TY - JOUR
T1 - A case of primary amelanotic malignant melanoma of the female urethra
AU - Yoshii, Takahiko
AU - Horiguchi, Akio
AU - Shirotake, Suguru
AU - Tobe, Musashi
AU - Tasaki, Shinsuke
AU - Hayakawa, Masamichi
AU - Sumitomo, Makoto
AU - Asano, Tomohiko
PY - 2010/9
Y1 - 2010/9
N2 - We report a rare case of primary amelanotic malignant melanoma of the female urethra. A 58-year-old female with complaint of nodule on the external urethral meatus was referred to our hospital. Pathological diagnosis of the biopsy specimen from the nodule was malignant melanoma. Computed tomography of the chest and abdomen as well as bone scan showed no evidence of metastasis. Sentinel biopsy from the inguinal lymph nodes revealed no metastasis. Thereafter, the patient underwent radical urethrectomy, whose limits of resection were the bulbocavernosal muscles bilaterally, the arch of the pubic symphysis anteriorly, the anterior vaginal wall posteriorly, and the urethra up to the level of the bladder neck superiorly. The histopathological diagnosis was amelanotic malignant melanoma of the urethra. The patient had received six cycles of DAV-Feron (dacarbazine, nimustine, vincristine, and interferon-β) in an adjuvant setting, and there is no sign of reccurence 25 months after operation.
AB - We report a rare case of primary amelanotic malignant melanoma of the female urethra. A 58-year-old female with complaint of nodule on the external urethral meatus was referred to our hospital. Pathological diagnosis of the biopsy specimen from the nodule was malignant melanoma. Computed tomography of the chest and abdomen as well as bone scan showed no evidence of metastasis. Sentinel biopsy from the inguinal lymph nodes revealed no metastasis. Thereafter, the patient underwent radical urethrectomy, whose limits of resection were the bulbocavernosal muscles bilaterally, the arch of the pubic symphysis anteriorly, the anterior vaginal wall posteriorly, and the urethra up to the level of the bladder neck superiorly. The histopathological diagnosis was amelanotic malignant melanoma of the urethra. The patient had received six cycles of DAV-Feron (dacarbazine, nimustine, vincristine, and interferon-β) in an adjuvant setting, and there is no sign of reccurence 25 months after operation.
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U2 - 10.5980/jpnjurol.101.734
DO - 10.5980/jpnjurol.101.734
M3 - Article
C2 - 20954381
AN - SCOPUS:78049290004
VL - 101
SP - 734
EP - 737
JO - Japanese Journal of Urology
JF - Japanese Journal of Urology
SN - 0021-5287
IS - 6
ER -