A case of Barrett's esophageal carcinoma successfully treated with TS-1 in an elderly patient

Hiroki Imazu, Masahiro Ochiai, Yoichi Sakurai, Yoshiyuki Komori, Ichiro Uyama, Toshiki Matsubara, Shigeru Hasegawa, Yasuko Nakamura, Mitsutaka Syoji, Ikuo Yoshida, Toshihiko Masui, Syuhei Tonomura, Kichizou Nagai, Hideaki Hattori

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

A 92-year-old man was admitted to the hospital for rehabilitation. Upper gastrointestinal endoscopy was performed 2 weeks after admission because of vomiting which was found to be due to a Barrett's esophageal carcinoma at the lower esophagus. We chose chemotherapy with TS-1 at the dose of 50 mg/day in consideration of his age and performance status. His difficulty in swallowing disappeared rapidly. After 7 days of treatment, grade 3 anorexia appeared, so the dosage of TS-1 was reduced to 25 mg/day. After the reduction of TS-1, anorexia soon disappeared. The regimen consisted of TS-1 every 6 weeks as 1 cycle. After 7 cycles of treatment, upper gastrointestinal endoscopy and upper gastrointestinal series revealed that the tumor had a completely disappeared. The effects of chemotherapy were judged as CR. This case suggests that administration of TS-1 is an effective choice of chemotherapy not only for gastric carcinoma but also Barrett's esophageal carcinoma.

Original languageEnglish
Pages (from-to)575-577
Number of pages3
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume31
Issue number4
Publication statusPublished - 04-2004

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'A case of Barrett's esophageal carcinoma successfully treated with TS-1 in an elderly patient'. Together they form a unique fingerprint.

Cite this