A case of malignant lymphoma of the jejunum that developed stenosis and perforation after a complete response to chemotherapy

Atsushi Sugimoto, Masaharu Tada, Tomoe Taji, Yudai Houjo, Yu Kanokogi, Masaaki Hirata, Yusuke Fujita, Yusuke Kawasaki, Takashi Sakamoto, Junichi Yoshikawa, Hideaki Iwama, Shinichiro Usuki, Yoshiharu Shirakata, Jun Tamura, Atsuhiko Maki

Research output: Contribution to journalArticlepeer-review

Abstract

A 57-year-old woman was admitted owing to epigastric pain. Abdominal computed tomography demonstrated a tumor in the origin of the jejunum. After an endoscopic biopsy, we diagnosed diffuse large B-cell lymphoma. We treated her with CHOP chemotherapy because pancreaticoduodenectomy is highly invasive. After 1 course of chemotherapy, the tumor was reduced. However, she developed a jejunal stenosis; therefore, we performed laparoscopic gastrojejunostomy. Furthermore, she developed perforated peritonitis on the sixth day after the surgery, and therefore, an emergency partial jejunum resection was performed. Histopathologically, viable lymphoma cells were not found in the resected intestine. She had a complete response 10 months after the surgery. Chemotherapy may cause intestinal stenosis and perforation requiring surgery; therefore, decisions about surgical procedures must be made carefully.

Original languageEnglish
Pages (from-to)341-343
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Volume44
Issue number4
Publication statusPublished - 04-2017
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'A case of malignant lymphoma of the jejunum that developed stenosis and perforation after a complete response to chemotherapy'. Together they form a unique fingerprint.

Cite this