TY - JOUR
T1 - A case of drug-induced pneumonitis due to amiodarone
AU - Kobayashi, Kashin
AU - Horiguchi, Takahiko
AU - Kondo, Rieko
AU - Shiga, Mamoru
AU - Hirose, Masahiro
AU - Itou, Tomohiro
AU - Torigoe, Hiroshi
AU - Hayashi, Nobuyuki
AU - Ouhira, Daisuke
PY - 2006
Y1 - 2006
N2 - An 80-year-old man, who had been taking the antiarrhythmic drug amiodarone for chronic atrial fibrillation since October 2004, developed dyspnea and fever in June 2005, and was admitted to our hospital. Chest X-ray and CT scan showed ground-glass opacities in all lung fields. Arterial blood gas analysis revealed hypoxemia. These findings led to a diagnosis of acute respiratory distress syndrome. Oral amiodarone was discontinued, and steroid pulse therapy was started: however, the disease progressed rapidly, and the patient died on the fourth hospital day. Autopsy showed diffuse alveolar damage, accumulation of edema fluid in the alveolar spaces, and the presence of foamy macrophages, leading to a diagnosis of amiodarone-induced pulmonary damage.
AB - An 80-year-old man, who had been taking the antiarrhythmic drug amiodarone for chronic atrial fibrillation since October 2004, developed dyspnea and fever in June 2005, and was admitted to our hospital. Chest X-ray and CT scan showed ground-glass opacities in all lung fields. Arterial blood gas analysis revealed hypoxemia. These findings led to a diagnosis of acute respiratory distress syndrome. Oral amiodarone was discontinued, and steroid pulse therapy was started: however, the disease progressed rapidly, and the patient died on the fourth hospital day. Autopsy showed diffuse alveolar damage, accumulation of edema fluid in the alveolar spaces, and the presence of foamy macrophages, leading to a diagnosis of amiodarone-induced pulmonary damage.
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M3 - Article
C2 - 17185916
AN - SCOPUS:33846477772
SN - 0021-4884
VL - 55
SP - 1551
EP - 1555
JO - Japanese Journal of Allergology
JF - Japanese Journal of Allergology
IS - 12
ER -