A Case of Gastric Remnant Cancer with Multiple Liver Metastases Treated with SOX + Nivolumab Therapy and Conversion Surgery

Kazuma Horiguchi; Takahiro Tashiro; Daisuke Koike; Masahiro Ito; Hiroyuki Kato; Satoshi Arakawa; Masahiro Shimura; Hironobu Yasuaka; Takahiko Higashiguchi; Yoshiki Kunimura; Hiroki Tani; Yutaro Kato; Tsunekazu Hanai; Akihiko Horiguchi

A Case of Gastric Remnant Cancer with Multiple Liver Metastases Treated with SOX + Nivolumab Therapy and Conversion Surgery

Kazuma Horiguchi
, Takahiro Tashiro
, Daisuke Koike
, Masahiro Ito
, Hiroyuki Kato
, Satoshi Arakawa
, Masahiro Shimura
, Hironobu Yasuaka
, Takahiko Higashiguchi
, Yoshiki Kunimura
, Hiroki Tani
, Yutaro Kato
, Tsunekazu Hanai
, Akihiko Horiguchi

Research output: Contribution to journal › Article › peer-review

Abstract

A male patient in his 60s with a history of distal gastrectomy (Billroth Ⅱ) for duodenal ulcer 40 years ago. Fecal occult blood was positive, and endoscopy revealed a type 3 tumor at the anastomotic site. He was referred to our hospital and diagnosed with remnant gastric cancer and multiple liver metastases (cT4aN1M1, Stage ⅣB). He received 18 courses of SOX + nivolumab chemotherapy. Liver metastases disappeared, but PET-CT showed residual uptake at the primary site. Laparoscopic total remnant gastrectomy with D2 lymph node dissection was performed as a conversion surgery. Pathology showed no residual cancer. Chemotherapy with nivolumab was effective in enabling conversion surgery.

Original language	English
Pages (from-to)	281-283
Number of pages	3
Journal	Japanese Journal of Cancer and Chemotherapy
Volume	53
Issue number	4
Publication status	Published - 01-04-2026

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

Cite this

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title = "A Case of Gastric Remnant Cancer with Multiple Liver Metastases Treated with SOX + Nivolumab Therapy and Conversion Surgery",

abstract = "A male patient in his 60s with a history of distal gastrectomy (Billroth Ⅱ) for duodenal ulcer 40 years ago. Fecal occult blood was positive, and endoscopy revealed a type 3 tumor at the anastomotic site. He was referred to our hospital and diagnosed with remnant gastric cancer and multiple liver metastases (cT4aN1M1, Stage ⅣB). He received 18 courses of SOX + nivolumab chemotherapy. Liver metastases disappeared, but PET-CT showed residual uptake at the primary site. Laparoscopic total remnant gastrectomy with D2 lymph node dissection was performed as a conversion surgery. Pathology showed no residual cancer. Chemotherapy with nivolumab was effective in enabling conversion surgery.",

author = "Kazuma Horiguchi and Takahiro Tashiro and Daisuke Koike and Masahiro Ito and Hiroyuki Kato and Satoshi Arakawa and Masahiro Shimura and Hironobu Yasuaka and Takahiko Higashiguchi and Yoshiki Kunimura and Hiroki Tani and Yutaro Kato and Tsunekazu Hanai and Akihiko Horiguchi",

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month = apr,

day = "1",

language = "English",

volume = "53",

pages = "281--283",

journal = "Japanese Journal of Cancer and Chemotherapy",

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TY - JOUR

T1 - A Case of Gastric Remnant Cancer with Multiple Liver Metastases Treated with SOX + Nivolumab Therapy and Conversion Surgery

AU - Horiguchi, Kazuma

AU - Tashiro, Takahiro

AU - Koike, Daisuke

AU - Ito, Masahiro

AU - Kato, Hiroyuki

AU - Arakawa, Satoshi

AU - Shimura, Masahiro

AU - Yasuaka, Hironobu

AU - Higashiguchi, Takahiko

AU - Kunimura, Yoshiki

AU - Tani, Hiroki

AU - Kato, Yutaro

AU - Hanai, Tsunekazu

AU - Horiguchi, Akihiko

PY - 2026/4/1

Y1 - 2026/4/1

N2 - A male patient in his 60s with a history of distal gastrectomy (Billroth Ⅱ) for duodenal ulcer 40 years ago. Fecal occult blood was positive, and endoscopy revealed a type 3 tumor at the anastomotic site. He was referred to our hospital and diagnosed with remnant gastric cancer and multiple liver metastases (cT4aN1M1, Stage ⅣB). He received 18 courses of SOX + nivolumab chemotherapy. Liver metastases disappeared, but PET-CT showed residual uptake at the primary site. Laparoscopic total remnant gastrectomy with D2 lymph node dissection was performed as a conversion surgery. Pathology showed no residual cancer. Chemotherapy with nivolumab was effective in enabling conversion surgery.

AB - A male patient in his 60s with a history of distal gastrectomy (Billroth Ⅱ) for duodenal ulcer 40 years ago. Fecal occult blood was positive, and endoscopy revealed a type 3 tumor at the anastomotic site. He was referred to our hospital and diagnosed with remnant gastric cancer and multiple liver metastases (cT4aN1M1, Stage ⅣB). He received 18 courses of SOX + nivolumab chemotherapy. Liver metastases disappeared, but PET-CT showed residual uptake at the primary site. Laparoscopic total remnant gastrectomy with D2 lymph node dissection was performed as a conversion surgery. Pathology showed no residual cancer. Chemotherapy with nivolumab was effective in enabling conversion surgery.

UR - https://www.scopus.com/pages/publications/105040131705

UR - https://www.scopus.com/pages/publications/105040131705#tab=citedBy

M3 - Article

C2 - 42178634

AN - SCOPUS:105040131705

SN - 0385-0684

VL - 53

SP - 281

EP - 283

JO - Japanese Journal of Cancer and Chemotherapy

JF - Japanese Journal of Cancer and Chemotherapy

IS - 4

ER -

A Case of Gastric Remnant Cancer with Multiple Liver Metastases Treated with SOX + Nivolumab Therapy and Conversion Surgery

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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