TY - JOUR
T1 - A case of malignant lymphoma of the jejunum that developed stenosis and perforation after a complete response to chemotherapy
AU - Sugimoto, Atsushi
AU - Tada, Masaharu
AU - Taji, Tomoe
AU - Houjo, Yudai
AU - Kanokogi, Yu
AU - Hirata, Masaaki
AU - Fujita, Yusuke
AU - Kawasaki, Yusuke
AU - Sakamoto, Takashi
AU - Yoshikawa, Junichi
AU - Iwama, Hideaki
AU - Usuki, Shinichiro
AU - Shirakata, Yoshiharu
AU - Tamura, Jun
AU - Maki, Atsuhiko
PY - 2017/4
Y1 - 2017/4
N2 - A 57-year-old woman was admitted owing to epigastric pain. Abdominal computed tomography demonstrated a tumor in the origin of the jejunum. After an endoscopic biopsy, we diagnosed diffuse large B-cell lymphoma. We treated her with CHOP chemotherapy because pancreaticoduodenectomy is highly invasive. After 1 course of chemotherapy, the tumor was reduced. However, she developed a jejunal stenosis; therefore, we performed laparoscopic gastrojejunostomy. Furthermore, she developed perforated peritonitis on the sixth day after the surgery, and therefore, an emergency partial jejunum resection was performed. Histopathologically, viable lymphoma cells were not found in the resected intestine. She had a complete response 10 months after the surgery. Chemotherapy may cause intestinal stenosis and perforation requiring surgery; therefore, decisions about surgical procedures must be made carefully.
AB - A 57-year-old woman was admitted owing to epigastric pain. Abdominal computed tomography demonstrated a tumor in the origin of the jejunum. After an endoscopic biopsy, we diagnosed diffuse large B-cell lymphoma. We treated her with CHOP chemotherapy because pancreaticoduodenectomy is highly invasive. After 1 course of chemotherapy, the tumor was reduced. However, she developed a jejunal stenosis; therefore, we performed laparoscopic gastrojejunostomy. Furthermore, she developed perforated peritonitis on the sixth day after the surgery, and therefore, an emergency partial jejunum resection was performed. Histopathologically, viable lymphoma cells were not found in the resected intestine. She had a complete response 10 months after the surgery. Chemotherapy may cause intestinal stenosis and perforation requiring surgery; therefore, decisions about surgical procedures must be made carefully.
KW - Chemotherapy
KW - Intestinal malignant lymphoma
KW - Stenosis
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UR - http://www.scopus.com/inward/citedby.url?scp=85021752012&partnerID=8YFLogxK
M3 - Article
C2 - 28428518
AN - SCOPUS:85021752012
SN - 0385-0684
VL - 44
SP - 341
EP - 343
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
IS - 4
ER -