A Case of Non-24-Hour Sleep-Wake Rhythm Disorder Treated With a Low Dose of Ramelteon and Behavioral Education

Akiko Watanabe; Marina Hirose; Chiaki Arakawa; Nakao Iwata; Tsuyoshi Kitajima

doi:10.5664/jcsm.7244

A Case of Non-24-Hour Sleep-Wake Rhythm Disorder Treated With a Low Dose of Ramelteon and Behavioral Education

Akiko Watanabe, Marina Hirose, Chiaki Arakawa, Nakao Iwata, Tsuyoshi Kitajima

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Non-24-hour sleep-wake rhythm disorder (N24SWD) occurs when the intrinsic circadian pacemaker does not entrain (synchronize) to the 24-hour light/dark cycle. There is currently no established treatment for sighted patients with N24SWD. To the best of our knowledge, there have been very few reports on the efficacy of ramelteon administered to sighted patients with N24SWD. We report the case of a sighted patient with N24SWD whose free-running sleep-wake pattern recorded by actigraphy was stopped after the administration of a low dose of ramelteon combined with behavioral education.

Original language	English
Pages (from-to)	1265-1267
Number of pages	3
Journal	Journal of Clinical Sleep Medicine
Volume	14
Issue number	7
DOIs	https://doi.org/10.5664/jcsm.7244
Publication status	Published - 15-07-2018
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pulmonary and Respiratory Medicine
Neurology
Clinical Neurology

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abstract = "Non-24-hour sleep-wake rhythm disorder (N24SWD) occurs when the intrinsic circadian pacemaker does not entrain (synchronize) to the 24-hour light/dark cycle. There is currently no established treatment for sighted patients with N24SWD. To the best of our knowledge, there have been very few reports on the efficacy of ramelteon administered to sighted patients with N24SWD. We report the case of a sighted patient with N24SWD whose free-running sleep-wake pattern recorded by actigraphy was stopped after the administration of a low dose of ramelteon combined with behavioral education.",

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AU - Iwata, Nakao

AU - Kitajima, Tsuyoshi

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AB - Non-24-hour sleep-wake rhythm disorder (N24SWD) occurs when the intrinsic circadian pacemaker does not entrain (synchronize) to the 24-hour light/dark cycle. There is currently no established treatment for sighted patients with N24SWD. To the best of our knowledge, there have been very few reports on the efficacy of ramelteon administered to sighted patients with N24SWD. We report the case of a sighted patient with N24SWD whose free-running sleep-wake pattern recorded by actigraphy was stopped after the administration of a low dose of ramelteon combined with behavioral education.

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A Case of Non-24-Hour Sleep-Wake Rhythm Disorder Treated With a Low Dose of Ramelteon and Behavioral Education

Abstract

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