A Case of Pancreatic Metastasis of Osteosarcoma Resected Using Laparoscopic Spleen Preserving Distal Pancreatectomy

Hirochika Toyama, Sadaki Asari, Tadahiro Goto, Sachio Terai, Sachiyo Shirakawa, Yoshihide Nanno, Takuya Mizumoto, Takumi Fukumoto, Tetsuo Ajiki, Masahiro Kido, Motofumi Tanaka, Taku Matsumoto, Hisoka Kinoshita, Kaori Kuramitsu, Yonson Ku

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3 Citations (Scopus)


A 44-year-old woman underwent surgical resection and received preoperative and postoperative chemotherapy for conventional osteosarcoma in the right fibular head. Three years later, follow-up PET-CT revealed accumulation ofFDG in the tail ofthe pancreas. Contrast-enhanced computed tomography showed a 13mm well-circumscribed hypovascular tumor. EUS showed a heterogeneous solid tumor, which was diagnosed as metastasis ofosteosarcoma to the pancreas. Laparoscopic spleen preserving distal pancreatectomy(LAP-SPDP)was performed. Pathologically, the tumor was diagnosed as metastasis ofconventional osteosarcoma to the pancreas. Cells from pancreas islet tissue were detected in the tumor, suggesting invasion ofthe tumor into the pancreatic body and surrounding adipose tissue. Although postoperative chemotherapy was administered, lung metastasis was detected 1.1 years after surgery. Laparoscopic partial resection of the lung metastasis was performed, and the patient is still alive. Metastasis ofosteosarcoma to the pancreas is rare, and there is no report oflaparoscopic approach as a treatment. Herein, we report a case with several references.

Original languageEnglish
Pages (from-to)1988-1990
Number of pages3
JournalGan to kagaku ryoho. Cancer & chemotherapy
Issue number12
Publication statusPublished - 01-11-2016

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research


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