Find Research Outputs

2019

Essential points from Evidence-based Clinical Practice Guidelines for Chronic Kidney Disease 2018

Japanese Society of Nephrology, 22-01-2019, In : Clinical and Experimental Nephrology. 23, 1

Research output: Contribution to journalComment/debate

Evidence-Based Practice
Chronic Renal Insufficiency
Practice Guidelines
1 Citation (Scopus)

Establishment of a simpler method for measuring HDL-microRNAs

Ishikawa, H., Yamada, H., Kondo, K., Ota, T., Yamazaki, M., Ando, Y., Mizuno, G., Munetsuna, E., Suzuki, K., Teradaira, R. & Ohashi, K., 01-01-2019, In : Annals of Clinical Biochemistry. 56, 1, p. 49-55 7 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
MicroRNAs
Exosomes
Real-Time Polymerase Chain Reaction
Phosphotungstic Acid

Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity

El-Boraie, A., Taghavi, T., Chenoweth, M. J., Fukunaga, K., Mushiroda, T., Kubo, M., Lerman, C., Nollen, N. L., Benowitz, N. L. & Tyndale, R. F., 01-01-2019, In : Addiction Biology.

Research output: Contribution to journalArticle

Nicotine
Biomarkers
Cotinine
Phenotype
Smoking
Pancreatic Neoplasms
Nucleic Acids

Evaluation of the accelerate pheno system for identification of acinetobacter clinical isolates and minocycline susceptibility testing

Bowler, S. L., Towne, J. W., Humphries, R. M. & Doi, Y., 01-03-2019, In : Journal of clinical microbiology. 57, 3, e01711-18.

Research output: Contribution to journalArticle

Acinetobacter baumannii
Minocycline
Acinetobacter
Multiple Drug Resistance
Infection

Exhaled acetone and isoprene in perioperative lung cancer patients under intensive oral care: Possible indicators of inflammatory responses a nd metabolic changes

Tanda, N., Hoshikawa, Y., Sato, T., Takahashi, N. & Koseki, T., 01-01-2019, In : Biomedical Research (Japan). 40, 1, p. 29-36 8 p.

Research output: Contribution to journalArticle

Open Access
Critical Care
Acetone
Lung Neoplasms
Saliva
C-Reactive Protein
1 Citation (Scopus)

Factors affecting lower limb muscle strength and cardiopulmonary fitness after allogeneic hematopoietic stem cell transplantation

Ishikawa, A., Otaka, Y., Kamisako, M., Suzuki, T., Miyata, C., Tsuji, T., Matsumoto, H., Kato, J., Mori, T., Okamoto, S. & Liu, M., 01-05-2019, In : Supportive Care in Cancer. 27, 5, p. 1793-1800 8 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Muscle Strength
Lower Extremity
Torque
Leg

Fatal community-acquired Bacillus cereus pneumonia in an immunocompetent adult man: A case report

Ishida, R., Ueda, K., Kitano, T., Yamamoto, T., Mizutani, Y., Tsutsumi, Y., Imoto, K. & Yamamori, Y., 27-02-2019, In : BMC Infectious Diseases. 19, 1, 197.

Research output: Contribution to journalArticle

Open Access
Bacillus cereus
Pneumonia
Bioterrorism
Anthrax
Gram-Positive Rods
3 Citations (Scopus)

Feasibility of early multimodal interventions for elderly patients with advanced pancreatic and non-small-cell lung cancer

Naito, T., Mitsunaga, S., Miura, S., Tatematsu, N., Inano, T., Mouri, T., Tsuji, T., Higashiguchi, T., Inui, A., Okayama, T., Yamaguchi, T., Morikawa, A., Mori, N., Takahashi, T., Strasser, F., Omae, K., Mori, K. & Takayama, K., 01-02-2019, In : Journal of Cachexia, Sarcopenia and Muscle. 10, 1, p. 73-83 11 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Exercise
Compliance
Counseling
Neoplasms

Fluoroquinolone Prophylaxis Selects for Meropenem-nonsusceptible Pseudomonas aeruginosa in Patients With Hematologic Malignancies and Hematopoietic Cell Transplant Recipients

Hakki, M., Humphries, R. M., Hemarajata, P., Tallman, G. B., Shields, R. K., Mettus, R. T., Doi, Y. & Lewis, J. S., 30-05-2019, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 68, 12, p. 2045-2052 8 p.

Research output: Contribution to journalArticle

meropenem
Fluoroquinolones
Hematologic Neoplasms
Pseudomonas aeruginosa
Transplants

Fluoxetine-induced dematuration of hippocampal neurons and adult cortical neurogenesis in the common marmoset

Ohira, K., Hagihara, H., Miwa, M., Nakamura, K. & Miyakawa, T., 05-08-2019, In : Molecular brain. 12, 1, 69.

Research output: Contribution to journalArticle

Open Access
Callithrix
Fluoxetine
Neurogenesis
Neurons
Interneurons
Fosfomycin
Urinary Tract Infections
Bacteria
Therapeutics
1 Citation (Scopus)
Percutaneous Coronary Intervention
Myocardial Infarction
Optical Coherence Tomography
Angiography
Registries

Frequent intragenic microdeletions of elastin in familial supravalvular aortic stenosis

Hayano, S., Okuno, Y., Tsutsumi, M., Inagaki, H., Fukasawa, Y., Kurahashi, H., Kojima, S., Takahashi, Y. & Kato, T., 01-01-2019, In : International Journal of Cardiology. 274, p. 290-295 6 p.

Research output: Contribution to journalArticle

Supravalvular Aortic Stenosis
Elastin
Exome
Mutation
Williams Syndrome

Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas

Kataoka, K., Miyoshi, H., Sakata, S., Dobashi, A., Couronné, L., Kogure, Y., Sato, Y., Nishida, K., Gion, Y., Shiraishi, Y., Tanaka, H., Chiba, K., Watatani, Y., Kakiuchi, N., Shiozawa, Y., Yoshizato, T., Yoshida, K., Makishima, H., Sanada, M., Onozawa, M. & 18 others, Teshima, T., Yoshiki, Y., Ishida, T., Suzuki, K., Shimada, K., Tomita, A., Kato, M., Ota, Y., Izutsu, K., Demachi-Okamura, A., Akatsuka, Y., Miyano, S., Yoshino, T., Gaulard, P., Hermine, O., Takeuchi, K., Ohshima, K. & Ogawa, S., 01-07-2019, In : Leukemia. 33, 7, p. 1687-1699 13 p.

Research output: Contribution to journalArticle

Open Access
Human Herpesvirus 4
Lymphoma
Ligands
Extranodal NK-T-Cell Lymphoma
Large Granular Lymphocytic Leukemia

Gastrointestinal bleeding with severe mucosal involvement in a patient with generalized pustular psoriasis without IL36RN mutation

Komatsuda, S., Kamata, M., Chijiwa, C., Namiki, K., Fukaya, S., Hayashi, K., Fukuyasu, A., Tanaka, T., Ishikawa, T., Ohnishi, T., Abe, K., Yamamoto, T., Aozasa, N., Sugiura, K. & Tada, Y., 01-01-2019, In : Journal of Dermatology. 46, 1, p. 73-75 3 p.

Research output: Contribution to journalArticle

Psoriasis
Hemorrhage
Mutation
Erythema
Tongue
3 Citations (Scopus)

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

iPSYCH-GEMS Schizophrenia Working Group, CommonMind Consortium & The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium, 01-04-2019, In : Nature Genetics. 51, 4, p. 659-674 16 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Prefrontal Cortex
Schizophrenia
Tay-Sachs Disease
Gene Expression

Generalized pustular psoriasis from heterozygous IL36RN mutation developed after liver surgery

Fukushima, H., Iwata, Y., Numata, S., Saito, K., Watanabe, S., Kobayashi, T. & Sugiura, K., 01-01-2019, In : Journal of Dermatology. 46, 8, p. e301-e302

Research output: Contribution to journalLetter

Psoriasis
Mutation
Liver

Generation of infectious recombinant human rotaviruses from just 11 cloned cDNAs encoding the rotavirus genome

Komoto, S., Fukuda, S., Kugita, M., Hatazawa, R., Koyama, C., Katayama, K., Murata, T. & Taniguchi, K., 01-01-2019, In : Journal of Virology. 93, 8, Y.

Research output: Contribution to journalArticle

Rotavirus
Complementary DNA
Genome
genome
plasmids
1 Citation (Scopus)

Genetic and phenotypic landscape of the major histocompatibilty complex region in the Japanese population

Hirata, J., Hosomichi, K., Sakaue, S., Kanai, M., Nakaoka, H., Ishigaki, K., Suzuki, K., Akiyama, M., Kishikawa, T., Ogawa, K., Masuda, T., Yamamoto, K., Hirata, M., Matsuda, K., Momozawa, Y., Inoue, I., Kubo, M., Kamatani, Y. & Okada, Y., 01-03-2019, In : Nature Genetics. 51, 3, p. 470-480 11 p.

Research output: Contribution to journalArticle

HLA Antigens
Phenotype
Population
Genes
Genome-Wide Association Study

Genetic effects on white matter integrity in drug-naive patients with major depressive disorder: A diffusion tensor imaging study of 17 genetic loci associated with depressive symptoms

Kakeda, S., Watanabe, K., Katsuki, A., Sugimoto, K., Ueda, I., Igata, N., Kishi, T., Iwata, N., Abe, O., Yoshimura, R. & Korogi, Y., 01-01-2019, In : Neuropsychiatric Disease and Treatment. 15, p. 375-383 9 p.

Research output: Contribution to journalArticle

Open Access
Diffusion Tensor Imaging
Genetic Loci
Major Depressive Disorder
Depression
Single Nucleotide Polymorphism
1 Citation (Scopus)

Genome-wide association analysis of common genetic variants of resistant hypertension

on behalf of eMERGE network, 01-06-2019, In : Pharmacogenomics Journal. 19, 3, p. 295-304 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Hypertension
Odds Ratio
trandolapril
Hispanic Americans

Genome-Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol

Brackman, D. J., Yee, S. W., Enogieru, O. J., Shaffer, C., Ranatunga, D., Denny, J. C., Wei, W. Q., Kamatani, Y., Kubo, M., Roden, D. M., Jorgenson, E. & Giacomini, K. M., 01-01-2019, In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Allopurinol
Genome-Wide Association Study
Pharmacology
Oxypurinol
Uric Acid

Genome-wide association study identifies a novel locus associated with psychological distress in the Japanese population

Koshimizu, H., Nogawa, S., Asano, S., Ikeda, M., Iwata, N., Takahashi, S., Saito, K. & Miyakawa, T., 01-12-2019, In : Translational psychiatry. 9, 1, 52.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Major Depressive Disorder
Psychology
Population
Far East

Genome-wide association study of cervical cancer suggests a role for ARRDC3 gene in human papillomavirus infection

Takeuchi, F., Kukimoto, I., Li, Z., Li, S., Li, N., Hu, Z., Takahashi, A., Inoue, S., Yokoi, S., Chen, J., Hang, D., Kuroda, M., Matsuda, F., Mizuno, M., Mori, S., Wu, P., Tanaka, N., Matsuo, K., Kamatani, Y., Kubo, M. & 2 others, Ma, D. & Shi, Y., 15-01-2019, In : Human molecular genetics. 28, 2, p. 341-348 8 p.

Research output: Contribution to journalArticle

Arrestin
Papillomavirus Infections
Genome-Wide Association Study
Uterine Cervical Neoplasms
Single Nucleotide Polymorphism

Genomic characterization of uncommon human G3P[6] rotavirus strains that have emerged in Kenya after rotavirus vaccine introduction, and pre-vaccine human G8P[4] rotavirus strains

Wandera, E. A., Komoto, S., Mohammad, S., Ide, T., Bundi, M., Nyangao, J., Kathiiko, C., Odoyo, E., Galata, A., Miring'u, G., Fukuda, S., Hatazawa, R., Murata, T., Taniguchi, K. & Ichinose, Y., 01-03-2019, In : Infection, Genetics and Evolution. 68, p. 231-248 18 p.

Research output: Contribution to journalArticle

Rotavirus Vaccines
Rotavirus
Kenya
vaccine
genomics
4 Citations (Scopus)

Genomic Heterogeneity Within Individual Prostate Cancer Foci Impacts Predictive Biomarkers of Targeted Therapy

VanderWeele, D. J., Finney, R., Katayama, K., Gillard, M., Paner, G., Imoto, S., Yamaguchi, R., Wheeler, D., Lack, J., Cam, M., Pontier, A., Nguyen, Y. T. M., Maejima, K., Sasaki-Oku, A., Nakano, K., Tanaka, H., Vander Griend, D., Kubo, M., Ratain, M. J., Miyano, S. & 1 others, Nakagawa, H., 01-05-2019, In : European Urology Focus. 5, 3, p. 416-424 9 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Biomarkers
Therapeutics
Exome
Survival
12 Citations (Scopus)

GLIM Criteria for the Diagnosis of Malnutrition: A Consensus Report From the Global Clinical Nutrition Community

Jensen, G. L., Cederholm, T., Correia, M. I. T. D., Gonzalez, M. C., Fukushima, R., Higashiguchi, T., de Baptista, G. A., Barazzoni, R., Blaauw, R., Coats, A. J. S., Crivelli, A., Evans, D. C., Gramlich, L., Fuchs-Tarlovsky, V., Keller, H., Llido, L., Malone, A., Mogensen, K. M., Morley, J. E., Muscaritoli, M. & 13 others, Nyulasi, I., Pirlich, M., Pisprasert, V., de van der Schueren, M., Siltharm, S., Singer, P., Tappenden, K. A., Velasco, N., Waitzberg, D. L., Yamwong, P., Yu, J., Compher, C. & Van Gossum, A., 01-01-2019, In : Journal of Parenteral and Enteral Nutrition. 43, 1, p. 32-40 9 p.

Research output: Contribution to journalArticle

Malnutrition
Consensus
Sarcopenia
Cachexia
Validation Studies
3 Citations (Scopus)

GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community

GLIM Core Leadership Committee, GLIM Working Group, 01-02-2019, In : Journal of Cachexia, Sarcopenia and Muscle. 10, 1, p. 207-217 11 p.

Research output: Contribution to journalArticle

Open Access
Malnutrition
Consensus
Sarcopenia
Cachexia
Validation Studies
42 Citations (Scopus)

GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community

GLIM Core Leadership Committee & GLIM Working Group, 01-02-2019, In : Clinical Nutrition. 38, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Open Access
Malnutrition
Consensus
Sarcopenia
Cachexia
Validation Studies
13 Citations (Scopus)

Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

GBD 2016 Neurology Collaborators, 01-05-2019, In : The Lancet Neurology. 18, 5, p. 459-480 22 p.

Research output: Contribution to journalArticle

Open Access
Nervous System Diseases
Migraine Disorders
Meningitis
Cause of Death
Tension-Type Headache
12 Citations (Scopus)

Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

GBD 2016 Stroke Collaborators, 01-05-2019, In : The Lancet Neurology. 18, 5, p. 439-458 20 p.

Research output: Contribution to journalArticle

Open Access
Stroke
Quality-Adjusted Life Years
Demography
Mortality
Uncertainty

Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult

Mohiuddin, M. S., Himeno, T., Inoue, R., Miura-Yura, E., Yamada, Y., Nakai-Shimoda, H., Asano, S., Kato, M., Motegi, M., Kondo, M., Seino, Y., Tsunekawa, S., Kato, Y., Suzuki, A., Naruse, K., Kato, K., Nakamura, J. & Kamiya, H., 01-01-2019, In : Journal of Diabetes Research. 2019, 9426014.

Research output: Contribution to journalArticle

Open Access
Diabetic Neuropathies
Spinal Ganglia
Neurons
Neurites
Cyclic AMP

Greater Nutrient Intake Is Associated With Lower Mortality in Western and Eastern Critically Ill Patients With Low BMI: A Multicenter, Multinational Observational Study

Compher, C., Chittams, J., Sammarco, T., Higashibeppu, N., Higashiguchi, T. & Heyland, D. K., 01-01-2019, In : Journal of Parenteral and Enteral Nutrition. 43, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

Critical Illness
Observational Studies
Body Mass Index
Food
Mortality
1 Citation (Scopus)

Group-level and functional-region analysis of electric-field shape during cerebellar transcranial direct current stimulation with different electrode montages

Gomez-Tames, J., Asai, A., Mikkonen, M., Laakso, I., Tanaka, S., Uehara, S., Otaka, Y. & Hirata, A., 01-01-2019, In : Journal of Neural Engineering. 16, 3, 036001.

Research output: Contribution to journalArticle

Electrodes
Electric fields
Cerebellum
Atlases
Cerebrospinal fluid
1 Citation (Scopus)

Guidelines for office gynecology in Japan: Japan Society of Obstetrics and Gynecology (JSOG) and Japan Association of Obstetricians and Gynecologists (JAOG) 2017 edition

Kawaguchi, R., Matsumoto, K., Akira, S., Ishitani, K., Iwasaku, K., Ueda, Y., Okagaki, R., Okano, H., Oki, T., Koga, K., Kido, M., Kurabayashi, T., Kuribayashi, Y., Sato, Y., Shiina, K., Takai, Y., Tanimura, S., Chaki, O., Terauchi, M., Todo, Y. & 14 others, Noguchi, Y., Nose-Ogura, S., Baba, T., Hirasawa, A., Fujii, T., Fujii, T., Maruyama, T., Miyagi, E., Yanagida, K., Yoshino, O., Iwashita, M., Maeda, T., Minegishi, T. & Kobayashi, H., 01-04-2019, In : Journal of Obstetrics and Gynaecology Research. 45, 4, p. 766-786 21 p.

Research output: Contribution to journalArticle

Gynecology
Obstetrics
Japan
Guidelines
Endocrinology
3 Citations (Scopus)

Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease

Kikuchi, K., Saigusa, D., Kanemitsu, Y., Matsumoto, Y., Thanai, P., Suzuki, N., Mise, K., Yamaguchi, H., Nakamura, T., Asaji, K., Mukawa, C., Tsukamoto, H., Sato, T., Oikawa, Y., Iwasaki, T., Oe, Y., Tsukimi, T., Fukuda, N. N., Ho, H. J., Nanto-Hara, F. & 36 others, Ogura, J., Saito, R., Nagao, S., Ohsaki, Y., Shimada, S., Suzuki, T., Toyohara, T., Mishima, E., Shima, H., Akiyama, Y., Akiyama, Y., Ichijo, M., Matsuhashi, T., Matsuo, A., Ogata, Y., Yang, C. C., Suzuki, C., Breeggemann, M. C., Heymann, J., Shimizu, M., Ogawa, S., Takahashi, N., Suzuki, T., Owada, Y., Kure, S., Mano, N., Soga, T., Wada, T., Kopp, J. B., Fukuda, S., Hozawa, A., Yamamoto, M., Ito, S., Wada, J., Tomioka, Y. & Abe, T., 01-12-2019, In : Nature Communications. 10, 1, 1835.

Research output: Contribution to journalArticle

Open Access
kidney diseases
Albuminuria
Diabetic Nephropathies
Sulfates
sulfates

GWAS analysis reveals a significant contribution of PSCA to the risk of Heliobacter pylori-induced gastric atrophy

Hishida, A., Ugai, T., Fujii, R., Nakatochi, M., Wu, M. C., Ito, H., Oze, I., Tajika, M., Niwa, Y., Nishiyama, T., Nakagawa-Senda, H., Suzuki, S., Koyama, T., Matsui, D., Watanabe, Y., Kawaguchi, T., Matsuda, F., Momozawa, Y., Kubo, M., Naito, M. & 2 others, Matsuo, K. & Wakai, K., 04-07-2019, In : Carcinogenesis. 40, 5, p. 661-668 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Pylorus
Atrophy
Prostate
Stomach

GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture

Matoba, N., Akiyama, M., Ishigaki, K., Kanai, M., Takahashi, A., Momozawa, Y., Ikegawa, S., Ikeda, M., Iwata, N., Hirata, M., Matsuda, K., Kubo, M., Okada, Y. & Kamatani, Y., 01-05-2019, In : Nature Human Behaviour. 3, 5, p. 471-477 7 p.

Research output: Contribution to journalLetter

Genetic Loci
Genome-Wide Association Study
Smoking
Linkage Disequilibrium
Tobacco Products

High-fat and high-cholesterol diet decreases phosphorylated inositol-requiring kinase-1 and inhibits autophagy process in rat liver

Naito, H., Yoshikawa-Bando, Y., Yuan, Y., Hashimoto, S., Kitamori, K., Yatsuya, H. & Nakajima, T., 01-12-2019, In : Scientific reports. 9, 1, 12514.

Research output: Contribution to journalArticle

Open Access
Autophagy
High Fat Diet
Inositol
Phosphotransferases
Cholesterol

Histopathological classification of anti-neutrophil cytoplasmic antibody-associated glomerulonephritis in a nationwide Japanese prospective 2-year follow-up cohort study

For the Research Committee of Intractable Renal Disease and the Research Committee of Intractable Vasculitis Syndrome of the Ministry of Health, Labour, and Welfare of Japan, 15-03-2019, In : Clinical and Experimental Nephrology. 23, 3, p. 387-394 8 p.

Research output: Contribution to journalArticle

Antineutrophil Cytoplasmic Antibodies
Glomerulonephritis
Cohort Studies
Kidney
Glomerular Filtration Rate

HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease

Shimizu, C., Kim, J., Eleftherohorinou, H., Wright, V. J., Hoang, L. T., Tremoulet, A. H., Franco, A., Hibberd, M. L., Takahashi, A., Kubo, M., Ito, K., Tanaka, T., Onouchi, Y., Coin, L. J. M., Levin, M., Burns, J. C. & Shike, H., 01-01-2019, In : Human Immunology.

Research output: Contribution to journalArticle

HLA-C Antigens
Mucocutaneous Lymph Node Syndrome
Amino Acid Substitution
Peptides
Alleles

Human serum albumin redox state is associated with decreased renal function in a community-dwelling population

Fujii, R., Ueyama, J., Kanno, T., Suzuki, K., Hamajima, N., Wakai, K., Hasegawa, Y. & Kondo, T., 01-01-2019, In : American journal of physiology. Renal physiology. 316, 1, p. F214-F218

Research output: Contribution to journalArticle

Independent Living
Serum Albumin
Oxidation-Reduction
Kidney
Population
1 Citation (Scopus)

Human tyrosine hydroxylase in Parkinson’s disease and in related disorders

Nagatsu, T., Nakashima, A., Ichinose, H. & Kobayashi, K., 01-04-2019, In : Journal of Neural Transmission. 126, 4, p. 397-409 13 p.

Research output: Contribution to journalReview article

Tyrosine 3-Monooxygenase
Parkinson Disease
Dopaminergic Neurons
Dopamine
Corpus Striatum

Hyoid Bone Movement at Rest by Peripheral Magnetic Stimulation of Suprahyoid Muscles in Normal Individuals

Kagaya, H., Ogawa, M., Mori, S., Aoyagi, Y., Shibata, S., Inamoto, Y., Mori, H. & Saito, E., 01-07-2019, In : Neuromodulation. 22, 5, p. 593-596 4 p.

Research output: Contribution to journalArticle

Hyoid Bone
Muscles
Pain
Fluoroscopy
Deglutition Disorders

Identification by nano-LC-MS/MS of NT5DC2 as a protein binding to tyrosine hydroxylase: Down-regulation of NT5DC2 by siRNA increases catecholamine synthesis in PC12D cells

Nakashima, A., Yamaguchi, H., Kodani, Y., Kaneko, Y. S., Kawata, M., Nagasaki, H., Nagatsu, T. & Ota, A., 03-09-2019, In : Biochemical and Biophysical Research Communications. 516, 4, p. 1060-1065 6 p.

Research output: Contribution to journalArticle

Tyrosine 3-Monooxygenase
Protein Binding
Small Interfering RNA
Catecholamines
Down-Regulation
4 Citations (Scopus)

Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population

Suzuki, K., Akiyama, M., Ishigaki, K., Kanai, M., Hosoe, J., Shojima, N., Hozawa, A., Kadota, A., Kuriki, K., Naito, M., Tanno, K., Ishigaki, Y., Hirata, M., Matsuda, K., Iwata, N., Ikeda, M., Sawada, N., Yamaji, T., Iwasaki, M., Ikegawa, S. & 12 others, Maeda, S., Murakami, Y., Wakai, K., Tsugane, S., Sasaki, M., Yamamoto, M., Okada, Y., Kubo, M., Kamatani, Y., Horikoshi, M., Yamauchi, T. & Kadowaki, T., 01-03-2019, In : Nature Genetics. 51, 3, p. 379-386 8 p.

Research output: Contribution to journalLetter

Genome-Wide Association Study
Gene Frequency
Type 2 Diabetes Mellitus
Population
Acinar Cells
1 Citation (Scopus)

Identification of marker genes and pathways specific to precancerous duodenal adenomas and early stage adenocarcinomas

Sakaguchi, Y., Yamamichi, N., Tomida, S., Takeuchi, C., Kageyama-Yahara, N., Takahashi, Y., Shiogama, K., Inada, K. I., Ichinose, M., Fujishiro, M. & Koike, K., 15-02-2019, In : Journal of Gastroenterology. 54, 2, p. 131-140 10 p.

Research output: Contribution to journalArticle

Adenoma
Adenocarcinoma
Catenins
Genes
Gene Expression

Identification of rare coding variants in TYK2 protective for rheumatoid arthritis in the Japanese population and their effects on cytokine signalling

Motegi, T., Kochi, Y., Matsuda, K., Kubo, M., Yamamoto, K. & Momozawa, Y., 01-01-2019, In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Rheumatoid Arthritis
Genes
Association reactions
Cytokines
Interferons

IgA1 hinge-region clustered glycan fidelity is established early during semi-ordered glycosylation by GalNAc-T2

Stewart, T. J., Takahashi, K., Whitaker, R. H., Raska, M., Placzek, W. J., Novak, J. & Renfrow, M. B., 01-01-2019, In : Glycobiology. 29, 7, p. 543-556 14 p., cwz007.

Research output: Contribution to journalArticle

Glycosylation
Hinges
Immunoglobulin A
Polysaccharides
Site selection