A case of neuroendocrine carcinoma in a diverticulum of the bladder

Hiroyuki Muramatsu, Kent Kanao, Shingo Morinaga, Keishi Kajikawa, Ikuo Kobayashi, Genya Nishikawa, Takahiko Yoshizawa, Yoshiharu Kato, Masahito Watanabe, Kenji Zennami, Kogenta Nakamura, Makoto Sumitomo

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Abstract

We report a case of neuroendocrine carcinoma in a diverticulum of the bladder. A 65-year-old Japanese woman visited our hospital with the chief complaint of gross hematuria. Cystoscopy revealed a non-papillary broad-based tumor in a diverticulum of the posterior wall. She underwent transurethral resection of bladder tumor (TURBT) and subsequendy total cystectomy with ileal conduit on the diagnosis of an invasive urothelial carcinoma. There was no residual tumor in the surgical specimen. Immunohisto-chemistry of TUR specimens showed positive synaptophysin, chromogranin A, CD56 and high ratio of positive Ki-67. Finally, it was diagnosed as a neuroendocrine carcinoma of the bladder. To our knowledge, this is the second case report of the neuroendocrine tumor or small cell carcinoma in a diverticulum of the urinary bladder in the Japanese literature.

Original languageEnglish
Pages (from-to)439-442
Number of pages4
JournalActa Urologica Japonica
Volume60
Issue number9
Publication statusPublished - 01-09-2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Urology

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  • Cite this

    Muramatsu, H., Kanao, K., Morinaga, S., Kajikawa, K., Kobayashi, I., Nishikawa, G., Yoshizawa, T., Kato, Y., Watanabe, M., Zennami, K., Nakamura, K., & Sumitomo, M. (2014). A case of neuroendocrine carcinoma in a diverticulum of the bladder. Acta Urologica Japonica, 60(9), 439-442.