A case of progressive sarcomatoid renal cell carcinoma treated with second-line nivolumab after surgery

Shohei Hayakawa, Hiroaki Nakagami, Wataru Nakamura, Tomomi Fujisawa, Masao Kasahara, Hitomi Sasaki, Ryoichi Shiroki

Research output: Contribution to journalArticlepeer-review

Abstract

A 69-year-old man visited a local doctor for fever, pain in the left abdomen, and macroscopic hematuria. Computed tomography (CT) revealed hydronephrosis of the left kidney, and he was referred to our hospital. Detailed examinations suggested left-side pyonephrosis due to urothelial cancer, and left-side total nephroureterectomy was performed. Pathological diagnosis was sarcomatoid renal cell carcinoma. Sunitinib administration was started postoperatively for para-aortic lymph node metastasis, which disappeared. However, metastasis to the common iliac lymph node and liver appeared newly 11 months later. Nivolumab was started in combination with radiation thepapy for the lymph node metastases. The patient remains in a stable disease state as of 21 months after nivolumab administration.

Original languageEnglish
Pages (from-to)265-268
Number of pages4
JournalActa Urologica Japonica
Volume66
Issue number8
DOIs
Publication statusPublished - 08-2020

All Science Journal Classification (ASJC) codes

  • Urology

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