TY - JOUR
T1 - A case of autoimmune type 1 diabetes mellitus complicated by myasthenia gravis and graves' disease
AU - Nakajima, Shoko
AU - Matsunaga, Masaaki
AU - Shibata, Miyuki
AU - Kusada, Noriko
AU - Nakashima, Kotaro
AU - Inagaki, Akemi
AU - Yasui, Keizo
AU - Yoshioka, Hiromu
AU - Tsuduki, Toyonori
AU - Nomura, Yoshio
PY - 2014
Y1 - 2014
N2 - A 35-year-old woman with type 1 diabetes was admitted to our hospital after reporting general fatigue, palpitations and diplopia in February 20xy. At 15 years of age, she was started on treatment with insulin therapy for type 1 diabetes. Five years later, she received a diagnosis of myasthenia gravis (MG'. On admission, a blood test showed apparent Graves' disease, and the patient's glycemic control was poor. Therefore, we began treatment with an insulin pump in addition to thymectomy for MG followed by the administration of tacrolimus and prednisolone as immunosuppressive therapy. Thereafter, tight glycemic control was maintained with adjustments to the basal injection rate. The patient was therefore given a diagnosis of type 3 polyglandular autoimmune syndrome complicated by type 1 diabetes mellitus, MG and Graves' disease in which the difficult to control diabetes was successfully managed with an insulin pump.
AB - A 35-year-old woman with type 1 diabetes was admitted to our hospital after reporting general fatigue, palpitations and diplopia in February 20xy. At 15 years of age, she was started on treatment with insulin therapy for type 1 diabetes. Five years later, she received a diagnosis of myasthenia gravis (MG'. On admission, a blood test showed apparent Graves' disease, and the patient's glycemic control was poor. Therefore, we began treatment with an insulin pump in addition to thymectomy for MG followed by the administration of tacrolimus and prednisolone as immunosuppressive therapy. Thereafter, tight glycemic control was maintained with adjustments to the basal injection rate. The patient was therefore given a diagnosis of type 3 polyglandular autoimmune syndrome complicated by type 1 diabetes mellitus, MG and Graves' disease in which the difficult to control diabetes was successfully managed with an insulin pump.
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M3 - Article
AN - SCOPUS:84927606409
SN - 0021-437X
VL - 58
SP - 198
EP - 205
JO - Journal of the Japan Diabetes Society
JF - Journal of the Japan Diabetes Society
IS - 3
ER -
