Find Research Outputs

2019

The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae

Luterbach, C. L., Boshe, A., Henderson, H. I., Cober, E., Richter, S. S., Salata, R. A., Kalayjian, R. C., Watkins, R. R., Hujer, A. M., Hujer, K. M., Rudin, S. D., Domitrovic, T. N., Doi, Y., Kaye, K. S., Evans, S., Fowler, V. G., Bonomo, R. A. & Van Duin, D., 01-01-2019, In : Open Forum Infectious Diseases. 6, 1

Research output: Contribution to journalArticle

Open Access
Carbapenems
Sulfamethoxazole Drug Combination Trimethoprim
Enterobacteriaceae
Enterobacteriaceae Infections
Infection

Time-course analysis of cardiac and serum galectin-3 in viral myocarditis after an encephalomyocarditis virus inoculation

Noguchi, K., Tomita, H., Kanayama, T., Niwa, A., Hatano, Y., Hoshi, M., Sugie, S., Okada, H., Niwa, M. & Hara, A., 01-01-2019, In : PloS one. 14, 1, e0210971.

Research output: Contribution to journalArticle

Encephalomyocarditis virus
Galectin 3
myocarditis
Myocarditis
Viruses

Tolerability of partially and extensively hydrolysed milk formulas in children with cow's milk allergy

Inuo, C., Tanaka, K., Nakajima, Y., Yamawaki, K., Matsubara, T., Iwamoto, H., Tsuge, I., Urisu, A. & Kondo, Y., 01-01-2019, In : Asia Pacific journal of clinical nutrition. 28, 1, p. 49-56 8 p.

Research output: Contribution to journalArticle

Milk Hypersensitivity
Milk
Food
Milk Proteins
Caseins

Transcranial Direct-Current Stimulation Combined with Attention to the Paretic Hand Improves Hand Performance in Stroke Patients: A Double-Blind, Sham-Controlled Study

Moriya, K., Yamaguchi, T., Otaka, Y., Kondo, K. & Tanaka, S., 01-01-2019, Biosystems and Biorobotics. Springer International Publishing, p. 829-833 5 p. (Biosystems and Biorobotics; vol. 21).

Research output: Chapter in Book/Report/Conference proceedingChapter

Transcriptional cofactor Vgll2 is required for functional adaptations of skeletal muscle induced by chronic overload

Honda, M., Tsuchimochi, H., Hitachi, K. & Ohno, S., 01-09-2019, In : Journal of Cellular Physiology. 234, 9, p. 15809-15824 16 p.

Research output: Contribution to journalArticle

Muscle
Skeletal Muscle
Ablation
Metabolism
Muscles
2 Citations (Scopus)

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

Morris, A. P., Le, T. H., Wu, H., Akbarov, A., van der Most, P. J., Hemani, G., Smith, G. D., Mahajan, A., Gaulton, K. J., Nadkarni, G. N., Valladares-Salgado, A., Wacher-Rodarte, N., Mychaleckyj, J. C., Dueker, N. D., Guo, X., Hai, Y., Haessler, J., Kamatani, Y., Stilp, A. M., Zhu, G. & 52 othersCook, J. P., Ärnlöv, J., Blanton, S. H., de Borst, M. H., Bottinger, E. P., Buchanan, T. A., Cechova, S., Charchar, F. J., Chu, P. L., Damman, J., Eales, J., Gharavi, A. G., Giedraitis, V., Heath, A. C., Ipp, E., Kiryluk, K., Kramer, H. J., Kubo, M., Larsson, A., Lindgren, C. M., Lu, Y., Madden, P. A. F., Montgomery, G. W., Papanicolaou, G. J., Raffel, L. J., Sacco, R. L., Sanchez, E., Stark, H., Sundstrom, J., Taylor, K. D., Xiang, A. H., Zivkovic, A., Lind, L., Ingelsson, E., Martin, N. G., Whitfield, J. B., Cai, J., Laurie, C. C., Okada, Y., Matsuda, K., Kooperberg, C., Chen, Y. D. I., Rundek, T., Rich, S. S., Loos, R. J. F., Parra, E. J., Cruz, M., Rotter, J. I., Snieder, H., Tomaszewski, M., Humphreys, B. D. & Franceschini, N., 01-12-2019, In : Nature Communications. 10, 1, 29.

Research output: Contribution to journalArticle

Open Access
kidney diseases
Kidney Diseases
kidneys
Glomerular Filtration Rate
genes
1 Citation (Scopus)

TRPM2 confers susceptibility to social stress but is essential for behavioral flexibility

Andoh, C., Nishitani, N., Hashimoto, E., Nagai, Y., Takao, K., Miyakawa, T., Nakagawa, T., Mori, Y., Nagayasu, K., Shirakawa, H. & Kaneko, S., 01-02-2019, In : Brain Research. 1704, p. 68-77 10 p.

Research output: Contribution to journalArticle

Rotarod Performance Test
Hindlimb Suspension
Muscle Strength
Interpersonal Relations
Oxidation-Reduction
Kynurenine
Drug Discovery
Tryptophan

Two siblings with 11qter deletion syndrome that had been rescued in their mother by uniparental disomy

Kawai, M., Tsutsumi, M., Suzuki, F., Sameshima, K., Dowa, Y., Kyoya, T., Inagaki, H. & Kurahashi, H., 01-03-2019, In : European Journal of Medical Genetics. 62, 3, p. 224-228 5 p.

Research output: Contribution to journalArticle

Jacobsen Distal 11q Deletion Syndrome
Uniparental Disomy
X Chromosome Inactivation
Mosaicism
Cytogenetic Analysis

Upper Limb Motor Function Affects the Outcome after Treatment with Botulinum Toxin A

Fujimura, K., Kagaya, H., Onaka, H., Nagasawa, N., Ishihara, A., Okochi, Y., Yamada, M., Tanikawa, H., Kanada, Y. & Saito, E., 01-01-2019, In : European Neurology. p. 30-36 7 p.

Research output: Contribution to journalArticle

Type A Botulinum Toxins
Upper Extremity
Extremities
Bandages
Therapeutics

Use of a cohorting-unit and systematic surveillance cultures to control a Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae outbreak

Reeme, A. E., Bowler, S. L., Buchan, B. W., Graham, M. B., Behrens, E., Singh, S., Hong, J. C., Arvan, J., Hyke, J. W., Palen, L., Savage, S., Seliger, H., Huerta, S., Ledeboer, N. A., Kotay, S., Mathers, A. J., Cooper, V. S., Mustapha, M. M., Mettus, R. T., Doi, Y. & 1 othersMunoz-Price, L. S., 01-01-2019, In : Infection Control and Hospital Epidemiology. p. 1-7 7 p.

Research output: Contribution to journalArticle

Klebsiella pneumoniae
Enterobacteriaceae
Disease Outbreaks
Infection Control
carbapenemase
1 Citation (Scopus)

Utility of the Serum Cystatin C level for diagnosis of osteoporosis among middle-aged and elderly people

Tanaka, S., Ando, K., Kobayashi, K., Hida, T., Ito, K., Tsushima, M., Morozumi, M., Machino, M., Ota, K., Suzuki, K., Seki, T., Ishiguro, N., Hasegawa, Y. & Imagama, S., 01-01-2019, In : BioMed Research International. 2019, 5046852.

Research output: Contribution to journalArticle

Cystatin C
Osteoporosis
Serum
Bone
Creatinine

Validation of the japanese version of the yale food addiction scale 2.0 (J-YFAS 2.0)

Khine, M. T., Ota, A., Gearhardt, A. N., Fujisawa, A., Morita, M., Minagawa, A., Li, Y., Naito, H. & Yatsuya, H., 01-03-2019, In : Nutrients. 11, 3, 687.

Research output: Contribution to journalArticle

Open Access
signs and symptoms (animals and humans)
ingestion
Food
distress
college students

Vangl2 interaction plays a role in the proteasomal degradation of Prickle2

Nagaoka, T., Furuse, M., Ohtsuka, T., Tsuchida, K. & Kishi, M., 01-12-2019, In : Scientific Reports. 9, 1, 2912.

Research output: Contribution to journalArticle

Open Access
Cell Polarity
Proteins
LIM Domain Proteins
Proteasome Inhibitors
Ubiquitin-Protein Ligases
1 Citation (Scopus)

Warm ischemic time as a critical risk factor of graft failure from donors after cardiac death: A single-center experience over three decades in the Kidney Donor Profile Index/Kidney Donor Risk Index era in Japan

Kusaka, M., Kubota, Y., Takahashi, H., Sasaki, H., Kawai, A., Takenaka, M., Fukami, N., Kenmochi, T., Shiroki, R. & Hoshinaga, K., 01-02-2019, In : International Journal of Urology. 26, 2, p. 247-252 6 p.

Research output: Contribution to journalArticle

Warm Ischemia
Japan
Transplants
Kidney
Graft Survival

Wavelet p-Leader Non Gaussian Multiscale Expansions for Heart Rate Variability Analysis in Congestive Heart Failure Patients

Wendt, H., Abry, P., Kiyono, K., Hayano, J., Watanabe, E. & Yamamoto, Y., 01-01-2019, In : IEEE Transactions on Biomedical Engineering. 66, 1, p. 80-88 9 p., 8336968.

Research output: Contribution to journalArticle

Fractals

Working hours and risk of acute myocardial infarction and stroke among middle-aged japanese men: The Japan public health center-based prospective study cohort II

for the Japan Public Health Center-Based (JPHC) Prospective Study Group, 01-01-2019, In : Circulation Journal. 83, 5, p. 1072-1079 8 p.

Research output: Contribution to journalArticle

Open Access
Japan
Public Health
Stroke
Myocardial Infarction
Prospective Studies
2018

A 20-year prospective longitudinal MRI study on cervical spine after whiplash injury: Follow-up of a cross-sectional study

Daimon, K., Fujiwara, H., Nishiwaki, Y., Okada, E., Nojiri, K., Shimizu, K., Ishihama, H., Fujita, N., Ichihara, D., Tsuji, T., Nakamura, M., Matsumoto, M. & Watanabe, K., 01-01-2018, (Accepted/In press) In : Journal of Orthopaedic Science.

Research output: Contribution to journalArticle

Whiplash Injuries
Longitudinal Studies
Spine
Neck Pain
Cross-Sectional Studies
2 Citations (Scopus)

A 20-year prospective longitudinal study of degeneration of the cervical spine in a volunteer cohort assessed using MRI follow-up of a cross-sectional study

Daimon, K., Fujiwara, H., Nishiwaki, Y., Okada, E., Nojiri, K., Watanabe, M., Katoh, H., Shimizu, K., Ishihama, H., Fujita, N., Tsuji, T., Nakamura, M., Matsumoto, M. & Watanabe, K., 01-01-2018, In : Journal of Bone and Joint Surgery - American Volume. 100, 10, p. 843-849 7 p.

Research output: Contribution to journalArticle

Longitudinal Studies
Volunteers
Spine
Cross-Sectional Studies
Magnetic Resonance Imaging

A basic study on self-reconstitution of alveolar epithelium-like cells by tissue stem cells in mouse lung

Hayashi, M., Yamamoto, N., Hiramatsu, N., Isogai, S., Gotoh, Y., Goto, Y., Kondo, M. & Imaizumi, K., 01-10-2018, In : In Vitro Cellular and Developmental Biology - Animal. 54, 9, p. 648-657 10 p.

Research output: Contribution to journalArticle

Stem Cells
Epithelium
Organoids
Lung
Vacuoles

Absence of fosfomycin resistance in gastrointestinal Escherichia coli following fosfomycin therapy

Mettus, R. T., Bowler, S. L., Kantz, S. F., McElheny, C. L., Pasculle, A. W. & Doi, Y., 01-09-2018, In : Journal of Global Antimicrobial Resistance. 14, p. 109-110 2 p.

Research output: Contribution to journalLetter

Fosfomycin
Escherichia coli
Therapeutics
1 Citation (Scopus)

A Case of Non-24-Hour Sleep-Wake Rhythm Disorder Treated With a Low Dose of Ramelteon and Behavioral Education

Watanabe, A., Hirose, M., Arakawa, C., Iwata, N. & Kitajima, T., 15-07-2018, In : Journal of Clinical Sleep Medicine. 14, 7, p. 1265-1267 3 p.

Research output: Contribution to journalArticle

Circadian Rhythm Sleep Disorders
Education
Actigraphy
Photoperiod
Sleep

A case of uterine lymphangioleiomyomatosis in a young woman that was identified via peritonitis

Yoshizawa, H., Kawai, S., Hirota, Y., Ueda, T., Kuroda, M. & Fujii, T., 01-01-2018, (Accepted/In press) In : Journal of Obstetrics and Gynaecology Research.

Research output: Contribution to journalArticle

Lymphangioleiomyomatosis
Peritonitis
Tuberous Sclerosis
Ovariectomy
Hysterectomy

A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework

Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, 25-06-2018, In : BMC Genomics. 19, 1, 494.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Inservice Training
Dementia
Atmosphere
Japan
Learning
1 Citation (Scopus)

Adsorptive filtration systems for effective removal of blood amyloid β: a potential therapy for Alzheimer’s disease

Kitaguchi, N., Kawaguchi, K., Yamazaki, K., Kawachi, H., Sakata, M., Kaneko, M., Kato, M., Sakai, K., Ohashi, N., Hasegawa, M., Hiki, Y. & Yuzawa, Y., 01-06-2018, In : Journal of Artificial Organs. 21, 2, p. 220-229 10 p.

Research output: Contribution to journalArticle

Amyloid
Alzheimer Disease
Blood
Brain
Adsorption
2 Citations (Scopus)

Age at first birth in women is genetically associated with increased risk of schizophrenia

Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 othersBacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Del Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Haan, L. D., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Juliá, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Keong, J. L. C., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'callaghan, E., O'dushlaine, C., O'neill, F. A., Oh, S. Y., Olincy, A., Olsen, L., Os, J. V., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Stroup, T. S., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Cichon, S., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Rietschel, M., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, T., Daly, M. J., Sullivan, P. F. & O'donovan, M. C., 01-12-2018, In : Scientific Reports. 8, 1, 10168.

Research output: Contribution to journalArticle

Birth Order
Schizophrenia
Parents
Mental Health
Genetic Heterogeneity

A genome-wide association study identifies three novel genetic markers for response to tamoxifen: A prospective multicenter study

Onishi, H., Udagawa, C., Kubo, M., Nakamura, S., Akashi-Tanaka, S., Kuwayama, T., Watanabe, C., Takamaru, T., Takei, H., Ishikawa, T., Miyahara, K., Matsumoto, H., Hasegawa, Y., Momozawa, Y., Low, S. K., Kutomi, G., Shima, H., Satomi, F., Okazaki, M., Zaha, H. & 14 othersOnomura, M., Matsukata, A., Sagara, Y., Baba, S., Yamada, A., Shimada, K., Shimizu, D., Tsugawa, K., Shimo, A., Hartman, M., Chan, C. W., Lee, S. C., Endo, I. & Zembutsu, H., 01-08-2018, In : PloS one. 13, 8, e0201606.

Research output: Contribution to journalArticle

Open Access
tamoxifen
Genome-Wide Association Study
Tamoxifen
prospective studies
Genetic Markers
20 Citations (Scopus)

A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder

Advanced Collaborative Study of Mood Disorder (COSMO) team, 01-03-2018, In : Molecular Psychiatry. 23, 3, p. 639-647 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Population
Psychiatry
Regulator Genes
2 Citations (Scopus)

A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study

Nakagawa-Senda, H., Hachiya, T., Shimizu, A., Hosono, S., Oze, I., Watanabe, M., Matsuo, K., Ito, H., Hara, M., Nishida, Y., Endoh, K., Kuriki, K., Katsuura-Kamano, S., Arisawa, K., Nindita, Y., Ibusuki, R., Suzuki, S., Hosono, A., Mikami, H., Nakamura, Y. & 16 othersTakashima, N., Nakamura, Y., Kuriyama, N., Ozaki, E., Furusyo, N., Ikezaki, H., Nakatochi, M., Sasakabe, T., Kawai, S., Okada, R., Hishida, A., Naito, M., Wakai, K., Momozawa, Y., Kubo, M. & Tanaka, H., 01-12-2018, In : Scientific Reports. 8, 1, 1493.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Coffee
Japan
Cohort Studies
Population
11 Citations (Scopus)

A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes

Van Zuydam, N. R., Ahlqvist, E., Sandholm, N., Deshmukh, H., William Rayner, N., Abdalla, M., Ladenvall, C., Ziemek, D., Fauman, E., Robertson, N. R., McKeigue, P. M., Valo, E., Forsblom, C., Harjutsalo, V., Perna, A., Rurali, E., Loredana Marcovecchio, M., Igo, R. P., Salem, R. M., Perico, N. & 578 othersLajer, M., Käräjämäki, A., Imamura, M., Kubo, M., Takahashi, A., Sim, X., Liu, J., Van Dam, R. M., Jiang, G., Tam, C. H. T., Luk, A. O. Y., Lee, H. M., Lim, C. K. P., Szeto, C. C., So, W. Y., Chan, J. C. N., Ang, S. F., Dorajoo, R., Wang, L., Clara, T. S. H., McKnight, A. J., Duffy, S., Warren, Pezzolesi, M. G., Marre, M., Gyorgy, B., Hadjadj, S., Hiraki, L. T., Ahluwalia, T. S., Almgren, P., Schulz, C. A., Orho-Melander, M., Linneberg, A., Christensen, C., Witte, D. R., Grarup, N., Brandslund, I., Melander, O., Paterson, A. D., Tregouet, D., Maxwell, A. P., Lim, S. C., Ma, R. C. W., Shyong Tai, E., Maeda, S., Lyssenko, V., Tuomi, T., Krolewski, A. S., Rich, S. S., Hirschhorn, J. N., Florez, J. C., Dunger, D., Pedersen, O., Hansen, T., Rossing, P., Remuzzi, G., Brosnan, M. J., Palmer, C. N. A., Groop, P. H., Colhoun, H. M., Groop, L. C., McCarthy, M. I., Koivula, S., Uggeldahl, T., Forslund, T., Halonen, A., Koistinen, A., Koskiaho, P., Laukkanen, M., Saltevo, J., Tiihonen, M., Forsen, M., Granlund, H., Jonsson, A. C., Nyroos, B., Kinnunen, P., Orvola, A., Salonen, T., Vähänen, A., Paldanius, K. R., Riihelä, M., Ryysy, L., Laukkanen, K. H., Nyländen, P., Sademies, A., Anderson, S., Asplund, B., Byskata, U., Liedes, P., Kuusela, M., Virkkala, T., Nikkola, A., Ritola, E., Niska, T. M., Saarinen, H., Oukko-Ruponen, S. E., Virtanen, T., Lyytinen, V. A., Kari, P. H., Simonen, T., Kaprio, S. A., Kärkkäinen, J., Rantaeskola, B., Kääriäinen, T. P., Haaga, J., Pietiläinen, A. L., Klemetti, S., Nyandoto, T., Rontu, E., Satuli-Autere, S., Toivonen, K. R., Lansimaki, H. V., Ahonen, R., Ivaska-Suomela, M., Jauhiainen, A., Laine, M. M., Pellonpää, T., Puranen, R., Airas, M. A., Laakso, J., Rautavaara, K., Erola, R. M., Jatkola, E., Lönnblad, T. R., Malm, A., Mäkelä, J., Rautamo, E., Hentunen, P., Lagerstam, J., Feodoroff, M., Gordin, D., Heikkilä, O., Hietala, K., Fagerudd, J., Korolainen, M., Kyllönen, L., Kytö, J., Lindh, S., Pettersson-Fernholm, K., Rosengård-Bärlund, M., Sandelin, A., Thorn, L., Tuomikangas, J., Vesisenaho, T., Wadén, J., Sipilä, V., Kalliomäki, F. T., Koskelainen, J., Nikkanen, R., Savolainen, N., Sulonen, H., Valtonen, E., Norvio, L., Hämäläinen, A., Toivanen, E., Parta, J. A., Pirttiniemi, I., Aranko, S., Ervasti, S., Kauppinen-Mäkelin, R., Kuusisto, A., Leppälä, T., Nikkilä, K., Pekkonen, L., Jokelainen, K. S., Kananen, K., Karjalainen, M., Kemppainen, P., Mankinen, A. M., Reponen, A., Sankari, M., Suominen, P., Lappalainen, A., Liimatainen, M., Santaholma, J., Aimolahti, A., Huovinen, E., Ilkka, V., Lehtimäki, M., Pälikkö-Kontinen, E., Vanhanen, A., Koskinen, E., Siitonen, T., Huttunen, E., Ikäheimo, R., Karhapää, P., Kekäläinen, P., Laakso, M., Lakka, T., Lampainen, E., Moilanen, L., Tanskanen, S., Niskanen, L., Tuovinen, U., Vauhkonen, I., Voutilainen, E., Huang, Y., Lan, H. Y., Lok, S., Tomlinson, B., Tsui, S. K. W., Yu, W., Yip, K. Y. L., Chan, T. F., Fan, X., Tang, N., Tian, X., Chan, K. K. H., Xie, F., Ng, A. C. W., Cheung, G. P. Y., Yeung, M. W., Mai, S., Xie, F., Zhang, S., Yu, P., Weng, M., Savage, D. A., Walker, J., Thomas, S., Viberti, G. C., Boulton, A. J. M., Marshall, S., Demaine, A. G., Millward, B. A., Bain, S. C., Mäkinen, V. P., Ahola, A. J., Dahlström, E., Gordin, D., Heikkilä, O., Hietala, K., Kytö, J., Lehto, M., Lithovius, R., Panduru, N. M., Parkkonen, M., Rosengård-Bärlund, M., Saraheimo, M., Söderlund, J., Soro-Paavonen, A., Syreeni, A., Thorn, L. M., Tolonen, N., Wadén, J., McKay, G. J., Isakova, T., Guiducci, C., Taylor, A., Mirel, D. B., Williams, W. W., Brennan, E. P., Sadlier, D. M., Martin, F., Godson, C., Mayer, L., Gubitosi-Klug, R., Bourne, P., Schutta, M., Lackaye, M. E., Gregory, N. S., Kruger, D., Jones, J. K., Bhan, A., Golden, E., Aiello, L., Larkin, M., Nathan, D., Ziegler, G., Caulder, S., Pittman, C., Luttrell, L., Lopes-Virella, M., Johnson, M., Gunyou, K., Bergenstal, R., Vittetoe, B., Sivitz, W., Flaherty, N., Bantle, J., Hitt, S., Goldstein, D., Hainsworth, D., Cimino, L., Orchard, T., Wigley, C., Dagogo-Jack, S., Strowig, S., Raskin, P., Barnie, A., Zinman, B., Fahlstrom, R., Palmer, J., Harth, J., Driscoll, M., McDonald, C., Lipps Hagan, J., May, M., Levandoski, L., White, N., Gatcomb, P., Tamborlane, W., Adelman, D., Colson, S., Molitch, M., Lorenzi, G., Mudaliar, S., Johnsonbaugh, S., Miller, R., Canady, J., Schade, D., Bernal, M. L., Malone, J., Morrison, A., Martin, C., Herman, W., Pop-Busui, R., Cowie, C., Leschek, E., Cleary, P., Lachin, J., Zinman, B., Lorenzi, G., Braffett, B., Steffes, M., Arends, V., Blodi, B., Danis, R., Lawrence, D., Wabers, H., Soliman, E., Zhang, Z. M., Campbell, C., Hensley, S., Keasler, L., Mark, M., Albertini, M., Boustany, C., Ehlgen, A., Gerl, M., Huber, J., Schölch, C., Zimdahl-Gelling, H., Agardh, E., Ajanki, T., Al Maghrabi, N., Apelqvist, J., Bengtsson, E., Berglund, L., Björckbacka, H., Blom-Nilsson, U., Borell, M., Burström, A., Cilio, C., Cinthio, M., Dreja, K., Dunér, P., Engelbertsen, D., Fadista, J., Gomez, M., Goncalves, I., Hedblad, B., Hultgårdh, A., Johansson, M. E., Kennbäck, C., Kravic, J., Lernmark, A., Lindholm, E., Ling, C., Luthman, H., Neptin, M., Nilsson, J., Nilsson, P., Nilsson, T., Nordin, G., Ottoson-Laakso, E., Persson, A., Persson, M., Persson, M. A., Postma, J., Pranter, E., Rattik, S., Sterner, G., Tindberg, L., Wigren, M., Zetterqvist, A., Åkerlund, M., Ostling, G., Kanninen, T., Ahonen-Bishopp, A., Eliasson, A., Herrala, T., Tikka-Kleemola, P., Hamsten, A., Betsholtz, C., Björkholm, A., Foroogh, F., Genové, G., Gertow, K., Gigante, B., He, B., Leander, K., McLeod, O., Nastase-Mannila, M., Patrakka, J., Silveira, A., Strawbridge, R., Tryggvason, K., Vikström, M., Ohrvik, J., Österholm, A. M., Thorand, B., Gieger, C., Grallert, H., Ludwig, T., Nitz, B., Schneider, A., Wang-Sattler, R., Zierer, A., Benigni, A., Donadelli, R., Lesti, M. D., Noris, M., Piras, R., Ruggenenti, P., Chassin, L., Dalton, N., Deanfield, J., Horsford, J., Rice, C., Rudd, J., Walker, N., Whitehead, K., Wong, M., Adams, F., Akbar, T., Belch, J., Dove, F., Ellingford, A., Farran, B., Ferguson, M., Henderson, G., Houston, G., Khan, F., Leese, G., Livingstone, S., Looker, H., McCann, M., McGurnaghan, S., Morris, A., Newton, D., Pearson, E., Reekie, G., Smith, N., Shore, A., Aizawa, K., Ball, C., Bellenger, N., Casanova, F., Frayling, T., Gates, P., Gooding, K., Hattersley, A., Ling, R., Mawson, D., Shandas, R., Strain, D., Thorn, C., Smith, U., Hammarstedt, A., Häring, H., Sesti, G., Fagerholm, E., Parkkonen, M., Tolonen, N., Toppila, I., Salomaa, V., Havulinna, A., Kristiansson, K., Okamo, P., Peltola, T., Perola, M., Pietilä, A., Ripatti, S., Taimi, M., Ylä-Herttuala, S., Babu, M., Dijkstra, M., Gurzeler, E., Huusko, J., Kholová, I., Laakso, M., Merentie, M., Poikolainen, M., Groves, C., Juliusdottir, T., Karpe, F., Lagou, V., Morris, A., Cobelli, C., Di Camillo, B., Finotello, F., Sambo, F., Toffolo, G., Trifoglio, E., Bellazzi, R., Barbarini, N., Bucalo, M., Larizza, C., Magni, P., Malovini, A., Marini, S., Mulas, F., Quaglini, S., Sacchi, L., Vitali, F., Ferrannini, E., Boldrini, B., Kozakova, M., Mari, A., Morizzo, C., Mota, L., Natali, A., Palombo, C., Venturi, E., Walker, M., Patrono, C., Pagliaccia, F., Rocca, B., Nuutila, P., Haukkala, J., Knuuti, J., Roivainen, A., Saraste, A., McKeague, P., Colombo, M., Steckel-Hamann, B., Bokvist, K., Shankar, S., Thomas, M., Gan, L. M., Heinonen, S., Jönsson-Rylander, A. C., Momo, R., Schnecke, V., Unwin, R., Walentinsson, A., Whatling, C., Nogoceke, E., Pacheco, G. D., Formentini, I., Schindler, T., Tortoli, P., Bassi, L., Boni, E., Dallai, A., Guidi, F., Lenge, M., Matera, R., Ramalli, A., Ricci, S., Viti, J., Jablonka, B., Crowther, D., Gassenhuber, J., Hess, S., Hubschle, T., Juretschke, H. P., Rutten, H., Sadowski, T., Wohlfart, P., Clerin, V., Hyde, C., Malarstig, A., Pullen, N., Tilley, M., Tuthill, T. & Vangjeli, C., 01-07-2018, In : Diabetes. 67, 7, p. 1414-1427 14 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Diabetic Nephropathies
Type 2 Diabetes Mellitus
Phenotype
Glomerular Filtration Rate
4 Citations (Scopus)

Age-related declines in the ability to modulate common input to bilateral and unilateral plantar flexors during forward postural lean

Watanabe, T., Saito, K., Ishida, K., Tanabe, S. & Nojima, I., 25-06-2018, In : Frontiers in Human Neuroscience. 12, 254.

Research output: Contribution to journalArticle

Skeletal Muscle
Young Adult
Muscles
Electromyography
Foot
2 Citations (Scopus)

A high level of blood urea nitrogen is a significant predictor for in-hospital mortality in patients with acute myocardial infarction

J-MINUET investigators, 01-01-2018, In : International heart journal. 59, 2, p. 263-271 9 p.

Research output: Contribution to journalArticle

Blood Urea Nitrogen
Hospital Mortality
Myocardial Infarction
Odds Ratio
Confidence Intervals

A hypoglycemia-inducing giant borderline phyllodes tumor secreting high-molecular-weight insulin-like growth factor II: Immunohistochemistry and a western blot analysis

Hikichi, M., Kiriyama, Y., Hayashi, T., Ushimado, K., Kobayashi, N., Urano, M., Kuroda, M. & Utsumi, T., 01-01-2018, In : Internal Medicine. 57, 2, p. 237-241 5 p.

Research output: Contribution to journalArticle

Phyllodes Tumor
Insulin-Like Growth Factor II
Hypoglycemia
Molecular Weight
Western Blotting
7 Citations (Scopus)

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

The CHARGE Neurology Working Group, The COGENT-Kidney Consortium, The GIANT Consortium & Lifelines Cohort Study, 01-03-2018, In : American Journal of Human Genetics. 102, 3, p. 375-400 26 p.

Research output: Contribution to journalArticle

Smoking
Genome
Blood Pressure
Genome-Wide Association Study
Blood Vessels
2 Citations (Scopus)

A lower eicosapentaenoic acid/arachidonic acid ratio is associated with in-hospital fatal arrhythmic events in patients with acute myocardial infarction: a J-MINUET substudy

on behalf of J-MINUET Investigators, 01-05-2018, In : Heart and Vessels. 33, 5, p. 481-488 8 p.

Research output: Contribution to journalArticle

Eicosapentaenoic Acid
Arachidonic Acid
Myocardial Infarction
Ventricular Fibrillation
Ventricular Tachycardia

Amino acid position 37 of HLA-DRβ1 affects susceptibility to Crohn's disease in Asians

Han, B., Akiyama, M., Kim, K. K., Oh, H., Choi, H., Lee, C. H., Jung, S., Lee, H. S., Kim, E. E., Cook, S., Haritunians, T., Yamazaki, K., Park, S. H., Ye, B. D., McGovern, D. P. B., Esaki, M., Kawaguchi, T., Khor, S. S., Taylor, K. D., Rotter, J. I. & 12 othersSuzuki, Y., Matsui, T., Motoya, S., Bang, S. Y., Kim, T. H., Momozawa, Y., Kamatani, Y., Tokunaga, K., Kubo, M., Okada, Y., Yang, S. K. & Song, K., 01-11-2018, In : Human molecular genetics. 27, 22, p. 3901-3910 10 p.

Research output: Contribution to journalArticle

HLA Antigens
Crohn Disease
Amino Acids
Ulcerative Colitis
Inflammatory Bowel Diseases

A multicenter prospective cohort study to develop frailty-based prognostic criteria in heart failure patients (FLAGSHIP): Rationale and design

on behalf of the FLAGSHIP collaborators, 02-08-2018, In : BMC Cardiovascular Disorders. 18, 1, 159.

Research output: Contribution to journalArticle

Cohort Studies
Heart Failure
Prospective Studies
Practice Guidelines
Mortality
2 Citations (Scopus)

A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis

Japan Scoliosis Clinical Research Group (JSCRG) & Texas Scottish Rite Hospital for Children Clinical Group (TSRHCCG), 01-12-2018, In : Scientific Reports. 8, 1, 11575.

Research output: Contribution to journalArticle

Open Access
Scoliosis
Meta-Analysis
Genome-Wide Association Study
Far East
Computer Simulation

Analysis of variability of R-R intervals for the diagnosis of atrial fibrillation: A new algorithm

Matsui, T., Shinozaki, R., Watanabe, E. & Aizawa, Y., 01-05-2018, In : Journal of Electrocardiology. 51, 3, p. 382-385 4 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Sensitivity and Specificity
14 Citations (Scopus)

Anamorelin (ONO-7643) for the treatment of patients with non–small cell lung cancer and cachexia: Results from a randomized, double-blind, placebo-controlled, multicenter study of Japanese patients (ONO-7643-04)

Katakami, N., Uchino, J., Yokoyama, T., Naito, T., Kondo, M., Yamada, K., Kitajima, H., Yoshimori, K., Sato, K., Saito, H., Aoe, K., Tsuji, T., Takiguchi, Y., Takayama, K., Komura, N., Takiguchi, T. & Eguchi, K., 01-02-2018, In : Cancer. 124, 3, p. 606-616 11 p.

Research output: Contribution to journalArticle

Cachexia
Non-Small Cell Lung Carcinoma
Multicenter Studies
Placebos
Anorexia

A novel design of rat's head positioner for MRI and its feasibility

Narita, H. & Yamada, M., 01-01-2018, In : Journal of Advanced Mechanical Design, Systems and Manufacturing. 12, 6, 116.

Research output: Contribution to journalArticle

Magnetic resonance imaging
Rats
Brain
Animals
3D printers
2 Citations (Scopus)

A novel IFIH1 mutation in the pincer domain underlies the clinical features of both Aicardi–Goutières and Singleton–Merten syndromes in a single patient

Takeichi, T., Katayama, C., Tanaka, T., Okuno, Y., Murakami, N., Kono, M., Sugiura, K., Aoyama, Y. & Akiyama, M., 01-02-2018, In : British Journal of Dermatology. 178, 2, p. e111-e113

Research output: Contribution to journalLetter

Mutation
Singleton Merten syndrome
1 Citation (Scopus)

Anti-dementia drugs for psychopathology and cognitive impairment in schizophrenia: A systematic review and meta-analysis

Kishi, T., Ikuta, T., Oya, K., Matsunaga, S., Matsuda, Y. & Iwata, N., 01-01-2018, In : International Journal of Neuropsychopharmacology. 21, 8, p. 748-757 10 p.

Research output: Contribution to journalReview article

Psychopathology
Antipsychotic Agents
Dementia
Meta-Analysis
Schizophrenia

Anti-GM1 ganglioside antibodies modulate membrane-associated sphingomyelin metabolism by altering neutral sphingomyelinase activity

Ueda, A., Shima, S., Murate, K., Kikuchi, K., Nagao, R., Maeda, T., Muto, E., Niimi, Y., Mizutani, Y. & Mutoh, T., 01-06-2018, In : Molecular and Cellular Neuroscience. 89, p. 42-48 7 p.

Research output: Contribution to journalArticle

G(M1) Ganglioside
Sphingomyelin Phosphodiesterase
Sphingomyelins
Membranes
Antibodies
2 Citations (Scopus)

Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination

Akahori, Y., Wang, L., Yoneyama, M., Seo, N., Okumura, S., Miyahara, Y., Amaishi, Y., Okamoto, S., Mineno, J., Ikeda, H., Maki, T., Fujiwara, H., Akatsuka, Y., Kato, T. & Shiku, H., 13-09-2018, In : Blood. 132, 11, p. 1134-1145 12 p.

Research output: Contribution to journalArticle

Wilms Tumor
Oncogene Proteins
T-Cell Antigen Receptor
Tumors
Vaccination

Aortic stenosis is a risk factor for all-cause mortality in patients on dialysis: A multicenter prospective cohort analysis

Inaguma, D., Sasakawa, Y., Suzuki, N., Ito, E., Takahashi, K., Hayashi, H., Koide, S., Hasegawa, M., Yuzawa, Y., Tamai, H., Tsutsui, S., Ueda, T., Narita, Y., Sofue, F., Hirano, Y., Motokawa, M., Miwa, M., Suzuki, N., Kojima, S., Takatsu, H. & 60 othersAkahori, T., Murakami, K., Shimano, Y., Miyazaki, T., Baba, K., Iida, Y., Endo, H., Furuya, R., Aoyama, I., Mizutani, Y., Seno, H., Nagaya, T., Kasuga, H., Sugiyama, S., Kojima, K., Fujisawa, K., Naruse, T., Ishida, O., Oishi, H., Ono, A., Shimizu, H., Kato, K., Ito, I., Yasutomi, S., Yamazaki, C., Yasuda, K., Matsuoka, T., Tsuruta, Y., Mizuno, M., Ono, M., Okada, M., Tanoue, A., Obayashi, T., Yokoyama, I., Kushimoto, H., Hasegawa, H., Kawasumi, M., Nomura, A., Sakurauchi, Y., Yamashita, M., Asada, H., Ohara, K., Koyabu, S., Tada, M., Sato, F., Yamaguchi, S., Ogawa, H., Ota, Y., Matsumoto, Y., Otsuka, S., Namii, Y., Kasai, Y., Kato, N., Nakayama, M., Sato, H., Inaba, S., Shibata, M., Yamashita, H., Yamamoto, J. & Yamaguchi, M., 03-04-2018, In : BMC Nephrology. 19, 1, 80.

Research output: Contribution to journalArticle

Aortic Valve Stenosis
Dialysis
Cohort Studies
Mortality
Aortic Valve
1 Citation (Scopus)

A panel of microRNA signature as a tool for predicting survival of patients with urothelial carcinoma of the bladder

Inamoto, T., Uehara, H., Akao, Y., Ibuki, N., Komura, K., Takahara, K., Takai, T., Uchimoto, T., Saito, K., Tanda, N., Yoshikawa, Y., Minami, K., Hirano, H., Nomi, H., Kato, R., Hayashi, T. & Azuma, H., 01-01-2018, In : Disease Markers. 2018, 5468672.

Research output: Contribution to journalArticle

MicroRNAs
Urinary Bladder
Carcinoma
Survival
Phenotype

A phase II trial of Ifosfamide combination with recommended supportive therapy for recurrent SCLC in second-line and heavily treated setting

Tanaka, I., Kawada, K., Morise, M., Hase, T., Hayashi, H., Sokai, A., Fukatsu, A., Kondo, M., Nomura, F. & Hasegawa, Y., 01-02-2018, In : Cancer Chemotherapy and Pharmacology. 81, 2, p. 339-345 7 p.

Research output: Contribution to journalArticle

Ifosfamide
Small Cell Lung Carcinoma
Refractory materials
Toxicity
Cells

Aphasia Following Left Putaminal Hemorrhage at a Rehabilitation Hospital

Maeshima, S., Okamoto, S., Okazaki, H., Funahashi, R., Hiraoka, S., Hori, H., Yagihashi, K., Fuse, I., Tanaka, S., Asano, N. & Sonoda, S., 01-03-2018, In : European Neurology. 79, 1-2, p. 33-37 5 p.

Research output: Contribution to journalArticle

Putaminal Hemorrhage
Aphasia
Hematoma
Rehabilitation
Wernicke Aphasia