A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11

Michitoshi Goto, Takeshi Takada, Eiichi Saito, Yasutaka Hiraide, Toshihiko Matsumoto

Research output: Contribution to journalArticle

Abstract

A 57-year-old male patient with upper epigastric discomfort was introduced to our hospital from another clinic because of gastric cancer. Several examinations showed massive liver metastasis and paraaortic lymph node metastasis from Type-3 gastric cancer beneath the posterior wall of the pyloric antrum. First we tried infusion of CDDP (10 mg/day for days 1-5 and 8-12) and continuous infusion of 5-FU (500 mg/day for 14 days). Concurrently, we added infusion of CPT-11 (80 mg/day on days 1,8). After 3 courses of chemotherapy, the tumor had decreased remarkably in size. Moreover, liver metastasis and paraaortic lymph node metastasis had vanished. This regimen thus appears to be effective for advanced gastric carcinoma.

Original languageEnglish
Pages (from-to)1963-1966
Number of pages4
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume30
Issue number12
Publication statusPublished - 01-11-2003

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irinotecan
Liver Neoplasms
Combination Drug Therapy
Fluorouracil
Lymph Nodes
Neoplasm Metastasis
Stomach Neoplasms
Pyloric Antrum
Liver
Stomach
Carcinoma
Drug Therapy

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

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title = "A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11",
abstract = "A 57-year-old male patient with upper epigastric discomfort was introduced to our hospital from another clinic because of gastric cancer. Several examinations showed massive liver metastasis and paraaortic lymph node metastasis from Type-3 gastric cancer beneath the posterior wall of the pyloric antrum. First we tried infusion of CDDP (10 mg/day for days 1-5 and 8-12) and continuous infusion of 5-FU (500 mg/day for 14 days). Concurrently, we added infusion of CPT-11 (80 mg/day on days 1,8). After 3 courses of chemotherapy, the tumor had decreased remarkably in size. Moreover, liver metastasis and paraaortic lymph node metastasis had vanished. This regimen thus appears to be effective for advanced gastric carcinoma.",
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A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11. / Goto, Michitoshi; Takada, Takeshi; Saito, Eiichi; Hiraide, Yasutaka; Matsumoto, Toshihiko.

In: Gan to kagaku ryoho. Cancer & chemotherapy, Vol. 30, No. 12, 01.11.2003, p. 1963-1966.

Research output: Contribution to journalArticle

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T1 - A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11

AU - Goto, Michitoshi

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AU - Hiraide, Yasutaka

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