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• Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese

  Horikawa, Y., Oda, N., Yu, L., Imamura, S., Fujiwara, K., Makino, M., Seino, Y., Itoh, M. & Takeda, J., 01-01-2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 1, p. 244-247 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • calpain 10
  • Medical problems
  • Genetic Variation
  • Genes
  • Type 2 Diabetes Mellitus
  56 Citations (Scopus)

• Gene transfer of dominant negative Rho kinase suppresses neointimal formation after balloon injury in pigs

  Eto, Y., Shimokawa, H., Hiroki, J., Morishige, K., Kandabashi, T., Matsumoto, Y., Amano, M., Hoshijima, M., Kaibuchi, K. & Takeshita, A., 06-2000, In: American Journal of Physiology - Heart and Circulatory Physiology. 278, 6 47-6, p. H1744-H1750

  Research output: Contribution to journal › Article › peer-review

  • Dominant Genes
  • rho-Associated Kinases
  • Swine
  • Wounds and Injuries
  • Galactosidases
  88 Citations (Scopus)

• Gene transfer of high-mobility group box 1 box-A domain in a rat acute liver failure model

  Tanaka, M., Shinoda, M., Takayanagi, A., Oshima, G., Nishiyama, R., Fukuda, K., Yagi, H., Hayashida, T., Masugi, Y., Suda, K., Yamada, S., Miyasho, T., Hibi, T., Abe, Y., Kitago, M., Obara, H., Itano, O., Takeuchi, H., Sakamoto, M., Tanabe, M. & 2 others, Maruyama, I. & Kitagawa, Y., 01-04-2015, In: Journal of Surgical Research. 194, 2, p. 571-580 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Acute Liver Failure
  • HeLa Cells
  • Genes
  • Proteins
  • Liver
  4 Citations (Scopus)

• Gene variants in PPARD and PPARGC1A are associated with timing of natural menopause in the general Japanese population

  Uemura, H., Hiyoshi, M., Arisawa, K., Yamaguchi, M., Naito, M., Kawai, S., Hamajima, N., Matsuo, K., Taguchi, N., Takashima, N., Suzuki, S., Hirasada, K., Mikami, H., Ohnaka, K., Yoshikawa, A., Kubo, M. & Tanaka, H., 04-2012, In: Maturitas. 71, 4, p. 369-375 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Menopause
  • Genes
  • Hazards
  • Health risks
  • Polymorphism
  6 Citations (Scopus)

• Gene-wide association study between the methylenetetrahydrofolate reductase gene (MTHFR) and schizophrenia in the Japanese population, with an updated meta-analysis on currently available data

  Yoshimi, A., Aleksic, B., Kawamura, Y., Takahashi, N., Yamada, S., Usui, H., Saito, S., Ito, Y., Iwata, N., Inada, T., Noda, Y., Yamada, K. & Ozaki, N., 12-2010, In: Schizophrenia Research. 124, 1-3, p. 216-222 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Methylenetetrahydrofolate Reductase (NADPH2)
  • Schizophrenia
  • Meta-Analysis
  • Genes
  • Population
  30 Citations (Scopus)

• Genistein, an isoflavone included in soy, inhibits thrombotic vessel occlusion in the mouse femoral artery and in vitro platelet aggregation

  Kondo, K., Suzuki, Y., Ikeda, Y. & Umemura, K., 22-11-2002, In: European Journal of Pharmacology. 455, 1, p. 53-57 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Isoflavones
  • Genistein
  • Femoral Artery
  • Platelet Aggregation
  • In Vitro Techniques
  53 Citations (Scopus)

• Genistein inhibits Ca²⁺ influx by extracellular ATP in PC12 pheochromocytoma cells

  Kozawa, O., Shinoda, J. & Suzuki, A., 1995, In: Hormone and Metabolic Research. 27, 6, p. 272-274 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Genistein
  • PC12 Cells
  • Pheochromocytoma
  • Adenosine Triphosphate
  • Protein-Tyrosine Kinases
  2 Citations (Scopus)

• Genistein inhibits potentiation by wortmannin of protein kinase C-activated phospholipase D in osteoblast-like cells

  Kozawa, O., Suzuki, A., Shinoda, J. & Oiso, Y., 03-1995, In: Cellular Signalling. 7, 3, p. 219-223 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Phospholipase D
  • Wortmannin
  • Genistein
  • Osteoblasts
  • Protein Kinase C
  6 Citations (Scopus)

• Genital abnormalities in Pallister-Hall syndrome: Report of two patients and review of the literature

  Narumi, Y., Kosho, T., Tsuruta, G., Shiohara, M., Shimazaki, E., Mori, T., Shimizu, A., Igawa, Y., Nishizawa, S., Takagi, K., Kawamura, R., Wakui, K. & Fukushima, Y., 12-2010, In: American Journal of Medical Genetics, Part A. 152 A, 12, p. 3143-3147 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Pallister-Hall Syndrome
  • Genitalia
  • Penis agenesis
  • Scrotum
  • Mutation
  18 Citations (Scopus)

• Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

  Lifelines Cohort Study, 01-12-2018, In: Nature communications. 9, 1, 4455.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hormones
  • genome
  • Thyroid Hormones
  • Genes
  • Thyroid Diseases
  32 Citations (Scopus)

• Genome wide analysis of drug-induced torsades de pointes: Lack of common variants with large effect sizes

  Behr, E. R., Ritchie, M. D., Tanaka, T., Kääb, S., Crawford, D. C., Nicoletti, P., Floratos, A., Sinner, M. F., Kannankeril, P. J., Wilde, A. A. M., Bezzina, C. R., Schulze-Bahr, E., Zumhagen, S., Guicheney, P., Bishopric, N. H., Marshall, V., Shakir, S., Dalageorgou, C., Bevan, S., Jamshidi, Y. & 14 others, Bastiaenen, R., Myerburg, R. J., Schott, J. J., Camm, A. J., Steinbeck, G., Norris, K., Altman, R. B., Tatonetti, N. P., Jeffery, S., Kubo, M., Nakamura, Y., Shen, Y., George, A. L. & Roden, D. M., 06-11-2013, In: PloS one. 8, 11, e78511.

  Research output: Contribution to journal › Article › peer-review

  • Torsades de Pointes
  • Genes
  • Polymorphism
  • Genome
  • drugs
  40 Citations (Scopus)

• Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points—Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC)

  for the ICPC Investigators, 04-2018, In: American Heart Journal. 198, p. 152-159 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Clopidogrel
  • Pharmacogenetics
  • Genome
  • Genes
  • Blood Platelets
  16 Citations (Scopus)

• Genome-wide array-based comparative genomic hybridization of diffuse large B-cell lymphoma: Comparison between CD5-positive and CD5-negative cases

  Tagawa, H., Tsuzuki, S., Suzuki, R., Karnan, S., Ota, A., Kameoka, Y., Suguro, M., Matsuo, K., Yamaguchi, M., Okamoto, M., Morishima, Y., Nakamura, S. & Seto, M., 01-09-2004, In: Cancer Research. 64, 17, p. 5948-5955 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Comparative Genomic Hybridization
  • Lymphoma, Large B-Cell, Diffuse
  • Genome
  • Non-Hodgkin's Lymphoma
  62 Citations (Scopus)

• Genomewide assessment of mycobacterium tuberculosis conditionally essential metabolic pathways

  Minato, Y., Gohl, D. M., Thiede, J. M., Chacón, J. M., Harcombe, W. R., Maruyama, F. & Baughn, A. D., 2019, In: mSystems. 4, 4, e00070-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Metabolic Networks and Pathways
  • Tuberculosis
  • tuberculosis
  • Pathway
  • Mycobacterium tuberculosis
  8 Citations (Scopus)

• Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

  Köttgen, A., Albrecht, E., Teumer, A., Vitart, V., Krumsiek, J., Hundertmark, C., Pistis, G., Ruggiero, D., O'Seaghdha, C. M., Haller, T., Yang, Q., Tanaka, T., Johnson, A. D., Kutalik, Z., Smith, A. V., Shi, J., Struchalin, M., Middelberg, R. P. S., Brown, M. J., Gaffo, A. L. & 205 others, Pirastu, N., Li, G., Hayward, C., Zemunik, T., Huffman, J., Yengo, L., Zhao, J. H., Demirkan, A., Feitosa, M. F., Liu, X., Malerba, G., Lopez, L. M., Van Der Harst, P., Li, X., Kleber, M. E., Hicks, A. A., Nolte, I. M., Johansson, A., Murgia, F., Wild, S. H., Bakker, S. J. L., Peden, J. F., Dehghan, A., Steri, M., Tenesa, A., Lagou, V., Salo, P., Mangino, M., Rose, L. M., Lehtimäki, T., Woodward, O. M., Okada, Y., Tin, A., Müller, C., Oldmeadow, C., Putku, M., Czamara, D., Kraft, P., Frogheri, L., Thun, G. A., Grotevendt, A., Gislason, G. K., Harris, T. B., Launer, L. J., McArdle, P., Shuldiner, A. R., Boerwinkle, E., Coresh, J., Schmidt, H., Schallert, M., Martin, N. G., Montgomery, G. W., Kubo, M., Nakamura, Y., Tanaka, T., Munroe, P. B., Samani, N. J., Jacobs, D. R., Liu, K., D'Adamo, P., Ulivi, S., Rotter, J. I., Psaty, B. M., Vollenweider, P., Waeber, G., Campbell, S., Devuyst, O., Navarro, P., Kolcic, I., Hastie, N., Balkau, B., Froguel, P., Esko, T., Salumets, A., Khaw, K. T., Langenberg, C., Wareham, N. J., Isaacs, A., Kraja, A., Zhang, Q., Wild, P. S., Scott, R. J., Holliday, E. G., Org, E., Viigimaa, M., Bandinelli, S., Metter, J. E., Lupo, A., Trabetti, E., Sorice, R., Döring, A., Lattka, E., Strauch, K., Theis, F., Waldenberger, M., Wichmann, H. E., Davies, G., Gow, A. J., Bruinenberg, M., Stolk, R. P., Kooner, J. S., Zhang, W., Winkelmann, B. R., Boehm, B. O., Lucae, S., Penninx, B. W., Smit, J. H., Curhan, G., Mudgal, P., Plenge, R. M., Portas, L., Persico, I., Kirin, M., Wilson, J. F., Leach, I. M., Van Gilst, W. H., Goel, A., Ongen, H., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Imboden, M., Von Eckardstein, A., Cucca, F., Nagaraja, R., Piras, M. G., Nauck, M., Schurmann, C., Budde, K., Ernst, F., Farrington, S. M., Theodoratou, E., Prokopenko, I., Stumvoll, M., Jula, A., Perola, M., Salomaa, V., Shin, S. Y., Spector, T. D., Sala, C., Ridker, P. M., Kähönen, M., Viikari, J., Hengstenberg, C., Nelson, C. P., Meschia, J. F., Nalls, M. A., Sharma, P., Singleton, A. B., Kamatani, N., Zeller, T., Burnier, M., Attia, J., Laan, M., Klopp, N., Hillege, H. L., Kloiber, S., Choi, H., Pirastu, M., Tore, S., Probst-Hensch, N. M., Völzke, H., Gudnason, V., Parsa, A., Schmidt, R., Whitfield, J. B., Fornage, M., Gasparini, P., Siscovick, D. S., Polašek, O., Campbell, H., Rudan, I., Bouatia-Naji, N., Metspalu, A., Loos, R. J. F., Van Duijn, C. M., Borecki, I. B., Ferrucci, L., Gambaro, G., Deary, I. J., Wolffenbuttel, B. H. R., Chambers, J. C., März, W., Pramstaller, P. P., Snieder, H., Gyllensten, U., Wright, A. F., Navis, G., Watkins, H., Witteman, J. C. M., Sanna, S., Schipf, S., Dunlop, M. G., Tönjes, A., Ripatti, S., Soranzo, N., Toniolo, D., Chasman, D. I., Raitakari, O., Kao, W. H. L., Ciullo, M., Fox, C. S., Caulfield, M., Bochud, M. & Gieger, C., 01-02-2013, In: Nature Genetics. 45, 2, p. 145-154 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Uric Acid
  • Gout
  • Serum
  • Inhibins
  419 Citations (Scopus)

• Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene

  Himes, B. E., Jiang, X., Hu, R., Wu, A. C., Lasky-Su, J. A., Klanderman, B. J., Ziniti, J., Senter-Sylvia, J., Lima, J. J., Irvin, C. G., Peters, S. P., Meyers, D. A., Bleecker, E. R., Kubo, M., Tamari, M., Nakamura, Y., Szefler, S. J., Lemanske, R. F., Zeiger, R. S., Strunk, R. C. & 14 others, Martinez, F. D., Hanrahan, J. P., Koppelman, G. H., Postma, D. S., Nieuwenhuis, M. A. E., Vonk, J. M., Panettieri, R. A., Markezich, A., Israel, E., Carey, V. J., Tantisira, K. G., Litonjua, A. A., Lu, Q. & Weiss, S. T., 07-2012, In: PLoS Genetics. 8, 7, e1002824.

  Research output: Contribution to journal › Article › peer-review

  • bronchodilators
  • genome-wide association study
  • asthma
  • Bronchodilator Agents
  • Genome-Wide Association Study
  75 Citations (Scopus)

• Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1

  Cai, Q., Zhang, B., Sung, H., Low, S. K., Kweon, S. S., Lu, W., Shi, J., Long, J., Wen, W., Choi, J. Y., Noh, D. Y., Shen, C. Y., Matsuo, K., Teo, S. H., Kim, M. K., Khoo, U. S., Iwasaki, M., Hartman, M., Takahashi, A., Ashikawa, K. & 31 others, Matsuda, K., Shin, M. H., Park, M. H., Zheng, Y., Xiang, Y. B., Ji, B. T., Park, S. K., Wu, P. E., Hsiung, C. N., Ito, H., Kasuga, Y., Kang, P., Mariapun, S., Ahn, S. H., Kang, H. S., Chan, K. Y. K., Man, E. P. S., Iwata, H., Tsugane, S., Miao, H., Liao, J., Nakamura, Y., Kubo, M., Delahanty, R. J., Zhang, Y., Li, B., Li, C., Gao, Y. T., Shu, X. O., Kang, D. & Zheng, W., 08-2014, In: Nature Genetics. 46, 8, p. 886-890 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Breast Neoplasms
  • Introns
  • Genetic Loci
  • Genes
  94 Citations (Scopus)

• Genome-wide association analysis of common genetic variants of resistant hypertension

  on behalf of eMERGE network, 01-06-2019, In: Pharmacogenomics Journal. 19, 3, p. 295-304 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Hypertension
  • Odds Ratio
  • Hispanic Americans
  • trandolapril
  2 Citations (Scopus)

• Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia

  Kikuchi, M., Miura, K., Morita, K., Yamamori, H., Fujimoto, M., Ikeda, M., Yasuda, Y., Nakaya, A. & Hashimoto, R., 01-12-2018, In: Scientific reports. 8, 1, 12347.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Eye Movements
  • Single Nucleotide Polymorphism
  • Schizophrenia
  • Quantitative Trait Loci
  3 Citations (Scopus)

• Genome-wide association analysis of red blood cell traits in African Americans: The cogent network

  Chen, Z., Tang, H., Qayyum, R., Schick, U. M., Nalls, M. A., Handsaker, R., Li, J., Lu, Y., Yanek, L. R., Keating, B., Meng, Y., Van Rooij, F. J. A., Okada, Y., Kubo, M., Rasmussen-Torvik, L., Keller, M. F., Lange, L., Evans, M., Bottinger, E. P., Linderman, M. D. & 16 others, Ruderfer, D. M., Hakonarson, H., Papanicolaou, G., Zonderman, A. B., Gottesman, O., Thomson, C., Ziv, E., Singleton, A. B., Loos, R. J. F., Sleiman, P. M. A., Ganesh, S., McCarroll, S., Becker, D. M., Wilson, J. G., Lettre, G. & Reiner, A. P., 06-2013, In: Human molecular genetics. 22, 12, p. 2529-2538 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • African Americans
  • Erythrocytes
  • Erythrocyte Indices
  • Hemoglobins
  37 Citations (Scopus)

• Genome-Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol

  Brackman, D. J., Yee, S. W., Enogieru, O. J., Shaffer, C., Ranatunga, D., Denny, J. C., Wei, W. Q., Kamatani, Y., Kubo, M., Roden, D. M., Jorgenson, E. & Giacomini, K. M., 01-01-2019, In: Clinical Pharmacology and Therapeutics. 106, 3, p. 623-631 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Allopurinol
  • Genome-Wide Association Study
  • Pharmacology
  • Oxypurinol
  • Uric Acid
  5 Citations (Scopus)

• Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity

  Petros, Z., Lee, M. T. M., Takahashi, A., Zhang, Y., Yimer, G., Habtewold, A., Amogne, W., Aderaye, G., Schuppe-Koistinen, I., Mushiroda, T., Makonnen, E., Kubo, M. & Aklillu, E., 26-09-2016, In: BMC Genomics. 17, 1, 755.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Tuberculosis
  • Single Nucleotide Polymorphism
  • Chemical and Drug Induced Liver Injury
  • Liver
  17 Citations (Scopus)

• Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs

  Petros, Z., Lee, M. T. M., Takahashi, A., Zhang, Y., Yimer, G., Habtewold, A., Schuppe-Koistinen, I., Mushiroda, T., Makonnen, E., Kubo, M. & Aklillu, E., 04-2017, In: OMICS A Journal of Integrative Biology. 21, 4, p. 207-216 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Genes
  • Tuberculosis
  • Pharmaceutical Preparations
  • Polymorphism
  7 Citations (Scopus)

• Genome-wide association for methamphetamine dependence: Convergent results from 2 samples

  Uhl, G. R., Drgon, T., Liu, Q. R., Johnson, C., Walther, D., Komiyama, T., Harano, M., Sekine, Y., Inada, T., Ozaki, N., Iyo, M., Iwata, N., Yamada, M., Sora, I., Chen, C. K., Liu, H. C., Ujike, H. & Lin, S. K., 03-2008, In: Archives of General Psychiatry. 65, 3, p. 345-385 41 p.

  Research output: Contribution to journal › Article › peer-review

  • Methamphetamine
  • Genome
  • Gene
  • Genes
  • Polymorphism
  109 Citations (Scopus)

• Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors

  Ingle, J. N., Schaid, D. J., Goss, P. E., Liu, M., Mushiroda, T., Chapman, J. A. W., Kubo, M., Jenkins, G. D., Batzler, A., Shepherd, L., Pater, J., Wang, L., Ellis, M. J., Stearns, V., Rohrer, D. C., Goetz, M. P., Pritchard, K. I., Flockhart, D. A., Nakamura, Y. & Weinshilboum, R. M., 01-11-2010, In: Journal of Clinical Oncology. 28, 31, p. 4674-4682 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Aromatase Inhibitors
  • Single Nucleotide Polymorphism
  • Genome
  • T-Cell Leukemia
  • Genome-Wide Association Study
  154 Citations (Scopus)

• Genome-wide association studies identify polygenic effects for completed suicide in the Japanese population

  Otsuka, I., Akiyama, M., Shirakawa, O., Okazaki, S., Momozawa, Y., Kamatani, Y., Izumi, T., Numata, S., Takahashi, M., Boku, S., Sora, I., Yamamoto, K., Ueno, Y., Toda, T., Kubo, M. & Hishimoto, A., 01-11-2019, In: Neuropsychopharmacology. 44, 12, p. 2119-2124 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Suicide
  • Population
  • Single Nucleotide Polymorphism
  • Datasets
  7 Citations (Scopus)

• Genomewide Association Studies in Pharmacogenomics: Meeting Report of the NIH Pharmacogenomics Research Network-RIKEN (PGRN-RIKEN) Collaboration

  Yee, S. W., Momozawa, Y., Kamatani, Y., Tyndale, R. F., Weinshilboum, R. M., Ratain, M. J., Giacomini, K. M. & Kubo, M., 01-11-2016, In: Clinical Pharmacology and Therapeutics. p. 423-426 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacogenomic Testing
  • Pharmacogenetics
  • Phenotype
  • Pharmaceutical Preparations
  4 Citations (Scopus)

• Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

  Imamura, M., Takahashi, A., Yamauchi, T., Hara, K., Yasuda, K., Grarup, N., Zhao, W., Wang, X., Huerta-Chagoya, A., Hu, C., Moon, S., Long, J., Kwak, S. H., Rasheed, A., Saxena, R., Ma, R. C. W., Okada, Y., Iwata, M., Hosoe, J., Shojima, N. & 43 others, Iwasaki, M., Fujita, H., Suzuki, K., Danesh, J., Jørgensen, T., Jørgensen, M. E., Witte, D. R., Brandslund, I., Christensen, C., Hansen, T., Mercader, J. M., Flannick, J., Moreno-Macías, H., Burtt, N. P., Zhang, R., Kim, Y. J., Zheng, W., Singh, J. R., Tam, C. H. T., Hirose, H., Maegawa, H., Ito, C., Kaku, K., Watada, H., Tanaka, Y., Tobe, K., Kawamori, R., Kubo, M., Cho, Y. S., Chan, J. C. N., Sanghera, D., Frossard, P., Park, K. S., Shu, X. O., Kim, B. J., Florez, J. C., Tusié-Luna, T., Jia, W., Tai, E. S., Pedersen, O., Saleheen, D., Maeda, S. & Kadowaki, T., 28-01-2016, In: Nature communications. 7, 10531.

  Research output: Contribution to journal › Article › peer-review

  • genome
  • loci
  • Medical problems
  • Genome-Wide Association Study
  • Genes
  81 Citations (Scopus)

• Genome-wide association studies of bipolar disorder: A systematic review of recent findings and their clinical implications

  Ikeda, M., Saito, T., Kondo, K. & Iwata, N., 01-02-2018, In: Psychiatry and clinical neurosciences. 72, 2, p. 52-63 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Genome-Wide Association Study
  • Bipolar Disorder
  • Systematic Reviews
  • Single Nucleotide Polymorphism
  • Statistics
  28 Citations (Scopus)

• Genome-wide association studies of drug response and toxicity: An opportunity for genome medicine

  Giacomini, K. M., Yee, S. W., Mushiroda, T., Weinshilboum, R. M., Ratain, M. J. & Kubo, M., 29-12-2016, In: Nature Reviews Drug Discovery. 16, 1, p. 1 1 p.

  Research output: Contribution to journal › Letter › peer-review
  39 Citations (Scopus)

• Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis

  Mahasirimongkol, S., Yanai, H., Mushiroda, T., Promphittayarat, W., Wattanapokayakit, S., Phromjai, J., Yuliwulandari, R., Wichukchinda, N., Yowang, A., Yamada, N., Kantipong, P., Takahashi, A., Kubo, M., Sawanpanyalert, P., Kamatani, N., Nakamura, Y. & Tokunaga, K., 06-2012, In: Journal of Human Genetics. 57, 6, p. 363-367 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Genome-Wide Association Study
  • Tuberculosis
  • Meta-Analysis
  • Single Nucleotide Polymorphism
  • Datasets
  74 Citations (Scopus)

• Genome-wide association study: A useful tool to identify common genetic variants associated with drug toxicity and efficacy in cancer pharmacogenomics

  Low, S. K., Takahashi, A., Mushiroda, T. & Kubo, M., 15-05-2014, In: Clinical Cancer Research. 20, 10, p. 2541-2552 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacogenetics
  • Genome-Wide Association Study
  • Drug-Related Side Effects and Adverse Reactions
  • Neoplasms
  • Genetic Variation
  35 Citations (Scopus)

• Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13.1

  Yodsurang, V., Tang, Y., Takahashi, Y., Tanikawa, C., Kamatani, Y., Takahashi, A., Momozawa, Y., Fuse, N., Sugawara, J., Shimizu, A., Fukushima, A., Hishida, A., Furusyo, N., Naito, M., Wakai, K., Yamaji, T., Sawadai, N., Iwasaki, M., Tsugane, S., Hirata, M. & 3 others, Murakami, Y., Kubo, M. & Matsuda, K., 12-2018, In: PloS one. 13, 12, e0209096.

  Research output: Contribution to journal › Article › peer-review

  • ovarian neoplasms
  • genome-wide association study
  • Genome-Wide Association Study
  • Ovarian Neoplasms
  • Genes
  1 Citation (Scopus)

• Genome-wide association study detected novel susceptibility genes for schizophrenia and shared trans-populations/diseases genetic effect

  Ikeda, M., Takahashi, A., Kamatani, Y., Momozawa, Y., Saito, T., Kondo, K., Shimasaki, A., Kawase, K., Sakusabe, T., Iwayama, Y., Toyota, T., Wakuda, T., Kikuchi, M., Kanahara, N., Yamamori, H., Yasuda, Y., Watanabe, Y., Hoya, S., Aleksic, B., Kushima, I. & 12 others, Arai, H., Takaki, M., Hattori, K., Kunugi, H., Okahisa, Y., Ohnuma, T., Ozaki, N., Someya, T., Hashimoto, R., Yoshikawa, T., Kubo, M. & Iwata, N., 18-06-2019, In: Schizophrenia Bulletin. 45, 4, p. 824-834 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Population Genetics
  • Genome-Wide Association Study
  • Schizophrenia
  • Genes
  • Bipolar Disorder
  23 Citations (Scopus)

• Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus

  Okada, Y., Takahashi, A., Ohmiya, H., Kumasaka, N., Kamatani, Y., Hosono, N., Tsunoda, T., Matsuda, K., Tanaka, T., Kubo, M., Nakamura, Y., Yamamoto, K. & Kamatani, N., 03-2011, In: Human molecular genetics. 20, 6, p. 1224-1231 8 p., ddq551.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • C-Reactive Protein
  • Interleukin-6
  • Blood Proteins
  • Erythrocyte Indices
  64 Citations (Scopus)

• Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA

  Low, S. K., Takahashi, A., Cha, P. C., Zembutsu, H., Kamatani, N., Kubo, M. & Nakamura, Y., 05-2012, In: Human molecular genetics. 21, 9, p. 2102-2110 9 p., dds020.

  Research output: Contribution to journal › Article › peer-review

  • Intracranial Aneurysm
  • Genome-Wide Association Study
  • Population
  • Subarachnoid Hemorrhage
  • Single Nucleotide Polymorphism
  74 Citations (Scopus)

• Genome-wide association study for pollinosis identified two novel loci in interleukin (IL)-1B in a Japanese population

  Fujii, R., Hishida, A., Wu, M. C., Kondo, T., Hattori, Y., Naito, M., Endoh, K., Nakatochi, M., Hamajima, N., Kubo, M., Kuriki, K. & Wakai, K., 01-02-2018, In: Nagoya journal of medical science. 80, 1, p. 109-120 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Seasonal Allergic Rhinitis
  • Interleukins
  • Genome-Wide Association Study
  • Single Nucleotide Polymorphism
  • Population
  1 Citation (Scopus)

• Genome-wide association study for white coat effect in Japanese middle-aged to elderly people: The HOMED-BP study

  Ogata, S., Kamide, K., Asayama, K., Tabara, Y., Kawaguchi, T., Satoh, M., Katsuya, T., Sugimoto, K., Hirose, T., Inoue, R., Hara, A., Obara, T., Kikuya, M., Metoki, H., Matsuda, F., Staessen, J. A., Ohkubo, T., Rakugi, H. & Imai, Y., 19-05-2018, In: Clinical and Experimental Hypertension. 40, 4, p. 363-369 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Elderly
  • Blood Pressure
  • Single Nucleotide Polymorphism
  • Genome
  2 Citations (Scopus)

• Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population

  Matsuda, K., Takahashi, A., Middlebrooks, C. D., Obara, W., Nasu, Y., Inoue, K., Tamura, K., Yamasaki, I., Naya, Y., Tanikawa, C., Cui, R., Figueroa, J. D., Silverman, D. T., Rothman, N., Namiki, M., Tomita, Y., Nishiyama, H., Kohri, K., Deguchi, T., Nakagawa, M. & 8 others, Yokoyama, M., Miki, T., Kumon, H., Fujioka, T., Prokunina-Olsson, L., Kubo, M., Nakamura, Y. & Shuin, T., 15-02-2015, In: Human molecular genetics. 24, 4, p. 1177-1184 8 p., ddu512.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Urinary Bladder Neoplasms
  • Single Nucleotide Polymorphism
  • Population
  • Odds Ratio
  24 Citations (Scopus)

• Genome-wide association study identifies 112 new loci for body mass index in the Japanese population

  Akiyama, M., Okada, Y., Kanai, M., Takahashi, A., Momozawa, Y., Ikeda, M., Iwata, N., Ikegawa, S., Hirata, M., Matsuda, K., Iwasaki, M., Yamaji, T., Sawada, N., Hachiya, T., Tanno, K., Shimizu, A., Hozawa, A., Minegishi, N., Tsugane, S., Yamamoto, M. & 2 others, Kubo, M. & Kamatani, Y., 01-10-2017, In: Nature Genetics. 49, 10, p. 1458-1467 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Body Mass Index
  • Obesity
  • Population
  • Lymphocyte Count
  139 Citations (Scopus)

• Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese

  Kou, I., Otomo, N., Takeda, K., Momozawa, Y., Lu, H. F., Kubo, M., Kamatani, Y., Ogura, Y., Takahashi, Y., Nakajima, M., Minami, S., Uno, K., Kawakami, N., Ito, M., Yonezawa, I., Watanabe, K., Kaito, T., Yanagida, H., Taneichi, H., Harimaya, K. & 27 others, Taniguchi, Y., Shigematsu, H., Iida, T., Demura, S., Sugawara, R., Fujita, N., Yagi, M., Okada, E., Hosogane, N., Kono, K., Nakamura, M., Chiba, K., Kotani, T., Sakuma, T., Akazawa, T., Suzuki, T., Nishida, K., Kakutani, K., Tsuji, T., Sudo, H., Iwata, A., Sato, T., Inami, S., Matsumoto, M., Terao, C., Watanabe, K. & Ikegawa, S., 01-12-2019, In: Nature communications. 10, 1, 3685.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • genome
  • loci
  • Scoliosis
  • Genome-Wide Association Study
  • Genes
  5 Citations (Scopus)

• Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians

  Zhang, B., Jia, W. H., Matsuo, K., Shin, A., Xiang, Y. B., Matsuda, K., Jee, S. H., Kim, D. H., Cheah, P. Y., Ren, Z., Cai, Q., Long, J., Shi, J., Wen, W., Yang, G., Ji, B. T., Pan, Z. Z., Matsuda, F., Gao, Y. T., Oh, J. H. & 13 others, Ahn, Y. O., Kubo, M., Thean, L. F., Park, E. J., Li, H. L., Park, J. W., Jo, J., Jeong, J. Y., Hosono, S., Nakamura, Y., Shu, X. O., Zeng, Y. X. & Zheng, W., 15-08-2014, In: International Journal of Cancer. 135, 4, p. 948-955 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Colorectal Neoplasms
  • Single Nucleotide Polymorphism
  • Genes
  • Alleles
  47 Citations (Scopus)

• Genome-wide association study identifies a novel locus associated with psychological distress in the Japanese population

  Koshimizu, H., Nogawa, S., Asano, S., Ikeda, M., Iwata, N., Takahashi, S., Saito, K. & Miyakawa, T., 01-12-2019, In: Translational psychiatry. 9, 1, 52.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Major Depressive Disorder
  • Psychology
  • Population
  • Far East
  1 Citation (Scopus)

• Genome-wide association study identifies a potent locus associated with human opioid sensitivity

  Nishizawa, D., Fukuda, K., Kasai, S., Hasegawa, J., Aoki, Y., Nishi, A., Saita, N., Koukita, Y., Nagashima, M., Katoh, R., Satoh, Y., Tagami, M., Higuchi, S., Ujike, H., Ozaki, N., Inada, T., Iwata, N., Sora, I., Iyo, M., Kondo, N. & 9 others, Won, M. J., Naruse, N., Uehara-Aoyama, K., Itokawa, M., Koga, M., Arinami, T., Kaneko, Y., Hayashida, M. & Ikeda, K., 01-2014, In: Molecular Psychiatry. 19, 1, p. 55-62 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Opioid Analgesics
  • Single Nucleotide Polymorphism
  • Substance-Related Disorders
  • Genetic Polymorphisms
  57 Citations (Scopus)

• Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma

  Kumar, V., Kato, N., Urabe, Y., Takahashi, A., Muroyama, R., Hosono, N., Otsuka, M., Tateishi, R., Omata, M., Nakagawa, H., Koike, K., Kamatani, N., Kubo, M., Nakamura, Y. & Matsuda, K., 05-2011, In: Nature Genetics. 43, 5, p. 455-458 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Hepacivirus
  • Hepatocellular Carcinoma
  • Chronic Hepatitis C
  • Single Nucleotide Polymorphism
  277 Citations (Scopus)

• Genome-wide association study identifies CDH13 as a susceptibility gene for rhododendrol-induced leukoderma

  Okamura, K., Abe, Y., Naka, I., Ohashi, J., Yagami, A., Matsunaga, K., Kobayashi, Y., Fukai, K., Tanemura, A., Katayama, I., Masui, Y., Ito, A., Yamashita, T., Nagai, H., Nishigori, C., Oiso, N., Aoyama, Y., Araki, Y., Saito, T., Hayashi, M. & 2 others, Hozumi, Y. & Suzuki, T., 01-11-2020, In: Pigment Cell and Melanoma Research. 33, 6, p. 826-833 8 p.

  Research output: Contribution to journal › Article › peer-review

  • rhododendrol
  • Genome-Wide Association Study
  • Vitiligo
  • Genes
  • Monophenol Monooxygenase

• Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

  Satake, W., Nakabayashi, Y., Mizuta, I., Hirota, Y., Ito, C., Kubo, M., Kawaguchi, T., Tsunoda, T., Watanabe, M., Takeda, A., Tomiyama, H., Nakashima, K., Hasegawa, K., Obata, F., Yoshikawa, T., Kawakami, H., Sakoda, S., Yamamoto, M., Hattori, N., Murata, M. & 2 others, Nakamura, Y. & Toda, T., 12-2009, In: Nature Genetics. 41, 12, p. 1303-1307 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetic Loci
  • Genome-Wide Association Study
  • Parkinson Disease
  • Parkinson Disease 16
  • Parkinsonian Disorders
  910 Citations (Scopus)

• Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population

  Hirota, T., Takahashi, A., Kubo, M., Tsunoda, T., Tomita, K., Sakashita, M., Yamada, T., Fujieda, S., Tanaka, S., Doi, S., Miyatake, A., Enomoto, T., Nishiyama, C., Nakano, N., Maeda, K., Okumura, K., Ogawa, H., Ikeda, S., Noguchi, E., Sakamoto, T. & 10 others, Hizawa, N., Ebe, K., Saeki, H., Sasaki, T., Ebihara, T., Amagai, M., Takeuchi, S., Furue, M., Nakamura, Y. & Tamari, M., 11-2012, In: Nature Genetics. 44, 11, p. 1222-1226 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Atopic Dermatitis
  • Vitamin D3 24-Hydroxylase
  • Population
  • Interleukin-13
  206 Citations (Scopus)

• Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population

  Takata, R., Akamatsu, S., Kubo, M., Takahashi, A., Hosono, N., Kawaguchi, T., Tsunoda, T., Inazawa, J., Kamatani, N., Ogawa, O., Fujioka, T., Nakamura, Y. & Nakagawa, H., 09-2010, In: Nature Genetics. 42, 9, p. 751-755 5 p.

  Research output: Contribution to journal › Letter › peer-review

  • Genome-Wide Association Study
  • Prostatic Neoplasms
  • Single Nucleotide Polymorphism
  • Population
  • Genetic Heterogeneity
  217 Citations (Scopus)

• Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21

  Tanikawa, C., Kamatani, Y., Toyoshima, O., Sakamoto, H., Ito, H., Takahashi, A., Momozawa, Y., Hirata, M., Fuse, N., Takai-Igarashi, T., Shimizu, A., Sasaki, M., Yamaji, T., Sawada, N., Iwasaki, M., Tsugane, S., Naito, M., Hishida, A., Wakai, K., Furusyo, N. & 13 others, Murakami, Y., Nakamura, Y., Imoto, I., Inazawa, J., Oze, I., Sato, N., Tanioka, F., Sugimura, H., Hirose, H., Yoshida, T., Matsuo, K., Kubo, M. & Matsuda, K., 12-2018, In: Cancer science. 109, 12, p. 4015-4024 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genome-Wide Association Study
  • Stomach Neoplasms
  • Odds Ratio
  • Genetic Variation
  • Multigene Family
  11 Citations (Scopus)