Find Research Outputs


Tolerability of partially and extensively hydrolysed milk formulas in children with cow's milk allergy

Inuo, C., Tanaka, K., Nakajima, Y., Yamawaki, K., Matsubara, T., Iwamoto, H., Tsuge, I., Urisu, A. & Kondo, Y., 01-01-2019, In : Asia Pacific journal of clinical nutrition. 28, 1, p. 49-56 8 p.

Research output: Contribution to journalArticle

Milk Hypersensitivity
Milk Proteins

Transcranial Direct-Current Stimulation Combined with Attention to the Paretic Hand Improves Hand Performance in Stroke Patients: A Double-Blind, Sham-Controlled Study

Moriya, K., Yamaguchi, T., Otaka, Y., Kondo, K. & Tanaka, S., 01-01-2019, Biosystems and Biorobotics. Springer International Publishing, p. 829-833 5 p. (Biosystems and Biorobotics; vol. 21).

Research output: Chapter in Book/Report/Conference proceedingChapter

Transcriptional cofactor Vgll2 is required for functional adaptations of skeletal muscle induced by chronic overload

Honda, M., Tsuchimochi, H., Hitachi, K. & Ohno, S., 01-09-2019, In : Journal of Cellular Physiology. 234, 9, p. 15809-15824 16 p.

Research output: Contribution to journalArticle

Skeletal Muscle
1 Citation (Scopus)
Open Access
Prefrontal Cortex
Antidepressive Agents
Gene Expression
5 Citations (Scopus)

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

Morris, A. P., Le, T. H., Wu, H., Akbarov, A., van der Most, P. J., Hemani, G., Smith, G. D., Mahajan, A., Gaulton, K. J., Nadkarni, G. N., Valladares-Salgado, A., Wacher-Rodarte, N., Mychaleckyj, J. C., Dueker, N. D., Guo, X., Hai, Y., Haessler, J., Kamatani, Y., Stilp, A. M., Zhu, G. & 52 others, Cook, J. P., Ärnlöv, J., Blanton, S. H., de Borst, M. H., Bottinger, E. P., Buchanan, T. A., Cechova, S., Charchar, F. J., Chu, P. L., Damman, J., Eales, J., Gharavi, A. G., Giedraitis, V., Heath, A. C., Ipp, E., Kiryluk, K., Kramer, H. J., Kubo, M., Larsson, A., Lindgren, C. M., Lu, Y., Madden, P. A. F., Montgomery, G. W., Papanicolaou, G. J., Raffel, L. J., Sacco, R. L., Sanchez, E., Stark, H., Sundstrom, J., Taylor, K. D., Xiang, A. H., Zivkovic, A., Lind, L., Ingelsson, E., Martin, N. G., Whitfield, J. B., Cai, J., Laurie, C. C., Okada, Y., Matsuda, K., Kooperberg, C., Chen, Y. D. I., Rundek, T., Rich, S. S., Loos, R. J. F., Parra, E. J., Cruz, M., Rotter, J. I., Snieder, H., Tomaszewski, M., Humphreys, B. D. & Franceschini, N., 01-12-2019, In : Nature Communications. 10, 1, 29.

Research output: Contribution to journalArticle

Open Access
kidney diseases
Kidney Diseases
Glomerular Filtration Rate

Treatment for frailty does not improve complication rates in corrective surgery for adult spinal deformity

Yagi, M., Michikawa, T., Hosogane, N., Fujita, N., Okada, E., Suzuki, S., Tsuji, O., Nagoshi, N., Asazuma, T., Tsuji, T., Nakamura, M., Matsumoto, M. & Watanabe, K., 15-05-2019, In : Spine. 44, 10, p. 723-731 9 p.

Research output: Contribution to journalArticle

Odds Ratio
Outcome Assessment (Health Care)
1 Citation (Scopus)

TRPM2 confers susceptibility to social stress but is essential for behavioral flexibility

Andoh, C., Nishitani, N., Hashimoto, E., Nagai, Y., Takao, K., Miyakawa, T., Nakagawa, T., Mori, Y., Nagayasu, K., Shirakawa, H. & Kaneko, S., 01-02-2019, In : Brain Research. 1704, p. 68-77 10 p.

Research output: Contribution to journalArticle

Rotarod Performance Test
Hindlimb Suspension
Muscle Strength
Interpersonal Relations
Drug Discovery

Two siblings with 11qter deletion syndrome that had been rescued in their mother by uniparental disomy

Kawai, M., Tsutsumi, M., Suzuki, F., Sameshima, K., Dowa, Y., Kyoya, T., Inagaki, H. & Kurahashi, H., 01-03-2019, In : European Journal of Medical Genetics. 62, 3, p. 224-228 5 p.

Research output: Contribution to journalArticle

Jacobsen Distal 11q Deletion Syndrome
Uniparental Disomy
X Chromosome Inactivation
Cytogenetic Analysis

Upper limb motor function affects the outcome after treatment with botulinum toxin a

Fujimura, K., Kagaya, H., Onaka, H., Nagasawa, N., Ishihara, A., Okochi, Y., Yamada, M., Tanikawa, H., Kanada, Y. & Saito, E., 01-06-2019, In : European Neurology. 81, 1-2, p. 30-36 7 p.

Research output: Contribution to journalArticle

Botulinum Toxins
Upper Extremity
Type A Botulinum Toxins

Urodynamic 4D-CT evaluation: 320-row area detector CT scanner combined with PhyZiodynamics software analysis provides an innovative system to evaluate urinary flow and outlet obstructions

Mori, S., Yashiro, H., Inoue, M., Takahara, K., Kusaka, M. & Shiroki, R., 01-01-2019, (Accepted/In press) In : Acta Radiologica.

Research output: Contribution to journalArticle

Four-Dimensional Computed Tomography
Urinary Tract

Usefulness of Full-spectrum Endoscopy for the Upper Gastrointestinal Tract

Yamada, H., Shibata, T., Terada, T., Osaki, H., Maeda, K., Tahara, T., Nagasaka, M., Nakagawa, Y. & Omiya, N., 01-01-2019, In : Journal of Clinical Gastroenterology.

Research output: Contribution to journalArticle

Upper Gastrointestinal Tract
Digestive System Endoscopy
Ampulla of Vater
Optic Disk

Use of a cohorting-unit and systematic surveillance cultures to control a Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae outbreak

Reeme, A. E., Bowler, S. L., Buchan, B. W., Graham, M. B., Behrens, E., Singh, S., Hong, J. C., Arvan, J., Hyke, J. W., Palen, L., Savage, S., Seliger, H., Huerta, S., Ledeboer, N. A., Kotay, S., Mathers, A. J., Cooper, V. S., Mustapha, M. M., Mettus, R. T., Doi, Y. & 1 others, Munoz-Price, L. S., 01-07-2019, In : Infection Control and Hospital Epidemiology. 40, 7, p. 767-773 7 p.

Research output: Contribution to journalArticle

Klebsiella pneumoniae
Disease Outbreaks
Infection Control
1 Citation (Scopus)

Utility of the Serum Cystatin C level for diagnosis of osteoporosis among middle-aged and elderly people

Tanaka, S., Ando, K., Kobayashi, K., Hida, T., Ito, K., Tsushima, M., Morozumi, M., Machino, M., Ota, K., Suzuki, K., Seki, T., Ishiguro, N., Hasegawa, Y. & Imagama, S., 01-01-2019, In : BioMed Research International. 2019, 5046852.

Research output: Contribution to journalArticle

Cystatin C
1 Citation (Scopus)

UV irradiation-induced DNA hypomethylation around WNT1 gene: Implications for solar lentigines

Yamada, T., Hasegawa, S., Iwata, Y., Arima, M., Kobayashi, T., Numata, S., Nakata, S., Sugiura, K. & Akamatsu, H., 01-06-2019, In : Experimental Dermatology. 28, 6, p. 723-729 7 p.

Research output: Contribution to journalArticle


Validation of the japanese version of the yale food addiction scale 2.0 (J-YFAS 2.0)

Khine, M. T., Ota, A., Gearhardt, A. N., Fujisawa, A., Morita, M., Minagawa, A., Li, Y., Naito, H. & Yatsuya, H., 01-03-2019, In : Nutrients. 11, 3, 687.

Research output: Contribution to journalArticle

Open Access
signs and symptoms (animals and humans)
college students

Vangl2 interaction plays a role in the proteasomal degradation of Prickle2

Nagaoka, T., Furuse, M., Ohtsuka, T., Tsuchida, K. & Kishi, M., 01-12-2019, In : Scientific Reports. 9, 1, 2912.

Research output: Contribution to journalArticle

Open Access
Cell Polarity
LIM Domain Proteins
Proteasome Inhibitors
Ubiquitin-Protein Ligases

Velopharyngeal closure analysis using four-dimensional computed tomography: A pilot study of healthy volunteers and adult patients with cleft palate

Kobayashi, Y., Kanamori, D., Fujii, N., Kataoka, Y., Hirai, E., Yoshioka, S., Satoh, K., Toyama, H., Naito, K. & Matsuo, K., 08-07-2019, In : BMC Medical Imaging. 19, 1, 54.

Research output: Contribution to journalArticle

Open Access
Four-Dimensional Computed Tomography
Velopharyngeal Insufficiency
Cleft Palate
Healthy Volunteers

Video-assisted thoracoscopic surgery for ectopic mediastinal parathyroid tumor: Subxiphoid and lateral thoracic approach

Nagano, H., Suda, T., Ishizawa, H., Negi, T., Kawai, H., Kawakami, T., Tochii, D., Tochii, S. & Hoshikawa, Y., 01-07-2019, In : Journal of Thoracic Disease. 11, 7, p. 2932-2938 7 p.

Research output: Contribution to journalArticle

Video-Assisted Thoracic Surgery
Parathyroid Neoplasms
1 Citation (Scopus)

Warm ischemic time as a critical risk factor of graft failure from donors after cardiac death: A single-center experience over three decades in the Kidney Donor Profile Index/Kidney Donor Risk Index era in Japan

Kusaka, M., Kubota, Y., Takahashi, H., Sasaki, H., Kawai, A., Takenaka, M., Fukami, N., Kenmochi, T., Shiroki, R. & Hoshinaga, K., 01-02-2019, In : International Journal of Urology. 26, 2, p. 247-252 6 p.

Research output: Contribution to journalArticle

Warm Ischemia
Graft Survival

Wavelet p-Leader Non Gaussian Multiscale Expansions for Heart Rate Variability Analysis in Congestive Heart Failure Patients

Wendt, H., Abry, P., Kiyono, K., Hayano, J., Watanabe, E. & Yamamoto, Y., 01-01-2019, In : IEEE Transactions on Biomedical Engineering. 66, 1, p. 80-88 9 p., 8336968.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Working hours and risk of acute myocardial infarction and stroke among middle-aged japanese men: The Japan public health center-based prospective study cohort II

for the Japan Public Health Center-Based (JPHC) Prospective Study Group, 01-01-2019, In : Circulation Journal. 83, 5, p. 1072-1079 8 p.

Research output: Contribution to journalArticle

Open Access
Public Health
Myocardial Infarction
Prospective Studies
2 Citations (Scopus)

A 20-year prospective longitudinal study of degeneration of the cervical spine in a volunteer cohort assessed using MRI follow-up of a cross-sectional study

Daimon, K., Fujiwara, H., Nishiwaki, Y., Okada, E., Nojiri, K., Watanabe, M., Katoh, H., Shimizu, K., Ishihama, H., Fujita, N., Tsuji, T., Nakamura, M., Matsumoto, M. & Watanabe, K., 01-01-2018, In : Journal of Bone and Joint Surgery - American Volume. 100, 10, p. 843-849 7 p.

Research output: Contribution to journalArticle

Longitudinal Studies
Cross-Sectional Studies
Magnetic Resonance Imaging

A basic study on self-reconstitution of alveolar epithelium-like cells by tissue stem cells in mouse lung

Hayashi, M., Yamamoto, N., Hiramatsu, N., Isogai, S., Gotoh, Y., Goto, Y., Kondo, M. & Imaizumi, K., 01-10-2018, In : In Vitro Cellular and Developmental Biology - Animal. 54, 9, p. 648-657 10 p.

Research output: Contribution to journalArticle

Stem Cells

Absence of fosfomycin resistance in gastrointestinal Escherichia coli following fosfomycin therapy

Mettus, R. T., Bowler, S. L., Kantz, S. F., McElheny, C. L., Pasculle, A. W. & Doi, Y., 01-09-2018, In : Journal of Global Antimicrobial Resistance. 14, p. 109-110 2 p.

Research output: Contribution to journalLetter

Escherichia coli
1 Citation (Scopus)

A Case of Non-24-Hour Sleep-Wake Rhythm Disorder Treated With a Low Dose of Ramelteon and Behavioral Education

Watanabe, A., Hirose, M., Arakawa, C., Iwata, N. & Kitajima, T., 15-07-2018, In : Journal of Clinical Sleep Medicine. 14, 7, p. 1265-1267 3 p.

Research output: Contribution to journalArticle

Circadian Rhythm Sleep Disorders

A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework

Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, 25-06-2018, In : BMC Genomics. 19, 1, 494.

Research output: Contribution to journalArticle

Genome-Wide Association Study
1 Citation (Scopus)

Acquisition of resistance to androgen deprivation therapy in salivary duct carcinoma: A case report

Wasano, K., Sakurai, K., Kawasaki, T., Kusafuka, K., Kasahara, M., Kondo, N., Inada, K. I. & Ogawa, K., 01-09-2018, In : Rare Tumors. 10

Research output: Contribution to journalArticle

Open Access
Salivary Ducts
Androgen Receptors
Parotid Gland
Inservice Training
2 Citations (Scopus)

Adsorptive filtration systems for effective removal of blood amyloid β: a potential therapy for Alzheimer’s disease

Kitaguchi, N., Kawaguchi, K., Yamazaki, K., Kawachi, H., Sakata, M., Kaneko, M., Kato, M., Sakai, K., Ohashi, N., Hasegawa, M., Hiki, Y. & Yuzawa, Y., 01-06-2018, In : Journal of Artificial Organs. 21, 2, p. 220-229 10 p.

Research output: Contribution to journalArticle

Alzheimer Disease
2 Citations (Scopus)

Age at first birth in women is genetically associated with increased risk of schizophrenia

Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 others, Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Del Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Haan, L. D., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Juliá, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Keong, J. L. C., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'callaghan, E., O'dushlaine, C., O'neill, F. A., Oh, S. Y., Olincy, A., Olsen, L., Os, J. V., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Stroup, T. S., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Cichon, S., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Rietschel, M., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, T., Daly, M. J., Sullivan, P. F. & O'donovan, M. C., 01-12-2018, In : Scientific reports. 8, 1, 10168.

Research output: Contribution to journalArticle

Birth Order
Mental Health
Genetic Heterogeneity
1 Citation (Scopus)

A genome-wide association study identifies three novel genetic markers for response to tamoxifen: A prospective multicenter study

Onishi, H., Udagawa, C., Kubo, M., Nakamura, S., Akashi-Tanaka, S., Kuwayama, T., Watanabe, C., Takamaru, T., Takei, H., Ishikawa, T., Miyahara, K., Matsumoto, H., Hasegawa, Y., Momozawa, Y., Low, S. K., Kutomi, G., Shima, H., Satomi, F., Okazaki, M., Zaha, H. & 14 others, Onomura, M., Matsukata, A., Sagara, Y., Baba, S., Yamada, A., Shimada, K., Shimizu, D., Tsugawa, K., Shimo, A., Hartman, M., Chan, C. W., Lee, S. C., Endo, I. & Zembutsu, H., 01-08-2018, In : PloS one. 13, 8, e0201606.

Research output: Contribution to journalArticle

Open Access
Genome-Wide Association Study
prospective studies
Genetic Markers
20 Citations (Scopus)

A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder

Advanced Collaborative Study of Mood Disorder (COSMO) team, 01-03-2018, In : Molecular Psychiatry. 23, 3, p. 639-647 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Regulator Genes
6 Citations (Scopus)

A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study

Nakagawa-Senda, H., Hachiya, T., Shimizu, A., Hosono, S., Oze, I., Watanabe, M., Matsuo, K., Ito, H., Hara, M., Nishida, Y., Endoh, K., Kuriki, K., Katsuura-Kamano, S., Arisawa, K., Nindita, Y., Ibusuki, R., Suzuki, S., Hosono, A., Mikami, H., Nakamura, Y. & 16 others, Takashima, N., Nakamura, Y., Kuriyama, N., Ozaki, E., Furusyo, N., Ikezaki, H., Nakatochi, M., Sasakabe, T., Kawai, S., Okada, R., Hishida, A., Naito, M., Wakai, K., Momozawa, Y., Kubo, M. & Tanaka, H., 01-12-2018, In : Scientific reports. 8, 1, 1493.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Cohort Studies
16 Citations (Scopus)

A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes

Van Zuydam, N. R., Ahlqvist, E., Sandholm, N., Deshmukh, H., William Rayner, N., Abdalla, M., Ladenvall, C., Ziemek, D., Fauman, E., Robertson, N. R., McKeigue, P. M., Valo, E., Forsblom, C., Harjutsalo, V., Perna, A., Rurali, E., Loredana Marcovecchio, M., Igo, R. P., Salem, R. M., Perico, N. & 578 others, Lajer, M., Käräjämäki, A., Imamura, M., Kubo, M., Takahashi, A., Sim, X., Liu, J., Van Dam, R. M., Jiang, G., Tam, C. H. T., Luk, A. O. Y., Lee, H. M., Lim, C. K. P., Szeto, C. C., So, W. Y., Chan, J. C. N., Ang, S. F., Dorajoo, R., Wang, L., Clara, T. S. H., McKnight, A. J., Duffy, S., Warren, Pezzolesi, M. G., Marre, M., Gyorgy, B., Hadjadj, S., Hiraki, L. T., Ahluwalia, T. S., Almgren, P., Schulz, C. A., Orho-Melander, M., Linneberg, A., Christensen, C., Witte, D. R., Grarup, N., Brandslund, I., Melander, O., Paterson, A. D., Tregouet, D., Maxwell, A. P., Lim, S. C., Ma, R. C. W., Shyong Tai, E., Maeda, S., Lyssenko, V., Tuomi, T., Krolewski, A. S., Rich, S. S., Hirschhorn, J. N., Florez, J. C., Dunger, D., Pedersen, O., Hansen, T., Rossing, P., Remuzzi, G., Brosnan, M. J., Palmer, C. N. A., Groop, P. H., Colhoun, H. M., Groop, L. C., McCarthy, M. I., Koivula, S., Uggeldahl, T., Forslund, T., Halonen, A., Koistinen, A., Koskiaho, P., Laukkanen, M., Saltevo, J., Tiihonen, M., Forsen, M., Granlund, H., Jonsson, A. C., Nyroos, B., Kinnunen, P., Orvola, A., Salonen, T., Vähänen, A., Paldanius, K. R., Riihelä, M., Ryysy, L., Laukkanen, K. H., Nyländen, P., Sademies, A., Anderson, S., Asplund, B., Byskata, U., Liedes, P., Kuusela, M., Virkkala, T., Nikkola, A., Ritola, E., Niska, T. M., Saarinen, H., Oukko-Ruponen, S. E., Virtanen, T., Lyytinen, V. A., Kari, P. H., Simonen, T., Kaprio, S. A., Kärkkäinen, J., Rantaeskola, B., Kääriäinen, T. P., Haaga, J., Pietiläinen, A. L., Klemetti, S., Nyandoto, T., Rontu, E., Satuli-Autere, S., Toivonen, K. R., Lansimaki, H. V., Ahonen, R., Ivaska-Suomela, M., Jauhiainen, A., Laine, M. M., Pellonpää, T., Puranen, R., Airas, M. A., Laakso, J., Rautavaara, K., Erola, R. M., Jatkola, E., Lönnblad, T. R., Malm, A., Mäkelä, J., Rautamo, E., Hentunen, P., Lagerstam, J., Feodoroff, M., Gordin, D., Heikkilä, O., Hietala, K., Fagerudd, J., Korolainen, M., Kyllönen, L., Kytö, J., Lindh, S., Pettersson-Fernholm, K., Rosengård-Bärlund, M., Sandelin, A., Thorn, L., Tuomikangas, J., Vesisenaho, T., Wadén, J., Sipilä, V., Kalliomäki, F. T., Koskelainen, J., Nikkanen, R., Savolainen, N., Sulonen, H., Valtonen, E., Norvio, L., Hämäläinen, A., Toivanen, E., Parta, J. A., Pirttiniemi, I., Aranko, S., Ervasti, S., Kauppinen-Mäkelin, R., Kuusisto, A., Leppälä, T., Nikkilä, K., Pekkonen, L., Jokelainen, K. S., Kananen, K., Karjalainen, M., Kemppainen, P., Mankinen, A. M., Reponen, A., Sankari, M., Suominen, P., Lappalainen, A., Liimatainen, M., Santaholma, J., Aimolahti, A., Huovinen, E., Ilkka, V., Lehtimäki, M., Pälikkö-Kontinen, E., Vanhanen, A., Koskinen, E., Siitonen, T., Huttunen, E., Ikäheimo, R., Karhapää, P., Kekäläinen, P., Laakso, M., Lakka, T., Lampainen, E., Moilanen, L., Tanskanen, S., Niskanen, L., Tuovinen, U., Vauhkonen, I., Voutilainen, E., Huang, Y., Lan, H. Y., Lok, S., Tomlinson, B., Tsui, S. K. W., Yu, W., Yip, K. Y. L., Chan, T. F., Fan, X., Tang, N., Tian, X., Chan, K. K. H., Xie, F., Ng, A. C. W., Cheung, G. P. Y., Yeung, M. W., Mai, S., Xie, F., Zhang, S., Yu, P., Weng, M., Savage, D. A., Walker, J., Thomas, S., Viberti, G. C., Boulton, A. J. M., Marshall, S., Demaine, A. G., Millward, B. A., Bain, S. C., Mäkinen, V. P., Ahola, A. J., Dahlström, E., Gordin, D., Heikkilä, O., Hietala, K., Kytö, J., Lehto, M., Lithovius, R., Panduru, N. M., Parkkonen, M., Rosengård-Bärlund, M., Saraheimo, M., Söderlund, J., Soro-Paavonen, A., Syreeni, A., Thorn, L. M., Tolonen, N., Wadén, J., McKay, G. J., Isakova, T., Guiducci, C., Taylor, A., Mirel, D. B., Williams, W. W., Brennan, E. P., Sadlier, D. M., Martin, F., Godson, C., Mayer, L., Gubitosi-Klug, R., Bourne, P., Schutta, M., Lackaye, M. E., Gregory, N. S., Kruger, D., Jones, J. K., Bhan, A., Golden, E., Aiello, L., Larkin, M., Nathan, D., Ziegler, G., Caulder, S., Pittman, C., Luttrell, L., Lopes-Virella, M., Johnson, M., Gunyou, K., Bergenstal, R., Vittetoe, B., Sivitz, W., Flaherty, N., Bantle, J., Hitt, S., Goldstein, D., Hainsworth, D., Cimino, L., Orchard, T., Wigley, C., Dagogo-Jack, S., Strowig, S., Raskin, P., Barnie, A., Zinman, B., Fahlstrom, R., Palmer, J., Harth, J., Driscoll, M., McDonald, C., Lipps Hagan, J., May, M., Levandoski, L., White, N., Gatcomb, P., Tamborlane, W., Adelman, D., Colson, S., Molitch, M., Lorenzi, G., Mudaliar, S., Johnsonbaugh, S., Miller, R., Canady, J., Schade, D., Bernal, M. L., Malone, J., Morrison, A., Martin, C., Herman, W., Pop-Busui, R., Cowie, C., Leschek, E., Cleary, P., Lachin, J., Zinman, B., Lorenzi, G., Braffett, B., Steffes, M., Arends, V., Blodi, B., Danis, R., Lawrence, D., Wabers, H., Soliman, E., Zhang, Z. M., Campbell, C., Hensley, S., Keasler, L., Mark, M., Albertini, M., Boustany, C., Ehlgen, A., Gerl, M., Huber, J., Schölch, C., Zimdahl-Gelling, H., Agardh, E., Ajanki, T., Al Maghrabi, N., Apelqvist, J., Bengtsson, E., Berglund, L., Björckbacka, H., Blom-Nilsson, U., Borell, M., Burström, A., Cilio, C., Cinthio, M., Dreja, K., Dunér, P., Engelbertsen, D., Fadista, J., Gomez, M., Goncalves, I., Hedblad, B., Hultgårdh, A., Johansson, M. E., Kennbäck, C., Kravic, J., Lernmark, A., Lindholm, E., Ling, C., Luthman, H., Neptin, M., Nilsson, J., Nilsson, P., Nilsson, T., Nordin, G., Ottoson-Laakso, E., Persson, A., Persson, M., Persson, M. A., Postma, J., Pranter, E., Rattik, S., Sterner, G., Tindberg, L., Wigren, M., Zetterqvist, A., Åkerlund, M., Ostling, G., Kanninen, T., Ahonen-Bishopp, A., Eliasson, A., Herrala, T., Tikka-Kleemola, P., Hamsten, A., Betsholtz, C., Björkholm, A., Foroogh, F., Genové, G., Gertow, K., Gigante, B., He, B., Leander, K., McLeod, O., Nastase-Mannila, M., Patrakka, J., Silveira, A., Strawbridge, R., Tryggvason, K., Vikström, M., Ohrvik, J., Österholm, A. M., Thorand, B., Gieger, C., Grallert, H., Ludwig, T., Nitz, B., Schneider, A., Wang-Sattler, R., Zierer, A., Benigni, A., Donadelli, R., Lesti, M. D., Noris, M., Piras, R., Ruggenenti, P., Chassin, L., Dalton, N., Deanfield, J., Horsford, J., Rice, C., Rudd, J., Walker, N., Whitehead, K., Wong, M., Adams, F., Akbar, T., Belch, J., Dove, F., Ellingford, A., Farran, B., Ferguson, M., Henderson, G., Houston, G., Khan, F., Leese, G., Livingstone, S., Looker, H., McCann, M., McGurnaghan, S., Morris, A., Newton, D., Pearson, E., Reekie, G., Smith, N., Shore, A., Aizawa, K., Ball, C., Bellenger, N., Casanova, F., Frayling, T., Gates, P., Gooding, K., Hattersley, A., Ling, R., Mawson, D., Shandas, R., Strain, D., Thorn, C., Smith, U., Hammarstedt, A., Häring, H., Sesti, G., Fagerholm, E., Parkkonen, M., Tolonen, N., Toppila, I., Salomaa, V., Havulinna, A., Kristiansson, K., Okamo, P., Peltola, T., Perola, M., Pietilä, A., Ripatti, S., Taimi, M., Ylä-Herttuala, S., Babu, M., Dijkstra, M., Gurzeler, E., Huusko, J., Kholová, I., Laakso, M., Merentie, M., Poikolainen, M., Groves, C., Juliusdottir, T., Karpe, F., Lagou, V., Morris, A., Cobelli, C., Di Camillo, B., Finotello, F., Sambo, F., Toffolo, G., Trifoglio, E., Bellazzi, R., Barbarini, N., Bucalo, M., Larizza, C., Magni, P., Malovini, A., Marini, S., Mulas, F., Quaglini, S., Sacchi, L., Vitali, F., Ferrannini, E., Boldrini, B., Kozakova, M., Mari, A., Morizzo, C., Mota, L., Natali, A., Palombo, C., Venturi, E., Walker, M., Patrono, C., Pagliaccia, F., Rocca, B., Nuutila, P., Haukkala, J., Knuuti, J., Roivainen, A., Saraste, A., McKeague, P., Colombo, M., Steckel-Hamann, B., Bokvist, K., Shankar, S., Thomas, M., Gan, L. M., Heinonen, S., Jönsson-Rylander, A. C., Momo, R., Schnecke, V., Unwin, R., Walentinsson, A., Whatling, C., Nogoceke, E., Pacheco, G. D., Formentini, I., Schindler, T., Tortoli, P., Bassi, L., Boni, E., Dallai, A., Guidi, F., Lenge, M., Matera, R., Ramalli, A., Ricci, S., Viti, J., Jablonka, B., Crowther, D., Gassenhuber, J., Hess, S., Hubschle, T., Juretschke, H. P., Rutten, H., Sadowski, T., Wohlfart, P., Clerin, V., Hyde, C., Malarstig, A., Pullen, N., Tilley, M., Tuthill, T. & Vangjeli, C., 01-07-2018, In : Diabetes. 67, 7, p. 1414-1427 14 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Diabetic Nephropathies
Type 2 Diabetes Mellitus
Glomerular Filtration Rate
4 Citations (Scopus)

Age-related declines in the ability to modulate common input to bilateral and unilateral plantar flexors during forward postural lean

Watanabe, T., Saito, K., Ishida, K., Tanabe, S. & Nojima, I., 25-06-2018, In : Frontiers in Human Neuroscience. 12, 254.

Research output: Contribution to journalArticle

Skeletal Muscle
Young Adult
3 Citations (Scopus)

A high level of blood urea nitrogen is a significant predictor for in-hospital mortality in patients with acute myocardial infarction

J-MINUET investigators, 01-01-2018, In : International heart journal. 59, 2, p. 263-271 9 p.

Research output: Contribution to journalArticle

Blood Urea Nitrogen
Hospital Mortality
Myocardial Infarction
Odds Ratio
Confidence Intervals

A hypoglycemia-inducing giant borderline phyllodes tumor secreting high-molecular-weight insulin-like growth factor II: Immunohistochemistry and a western blot analysis

Hikichi, M., Kiriyama, Y., Hayashi, T., Ushimado, K., Kobayashi, N., Urano, M., Kuroda, M. & Utsumi, T., 01-01-2018, In : Internal Medicine. 57, 2, p. 237-241 5 p.

Research output: Contribution to journalArticle

Phyllodes Tumor
Insulin-Like Growth Factor II
Molecular Weight
Western Blotting
7 Citations (Scopus)

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

The CHARGE Neurology Working Group, The COGENT-Kidney Consortium, The GIANT Consortium & Lifelines Cohort Study, 01-03-2018, In : American Journal of Human Genetics. 102, 3, p. 375-400 26 p.

Research output: Contribution to journalArticle

Blood Pressure
Genome-Wide Association Study
Blood Vessels
2 Citations (Scopus)

A lower eicosapentaenoic acid/arachidonic acid ratio is associated with in-hospital fatal arrhythmic events in patients with acute myocardial infarction: a J-MINUET substudy

on behalf of J-MINUET Investigators, 01-05-2018, In : Heart and Vessels. 33, 5, p. 481-488 8 p.

Research output: Contribution to journalArticle

Eicosapentaenoic Acid
Arachidonic Acid
Myocardial Infarction
Ventricular Fibrillation
Ventricular Tachycardia
1 Citation (Scopus)

Amino acid position 37 of HLA-DRβ1 affects susceptibility to Crohn's disease in Asians

Han, B., Akiyama, M., Kim, K. K., Oh, H., Choi, H., Lee, C. H., Jung, S., Lee, H. S., Kim, E. E., Cook, S., Haritunians, T., Yamazaki, K., Park, S. H., Ye, B. D., McGovern, D. P. B., Esaki, M., Kawaguchi, T., Khor, S. S., Taylor, K. D., Rotter, J. I. & 12 others, Suzuki, Y., Matsui, T., Motoya, S., Bang, S. Y., Kim, T. H., Momozawa, Y., Kamatani, Y., Tokunaga, K., Kubo, M., Okada, Y., Yang, S. K. & Song, K., 01-11-2018, In : Human molecular genetics. 27, 22, p. 3901-3910 10 p.

Research output: Contribution to journalArticle

HLA Antigens
Crohn Disease
Amino Acids
Ulcerative Colitis
Inflammatory Bowel Diseases
2 Citations (Scopus)

A multicenter prospective cohort study to develop frailty-based prognostic criteria in heart failure patients (FLAGSHIP): Rationale and design

on behalf of the FLAGSHIP collaborators, 02-08-2018, In : BMC Cardiovascular Disorders. 18, 1, 159.

Research output: Contribution to journalArticle

Cohort Studies
Heart Failure
Prospective Studies
Practice Guidelines
4 Citations (Scopus)

A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis

Japan Scoliosis Clinical Research Group (JSCRG) & Texas Scottish Rite Hospital for Children Clinical Group (TSRHCCG), 01-12-2018, In : Scientific reports. 8, 1, 11575.

Research output: Contribution to journalArticle

Open Access
Genome-Wide Association Study
Far East
Computer Simulation

Analysis of variability of R-R intervals for the diagnosis of atrial fibrillation: A new algorithm

Matsui, T., Shinozaki, R., Watanabe, E. & Aizawa, Y., 01-05-2018, In : Journal of Electrocardiology. 51, 3, p. 382-385 4 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Sensitivity and Specificity
14 Citations (Scopus)

Anamorelin (ONO-7643) for the treatment of patients with non–small cell lung cancer and cachexia: Results from a randomized, double-blind, placebo-controlled, multicenter study of Japanese patients (ONO-7643-04)

Katakami, N., Uchino, J., Yokoyama, T., Naito, T., Kondo, M., Yamada, K., Kitajima, H., Yoshimori, K., Sato, K., Saito, H., Aoe, K., Tsuji, T., Takiguchi, Y., Takayama, K., Komura, N., Takiguchi, T. & Eguchi, K., 01-02-2018, In : Cancer. 124, 3, p. 606-616 11 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Multicenter Studies

A novel design of rat's head positioner for MRI and its feasibility

Narita, H. & Yamada, M., 01-01-2018, In : Journal of Advanced Mechanical Design, Systems and Manufacturing. 12, 6, JAMDSM0116.

Research output: Contribution to journalArticle

Magnetic resonance imaging
3D printers
2 Citations (Scopus)

A novel IFIH1 mutation in the pincer domain underlies the clinical features of both Aicardi–Goutières and Singleton–Merten syndromes in a single patient

Takeichi, T., Katayama, C., Tanaka, T., Okuno, Y., Murakami, N., Kono, M., Sugiura, K., Aoyama, Y. & Akiyama, M., 01-02-2018, In : British Journal of Dermatology. 178, 2, p. e111-e113

Research output: Contribution to journalLetter

Singleton Merten syndrome
2 Citations (Scopus)

Anti-dementia drugs for psychopathology and cognitive impairment in schizophrenia: A systematic review and meta-analysis

Kishi, T., Ikuta, T., Oya, K., Matsunaga, S., Matsuda, Y. & Iwata, N., 01-01-2018, In : International Journal of Neuropsychopharmacology. 21, 8, p. 748-757 10 p.

Research output: Contribution to journalReview article

Antipsychotic Agents

Anti-GM1 ganglioside antibodies modulate membrane-associated sphingomyelin metabolism by altering neutral sphingomyelinase activity

Ueda, A., Shima, S., Murate, K., Kikuchi, K., Nagao, R., Maeda, T., Muto, E., Niimi, Y., Mizutani, Y. & Mutoh, T., 01-06-2018, In : Molecular and Cellular Neuroscience. 89, p. 42-48 7 p.

Research output: Contribution to journalArticle

G(M1) Ganglioside
Sphingomyelin Phosphodiesterase
6 Citations (Scopus)

Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination

Akahori, Y., Wang, L., Yoneyama, M., Seo, N., Okumura, S., Miyahara, Y., Amaishi, Y., Okamoto, S., Mineno, J., Ikeda, H., Maki, T., Fujiwara, H., Akatsuka, Y., Kato, T. & Shiku, H., 13-09-2018, In : Blood. 132, 11, p. 1134-1145 12 p.

Research output: Contribution to journalArticle

Wilms Tumor
Oncogene Proteins
T-Cell Antigen Receptor