A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11

Michitoshi Goto; Takeshi Takada; Eiichi Saito; Yasutaka Hiraide; Toshihiko Matsumoto

A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11

Michitoshi Goto, Takeshi Takada, Eiichi Saito, Yasutaka Hiraide, Toshihiko Matsumoto

Research output: Contribution to journal › Article › peer-review

Abstract

A 57-year-old male patient with upper epigastric discomfort was introduced to our hospital from another clinic because of gastric cancer. Several examinations showed massive liver metastasis and paraaortic lymph node metastasis from Type-3 gastric cancer beneath the posterior wall of the pyloric antrum. First we tried infusion of CDDP (10 mg/day for days 1-5 and 8-12) and continuous infusion of 5-FU (500 mg/day for 14 days). Concurrently, we added infusion of CPT-11 (80 mg/day on days 1,8). After 3 courses of chemotherapy, the tumor had decreased remarkably in size. Moreover, liver metastasis and paraaortic lymph node metastasis had vanished. This regimen thus appears to be effective for advanced gastric carcinoma.

Original language	English
Pages (from-to)	1963-1966
Number of pages	4
Journal	Gan to kagaku ryoho. Cancer & chemotherapy
Volume	30
Issue number	12
Publication status	Published - 11-2003
Externally published	Yes

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

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title = "A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11",

abstract = "A 57-year-old male patient with upper epigastric discomfort was introduced to our hospital from another clinic because of gastric cancer. Several examinations showed massive liver metastasis and paraaortic lymph node metastasis from Type-3 gastric cancer beneath the posterior wall of the pyloric antrum. First we tried infusion of CDDP (10 mg/day for days 1-5 and 8-12) and continuous infusion of 5-FU (500 mg/day for 14 days). Concurrently, we added infusion of CPT-11 (80 mg/day on days 1,8). After 3 courses of chemotherapy, the tumor had decreased remarkably in size. Moreover, liver metastasis and paraaortic lymph node metastasis had vanished. This regimen thus appears to be effective for advanced gastric carcinoma.",

author = "Michitoshi Goto and Takeshi Takada and Eiichi Saito and Yasutaka Hiraide and Toshihiko Matsumoto",

note = "Copyright: This record is sourced from MEDLINE{\textregistered}/PubMed{\textregistered}, a database of the U.S. National Library of Medicine",

year = "2003",

month = nov,

language = "English",

volume = "30",

pages = "1963--1966",

journal = "Gan to kagaku ryoho. Cancer & chemotherapy",

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publisher = "Japanese Journal of Cancer and Chemotherapy Publishers Inc.",

number = "12",

}

A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11. / Goto, Michitoshi; Takada, Takeshi; Saito, Eiichi et al.
In: Gan to kagaku ryoho. Cancer & chemotherapy, Vol. 30, No. 12, 11.2003, p. 1963-1966.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11

AU - Goto, Michitoshi

AU - Takada, Takeshi

AU - Saito, Eiichi

AU - Hiraide, Yasutaka

AU - Matsumoto, Toshihiko

N1 - Copyright: This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

PY - 2003/11

Y1 - 2003/11

N2 - A 57-year-old male patient with upper epigastric discomfort was introduced to our hospital from another clinic because of gastric cancer. Several examinations showed massive liver metastasis and paraaortic lymph node metastasis from Type-3 gastric cancer beneath the posterior wall of the pyloric antrum. First we tried infusion of CDDP (10 mg/day for days 1-5 and 8-12) and continuous infusion of 5-FU (500 mg/day for 14 days). Concurrently, we added infusion of CPT-11 (80 mg/day on days 1,8). After 3 courses of chemotherapy, the tumor had decreased remarkably in size. Moreover, liver metastasis and paraaortic lymph node metastasis had vanished. This regimen thus appears to be effective for advanced gastric carcinoma.

AB - A 57-year-old male patient with upper epigastric discomfort was introduced to our hospital from another clinic because of gastric cancer. Several examinations showed massive liver metastasis and paraaortic lymph node metastasis from Type-3 gastric cancer beneath the posterior wall of the pyloric antrum. First we tried infusion of CDDP (10 mg/day for days 1-5 and 8-12) and continuous infusion of 5-FU (500 mg/day for 14 days). Concurrently, we added infusion of CPT-11 (80 mg/day on days 1,8). After 3 courses of chemotherapy, the tumor had decreased remarkably in size. Moreover, liver metastasis and paraaortic lymph node metastasis had vanished. This regimen thus appears to be effective for advanced gastric carcinoma.

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UR - http://www.scopus.com/inward/citedby.url?scp=0642303128&partnerID=8YFLogxK

M3 - Article

C2 - 14650968

AN - SCOPUS:0642303128

SN - 0385-0684

VL - 30

SP - 1963

EP - 1966

JO - Gan to kagaku ryoho. Cancer & chemotherapy

JF - Gan to kagaku ryoho. Cancer & chemotherapy

IS - 12

ER -

A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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