liu, Y., Curhan, G. C., Franke, A., Rochat, T., Paulweber, B., Prokopenko, I., Wang, W., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., Shlipak, M. G., van Duijn, C. M., Borecki, I., Krämer, B. K., Rudan, I., Gyllensten, U., Wilson, J. F., Witteman, J. C., Pramstaller, P. P., Rettig, R., Hastie, N., Chasman, D. I., Kao, W. H., Heid, I. M., Fox, C. S., Köttgen, A., Albrecht, E., Teumer, A., Vitart, V., Krumsiek, J., Hundertmark, C., Pistis, G., Ruggiero, D., O'seaghdha, M., Haller, T., Yang, Q., Tanaka, T., Johnson, A. D., Kutalik, Z., Smith, A. V., Shi, J., Struchalin, M., Middelberg, P. S., Brown, M. J., Gaffo, A. L., Pirastu, N., Li, G., Hayward, C., Zemunik, T., Huffman, J., Yengo, L., Zhao, J. H., Demirkan, A., Feitosa, M. F., Liu, X., Malerba, G., Lopez, L. M., Li, X., Kleber, M. E., Hicks, A. A., Nolte, I. M., Johansson, A., Murgia, F., Wild, S. H., Bakker, S. J., Peden, J. F., Dehghan, A., Steri, M., Tenesa, A., Lagou, V., Salo, P., Mangino, M., Rose, L. M., Lehtimäki, T., Woodward, O. M., Okada, Y., Tin, A., Müller, C., Oldmeadow, C., Putku, M., Czamara, D., Kraft, P., Frogheri, L., Thun, G. A., Grotevendt, A., Gislason, G. K., Harris, T. B., Launer, L. J., McArdle, P., Shuldiner, A. R., Boerwinkle, E., Schmidt, H., Schallert, M., Martin, N. G., Montgomery, G. W., Kubo, M., Nakamura, Y., Tanaka, T., Samani, N. J., Jacobs, D. R., Liu, K., D'adamo, P., Ulivi, S., Rotter, J. I., Psaty, B. M., Vollenweider, P., Waeber, G., Campbell, S., Devuyst, O., Navaro, P., Kolcic, I., Hastie, N., Balkau, B., Froguel, P., Esko, T., Salumets, A., Khaw, K. T., Langenberg, C., Wareham, N. J., Isaacs, A., Kraja, A., Zhang, Q., Wild, P. S., Scott, R. J., Holliday, E. G., Org, E., Viigimaa, M., Bandinelli, S., Metter, J. E., Lupo, A., Trabetti, E., Sorice, R., Döring, A., Lattka, E., Strauch, K., Theis, F., Waldenberger, M., Wichmann, H. E., Davies, G., Gow, A. J., Bruinenberg, M., Stolk, R. P., Kooner, J. S., Zhang, W., Winkelmann, B. R., Boehm, B. O., Lucae, S., Penninx, B. W., Smit, J. H., Curhan, G., Mudgal, P., Plenge, R. M., Portas, L., Persico, I., Kirin, M., Wilson, J. F., Mateo Leach, I., van Gilst, W. H., Goel, A., Ongen, H., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Imboden, M., von Eckardstein, A., Cucca, F., Nagaraja, R., Piras, M. G., Nauck, M., Schurmann, C., Budde, K., Ernst, F., Farrington, S. M., Theodoratou, E., Prokopenko, I., Stumvoll, M., Jula, A., Perola, M., Salomaa, V., Shin, S. Y., Spector, T. D., Sala, C., Ridker, P. M., Kähönen, M., Viikari, J., Hengstenberg, C., Nelson, C. P., Meschia, J. F., Nalls, M. A., Sharma, P., Singleton, A. B., Kamatani, N., Zeller, T., Burnier, M., Attia, J., Laan, M., Klopp, N., Hillege, H. L., Kloiber, S., Choi, H., Pirastu, M., Tore, S., Probst-Hensch, N. M., Völzke, H., Gudnason, V., Parsa, A., Schmidt, R., Whitfield, J. B., Fornage, M., Gasparini, P., Siscovick, D. S., Polasek, O., Campbell, H., Rudan, I., Bouatia-Naji, N., Metspalu, A., Loos, R. J., van Duijn, C. M., Borecki, I. B., Ferrucci, L., Gambaro, G., Deary, I. J., Wolffenbuttel, B. H., Chambers, J. C., März, W., Pramstaller, P. P., Snieder, H., Gyllensten, U., Wright, A. F., Navis, G., Watkins, H., Witteman, J. C., Sanna, S., Schipf, S., Dunlop, M. G., Tönjes, A., Ripatti, S., Soranzo, N., Toniolo, D., Chasman, D. I., Raitakari, O., Kao, W. H., Ciullo, M., Fox, C. S., Caulfield, M., Bochud, M. & Gieger, C., 01-08-2012, In: Nature Genetics. 44, 8, p. 904-909 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Meta-Analysis
  • Kidney
  • Population
  • Chronic Renal Insufficiency
  • Creatinine
  177 Citations (Scopus)

• Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

  Okada, Y., Terao, C., Ikari, K., Kochi, Y., Ohmura, K., Suzuki, A., Kawaguchi, T., Stahl, E. A., Kurreeman, F. A. S., Nishida, N., Ohmiya, H., Myouzen, K., Takahashi, M., Sawada, T., Nishioka, Y., Yukioka, M., Matsubara, T., Wakitani, S., Teshima, R., Tohma, S. & 31 others, Takasugi, K., Shimada, K., Murasawa, A., Honjo, S., Matsuo, K., Tanaka, H., Tajima, K., Suzuki, T., Iwamoto, T., Kawamura, Y., Tanii, H., Okazaki, Y., Sasaki, T., Gregersen, P. K., Padyukov, L., Worthington, J., Siminovitch, K. A., Lathrop, M., Taniguchi, A., Takahashi, A., Tokunaga, K., Kubo, M., Nakamura, Y., Kamatani, N., Mimori, T., Plenge, R. M., Yamanaka, H., Momohara, S., Yamada, R., Matsuda, F. & Yamamoto, K., 05-2012, In: Nature Genetics. 44, 5, p. 511-516 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Rheumatoid Arthritis
  • Meta-Analysis
  • Population
  • Graves Disease
  • Genome-Wide Association Study
  203 Citations (Scopus)

• Meta-analysis identifies six new susceptibility loci for atrial fibrillation

  Ellinor, P. T., Lunetta, K. L., Albert, C. M., Glazer, N. L., Ritchie, M. D., Smith, A. V., Arking, D. E., Müller-Nurasyid, M., Krijthe, B. P., Lubitz, S. A., Bis, J. C., Chung, M. K., Dörr, M., Ozaki, K., Roberts, J. D., Smith, J. G., Pfeufer, A., Sinner, M. F., Lohman, K., Ding, J. & 69 others, Smith, N. L., Smith, J. D., Rienstra, M., Rice, K. M., Van Wagoner, D. R., Magnani, J. W., Wakili, R., Clauss, S., Rotter, J. I., Steinbeck, G., Launer, L. J., Davies, R. W., Borkovich, M., Harris, T. B., Lin, H., Völker, U., Völzke, H., Milan, D. J., Hofman, A., Boerwinkle, E., Chen, L. Y., Soliman, E. Z., Voight, B. F., Li, G., Chakravarti, A., Kubo, M., Tedrow, U. B., Rose, L. M., Ridker, P. M., Conen, D., Tsunoda, T., Furukawa, T., Sotoodehnia, N., Xu, S., Kamatani, N., Levy, D., Nakamura, Y., Parvez, B., Mahida, S., Furie, K. L., Rosand, J., Muhammad, R., Psaty, B. M., Meitinger, T., Perz, S., Wichmann, H. E., Witteman, J. C. M., Kao, W. H. L., Kathiresan, S., Roden, D. M., Uitterlinden, A. G., Rivadeneira, F., McKnight, B., Sjögren, M., Newman, A. B., Liu, Y., Gollob, M. H., Melander, O., Tanaka, T., Stricker, B. H. C., Felix, S. B., Alonso, A., Darbar, D., Barnard, J., Chasman, D. I., Heckbert, S. R., Benjamin, E. J., Gudnason, V. & Kääb, S., 06-2012, In: Nature Genetics. 44, 6, p. 670-675 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Atrial Fibrillation
  • Meta-Analysis
  • Genome-Wide Association Study
  • Ion Channels
  • Computer Simulation
  404 Citations (Scopus)

• Metabolic profiling reveals new serum biomarkers for differentiating diabetic nephropathy

  Hirayama, A., Nakashima, E., Sugimoto, M., Akiyama, S. I., Sato, W., Maruyama, S., Matsuo, S., Tomita, M., Yuzawa, Y. & Soga, T., 12-2012, In: Analytical and Bioanalytical Chemistry. 404, 10, p. 3101-3109 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolites
  • Biomarkers
  • Diabetic Nephropathies
  • symmetric dimethylarginine
  • azelaic acid
  106 Citations (Scopus)

• Metabolic syndrome and gas messenger

  Yuzawa, Y., 20-02-2012, In: Therapeutic Research. 33, 2, p. 207-208 2 p.

  Research output: Contribution to journal › Article › peer-review

• Metabolism of sesamin by CYPs and UGTs in human liver

  Sakaki, T., Yasuda, K., Kamakura, M., Munetsuna, E., Ohta, M. & Ikushiro, S., 01-04-2012, In: Journal of Food and Drug Analysis. 20, SUPPL.1, p. 376-379 4 p.

  Research output: Contribution to journal › Article › peer-review

  • sesamin
  • catechol
  • metabolism
  • liver
  • Liver
  1 Citation (Scopus)

• Microglial activation in neuroinflammation: Implications for the etiology of neurodegeneration

  Kaneko, Y. S., Nakashima, A., Mori, K., Nagatsu, T., Nagatsu, I. & Ota, A., 01-04-2012, In: Neurodegenerative Diseases. 10, 1-4, p. 100-103 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Microglia
  • Lipopolysaccharides
  • Autophagy
  • Cell Death
  • bcl-2-Associated X Protein
  14 Citations (Scopus)

• Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis

  Hyodo, T., Ito, S., Hasegawa, H., Asano, E., Maeda, M., Urano, T., Takahashi, M., Hamaguchi, M. & Senga, T., 20-07-2012, In: Journal of Biological Chemistry. 287, 30, p. 25019-25029 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cytokinesis
  • Phosphoric Monoester Hydrolases
  • Phosphotransferases
  • Protein Phosphatase 2
  • Phosphoprotein Phosphatases
  35 Citations (Scopus)

• Mizoribine-An inosine monophosphate dehydrogenase inhibitor-acts synergistically with cyclosporine A in prolonging survival of murine islet cell and heart transplants across major histocompatibility barrier

  Fukami, N., Subramanian, V., Angaswamy, N., Liu, W., Mohanakumar, T. & Hoshinaga, K., 03-2012, In: Transplant Immunology. 26, 2-3, p. 140-145 6 p.

  Research output: Contribution to journal › Article › peer-review

  • mizoribine
  • Inosine Monophosphate
  • Histocompatibility
  • Islets of Langerhans
  • Cyclosporine
  1 Citation (Scopus)

• Mobilization and lymph node dissection of the upper stomach

  Isogaki, J., Uyama, I., Kim, H. H. & Park, Y. K., 01-01-2012, Laparoscopic Gastrectomy for Cancer: Standard Techniques and Clinical Evidences. Springer Japan, p. 107-109 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Lymph Node Excision
  • Stomach
  • Splenic Artery
  • Splenectomy
  • Gastrectomy

• Modulation of ammonium perfluorooctanoate-induced hepatic damage by genetically different PPARα in mice

  Nakagawa, T., Ramdhan, D. H., Tanaka, N., Naito, H., Tamada, H., Ito, Y., Li, Y., Hayashi, Y., Yamagishi, N., Yanagiba, Y., Aoyama, T., Gonzalez, F. J. & Nakajima, T., 01-2012, In: Archives of Toxicology. 86, 1, p. 63-74 12 p.

  Research output: Contribution to journal › Article › peer-review

  • perfluorooctanoic acid
  • Peroxisome Proliferator-Activated Receptors
  • Modulation
  • Liver
  • Diacylglycerol O-Acyltransferase
  12 Citations (Scopus)

• Modulation of glucose metabolism by CD44 contributes to antioxidant status and drug resistance in cancer cells

  Tamada, M., Nagano, O., Tateyama, S., Ohmura, M., Yae, T., Ishimoto, T., Sugihara, E., Onishi, N., Yamamoto, T., Yanagawa, H., Suematsu, M. & Saya, H., 15-03-2012, In: Cancer Research. 72, 6, p. 1438-1448 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drug Resistance
  • Antioxidants
  • Glucose
  • Pentose Phosphate Pathway
  • Neoplasms
  142 Citations (Scopus)

• Molecular basis of maternal age-related increase in oocyte aneuploidy

  Kurahashi, H., Tsutsumi, M., Nishiyama, S., Kogo, H., Inagaki, H. & Ohye, T., 03-2012, In: Congenital anomalies. 52, 1, p. 8-15 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Meiosis
  • Maternal Age
  • Aneuploidy
  • Oocytes
  • Down Syndrome
  27 Citations (Scopus)

• Molecular biology of glioma

  Marumoto, T. & Saya, H., 2012, Glioma: Immunotherapeutic Approaches. Yamanaka, R. (ed.). p. 2-11 10 p. (Advances in Experimental Medicine and Biology; vol. 746).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Molecular biology
  • Glioblastoma
  • Glioma
  • MicroRNAs
  • Molecular Biology
  53 Citations (Scopus)

• Molecular biology of the head and neck squamous cell carcinoma

  Ishikawa, S., Tateya, I., Hirano, S. & Ito, J., 01-04-2012, In: Practica Oto-Rhino-Laryngologica. 105, 4, p. 393-402 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Squamous Cell Carcinoma of Head and Neck
  • Molecular Biology
  • Biomarkers
  • Neoplasm Metastasis
  • Papillomaviridae