A case of locally advanced sigmoid colon cancer invading the bladder and seminal vesicle effectively treated with preoperative mFOLFOX6

Kazuhisa Hirayama, Tadataka Hayashi, Yoshiro Nishiwaki, Megumu Kamishima, Satoru Furuhashi, Hisataka Fukushima, Yuuki Nakata, Hiroaki Tamura, Toshikazu Kanai, Yoshito Ikematsu, Hiroki Mori, Takachika Ozawa

Research output: Contribution to journalArticlepeer-review

Abstract

A 77-year-old male was admitted to our hospital complaining of dyschezia. Computed tomography (CT) and colonoscopy (CF) revealed a huge sigmoid colon cancer invading the bladder and seminal vesicle. Chemotherapy with mFOLFOX6 was initiated preoperatively, and the tumor shrunk markedly after seven courses of treatment. Pelvic exenteration with negative margins was carried out. The patient is still alive and disease-free 16 months after surgery. It was suggested that mFOLFOX6 may be useful for advanced colon cancer invading other organs when used as neoadjuvant chemotherapy.

Original languageEnglish
Pages (from-to)2663-2666
Number of pages4
JournalJapanese Journal of Cancer and Chemotherapy
Volume38
Issue number13
Publication statusPublished - 15-12-2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Medicine

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