A case of progressive sarcomatoid renal cell carcinoma treated with second-line nivolumab after surgery

Shohei Hayakawa; Hiroaki Nakagami; Wataru Nakamura; Tomomi Fujisawa; Masao Kasahara; Hitomi Sasaki; Ryoichi Shiroki

doi:10.14989/ActaUrolJap_66_8_265

A case of progressive sarcomatoid renal cell carcinoma treated with second-line nivolumab after surgery

Shohei Hayakawa
, Hiroaki Nakagami
, Wataru Nakamura
, Tomomi Fujisawa
, Masao Kasahara
, Hitomi Sasaki
, Ryoichi Shiroki

Research output: Contribution to journal › Article › peer-review

Abstract

A 69-year-old man visited a local doctor for fever, pain in the left abdomen, and macroscopic hematuria. Computed tomography (CT) revealed hydronephrosis of the left kidney, and he was referred to our hospital. Detailed examinations suggested left-side pyonephrosis due to urothelial cancer, and left-side total nephroureterectomy was performed. Pathological diagnosis was sarcomatoid renal cell carcinoma. Sunitinib administration was started postoperatively for para-aortic lymph node metastasis, which disappeared. However, metastasis to the common iliac lymph node and liver appeared newly 11 months later. Nivolumab was started in combination with radiation thepapy for the lymph node metastases. The patient remains in a stable disease state as of 21 months after nivolumab administration.

Original language	English
Pages (from-to)	265-268
Number of pages	4
Journal	Acta Urologica Japonica
Volume	66
Issue number	8
DOIs	https://doi.org/10.14989/ActaUrolJap_66_8_265
Publication status	Published - 08-2020
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

General Medicine

Access to Document

10.14989/ActaUrolJap_66_8_265

Cite this

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title = "A case of progressive sarcomatoid renal cell carcinoma treated with second-line nivolumab after surgery",

abstract = "A 69-year-old man visited a local doctor for fever, pain in the left abdomen, and macroscopic hematuria. Computed tomography (CT) revealed hydronephrosis of the left kidney, and he was referred to our hospital. Detailed examinations suggested left-side pyonephrosis due to urothelial cancer, and left-side total nephroureterectomy was performed. Pathological diagnosis was sarcomatoid renal cell carcinoma. Sunitinib administration was started postoperatively for para-aortic lymph node metastasis, which disappeared. However, metastasis to the common iliac lymph node and liver appeared newly 11 months later. Nivolumab was started in combination with radiation thepapy for the lymph node metastases. The patient remains in a stable disease state as of 21 months after nivolumab administration.",

author = "Shohei Hayakawa and Hiroaki Nakagami and Wataru Nakamura and Tomomi Fujisawa and Masao Kasahara and Hitomi Sasaki and Ryoichi Shiroki",

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language = "English",

volume = "66",

pages = "265--268",

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T1 - A case of progressive sarcomatoid renal cell carcinoma treated with second-line nivolumab after surgery

AU - Hayakawa, Shohei

AU - Nakagami, Hiroaki

AU - Nakamura, Wataru

AU - Fujisawa, Tomomi

AU - Kasahara, Masao

AU - Sasaki, Hitomi

AU - Shiroki, Ryoichi

PY - 2020/8

Y1 - 2020/8

N2 - A 69-year-old man visited a local doctor for fever, pain in the left abdomen, and macroscopic hematuria. Computed tomography (CT) revealed hydronephrosis of the left kidney, and he was referred to our hospital. Detailed examinations suggested left-side pyonephrosis due to urothelial cancer, and left-side total nephroureterectomy was performed. Pathological diagnosis was sarcomatoid renal cell carcinoma. Sunitinib administration was started postoperatively for para-aortic lymph node metastasis, which disappeared. However, metastasis to the common iliac lymph node and liver appeared newly 11 months later. Nivolumab was started in combination with radiation thepapy for the lymph node metastases. The patient remains in a stable disease state as of 21 months after nivolumab administration.

AB - A 69-year-old man visited a local doctor for fever, pain in the left abdomen, and macroscopic hematuria. Computed tomography (CT) revealed hydronephrosis of the left kidney, and he was referred to our hospital. Detailed examinations suggested left-side pyonephrosis due to urothelial cancer, and left-side total nephroureterectomy was performed. Pathological diagnosis was sarcomatoid renal cell carcinoma. Sunitinib administration was started postoperatively for para-aortic lymph node metastasis, which disappeared. However, metastasis to the common iliac lymph node and liver appeared newly 11 months later. Nivolumab was started in combination with radiation thepapy for the lymph node metastases. The patient remains in a stable disease state as of 21 months after nivolumab administration.

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A case of progressive sarcomatoid renal cell carcinoma treated with second-line nivolumab after surgery

Abstract

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All Science Journal Classification (ASJC) codes

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