A case of metachronous liver metastasis of gallbladder cancer successfully treated by hepatectomy after chemotherapy

Yukio Asano, Satoshi Arakawa, Masahiro Ito, Hiroyuki Kato, Masahiro Shimura, Chihiro Hayashi, Takayuki Ochi, Kenshiro Kamio, Toki Kawai, Hironobu Yasuoka, Takahiko Higashiguchi, Akihiko Horiguchi

Research output: Contribution to journalArticlepeer-review

Abstract

We present the case of a 66-year-old female diagnosed with gallbladder cancer that was initially discovered with contrast enhanced computed tomography. The primary gall bladder tumor displayed heterogeneous enhancement. The patient underwent cholecystectomy with full-thickness excision of the gallbladder cancer. After 3 rounds of adjuvant chemotherapy with the oral fluoropyrimidine derivative, S-1 (administered for 4 weeks at 120 mg/day and then stopped for 2 weeks), a metastasis measuring 15 mm in diameter emerged within hepatic segment 5. The chemotherapy regimen was altered to include 6 months of combination therapy with gemcitabine (1,000 mg/m') and cisplatin (25 mg/m2) given once every week for 2 weeks and then stopped for 1 week. The hepatic metastasis decreased in size to 8 mm in diameter, and a partial liver resection was performed. After hepatectomy, the patient remains alive and without disease recurrence. Key words: Liver metastasis of gallbladder cancer, Chemotherapy, Metachronous liver metastasis (Received Mar. 9, 2020/Accepted May 13, 2020).

Original languageEnglish
Pages (from-to)1501-1504
Number of pages4
JournalJapanese Journal of Cancer and Chemotherapy
Volume47
Issue number10
Publication statusPublished - 10-2020

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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