A case of malignant melanoma arising from palmoplantar keratoderma

Hajime Tomita, Youhei Iwata, Humihide Ogawa, Shinichi Sato, Yuuichirou Akiyama, Taizou Matushita

Research output: Contribution to journalArticlepeer-review


We report a 50-year-old female patient of malignant melanoma (MM) on the right sole arising from a lesion of palmoplantar keratoderma. The keratotic lesion appeared on her palm and sole at birth. She was treated with topical ointment, and shave resection of the keratotic lesion was performed many times. The melanotic macule on the right sole had appeared two years before her visiting our hospital. Because of the spreading pigmented macule and developing erosive nodule, she visited our hospital in August, 2008. The clinical findings revealed malignant melanoma with palmoplantar keratoderma. The tumor resection was performed with 2 cm margin. After treatment of etretinate for the keratoderma, the remaining pigmented macule appeared. Additional operation for removal of the remaining tumor was performed. It is suggested that malignant melanoma with palmoplantar keratoderma should be treated carefully before operation for the accurate resection margin.

Original languageEnglish
Pages (from-to)625-629
Number of pages5
JournalNishinihon Journal of Dermatology
Issue number6
Publication statusPublished - 2008
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Dermatology


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