A case of gastric carcinosarcoma with distant metastasis for which chemotherapy with S-1 plus cisplatin was transiently effective

Osamu Maeda, Takafumi Ando, Kazuhiro Ishiguro, Osamu Watanabe, Ryoji Miyahara, Tomoko Miyata, Keita Itatsu, Yuichi Ando, Hidemi Goto

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Gastric carcinosarcoma is a very rare tumor for which there is no standard regimen of chemotherapy. We report a case of a 61-year-old woman having gastric carcinosarcoma with liver and lymph node metastases. She underwent distal gastrectomy due to uncontrollable bleeding from the tumor. Histopathological examination of the resected specimen revealed adenocarcinoma and a sarcomatous component with spindle-shaped tumor cells accompanied by a cartilage formation. She was diagnosed as carcinosarcoma of the stomach with distant metastases, and underwent chemotherapy with S-1 plus cisplatin. Since the liver metastasis shrank once, the treatment was considered to be effective. After the metastatic lesions progressed, she underwent treatment with doxorubicin plus ifosfamide for second-line chemotherapy, and docetaxel subsequently for third-line chemotherapy. The metastatic lesions progressed rapidly and she died 9 months after diagnosis.

Original languageEnglish
Pages (from-to)252-259
Number of pages8
JournalMetallography, Microstructure, and Analysis
Volume3
Issue number4
DOIs
Publication statusPublished - 10-2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Metals and Alloys

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