Find Research Outputs

2019

Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas

Kataoka, K., Miyoshi, H., Sakata, S., Dobashi, A., Couronné, L., Kogure, Y., Sato, Y., Nishida, K., Gion, Y., Shiraishi, Y., Tanaka, H., Chiba, K., Watatani, Y., Kakiuchi, N., Shiozawa, Y., Yoshizato, T., Yoshida, K., Makishima, H., Sanada, M., Onozawa, M. & 18 others, Teshima, T., Yoshiki, Y., Ishida, T., Suzuki, K., Shimada, K., Tomita, A., Kato, M., Ota, Y., Izutsu, K., Demachi-Okamura, A., Akatsuka, Y., Miyano, S., Yoshino, T., Gaulard, P., Hermine, O., Takeuchi, K., Ohshima, K. & Ogawa, S., 01-07-2019, In : Leukemia. 33, 7, p. 1687-1699 13 p.

Research output: Contribution to journal › Article

Open Access

Human Herpesvirus 4

Lymphoma

Ligands

Extranodal NK-T-Cell Lymphoma

Large Granular Lymphocytic Leukemia

Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population

Sakaue, S., Akiyama, M., Hirata, M., Matsuda, K., Murakami, Y., Kubo, M., Kamatani, Y. & Okada, Y., 01-01-2019, (Accepted/In press) In : European Journal of Human Genetics.

Research output: Contribution to journal › Article

Open Access

Alleles

Genotype

Mortality

Population

Survival Analysis

Gastric Mucosal Microarchitectures Associated with Irreversibility with Helicobacter pylori Eradication and Downregulation of Micro RNA (miR)-124a

Tahara, T., Tahara, S., Horiguchi, N., Kawamura, T., Okubo, M., Nagasaka, M., Nakagawa, Y., Shibata, T., Urano, M., Tsukamoto, T., Kuroda, M. & Ohmiya, N., 21-10-2019, In : Cancer Investigation. 37, 9, p. 417-426 10 p.

Research output: Contribution to journal › Article

MicroRNAs

Helicobacter pylori

Stomach

Down-Regulation

Narrow Band Imaging

1 Citation (Scopus)

Gastrointestinal bleeding with severe mucosal involvement in a patient with generalized pustular psoriasis without IL36RN mutation

Komatsuda, S., Kamata, M., Chijiwa, C., Namiki, K., Fukaya, S., Hayashi, K., Fukuyasu, A., Tanaka, T., Ishikawa, T., Ohnishi, T., Abe, K., Yamamoto, T., Aozasa, N., Sugiura, K. & Tada, Y., 01-01-2019, In : Journal of Dermatology. 46, 1, p. 73-75 3 p.

Research output: Contribution to journal › Article

Psoriasis

Hemorrhage

Mutation

Erythema

Tongue

8 Citations (Scopus)

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

CommonMind Consortium, The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium & iPSYCH-GEMS Schizophrenia Working Group, 01-04-2019, In : Nature Genetics. 51, 4, p. 659-674 16 p.

Research output: Contribution to journal › Article

Genome-Wide Association Study

Prefrontal Cortex

Schizophrenia

Tay-Sachs Disease

Gene Expression

Generalized pustular psoriasis from heterozygous IL36RN mutation developed after liver surgery

Fukushima, H., Iwata, Y., Numata, S., Saito, K., Watanabe, S., Kobayashi, T. & Sugiura, K., 01-01-2019, In : Journal of Dermatology. 46, 8, p. e301-e302

Research output: Contribution to journal › Letter

Psoriasis

Mutation

Liver

Generation of infectious recombinant human rotaviruses from just 11 cloned cDNAs encoding the rotavirus genome

Komoto, S., Fukuda, S., Kugita, M., Hatazawa, R., Koyama, C., Katayama, K., Murata, T. & Taniguchi, K., 01-01-2019, In : Journal of Virology. 93, 8, Y.

Research output: Contribution to journal › Article

Rotavirus

Complementary DNA

Genome

genome

plasmids

6 Citations (Scopus)

Genetic and phenotypic landscape of the major histocompatibilty complex region in the Japanese population

Hirata, J., Hosomichi, K., Sakaue, S., Kanai, M., Nakaoka, H., Ishigaki, K., Suzuki, K., Akiyama, M., Kishikawa, T., Ogawa, K., Masuda, T., Yamamoto, K., Hirata, M., Matsuda, K., Momozawa, Y., Inoue, I., Kubo, M., Kamatani, Y. & Okada, Y., 01-03-2019, In : Nature Genetics. 51, 3, p. 470-480 11 p.

Research output: Contribution to journal › Article

HLA Antigens

Phenotype

Population

Genes

Genome-Wide Association Study

1 Citation (Scopus)

Genetic effects on white matter integrity in drug-naive patients with major depressive disorder: A diffusion tensor imaging study of 17 genetic loci associated with depressive symptoms

Kakeda, S., Watanabe, K., Katsuki, A., Sugimoto, K., Ueda, I., Igata, N., Kishi, T., Iwata, N., Abe, O., Yoshimura, R. & Korogi, Y., 01-01-2019, In : Neuropsychiatric Disease and Treatment. 15, p. 375-383 9 p.

Research output: Contribution to journal › Article

Open Access

Diffusion Tensor Imaging

Genetic Loci

Major Depressive Disorder

Depression

Single Nucleotide Polymorphism

1 Citation (Scopus)

Genome-wide association analysis of common genetic variants of resistant hypertension

on behalf of eMERGE network, 01-06-2019, In : Pharmacogenomics Journal. 19, 3, p. 295-304 10 p.

Research output: Contribution to journal › Article

Genome-Wide Association Study

Hypertension

Odds Ratio

trandolapril

Hispanic Americans

2 Citations (Scopus)

Genome-Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol

Brackman, D. J., Yee, S. W., Enogieru, O. J., Shaffer, C., Ranatunga, D., Denny, J. C., Wei, W. Q., Kamatani, Y., Kubo, M., Roden, D. M., Jorgenson, E. & Giacomini, K. M., 01-01-2019, In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journal › Article

Allopurinol

Genome-Wide Association Study

Pharmacology

Oxypurinol

Uric Acid

1 Citation (Scopus)

Genome-wide association studies identify polygenic effects for completed suicide in the Japanese population

Otsuka, I., Akiyama, M., Shirakawa, O., Okazaki, S., Momozawa, Y., Kamatani, Y., Izumi, T., Numata, S., Takahashi, M., Boku, S., Sora, I., Yamamoto, K., Ueno, Y., Toda, T., Kubo, M. & Hishimoto, A., 01-11-2019, In : Neuropsychopharmacology. 44, 12, p. 2119-2124 6 p.

Research output: Contribution to journal › Article

Genome-Wide Association Study

Suicide

Population

Single Nucleotide Polymorphism

Japan

4 Citations (Scopus)

Genome-wide association study detected novel susceptibility genes for schizophrenia and shared trans-populations/diseases genetic effect

Ikeda, M., Takahashi, A., Kamatani, Y., Momozawa, Y., Saito, T., Kondo, K., Shimasaki, A., Kawase, K., Sakusabe, T., Iwayama, Y., Toyota, T., Wakuda, T., Kikuchi, M., Kanahara, N., Yamamori, H., Yasuda, Y., Watanabe, Y., Hoya, S., Aleksic, B., Kushima, I. & 12 others, Arai, H., Takaki, M., Hattori, K., Kunugi, H., Okahisa, Y., Ohnuma, T., Ozaki, N., Someya, T., Hashimoto, R., Yoshikawa, T., Kubo, M. & Iwata, N., 01-01-2019, In : Schizophrenia Bulletin. 45, 4, p. 824-834 11 p.

Research output: Contribution to journal › Article

Genome-Wide Association Study

Population Genetics

Schizophrenia

Genes

Bipolar Disorder

Genome-wide association study identifies a novel locus associated with psychological distress in the Japanese population

Koshimizu, H., Nogawa, S., Asano, S., Ikeda, M., Iwata, N., Takahashi, S., Saito, K. & Miyakawa, T., 01-12-2019, In : Translational psychiatry. 9, 1, 52.

Research output: Contribution to journal › Article

Genome-Wide Association Study

Major Depressive Disorder

Psychology

Population

Far East

1 Citation (Scopus)

Genome-wide association study of cervical cancer suggests a role for ARRDC3 gene in human papillomavirus infection

Takeuchi, F., Kukimoto, I., Li, Z., Li, S., Li, N., Hu, Z., Takahashi, A., Inoue, S., Yokoi, S., Chen, J., Hang, D., Kuroda, M., Matsuda, F., Mizuno, M., Mori, S., Wu, P., Tanaka, N., Matsuo, K., Kamatani, Y., Kubo, M. & 2 others, Ma, D. & Shi, Y., 15-01-2019, In : Human molecular genetics. 28, 2, p. 341-348 8 p.

Research output: Contribution to journal › Article

Arrestin

Papillomavirus Infections

Genome-Wide Association Study

Uterine Cervical Neoplasms

Single Nucleotide Polymorphism

Genomic characterization of uncommon human G3P[6] rotavirus strains that have emerged in Kenya after rotavirus vaccine introduction, and pre-vaccine human G8P[4] rotavirus strains

Wandera, E. A., Komoto, S., Mohammad, S., Ide, T., Bundi, M., Nyangao, J., Kathiiko, C., Odoyo, E., Galata, A., Miring'u, G., Fukuda, S., Hatazawa, R., Murata, T., Taniguchi, K. & Ichinose, Y., 03-2019, In : Infection, Genetics and Evolution. 68, p. 231-248 18 p.

Research output: Contribution to journal › Article

Rotavirus Vaccines

Rotavirus

Kenya

vaccine

genomics

4 Citations (Scopus)

Genomic Heterogeneity Within Individual Prostate Cancer Foci Impacts Predictive Biomarkers of Targeted Therapy

VanderWeele, D. J., Finney, R., Katayama, K., Gillard, M., Paner, G., Imoto, S., Yamaguchi, R., Wheeler, D., Lack, J., Cam, M., Pontier, A., Nguyen, Y. T. M., Maejima, K., Sasaki-Oku, A., Nakano, K., Tanaka, H., Vander Griend, D., Kubo, M., Ratain, M. J., Miyano, S. & 1 others, Nakagawa, H., 05-2019, In : European Urology Focus. 5, 3, p. 416-424 9 p.

Research output: Contribution to journal › Article

Prostatic Neoplasms

Biomarkers

Therapeutics

Exome

Survival

32 Citations (Scopus)

GLIM Criteria for the Diagnosis of Malnutrition: A Consensus Report From the Global Clinical Nutrition Community

Jensen, G. L., Cederholm, T., Correia, M. I. T. D., Gonzalez, M. C., Fukushima, R., Higashiguchi, T., de Baptista, G. A., Barazzoni, R., Blaauw, R., Coats, A. J. S., Crivelli, A., Evans, D. C., Gramlich, L., Fuchs-Tarlovsky, V., Keller, H., Llido, L., Malone, A., Mogensen, K. M., Morley, J. E., Muscaritoli, M. & 13 others, Nyulasi, I., Pirlich, M., Pisprasert, V., de van der Schueren, M., Siltharm, S., Singer, P., Tappenden, K. A., Velasco, N., Waitzberg, D. L., Yamwong, P., Yu, J., Compher, C. & Van Gossum, A., 01-2019, In : Journal of Parenteral and Enteral Nutrition. 43, 1, p. 32-40 9 p.

Research output: Contribution to journal › Article

Malnutrition

Consensus

Sarcopenia

Cachexia

Validation Studies

78 Citations (Scopus)

GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community

GLIM Core Leadership Committee & GLIM Working Group, 02-2019, In : Clinical Nutrition. 38, 1, p. 1-9 9 p.

Research output: Contribution to journal › Article

Open Access

Malnutrition

Consensus

Sarcopenia

Cachexia

Validation Studies

11 Citations (Scopus)

GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community

GLIM Core Leadership Committee, GLIM Working Group, 02-2019, In : Journal of Cachexia, Sarcopenia and Muscle. 10, 1, p. 207-217 11 p.

Research output: Contribution to journal › Article

Open Access

Malnutrition

Consensus

Sarcopenia

Cachexia

Validation Studies

35 Citations (Scopus)

Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

GBD 2016 Neurology Collaborators, 05-2019, In : The Lancet Neurology. 18, 5, p. 459-480 22 p.

Research output: Contribution to journal › Article

Open Access

Nervous System Diseases

Migraine Disorders

Meningitis

Cause of Death

Tension-Type Headache

27 Citations (Scopus)

Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

GBD 2016 Stroke Collaborators, 05-2019, In : The Lancet Neurology. 18, 5, p. 439-458 20 p.

Research output: Contribution to journal › Article

Open Access

Stroke

Quality-Adjusted Life Years

Demography

Mortality

Uncertainty

Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult

Mohiuddin, M. S., Himeno, T., Inoue, R., Miura-Yura, E., Yamada, Y., Nakai-Shimoda, H., Asano, S., Kato, M., Motegi, M., Kondo, M., Seino, Y., Tsunekawa, S., Kato, Y., Suzuki, A., Naruse, K., Kato, K., Nakamura, J. & Kamiya, H., 01-01-2019, In : Journal of Diabetes Research. 2019, 9426014.

Research output: Contribution to journal › Article

Open Access

Diabetic Neuropathies

Spinal Ganglia

Neurons

Neurites

Cyclic AMP

5 Citations (Scopus)

Greater Nutrient Intake Is Associated With Lower Mortality in Western and Eastern Critically Ill Patients With Low BMI: A Multicenter, Multinational Observational Study

Compher, C., Chittams, J., Sammarco, T., Higashibeppu, N., Higashiguchi, T. & Heyland, D. K., 01-2019, In : Journal of Parenteral and Enteral Nutrition. 43, 1, p. 63-69 7 p.

Research output: Contribution to journal › Article

Critical Illness

Observational Studies

Body Mass Index

Food

Mortality

2 Citations (Scopus)

Group-level and functional-region analysis of electric-field shape during cerebellar transcranial direct current stimulation with different electrode montages

Gomez-Tames, J., Asai, A., Mikkonen, M., Laakso, I., Tanaka, S., Uehara, S., Otaka, Y. & Hirata, A., 01-01-2019, In : Journal of Neural Engineering. 16, 3, 036001.

Research output: Contribution to journal › Article

Electrodes

Electric fields

Cerebellum

Atlases

Cerebrospinal fluid

5 Citations (Scopus)

Guidelines for office gynecology in Japan: Japan Society of Obstetrics and Gynecology (JSOG) and Japan Association of Obstetricians and Gynecologists (JAOG) 2017 edition

Kawaguchi, R., Matsumoto, K., Akira, S., Ishitani, K., Iwasaku, K., Ueda, Y., Okagaki, R., Okano, H., Oki, T., Koga, K., Kido, M., Kurabayashi, T., Kuribayashi, Y., Sato, Y., Shiina, K., Takai, Y., Tanimura, S., Chaki, O., Terauchi, M., Todo, Y. & 14 others, Noguchi, Y., Nose-Ogura, S., Baba, T., Hirasawa, A., Fujii, T., Fujii, T., Maruyama, T., Miyagi, E., Yanagida, K., Yoshino, O., Iwashita, M., Maeda, T., Minegishi, T. & Kobayashi, H., 01-04-2019, In : Journal of Obstetrics and Gynaecology Research. 45, 4, p. 766-786 21 p.

Research output: Contribution to journal › Article

Gynecology

Obstetrics

Japan

Guidelines

Endocrinology

6 Citations (Scopus)

Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease

Kikuchi, K., Saigusa, D., Kanemitsu, Y., Matsumoto, Y., Thanai, P., Suzuki, N., Mise, K., Yamaguchi, H., Nakamura, T., Asaji, K., Mukawa, C., Tsukamoto, H., Sato, T., Oikawa, Y., Iwasaki, T., Oe, Y., Tsukimi, T., Fukuda, N. N., Ho, H. J., Nanto-Hara, F. & 36 others, Ogura, J., Saito, R., Nagao, S., Ohsaki, Y., Shimada, S., Suzuki, T., Toyohara, T., Mishima, E., Shima, H., Akiyama, Y., Akiyama, Y., Ichijo, M., Matsuhashi, T., Matsuo, A., Ogata, Y., Yang, C. C., Suzuki, C., Breeggemann, M. C., Heymann, J., Shimizu, M., Ogawa, S., Takahashi, N., Suzuki, T., Owada, Y., Kure, S., Mano, N., Soga, T., Wada, T., Kopp, J. B., Fukuda, S., Hozawa, A., Yamamoto, M., Ito, S., Wada, J., Tomioka, Y. & Abe, T., 01-12-2019, In : Nature Communications. 10, 1, 1835.

Research output: Contribution to journal › Article

Open Access

kidney diseases

Albuminuria

Diabetic Nephropathies

Sulfates

sulfates

1 Citation (Scopus)

GWAS analysis reveals a significant contribution of PSCA to the risk of Heliobacter pylori-induced gastric atrophy

Hishida, A., Ugai, T., Fujii, R., Nakatochi, M., Wu, M. C., Ito, H., Oze, I., Tajika, M., Niwa, Y., Nishiyama, T., Nakagawa-Senda, H., Suzuki, S., Koyama, T., Matsui, D., Watanabe, Y., Kawaguchi, T., Matsuda, F., Momozawa, Y., Kubo, M., Naito, M. & 2 others, Matsuo, K. & Wakai, K., 04-07-2019, In : Carcinogenesis. 40, 5, p. 661-668 8 p.

Research output: Contribution to journal › Article

Genome-Wide Association Study

Pylorus

Atrophy

Prostate

Stomach

GWAS of five gynecologic diseases and cross-trait analysis in Japanese

Masuda, T., Low, S. K., Akiyama, M., Hirata, M., Ueda, Y., Matsuda, K., Kimura, T., Murakami, Y., Kubo, M., Kamatani, Y. & Okada, Y., 01-01-2019, (Accepted/In press) In : European Journal of Human Genetics.

Research output: Contribution to journal › Article

Open Access

Female Genital Diseases

Genome-Wide Association Study

Ovarian Neoplasms

Uterine Neoplasms

Endometriosis

GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation

Terao, C., Momozawa, Y., Ishigaki, K., Kawakami, E., Akiyama, M., Loh, P. R., Genovese, G., Sugishita, H., Ohta, T., Hirata, M., Perry, J. R. B., Matsuda, K., Murakami, Y., Kubo, M. & Kamatani, Y., 01-12-2019, In : Nature Communications. 10, 1, 4719.

Research output: Contribution to journal › Article

Open Access

blood cells

Y Chromosome

Genome-Wide Association Study

chromosomes

Chromosomes

1 Citation (Scopus)

GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture

Matoba, N., Akiyama, M., Ishigaki, K., Kanai, M., Takahashi, A., Momozawa, Y., Ikegawa, S., Ikeda, M., Iwata, N., Hirata, M., Matsuda, K., Kubo, M., Okada, Y. & Kamatani, Y., 01-05-2019, In : Nature Human Behaviour. 3, 5, p. 471-477 7 p.

Research output: Contribution to journal › Letter

Genetic Loci

Genome-Wide Association Study

Smoking

Linkage Disequilibrium

Tobacco Products

High-fat and high-cholesterol diet decreases phosphorylated inositol-requiring kinase-1 and inhibits autophagy process in rat liver

Naito, H., Yoshikawa-Bando, Y., Yuan, Y., Hashimoto, S., Kitamori, K., Yatsuya, H. & Nakajima, T., 01-12-2019, In : Scientific reports. 9, 1, 12514.

Research output: Contribution to journal › Article

Open Access

Autophagy

High Fat Diet

Inositol

Phosphotransferases

Cholesterol

High prevalence of equine-like G3P[8] rotavirus in children and adults with acute gastroenteritis in Thailand

Tacharoenmuang, R., Komoto, S., Guntapong, R., Upachai, S., Singchai, P., Ide, T., Fukuda, S., Ruchusatsawast, K., Sriwantana, B., Tatsumi, M., Motomura, K., Takeda, N., Murata, T., Sangkitporn, S., Taniguchi, K. & Yoshikawa, T., 01-01-2019, (Accepted/In press) In : Journal of Medical Virology.

Research output: Contribution to journal › Article

Rotavirus

Gastroenteritis

Thailand

Horses

RNA

1 Citation (Scopus)

Histopathological classification of anti-neutrophil cytoplasmic antibody-associated glomerulonephritis in a nationwide Japanese prospective 2-year follow-up cohort study

For the Research Committee of Intractable Renal Disease and the Research Committee of Intractable Vasculitis Syndrome of the Ministry of Health, Labour, and Welfare of Japan, 15-03-2019, In : Clinical and Experimental Nephrology. 23, 3, p. 387-394 8 p.

Research output: Contribution to journal › Article

Antineutrophil Cytoplasmic Antibodies

Glomerulonephritis

Cohort Studies

Kidney

Glomerular Filtration Rate

HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease

Shimizu, C., Kim, J., Eleftherohorinou, H., Wright, V. J., Hoang, L. T., Tremoulet, A. H., Franco, A., Hibberd, M. L., Takahashi, A., Kubo, M., Ito, K., Tanaka, T., Onouchi, Y., Coin, L. J. M., Levin, M., Burns, J. C. & Shike, H., 01-01-2019, In : Human Immunology.

Research output: Contribution to journal › Article

HLA-C Antigens

Mucocutaneous Lymph Node Syndrome

Amino Acid Substitution

Peptides

Alleles

HLA-DQ and RBFOX1 as susceptibility genes for an outbreak of hydrolyzed wheat allergy

Noguchi, E., Akiyama, M., Yagami, A., Hirota, T., Okada, Y., Kato, Z., Kishikawa, R., Fukutomi, Y., Hide, M., Morita, E., Aihara, M., Hiragun, M., Chinuki, Y., Okabe, T., Ito, A., Adachi, A., Fukunaga, A., Kubota, Y., Aoki, T., Aoki, Y. & 30 others, Nishioka, K., Adachi, T., Kanazawa, N., Miyazawa, H., Sakai, H., Kozuka, T., Kitamura, H., Hashizume, H., Kanegane, C., Masuda, K., Sugiyama, K., Tokuda, R., Furuta, J., Higashimoto, I., Kato, A., Seishima, M., Tajiri, A., Tomura, A., Taniguchi, H., Kojima, H., Tanaka, H., Sakai, A., Morii, W., Nakamura, M., Kamatani, Y., Takahashi, A., Kubo, M., Tamari, M., Saito, H. & Matsunaga, K., 11-2019, In : Journal of Allergy and Clinical Immunology. 144, 5, p. 1354-1363 10 p.

Research output: Contribution to journal › Article

Wheat Hypersensitivity

HLA-DQ Antigens

Disease Outbreaks

Genes

Genome-Wide Association Study

Human herpesvirus-6B infection in pediatric allogenic hematopoietic stem cell transplant patients: Risk factors and encephalitis

Miura, H., Kawamura, Y., Hattori, F., Tanaka, M., Kudo, K., Ihira, M., Yatsuya, H., Takahashi, Y., Kojima, S., Sakaguchi, H., Yoshida, N., Hama, A. & Yoshikawa, T., 01-01-2019, (Accepted/In press) In : Transplant Infectious Disease.

Research output: Contribution to journal › Article

Human Herpesvirus 6

Herpesviridae Infections

Encephalitis

Hematopoietic Stem Cells

Pediatrics

Human serum albumin redox state is associated with decreased renal function in a community-dwelling population

Fujii, R., Ueyama, J., Kanno, T., Suzuki, K., Hamajima, N., Wakai, K., Hasegawa, Y. & Kondo, T., 01-01-2019, In : American journal of physiology. Renal physiology. 316, 1, p. F214-F218

Research output: Contribution to journal › Article

Independent Living

Serum Albumin

Oxidation-Reduction

Kidney

Population

4 Citations (Scopus)

Human tyrosine hydroxylase in Parkinson’s disease and in related disorders

Nagatsu, T., Nakashima, A., Ichinose, H. & Kobayashi, K., 01-04-2019, In : Journal of Neural Transmission. 126, 4, p. 397-409 13 p.

Research output: Contribution to journal › Review article

Tyrosine 3-Monooxygenase

Parkinson Disease

Dopaminergic Neurons

Dopamine

Corpus Striatum

2 Citations (Scopus)

Hyoid Bone Movement at Rest by Peripheral Magnetic Stimulation of Suprahyoid Muscles in Normal Individuals

Kagaya, H., Ogawa, M., Mori, S., Aoyagi, Y., Shibata, S., Inamoto, Y., Mori, H. & Saito, E., 01-07-2019, In : Neuromodulation. 22, 5, p. 593-596 4 p.

Research output: Contribution to journal › Article

Hyoid Bone

Muscles

Pain

Fluoroscopy

Deglutition Disorders

Identification by nano-LC-MS/MS of NT5DC2 as a protein binding to tyrosine hydroxylase: Down-regulation of NT5DC2 by siRNA increases catecholamine synthesis in PC12D cells

Nakashima, A., Yamaguchi, H., Kodani, Y., Kaneko, Y. S., Kawata, M., Nagasaki, H., Nagatsu, T. & Ota, A., 03-09-2019, In : Biochemical and Biophysical Research Communications. 516, 4, p. 1060-1065 6 p.

Research output: Contribution to journal › Article

Tyrosine 3-Monooxygenase

Protein Binding

Small Interfering RNA

Catecholamines

Down-Regulation

6 Citations (Scopus)

Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population

Suzuki, K., Akiyama, M., Ishigaki, K., Kanai, M., Hosoe, J., Shojima, N., Hozawa, A., Kadota, A., Kuriki, K., Naito, M., Tanno, K., Ishigaki, Y., Hirata, M., Matsuda, K., Iwata, N., Ikeda, M., Sawada, N., Yamaji, T., Iwasaki, M., Ikegawa, S. & 12 others, Maeda, S., Murakami, Y., Wakai, K., Tsugane, S., Sasaki, M., Yamamoto, M., Okada, Y., Kubo, M., Kamatani, Y., Horikoshi, M., Yamauchi, T. & Kadowaki, T., 01-03-2019, In : Nature Genetics. 51, 3, p. 379-386 8 p.

Research output: Contribution to journal › Letter

Genome-Wide Association Study

Gene Frequency

Type 2 Diabetes Mellitus

Population

Acinar Cells

1 Citation (Scopus)

Identification of marker genes and pathways specific to precancerous duodenal adenomas and early stage adenocarcinomas

Sakaguchi, Y., Yamamichi, N., Tomida, S., Takeuchi, C., Kageyama-Yahara, N., Takahashi, Y., Shiogama, K., Inada, K. I., Ichinose, M., Fujishiro, M. & Koike, K., 15-02-2019, In : Journal of Gastroenterology. 54, 2, p. 131-140 10 p.

Research output: Contribution to journal › Article

Adenoma

Adenocarcinoma

Catenins

Genes

Gene Expression

Identification of rare coding variants in TYK2 protective for rheumatoid arthritis in the Japanese population and their effects on cytokine signalling

Motegi, T., Kochi, Y., Matsuda, K., Kubo, M., Yamamoto, K. & Momozawa, Y., 01-01-2019, In : Annals of the Rheumatic Diseases.

Research output: Contribution to journal › Article

Rheumatoid Arthritis

Genes

Association reactions

Cytokines

Interferons

IgA1 hinge-region clustered glycan fidelity is established early during semi-ordered glycosylation by GalNAc-T2

Stewart, T. J., Takahashi, K., Whitaker, R. H., Raska, M., Placzek, W. J., Novak, J. & Renfrow, M. B., 01-01-2019, In : Glycobiology. 29, 7, p. 543-556 14 p., cwz007.

Research output: Contribution to journal › Article

Glycosylation

Hinges

Immunoglobulin A

Polysaccharides

Site selection

2 Citations (Scopus)

Imaging scoring systems for preoperative molecular diagnoses of lower-grade gliomas

Kanazawa, T., Fujiwara, H., Takahashi, H., Nishiyama, Y., Hirose, Y., Tanaka, S., Yoshida, K. & Sasaki, H., 01-06-2019, In : Neurosurgical Review. 42, 2, p. 433-441 9 p.

Research output: Contribution to journal › Article

Glioma

Methylation

Neoplasms

Mutation

Therapeutics

Impact of fusion for adolescent idiopathic scoliosis on lung volume measured with computed tomography

Fujita, N., Yagi, M., Michikawa, T., Yamada, Y., Suzuki, S., Tsuji, O., Nagoshi, N., Okada, E., Tsuji, T., Nakamura, M., Matsumoto, M. & Watanabe, K., 01-09-2019, In : European Spine Journal. 28, 9, p. 2034-2041 8 p.

Research output: Contribution to journal › Article

Scoliosis

Tomography

Lung

Pneumonectomy

Spinal Fusion

Impact of lumbar hypolordosis on the incidence of symptomatic postoperative spinal epidural hematoma after decompression surgery for lumbar spinal canal stenosis

Fujita, N., Michikawa, T., Yagi, M., Suzuki, S., Tsuji, O., Nagoshi, N., Okada, E., Tsuji, T., Nakamura, M., Matsumoto, M. & Watanabe, K., 25-01-2019, In : European Spine Journal. 28, 1, p. 87-93 7 p.

Research output: Contribution to journal › Article

Spinal Epidural Hematoma

Spinal Stenosis

Spinal Canal

Decompression

Incidence

3 Citations (Scopus)

Impact of serum albumin levels on supratherapeutic PT-INR control and bleeding risk in atrial fibrillation patients on warfarin: A prospective cohort study

Kawai, M., Harada, M., Motoike, Y., Koshikawa, M., Ichikawa, T., Watanabe, E. & Ozaki, Y., 01-03-2019, In : IJC Heart and Vasculature. 22, p. 111-116 6 p.

Research output: Contribution to journal › Article

International Normalized Ratio

Warfarin

Serum Albumin

Atrial Fibrillation

Albumins

2 Citations (Scopus)

Improving TCR affinity on 293T cells

Ohta, R., Demachi-Okamura, A., Akatsuka, Y., Fujiwara, H. & Kuzushima, K., 01-03-2019, In : Journal of Immunological Methods. 466, p. 1-8 8 p.

Research output: Contribution to journal › Article

HEK293 Cells

Peptides

Mutation

HLA-A24 Antigen

Artificial Cells