Find Research Outputs

2019
3 Citations (Scopus)

Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas

Kataoka, K., Miyoshi, H., Sakata, S., Dobashi, A., Couronné, L., Kogure, Y., Sato, Y., Nishida, K., Gion, Y., Shiraishi, Y., Tanaka, H., Chiba, K., Watatani, Y., Kakiuchi, N., Shiozawa, Y., Yoshizato, T., Yoshida, K., Makishima, H., Sanada, M., Onozawa, M. & 18 others, Teshima, T., Yoshiki, Y., Ishida, T., Suzuki, K., Shimada, K., Tomita, A., Kato, M., Ota, Y., Izutsu, K., Demachi-Okamura, A., Akatsuka, Y., Miyano, S., Yoshino, T., Gaulard, P., Hermine, O., Takeuchi, K., Ohshima, K. & Ogawa, S., 01-07-2019, In : Leukemia. 33, 7, p. 1687-1699 13 p.

Research output: Contribution to journalArticle

Open Access
Human Herpesvirus 4
Lymphoma
Ligands
Extranodal NK-T-Cell Lymphoma
Large Granular Lymphocytic Leukemia

Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population

Sakaue, S., Akiyama, M., Hirata, M., Matsuda, K., Murakami, Y., Kubo, M., Kamatani, Y. & Okada, Y., 01-01-2019, (Accepted/In press) In : European Journal of Human Genetics.

Research output: Contribution to journalArticle

Open Access
Alleles
Genotype
Mortality
Population
Survival Analysis

Gastric Mucosal Microarchitectures Associated with Irreversibility with Helicobacter pylori Eradication and Downregulation of Micro RNA (miR)-124a

Tahara, T., Tahara, S., Horiguchi, N., Kawamura, T., Okubo, M., Nagasaka, M., Nakagawa, Y., Shibata, T., Urano, M., Tsukamoto, T., Kuroda, M. & Ohmiya, N., 21-10-2019, In : Cancer Investigation. 37, 9, p. 417-426 10 p.

Research output: Contribution to journalArticle

MicroRNAs
Helicobacter pylori
Stomach
Down-Regulation
Narrow Band Imaging
1 Citation (Scopus)

Gastrointestinal bleeding with severe mucosal involvement in a patient with generalized pustular psoriasis without IL36RN mutation

Komatsuda, S., Kamata, M., Chijiwa, C., Namiki, K., Fukaya, S., Hayashi, K., Fukuyasu, A., Tanaka, T., Ishikawa, T., Ohnishi, T., Abe, K., Yamamoto, T., Aozasa, N., Sugiura, K. & Tada, Y., 01-01-2019, In : Journal of Dermatology. 46, 1, p. 73-75 3 p.

Research output: Contribution to journalArticle

Psoriasis
Hemorrhage
Mutation
Erythema
Tongue
8 Citations (Scopus)

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

CommonMind Consortium, The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium & iPSYCH-GEMS Schizophrenia Working Group, 01-04-2019, In : Nature Genetics. 51, 4, p. 659-674 16 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Prefrontal Cortex
Schizophrenia
Tay-Sachs Disease
Gene Expression

Generalized pustular psoriasis from heterozygous IL36RN mutation developed after liver surgery

Fukushima, H., Iwata, Y., Numata, S., Saito, K., Watanabe, S., Kobayashi, T. & Sugiura, K., 01-01-2019, In : Journal of Dermatology. 46, 8, p. e301-e302

Research output: Contribution to journalLetter

Psoriasis
Mutation
Liver

Generation of infectious recombinant human rotaviruses from just 11 cloned cDNAs encoding the rotavirus genome

Komoto, S., Fukuda, S., Kugita, M., Hatazawa, R., Koyama, C., Katayama, K., Murata, T. & Taniguchi, K., 01-01-2019, In : Journal of Virology. 93, 8, Y.

Research output: Contribution to journalArticle

Rotavirus
Complementary DNA
Genome
genome
plasmids
6 Citations (Scopus)

Genetic and phenotypic landscape of the major histocompatibilty complex region in the Japanese population

Hirata, J., Hosomichi, K., Sakaue, S., Kanai, M., Nakaoka, H., Ishigaki, K., Suzuki, K., Akiyama, M., Kishikawa, T., Ogawa, K., Masuda, T., Yamamoto, K., Hirata, M., Matsuda, K., Momozawa, Y., Inoue, I., Kubo, M., Kamatani, Y. & Okada, Y., 01-03-2019, In : Nature Genetics. 51, 3, p. 470-480 11 p.

Research output: Contribution to journalArticle

HLA Antigens
Phenotype
Population
Genes
Genome-Wide Association Study
1 Citation (Scopus)

Genetic effects on white matter integrity in drug-naive patients with major depressive disorder: A diffusion tensor imaging study of 17 genetic loci associated with depressive symptoms

Kakeda, S., Watanabe, K., Katsuki, A., Sugimoto, K., Ueda, I., Igata, N., Kishi, T., Iwata, N., Abe, O., Yoshimura, R. & Korogi, Y., 01-01-2019, In : Neuropsychiatric Disease and Treatment. 15, p. 375-383 9 p.

Research output: Contribution to journalArticle

Open Access
Diffusion Tensor Imaging
Genetic Loci
Major Depressive Disorder
Depression
Single Nucleotide Polymorphism
1 Citation (Scopus)

Genome-wide association analysis of common genetic variants of resistant hypertension

on behalf of eMERGE network, 01-06-2019, In : Pharmacogenomics Journal. 19, 3, p. 295-304 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Hypertension
Odds Ratio
trandolapril
Hispanic Americans
2 Citations (Scopus)

Genome-Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol

Brackman, D. J., Yee, S. W., Enogieru, O. J., Shaffer, C., Ranatunga, D., Denny, J. C., Wei, W. Q., Kamatani, Y., Kubo, M., Roden, D. M., Jorgenson, E. & Giacomini, K. M., 01-01-2019, In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Allopurinol
Genome-Wide Association Study
Pharmacology
Oxypurinol
Uric Acid
1 Citation (Scopus)

Genome-wide association studies identify polygenic effects for completed suicide in the Japanese population

Otsuka, I., Akiyama, M., Shirakawa, O., Okazaki, S., Momozawa, Y., Kamatani, Y., Izumi, T., Numata, S., Takahashi, M., Boku, S., Sora, I., Yamamoto, K., Ueno, Y., Toda, T., Kubo, M. & Hishimoto, A., 01-11-2019, In : Neuropsychopharmacology. 44, 12, p. 2119-2124 6 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Suicide
Population
Single Nucleotide Polymorphism
Japan
4 Citations (Scopus)

Genome-wide association study detected novel susceptibility genes for schizophrenia and shared trans-populations/diseases genetic effect

Ikeda, M., Takahashi, A., Kamatani, Y., Momozawa, Y., Saito, T., Kondo, K., Shimasaki, A., Kawase, K., Sakusabe, T., Iwayama, Y., Toyota, T., Wakuda, T., Kikuchi, M., Kanahara, N., Yamamori, H., Yasuda, Y., Watanabe, Y., Hoya, S., Aleksic, B., Kushima, I. & 12 others, Arai, H., Takaki, M., Hattori, K., Kunugi, H., Okahisa, Y., Ohnuma, T., Ozaki, N., Someya, T., Hashimoto, R., Yoshikawa, T., Kubo, M. & Iwata, N., 01-01-2019, In : Schizophrenia Bulletin. 45, 4, p. 824-834 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Population Genetics
Schizophrenia
Genes
Bipolar Disorder

Genome-wide association study identifies a novel locus associated with psychological distress in the Japanese population

Koshimizu, H., Nogawa, S., Asano, S., Ikeda, M., Iwata, N., Takahashi, S., Saito, K. & Miyakawa, T., 01-12-2019, In : Translational psychiatry. 9, 1, 52.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Major Depressive Disorder
Psychology
Population
Far East
1 Citation (Scopus)

Genome-wide association study of cervical cancer suggests a role for ARRDC3 gene in human papillomavirus infection

Takeuchi, F., Kukimoto, I., Li, Z., Li, S., Li, N., Hu, Z., Takahashi, A., Inoue, S., Yokoi, S., Chen, J., Hang, D., Kuroda, M., Matsuda, F., Mizuno, M., Mori, S., Wu, P., Tanaka, N., Matsuo, K., Kamatani, Y., Kubo, M. & 2 others, Ma, D. & Shi, Y., 15-01-2019, In : Human molecular genetics. 28, 2, p. 341-348 8 p.

Research output: Contribution to journalArticle

Arrestin
Papillomavirus Infections
Genome-Wide Association Study
Uterine Cervical Neoplasms
Single Nucleotide Polymorphism

Genomic characterization of uncommon human G3P[6] rotavirus strains that have emerged in Kenya after rotavirus vaccine introduction, and pre-vaccine human G8P[4] rotavirus strains

Wandera, E. A., Komoto, S., Mohammad, S., Ide, T., Bundi, M., Nyangao, J., Kathiiko, C., Odoyo, E., Galata, A., Miring'u, G., Fukuda, S., Hatazawa, R., Murata, T., Taniguchi, K. & Ichinose, Y., 03-2019, In : Infection, Genetics and Evolution. 68, p. 231-248 18 p.

Research output: Contribution to journalArticle

Rotavirus Vaccines
Rotavirus
Kenya
vaccine
genomics
4 Citations (Scopus)

Genomic Heterogeneity Within Individual Prostate Cancer Foci Impacts Predictive Biomarkers of Targeted Therapy

VanderWeele, D. J., Finney, R., Katayama, K., Gillard, M., Paner, G., Imoto, S., Yamaguchi, R., Wheeler, D., Lack, J., Cam, M., Pontier, A., Nguyen, Y. T. M., Maejima, K., Sasaki-Oku, A., Nakano, K., Tanaka, H., Vander Griend, D., Kubo, M., Ratain, M. J., Miyano, S. & 1 others, Nakagawa, H., 05-2019, In : European Urology Focus. 5, 3, p. 416-424 9 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Biomarkers
Therapeutics
Exome
Survival
32 Citations (Scopus)

GLIM Criteria for the Diagnosis of Malnutrition: A Consensus Report From the Global Clinical Nutrition Community

Jensen, G. L., Cederholm, T., Correia, M. I. T. D., Gonzalez, M. C., Fukushima, R., Higashiguchi, T., de Baptista, G. A., Barazzoni, R., Blaauw, R., Coats, A. J. S., Crivelli, A., Evans, D. C., Gramlich, L., Fuchs-Tarlovsky, V., Keller, H., Llido, L., Malone, A., Mogensen, K. M., Morley, J. E., Muscaritoli, M. & 13 others, Nyulasi, I., Pirlich, M., Pisprasert, V., de van der Schueren, M., Siltharm, S., Singer, P., Tappenden, K. A., Velasco, N., Waitzberg, D. L., Yamwong, P., Yu, J., Compher, C. & Van Gossum, A., 01-2019, In : Journal of Parenteral and Enteral Nutrition. 43, 1, p. 32-40 9 p.

Research output: Contribution to journalArticle

Malnutrition
Consensus
Sarcopenia
Cachexia
Validation Studies
78 Citations (Scopus)

GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community

GLIM Core Leadership Committee & GLIM Working Group, 02-2019, In : Clinical Nutrition. 38, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Open Access
Malnutrition
Consensus
Sarcopenia
Cachexia
Validation Studies
11 Citations (Scopus)

GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community

GLIM Core Leadership Committee, GLIM Working Group, 02-2019, In : Journal of Cachexia, Sarcopenia and Muscle. 10, 1, p. 207-217 11 p.

Research output: Contribution to journalArticle

Open Access
Malnutrition
Consensus
Sarcopenia
Cachexia
Validation Studies
35 Citations (Scopus)

Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

GBD 2016 Neurology Collaborators, 05-2019, In : The Lancet Neurology. 18, 5, p. 459-480 22 p.

Research output: Contribution to journalArticle

Open Access
Nervous System Diseases
Migraine Disorders
Meningitis
Cause of Death
Tension-Type Headache
27 Citations (Scopus)

Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

GBD 2016 Stroke Collaborators, 05-2019, In : The Lancet Neurology. 18, 5, p. 439-458 20 p.

Research output: Contribution to journalArticle

Open Access
Stroke
Quality-Adjusted Life Years
Demography
Mortality
Uncertainty

Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult

Mohiuddin, M. S., Himeno, T., Inoue, R., Miura-Yura, E., Yamada, Y., Nakai-Shimoda, H., Asano, S., Kato, M., Motegi, M., Kondo, M., Seino, Y., Tsunekawa, S., Kato, Y., Suzuki, A., Naruse, K., Kato, K., Nakamura, J. & Kamiya, H., 01-01-2019, In : Journal of Diabetes Research. 2019, 9426014.

Research output: Contribution to journalArticle

Open Access
Diabetic Neuropathies
Spinal Ganglia
Neurons
Neurites
Cyclic AMP
5 Citations (Scopus)

Greater Nutrient Intake Is Associated With Lower Mortality in Western and Eastern Critically Ill Patients With Low BMI: A Multicenter, Multinational Observational Study

Compher, C., Chittams, J., Sammarco, T., Higashibeppu, N., Higashiguchi, T. & Heyland, D. K., 01-2019, In : Journal of Parenteral and Enteral Nutrition. 43, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

Critical Illness
Observational Studies
Body Mass Index
Food
Mortality
2 Citations (Scopus)

Group-level and functional-region analysis of electric-field shape during cerebellar transcranial direct current stimulation with different electrode montages

Gomez-Tames, J., Asai, A., Mikkonen, M., Laakso, I., Tanaka, S., Uehara, S., Otaka, Y. & Hirata, A., 01-01-2019, In : Journal of Neural Engineering. 16, 3, 036001.

Research output: Contribution to journalArticle

Electrodes
Electric fields
Cerebellum
Atlases
Cerebrospinal fluid
5 Citations (Scopus)

Guidelines for office gynecology in Japan: Japan Society of Obstetrics and Gynecology (JSOG) and Japan Association of Obstetricians and Gynecologists (JAOG) 2017 edition

Kawaguchi, R., Matsumoto, K., Akira, S., Ishitani, K., Iwasaku, K., Ueda, Y., Okagaki, R., Okano, H., Oki, T., Koga, K., Kido, M., Kurabayashi, T., Kuribayashi, Y., Sato, Y., Shiina, K., Takai, Y., Tanimura, S., Chaki, O., Terauchi, M., Todo, Y. & 14 others, Noguchi, Y., Nose-Ogura, S., Baba, T., Hirasawa, A., Fujii, T., Fujii, T., Maruyama, T., Miyagi, E., Yanagida, K., Yoshino, O., Iwashita, M., Maeda, T., Minegishi, T. & Kobayashi, H., 01-04-2019, In : Journal of Obstetrics and Gynaecology Research. 45, 4, p. 766-786 21 p.

Research output: Contribution to journalArticle

Gynecology
Obstetrics
Japan
Guidelines
Endocrinology
6 Citations (Scopus)

Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease

Kikuchi, K., Saigusa, D., Kanemitsu, Y., Matsumoto, Y., Thanai, P., Suzuki, N., Mise, K., Yamaguchi, H., Nakamura, T., Asaji, K., Mukawa, C., Tsukamoto, H., Sato, T., Oikawa, Y., Iwasaki, T., Oe, Y., Tsukimi, T., Fukuda, N. N., Ho, H. J., Nanto-Hara, F. & 36 others, Ogura, J., Saito, R., Nagao, S., Ohsaki, Y., Shimada, S., Suzuki, T., Toyohara, T., Mishima, E., Shima, H., Akiyama, Y., Akiyama, Y., Ichijo, M., Matsuhashi, T., Matsuo, A., Ogata, Y., Yang, C. C., Suzuki, C., Breeggemann, M. C., Heymann, J., Shimizu, M., Ogawa, S., Takahashi, N., Suzuki, T., Owada, Y., Kure, S., Mano, N., Soga, T., Wada, T., Kopp, J. B., Fukuda, S., Hozawa, A., Yamamoto, M., Ito, S., Wada, J., Tomioka, Y. & Abe, T., 01-12-2019, In : Nature Communications. 10, 1, 1835.

Research output: Contribution to journalArticle

Open Access
kidney diseases
Albuminuria
Diabetic Nephropathies
Sulfates
sulfates
1 Citation (Scopus)

GWAS analysis reveals a significant contribution of PSCA to the risk of Heliobacter pylori-induced gastric atrophy

Hishida, A., Ugai, T., Fujii, R., Nakatochi, M., Wu, M. C., Ito, H., Oze, I., Tajika, M., Niwa, Y., Nishiyama, T., Nakagawa-Senda, H., Suzuki, S., Koyama, T., Matsui, D., Watanabe, Y., Kawaguchi, T., Matsuda, F., Momozawa, Y., Kubo, M., Naito, M. & 2 others, Matsuo, K. & Wakai, K., 04-07-2019, In : Carcinogenesis. 40, 5, p. 661-668 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Pylorus
Atrophy
Prostate
Stomach

GWAS of five gynecologic diseases and cross-trait analysis in Japanese

Masuda, T., Low, S. K., Akiyama, M., Hirata, M., Ueda, Y., Matsuda, K., Kimura, T., Murakami, Y., Kubo, M., Kamatani, Y. & Okada, Y., 01-01-2019, (Accepted/In press) In : European Journal of Human Genetics.

Research output: Contribution to journalArticle

Open Access
Female Genital Diseases
Genome-Wide Association Study
Ovarian Neoplasms
Uterine Neoplasms
Endometriosis

GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation

Terao, C., Momozawa, Y., Ishigaki, K., Kawakami, E., Akiyama, M., Loh, P. R., Genovese, G., Sugishita, H., Ohta, T., Hirata, M., Perry, J. R. B., Matsuda, K., Murakami, Y., Kubo, M. & Kamatani, Y., 01-12-2019, In : Nature Communications. 10, 1, 4719.

Research output: Contribution to journalArticle

Open Access
blood cells
Y Chromosome
Genome-Wide Association Study
chromosomes
Chromosomes
1 Citation (Scopus)

GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture

Matoba, N., Akiyama, M., Ishigaki, K., Kanai, M., Takahashi, A., Momozawa, Y., Ikegawa, S., Ikeda, M., Iwata, N., Hirata, M., Matsuda, K., Kubo, M., Okada, Y. & Kamatani, Y., 01-05-2019, In : Nature Human Behaviour. 3, 5, p. 471-477 7 p.

Research output: Contribution to journalLetter

Genetic Loci
Genome-Wide Association Study
Smoking
Linkage Disequilibrium
Tobacco Products

High-fat and high-cholesterol diet decreases phosphorylated inositol-requiring kinase-1 and inhibits autophagy process in rat liver

Naito, H., Yoshikawa-Bando, Y., Yuan, Y., Hashimoto, S., Kitamori, K., Yatsuya, H. & Nakajima, T., 01-12-2019, In : Scientific reports. 9, 1, 12514.

Research output: Contribution to journalArticle

Open Access
Autophagy
High Fat Diet
Inositol
Phosphotransferases
Cholesterol

High prevalence of equine-like G3P[8] rotavirus in children and adults with acute gastroenteritis in Thailand

Tacharoenmuang, R., Komoto, S., Guntapong, R., Upachai, S., Singchai, P., Ide, T., Fukuda, S., Ruchusatsawast, K., Sriwantana, B., Tatsumi, M., Motomura, K., Takeda, N., Murata, T., Sangkitporn, S., Taniguchi, K. & Yoshikawa, T., 01-01-2019, (Accepted/In press) In : Journal of Medical Virology.

Research output: Contribution to journalArticle

Rotavirus
Gastroenteritis
Thailand
Horses
RNA
1 Citation (Scopus)

Histopathological classification of anti-neutrophil cytoplasmic antibody-associated glomerulonephritis in a nationwide Japanese prospective 2-year follow-up cohort study

For the Research Committee of Intractable Renal Disease and the Research Committee of Intractable Vasculitis Syndrome of the Ministry of Health, Labour, and Welfare of Japan, 15-03-2019, In : Clinical and Experimental Nephrology. 23, 3, p. 387-394 8 p.

Research output: Contribution to journalArticle

Antineutrophil Cytoplasmic Antibodies
Glomerulonephritis
Cohort Studies
Kidney
Glomerular Filtration Rate

HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease

Shimizu, C., Kim, J., Eleftherohorinou, H., Wright, V. J., Hoang, L. T., Tremoulet, A. H., Franco, A., Hibberd, M. L., Takahashi, A., Kubo, M., Ito, K., Tanaka, T., Onouchi, Y., Coin, L. J. M., Levin, M., Burns, J. C. & Shike, H., 01-01-2019, In : Human Immunology.

Research output: Contribution to journalArticle

HLA-C Antigens
Mucocutaneous Lymph Node Syndrome
Amino Acid Substitution
Peptides
Alleles

HLA-DQ and RBFOX1 as susceptibility genes for an outbreak of hydrolyzed wheat allergy

Noguchi, E., Akiyama, M., Yagami, A., Hirota, T., Okada, Y., Kato, Z., Kishikawa, R., Fukutomi, Y., Hide, M., Morita, E., Aihara, M., Hiragun, M., Chinuki, Y., Okabe, T., Ito, A., Adachi, A., Fukunaga, A., Kubota, Y., Aoki, T., Aoki, Y. & 30 others, Nishioka, K., Adachi, T., Kanazawa, N., Miyazawa, H., Sakai, H., Kozuka, T., Kitamura, H., Hashizume, H., Kanegane, C., Masuda, K., Sugiyama, K., Tokuda, R., Furuta, J., Higashimoto, I., Kato, A., Seishima, M., Tajiri, A., Tomura, A., Taniguchi, H., Kojima, H., Tanaka, H., Sakai, A., Morii, W., Nakamura, M., Kamatani, Y., Takahashi, A., Kubo, M., Tamari, M., Saito, H. & Matsunaga, K., 11-2019, In : Journal of Allergy and Clinical Immunology. 144, 5, p. 1354-1363 10 p.

Research output: Contribution to journalArticle

Wheat Hypersensitivity
HLA-DQ Antigens
Disease Outbreaks
Genes
Genome-Wide Association Study

Human herpesvirus-6B infection in pediatric allogenic hematopoietic stem cell transplant patients: Risk factors and encephalitis

Miura, H., Kawamura, Y., Hattori, F., Tanaka, M., Kudo, K., Ihira, M., Yatsuya, H., Takahashi, Y., Kojima, S., Sakaguchi, H., Yoshida, N., Hama, A. & Yoshikawa, T., 01-01-2019, (Accepted/In press) In : Transplant Infectious Disease.

Research output: Contribution to journalArticle

Human Herpesvirus 6
Herpesviridae Infections
Encephalitis
Hematopoietic Stem Cells
Pediatrics

Human serum albumin redox state is associated with decreased renal function in a community-dwelling population

Fujii, R., Ueyama, J., Kanno, T., Suzuki, K., Hamajima, N., Wakai, K., Hasegawa, Y. & Kondo, T., 01-01-2019, In : American journal of physiology. Renal physiology. 316, 1, p. F214-F218

Research output: Contribution to journalArticle

Independent Living
Serum Albumin
Oxidation-Reduction
Kidney
Population
4 Citations (Scopus)

Human tyrosine hydroxylase in Parkinson’s disease and in related disorders

Nagatsu, T., Nakashima, A., Ichinose, H. & Kobayashi, K., 01-04-2019, In : Journal of Neural Transmission. 126, 4, p. 397-409 13 p.

Research output: Contribution to journalReview article

Tyrosine 3-Monooxygenase
Parkinson Disease
Dopaminergic Neurons
Dopamine
Corpus Striatum
2 Citations (Scopus)

Hyoid Bone Movement at Rest by Peripheral Magnetic Stimulation of Suprahyoid Muscles in Normal Individuals

Kagaya, H., Ogawa, M., Mori, S., Aoyagi, Y., Shibata, S., Inamoto, Y., Mori, H. & Saito, E., 01-07-2019, In : Neuromodulation. 22, 5, p. 593-596 4 p.

Research output: Contribution to journalArticle

Hyoid Bone
Muscles
Pain
Fluoroscopy
Deglutition Disorders

Identification by nano-LC-MS/MS of NT5DC2 as a protein binding to tyrosine hydroxylase: Down-regulation of NT5DC2 by siRNA increases catecholamine synthesis in PC12D cells

Nakashima, A., Yamaguchi, H., Kodani, Y., Kaneko, Y. S., Kawata, M., Nagasaki, H., Nagatsu, T. & Ota, A., 03-09-2019, In : Biochemical and Biophysical Research Communications. 516, 4, p. 1060-1065 6 p.

Research output: Contribution to journalArticle

Tyrosine 3-Monooxygenase
Protein Binding
Small Interfering RNA
Catecholamines
Down-Regulation
6 Citations (Scopus)

Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population

Suzuki, K., Akiyama, M., Ishigaki, K., Kanai, M., Hosoe, J., Shojima, N., Hozawa, A., Kadota, A., Kuriki, K., Naito, M., Tanno, K., Ishigaki, Y., Hirata, M., Matsuda, K., Iwata, N., Ikeda, M., Sawada, N., Yamaji, T., Iwasaki, M., Ikegawa, S. & 12 others, Maeda, S., Murakami, Y., Wakai, K., Tsugane, S., Sasaki, M., Yamamoto, M., Okada, Y., Kubo, M., Kamatani, Y., Horikoshi, M., Yamauchi, T. & Kadowaki, T., 01-03-2019, In : Nature Genetics. 51, 3, p. 379-386 8 p.

Research output: Contribution to journalLetter

Genome-Wide Association Study
Gene Frequency
Type 2 Diabetes Mellitus
Population
Acinar Cells
1 Citation (Scopus)

Identification of marker genes and pathways specific to precancerous duodenal adenomas and early stage adenocarcinomas

Sakaguchi, Y., Yamamichi, N., Tomida, S., Takeuchi, C., Kageyama-Yahara, N., Takahashi, Y., Shiogama, K., Inada, K. I., Ichinose, M., Fujishiro, M. & Koike, K., 15-02-2019, In : Journal of Gastroenterology. 54, 2, p. 131-140 10 p.

Research output: Contribution to journalArticle

Adenoma
Adenocarcinoma
Catenins
Genes
Gene Expression

Identification of rare coding variants in TYK2 protective for rheumatoid arthritis in the Japanese population and their effects on cytokine signalling

Motegi, T., Kochi, Y., Matsuda, K., Kubo, M., Yamamoto, K. & Momozawa, Y., 01-01-2019, In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Rheumatoid Arthritis
Genes
Association reactions
Cytokines
Interferons

IgA1 hinge-region clustered glycan fidelity is established early during semi-ordered glycosylation by GalNAc-T2

Stewart, T. J., Takahashi, K., Whitaker, R. H., Raska, M., Placzek, W. J., Novak, J. & Renfrow, M. B., 01-01-2019, In : Glycobiology. 29, 7, p. 543-556 14 p., cwz007.

Research output: Contribution to journalArticle

Glycosylation
Hinges
Immunoglobulin A
Polysaccharides
Site selection
2 Citations (Scopus)

Imaging scoring systems for preoperative molecular diagnoses of lower-grade gliomas

Kanazawa, T., Fujiwara, H., Takahashi, H., Nishiyama, Y., Hirose, Y., Tanaka, S., Yoshida, K. & Sasaki, H., 01-06-2019, In : Neurosurgical Review. 42, 2, p. 433-441 9 p.

Research output: Contribution to journalArticle

Glioma
Methylation
Neoplasms
Mutation
Therapeutics

Impact of fusion for adolescent idiopathic scoliosis on lung volume measured with computed tomography

Fujita, N., Yagi, M., Michikawa, T., Yamada, Y., Suzuki, S., Tsuji, O., Nagoshi, N., Okada, E., Tsuji, T., Nakamura, M., Matsumoto, M. & Watanabe, K., 01-09-2019, In : European Spine Journal. 28, 9, p. 2034-2041 8 p.

Research output: Contribution to journalArticle

Scoliosis
Tomography
Lung
Pneumonectomy
Spinal Fusion

Impact of lumbar hypolordosis on the incidence of symptomatic postoperative spinal epidural hematoma after decompression surgery for lumbar spinal canal stenosis

Fujita, N., Michikawa, T., Yagi, M., Suzuki, S., Tsuji, O., Nagoshi, N., Okada, E., Tsuji, T., Nakamura, M., Matsumoto, M. & Watanabe, K., 25-01-2019, In : European Spine Journal. 28, 1, p. 87-93 7 p.

Research output: Contribution to journalArticle

Spinal Epidural Hematoma
Spinal Stenosis
Spinal Canal
Decompression
Incidence
3 Citations (Scopus)

Impact of serum albumin levels on supratherapeutic PT-INR control and bleeding risk in atrial fibrillation patients on warfarin: A prospective cohort study

Kawai, M., Harada, M., Motoike, Y., Koshikawa, M., Ichikawa, T., Watanabe, E. & Ozaki, Y., 01-03-2019, In : IJC Heart and Vasculature. 22, p. 111-116 6 p.

Research output: Contribution to journalArticle

International Normalized Ratio
Warfarin
Serum Albumin
Atrial Fibrillation
Albumins
2 Citations (Scopus)

Improving TCR affinity on 293T cells

Ohta, R., Demachi-Okamura, A., Akatsuka, Y., Fujiwara, H. & Kuzushima, K., 01-03-2019, In : Journal of Immunological Methods. 466, p. 1-8 8 p.

Research output: Contribution to journalArticle

HEK293 Cells
Peptides
Mutation
HLA-A24 Antigen
Artificial Cells