A case of Barrett's esophageal carcinoma successfully treated with TS-1 in an elderly patient

Hiroki Imazu; Masahiro Ochiai; Yoichi Sakurai; Yoshiyuki Komori; Ichiro Uyama; Toshiki Matsubara; Shigeru Hasegawa; Yasuko Nakamura; Mitsutaka Syoji; Ikuo Yoshida; Toshihiko Masui; Syuhei Tonomura; Kichizou Nagai; Hideaki Hattori

A case of Barrett's esophageal carcinoma successfully treated with TS-1 in an elderly patient

Hiroki Imazu, Masahiro Ochiai, Yoichi Sakurai, Yoshiyuki Komori, Ichiro Uyama, Toshiki Matsubara, Shigeru Hasegawa, Yasuko Nakamura, Mitsutaka Syoji, Ikuo Yoshida, Toshihiko Masui, Syuhei Tonomura, Kichizou Nagai, Hideaki Hattori

Advanced Robotic and Endoscopic Surgery

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

A 92-year-old man was admitted to the hospital for rehabilitation. Upper gastrointestinal endoscopy was performed 2 weeks after admission because of vomiting which was found to be due to a Barrett's esophageal carcinoma at the lower esophagus. We chose chemotherapy with TS-1 at the dose of 50 mg/day in consideration of his age and performance status. His difficulty in swallowing disappeared rapidly. After 7 days of treatment, grade 3 anorexia appeared, so the dosage of TS-1 was reduced to 25 mg/day. After the reduction of TS-1, anorexia soon disappeared. The regimen consisted of TS-1 every 6 weeks as 1 cycle. After 7 cycles of treatment, upper gastrointestinal endoscopy and upper gastrointestinal series revealed that the tumor had a completely disappeared. The effects of chemotherapy were judged as CR. This case suggests that administration of TS-1 is an effective choice of chemotherapy not only for gastric carcinoma but also Barrett's esophageal carcinoma.

Original language	English
Pages (from-to)	575-577
Number of pages	3
Journal	Gan to kagaku ryoho. Cancer & chemotherapy
Volume	31
Issue number	4
Publication status	Published - 04-2004

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "A case of Barrett's esophageal carcinoma successfully treated with TS-1 in an elderly patient",

abstract = "A 92-year-old man was admitted to the hospital for rehabilitation. Upper gastrointestinal endoscopy was performed 2 weeks after admission because of vomiting which was found to be due to a Barrett's esophageal carcinoma at the lower esophagus. We chose chemotherapy with TS-1 at the dose of 50 mg/day in consideration of his age and performance status. His difficulty in swallowing disappeared rapidly. After 7 days of treatment, grade 3 anorexia appeared, so the dosage of TS-1 was reduced to 25 mg/day. After the reduction of TS-1, anorexia soon disappeared. The regimen consisted of TS-1 every 6 weeks as 1 cycle. After 7 cycles of treatment, upper gastrointestinal endoscopy and upper gastrointestinal series revealed that the tumor had a completely disappeared. The effects of chemotherapy were judged as CR. This case suggests that administration of TS-1 is an effective choice of chemotherapy not only for gastric carcinoma but also Barrett's esophageal carcinoma.",

author = "Hiroki Imazu and Masahiro Ochiai and Yoichi Sakurai and Yoshiyuki Komori and Ichiro Uyama and Toshiki Matsubara and Shigeru Hasegawa and Yasuko Nakamura and Mitsutaka Syoji and Ikuo Yoshida and Toshihiko Masui and Syuhei Tonomura and Kichizou Nagai and Hideaki Hattori",

year = "2004",

month = apr,

language = "English",

volume = "31",

pages = "575--577",

journal = "Gan to kagaku ryoho. Cancer & chemotherapy",

issn = "0385-0684",

publisher = "Japanese Journal of Cancer and Chemotherapy Publishers Inc.",

number = "4",

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TY - JOUR

T1 - A case of Barrett's esophageal carcinoma successfully treated with TS-1 in an elderly patient

AU - Imazu, Hiroki

AU - Ochiai, Masahiro

AU - Sakurai, Yoichi

AU - Komori, Yoshiyuki

AU - Uyama, Ichiro

AU - Matsubara, Toshiki

AU - Hasegawa, Shigeru

AU - Nakamura, Yasuko

AU - Syoji, Mitsutaka

AU - Yoshida, Ikuo

AU - Masui, Toshihiko

AU - Tonomura, Syuhei

AU - Nagai, Kichizou

AU - Hattori, Hideaki

PY - 2004/4

Y1 - 2004/4

N2 - A 92-year-old man was admitted to the hospital for rehabilitation. Upper gastrointestinal endoscopy was performed 2 weeks after admission because of vomiting which was found to be due to a Barrett's esophageal carcinoma at the lower esophagus. We chose chemotherapy with TS-1 at the dose of 50 mg/day in consideration of his age and performance status. His difficulty in swallowing disappeared rapidly. After 7 days of treatment, grade 3 anorexia appeared, so the dosage of TS-1 was reduced to 25 mg/day. After the reduction of TS-1, anorexia soon disappeared. The regimen consisted of TS-1 every 6 weeks as 1 cycle. After 7 cycles of treatment, upper gastrointestinal endoscopy and upper gastrointestinal series revealed that the tumor had a completely disappeared. The effects of chemotherapy were judged as CR. This case suggests that administration of TS-1 is an effective choice of chemotherapy not only for gastric carcinoma but also Barrett's esophageal carcinoma.

AB - A 92-year-old man was admitted to the hospital for rehabilitation. Upper gastrointestinal endoscopy was performed 2 weeks after admission because of vomiting which was found to be due to a Barrett's esophageal carcinoma at the lower esophagus. We chose chemotherapy with TS-1 at the dose of 50 mg/day in consideration of his age and performance status. His difficulty in swallowing disappeared rapidly. After 7 days of treatment, grade 3 anorexia appeared, so the dosage of TS-1 was reduced to 25 mg/day. After the reduction of TS-1, anorexia soon disappeared. The regimen consisted of TS-1 every 6 weeks as 1 cycle. After 7 cycles of treatment, upper gastrointestinal endoscopy and upper gastrointestinal series revealed that the tumor had a completely disappeared. The effects of chemotherapy were judged as CR. This case suggests that administration of TS-1 is an effective choice of chemotherapy not only for gastric carcinoma but also Barrett's esophageal carcinoma.

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M3 - Article

C2 - 15114702

AN - SCOPUS:2342660233

SN - 0385-0684

VL - 31

SP - 575

EP - 577

JO - Gan to kagaku ryoho. Cancer & chemotherapy

JF - Gan to kagaku ryoho. Cancer & chemotherapy

IS - 4

ER -

A case of Barrett's esophageal carcinoma successfully treated with TS-1 in an elderly patient

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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