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• Genetic environment of 16S rRNA methylase gene rmtD

  Doi, Y., Adams-Haduch, J. M. & Paterson, D. L., 06-2008, In: Antimicrobial agents and chemotherapy. 52, 6, p. 2270-2272 3 p.

  Research output: Contribution to journal › Article › peer-review

  • rRNA (adenosine-O-2'-)methyltransferase
  • rRNA Genes
  • Pseudomonas aeruginosa
  • Integrons
  • Klebsiella pneumoniae
  15 Citations (Scopus)

• Genetic environments of the rmtA gene in Pseudomonas aeruginosa clinical isolates

  Yamane, K., Doi, Y., Yokoyama, K., Yagi, T., Kurokawa, H., Shibata, N., Shibayama, K., Kato, H. & Arakawa, Y., 06-2004, In: Antimicrobial agents and chemotherapy. 48, 6, p. 2069-2074 6 p.

  Research output: Contribution to journal › Article › peer-review

  • rRNA (adenosine-O-2'-)methyltransferase
  • rRNA Genes
  • Pseudomonas aeruginosa
  • Genes
  • Transposases
  53 Citations (Scopus)

• Genetic evidence for association between NOTCH4 and schizophrenia supported by a GWAS follow-up study in a Japanese population

  Ikeda, M., Aleksic, B., Yamada, K., Iwayama-Shigeno, Y., Matsuo, K., Numata, S., Watanabe, Y., Ohnuma, T., Kaneko, T., Fukuo, Y., Okochi, T., Toyota, T., Hattori, E., Shimodera, S., Itakura, M., Nunokawa, A., Shibata, N., Tanaka, H., Yoneda, H., Arai, H. & 5 others, Someya, T., Ohmori, T., Yoshikawa, T., Ozaki, N. & Iwata, N., 06-2013, In: Molecular Psychiatry. 18, 6, p. 636-638 3 p.

  Research output: Contribution to journal › Letter › peer-review
  27 Citations (Scopus)

• Genetic Factors Explain the Association Between Pain Catastrophizing and Chronic Widespread Pain

  Ogata, S., Williams, F. & Burri, A., 09-2017, In: Journal of Pain. 18, 9, p. 1111-1116 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Catastrophization
  • Chronic Pain
  • Genetic Structures
  • Pain Management
  • Pain
  6 Citations (Scopus)

• Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept

  Psychosis Endophenotypes International Consortium, 23-02-2016, In: Nature Neuroscience. 19, 3, p. 420-431 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Schizophrenia
  • Brain
  • Psychiatry
  • Phenotype
  • Genetic Markers
  122 Citations (Scopus)

• Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population

  Terao, C., Okada, Y., Ikari, K., Kochi, Y., Suzuki, A., Ohmura, K., Matsuo, K., Taniguchi, A., Kubo, M., Raychaudhuri, S., Yamamoto, K., Yamanaka, H., Kamatani, Y., Mimori, T. & Matsuda, F., 01-12-2017, In: Journal of Medical Genetics. 54, 12, p. 853-858 6 p.

  Research output: Contribution to journal › Article › peer-review

  • HLA-DRB1 Chains
  • Rheumatoid Arthritis
  • Alleles
  • Peptides
  • Antibodies
  2 Citations (Scopus)

• Genetic mapping of genes regulating the thymus size in back-cross rats between the laboratory BUF/Mna strain and the MITE strain derived from the wild rat, Rattus norvegicus

  Sharma, N., Ohyabu, A., Murakumo, Y., Takahashi, M., Saito, M., Amo, H., Murayama, S. I., Ohno, K., Oda, S. I. & Matsuyama, M., 1997, In: Pathology International. 47, 7, p. 436-441 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Chromosome Mapping
  • Thymus Gland
  • Chromosomes, Human, Pair 3
  • Chromosomes, Human, Pair 1
  • Genotype
  5 Citations (Scopus)

• Genetic mapping of the polycystic kidney gene, pcy, on mouse chromosome 9

  Nagao, S., Watanabe, T., Ogiso, N., Marunouchi, T. & Takahashi, H., 12-1995, In: Biochemical Genetics. 33, 11-12, p. 401-412 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Chromosomes, Human, Pair 9
  • Polycystic Kidney Diseases
  • cholecystokinin
  • Cholecystokinin
  • Chromosomes
  6 Citations (Scopus)

• Genetic mapping of the thymoma susceptible locus, Tsr1, in BUF/Mna rats

  Oyabu, A., Higo, K., Ye, C., Amo, H., Saito, M., Yagyu, S., Morita, H., Maeda, K., Serikawa, T., Takahashi, M. & Matsuyama, M., 03-02-1999, In: Journal of the National Cancer Institute. 91, 3, p. 279-282 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• Genetic or pharmacological depletion of cannabinoid CB1 receptor protects against dopaminergic neurotoxicity induced by methamphetamine in mice

  Dang, D. K., Shin, E. J., Mai, A. T., Jang, C. G., Nah, S. Y., Jeong, J. H., Ledent, C., Yamamoto, T., Nabeshima, T., Onaivi, E. S. & Kim, H. C., 01-07-2017, In: Free Radical Biology and Medicine. 108, p. 204-224 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Cannabinoid Receptor CB1
  • Methamphetamine
  • Pharmacology
  • Oxidative stress
  • AM 251
  16 Citations (Scopus)

• Genetic overlap between antipsychotic response and susceptibility to schizophrenia

  Ikeda, M., Yoshimura, R., Hashimoto, R., Kondo, K., Saito, T., Shimasaki, A., Ohi, K., Tochigi, M., Kawamura, Y., Nishida, N., Miyagawa, T., Sasaki, T., Tokunaga, K., Kasai, K., Takeda, M., Nakamura, J., Ozaki, N. & Iwata, N., 01-02-2015, In: Journal of Clinical Psychopharmacology. 35, 1, p. 85-88 4 p.

  Research output: Contribution to journal › Letter › peer-review
  8 Citations (Scopus)

• Genetic polymorphism in the phenobarbital-responsive enhancer module of the UDP-glucuronosyltransferase 1A1 gene and irinotecan toxicity

  Kitagawa, C., Ando, M., Ando, Y., Sekido, Y., Wakai, K., Imaizumi, K., Shimokata, K. & Hasegawa, Y., 01-2005, In: Pharmacogenetics and genomics. 15, 1, p. 35-41 7 p.

  Research output: Contribution to journal › Article › peer-review

  • UGT1A1 enzyme
  • Irinotecan
  • Phenobarbital
  • Genetic Polymorphisms
  • Homozygote
  59 Citations (Scopus)

• Genetic polymorphism of interleukin-17A and -17F genes in gastric carcinogenesis

  Shibata, T., Tahara, T., Hirata, I. & Arisawa, T., 01-07-2009, In: Human Immunology. 70, 7, p. 547-551 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-17
  • Genetic Polymorphisms
  • Carcinogenesis
  • Stomach
  • Stomach Neoplasms
  117 Citations (Scopus)

• Genetic polymorphism of pri-microRNA 325, targeting SLC6A4 3′-UTR, is closely associated with the risk of functional dyspepsia in Japan

  Arisawa, T., Tahara, T., Fukuyama, T., Hayashi, R., Matsunaga, K., Hayashi, N., Nakamura, M., Toshikuni, N., Shiroeda, H. & Shibata, T., 01-10-2012, In: Journal of Gastroenterology. 47, 10, p. 1091-1098 8 p.

  Research output: Contribution to journal › Article › peer-review

  • 5' Untranslated Regions
  • Dyspepsia
  • Genetic Polymorphisms
  • 3' Untranslated Regions
  • MicroRNAs
  14 Citations (Scopus)

• Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function

  Chen, L., Takizawa, M., Chen, E., Schlessinger, A., Segenthelar, J., Choi, J. H., Sali, A., Kubo, M., Nakamura, S., Iwamoto, Y., Iwasaki, N. & Giacomini, K. M., 10-2010, In: Journal of Pharmacology and Experimental Therapeutics. 335, 1, p. 42-50 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Organic Cation Transporter 1
  • Genetic Polymorphisms
  • Metformin
  • Population
  • Green Fluorescent Proteins
  56 Citations (Scopus)

• Genetic polymorphisms in the 5-hydroxytryptamine type 3B receptor gene and paroxetine-induced nausea

  Tanaka, M., Kobayashi, D., Murakami, Y., Ozaki, N., Suzuki, T., Iwata, N., Haraguchi, K., Ieiri, I., Kinukawa, N., Hosoi, M., Ohtani, H., Sawada, Y. & Mine, K., 03-2008, In: International Journal of Neuropsychopharmacology. 11, 2, p. 261-267 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Paroxetine
  • Serotonin Receptors
  • Genetic Polymorphisms
  • Nausea
  • Genes
  51 Citations (Scopus)

• Genetic polymorphisms in the long noncoding RNA MIR2052HG offer a pharmacogenomic basis for the response of breast cancer patients to aromatase inhibitor therapy

  Ingle, J. N., Xie, F., Ellis, M. J., Goss, P. E., Shepherd, L. E., Chapman, J. A. W., Chen, B. E., Kubo, M., Furukawa, Y., Momozawa, Y., Stearns, V., Pritchard, K. I., Barman, P., Carlson, E. E., Goetz, M. P., Weinshilboum, R. M., Kalari, K. R. & Wang, L., 01-12-2016, In: Cancer Research. 76, 23, p. 7012-7023 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Aromatase Inhibitors
  • Long Noncoding RNA
  • Pharmacogenetics
  • Genetic Polymorphisms
  • Estrogen Receptors
  27 Citations (Scopus)

• Genetic polymorphisms in the promoter of the interferon gamma receptor 1 gene are associated with atopic cataracts

  Matsuda, A., Ebihara, N., Kumagai, N., Fukuda, K., Ebe, K., Hirano, K., Sotozono, C., Tei, M., Hasegawa, K., Shimizu, M., Tamari, M., Namba, K., Ohno, S., Mizuki, N., Ikezawa, Z., Shirakawa, T., Hamuro, J. & Kinoshita, S., 02-2007, In: Investigative Ophthalmology and Visual Science. 48, 2, p. 583-589 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • interferon gamma receptor
  • Genetic Polymorphisms
  • Atopic Dermatitis
  • Cataract
  • Eye
  18 Citations (Scopus)

• Genetic polymorphisms of CD14 and Toll-like receptor-2 (TLR2) in patients with ulcerative colitis

  Wang, F., Tahara, T., Arisawa, T., Shibata, T., Nakamura, M., Fujita, H., Iwata, M., Kamiya, Y., Nagasaka, M., Takahama, K., Watanabe, M., Hirata, I. & Nakano, H., 06-2007, In: Journal of Gastroenterology and Hepatology (Australia). 22, 6, p. 925-929 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Toll-Like Receptor 2
  • Genetic Polymorphisms
  • Ulcerative Colitis
  • Colitis
  • Steroids
  24 Citations (Scopus)

• Genetic polymorphisms of cyclooxygenase-1 (COX-1) are associated with functional dyspepsia in Japanese women

  Arisawa, T., Tahara, T., Shibata, T., Nagasaka, M., Nakamura, M., Kamiya, Y., Fujita, H., Yoshioka, D., Arima, Y., Okubo, M., Hirata, I. & Nakano, H., 01-07-2008, In: Journal of Women's Health. 17, 6, p. 1039-1043 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclooxygenase 1
  • Dyspepsia
  • Genetic Polymorphisms
  • Prostaglandins
  • Genes
  24 Citations (Scopus)

• Genetic polymorphisms of IL17A and pri-microRNA-938, targeting IL17A 3'-UTR, influence susceptibility to gastric cancer

  Arisawa, T., Tahara, T., Shiroeda, H., Matsue, Y., Minato, T., Nomura, T., Yamada, H., Hayashi, R., Saito, T., Matsunaga, K., Fukuyama, T., Hayashi, N., Otsuka, T., Fukumura, A., Nakamura, M. & Shibata, T., 01-07-2012, In: Human Immunology. 73, 7, p. 747-752 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetic Polymorphisms
  • 3' Untranslated Regions
  • Stomach Neoplasms
  • MicroRNAs
  • Single-Stranded Conformational Polymorphism
  60 Citations (Scopus)

• Genetic polymorphisms of MAFK, encoding a small Maf protein, are associated with susceptibility to ulcerative colitis in Japan

  Arisawa, T., Nakamura, M., Otsuka, T., Jing, W., Sakurai, N., Takano, H., Hayashi, T., Ota, M., Nomura, T., Hayashi, R., Shimasaki, T., Tahara, T. & Shibata, T., 07-08-2017, In: World Journal of Gastroenterology. 23, 29, p. 5364-5370 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Maf Transcription Factors
  • protein K
  • Genetic Polymorphisms
  • Ulcerative Colitis
  • Japan
  1 Citation (Scopus)

• Genetic polymorphisms of molecules associated with inflammation and immune response in Japanese subjects with functional dyspepsia

  Arisawa, T., Tahara, T., Shibata, T., Nagasaka, M., Nakamura, M., Kamiya, Y., Fujita, H., Yoshioka, D., Arima, Y., Okubo, M., Hirata, I. & Nakano, H., 01-11-2007, In: International Journal of Molecular Medicine. 20, 5, p. 717-723 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Dyspepsia
  • Interleukin-17
  • Genetic Polymorphisms
  • Inflammation
  • Helicobacter pylori
  50 Citations (Scopus)

• Genetic polymorphisms of molecules associated with innate immune responses, TRL2 and MBL2 genes in Japanese subjects with functional dyspepsia

  Tahara, T., Shibata, T., Wang, F., Yamashita, H., Hirata, I. & Arisawa, T., 11-2010, In: Journal of Clinical Biochemistry and Nutrition. 47, 3, p. 217-223 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Toll-Like Receptor 2
  • Polymorphism
  • Dyspepsia
  • Genetic Polymorphisms
  • Molecules
  16 Citations (Scopus)

• Genetic polymorphisms of SCN10A are associated with functional dyspepsia in Japanese subjects

  Arisawa, T., Tahara, T., Shiroeda, H., Minato, T., Matsue, Y., Saito, T., Fukuyama, T., Otsuka, T., Fukumura, A., Nakamura, M. & Shibata, T., 01-01-2013, In: Journal of Gastroenterology. 48, 1, p. 73-80 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dyspepsia
  • Genetic Polymorphisms
  • Unmyelinated Nerve Fibers
  • Homozygote
  • Alleles
  21 Citations (Scopus)

• Genetic polymorphisms of the adenosine triphosphate-binding cassette transporters (abcg2, abcb1) and gefitinib toxicity

  Tamura, M., Kondo, M., Horio, M., Ando, M., Saito, H., Yamamoto, M., Horio, Y. & Hasegawa, Y., 01-12-2012, In: Nagoya journal of medical science. 74, 1-2, p. 133-140 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Gefitinib
  • Genetic Polymorphisms
  • Adenosine Triphosphate
  • Exanthema
  • Alleles
  32 Citations (Scopus)

• Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids

  Park, H. W., Dahlin, A., Tse, S., Duan, Q. L., Schuemann, B., Martinez, F. D., Peters, S. P., Szefler, S. J., Lima, J. J., Kubo, M., Tamari, M. & Tantisira, K. G., 03-2014, In: Journal of Allergy and Clinical Immunology. 133, 3, p. 664-669.e5

  Research output: Contribution to journal › Article › peer-review

  • Adrenal Cortex Hormones
  • Asthma
  • Genome-Wide Association Study
  • Single Nucleotide Polymorphism
  • European Continental Ancestry Group
  50 Citations (Scopus)

• Genetic Predisposition to Ischemic Stroke: A Polygenic Risk Score

  Hachiya, T., Kamatani, Y., Takahashi, A., Hata, J., Furukawa, R., Shiwa, Y., Yamaji, T., Hara, M., Tanno, K., Ohmomo, H., Ono, K., Takashima, N., Matsuda, K., Wakai, K., Sawada, N., Iwasaki, M., Yamagishi, K., Ago, T., Ninomiya, T., Fukushima, A. & 21 others, Hozawa, A., Minegishi, N., Satoh, M., Endo, R., Sasaki, M., Sakata, K., Kobayashi, S., Ogasawara, K., Nakamura, M., Hitomi, J., Kita, Y., Tanaka, K., Iso, H., Kitazono, T., Kubo, M., Tanaka, H., Tsugane, S., Kiyohara, Y., Yamamoto, M., Sobue, K. & Shimizu, A., 01-02-2017, In: Stroke. 48, 2, p. 253-258 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetic Predisposition to Disease
  • Stroke
  • Datasets
  • Confidence Intervals
  • Risk Management
  32 Citations (Scopus)

• Genetic profiles of fluoroquinolone-resistant Escherichia coli isolates obtained from patients with cystitis: Phylogeny, virulence factors, PAIusp subtypes, and mutation patterns

  Takahashi, A., Muratani, T., Yasuda, M., Takahashi, S., Monden, K., Ishikawa, K., Kiyota, H., Arakawa, S., Matsumoto, T., Shima, H., Kurazono, H. & Yamamoto, S., 03-2009, In: Journal of clinical microbiology. 47, 3, p. 791-795 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genetic Profile
  • Cystitis
  • Fluoroquinolones
  • Virulence Factors
  • Escherichia coli
  28 Citations (Scopus)

• Genetic regulation of slowly progressing mild muscle atrophy in fast- twitch muscles of BUF/Mna rats

  Amo, H., Saito, M., Nagao, S., Yagiu, S., Takahashi, H., Morita, H., Morita, T. M. & Matsuyama, M., 1997, In: Muscle and Nerve. 20, 10, p. 1258-1263 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Inbred BUF Rats
  • Muscular Atrophy
  • Muscles
  • Dominant Genes
  • Oculomotor Muscles
  6 Citations (Scopus)

• Genetic risk factors of ischemic stroke identified by a genome-wide association study

  Kubo, M., 01-11-2008, In: Brain and Nerve. 60, 11, p. 1339-1346 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Stroke
  • protein kinase C eta
  • Single Nucleotide Polymorphism
  • Genes
  6 Citations (Scopus)

• Genetic risk for coronary artery disease in individuals with or without type 2 diabetes

  Yamada, Y., Ichihara, S., Izawa, H., Tanaka, M. & Yokota, M., 04-2004, In: Molecular Genetics and Metabolism. 81, 4, p. 282-290 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Medical problems
  • Genes
  • Coronary Artery Disease
  • Type 2 Diabetes Mellitus
  • Polymorphism
  33 Citations (Scopus)

• Genetic risk for restenosis after coronary balloon angioplasty

  Horibe, H., Yamada, Y., Ichihara, S., Watarai, M., Yanase, M., Takemoto, K., Shimizu, S., Izawa, H., Takatsu, F. & Yokota, M., 05-2004, In: Atherosclerosis. 174, 1, p. 181-187 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Coronary Balloon Angioplasty
  • Balloon Angioplasty
  • Genes
  • Coronary Vessels
  • NADH oxidase
  16 Citations (Scopus)

• Genetic risk score based on the prevalence of vertebral fracture in Japanese women with osteoporosis

  Zhou, H., Mori, S., Ishizaki, T., Takahashi, A., Matsuda, K., Koretsune, Y., Minami, S., Higashiyama, M., Imai, S., Yoshimori, K., Doita, M., Yamada, A., Nagayama, S., Kaneko, K., Asai, S., Shiono, M., Kubo, M. & Ito, H., 01-12-2016, In: Bone Reports. 5, p. 168-172 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Osteoporosis
  • Single Nucleotide Polymorphism
  • Alleles
  • Confidence Intervals
  • Genetic Models
  5 Citations (Scopus)

• Genetic risk variants of schizophrenia associated with left superior temporal gyrus volume

  Ohi, K., Hashimoto, R., Ikeda, M., Yamashita, F., Fukunaga, M., Nemoto, K., Ohnishi, T., Yamamori, H., Yasuda, Y., Fujimoto, M., Umeda-Yano, S., Watanabe, Y., Iwata, N., Weinberger, D. R. & Takeda, M., 09-2014, In: Cortex. 58, p. 23-26 4 p.

  Research output: Contribution to journal › Letter › peer-review
  14 Citations (Scopus)

• Genetics and reverse genetics of rotavirus

  Taniguchi, K. & Komoto, S., 08-2012, In: Current Opinion in Virology. 2, 4, p. 399-407 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Reverse Genetics
  • Rotavirus
  • Helper Viruses
  • Reoviridae
  • Genome
  13 Citations (Scopus)

• Genetic shifts in methicillin-resistant Staphylococcus aureus epidemic clones and toxin gene profiles in Japan: Comparative analysis among pre-epidemic, epidemic and post-epidemic phases

  Osaka, S., Okuzumi, K., Koide, S., Tamai, K., Sato, T., Tanimoto, K., Tomita, H., Suzuki, M., Nagano, Y., Shibayama, K., Arakawa, Y. & Nagano, N., 03-2018, In: Journal of Medical Microbiology. 67, 3, p. 392-399 8 p., 000687.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Methicillin-Resistant Staphylococcus aureus
  • Epidemics
  • Japan
  • Clone Cells
  • Genes
  5 Citations (Scopus)

• Genetics of rheumatoid arthritis contributes to biology and drug discovery

  Okada, Y., Wu, D., Trynka, G., Raj, T., Terao, C., Ikari, K., Kochi, Y., Ohmura, K., Suzuki, A., Yoshida, S., Graham, R. R., Manoharan, A., Ortmann, W., Bhangale, T., Denny, J. C., Carroll, R. J., Eyler, A. E., Greenberg, J. D., Kremer, J. M., Pappas, D. A. & 75 others, Jiang, L., Yin, J., Ye, L., Su, D. F., Yang, J., Xie, G., Keystone, E., Westra, H. J., Esko, T., Metspalu, A., Zhou, X., Gupta, N., Mirel, D., Stahl, E. A., Diogo, D., Cui, J., Liao, K., Guo, M. H., Myouzen, K., Kawaguchi, T., Coenen, M. J. H., Van Riel, P. L. C. M., Van De Laar, M. A. F. J., Guchelaar, H. J., Huizinga, T. W. J., Dieudé, P., Mariette, X., Bridges, S. L., Zhernakova, A., Toes, R. E. M., Tak, P. P., Miceli-Richard, C., Bang, S. Y., Lee, H. S., Martin, J., Gonzalez-Gay, M. A., Rodriguez-Rodriguez, L., Rantapää-Dahlqvist, S., Ärlestig, L., Choi, H. K., Kamatani, Y., Galan, P., Lathrop, M., Eyre, S., Bowes, J., Barton, A., De Vries, N., Moreland, L. W., Criswell, L. A., Karlson, E. W., Taniguchi, A., Yamada, R., Kubo, M., Liu, J. S., Bae, S. C., Worthington, J., Padyukov, L., Klareskog, L., Gregersen, P. K., Raychaudhuri, S., Stranger, B. E., De Jager, P. L., Franke, L., Visscher, P. M., Brown, M. A., Yamanaka, H., Mimori, T., Takahashi, A., Xu, H., Behrens, T. W., Siminovitch, K. A., Momohara, S., Matsuda, F., Yamamoto, K. & Plenge, R. M., 2014, In: Nature. 506, 7488, p. 376-381 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Drug Discovery
  • Rheumatoid Arthritis
  • Quantitative Trait Loci
  • Multifactorial Inheritance
  • Human Genetics
  994 Citations (Scopus)

• Genetic Spectrum of EYS-associated Retinal Disease in a Large Japanese Cohort: Identification of Disease-associated Variants with Relatively High Allele Frequency

  JEGC study group, 01-12-2020, In: Scientific reports. 10, 1, 5497.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retinal Diseases
  • Gene Frequency
  • Cone-Rod Dystrophies
  • Leber Congenital Amaurosis
  • Whole Exome Sequencing
  3 Citations (Scopus)

• Genetic studies of body mass index yield new insights for obesity biology

  Lifelines Cohort Study & ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium, 12-02-2015, In: Nature. 518, 7538, p. 197-206 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Body Mass Index
  • Obesity
  • Adipogenesis
  • Genome-Wide Association Study
  • Adiposity
  1769 Citations (Scopus)

• Genetic studies on substance dependence

  Ujiie, H., Inada, T., Harano, M., Komiyayama, T., Yamada, M., Sekine, Y., Sora, I., Iwata, N., Iyo, M. & Ozaki, N., 01-12-2004, In: Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. 106, 12, p. 1598-1603 6 p.

  Research output: Contribution to journal › Review article › peer-review
  3 Citations (Scopus)

• Genetic tests in clinical testing

  Takeda, M. & Funato, T., 10-12-2008, In: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 97, 12, p. 2920-2926 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Genetic variant of prodynorphin gene is risk factor for methamphetamine dependence

  Nomura, A., Ujike, H., Tanaka, Y., Otani, K., Morita, Y., Kishimoto, M., Morio, A., Harano, M., Inada, T., Yamada, M., Komiyama, T., Sekine, Y., Iwata, N., Sora, I., Iyo, M., Ozaki, N. & Kuroda, S., 29-05-2006, In: Neuroscience Letters. 400, 1-2, p. 158-162 5 p.

  Research output: Contribution to journal › Article › peer-review

  • preproenkephalin
  • Methamphetamine
  • Genes
  • Alleles
  • Substance-Related Disorders
  22 Citations (Scopus)

• Genetic variant of the p22PH0X component of NADPH oxidase C242T and the incidence of gastric cancer in Japan

  Tahara, T., Arisawa, T., Shibata, T., Nakamura, M., Wang, F., Yoshioka, D., Okubo, M., Maruyama, N., Kamano, T., Kamiya, Y., Nakamura, M., Fujita, H., Nagasaka, M., Iwata, M., Takahama, K., Watanabe, M., Yamashita, H., Nakano, H. & Hirata, I., 11-2008, In: Hepato-gastroenterology. 55, 88, p. 2273-2276 4 p.

  Research output: Contribution to journal › Article › peer-review

  • NADPH Oxidases
  • Stomach Neoplasms
  • Japan
  • Incidence
  • Genotype
  1 Citation (Scopus)

• Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema

  Pare, G., Kubo, M., Byrd, J. B., McCarty, C. A., Woodard-Grice, A., Teo, K. K., Anand, S. S., Zuvich, R. L., Bradford, Y., Ross, S., Nakamura, Y., Ritchie, M. & Brown, N. J., 09-2013, In: Pharmacogenetics and genomics. 23, 9, p. 470-478 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Angioedema
  • Angiotensin-Converting Enzyme Inhibitors
  • Telmisartan
  • Ramipril
  • MME
  47 Citations (Scopus)

• Genetic variants associated with uncontrolled blood pressure on thiazide diuretic/β-blocker combination therapy in the PEAR (Pharmacogenomic Evaluation Of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) trials

  Magvanjav, O., Gong, Y., McDonough, C. W., Chapman, A. B., Turner, S. T., Gums, J. G., Bailey, K. R., Boerwinkle, E., Beitelshees, A. L., Tanaka, T., Kubo, M., Pepine, C. J., Cooper-DeHoff, R. M. & Johnson, J. A., 01-11-2017, In: Journal of the American Heart Association. 6, 11, e006522.

  Research output: Contribution to journal › Article › peer-review

  • trandolapril
  • Sodium Chloride Symporter Inhibitors
  • Pharmacogenetics
  • Verapamil
  • Antihypertensive Agents
  3 Citations (Scopus)

• Genetic variants associated with warfarin dose in African-American individuals: A genome-wide association study

  Perera, M. A., Cavallari, L. H., Limdi, N. A., Gamazon, E. R., Konkashbaev, A., Daneshjou, R., Pluzhnikov, A., Crawford, D. C., Wang, J., Liu, N., Tatonetti, N., Bourgeois, S., Takahashi, H., Bradford, Y., Burkley, B. M., Desnick, R. J., Halperin, J. L., Khalifa, S. I., Langaee, T. Y., Lubitz, S. A. & 22 others, Nutescu, E. A., Oetjens, M., Shahin, M. H., Patel, S. R., Sagreiya, H., Tector, M., Weck, K. E., Rieder, M. J., Scott, S. A., Wu, A. H. B., Burmester, J. K., Wadelius, M., Deloukas, P., Wagner, M. J., Mushiroda, T., Kubo, M., Roden, D. M., Cox, N. J., Altman, R. B., Klein, T. E., Nakamura, Y. & Johnson, J. A., 2013, In: The Lancet. 382, 9894, p. 790-796 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Warfarin
  • African Americans
  • Cytochrome P-450 CYP2C9
  • Pharmacogenetics
  157 Citations (Scopus)

• Genetic variants in CPA6 and PRPF31 are associated with variation in response to metformin in individuals with type 2 diabetes

  Rotroff, D. M., Yee, S. W., Zhou, K., Marvel, S. W., Shah, H. S., Jack, J. R., Havener, T. M., Hedderson, M. M., Kubo, M., Herman, M. A., Gao, H., Mychaleckyi, J. C., McLeod, H. L., Doria, A., Giacomini, K. M., Pearson, E. R., Wagner, M. J., Buse, J. B. & Motsinger-Reif, A. A., 07-2018, In: Diabetes. 67, 7, p. 1428-1440 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Metformin
  • Type 2 Diabetes Mellitus
  • Glucose
  • Feeding Behavior
  • Knockout Mice
  8 Citations (Scopus)

• Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis

  Kou, I., Takahashi, Y., Johnson, T. A., Takahashi, A., Guo, L., Dai, J., Qiu, X., Sharma, S., Takimoto, A., Ogura, Y., Jiang, H., Yan, H., Kono, K., Kawakami, N., Uno, K., Ito, M., Minami, S., Yanagida, H., Taneichi, H., Hosono, N. & 21 others, Tsuji, T., Suzuki, T., Sudo, H., Kotani, T., Yonezawa, I., Londono, D., Gordon, D., Herring, J. A., Watanabe, K., Chiba, K., Kamatani, N., Jiang, Q., Hiraki, Y., Kubo, M., Toyama, Y., Tsunoda, T., Wise, C. A., Qiu, Y., Shukunami, C., Matsumoto, M. & Ikegawa, S., 06-2013, In: Nature Genetics. 45, 6, p. 676-679 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Scoliosis
  • G-Protein-Coupled Receptors
  • Genome-Wide Association Study
  • Single Nucleotide Polymorphism
  • Chromosomes
  128 Citations (Scopus)

• Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin

  Goswami, S., Yee, S. W., Stocker, S., Mosley, J. D., Kubo, M., Castro, R., Mefford, J. A., Wen, C., Liang, X., Witte, J., Brett, C., Maeda, S., Simpson, M. D., Hedderson, M. M., Davis, R. L., Roden, D. M., Giacomini, K. M. & Savic, R. M., 09-2014, In: Clinical Pharmacology and Therapeutics. 96, 3, p. 370-379 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Metformin
  • Pharmacokinetics
  • Transcription Factors
  • Hepatocyte Nuclear Factor 4
  • Sp1 Transcription Factor
  45 Citations (Scopus)