Find Research Outputs

1991
25 Citations (Scopus)

Memory impairment and morphological changes in rats induced by active fragment of anti-nerve growth factor-antibody

Nabeshima, T., Ogawa, S. I., Ishimaru, H., Kameyama, T., Fukuta, T., Takeuchi, R. & Hayashi, K., 28-02-1991, In : Biochemical and Biophysical Research Communications. 175, 1, p. 215-219 5 p.

Research output: Contribution to journalArticle

Nerve Growth Factor
Rats
Data storage equipment
Antibodies
Rat control
2 Citations (Scopus)

Minor changes in regional cerebral blood flow revealed by the early distribution of I-123 IMP in brain

Takeshita, G., Toyama, H., Nakane, K., Maeda, H., Katada, K., Takeuchi, A. & Koga, S., 01-12-1991, In : Radiation Medicine - Medical Imaging and Radiation Oncology. 9, 5, p. 196-201 6 p.

Research output: Contribution to journalArticle

Iodine Radioisotopes
Cerebrovascular Circulation
amphetamines
Iofetamine
IMP
71 Citations (Scopus)

Monoclonal nature of transient abnormal myelopoiesis in Down's syndrome

Kurahashi, H., Hara, J., Yumura-Yagi, K., Murayama, N., Inoue, M., Ishihara, S., Tawa, A., Okada, S. & Kawa-Ha, K., 01-01-1991, In : Blood. 77, 6, p. 1161-1163 3 p.

Research output: Contribution to journalArticle

Down Syndrome
Methylation
Restriction Fragment Length Polymorphisms
Polymorphism
Multipotent Stem Cells
8 Citations (Scopus)

Naftidrofuryl oxalate, nootropic effects on the scopolamine- and the basal forebrain lesion-induced amnesia in rats

Ogawa, S. I., Kameyama, T. & Nabeshima, T., 01-01-1991, In : Pharmacology, Biochemistry and Behavior. 39, 4, p. 997-1002 6 p.

Research output: Contribution to journalArticle

Nafronyl
Nootropic Agents
Scopolamine Hydrobromide
Amnesia
Oxalates
4 Citations (Scopus)

Neuroprotective and antiamnesic effects of NMDA antagonists

Yamada, K. & Nabeshima, T., 01-12-1991, In : Drug News and Perspectives. 4, 9, p. 524-529 6 p.

Research output: Contribution to journalShort survey

Neuroprotective Agents
N-Methylaspartate
8 Citations (Scopus)

Pharmacokinetic and pharmacodynamic properties of some phencyclidine analogs in rats

Cho, A. K., Masayuki Hiramatsu, H., Schmitz, D. A., Nabeshima, T. & Tsutomu Kameyama, K., 01-01-1991, In : Pharmacology, Biochemistry and Behavior. 39, 4, p. 947-953 7 p.

Research output: Contribution to journalArticle

Pharmacodynamics
Phencyclidine
Pharmacokinetics
Rats
Dizocilpine Maleate
5 Citations (Scopus)

Pharmacokinetic characteristics of N7‐substituted theophylline derivatives and their interaction with quinolone in rats

Hasegawa, T., Nadai, M., Apichartpichean, R., Muraoka, I., Nabeshima, T. & Takagi, K., 01-01-1991, In : Journal of Pharmaceutical Sciences. 80, 10, p. 962-965 4 p.

Research output: Contribution to journalArticle

Quinolones
Dyphylline
Theophylline
Pharmacokinetics
Enoxacin

Prevalence of intractable diseases based on the patient surveys

Minowa, M., Hashimoto, S., Nagai, M., Fujimoto, S. & Fujita, T., 01-03-1991, In : [Nippon koshu eisei zasshi] Japanese journal of public health. 38, 3, p. 219-224 6 p.

Research output: Contribution to journalArticle

Meniere Disease
Thyrotoxicosis
Glomerulonephritis
Health Surveys
Pancreatitis
3 Citations (Scopus)

Properties of the promoter region of the T18d (T13c)Tla gene

Horie, M., Matsuura, A., Chang, K. J., Niikawa, J. & Shen, F. W., 01-05-1991, In : Immunogenetics. 33, 3, p. 171-177 7 p.

Research output: Contribution to journalArticle

Genetic Promoter Regions
Chloramphenicol O-Acetyltransferase
Genes
Thymocytes
T-Cell Leukemia
2 Citations (Scopus)

Quantitative measurement of regional cerebral blood flow with I-123 IMP SPECT: A correction of the microsphere model by global extraction between artery and internal jugular vein

Takeshita, G., Toyama, H., Nakane, K., Maeda, H., Katada, K., Takeuchi, A. & Koga, S., 01-12-1991, In : Annals of Nuclear Medicine. 5, 4, p. 145-148 4 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Iofetamine
Jugular Veins
Regional Blood Flow
Single-Photon Emission-Computed Tomography
75 Citations (Scopus)

Reactivation of herpesvirus type 6 in children receiving bone marrow transplants for leukemia

Asano, Y., Yoshikawa, T., Suga, S., Nakashima, T., Yazaki, T., Fukuda, M., Kojima, S. & Matsuyama, T., 28-02-1991, In : New England Journal of Medicine. 324, 9, p. 634-635 2 p.

Research output: Contribution to journalLetter

Herpesviridae
Blood Cells
Leukemia
Bone Marrow
Human Herpesvirus 6
5 Citations (Scopus)
Recovery of Function
Fingers
Somatosensory Evoked Potentials
Electric Stimulation
Healthy Volunteers
2 Citations (Scopus)

Relation of baseline examination results to death from ischemic heart disease, cerebro-vascular disease and sudden death

Matsumoto, K., Ohta, T., Iwatsuka, T., Hashimoto, S. & Fukutomi, K., 01-01-1991, In : [Nippon kōshū eisei zasshi] Japanese journal of public health. 38, 6, p. 410-416 7 p.

Research output: Contribution to journalArticle

Sudden Death
Vascular Diseases
Myocardial Ischemia
Odds Ratio
Electrocardiography
3 Citations (Scopus)

Remarkable recovery from rejection by treatment with deoxyspergualin and methylprednisolone on canine kidney allografts

Suzuki, S., Hayashi, R., Niiya, S., Kenmochi, T., Fukuoka, T. & Amemiya, H., 01-01-1991, In : Transplantation Proceedings. 23, 1 I, p. 545-546 2 p.

Research output: Contribution to journalArticle

Guanidines
Homologous Transplantation
Methylprednisolone
Graft Rejection
Immunosuppressive Agents
25 Citations (Scopus)

Response Bias in the Nationwide Epidemiological Survey of an Intractable Disease In Japan

Hashimoto, S., Fukutomi, K., Nagal, M., Nakamura, Y., Yanagawa, H., Sasaki, R., Ohno, Y. & Aoki, K., 01-01-1991, In : Journal of Epidemiology. 1, 1, p. 27-30 4 p.

Research output: Contribution to journalArticle

Japan
Purpura
Surveys and Questionnaires
Therapeutics
954 Citations (Scopus)

Sequence and expression of a metabotropic glutamate receptor

Masu, M., Tanabe, Y., Tsuchida, K., Shigemoto, R. & Nakanishi, S., 01-01-1991, In : Nature. 349, 6312, p. 760-765 6 p.

Research output: Contribution to journalArticle

Parahippocampal Gyrus
Metabotropic Glutamate Receptors
Inositol Phosphates
Purkinje Cells
Dentate Gyrus
11 Citations (Scopus)

Sequence‐dependent Termination of Mammalian DNA Polymerase Reaction by a New Platinum Compound, (–)‐(R)‐2‐Aminomethylpyrrolidine(1,1‐cyclobutane‐dicarboxylato)‐2‐platinum(II) Monohydrate

Iwata, M., Izuta, S., Suzuki, M., Kojima, K., Furuhashi, Y., Tomoda, Y. & Yoshida, S., 01-01-1991, In : Japanese Journal of Cancer Research. 82, 4, p. 433-439 7 p.

Research output: Contribution to journalArticle

Platinum Compounds
DNA-Directed DNA Polymerase
DNA Polymerase I
DNA
Pharmaceutical Preparations
3 Citations (Scopus)

Serum lipid and apolipoprotein levels in patients with chronic pancreatitis

Seishima, M., Torizawa, H., Saito, K., Nakamura, T., Murakami, N., Muto, Y., Nakamura, Y. & Noma, A., 01-01-1991, In : Rinsho byori. The Japanese journal of clinical pathology. 39, 11, p. 1191-1194 4 p.

Research output: Contribution to journalArticle

Apolipoproteins
Chronic Pancreatitis
Apolipoprotein A-I
Lipids
Serum
60 Citations (Scopus)

Severity of human herpesvirus-6 viremia and clinical findings in infants with exanthem subitum

Asano, Y., Nakashima, T., Yoshikawa, T., Suga, S. & Yazaki, T., 01-01-1991, In : The Journal of Pediatrics. 118, 6, p. 891-895 5 p.

Research output: Contribution to journalArticle

Human Herpesvirus 6
Viremia
Exanthema
Fever
Viruses
28 Citations (Scopus)

Simultaneous occurrence of human herpesvirus 6 infection and intussusception in three infants

Asano, Y., Yoshikawa, T., Suga, S., Hata, T., Yamazaki, T. & Yazaki, T., 01-01-1991, In : Pediatric Infectious Disease Journal. 10, 4, p. 335-337 3 p.

Research output: Contribution to journalArticle

Human Herpesvirus 6
Herpesviridae Infections
Intussusception
Neutralizing Antibodies
1 Citation (Scopus)

Somatosensory Vertex Potentials: Comparison Between Bilaterally and Unilaterally Evoked Potentials

Okajima, Y., Chino, N., Saitoh, E. & Kimura, A., 01-01-1991, In : the keio journal of medicine. 40, 4, p. 235-239 5 p.

Research output: Contribution to journalArticle

Evoked Potentials
Fingers
Somatosensory Evoked Potentials
Scalp
Healthy Volunteers
7 Citations (Scopus)

Specific binding of L-tryptophan to serum albumin and its function in vivo

Sasaki, E., Saito, K., Ohta, Y., Ishiguro, I., Nagamura, Y., Shinohara, R., Takahashi, H. & Tagaya, O., 19-11-1991, In : Advances in Experimental Medicine and Biology. 294, p. 611-614 4 p.

Research output: Contribution to journalArticle

Mutant Strains Rats
Biological Transport
Inbred Strains Rats
Phenylalanine
Protein Binding
11 Citations (Scopus)

Staurosporine, a protein kinase inhibitor, attenuates basal forebrain-lesion-induced amnesia and cholinergic neuronal deficit

Nabeshima, T., Ogawa, S. I., Nishimura, H., Fuji, K., Kameyama, T. & Sasaki, Y., 14-01-1991, In : Neuroscience Letters. 122, 1, p. 13-16 4 p.

Research output: Contribution to journalArticle

Amnesia
Staurosporine
Protein Kinase Inhibitors
Cholinergic Agents
Parietal Lobe
35 Citations (Scopus)

Staurosporine facilitates recovery from the basal forebrain-lesion-induced impairment of learning and deficit of cholinergic neuron in rats

Nabeshima, T., Ogawa, S. I., Nishimura, H., Fuji, K., Kameyama, T. & Sasaki, Y., 01-01-1991, In : Journal of Pharmacology and Experimental Therapeutics. 257, 2, p. 562-566 5 p.

Research output: Contribution to journalArticle

Cholinergic Neurons
Staurosporine
Learning
Alzheimer Disease
Reversal Learning
14 Citations (Scopus)

Stimulation of DNA Polymerase α Activity by Microtubule-Associated Proteins

Shioda, M., Okuhara, K., Murofushi, H., Mori, A., Sakai, H., Murakami-Murofushi, K., Suzuki, M. & Yoshida, S., 01-12-1991, In : Biochemistry. 30, 48, p. 11403-11412 10 p.

Research output: Contribution to journalArticle

Microtubule-Associated Proteins
DNA-Directed DNA Polymerase
Poly dA-dT
DNA
Deoxyribonucleotides
26 Citations (Scopus)

Strain difference in expression of the adult-type polycystic kidney disease gene, pcy, in the mouse.

Nagao, S., Hibino, T., Koyama, Y., Marunouchi, T., Konishi, H. & Takahashi, H., 01-01-1991, In : Jikken dobutsu. Experimental animals. 40, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

Autosomal Dominant Polycystic Kidney
strain differences
Genes
kidneys
Kidney
19 Citations (Scopus)

Structure‐pharmacokinetic Relationships among the N1, N3‐Alkylxanthines in Rats

Apichartpichean, R., Hasegawa, T., Nadai, M., Kuzuya, T. & Nabeshima, T., 01-01-1991, In : Journal of Pharmacy and Pharmacology. 43, 4, p. 262-269 8 p.

Research output: Contribution to journalArticle

Urine
Xanthine
Protein Binding
Intravenous Administration
Blood Proteins
9 Citations (Scopus)

Structure‐Related Inhibitory Effect of Quinolones on Alky1‐Xanthine Elimination in Rats

Hasegawa, T., Kuzuya, T., Apichartpichean, R., Nadai, M., Nitta, A., Takagi, K. & Nabeshima, T., 01-01-1991, In : Pharmacology & Toxicology. 69, 1, p. 5-8 4 p.

Research output: Contribution to journalArticle

Quinolones
Enoxacin
Theophylline
Rats
Derivatives
1 Citation (Scopus)

Synergistic effect of cyclosporine and mizoribine on canine pancreas allograft survival

Hayashi, R., Kenmochi, T., Fukuoka, T., Suzuki, S. & Amemiya, H., 01-01-1991, In : Transplantation Proceedings. 23, 1 II, p. 1585-1586 2 p.

Research output: Contribution to journalArticle

Cyclosporins
Drug Synergism
Ribonucleosides
Pancreas Transplantation
Graft Survival
2 Citations (Scopus)

Systems analytical investigation of the effect of countermeasures against the AIDS epidemic among homosexuals

Morio, S., Soda, K., Hashimoto, S., Fukutomi, K. & Nakayama, H., 01-01-1991, In : Japanese Journal of Hygiene. 46, 5, p. 966-975 10 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

The 5′-triphosphates of 3′-azido-3′-deoxythymidine and 2′, 3′-dideoxynucleosides inhibit DNA polymerase γ by different mechanisms

Izuta, S., Saneyoshi, M., Sakurai, T., Suzuki, M., Kojima, K. & Yoshida, S., 16-09-1991, In : Biochemical and Biophysical Research Communications. 179, 2, p. 776-783 8 p.

Research output: Contribution to journalArticle

Dideoxynucleosides
Zidovudine
DNA-Directed DNA Polymerase
splenotritin
DNA Primers
21 Citations (Scopus)

The Effect of Tacrine (THA) on Cycloheximide-and Basal Forebrain Lesion-Induced Memory Deficit in Rats

Nabeshima, T., Maruyama, E., Katoh, A. & Kameyama, T., 01-01-1991, In : The Japanese Journal of Pharmacology. 57, 3, p. 311-319 9 p.

Research output: Contribution to journalArticle

Tacrine
Amnesia
Memory Disorders
Cycloheximide
Water
8 Citations (Scopus)

The effects of drinking, smoking and physical constitution on high density lipoprotein cholesterol, apolipoprotein AI and AII levels

Maeda, K., Hashimoto, S., Okamoto, K., Saito, Y., Ohtsuka, T., Ohtsuka, S., Takahashi, A., Okamoto, N., Ohno, K., Hattori, Y., Yagyu, K., Toyoshima, H. & Kato, T., 01-01-1991, In : Japanese Journal of Hygiene. 46, 2, p. 699-708 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

The influence of the time activity variation on dynamic SPECT images in camera based SPECT

Maeda, H., Takeda, K., Matsumura, K., Nakagawa, T., Kitano, T., Ejiri, K., Kondou, T., Takeuchi, A., Toyama, H., Takeshita, G., Koga, S. & Ichihara, T., 01-01-1991, In : Kakuigaku. 28, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Single-Photon Emission-Computed Tomography
Kidney
Gamma Cameras
Information Storage and Retrieval
Radioisotopes
177 Citations (Scopus)

Trophic effect of β-amyloid precursor protein on cerebral cortical neurons in culture

Araki, W., Kitaguchi, N., Tokushima, Y., Ishii, K., Aratake, H., Shimohama, S., Nakamura, S. & Kimura, J., 27-11-1991, In : Biochemical and Biophysical Research Communications. 181, 1, p. 265-271 7 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Neurons
COS Cells
Serum-Free Culture Media
Neurites
3 Citations (Scopus)

Two types of abnormal somatosensory evoked potentials in chronic cerebellar ataxias

Okajima, Y., Chino, N., Saitoh, E., Tsubahara, A., Kimura, A. & Mihara, B., 01-01-1991, In : American Journal of Physical Medicine and Rehabilitation. 70, 2, p. 96-100 5 p.

Research output: Contribution to journalArticle

Cerebellar Ataxia
Somatosensory Evoked Potentials
Olivopontocerebellar Atrophies
Multiple Sclerosis
Central Nervous System
147 Citations (Scopus)

Utility of an elevated plus-maze for dissociation of amnesic and behavioral effects of drugs in mice

Itoh, J., Nabeshima, T. & Kameyama, T., 26-02-1991, In : European Journal of Pharmacology. 194, 1, p. 71-76 6 p.

Research output: Contribution to journalArticle

Scopolamine Hydrobromide
Methamphetamine
Butylscopolammonium Bromide
Pharmaceutical Preparations
Dizocilpine Maleate
1990
16 Citations (Scopus)

[3H]Thienylcyclohexylpiperidine Binding Activity in Brain Synaptic Membranes Treated with Triton X‐100

Ogita, K., Nabeshima, T. & Yoneda, Y., 01-01-1990, In : Journal of Neurochemistry. 55, 5, p. 1639-1646 8 p.

Research output: Contribution to journalArticle

tenocyclidine
Synaptic Membranes
Octoxynol
Glycine
Brain
10 Citations (Scopus)

A monoclonal antibody (8H3) that binds to rat T lineage cells and augments in vitro proliferative responses

Torimoto, Y., Kinebuchi, M., Matsuura, A., Kikuchi, K. & Uede, T., 01-11-1990, In : Journal of Experimental Medicine. 172, 5, p. 1315-1323 9 p.

Research output: Contribution to journalArticle

Thymocytes
Monoclonal Antibodies
Antibodies
Surface Antigens
glycyl-arginyl-glycyl-glutamyl-seryl-proline

Angiographic features of coronary spasm in patients with recurrent vasospastic angina

Ozaki, Y., Takatsu, F., Osugi, J., Anno, T., Kodama, I. & Toyama, J., 01-12-1990, In : Environmental Medicine. 34, p. 145-147 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Application of the indirect hemagglutination test using glutaraldehyde-fixed chicken red blood cells to serological diagnosis of amebiasis

Yamaura, H., Shirasaka, R., Sato, J., Odagiri, Y., Iseki, M., Kimata, I., Maeno, Y., Nakamura, O. & Totani, T., 01-12-1990, In : Japanese Journal of Parasitology. 39, 5, p. 468-474 7 p.

Research output: Contribution to journalArticle

Hemagglutination Tests
Amebiasis
Glutaral
Chickens
Erythrocytes

A study of growth prediction of low-birth-weight infants

Nakabayashi, M., Hashimoto, S., Miura, K., Nakada, K., Hayashi, K. & Yatsushiro, Y., 01-01-1990, In : [Nippon kōshū eisei zasshi] Japanese journal of public health. 37, 11, p. 899-904 6 p.

Research output: Contribution to journalArticle

Low Birth Weight Infant
Weights and Measures
Growth
Birth Weight
Regression Analysis
8 Citations (Scopus)

Attenuation of benzodiazepine-induced passive avoidance deficit by post-training administration of muscimol: interaction with the cholinergic neuronal system

Nabeshima, T., Tohyama, K., Ichihara, K. & Kameyama, T., 17-07-1990, In : European Journal of Pharmacology. 182, 3, p. 555-560 6 p.

Research output: Contribution to journalArticle

Chlordiazepoxide
Muscimol
Benzodiazepines
Cholinergic Agents
GABA-A Receptor Antagonists
44 Citations (Scopus)

Behavioral changes induced by stressful situations: Effects of enkephalins, dynorphin, and their interactions

Katoh, A., Nabeshima, T. & Kameyama, T., 01-01-1990, In : Journal of Pharmacology and Experimental Therapeutics. 253, 2, p. 600-607 8 p.

Research output: Contribution to journalArticle

Dynorphins
Enkephalins
dynorphin (1-8)
Leucine
Methionine
30 Citations (Scopus)

Cerebral hemodynamics in patients with chronic obstructive carotid disease by rCBF, rCBV, and rCBV/rCBF ratio using SPECT

Toyama, H., Takeshita, G., Takeuchi, A., Anno, H., Ejiri, K., Maeda, H., Katada, K., Koga, S., Ishiyama, N., Kanno, T. & Yamaoka, N., 01-01-1990, In : Journal of Nuclear Medicine. 31, 1, p. 55-60 6 p.

Research output: Contribution to journalArticle

Single-Photon Emission-Computed Tomography
Hemodynamics
Cerebrovascular Circulation
Lacunar Stroke
Carotid Stenosis
1 Citation (Scopus)

Changes in demand for hospital care of the elderly aged 75 or more

Nakanishi, N., Tadara, K., Nakagawa, Y., Nishi, N., Okamoto, E., Takaumo, T., Shinjo, F., Kurota, K., Tanaka, K. & Hashimoto, S., 01-08-1990, In : [Nippon koshu eisei zasshi] Japanese journal of public health. 37, 8, p. 610-619 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Characterization of gene organization and generation of heterogeneous mRNA species of rat ISK protein

Iwai, M., Masu, M., Tsuchida, K., Mori, T., Ohkubo, H. & Nakanishi, S., 01-01-1990, In : Journal of Biochemistry. 108, 2, p. 200-206 7 p.

Research output: Contribution to journalArticle

Rats
Genes
Messenger RNA
Proteins
Potassium Channels
34 Citations (Scopus)

Characterization of Recombinant Human Aromatic l‐Amino Acid Decarboxylase Expressed in COS Cells

Ichinose, C., Ichinose, H. & Nagatsu, T., 01-01-1990, In : Journal of Neurochemistry. 55, 3, p. 1075-1078 4 p.

Research output: Contribution to journalArticle

Carboxy-Lyases
COS Cells
Carboxylic acids
Complementary DNA
Pyridoxal Phosphate
5 Citations (Scopus)

Clinical application of 15-deoxyspergualin for treatment of acute graft rejection following renal transplantation

Suzuki, S., Hayashi, R., Kenmochi, T., Shimatani, K., Fukuoka, T. & Amemiya, H., 01-01-1990, In : Transplantation Proceedings. 22, 4, p. 1615-1617 3 p.

Research output: Contribution to journalArticle

Guanidines
Graft Rejection
Immunosuppressive Agents
Combination Drug Therapy
Kidney Transplantation
256 Citations (Scopus)

Cloning and expression of a rat neuromedin K receptor cDNA

Shigemoto, R., Yokota, Y., Tsuchida, K. & Nakanishi, S., 12-02-1990, In : Journal of Biological Chemistry. 265, 2, p. 623-628 6 p.

Research output: Contribution to journalArticle

Neurokinin-3 Receptors
Cloning
Neurokinin B
Rats
Organism Cloning